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1. Construction and validation of a prognostic model based on autophagy-related genes for hepatocellular carcinoma in the Asian population

Author

Yanjie Wang, Sijia Huang, Yingtian Zhang, Yaping Cheng, Liya Dai, Wenwen Gao, Zhengyang Feng, Jialong Tao, and Yusong Zhang

Subjects
Hepatocellular carcinoma, Autophagy-related gene, Prognostic model, The Cancer Genome Atlas database, Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background and objective Hepatocellular carcinoma (HCC), which has a complex pathogenesis and poor prognosis, is one of the most common malignancies worldwide. Hepatitis virus B infection is the most common cause of HCC in Asian patients. Autophagy is the process of digestion and degradation, and studies have shown that autophagy-associated effects are closely related to the development of HCC. In this study, we aimed to construct a prognostic model based on autophagy-related genes (ARGs) for the Asian HCC population to provide new ideas for the clinical management of HCC in the Asian population. Methods The clinical information and transcriptome data of Asian patients with HCC were downloaded from The Cancer Genome Atlas (TCGA) database, and 206 ARGs were downloaded from the human autophagy database (HADB). We performed differential and Cox regression analyses to construct a risk score model. The accuracy of the model was validated by using the Kaplan–Meier (K–M) survival curve, receiver operating characteristic (ROC) curve, and univariate and multivariate Cox independent prognostic analyses. The results Thirteen ARGs that were significantly associated with prognosis were finally identified by univariate and multivariate Cox regression analyses. The K–M survival curves showed that the survival rate of the low-risk group was significantly higher than that of the high-risk group (p

Published
2023
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2. Mass testing and characterization of 20-inch PMTs for JUNO

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Abid Aleem, Tsagkarakis Alexandros, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Ilya Butorov, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Chi Chan, Jinfan Chang, Yun Chang, Guoming Chen, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yixue Chen, Yu Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Yu Chin Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Zhengyong Fei, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Kaixuan Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Daozheng Li, Demin Li, Fei Li, Fule Li, Gaosong Li, Huiling Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Yufeng Li, Zepeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, Hao Liang, Jiajun Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Daibin Luo, Fengjiao Luo, Guang Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Luca Pelicci, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Mariia Redchuk, Bin Ren, Jie Ren, Barbara Ricci, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Utane Sawangwit, Julia Sawatzki, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Jun Su, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Eric Theisen, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiang Xiao, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Na Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Baobiao Yue, Noman Zafar, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Guoqing Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Mohan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Xueyao Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Dongqin Zheng, Hua Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Main goal of the JUNO experiment is to determine the neutrino mass ordering using a 20 kt liquid-scintillator detector. Its key feature is an excellent energy resolution of at least 3% at 1 MeV, for which its instruments need to meet a certain quality and thus have to be fully characterized. More than 20,000 20-inch PMTs have been received and assessed by JUNO after a detailed testing program which began in 2017 and elapsed for about four years. Based on this mass characterization and a set of specific requirements, a good quality of all accepted PMTs could be ascertained. This paper presents the performed testing procedure with the designed testing systems as well as the statistical characteristics of all 20-inch PMTs intended to be used in the JUNO experiment, covering more than fifteen performance parameters including the photocathode uniformity. This constitutes the largest sample of 20-inch PMTs ever produced and studied in detail to date, i.e. 15,000 of the newly developed 20-inch MCP-PMTs from Northern Night Vision Technology Co. (NNVT) and 5000 of dynode PMTs from Hamamatsu Photonics K. K.(HPK).

Published
2022
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3. Model-independent Approach of the JUNO 8B Solar Neutrino Program

Author

Jie Zhao, Baobiao Yue, Haoqi Lu, Yufeng Li, Jiajie Ling, Zeyuan Yu, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Abid Aleem, Tsagkarakis Alexandros, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Weidong Bai, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Jose Busto, Ilya Butorov, Anatael Cabrera, Barbara Caccianiga, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Chi Chan, Jinfan Chang, Yun Chang, Guoming Chen, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yixue Chen, Yu Chen, Zhiyuan Chen, Zikang Chen, Jie Cheng, Yaping Cheng, Alexander Chepurnov, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Marta Colomer Molla, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Zhengyong Fei, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Maxim Gromov, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Yuduo Guan, Nunzio Guardone, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Yuxiang Hu, Zhuojun Hu, Guihong Huang, Hanxiong Huang, Kaixuan Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Ignacio Jeria, Xiaolu Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Xiaoping Jing, Cécile Jollet, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Amina Khatun, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Daozheng Li, Demin Li, Fei Li, Fule Li, Gaosong Li, Huiling Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Rui Li, Shanfeng Li, Tao Li, Teng Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yichen Li, Zepeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Zonghai Li, Hao Liang, Jiajun Liao, Ayut Limphirat, Guey-Lin Lin, Shengxin Lin, Tao Lin, Ivano Lippi, Fang Liu, Haidong Liu, Haotian Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Daibin Luo, Fengjiao Luo, Guang Luo, Shu Luo, Wuming Luo, Xiaojie Luo, Vladimir Lyashuk, Bangzheng Ma, Bing Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Jingyu Mai, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Alexey Nikolaev, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Yu Peng, Zhaoyuan Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Mariia Redchuk, Bin Ren, Jie Ren, Barbara Ricci, Mariam Rifai, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Xichao Ruan, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Utane Sawangwit, Julia Sawatzki, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Jun Su, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Zhengyang Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Katharina von Sturm, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiang Xiao, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhao Xin, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Jiaxuan Ye, Mei Ye, Ziping Ye, Frédéric Yermia, Na Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zezhong Yu, Cenxi Yuan, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Noman Zafar, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Bin Zhang, Binting Zhang, Feiyang Zhang, Guoqing Zhang, Honghao Zhang, Jialiang Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Mohan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xin Zhang, Xuantong Zhang, Xueyao Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yu Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Rong Zhao, Runze Zhao, Shujun Zhao, Dongqin Zheng, Hua Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Jingsen Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Solar neutrinos, Astrophysics, QB460-466
Abstract

The physics potential of detecting ^8 B solar neutrinos will be exploited at the Jiangmen Underground Neutrino Observatory (JUNO), in a model-independent manner by using three distinct channels of the charged current (CC), neutral current (NC), and elastic scattering (ES) interactions. Due to the largest-ever mass of ^13 C nuclei in the liquid scintillator detectors and the expected low background level, ^8 B solar neutrinos are observable in the CC and NC interactions on ^13 C for the first time. By virtue of optimized event selections and muon veto strategies, backgrounds from the accidental coincidence, muon-induced isotopes, and external backgrounds can be greatly suppressed. Excellent signal-to-background ratios can be achieved in the CC, NC, and ES channels to guarantee the observation of the ^8 B solar neutrinos. From the sensitivity studies performed in this work, we show that JUNO, with 10 yr of data, can reach the 1 σ precision levels of 5%, 8%, and 20% for the ^8 B neutrino flux, ${\sin }^{2}{\theta }_{12}$ , and ${\rm{\Delta }}{m}_{21}^{2}$ , respectively. Probing the details of both solar physics and neutrino physics would be unique and helpful. In addition, when combined with the Sudbury Neutrino Observatory measurement, the world's best precision of 3% is expected for the measurement of the ^8 B neutrino flux.

Published
2024
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4. Damping signatures at JUNO, a medium-baseline reactor neutrino oscillation experiment

Author

The JUNO collaboration, Jun Wang, Jiajun Liao, Wei Wang, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Nikita Balashov, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Riccardo Callegari, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Ran Du, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Arsenii Gavrikov, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Wei Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Arslan Lukanov, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Roberto Carlos Mandujano, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Marco Danilo Claudio Torri, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Moritz Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Kaile Wen, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We study damping signatures at the Jiangmen Underground Neutrino Observatory (JUNO), a medium-baseline reactor neutrino oscillation experiment. These damping signatures are motivated by various new physics models, including quantum decoherence, ν 3 decay, neutrino absorption, and wave packet decoherence. The phenomenological effects of these models can be characterized by exponential damping factors at the probability level. We assess how well JUNO can constrain these damping parameters and how to disentangle these different damping signatures at JUNO. Compared to current experimental limits, JUNO can significantly improve the limits on τ 3/m 3 in the ν 3 decay model, the width of the neutrino wave packet σ x , and the intrinsic relative dispersion of neutrino momentum σ rel.

Published
2022
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5. The design and sensitivity of JUNO’s scintillator radiopurity pre-detector OSIRIS

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Jiajun Liao, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, MinhThuan NguyenThi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangpu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The OSIRIS detector is a subsystem of the liquid scintillator filling chain of the JUNO reactor neutrino experiment. Its purpose is to validate the radiopurity of the scintillator to assure that all components of the JUNO scintillator system work to specifications and only neutrino-grade scintillator is filled into the JUNO Central Detector. The aspired sensitivity level of $$10^{-16}\hbox { g/g}$$ 10 - 16 g/g of $$^{238}\hbox {U}$$ 238 U and $$^{232}\hbox {Th}$$ 232 Th requires a large ( $$\sim 20\,\hbox {m}^3$$ ∼ 20 m 3 ) detection volume and ultralow background levels. The present paper reports on the design and major components of the OSIRIS detector, the detector simulation as well as the measuring strategies foreseen and the sensitivity levels to U/Th that can be reached in this setup.

Published
2021
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6. Radioactivity control strategy for the JUNO detector

Author

The JUNO collaboration, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Davide Basilico, Eric Baussan, Marco Bellato, Antonio Bergnoli, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Oliviero Cremonesi, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Rebin Karaparambil, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jiajun Liao, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Matthias Mayer, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Paolo Montini, Michele Montuschi, Axel Müller, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Moritz Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Xiaochuan Xie, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Chengfeng Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jin Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kangfu Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract JUNO is a massive liquid scintillator detector with a primary scientific goal of determining the neutrino mass ordering by studying the oscillated anti-neutrino flux coming from two nuclear power plants at 53 km distance. The expected signal anti-neutrino interaction rate is only 60 counts per day (cpd), therefore a careful control of the background sources due to radioactivity is critical. In particular, natural radioactivity present in all materials and in the environment represents a serious issue that could impair the sensitivity of the experiment if appropriate countermeasures were not foreseen. In this paper we discuss the background reduction strategies undertaken by the JUNO collaboration to reduce at minimum the impact of natural radioactivity. We describe our efforts for an optimized experimental design, a careful material screening and accurate detector production handling, and a constant control of the expected results through a meticulous Monte Carlo simulation program. We show that all these actions should allow us to keep the background count rate safely below the target value of 10 Hz (i.e. ∼1 cpd accidental background) in the default fiducial volume, above an energy threshold of 0.7 MeV.

Published
2021
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7. JUNO sensitivity to low energy atmospheric neutrino spectra

Author

Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Eric Baussan, Marco Bellato, Antonio Bergnoli, Enrico Bernieri, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Alexey Chetverikov, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Dmitry Dolzhikov, Georgy Donchenko, Jianmeng Dong, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Wenxing Fang, Marco Fargetta, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Maxim Gonchar, Guanghua Gong, Hui Gong, Oleg Gorchakov, Yuri Gornushkin, Alexandre Göttel, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Sohaib Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Qinhua Huang, Wenhao Huang, Xin Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Antonio Insolia, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Ignacio Jeria, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Waseem Khan, Khanchai Khosonthongkee, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Zinovy Krumshteyn, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Mengzhao Li, Min Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhaohan Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Xiwen Liu, Yan Liu, Yunzhe Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Bangzheng Ma, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Salvatore Monforte, Paolo Montini, Michele Montuschi, Axel Müller, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Minh Thuan Nguyen Thi, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Rainer Othegraven, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Oliver Pilarczyk, Luis Felipe Piñeres Rico, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Zhen Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Usman Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Taras Rezinko, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Giuseppe Salamanna, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Jacky Schuler, Cédric Schwab, Konstantin Schweizer, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Arina Shaydurova, Jingyan Shi, Yanan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Sergey Sokolov, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondřej Šrámek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Nikita Ushakov, Johannes van den Boom, Stefan van Waasen, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Moritz Cornelius Vollbrecht, Cristina Volpe, Vit Vorobel, Dmitriy Voronin, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Muhammad Waqas, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Wenlu Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Wenjie Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Hangkun Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Taylor Yan, Wenqi Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Na Yin, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Zezhong Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Vitalii Zavadskyi, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Aiqiang Zhang, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Jinnan Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Xueyao Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Tong Zhou, Xiang Zhou, Jiang Zhu, Kejun Zhu, Zhihang Zhu, Bo Zhuang, Honglin Zhuang, Liang Zong, Jiaheng Zou, and The JUNO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Atmospheric neutrinos are one of the most relevant natural neutrino sources that can be exploited to infer properties about cosmic rays and neutrino oscillations. The Jiangmen Underground Neutrino Observatory (JUNO) experiment, a 20 kton liquid scintillator detector with excellent energy resolution is currently under construction in China. JUNO will be able to detect several atmospheric neutrinos per day given the large volume. A study on the JUNO detection and reconstruction capabilities of atmospheric $$\nu _e$$ ν e and $$\nu _\mu $$ ν μ fluxes is presented in this paper. In this study, a sample of atmospheric neutrino Monte Carlo events has been generated, starting from theoretical models, and then processed by the detector simulation. The excellent timing resolution of the 3” PMT light detection system of JUNO detector and the much higher light yield for scintillation over Cherenkov allow to measure the time structure of the scintillation light with very high precision. Since $$\nu _e$$ ν e and $$\nu _\mu $$ ν μ interactions produce a slightly different light pattern, the different time evolution of light allows to discriminate the flavor of primary neutrinos. A probabilistic unfolding method has been used, in order to infer the primary neutrino energy spectrum from the detector experimental observables. The simulated spectrum has been reconstructed between 100 MeV and 10 GeV, showing a great potential of the detector in the atmospheric low energy region.

