150 results on '"Yaoqi Li"'
Search Results
2. SNP alleviates mitochondrial homeostasis dysregulation-mediated developmental toxicity in diabetic zebrafish larvae
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Yingying Jiang, Yu Cao, Yaoqi Li, Liuliu Bi, Lv Wang, Qianqian Chen, Yue Lin, Huanzhi Jin, Xiaoming Xu, Renyi Peng, and Zheyan Chen
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Diabetes ,Mitochondrial homeostasis ,Apoptosis ,Ferroptosis ,Inflammation ,Therapeutics. Pharmacology ,RM1-950 - Abstract
The incidence of diabetes is increasing annually, and the disease is uncurable due to its complex pathogenesis. Therefore, understanding diabetes pathogenesis and developing new treatments are crucial. This study showed that the NO donor SNP (8 µM) significantly alleviated high glucose-induced developmental toxicity in zebrafish larvae. High glucose levels caused hyperglycemia, leading to oxidative stress and mitochondrial damage from excessive ROS accumulation. This promoted mitochondrial-dependent apoptosis and lipid peroxidation (LPO)-induced ferroptosis, along with immune inflammatory reactions that decreased mitochondrial function and altered intracellular grid morphology, causing imbalanced kinetics and autophagy. After SNP treatment, zebrafish larvae showed improved developmental toxicity and glucose utilization, reduced ROS accumulation, and increased antioxidant activity. The NO-sGC-cGMP signaling pathway, inhibited by high glucose, was significantly activated by SNP, improving mitochondrial homeostasis, increasing mitochondrial count, and enhancing mitochondrial function. It's worth noting that apoptosis, ferroptosis and immune inflammation were effectively alleviated. In summary, SNP improved high glucose-induced developmental toxicity by activating the NO-sGC-cGMP signaling pathway to reduce toxic effects such as apoptosis, ferroptosis and inflammation resulting from mitochondrial homeostasis imbalance.
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- 2024
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3. Elucidating hepatocellular carcinoma progression: a novel prognostic miRNA–mRNA network and signature analysis
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Fei Wang, Xichun Kang, Yaoqi Li, Jianhua Lu, Xiling Liu, and Huimin Yan
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Hepatocellular carcinoma ,miRNA ,Prognosis ,miRNA–mRNA network ,Medicine ,Science - Abstract
Abstract There is increasing evidence that miRNAs play an important role in the prognosis of HCC. There is currently a lack of acknowledged models that accurately predict patient prognosis. The aim of this study is to create a miRNA-based model to precisely forecast a patient’s prognosis and a miRNA–mRNA network to investigate the function of a targeted mRNA. TCGA miRNA dataset and survival data of HCC patients were downloaded for differential analysis. The outcomes of variance analysis were subjected to univariate and multivariate Cox regression analyses and LASSO analysis. We constructed and visualized prognosis-related models and subsequently used violin plots to probe the function of miRNAs in tumor cells. We predicted the target mRNAs added those to the String database, built PPI protein interaction networks, and screened those mRNA using Cytoscape. The hub mRNA was subjected to GO and KEGG analysis to determine its biological role. Six of them were associated with prognosis: hsa-miR-139-3p, hsa-miR-139-5p, hsa-miR-101-3p, hsa-miR-30d-5p, hsa-miR-5003-3p, and hsa-miR-6844. The prognostic model was highly predictive and consistently performs, with the C index exceeding 0.7 after 1, 3, and 5 years. The model estimated significant differences in the Kaplan–Meier plotter and the model could predict patient prognosis independently of clinical indicators. A relatively stable miRNA prognostic model for HCC patients was constructed, and the model was highly accurate in predicting patients with good stability over 5 years. The miRNA–mRNA network was constructed to explore the function of mRNA.