Published
2021
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8. Catalytic asymmetric nucleophilic fluorination using BF3·Et2O as fluorine source and activating reagent

Author

Weiwei Zhu, Xiang Zhen, Jingyuan Wu, Yaping Cheng, Junkai An, Xingyu Ma, Jikun Liu, Yuji Qin, Hao Zhu, Jijun Xue, and Xianxing Jiang

Subjects
Science
Abstract

Catalytic asymmetric fluorination remains elusive, especially the longstanding stereochemical challenges which exist in BF3Et2O-based fluorinations. Here the authors show a catalytic asymmetric nucleophilic fluorination using BF3·Et2O as the fluorine reagent in the presence of chiral iodine catalyst.

Published
2021
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9. Calibration strategy of the JUNO experiment

Author

The JUNO collaboration, Angel Abusleme, Thomas Adam, Shakeel Ahmad, Rizwan Ahmed, Sebastiano Aiello, Muhammad Akram, Fengpeng An, Guangpeng An, Qi An, Giuseppe Andronico, Nikolay Anfimov, Vito Antonelli, Tatiana Antoshkina, Burin Asavapibhop, João Pedro Athayde Marcondes de André, Didier Auguste, Andrej Babic, Wander Baldini, Andrea Barresi, Eric Baussan, Marco Bellato, Antonio Bergnoli, Enrico Bernieri, Thilo Birkenfeld, Sylvie Blin, David Blum, Simon Blyth, Anastasia Bolshakova, Mathieu Bongrand, Clément Bordereau, Dominique Breton, Augusto Brigatti, Riccardo Brugnera, Riccardo Bruno, Antonio Budano, Mario Buscemi, Jose Busto, Ilya Butorov, Anatael Cabrera, Hao Cai, Xiao Cai, Yanke Cai, Zhiyan Cai, Antonio Cammi, Agustin Campeny, Chuanya Cao, Guofu Cao, Jun Cao, Rossella Caruso, Cédric Cerna, Jinfan Chang, Yun Chang, Pingping Chen, Po-An Chen, Shaomin Chen, Shenjian Chen, Xurong Chen, Yi-Wen Chen, Yixue Chen, Yu Chen, Zhang Chen, Jie Cheng, Yaping Cheng, Davide Chiesa, Pietro Chimenti, Artem Chukanov, Anna Chuvashova, Gérard Claverie, Catia Clementi, Barbara Clerbaux, Selma Conforti Di Lorenzo, Daniele Corti, Salvatore Costa, Flavio Dal Corso, Olivia Dalager, Christophe De La Taille, Jiawei Deng, Zhi Deng, Ziyan Deng, Wilfried Depnering, Marco Diaz, Xuefeng Ding, Yayun Ding, Bayu Dirgantara, Sergey Dmitrievsky, Tadeas Dohnal, Georgy Donchenko, Jianmeng Dong, Damien Dornic, Evgeny Doroshkevich, Marcos Dracos, Frédéric Druillole, Shuxian Du, Stefano Dusini, Martin Dvorak, Timo Enqvist, Heike Enzmann, Andrea Fabbri, Lukas Fajt, Donghua Fan, Lei Fan, Can Fang, Jian Fang, Marco Fargetta, Anna Fatkina, Dmitry Fedoseev, Vladko Fekete, Li-Cheng Feng, Qichun Feng, Richard Ford, Andrey Formozov, Amélie Fournier, Haonan Gan, Feng Gao, Alberto Garfagnini, Alexandre Göttel, Christoph Genster, Marco Giammarchi, Agnese Giaz, Nunzio Giudice, Franco Giuliani, Maxim Gonchar, Guanghua Gong, Hui Gong, Oleg Gorchakov, Yuri Gornushkin, Marco Grassi, Christian Grewing, Vasily Gromov, Minghao Gu, Xiaofei Gu, Yu Gu, Mengyun Guan, Nunzio Guardone, Maria Gul, Cong Guo, Jingyuan Guo, Wanlei Guo, Xinheng Guo, Yuhang Guo, Paul Hackspacher, Caren Hagner, Ran Han, Yang Han, Muhammad Hassan, Miao He, Wei He, Tobias Heinz, Patrick Hellmuth, Yuekun Heng, Rafael Herrera, Daojin Hong, YuenKeung Hor, Shaojing Hou, Yee Hsiung, Bei-Zhen Hu, Hang Hu, Jianrun Hu, Jun Hu, Shouyang Hu, Tao Hu, Zhuojun Hu, Chunhao Huang, Guihong Huang, Hanxiong Huang, Qinhua Huang, Wenhao Huang, Xingtao Huang, Yongbo Huang, Jiaqi Hui, Lei Huo, Wenju Huo, Cédric Huss, Safeer Hussain, Antonio Insolia, Ara Ioannisian, Roberto Isocrate, Beatrice Jelmini, Kuo-Lun Jen, Xiaolu Ji, Xingzhao Ji, Huihui Jia, Junji Jia, Siyu Jian, Di Jiang, Xiaoshan Jiang, Ruyi Jin, Xiaoping Jing, Cécile Jollet, Jari Joutsenvaara, Sirichok Jungthawan, Leonidas Kalousis, Philipp Kampmann, Li Kang, Michael Karagounis, Narine Kazarian, Amir Khan, Waseem Khan, Khanchai Khosonthongkee, Patrick Kinz, Denis Korablev, Konstantin Kouzakov, Alexey Krasnoperov, Svetlana Krokhaleva, Zinovy Krumshteyn, Andre Kruth, Nikolay Kutovskiy, Pasi Kuusiniemi, Tobias Lachenmaier, Cecilia Landini, Sébastien Leblanc, Victor Lebrin, Frederic Lefevre, Ruiting Lei, Rupert Leitner, Jason Leung, Demin Li, Fei Li, Fule Li, Haitao Li, Huiling Li, Jiaqi Li, Jin Li, Kaijie Li, Mengzhao Li, Nan Li, Qingjiang Li, Ruhui Li, Shanfeng Li, Shuaijie Li, Tao Li, Weidong Li, Weiguo Li, Xiaomei Li, Xiaonan Li, Xinglong Li, Yi Li, Yufeng Li, Zhibing Li, Ziyuan Li, Hao Liang, Jingjing Liang, Daniel Liebau, Ayut Limphirat, Sukit Limpijumnong, Guey-Lin Lin, Shengxin Lin, Tao Lin, Jiajie Ling, Ivano Lippi, Fang Liu, Haidong Liu, Hongbang Liu, Hongjuan Liu, Hongtao Liu, Hu Liu, Hui Liu, Jianglai Liu, Jinchang Liu, Min Liu, Qian Liu, Qin Liu, Runxuan Liu, Shuangyu Liu, Shubin Liu, Shulin Liu, Xiaowei Liu, Yan Liu, Alexey Lokhov, Paolo Lombardi, Claudio Lombardo, Kai Loo, Chuan Lu, Haoqi Lu, Jingbin Lu, Junguang Lu, Shuxiang Lu, Xiaoxu Lu, Bayarto Lubsandorzhiev, Sultim Lubsandorzhiev, Livia Ludhova, Fengjiao Luo, Guang Luo, Pengwei Luo, Shu Luo, Wuming Luo, Vladimir Lyashuk, Qiumei Ma, Si Ma, Xiaoyan Ma, Xubo Ma, Jihane Maalmi, Yury Malyshkin, Fabio Mantovani, Francesco Manzali, Xin Mao, Yajun Mao, Stefano M. Mari, Filippo Marini, Sadia Marium, Cristina Martellini, Gisele Martin-Chassard, Agnese Martini, Davit Mayilyan, Axel Müller, Ints Mednieks, Yue Meng, Anselmo Meregaglia, Emanuela Meroni, David Meyhöfer, Mauro Mezzetto, Jonathan Miller, Lino Miramonti, Salvatore Monforte, Paolo Montini, Michele Montuschi, Nikolay Morozov, Waqas Muhammad, Pavithra Muralidharan, Massimiliano Nastasi, Dmitry V. Naumov, Elena Naumova, Diana Navas-Nicolas, Igor Nemchenok, Feipeng Ning, Zhe Ning, Hiroshi Nunokawa, Lothar Oberauer, Juan Pedro Ochoa-Ricoux, Alexander Olshevskiy, Domizia Orestano, Fausto Ortica, Hsiao-Ru Pan, Alessandro Paoloni, Nina Parkalian, Sergio Parmeggiano, Teerapat Payupol, Yatian Pei, Nicomede Pelliccia, Anguo Peng, Haiping Peng, Frédéric Perrot, Pierre-Alexandre Petitjean, Fabrizio Petrucci, Luis Felipe Piñeres Rico, Oliver Pilarczyk, Artyom Popov, Pascal Poussot, Wathan Pratumwan, Ezio Previtali, Fazhi Qi, Ming Qi, Sen Qian, Xiaohui Qian, Hao Qiao, Zhonghua Qin, Shoukang Qiu, Muhammad Rajput, Gioacchino Ranucci, Neill Raper, Alessandra Re, Henning Rebber, Abdel Rebii, Bin Ren, Jie Ren, Taras Rezinko, Barbara Ricci, Markus Robens, Mathieu Roche, Narongkiat Rodphai, Aldo Romani, Bedřich Roskovec, Christian Roth, Xiangdong Ruan, Xichao Ruan, Saroj Rujirawat, Arseniy Rybnikov, Andrey Sadovsky, Paolo Saggese, Giuseppe Salamanna, Simone Sanfilippo, Anut Sangka, Nuanwan Sanguansak, Utane Sawangwit, Julia Sawatzki, Fatma Sawy, Michaela Schever, Jacky Schuler, Cédric Schwab, Konstantin Schweizer, Dmitry Selivanov, Alexandr Selyunin, Andrea Serafini, Giulio Settanta, Mariangela Settimo, Zhuang Shao, Vladislav Sharov, Jingyan Shi, Vitaly Shutov, Andrey Sidorenkov, Fedor Šimkovic, Chiara Sirignano, Jaruchit Siripak, Monica Sisti, Maciej Slupecki, Mikhail Smirnov, Oleg Smirnov, Thiago Sogo-Bezerra, Julanan Songwadhana, Boonrucksar Soonthornthum, Albert Sotnikov, Ondrej Sramek, Warintorn Sreethawong, Achim Stahl, Luca Stanco, Konstantin Stankevich, Dušan Štefánik, Hans Steiger, Jochen Steinmann, Tobias Sterr, Matthias Raphael Stock, Virginia Strati, Alexander Studenikin, Gongxing Sun, Shifeng Sun, Xilei Sun, Yongjie Sun, Yongzhao Sun, Narumon Suwonjandee, Michal Szelezniak, Jian Tang, Qiang Tang, Quan Tang, Xiao Tang, Alexander Tietzsch, Igor Tkachev, Tomas Tmej, Konstantin Treskov, Andrea Triossi, Giancarlo Troni, Wladyslaw Trzaska, Cristina Tuve, Stefan van Waasen, Johannes van den Boom, Guillaume Vanroyen, Nikolaos Vassilopoulos, Vadim Vedin, Giuseppe Verde, Maxim Vialkov, Benoit Viaud, Cristina Volpe, Vit Vorobel, Lucia Votano, Pablo Walker, Caishen Wang, Chung-Hsiang Wang, En Wang, Guoli Wang, Jian Wang, Jun Wang, Kunyu Wang, Lu Wang, Meifen Wang, Meng Wang, Ruiguang Wang, Siguang Wang, Wei Wang, Wenshuai Wang, Xi Wang, Xiangyue Wang, Yangfu Wang, Yaoguang Wang, Yi Wang, Yifang Wang, Yuanqing Wang, Yuman Wang, Zhe Wang, Zheng Wang, Zhimin Wang, Zongyi Wang, Apimook Watcharangkool, Lianghong Wei, Wei Wei, Yadong Wei, Liangjian Wen, Christopher Wiebusch, Steven Chan-Fai Wong, Bjoern Wonsak, Diru Wu, Fangliang Wu, Qun Wu, Wenjie Wu, Zhi Wu, Michael Wurm, Jacques Wurtz, Christian Wysotzki, Yufei Xi, Dongmei Xia, Mengjiao Xiao, Yuguang Xie, Zhangquan Xie, Zhizhong Xing, Benda Xu, Cheng Xu, Donglian Xu, Fanrong Xu, Jilei Xu, Jing Xu, Meihang Xu, Yin Xu, Yu Xu, Baojun Yan, Xiongbo Yan, Yupeng Yan, Anbo Yang, Changgen Yang, Huan Yang, Jie Yang, Lei Yang, Xiaoyu Yang, Yifan Yang, Haifeng Yao, Zafar Yasin, Jiaxuan Ye, Mei Ye, Ziping Ye, Ugur Yegin, Frédéric Yermia, Peihuai Yi, Xiangwei Yin, Zhengyun You, Boxiang Yu, Chiye Yu, Chunxu Yu, Hongzhao Yu, Miao Yu, Xianghui Yu, Zeyuan Yu, Chengzhuo Yuan, Ying Yuan, Zhenxiong Yuan, Ziyi Yuan, Baobiao Yue, Noman Zafar, Andre Zambanini, Shan Zeng, Tingxuan Zeng, Yuda Zeng, Liang Zhan, Feiyang Zhang, Guoqing Zhang, Haiqiong Zhang, Honghao Zhang, Jiawen Zhang, Jie Zhang, Jingbo Zhang, Peng Zhang, Qingmin Zhang, Shiqi Zhang, Shu Zhang, Tao Zhang, Xiaomei Zhang, Xuantong Zhang, Yan Zhang, Yinhong Zhang, Yiyu Zhang, Yongpeng Zhang, Yuanyuan Zhang, Yumei Zhang, Zhenyu Zhang, Zhijian Zhang, Fengyi Zhao, Jie Zhao, Rong Zhao, Shujun Zhao, Tianchi Zhao, Dongqin Zheng, Hua Zheng, Minshan Zheng, Yangheng Zheng, Weirong Zhong, Jing Zhou, Li Zhou, Nan Zhou, Shun Zhou, Xiang Zhou, Jiang Zhu, Kejun Zhu, Honglin Zhuang, Liang Zong, and Jiaheng Zou

Subjects
Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-positional calibration program, in combination with a novel dual calorimetry technique exploiting two independent photosensors and readout systems, we demonstrate that the JUNO central detector can achieve a better than 1% energy linearity and a 3% effective energy resolution, required by the neutrino mass ordering determination.

Published
2021
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10. N-Heterocyclic Carbene Copper (I) Complexes Incorporating Pyrene Chromophore: Synthesis, Crystal Structure, and Luminescent Properties

Author

Yaping Cheng, Geoffrey Gontard, Abderrahim Khatyr, Michael Knorr, and Hani Amouri

Subjects
luminescent copper complexes, N-heterocyclic carbenes, blue emitters, X-ray structural determination, Organic chemistry, QD241-441
Abstract

Luminescent N-heterocyclic carbene chloride copper (I) complexes incorporating pyrene chromophore (1-Pyrenyl-NHC-R)-Cu-Cl, (3, 4) have been prepared and fully characterized. Two complexes were prepared with R = methyl (3) and R = naphthyl groups (4) at the nitrogen center of the carbene unit to tune their electronic properties. The molecular structures of 3 and 4 have been elucidated by X-ray diffraction and confirm the formation of the target compounds. Preliminary results reveal that all compounds including the imidazole-pyrenyl ligand 1 are emissive in the blue region at room temperature in solution and in solid-state. All complexes display quantum yields comparable or higher when compared to the parent pyrene molecule. Interestingly replacement of the methyl by naphthyl group increases the quantum yield by almost two-folds. These compounds might show promise for applications as optical displays.

Published
2023
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11. Simulation Study on the Environmental Impact of Rare Earth Ore Development on Groundwater in Hilly Areas: A Case Study in Nuodong, China

Author

Hongqiu He, Huimei Shan, Deke Mo, Yunquan Liu, Sanxi Peng, Yaping Cheng, Meng Chen, and Zhiwei Yan

Subjects
rare earth ore, groundwater, numerical simulation, ammonia-nitrogen pollutant, Hydraulic engineering, TC1-978, Water supply for domestic and industrial purposes, TD201-500
Abstract

Mineral extraction can significantly affect the groundwater flow and hydrochemical environment. However, for hilly areas, significant ground elevation changes and complex geological conditions make it difficult to accurately analyze and predict the impact of mineral mining. This study takes the Nuodong rare earth mining area as an example. Based on field investigations and experiments, GOCAD software (version 2022) was used to establish a geological model in combination with GMS numerical simulation software, which was used to build a groundwater flow model and a solute transport model. The flow model in the hilly area indicated that the absolute error between the simulated and measured water levels of each observation well is 0.554 m. The solute-transport model showed that the maximum pollutant concentration of ammonia-nitrogen (NH3-N) in the liquid injection area, stream area, and village area monitoring wells reaches 139.15, 27.9, and 3-N, which threatens the safety of the water for mine area residents. To control pollutant transport, two stages of pumping were adopted to reduce NH3-N concentrations in groundwater. After adopting the first stage, the peak concentration of the stream area monitoring wells decreased significantly, with the maximum peak concentration decreasing from 27.9 mg/L to 5.51 mg/L. Based on the results of the first stage of the pump-out treatment, a second stage was adopted. The model results showed that the peak concentration of NH3-N pollutants discharged into the stream is less than 0.5 mg/L. The results provide a theoretical basis and reference for groundwater monitoring and pollution control after mining in this area.

Published
2023
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12. Secure data storage based on blockchain and coding in edge computing

Author

Yongjun Ren, Yan Leng, Yaping Cheng, and Jin Wang

Subjects
smart computing, edge computing, secure data storage, blockchain, coding, Biotechnology, TP248.13-248.65, Mathematics, QA1-939
Abstract

Edge computing is an important tool for smart computing, which brings convenience to data processing as well as security problems. In particular, the security of data storage under edge computing has become an obstacle to its widespread use. To solve the problem, the mechanism combing blockchain with regeneration coding is proposed to improve the security and reliability of stored data under edge computing. Our contribution is as follows. 1) According to the three-tier edge computing architecture and data security storage requirements, we proposed hybrid storage architecture and model specifically adapted to edge computing. 2) Making full use of the data storage advantages of edge network devices and cloud storage servers, we build a global blockchain in the cloud service layer and local blockchain is built on the terminals of the Internet of things. Moreover, the regeneration coding is utilized to further improve the reliability of data storage in blockchains. 3) Our scheme provides a mechanism for periodically validating hash values of data to ensure the integrity of data stored in global blockchain.

Published
2019
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13. Prussian Blue and Carbon-Dot Hybrids for Enhanced Electrochromic Performance

Author

Jia Chu, Yaping Cheng, Xue Li, Fan Yang, Shanxin Xiong, and Zhao Zhang

Subjects
Prussian blue, carbon dot, hydrothermal, electrochromic, Technology, Electrical engineering. Electronics. Nuclear engineering, TK1-9971, Engineering (General). Civil engineering (General), TA1-2040, Microscopy, QH201-278.5, Descriptive and experimental mechanics, QC120-168.85
Abstract

In this study, Prussian blue@Carbon-dot (PB@C-dot) hybrids have been developed by one-step hydrothermal method. The incorporation of C-dots into Prussian blue thin film as a way of improving its electrochromic performance was investigated. The structure of the PB@C-dot hybrid was characterized through X-ray diffraction, Raman spectroscopy and scanning electron microscopy. The electrochromic properties showed that incorporation of 10 mL C-dots into the film showed higher optical contrast of 1.6 and superior coloration/bleaching response of 10 and 3 s. It is proposed that the C-dots component used in the construction of the PB@C-dot hybrid plays a key role to achieve superior electrochromic performance.

Published
2021
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14. Fabrication of Carbohydrate Chips Based on Polydopamine for Real-Time Determination of Carbohydrate–Lectin Interactions by QCM Biosensor

Author

Kun Shang, Siyu Song, Yaping Cheng, Lili Guo, Yuxin Pei, Xiaomeng Lv, Teodor Aastrup, and Zhichao Pei

Subjects
polydopamine, amino-carbohydrates, carbohydrate chips, QCM biosensor, carbohydrate–lectin interactions, Organic chemistry, QD241-441
Abstract

A novel approach for preparing carbohydrate chips based on polydopamine (PDA) surface to study carbohydrate⁻lectin interactions by quartz crystal microbalance (QCM) biosensor instrument has been developed. The amino-carbohydrates were immobilized on PDA-coated quartz crystals via Schiff base reaction and/or Michael addition reaction. The resulting carbohydrate-chips were applied to QCM biosensor instrument with flow-through system for real-time detection of lectin⁻carbohydrate interactions. A series of plant lectins, including wheat germ agglutinin (WGA), concanavalin A (Con A), Ulex europaeus agglutinin I (UEA-I), soybean agglutinin (SBA), and peanut agglutinin (PNA), were evaluated for the binding to different kinds of carbohydrate chips. Clearly, the results show that the predicted lectin selectively binds to the carbohydrates, which demonstrates the applicability of the approach. Furthermore, the kinetics of the interactions between Con A and mannose, WGA and N-Acetylglucosamine were studied, respectively. This study provides an efficient approach to preparing carbohydrate chips based on PDA for the lectin⁻carbohydrate interactions study.

Published
2018
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19. A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumors

Author

Yanling Wu, Quanxiao Li, Yu Kong, Zhi Wang, Cheng Lei, Ji Li, Lulu Ding, Chunyu Wang, Yaping Cheng, Yaozhu Wei, Yuanlin Song, Zhenlin Yang, Chao Tu, Yu Ding, and Tianlei Ying

Subjects
Pharmacology, Immunoconjugates, Cell Line, Tumor, Drug Discovery, Genetics, Humans, Molecular Medicine, Antineoplastic Agents, Single-Domain Antibodies, Molecular Biology
Abstract

The inefficient tumor penetration of therapeutic antibodies has hampered their effective use in treating solid tumors. Here, we report the identification of a fully human single-domain antibody (UdAb), designated as n501, targeting the oncofetal antigen 5T4. The high-resolution crystal structure indicates that n501 adopts a compact structure very similar to that of camelid nanobodies, and binds tightly to all eight leucine-rich repeats of 5T4. Furthermore, the UdAb n501 exhibits exceptionally high stability, with no apparent activity changes over 4 weeks of storage at various temperatures. Importantly, the UdAb-based antibody-drug conjugate (n501-SN38) showed much deeper tumor penetration, significantly higher tumor uptake, and faster accumulation at tumor sites than conventional IgG1-based antibody-drug conjugate (m603-SN38), resulting in improved tumor inhibition. These results highlight the potential of UdAb-based antibody-drug conjugates as a potential class of antitumor therapeutics with characteristics of high stability and strong tumor penetration for the effective treatment of solid tumors.

Published
2022

20. Corrosion mechanism of cement-bonded Al2O3–MgAl2O4 pre-cast castables in contact with molten steel and slag

Author

Junli Xiao, Yaping Cheng, Junfeng Chen, Nan Li, Shaowei Zhang, Yuanyuan Li, Mithun Nath, Yu Zhang, Lijun Zheng, and Yaowu Wei

Subjects
Cement, Materials science, Process Chemistry and Technology, Metallurgy, Slag, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Corrosion, Mechanism (engineering), visual_art, Materials Chemistry, Ceramics and Composites, Molten steel, visual_art.visual_art_medium
Published
2022

23. Degradation behaviors of cement-free corundum-spinel castables in Ruhrstahl Heraeus refining ladle: Role of infiltrated steel

Author

Junfeng Chen, Junli Xiao, Guangping Liu, Yuanyuan Li, Yaowu Wei, Nan Li, Guangqiang Li, Yaping Cheng, Shaowei Zhang, and Yu Zhang

Subjects
Cement, Ladle, Materials science, Process Chemistry and Technology, Aluminate, Spinel, Metallurgy, Composite number, Slag, engineering.material, Spall, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Corrosion, chemistry.chemical_compound, chemistry, visual_art, Materials Chemistry, Ceramics and Composites, engineering, visual_art.visual_art_medium
Abstract

Chemical attacks and structural spalling dominated the degradation process of the refractory lining in refining ladle. In the present work, we have fabricated a cement-free gel-bonded corundum-spinel castables and examined the degradation behavior in contact with the molten steel/slag. Further, the role of infiltrated steel/slag associated with cracks on the spalling behavior were elucidated. The stress cracks formed on the corroded interface, providing a permeation pathway for molten corrosive species and acting as a sub-surface for further corrosion. Infiltrated steel contributed to the formation of composite (Mg, Fe)Al2O4 spinel and led to an additional corrosion and induced a large structural spalling. Besides, macro-scale structural spalling of the refractory lining and microscale spalling of aluminate aggregates were discussed in detail, respectively.

Published
2021

24. Preferential removal of benzene, toluene, ethylbenzene, and xylene (BTEX) by persulfate in ethanol-containing aquifer materials

Author

Wei Meng, Yaping Jiang, Yaping Cheng, Yudao Chen, and Huan Wang

Subjects
chemistry.chemical_classification, Ethanol, Environmental remediation, Health, Toxicology and Mutagenesis, Xylene, Benzene, General Medicine, BTEX, Xylenes, Pollution, Ethylbenzene, chemistry.chemical_compound, Biodegradation, Environmental, Bioremediation, chemistry, In situ chemical oxidation, Environmental chemistry, Benzene Derivatives, Environmental Chemistry, Organic matter, Groundwater, Calcareous, Toluene
Abstract

The effective approaches to eliminate impacts of ethanol on the biodegradation of benzene, toluene, ethylbenzene, and xylene (BTEX) are concerned in the bioremediation of groundwater contaminated with ethanol-blended gasoline. In situ chemical oxidation (ISCO) is a common technique widely used for the remediation of contaminated groundwater. However, the selectivity of ISCO for BTEX and ethanol removal is poorly understood. Therefore, a batch experiment was performed with different aquifer materials, including calcareous soil, basalt soil, granite soil, dolomite, and sand. Gasoline was used to provide dissolved BTEX and ethanol reagent was used as additive to improve the quality of gasoline and to reduce the possibility of air pollution caused by gasoline. Persulfate (PS) was used as a chemical oxidant to oxidize organic contaminants. The target concentrations of BTEX and ethanol were 20 mg/L and 1000 mg/L, respectively. The results showed that ethanol could be preferentially degraded in the absence of PS and inhibit BTEX biodegradation. However, BTEX could be preferentially removed prior to ethanol in all aquifer materials used at ambient temperature, when PS was added at a PS/BTEX molar ratio of 150. Over 94% BTEX in sand, dolomite, and granite soil was preferentially removed with the first-order decay rate constants of 0.890–2.703 day−1 within the first ~ 10 days, followed by calcareous and basalt soil at the constants of 0.123–0.371 day−1. Ethanol could compete with BTEX for sulfate radical at the first-order decay rate constants of 0.005–0.060 day−1 for the first 25 days, which was slower than that of BTEX. The pH quickly decreased to 6.2 in calcareous soil. Rich organic matter in calcareous and basalt soil had an inhibition effect on BTEX oxidation by PS. The pH buffer in calcareous soil may imply the potential of PS oxidation combined with bioremediation in carbonate rock regions.