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- 2024
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4. Plant traits and associated data from a warming experiment, a seabird colony, and along elevation in Svalbard
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Vigdis Vandvik, Aud H. Halbritter, Inge H. J. Althuizen, Casper T. Christiansen, Jonathan J. Henn, Ingibjörg Svala Jónsdóttir, Kari Klanderud, Marc Macias-Fauria, Yadvinder Malhi, Brian Salvin Maitner, Sean Michaletz, Ruben E. Roos, Richard J. Telford, Polly Bass, Katrín Björnsdóttir, Lucely Lucero Vilca Bustamante, Adam Chmurzynski, Shuli Chen, Siri Vatsø Haugum, Julia Kemppinen, Kai Lepley, Yaoqi Li, Mary Linabury, Ilaíne Silveira Matos, Barbara M. Neto-Bradley, Molly Ng, Pekka Niittynen, Silje Östman, Karolína Pánková, Nina Roth, Matiss Castorena, Marcus Spiegel, Eleanor Thomson, Alexander Sæle Vågenes, and Brian J. Enquist
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Science - Abstract
Abstract The Arctic is warming at a rate four times the global average, while also being exposed to other global environmental changes, resulting in widespread vegetation and ecosystem change. Integrating functional trait-based approaches with multi-level vegetation, ecosystem, and landscape data enables a holistic understanding of the drivers and consequences of these changes. In two High Arctic study systems near Longyearbyen, Svalbard, a 20-year ITEX warming experiment and elevational gradients with and without nutrient input from nesting seabirds, we collected data on vegetation composition and structure, plant functional traits, ecosystem fluxes, multispectral remote sensing, and microclimate. The dataset contains 1,962 plant records and 16,160 trait measurements from 34 vascular plant taxa, for 9 of which these are the first published trait data. By integrating these comprehensive data, we bridge knowledge gaps and expand trait data coverage, including on intraspecific trait variation. These data can offer insights into ecosystem functioning and provide baselines to assess climate and environmental change impacts. Such knowledge is crucial for effective conservation and management in these vulnerable regions.
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- 2023
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5. Risk factors for gastroparesis syndrome after radical gastric cancer surgery
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Ciba Zhu, Mingxu Da, Jichun Ma, and Yaoqi Li
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Surgery ,RD1-811 - Published
- 2024
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6. Tight relationships between leaf and topsoil stoichiometries after 42 years of forest conversion from old-growth forests to Chinese fir plantations
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Cancan Zhang, Yuxin Li, Xin Li, Fusheng Chen, Zhifang Jin, Yaoqi Li, Yaohua Ma, Shiqi Zeng, Shiyun Yang, and Wensheng Bu
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forest conversion ,subtropical forests ,topography ,soil stoichiometry ,leaf stoichiometry ,Forestry ,SD1-669.5 ,Environmental sciences ,GE1-350 - Abstract
Soil C:N:P stoichiometry can regulate plant survival and reflect soil fertility and nutrient utilization. Despite the widespread conversion of old-growth forests to plantations or secondary forests, there is little knowledge about how these conversions affect the relation between leaf and soil stoichiometries. We examined the topography, leaf, and soil stoichiometries of 75 plots (20 m × 20 m) across Chinese fir plantations, secondary forests, and old-growth forests in subtropical China. We found that: (1) There were significant differences in leaf carbon, nitrogen, phosphorus, and their stoichiometry ratios among different stand types (2) stand type significantly affected soil SOC, TP, C:N, C:P, and N:P, except TN and (3) the explanation percentage of leaf stoichiometry on soil stoichiometry doubled with the conversion of old-growth forest to Chinese fir plantation, whereas it was twofold decreased with the conversion of old-growth forest to secondary forest. The explanation percentage of topography on soil stoichiometry decreased onefold at a minimum with the conversion of the old-growth forest to the Chinese fir plantation or the secondary forest. Our results show the shortages of soil nutrients from transforming old-growth forests into plantations or secondary forests and indicate the urgent need to preserve the remaining old-growth forests and increase stand ages by reducing forest disturbances. Therefore, determining the optimal stand type and slope location can effectively promote the accumulation of carbon, nitrogen, and phosphorus nutrients in the topsoil, which is essential for improving the planning and implementation of appropriate forest restoration and ecosystem management strategies.