Published
2021

25. Plasma metabolomics for the assessment of the progression of non-small cell lung cancer

Author

Yingtian Zhang, Yaping Cheng, Liqiang Qin, Yuanliang Liu, Sijia Huang, Liya Dai, Jialong Tao, Jie Pan, Cunjin Su, and Yusong Zhang

Subjects
Cancer Research, Oncology, Clinical Biochemistry, Pathology and Forensic Medicine
Abstract

Objectives Non-small cell lung cancer (NSCLC) is a leading type of lung cancer with a high mortality rate worldwide. Although many procedures for the diagnosis and prognosis assessment of lung cancer exist, they are often laborious, expensive, and invasive. This study aimed to develop an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC–MS/MS)-based analysis method for the plasma biomarkers of NSCLC with the potential to indicate the stages and progression of this malignancy conveniently and reliably. Methods A total of 53 patients with NSCLC in early stages (I–III) and advanced stage (IV) were classified into the early and advanced groups based on the tumor node metastasis staging system. A comprehensive metabolomic analysis of plasma from patients with NSCLC was performed via UPLC–MS/MS. Principal component analysis and partial least squares–discriminant analysis were conducted for statistical analysis. Potential biomarkers were evaluated and screened through receiver operating characteristic analyses and correlation analysis. Main differential metabolic pathways were also identified by utilizing metaboanalyst. Results A total of 129 differential metabolites were detected in accordance with the criteria of VIP ≥ 1 and a P-value of ≤ 0.05. The receiver operating characteristic curves indicated that 11 of these metabolites have the potential to be promising markers of disease progression. Apparent correlated metabolites were also filtered out. Furthermore, the 11 most predominant metabolic pathways with alterations involved in NSCLC were identified. Conclusion Our study focused on the plasma metabolomic changes in patients with NSCLC. These changes may be used for the prediction of the stage and progression of NSCLC. Moreover, we discussed the metabolic pathways wherein the altered metabolites were mainly enriched.

Published
2022

27. Formation of ferrospinel layer at the corroded interface between Al 2 O 3 ‐spinel refractory and molten steel in RH refining ladle

Author

Yu Zhang, Yaowu Wei, Guangping Liu, Junli Xiao, Shaowei Zhang, Yuanyuan Li, Nan Li, Guangqiang Li, Yaping Cheng, and Junfeng Chen

Subjects
Ladle, Materials science, Metallurgy, Spinel, Materials Chemistry, Ceramics and Composites, Molten steel, engineering, engineering.material, Layer (electronics), Refractory (planetary science), Corrosion, Refining (metallurgy)
Published
2021

28. Ni/AntPhos-Catalyzed Stereoselective Asymmetric Intramolecular Reductive Coupling of N-1,6-Alkynones

Author

Yu Mu, Yaping Cheng, Guodu Liu, Wanjun Chen, Tao Zhang, and Wenqi Jia

Subjects
chemistry.chemical_compound, Allylic rearrangement, chemistry, Intramolecular force, Organic Chemistry, Enantioselective synthesis, Organic synthesis, Stereoselectivity, Triethylsilane, Combinatorial chemistry, Pyrrolidine, Catalysis
Abstract

An efficient nickel-catalyzed stereoselective asymmetric intramolecular reductive coupling of N-1,6-alkynones is reported. A P-chiral monophosphine ligand AntPhos was found to be a privileged catalyst for constructing versatile functionalized chiral pyrrolidine rings using triethylsilane as the reducing reagent. Concise synthesis of pyrrolidines with chiral tertiary allylic alcohols was achieved in high yields (99%), excellent stereoselectivity (>99:1 E/Z), and enantioselectivity (>99:1 er) with very broad substrate scope. Totally, thirty-five N-1,6-alkynones were synthesized and applied in this reaction successfully. This reaction can be scaled up to gram scale without loss of its enantioselectivity. Ligand effects and reaction mechanism are investigated in detail. While the developed asymmetric synthesis of pyrrolidine with chiral tertiary allylic alcohols is anticipated to find wider applications in organic synthesis and chemical biology, the discovered new reactions of N-1,6-alkynone with AntPhos using different catalyst systems would further expanded its new research fields and attract more detailed explorations in the future.

Published
2021

30. Efficient synthesis of tetrahydrofurans with chiral tertiary allylic alcohols catalyzed by Ni/P-chiral ligand DI-BIDIME

Author

Yu Mu, Guodu Liu, Yaping Cheng, Wenzhen Fu, Tao Zhang, Zuting Wei, and Wanjun Chen

Subjects
chemistry.chemical_compound, Allylic rearrangement, Reaction mechanism, chemistry, organic chemicals, Intramolecular force, Reagent, Chiral ligand, Stereoselectivity, Organic synthesis, Triethylsilane, Combinatorial chemistry, Catalysis
Abstract

Efficient nickel-catalyzed stereoselective asymmetric intramolecular reductive cyclization of O-alkynones is reported. A P-chiral bisphosphine ligand DI-BIDIME was found to be effective for constructing versatile functionalized chiral tetrahydrofuran rings using triethylsilane as the reducing reagent. Practical synthesis of tetrahydrofurans with chiral tertiary allylic alcohols was achieved in high yields (99%), which have excellent stereoselectivity (>99 : 1 E/Z) and enantioselectivity (>99 : 1 er) with a very broad substrate scope. A total of thirty-seven O-alkynones were synthesized and applied in this reaction successfully. This reaction can be scaled up to gram scale without loss of its enantioselectivity. The ligand effects and reaction mechanism are investigated in detail. Meanwhile, the developed method for tetrahydrofurans with chiral tertiary allylic alcohols enables the efficient synthesis of dehydroxycubebin and chiral dibenzocyclooctadiene skeletons, and is anticipated to find wider applications in organic synthesis and chemical biology; two new discovered reactions of O-alkynone with DI-BIDIME using different metal precursors would further expand new research fields, and attract more interesting explorations in the future.

Published
2021

31. Hydrothermal Synthesis of NiCo-layered Double Hydroxide Nanosheets Decorated on Biomass Carbon Skeleton for High Performance Supercapacitor

Author

Jia Chu, Jiafang Gong, Yaping Cheng, Fan Yang, Shanxin Xiong, and Xiaoqin Wang

Subjects
Supercapacitor, Materials science, Nanocomposite, Composite number, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, symbols.namesake, chemistry.chemical_compound, Chemical engineering, chemistry, Electrode, symbols, Hydrothermal synthesis, Hydroxide, Fourier transform infrared spectroscopy, 0210 nano-technology, Raman spectroscopy
Abstract

A facile hydrothermal strategy is adopted to synthesize the composite of NiCo-layered double hydroxide(NiCo-LDH) with biomass carbon as substrate for supercapacitor electrodes. The prepared NiCo@BC was characterized by means of X-ray diffraction(XRD), scanning electronic microscopy(SEM), Fourier transform infrared spectroscopy(FTIR) and Raman spectroscopy, and electrochemical tests. The SEM images demonstrated that numerous NiCo-LDH nanosheets directly grew on the surface of biomass carbon uniformly. Electrochemical tests indicated that the NiCo@BC electrode exhibited good capacitive behavior with a specific capacitance of 606.4 F/g at the current density of 0.5 A/g. In addition, the composite electrode showed excellent cyclic stability of 87.1% even after 1000 cycles. These results manifest that NiCo@BC nanocomposite is a promising candidate for the electrode material for future supercapacitor practical applications.

Published
2020

32. Suzuki Cross‐Coupling Reaction with Genetically Encoded Fluorosulfates for Fluorogenic Protein Labeling

Author

Weiwei Zhu, Yifan Da, Yaping Cheng, Xiaoqing Cai, Ying Han, Liping Zhu, Guoying Guo, Yani Zhou, Qian Zhao, Shuohan Wu, Xianxing Jiang, and Hongjiao Xu

Subjects
chemistry.chemical_classification, Aqueous medium, Biocompatibility, Sulfates, 010405 organic chemistry, Chemistry, Aryl halide, Green Fluorescent Proteins, Organic Chemistry, Water, General Chemistry, 010402 general chemistry, Protein labeling, Boronic Acids, 01 natural sciences, Combinatorial chemistry, Catalysis, Coupling reaction, 0104 chemical sciences, Green fluorescent protein, Posttranslational modification, Palladium, Fluorescent Dyes
Abstract

A palladium-catalyzed cross-coupling reaction with aryl halide functionalities has recently emerged as a valuable tool for protein modification. Herein, a new fluorogenic modification methodology for proteins, with genetically encoded fluorosulfate-l-tyrosine, which exhibits high efficiency and biocompatibility in bacterial cells as well as in aqueous medium, is described. Furthermore, the cross-coupling of 4-cyanophenylboronic acid on green fluorescent protein was shown to possess a unique fluorogenic property, which could open up the possibility of a responsive "off/on" switch with great potential to enable spectroscopic imaging of proteins with minimal background noise. Taken together, a convenient and efficient catalytic system has been developed that may provide broad utilities in protein visualization and live-cell imaging.

Published
2020

33. A microcosm study on persulfate oxidation combined with enhanced bioremediation to remove dissolved BTEX in gasoline-contaminated groundwater

Author

Yaping Cheng, Yuan Xia, Liuyue Li, Yudao Chen, and Yaping Jiang

Subjects
Environmental Engineering, Bioengineering, BTEX, Xylenes, 010501 environmental sciences, 01 natural sciences, Microbiology, Ethylbenzene, 03 medical and health sciences, chemistry.chemical_compound, Bioremediation, Nitrate, Benzene Derivatives, Environmental Chemistry, Benzene, Groundwater, 0105 earth and related environmental sciences, 0303 health sciences, Sulfates, 030306 microbiology, Xylene, Persulfate, Pollution, Toluene, Biodegradation, Environmental, chemistry, Environmental chemistry, Gasoline, Water Pollutants, Chemical
Abstract

The combination of persulfate (PS) oxidation with enhanced bioremediation (EBR) is a potential trend in remediating organic-contaminated groundwater. However, the impacts of PS on EBR presented in the transition zone between PS oxidation zone and EBR zone need further study. To better characterize the impacts and provide available indicators, PS oxidation and EBR with nitrate amended were performed through the microcosm experiments to remove dissolved benzene, toluene, ethylbenzene and xylene (denoted as BTEX) in gasoline-saturated groundwater. The results indicated that PS oxidation combined with EBR almost completely removed BTEX with the ratio of > 93% over the experiments, which is better than PS oxidation (54–97%) but still worse than EBR (100%). The removal velocities of BTEX in EBR, PS oxidation, and PS oxidation combined with EBR were 0.94, 0.1–0.16, and 0.1–0.54 mg/L/d, respectively. High concentration of PS, along with high-strength activation, made the pH decrease to 3.3–4.4 and the Eh increase to 141–203 mV, thus greatly inhibited microbial activities as well. In such circumstances, oxygen and nitrate could not be significantly used as electron acceptors by microbials. To reduce the impacts of PS oxidation on EBR, the PS/BTEX molar ratio of 1 may be appropriate in transition zone. The hydro-chemical indicators, including pH, Eh, and availability of electron acceptors such as oxygen and nitrate, could reflect the impacts of PS oxidation on bioprocesses. During in-situ chemical oxidation (ISCO), PS injection and PS activation by Fe2+ should be managed for decreasing the impacts on EBR, based on the PS/BTEX and PS/Fe2+ molar ratios.

Published
2020

34. Protein labeling approach to improve lysosomal targeting and efficacy of antibody–drug conjugates

Author

Yifan Da, Mingjia Yu, Xianxing Jiang, Ying Han, Xiaoqing Cai, Jiale Xiong, Yaping Cheng, Xin Wang, Guoying Guo, and Yan Li

Subjects
0301 basic medicine, Drug, Immunoconjugates, media_common.quotation_subject, Molecular Conformation, Antineoplastic Agents, Peptide, Endocytosis, Protein labeling, Biochemistry, Antibodies, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Humans, Amino Acid Sequence, Molecular Targeted Therapy, Physical and Theoretical Chemistry, Internalization, media_common, chemistry.chemical_classification, biology, Optical Imaging, Organic Chemistry, Clathrin, Cell biology, ErbB Receptors, Protein Transport, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, biology.protein, Antibody, Lysosomes, Peptides, Ligation, Protein Binding, Conjugate
Abstract

An anti-EGFR nanobody was labeled at the C-terminus with a lysosome-sorting NPGY (Asn-Pro-Gly-Tyr) motif via sortase-mediated ligation to enhance the engagement of the clathrin-mediated endocytosis. The synergistic effects of NPGY motif and nona-arginine peptide were found to induce robust internalization and lysosomal trafficking, which in turn improved anti-tumor activity of an antibody-drug conjugate.

Published
2020

37. Enantiopure, luminescent, cyclometalated Ir(III) complexes with N-heterocyclic carbene-naphthalimide chromophore: design, vibrational circular dichroism and TD-DFT calculations

Author

Antoine Groué, Eve Montier-Sorkine, Yaping Cheng, Marie Noelle Rager, Marion Jean, Nicolas Vanthuyne, Jeanne Crassous, Amalia C. Lopez, Alejandra Saavedra Moncada, Andrea Barbieri, Andrew L. Cooksy, Hani Amouri, Institut Parisien de Chimie Moléculaire (IPCM), Chimie Moléculaire de Paris Centre (FR 2769), Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL), Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC), Institut des Sciences Chimiques de Rennes (ISCR), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), San Diego State University (SDSU), Consiglio Nazionale delle Ricerche [Roma] (CNR), Sorbonne Universite-Campus Pierre et Marie Curie, CNRS Centre National de la Recherche Scientifique (CNRS) European Commission, Ile de France region Region Ile-de-France, NSF National Science Foundation (NSF) [OAC-2019194], National Research Council, Italy Consiglio Nazionale delle Ricerche (CNR) [CNR SAC.AD002.027], École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique de Rennes (IPR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Istituto per la Sintesi Organica e la Fotoreattività - ISOF (Bologne, Italie), Consiglio Nazionale delle Ricerche [Bologna] (CNR), and Sorbonne Université-Campus Pierre et Marie Curie, CNRS and Ile de France region for financial support of the 500 MHz NMR spectrometer to Chimie Paristech are gratefully acknowledged. A. L. C. acknowledges support from NSFOAC-2019194. A. B. acknowledges support from National Research Council, Italy, CNR SAC.AD002.027

Subjects
Inorganic Chemistry, Luminescent, Cyclometalated Ir(III) Complexes with N--Heterocyclic Carbene--Naphthalimide Chromophore: Design, [CHIM]Chemical Sciences, Enantiopure, Vibrational Circular Dichroism and TD--DFT Calculations
Abstract

International audience; A series of chiral cyclometalated iridium complexes of the type [Ir(C boolean AND N)(2)(C boolean AND C:)], {(C boolean AND N) = ppy (2); dfppy (3)} featuring a naphthalimide N-heterocyclic carbene ligand (C boolean AND C:) = (Naphthalimide-NHC) are described and fully characterized. The racemic complexes rac-2 and rac-3 were resolved via chiral column chromatography techniques into their corresponding enantiopure species Delta-2, Lambda-2, Delta-3, Lambda-3 as confirmed by their CD curves. This unique class of molecules containing organic and inorganic chromophores might be used as a platform to probe the stereochemical effect on the photophysical properties. Vibrational circular dichroism (VCD) was used as an important tool to assign successfully the stereochemistry of the enantiomers. TD-DFT calculations are also advanced to support the experimental studies and to rationalize the observed results.

Published
2022

38. Prussian Blue and Carbon-Dot Hybrids for Enhanced Electrochromic Performance

Author

Yaping Cheng, Jia Chu, Fan Yang, Xue Li, Shanxin Xiong, and Zhao Zhang

Subjects
hydrothermal, Technology, Materials science, Optical contrast, Scanning electron microscope, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Hydrothermal circulation, Article, symbols.namesake, chemistry.chemical_compound, General Materials Science, Thin film, electrochromic, carbon dot, Carbon dot, Prussian blue, Microscopy, QC120-168.85, QH201-278.5, 021001 nanoscience & nanotechnology, Engineering (General). Civil engineering (General), 0104 chemical sciences, TK1-9971, Chemical engineering, chemistry, Descriptive and experimental mechanics, Electrochromism, symbols, Electrical engineering. Electronics. Nuclear engineering, TA1-2040, 0210 nano-technology, Raman spectroscopy
Abstract

In this study, Prussian blue@Carbon-dot (PB@C-dot) hybrids have been developed by one-step hydrothermal method. The incorporation of C-dots into Prussian blue thin film as a way of improving its electrochromic performance was investigated. The structure of the PB@C-dot hybrid was characterized through X-ray diffraction, Raman spectroscopy and scanning electron microscopy. The electrochromic properties showed that incorporation of 10 mL C-dots into the film showed higher optical contrast of 1.6 and superior coloration/bleaching response of 10 and 3 s. It is proposed that the C-dots component used in the construction of the PB@C-dot hybrid plays a key role to achieve superior electrochromic performance.

Published
2021

39. A CDR-based approach to generate covalent inhibitory antibody for human rhinovirus protease

Author

Qian Zhao, Xiaoqing Cai, Huayao Chen, Yaping Cheng, Guoying Guo, Jingyao Xu, Xianxing Jiang, Yani Zhou, Yifan Da, Jinghong Liu, Yimin Chen, Jingyuan Wu, and Ying Han

Subjects
Models, Molecular, Rhinovirus, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Cysteine Proteinase Inhibitors, 01 natural sciences, Biochemistry, Antibodies, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Molecular Biology, chemistry.chemical_classification, Protease, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Drug discovery, Organic Chemistry, Mutagenesis, Rational design, 3C Viral Proteases, Small molecule, Complementarity Determining Regions, 0104 chemical sciences, Amino acid, 010404 medicinal & biomolecular chemistry, chemistry, Covalent bond, biology.protein, Molecular Medicine, Antibody
Abstract

Covalent target modulation with small molecules has been emerging as a promising strategy for drug discovery. However, covalent inhibitory antibody remains unexplored due to the lack of efficient strategies to engineer antibody with desired bioactivity. Herein, we developed an intracellular selection method to generate covalent inhibitory antibody against human rhinovirus 14 (HRV14) 3C protease through unnatural amino acid mutagenesis along the heavy chain complementarity-determining region 3 (CDR-H3). A library of antibody mutants was thus constructed and screened in vivo through co-expression with the target protease. Using this screening strategy, six covalent antibodies with proximity-enabled bioactivity were identified, which were shown to covalently target HRV14-3C protease with high inhibitory potency and exquisite selectivity. Compared to structure-based rational design, this library-based screening method provides a simple and efficient way for the discovery and engineering of covalent antibody for enzyme inhibition.