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- 2023
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7. Environmental determinants of aquatic plant diversity differ between growth forms and range sizes
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Jianan Zhou, Yaoqi Li, Tong Lyu, Haihao Yu, Jiahui Meng, Wenqi Song, Yulin Kang, Dan Yu, and Zhiheng Wang
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Freshwater vegetation ,Geographic patterns ,Submerged plant ,Species richness ,Narrow-ranged species ,Emergent plant ,Ecology ,QH540-549.5 - Abstract
Aquatic plants are fundamental for aquatic ecosystems. Understanding variations in geographic patterns of aquatic plant diversity across growth forms is important for conservation and restoration of aquatic ecosystems. Environmental drivers, including climate, climate heterogeneity, water chemistry, habitat availability and geodiversity, could influence aquatic plant diversity and species composition across communities, yet their relative impacts remain controversial. Here, we examined geographic patterns and drivers of species richness of Chinese aquatic plants with different growth forms. We compiled distributions of 656 aquatic plant species in China at 50 × 50 km2 resolutions, and estimated richness patterns for species with different growth forms (i.e., helophyte, emergent, floating-leaved, free-drifting and submerged) and range sizes. Hierarchical partitioning analysis was employed to evaluate the independent effects of different environmental drivers on species richness. The Sørensen dissimilarity index and Multiple Matrix Regression with Randomization were used to compare the relative effects of environment and dispersal limitation on species dissimilarity between grid cells. Overall species richness was highest in northeastern and southern China, although species richness patterns varied across growth forms. Among environmental drivers examined, climate was the key determinant of the species richness of helophyte, emergent, floating-leaved and free-drifting plants, while habitat availability and water chemistry best explained the richness of submerged species. The richness of narrow-ranged species was dominated by climate, while the strongest determinant of wide-ranged species richness varied across growth forms. Our study mapped the species richness patterns of aquatic plants in China and indicated that the relationship between aquatic plant richness and environment significantly differed between growth forms and between wide-ranged and narrow-ranged species. These findings indicate the necessity of distinguishing growth forms in studies related to aquatic plants, and suggest that future climate change might threaten the distribution of narrow-ranged aquatic plants.
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- 2023
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8. Hydrogen sulfide-induced oxidative stress mediated apoptosis via mitochondria pathway in embryo-larval stages of zebrafish
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Yinai Liu, Qianqian Chen, Yaoqi Li, Liuliu Bi, Sue Lin, Hao Ji, Da Sun, Libo Jin, and Renyi Peng
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Hydrogen sulfide ,Zebrafish ,ROS ,Mitochondrial dysfunction ,Apoptosis ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Hydrogen sulfide (H2S), a highly toxic gas, has become a polluting gas that cannot be ignored, while H2S exposure results in acute or chronic poisoning or even death in humans or animals and plants, but the relevant mechanisms remain poorly understood. In this study, 9-day-old zebrafish larvae were exposed continuously to culture medium containing 30 μM survival rate was counted on H2S, and our results indicated that H2S exposure increased intracellular ROS, Ca2+, NO and MDA contents and decreased SOD activity, meaning that H2S caused oxidative stress in embryo-larval stages of zebrafish. Furthermore, we found that transgenic zebrafish (cms Tg/+ AB) displayed a lower fluorescence intensity, and cytochrome c oxidase (COX) activity and JC-1 monomer fluorescence ratio increased under H2S treatment conditions. These findings indicated that H2S caused mitochondrial dysfunction. Moreover, in this experiment, after H2S treatment, the increase of apoptotic cells, activity of caspase 3 and transcription of typical apoptosis-associated genes including BCL2 associated agonist of cell death (Bad), and BCL2 associated X apoptosis (Baxa) and so on were found, which suggested that H2S caused apoptosis in zebrafish larvae. Therefore, our data meant that H2S-traggered oxidative stress mediate mitochondrial dysfunction, thus triggering apoptosis. In conclusion, oxidative stress triggered H2S-induced apoptosis via mitochondria pathway in embryo-larval stages of zebrafish.