Published
2021

41. Calibration strategy of the JUNO experiment

Author

Andrea Barresi, Muhammad Usman Rajput, Chengzhuo Yuan, Demin Li, Cédric Huss, Jie Zhao, Xianghui Yu, W. H. Huang, Feng Gao, Sen Qian, Patrick Kinz, Miao He, Axel Müller, Davit Mayilyan, Utane Sawangwit, Jacques Wurtz, Wenju Huo, Hang Hu, Guanghua Gong, G. Andronico, Giuseppe Verde, Si Ma, Livia Ludhova, Xiaoyu Yang, Lucia Votano, Waqas Muhammad, Oleg Smirnov, Jie Yang, Zhe Ning, Y. X. Zhang, Zhuang Shao, Jun Wang, Martin Dvorak, Hao Liang, Nikolay Morozov, Ara Ioannisian, Qingmin Zhang, Ezio Previtali, Barbara Ricci, Ints Mednieks, Wuming Luo, Rossella Caruso, Diru Wu, Alexander Studenikin, Sadia Marium, Jingbo Zhang, M. Settimo, A. Popov, Enrico Bernieri, Xiaowei Liu, Yumei Zhang, Anut Sangka, Feipeng Ning, F. Z. Qi, Simon Blyth, Anatael Cabrera, Antonio Insolia, Donglian Xu, Amir N. Khan, Minghao Gu, Daniel Liebau, Shouyang Hu, Thilo Birkenfeld, Mengyun Guan, Gérard Claverie, Xin Mao, Xingtao Huang, Guoqing Zhang, Markus Robens, Jari Joutsenvaara, Zhibing Li, Can Fang, Nuanwan Sanguansak, Andrey Formozov, Ugur Yegin, Yuekun Heng, Xiaohui Qian, Riccardo Bruno, Zafar Yasin, Selma Conforti Di Lorenzo, Weidong Li, Xiaonan Li, Cédric Schwab, Yuguang Xie, Narumon Suwonjandee, Michael Wurm, Teerapat Payupol, Andrea Serafini, Chunhao Huang, Fangliang Wu, Haoqi Lu, Di Jiang, Salvatore Costa, Yue Meng, Y. Sun, S. Dusini, Mathieu Roche, Stefano Maria Mari, S. Parmeggiano, N. Raper, M. A. Szelezniak, W. J. Wu, Jingbin Lu, Heike Enzmann, Nan Li, Zhonghua Qin, Min Liu, Q. J. Li, Tobias Heinz, Frédéric Druillole, Qun Wu, Anbo Yang, Hongjuan Liu, Sukit Limpijumnong, Peihuai Yi, Cecilia Landini, Jonathan Miller, Yu Xu, Agnese Martini, Vito Antonelli, A. Bolshakova, Alexandre Göttel, X. L. Ji, Yuanqing Wang, Haonan Gan, Lei Yang, Sebastiano Aiello, Leonidas Kalousis, Andre Zambanini, R. T. Lei, Stefan van Waasen, Dmitry Selivanov, Khanchai Khosonthongkee, Yanke Cai, F. Yermia, Yuman Wang, Rong Zhao, Jian Wang, E. Meroni, Filippo Marini, Narine Kazarian, Y. F. Wang, Shanfeng Li, Q. An, Alessandra Re, Chung-Hsiang Wang, Agnese Giaz, Tingxuan Zeng, Guihong Huang, Andrej Babic, Fabio Mantovani, Fang Liu, Richard Ford, Zhe Wang, Christian Grewing, Antonio Bergnoli, Warintorn Sreethawong, Georgy Donchenko, S. Krokhaleva, Mengzhao Li, Rupert Leitner, Monica Sisti, Domizia Orestano, Mario Buscemi, Paolo Montini, Marco Grassi, Zeyuan Yu, Tobias Lachenmaier, Jianrun Hu, Victor Lebrin, Angel Abusleme, Boxiang Yu, Tao Li, Maciej Slupecki, Boonrucksar Soonthornthum, Catia Clementi, Marco Giammarchi, Francesco Manzali, B. Z. Hu, Virginia Strati, Alexey Krasnoperov, Zhang Chen, Hua Zheng, P. Saggese, Minshan Zheng, Xiaolu Ji, Gisele Martin-Chassard, Matthias Raphael Stock, Pablo Walker, Jose Busto, Agustin Campeny, Burin Asavapibhop, Yinhong Zhang, S. B. Liu, Vitaly Shutov, Barbara Clerbaux, Peng Zhang, Zhengyun You, Yayun Ding, Shubin Liu, Ayut Limphirat, S. Dmitrievsky, Siyu Jian, S. Sanfilippo, Cristina Tuve, Shoukang Qiu, Shifeng Sun, Jie Ren, Sébastien Leblanc, Po-An Chen, Xubo Ma, Safeer Hussain, Guangpeng An, Nicomede Pelliccia, Yuhang Guo, Shan Zeng, Konstantin A. Kouzakov, Shaojing Hou, Jing Xu, X. H. Guo, Feiyang Zhang, Dongqin Zheng, Ilya Butorov, Maria Gul, Kunyu Wang, Claudio Lombardo, Zhi Deng, Zhiyan Cai, Yu Gu, Yufei Xi, K. Loo, R. Brugnera, Shu Luo, Jiaheng Zou, Ran Han, Giancarlo Troni, M. H. Ye, Xiaoxu Lu, Fengjiao Luo, H. D. Liu, Haitao Li, Fei Li, Julanan Songwadhana, Xiaomei Zhang, Fengpeng An, X. D. Ruan, Chunxu Yu, Vadim Vedin, Mauro Mezzetto, Jiaqi Li, Caren Hagner, Shu Zhang, Wander Baldini, Yangheng Zheng, Antonio Budano, Michele Montuschi, Zheng Wang, Qin Liu, Pierre-Alexandre Petitjean, Xuefeng Ding, H. R. Pan, Lukas Fajt, Jingyan Shi, David Meyhöfer, Fanrong Xu, Marco Bellato, Zhenyu Zhang, S. J. Zhao, Clément Bordereau, Yan Zhang, Bayarto Lubsandorzhiev, Guang Luo, Benda Xu, Xiangyue Wang, Christophe De La Taille, Miao Yu, Christian Roth, Nina Parkalian, Andrea Fabbri, Fausto Ortica, João Pedro Athayde Marcondes de André, Y. Wang, Liangjian Wen, S. X. Du, Jian Tang, Frederic Lefevre, Tao Hu, Vasily Gromov, Guofu Cao, Liang Zhan, E. Doroshkevich, Steven Chan-Fai Wong, Amélie Fournier, Apimook Watcharangkool, Jinchang Liu, Qian Liu, Yongbo Huang, Bayu Dirgantara, Chiara Sirignano, Qiumei Ma, Yi Wang, A. Sadovsky, Xichao Ruan, Caishen Wang, G. Settanta, Flavio Dal Corso, Beatrice Jelmini, Guillaume Vanroyen, Baojun Yan, Ruhui Li, Mikhail Smirnov, Huan Yang, Z. Wu, Xiao Cai, Yun Chang, Meng Wang, Yufeng Li, Tianchi Zhao, K. L. Jen, Li-Cheng Feng, Guey-Lin Lin, Shuxiang Lu, Massimiliano Nastasi, Thomas Adam, Rizwan Ahmed, David Blum, Marco Fargetta, Didier Auguste, Weiguo Li, Jian Fang, Patrick Hellmuth, Muhammad Akram, Hui Liu, Tomas Tmej, G. X. Sun, Fengyi Zhao, Christian Wysotzki, Wladyslaw Henryk Trzaska, Achim Stahl, Sylvie Blin, Yin Xu, Alexander Tietzsch, Fedor Šimkovic, Haiping Peng, Ziping Ye, Baobiao Yue, A. Sotnikov, Aldo Romani, Anna Chuvashova, Noman Zafar, Tatiana Antoshkina, Wanlei Guo, C. Jollet, Christoph Genster, Sultim Lubsandorzhiev, Y. K. Sun, Xiangwei Yin, Xiaoping Jing, H. Steiger, Muhammad Sohaib Hassan, Cristina Martellini, Wei Wang, B. Viaud, Igor Nemchenok, Zhijian Zhang, Fatma Sawy, Xiaofei Gu, Alexander Olshevskiy, Liang Zong, Pavithra Muralidharan, Xiaomei Li, Alexandr Selyunin, Yu Chen, Jochen Steinmann, Qiang Tang, Daojin Hong, Daniele Corti, Yatian Pei, S. Zhang, Denis Korablev, Yi Chen, Dominique Breton, Franco Giuliani, F. Li, Augusto Brigatti, Artem Chukanov, Nikolaos Vassilopoulos, Jiaxuan Ye, Yi-Wen Chen, K. Treskov, Michael Karagounis, Haiqiong Zhang, Jiang Zhu, Nunzio Giudice, Zongyi Wang, H. L. Zhuang, Marco Aurelio Diaz, Nikolay Kutovskiy, Shakeel Ahmad, Narongkiat Rodphai, Yifan Yang, Huihui Jia, Juan Pedro Ochoa-Ricoux, Jin Li, Hongtao Liu, Andrey Sidorenkov, Qichun Feng, Jiawen Zhang, T. Enqvist, Ruyi Jin, J. J. Ling, Arseniy Rybnikov, Lino Miramonti, Yi Li, Luis Felipe Piñeres Rico, Ziyuan Li, Ziyi Yuan, A. Lokhov, Jie Cheng, Rafael Herrera, Jiaqi Hui, Wathan Pratumwan, En Wang, Konstantin Schweizer, A. Kruth, Tobias Sterr, Shengxin Lin, Anna Fatkina, Fabrizio Petrucci, Mathieu Bongrand, Olivia Dalager, Alessandro Paoloni, Philipp Kampmann, Roberto Isocrate, Jianmeng Dong, Weirong Zhong, Yiyu Zhang, Saroj Rujirawat, Giuseppe Salamanna, Maxim Vialkov, Abdel Rebii, Mengjiao Xiao, Jing Zhou, P. Chimenti, Jingjing Liang, Yuanyuan Zhang, Pingping Chen, Igor Tkachev, A. Cammi, Oliver Pilarczyk, Vit Vorobel, Zhimin Wang, Honghao Zhang, Zhenxiong Yuan, Xiang Zhou, Damien Dornic, Jie Zhang, Zhangquan Xie, Yaping Cheng, Ying Yuan, Maxim Gonchar, Wei Wei, Zhuojun Hu, Ivano Lippi, Xilei Sun, Shaomin Chen, Jun Cao, Li Zhou, Ruiguang Wang, Nikolay Anfimov, Andrea Triossi, Runxuan Liu, Xinglong Li, Waseem Khan, Pasi Kuusiniemi, Xi Wang, Salvatore Monforte, Meihang Xu, Eric Baussan, Haifeng Yao, Xuantong Zhang, Yang Han, Pascal Poussot, Dongmei Xia, Jacky Schuler, Hao Qiao, Hu Liu, Henning Rebber, Dmitry V. Naumov, Luca Stanco, Paul Hackspacher, Y. K. Hor, Lei Fan, Ziyan Deng, Lei Huo, Ondrej Sramek, K. J. Li, Jianglai Liu, Lu Wang, Paolo Lombardi, Marcos Dracos, B. Roskovec, Taras Rezinko, Quan Tang, Jiawei Deng, Jason Leung, Xiao Tang, Junji Jia, Huiling Li, Nunzio Guardone, Chuanya Cao, Diana Navas-Nicolas, A. Meregaglia, Zhi-zhong Xing, V. Fekete, Jilei Xu, W. Wang, Siguang Wang, Yupeng Yan, Hao Cai, Christopher Wiebusch, Y. B. Hsiung, Z. V. Krumshteyn, Sirichok Jungthawan, Thiago Sogo-Bezerra, Yury Malyshkin, S. Li, Dmitry Fedoseev, Tao Lin, Chuan Lu, J. F. Chang, Davide Chiesa, Changgen Yang, A. Garfagnini, F. Perrot, Wilfried Depnering, Xiaoyan Ma, Yadong Wei, M. Wang, O. Gorchakov, Yajun Mao, Anguo Peng, C. Cerna, Wei He, Lothar Oberauer, Konstantin Stankevich, Yuri Gornushkin, Donghua Fan, Cong Guo, Dušan Štefánik, Ming Qi, Lianghong Wei, Jihane Maalmi, E. Naumova, Jaruchit Siripak, Tadeas Dohnal, Julia Sawatzki, Hongbang Liu, X. R. Chen, Bjoern Wonsak, Vladimir Lyashuk, Johannes van den Boom, Qinhua Huang, Jingyuan Guo, Yuda Zeng, Shulin Liu, Tao Zhang, Guo-Li Wang, Hui Gong, Michaela Schever, Jun Hu, K. J. Zhu, P. W. Luo, Shun Zhou, Bin Ren, Nan Zhou, Yan Liu, Li Kang, Junguang Lu, Gioacchino Ranucci, Chiye Yu, Cheng Xu, Hongzhao Yu, Hanxiong Huang, Xiongbo Yan, Sai-Juan Chen, C. Volpe, Hiroshi Nunokawa, Yanchu Wang, Vladislav Sharov, Xiaoshan Jiang, Abusleme, A, Adam, T, Ahmad, S, Ahmed, R, Aiello, S, Akram, M, An, F, An, G, An, Q, Andronico, G, Anfimov, N, Antonelli, V, Antoshkina, T, Asavapibhop, B, de Andre, J, Auguste, D, Babic, A, Baldini, W, Barresi, A, Baussan, E, Bellato, M, Bergnoli, A, Bernieri, E, Birkenfeld, T, Blin, S, Blum, D, Blyth, S, Bolshakova, A, Bongrand, M, Bordereau, C, Breton, D, Brigatti, A, Brugnera, R, Bruno, R, Budano, A, Buscemi, M, Busto, J, Butorov, I, Cabrera, A, Cai, H, Cai, X, Cai, Y, Cai, Z, Cammi, A, Campeny, A, Cao, C, Cao, G, Cao, J, Caruso, R, Cerna, C, Chang, J, Chang, Y, Chen, P, Chen, S, Chen, X, Chen, Y, Chen, Z, Cheng, J, Cheng, Y, Chiesa, D, Chimenti, P, Chukanov, A, Chuvashova, A, Claverie, G, Clementi, C, Clerbaux, B, Lorenzo, S, Corti, D, Costa, S, Corso, F, Dalager, O, Taille, C, Deng, J, Deng, Z, Depnering, W, Diaz, M, Ding, X, Ding, Y, Dirgantara, B, Dmitrievsky, S, Dohnal, T, Donchenko, G, Dong, J, Dornic, D, Doroshkevich, E, Dracos, M, Druillole, F, Du, S, Dusini, S, Dvorak, M, Enqvist, T, Enzmann, H, Fabbri, A, Fajt, L, Fan, D, Fan, L, Fang, C, Fang, J, Fargetta, M, Fatkina, A, Fedoseev, D, Fekete, V, Feng, L, Feng, Q, Ford, R, Formozov, A, Fournier, A, Gan, H, Gao, F, Garfagnini, A, Gottel, A, Genster, C, Giammarchi, M, Giaz, A, Giudice, N, Giuliani, F, Gonchar, M, Gong, G, Gong, H, Gorchakov, O, Gornushkin, Y, Grassi, M, Grewing, C, Gromov, V, Gu, M, Gu, X, Gu, Y, Guan, M, Guardone, N, Gul, M, Guo, C, Guo, J, Guo, W, Guo, X, Guo, Y, Hackspacher, P, Hagner, C, Han, R, Han, Y, Hassan, M, He, M, He, W, Heinz, T, Hellmuth, P, Heng, Y, Herrera, R, Hong, D, Hor, Y, Hou, S, Hsiung, Y, Hu, B, Hu, H, Hu, J, Hu, S, Hu, T, Hu, Z, Huang, C, Huang, G, Huang, H, Huang, Q, Huang, W, Huang, X, Huang, Y, Hui, J, Huo, L, Huo, W, Huss, C, Hussain, S, Insolia, A, Ioannisian, A, Isocrate, R, Jelmini, B, Jen, K, Ji, X, Jia, H, Jia, J, Jian, S, Jiang, D, Jiang, X, Jin, R, Jing, X, Jollet, C, Joutsenvaara, J, Jungthawan, S, Kalousis, L, Kampmann, P, Kang, L, Karagounis, M, Kazarian, N, Khan, A, Khan, W, Khosonthongkee, K, Kinz, P, Korablev, D, Kouzakov, K, Krasnoperov, A, Krokhaleva, S, Krumshteyn, Z, Kruth, A, Kutovskiy, N, Kuusiniemi, P, Lachenmaier, T, Landini, C, Leblanc, S, Lebrin, V, Lefevre, F, Lei, R, Leitner, R, Leung, J, Li, D, Li, F, Li, H, Li, J, Li, K, Li, M, Li, N, Li, Q, Li, R, Li, S, Li, T, Li, W, Li, X, Li, Y, Li, Z, Liang, H, Liang, J, Liebau, D, Limphirat, A, Limpijumnong, S, Lin, G, Lin, S, Lin, T, Ling, J, Lippi, I, Liu, F, Liu, H, Liu, J, Liu, M, Liu, Q, Liu, R, Liu, S, Liu, X, Liu, Y, Lokhov, A, Lombardi, P, Lombardo, C, Loo, K, Lu, C, Lu, H, Lu, J, Lu, S, Lu, X, Lubsandorzhiev, B, Lubsandorzhiev, S, Ludhova, L, Luo, F, Luo, G, Luo, P, Luo, S, Luo, W, Lyashuk, V, Ma, Q, Ma, S, Ma, X, Maalmi, J, Malyshkin, Y, Mantovani, F, Manzali, F, Mao, X, Mao, Y, Mari, S, Marini, F, Marium, S, Martellini, C, Martin-Chassard, G, Martini, A, Mayilyan, D, Muller, A, Mednieks, I, Meng, Y, Meregaglia, A, Meroni, E, Meyhofer, D, Mezzetto, M, Miller, J, Miramonti, L, Monforte, S, Montini, P, Montuschi, M, Morozov, N, Muhammad, W, Muralidharan, P, Nastasi, M, Naumov, D, Naumova, E, Navas-Nicolas, D, Nemchenok, I, Ning, F, Ning, Z, Nunokawa, H, Oberauer, L, Ochoa-Ricoux, J, Olshevskiy, A, Orestano, D, Ortica, F, Pan, H, Paoloni, A, Parkalian, N, Parmeggiano, S, Payupol, T, Pei, Y, Pelliccia, N, Peng, A, Peng, H, Perrot, F, Petitjean, P, Petrucci, F, Rico, L, Pilarczyk, O, Popov, A, Poussot, P, Pratumwan, W, Previtali, E, Qi, F, Qi, M, Qian, S, Qian, X, Qiao, H, Qin, Z, Qiu, S, Rajput, M, Ranucci, G, Raper, N, Re, A, Rebber, H, Rebii, A, Ren, B, Ren, J, Rezinko, T, Ricci, B, Robens, M, Roche, M, Rodphai, N, Romani, A, Roskovec, B, Roth, C, Ruan, X, Rujirawat, S, Rybnikov, A, Sadovsky, A, Saggese, P, Salamanna, G, Sanfilippo, S, Sangka, A, Sanguansak, N, Sawangwit, U, Sawatzki, J, Sawy, F, Schever, M, Schuler, J, Schwab, C, Schweizer, K, Selivanov, D, Selyunin, A, Serafini, A, Settanta, G, Settimo, M, Shao, Z, Sharov, V, Shi, J, Shutov, V, Sidorenkov, A, Simkovic, F, Sirignano, C, Siripak, J, Sisti, M, Slupecki, M, Smirnov, M, Smirnov, O, Sogo-Bezerra, T, Songwadhana, J, Soonthornthum, B, Sotnikov, A, Sramek, O, Sreethawong, W, Stahl, A, Stanco, L, Stankevich, K, Stefanik, D, Steiger, H, Steinmann, J, Sterr, T, Stock, M, Strati, V, Studenikin, A, Sun, G, Sun, S, Sun, X, Sun, Y, Suwonjandee, N, Szelezniak, M, Tang, J, Tang, Q, Tang, X, Tietzsch, A, Tkachev, I, Tmej, T, Treskov, K, Triossi, A, Troni, G, Trzaska, W, Tuve, C, van Waasen, S, van den Boom, J, Vanroyen, G, Vassilopoulos, N, Vedin, V, Verde, G, Vialkov, M, Viaud, B, Volpe, C, Vorobel, V, Votano, L, Walker, P, Wang, C, Wang, E, Wang, G, Wang, J, Wang, K, Wang, L, Wang, M, Wang, R, Wang, S, Wang, W, Wang, X, Wang, Y, Wang, Z, Watcharangkool, A, Wei, L, Wei, W, Wei, Y, Wen, L, Wiebusch, C, Wong, S, Wonsak, B, Wu, D, Wu, F, Wu, Q, Wu, W, Wu, Z, Wurm, M, Wurtz, J, Wysotzki, C, Xi, Y, Xia, D, Xiao, M, Xie, Y, Xie, Z, Xing, Z, Xu, B, Xu, C, Xu, D, Xu, F, Xu, J, Xu, M, Xu, Y, Yan, B, Yan, X, Yan, Y, Yang, A, Yang, C, Yang, H, Yang, J, Yang, L, Yang, X, Yang, Y, Yao, H, Yasin, Z, Ye, J, Ye, M, Ye, Z, Yegin, U, Yermia, F, Yi, P, Yin, X, You, Z, Yu, B, Yu, C, Yu, H, Yu, M, Yu, X, Yu, Z, Yuan, C, Yuan, Y, Yuan, Z, Yue, B, Zafar, N, Zambanini, A, Zeng, S, Zeng, T, Zeng, Y, Zhan, L, Zhang, F, Zhang, G, Zhang, H, Zhang, J, Zhang, P, Zhang, Q, Zhang, S, Zhang, T, Zhang, X, Zhang, Y, Zhang, Z, Zhao, F, Zhao, J, Zhao, R, Zhao, S, Zhao, T, Zheng, D, Zheng, H, Zheng, M, Zheng, Y, Zhong, W, Zhou, J, Zhou, L, Zhou, N, Zhou, S, Zhou, X, Zhu, J, Zhu, K, Zhuang, H, Zong, L, Zou, J, Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), JUNO, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Abusleme A., Adam T., Ahmad S., Ahmed R., Aiello S., Akram M., An F., An G., An Q., Andronico G., Anfimov N., Antonelli V., Antoshkina T., Asavapibhop B., de Andre J.P.A.M., Auguste D., Babic A., Baldini W., Barresi A., Baussan E., Bellato M., Bergnoli A., Bernieri E., Birkenfeld T., Blin S., Blum D., Blyth S., Bolshakova A., Bongrand M., Bordereau C., Breton D., Brigatti A., Brugnera R., Bruno R., Budano A., Buscemi M., Busto J., Butorov I., Cabrera A., Cai H., Cai X., Cai Y., Cai Z., Cammi A., Campeny A., Cao C., Cao G., Cao J., Caruso R., Cerna C., Chang J., Chang Y., Chen P., Chen P.-A., Chen S., Chen X., Chen Y.-W., Chen Y., Chen Z., Cheng J., Cheng Y., Chiesa D., Chimenti P., Chukanov A., Chuvashova A., Claverie G., Clementi C., Clerbaux B., Lorenzo S.C.D., Corti D., Costa S., Corso F.D., Dalager O., Taille C.D.L., Deng J., Deng Z., Depnering W., Diaz M., Ding X., Ding Y., Dirgantara B., Dmitrievsky S., Dohnal T., Donchenko G., Dong J., Dornic D., Doroshkevich E., Dracos M., Druillole F., Du S., Dusini S., Dvorak M., Enqvist T., Enzmann H., Fabbri A., Fajt L., Fan D., Fan L., Fang C., Fang J., Fargetta M., Fatkina A., Fedoseev D., Fekete V., Feng L.-C., Feng Q., Ford R., Formozov A., Fournier A., Gan H., Gao F., Garfagnini A., Gottel A., Genster C., Giammarchi M., Giaz A., Giudice N., Giuliani F., Gonchar M., Gong G., Gong H., Gorchakov O., Gornushkin Y., Grassi M., Grewing C., Gromov V., Gu M., Gu X., Gu Y., Guan M., Guardone N., Gul M., Guo C., Guo J., Guo W., Guo X., Guo Y., Hackspacher P., Hagner C., Han R., Han Y., Hassan M., He M., He W., Heinz T., Hellmuth P., Heng Y., Herrera R., Hong D., Hor Y., Hou S., Hsiung Y., Hu B.-Z., Hu H., Hu J., Hu S., Hu T., Hu Z., Huang C., Huang G., Huang H., Huang Q., Huang W., Huang X., Huang Y., Hui J., Huo L., Huo W., Huss C., Hussain S., Insolia A., Ioannisian A., Isocrate R., Jelmini B., Jen K.-L., Ji X., Jia H., Jia J., Jian S., Jiang D., Jiang X., Jin R., Jing X., Jollet C., Joutsenvaara J., Jungthawan S., Kalousis L., Kampmann P., Kang L., Karagounis M., Kazarian N., Khan A., Khan W., Khosonthongkee K., Kinz P., Korablev D., Kouzakov K., Krasnoperov A., Krokhaleva S., Krumshteyn Z., Kruth A., Kutovskiy N., Kuusiniemi P., Lachenmaier T., Landini C., Leblanc S., Lebrin V., Lefevre F., Lei R., Leitner R., Leung J., Li D., Li F., Li H., Li J., Li K., Li M., Li N., Li Q., Li R., Li S., Li T., Li W., Li X., Li Y., Li Z., Liang H., Liang J., Liebau D., Limphirat A., Limpijumnong S., Lin G.-L., Lin S., Lin T., Ling J., Lippi I., Liu F., Liu H., Liu J., Liu M., Liu Q., Liu R., Liu S., Liu X., Liu Y., Lokhov A., Lombardi P., Lombardo C., Loo K., Lu C., Lu H., Lu J., Lu S., Lu X., Lubsandorzhiev B., Lubsandorzhiev S., Ludhova L., Luo F., Luo G., Luo P., Luo S., Luo W., Lyashuk V., Ma Q., Ma S., Ma X., Maalmi J., Malyshkin Y., Mantovani F., Manzali F., Mao X., Mao Y., Mari S.M., Marini F., Marium S., Martellini C., Martin-Chassard G., Martini A., Mayilyan D., Muller A., Mednieks I., Meng Y., Meregaglia A., Meroni E., Meyhofer D., Mezzetto M., Miller J., Miramonti L., Monforte S., Montini P., Montuschi M., Morozov N., Muhammad W., Muralidharan P., Nastasi M., Naumov D.V., Naumova E., Navas-Nicolas D., Nemchenok I., Ning F., Ning Z., Nunokawa H., Oberauer L., Ochoa-Ricoux J.P., Olshevskiy A., Orestano D., Ortica F., Pan H.-R., Paoloni A., Parkalian N., Parmeggiano S., Payupol T., Pei Y., Pelliccia N., Peng A., Peng H., Perrot F., Petitjean P.-A., Petrucci F., Rico L.F.P., Pilarczyk O., Popov A., Poussot P., Pratumwan W., Previtali E., Qi F., Qi M., Qian S., Qian X., Qiao H., Qin Z., Qiu S., Rajput M., Ranucci G., Raper N., Re A., Rebber H., Rebii A., Ren B., Ren J., Rezinko T., Ricci B., Robens M., Roche M., Rodphai N., Romani A., Roskovec B., Roth C., Ruan X., Rujirawat S., Rybnikov A., Sadovsky A., Saggese P., Salamanna G., Sanfilippo S., Sangka A., Sanguansak N., Sawangwit U., Sawatzki J., Sawy F., Schever M., Schuler J., Schwab C., Schweizer K., Selivanov D., Selyunin A., Serafini A., Settanta G., Settimo M., Shao Z., Sharov V., Shi J., Shutov V., Sidorenkov A., Simkovic F., Sirignano C., Siripak J., Sisti M., Slupecki M., Smirnov M., Smirnov O., Sogo-Bezerra T., Songwadhana J., Soonthornthum B., Sotnikov A., Sramek O., Sreethawong W., Stahl A., Stanco L., Stankevich K., Stefanik D., Steiger H., Steinmann J., Sterr T., Stock M.R., Strati V., Studenikin A., Sun G., Sun S., Sun X., Sun Y., Suwonjandee N., Szelezniak M., Tang J., Tang Q., Tang X., Tietzsch A., Tkachev I., Tmej T., Treskov K., Triossi A., Troni G., Trzaska W., Tuve C., van Waasen S., van den Boom J., Vanroyen G., Vassilopoulos N., Vedin V., Verde G., Vialkov M., Viaud B., Volpe C., Vorobel V., Votano L., Walker P., Wang C., Wang C.-H., Wang E., Wang G., Wang J., Wang K., Wang L., Wang M., Wang R., Wang S., Wang W., Wang X., Wang Y., Wang Z., Watcharangkool A., Wei L., Wei W., Wei Y., Wen L., Wiebusch C., Wong S.C.-F., Wonsak B., Wu D., Wu F., Wu Q., Wu W., Wu Z., Wurm M., Wurtz J., Wysotzki C., Xi Y., Xia D., Xiao M., Xie Y., Xie Z., Xing Z., Xu B., Xu C., Xu D., Xu F., Xu J., Xu M., Xu Y., Yan B., Yan X., Yan Y., Yang A., Yang C., Yang H., Yang J., Yang L., Yang X., Yang Y., Yao H., Yasin Z., Ye J., Ye M., Ye Z., Yegin U., Yermia F., Yi P., Yin X., You Z., Yu B., Yu C., Yu H., Yu M., Yu X., Yu Z., Yuan C., Yuan Y., Yuan Z., Yue B., Zafar N., Zambanini A., Zeng S., Zeng T., Zeng Y., Zhan L., Zhang F., Zhang G., Zhang H., Zhang J., Zhang P., Zhang Q., Zhang S., Zhang T., Zhang X., Zhang Y., Zhang Z., Zhao F., Zhao J., Zhao R., Zhao S., Zhao T., Zheng D., Zheng H., Zheng M., Zheng Y., Zhong W., Zhou J., Zhou L., Zhou N., Zhou S., Zhou X., Zhu J., Zhu K., Zhuang H., Zong L., Zou J., Abusleme, A., Adam, T., Ahmad, S., Ahmed, R., Aiello, S., Akram, M., An, F., An, G., An, Q., Andronico, G., Anfimov, N., Antonelli, V., Antoshkina, T., Asavapibhop, B., de Andre, J. P. A. M., Auguste, D., Babic, A., Baldini, W., Barresi, A., Baussan, E., Bellato, M., Bergnoli, A., Bernieri, E., Birkenfeld, T., Blin, S., Blum, D., Blyth, S., Bolshakova, A., Bongrand, M., Bordereau, C., Breton, D., Brigatti, A., Brugnera, R., Bruno, R., Budano, A., Buscemi, M., Busto, J., Butorov, I., Cabrera, A., Cai, H., Cai, X., Cai, Y., Cai, Z., Cammi, A., Campeny, A., Cao, C., Cao, G., Cao, J., Caruso, R., Cerna, C., Chang, J., Chang, Y., Chen, P., Chen, P. -A., Chen, S., Chen, X., Chen, Y. -W., Chen, Y., Chen, Z., Cheng, J., Cheng, Y., Chiesa, D., Chimenti, P., Chukanov, A., Chuvashova, A., Claverie, G., Clementi, C., Clerbaux, B., Lorenzo, S. C. D., Corti, D., Costa, S., Corso, F. D., Dalager, O., Taille, C. D. L., Deng, J., Deng, Z., Depnering, W., Diaz, M., Ding, X., Ding, Y., Dirgantara, B., Dmitrievsky, S., Dohnal, T., Donchenko, G., Dong, J., Dornic, D., Doroshkevich, E., Dracos, M., Druillole, F., Du, S., Dusini, S., Dvorak, M., Enqvist, T., Enzmann, H., Fabbri, A., Fajt, L., Fan, D., Fan, L., Fang, C., Fang, J., Fargetta, M., Fatkina, A., Fedoseev, D., Fekete, V., Feng, L. -C., Feng, Q., Ford, R., Formozov, A., Fournier, A., Gan, H., Gao, F., Garfagnini, A., Gottel, A., Genster, C., Giammarchi, M., Giaz, A., Giudice, N., Giuliani, F., Gonchar, M., Gong, G., Gong, H., Gorchakov, O., Gornushkin, Y., Grassi, M., Grewing, C., Gromov, V., Gu, M., Gu, X., Gu, Y., Guan, M., Guardone, N., Gul, M., Guo, C., Guo, J., Guo, W., Guo, X., Guo, Y., Hackspacher, P., Hagner, C., Han, R., Han, Y., Hassan, M., He, M., He, W., Heinz, T., Hellmuth, P., Heng, Y., Herrera, R., Hong, D., Hor, Y., Hou, S., Hsiung, Y., Hu, B. -Z., Hu, H., Hu, J., Hu, S., Hu, T., Hu, Z., Huang, C., Huang, G., Huang, H., Huang, Q., Huang, W., Huang, X., Huang, Y., Hui, J., Huo, L., Huo, W., Huss, C., Hussain, S., Insolia, A., Ioannisian, A., Isocrate, R., Jelmini, B., Jen, K. -L., Ji, X., Jia, H., Jia, J., Jian, S., Jiang, D., Jiang, X., Jin, R., Jing, X., Jollet, C., Joutsenvaara, J., Jungthawan, S., Kalousis, L., Kampmann, P., Kang, L., Karagounis, M., Kazarian, N., Khan, A., Khan, W., Khosonthongkee, K., Kinz, P., Korablev, D., Kouzakov, K., Krasnoperov, A., Krokhaleva, S., Krumshteyn, Z., Kruth, A., Kutovskiy, N., Kuusiniemi, P., Lachenmaier, T., Landini, C., Leblanc, S., Lebrin, V., Lefevre, F., Lei, R., Leitner, R., Leung, J., Li, D., Li, F., Li, H., Li, J., Li, K., Li, M., Li, N., Li, Q., Li, R., Li, S., Li, T., Li, W., Li, X., Li, Y., Li, Z., Liang, H., Liang, J., Liebau, D., Limphirat, A., Limpijumnong, S., Lin, G. -L., Lin, S., Lin, T., Ling, J., Lippi, I., Liu, F., Liu, H., Liu, J., Liu, M., Liu, Q., Liu, R., Liu, S., Liu, X., Liu, Y., Lokhov, A., Lombardi, P., Lombardo, C., Loo, K., Lu, C., Lu, H., Lu, J., Lu, S., Lu, X., Lubsandorzhiev, B., Lubsandorzhiev, S., Ludhova, L., Luo, F., Luo, G., Luo, P., Luo, S., Luo, W., Lyashuk, V., Ma, Q., Ma, S., Ma, X., Maalmi, J., Malyshkin, Y., Mantovani, F., Manzali, F., Mao, X., Mao, Y., Mari, S. M., Marini, F., Marium, S., Martellini, C., Martin-Chassard, G., Martini, A., Mayilyan, D., Muller, A., Mednieks, I., Meng, Y., Meregaglia, A., Meroni, E., Meyhofer, D., Mezzetto, M., Miller, J., Miramonti, L., Monforte, S., Montini, P., Montuschi, M., Morozov, N., Muhammad, W., Muralidharan, P., Nastasi, M., Naumov, D. V., Naumova, E., Navas-Nicolas, D., Nemchenok, I., Ning, F., Ning, Z., Nunokawa, H., Oberauer, L., Ochoa-Ricoux, J. P., Olshevskiy, A., Orestano, D., Ortica, F., Pan, H. -R., Paoloni, A., Parkalian, N., Parmeggiano, S., Payupol, T., Pei, Y., Pelliccia, N., Peng, A., Peng, H., Perrot, F., Petitjean, P. -A., Petrucci, F., Rico, L. F. 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Subjects
Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, measurement methods, scintillation counter: liquid, energy resolution, FOS: Physical sciences, Photodetector, Scintillator, 01 natural sciences, NO, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), hal-03022811, PE2_2, Optics, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Calibration, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, ddc:530, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 010306 general physics, Astrophysique, Jiangmen Underground Neutrino Observatory, Physics, JUNO, liquid [scintillation counter], 010308 nuclear & particles physics, business.industry, Settore FIS/01 - Fisica Sperimentale, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Linearity, Instrumentation and Detectors (physics.ins-det), calibration, Neutrino Detectors and Telescopes (experiments), lcsh:QC770-798, High Energy Physics::Experiment, Neutrino, business, Energy (signal processing)
Abstract

We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-positional calibration program, in combination with a novel dual calorimetry technique exploiting two independent photosensors and readout systems, we demonstrate that the JUNO central detector can achieve a better than 1% energy linearity and a 3% effective energy resolution, required by the neutrino mass ordering determination. [Figure not available: see fulltext.], 0, info:eu-repo/semantics/published

Published
2021

43. Catalytic asymmetric nucleophilic fluorination using BF

Author

Weiwei, Zhu, Xiang, Zhen, Jingyuan, Wu, Yaping, Cheng, Junkai, An, Xingyu, Ma, Jikun, Liu, Yuji, Qin, Hao, Zhu, Jijun, Xue, and Xianxing, Jiang

Subjects
Asymmetric catalysis, Synthetic chemistry methodology, Article
Abstract

Fluorination using chiral catalytic methods could result in a direct access to asymmetric fluorine chemistry. However, challenges in catalytic asymmetric fluorinations, especially the longstanding stereochemical challenges existed in BF3·Et2O-based fluorinations, have not yet been addressed. Here we report the catalytic asymmetric nucleophilic fluorination using BF3·Et2O as the fluorine reagent in the presence of chiral iodine catalyst. Various chiral fluorinated oxazine products were obtained with good to excellent enantioselectivities (up to >99% ee) and diastereoselectivities (up to >20:1 dr). Control experiments (the desired fluoro-oxazines could not be obtained when Py·HF or Et3N·3HF were employed as the fluorine source) indicated that BF3·Et2O acted not only as a fluorine reagent but also as the activating reagent for activation of iodosylbenzene., Catalytic asymmetric fluorination remains elusive, especially the longstanding stereochemical challenges which exist in BF3Et2O-based fluorinations. Here the authors show a catalytic asymmetric nucleophilic fluorination using BF3·Et2O as the fluorine reagent in the presence of chiral iodine catalyst.

Published
2020

44. Gut feeling from Wuhan: advice for gastrointestinal endoscopy performed during the COVID-19 outbreak

Author

Yaping Cheng, Thanawat Luangsukrerk, Zhen Ding, Thawee Ratanachu-ek, Pradermchai Kongkam, Jun Liu, and Rungsun Rerknimitr

Subjects
Male, China, Safety Management, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), media_common.quotation_subject, Pneumonia, Viral, Video Recording, Risk Assessment, Endoscopy, Gastrointestinal, Disease Outbreaks, Betacoronavirus, Disease Transmission, Infectious, medicine, Humans, Pandemics, Occupational Health, Gastrointestinal endoscopy, media_common, Infection Control, medicine.diagnostic_test, SARS-CoV-2, business.industry, General surgery, Gastroenterology, COVID-19, Outbreak, Endoscopy, Feeling, Female, Patient Safety, Coronavirus Infections, business, Disease transmission
Published
2020
Full Text
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45. The Flash ADC system and PMT waveform reconstruction for the Daya Bay experiment

Author

Li Qiuju, Yongbo Huang, Fei Li, Yu Xu, Wei Wang, Yaping Cheng, Xiaolu Ji, S. Jetter, Zeyuan Yu, Xin Qian, Jin Li, Jinfan Chang, Zhang Chen, Zheng Wang, and Jun Hu

Subjects
Physics, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, business.industry, Monte Carlo method, Detector, Electrical engineering, FOS: Physical sciences, Analog-to-digital converter, Linearity, Instrumentation and Detectors (physics.ins-det), Daya Bay Reactor Neutrino Experiment, Flash ADC, 01 natural sciences, law.invention, Data acquisition, law, 0103 physical sciences, Electronic engineering, Waveform, 010306 general physics, business, Instrumentation
Abstract

To better understand the energy response of the Antineutrino Detector (AD), the Daya Bay Reactor Neutrino Experiment installed a full Flash ADC readout system on one AD that allowed for simultaneous data taking with the current readout system. This paper presents the design, data acquisition, and simulation of the Flash ADC system, and focuses on the PMT waveform reconstruction algorithms. For liquid scintillator calorimetry, the most critical requirement to waveform reconstruction is linearity. Several common reconstruction methods were tested but the linearity performance was not satisfactory. A new method based on the deconvolution technique was developed with 1% residual non-linearity, which fulfills the requirement. The performance was validated with both data and Monte Carlo (MC) simulations, and 1% consistency between them has been achieved.

Published
2018

47. A 300-mA load CMOS low-dropout regulator without an external capacitor for SoC and embedded applications

Author

Quanzhen Duan, Yaping Cheng, Jiaqi Yin, Tian Guo, Yuemin Ding, and Shengming Huang

Subjects
Engineering, Low-dropout regulator, business.industry, Applied Mathematics, Amplifier, 020208 electrical & electronic engineering, 020206 networking & telecommunications, Slew rate, Line regulation, 02 engineering and technology, Computer Science Applications, Electronic, Optical and Magnetic Materials, law.invention, Capacitor, CMOS, law, Load regulation, 0202 electrical engineering, electronic engineering, information engineering, Electronic engineering, Electrical and Electronic Engineering, business, Voltage
Abstract

Summary This study proposes a 300-mA external capacitor-free low-dropout (LDO) regulator for system-on-chip and embedded applications. To achieve a full-load range from 0 to 300 mA, a two-scheme (a light-load case and a heavy-load case) operation LDO regulator with a novel control circuit is proposed. In the light-load case (0–0.5 mA), only one P-type metal–oxide–semiconductor input-pair amplifier with a 10-pF on-chip capacitor is used to obtain a load current as low as 0. In the heavy-load case (0.5 to 300 mA), both P-type metal–oxide–semiconductor and N-type metal–oxide–semiconductor differential input-pair amplifiers with an assistant push-pull stage are utilized to improve the stability of the LDO regulator and achieve a high slew rate and fast-transient response. Measurements show an output voltage of 3.3 V and a full output load range from 0 to 300 mA. A line regulation of 1.66 mV/V and a load regulation of 0.0334 mV/mA are achieved. The measured power-supply rejection ratio at 1 kHz is −65 dB, and the measured output noise is only 34 μV. The total active chip size is approximately 0.4 mm2 with a standard 0.5 μm complementary metal–oxide–semiconductor process. Copyright © 2017 John Wiley & Sons, Ltd.

Published
2017

48. Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Author

Yani, Zhou, Nannan, Chen, Yaping, Cheng, and Xiaoqing, Cai

Subjects
Lactones, Cycloaddition Reaction, Stereoisomerism, Pyrazolones, Crystallography, X-Ray
Abstract

Bispirocyclic scaffolds are one of the important structural subunits in many natural products that exhibit diverse and attractive biological activities. Recently, we have developed an efficient organocatalytic strategy, which provides facile access to a variety of enantiomerically enriched bispiro[γ-butyrolactone-pyrrolidin-4,4'-pyrazolone] skeletons. In this paper, we demonstrate a detailed protocol for the asymmetric synthesis of drug-like bispirocyclic compounds with two spirocyclic carbon centers via an organocatyltic 1,3-dipolar cycloaddition reaction. Spirocyclization synthons α-imino γ-lactones and alkylidene pyrazolones are prepared first, which are then subjected to a cycloaddition reaction in the presence of a bifunctional squaramide organocatalyst to afford the desired bispirocycles in high yields and excellent stereoselectivities. Chiral high-performance liquid chromatography (HPLC) is carried out to determine the enantiomeric purity of the products, and the d.r. value is examined by proton nuclear magnetic resonance (

Published
2019

49. A novel PANI@Carbon dot hybrid with enhanced electrochemical and electrochromic properties

Author

Jia Chu, Shanxin Xiong, Yaping Cheng, Fan Yang, and Xue Li

Subjects
Materials science, Mechanical Engineering, Ionic bonding, chemistry.chemical_element, Nanotechnology, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Electrochemistry, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Aniline, chemistry, Mechanics of Materials, Electrochromism, Copolymer, General Materials Science, Thin film, 0210 nano-technology, Layer (electronics), Carbon
Abstract

A novel Polyaniline@carbon dot (PANI@C-dot) hybrid was synthesized through copolymerization of aniline in the presence of carbon dots (C-dots) suspension. The PANI@C-dot hybrid thin film exhibits higher optical contrast and faster switching speed compared to the pristine PANI. The enhanced electrochromic performance was presumably due to the synergistic effect between the PANI and C-dots, which improved the electron transport and ionic motion of the electrochromic layer. Thus, the PANI@C-dot hybrid opens a new avenue for developing of C-dots based electrochromic materials and uses in energy conversation and storage devices.

Published
2020

50. Novel prussian blue@Carbon-dots hybrid thin film: The impact of carbon-dots on material structure and electrochromic performance

Author

Xue Li, Jia Chu, Yaping Cheng, Fan Yang, and Shanxin Xiong

Subjects
Prussian blue, Materials science, General Chemical Engineering, chemistry.chemical_element, Ionic bonding, Nanotechnology, 02 engineering and technology, Substrate (electronics), 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, symbols.namesake, chemistry, X-ray photoelectron spectroscopy, Electrochromism, Electrochemistry, symbols, Thin film, 0210 nano-technology, Raman spectroscopy, Carbon
Abstract

Herewith, a series of Prussian blue@Carbon-dot (P@C-dot) hybrids were directly grown on FTO substrate by simple, one-step hydrothermal method in different dosage of aqueous dispersion of carbon dots. Being a new class of carbon allotropes, Carbon dot (C-dot) hybridized with Prussian blue (PB) will enhance the electroactivity of the hybrid film. It was found that the incorporation of C-dots influences the appearance color of the sample, the microstrucutre and electrochromic performance of the hybrids. Raman and XPS analysis revealed structural changes of the hybrid with different dosage of C-dots. The P@C-dot hybrid film exhibits a high-contrast electrochromism, fast response time and highly reversible nature compared to the sample without C-dots. This improved performance of P@C-dot hybrids can be attributed to the role of reinforced C-dots in facilitating electron transport and ionic motion in the hybrid film. Thus, the P@C-dot hybrid film provides a versatile and promising application towards the fabrication of smart windows.

Published
2020

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