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- 2022
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9. PET evaluation of light-induced modulation of microglial activation and GLP-1R expression in depressive rats
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Yu Liu, Lizhen Wang, Donghui Pan, Mingzhu Li, Yaoqi Li, Yan Wang, Yuping Xu, Xinyu Wang, Junjie Yan, Qiong Wu, Lin Lu, Kai Yuan, and Min Yang
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Abstract Light therapy has been accepted as a promising therapeutic choice for depression. Positron emission tomography (PET) combined with specific radiotracers has great benefits for revealing pathogenesis and developing therapeutics. This study aimed to investigate the influences of light therapy on microglial activation and glucagon-like peptide-1 receptor (GLP-1R) expression in the brain of depressive rats using [18F]DPA-714 and [18F]exendin-4 PET. The results showed that chronic unpredictable mild stress (CUMS)-induced depressive rats had poorer performance in behavioral tests compared to normal rats (p
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- 2021
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10. Toxic Effects of Cadmium on Fish
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Yinai Liu, Qianqian Chen, Yaoqi Li, Liuliu Bi, Libo Jin, and Renyi Peng
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aquatic ecosystems ,food chain ,cadmium accumulation ,cadmium toxicity ,oxidative stress ,Chemical technology ,TP1-1185 - Abstract
Large amounts of enriched cadmium (Cd) in the environment seriously threatens the healthy and sustainable development of the aquaculture industry and greatly restricts the development of the food processing industry. Studying the distribution and toxic effects of Cd in fish, as well as the possible toxic effects of Cd on the human body, is very significant. A large number of studies have shown that the accumulation and distribution of Cd in fish are biologically specific, cause tissue differences, and seriously damage the integrity of tissue structure and function, the antioxidant defense system, the reproductive regulation system, and the immune system. The physiological, biochemical, enzyme, molecular, and gene expression levels change with different concentrations and times of Cd exposure, and these changes are closely related to the target sites of Cd action and tissues in fish. Therefore, the toxic effects of Cd on fish occur with multiple tissues, systems, and levels.
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- 2022
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11. Study on the clinical characteristics of functional dyspepsia patients with or without depression
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Weidong Li, Chenglou Zhu, Yaoqi Li, and Junfeng Ma
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Surgery ,RD1-811 - Published
- 2022
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12. Crosstalk between Ca2+ and Other Regulators Assists Plants in Responding to Abiotic Stress
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Yaoqi Li, Yinai Liu, Libo Jin, and Renyi Peng
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Ca2+ ,abiotic stress response ,Ca2+ sensors ,signal transduction ,abiotic stress tolerance calcium ,heat stress ,Botany ,QK1-989 - Abstract
Plants have evolved many strategies for adaptation to extreme environments. Ca2+, acting as an important secondary messenger in plant cells, is a signaling molecule involved in plants’ response and adaptation to external stress. In plant cells, almost all kinds of abiotic stresses are able to raise cytosolic Ca2+ levels, and the spatiotemporal distribution of this molecule in distant cells suggests that Ca2+ may be a universal signal regulating different kinds of abiotic stress. Ca2+ is used to sense and transduce various stress signals through its downstream calcium-binding proteins, thereby inducing a series of biochemical reactions to adapt to or resist various stresses. This review summarizes the roles and molecular mechanisms of cytosolic Ca2+ in response to abiotic stresses such as drought, high salinity, ultraviolet light, heavy metals, waterlogging, extreme temperature and wounding. Furthermore, we focused on the crosstalk between Ca2+ and other signaling molecules in plants suffering from extreme environmental stress.
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- 2022
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13. Effects of Climate, Plant Height, and Evolutionary Age on Geographical Patterns of Fruit Type
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Tong Lyu, Yunyun Wang, Ao Luo, Yaoqi Li, Shijia Peng, Hongyu Cai, Hui Zeng, and Zhiheng Wang
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fleshy fruit ,geographic pattern ,angiosperm ,China ,plant height ,macroevolution ,Plant culture ,SB1-1110 - Abstract
Fruit type is a key reproductive trait associated with plant evolution and adaptation. However, large-scale geographical patterns in fruit type composition and the mechanisms driving these patterns remain to be established. Contemporary environment, plant functional traits and evolutionary age may all influence fruit type composition, while their relative importance remains unclear. Here, using data on fruit types, plant height and distributions of 28,222 (∼ 90.1%) angiosperm species in China, we analyzed the geographical patterns in the proportion of fleshy-fruited species for all angiosperms, trees, shrubs, and herbaceous species separately, and compared the relative effects of contemporary climate, ecosystem primary productivity, plant height, and evolutionary age on these patterns. We found that the proportion of fleshy-fruited species per grid cell for all species and different growth forms all showed significant latitudinal patterns, being the highest in southeastern China. Mean plant height per grid cell and actual evapotranspiration (AET) representing ecosystem primary productivity were the strongest drivers of geographical variations in the proportion of fleshy-fruited species, but their relative importance varied between growth forms. From herbaceous species to shrubs and trees, the relative effects of mean plant height decreased. Mean genus age had significant yet consistently weaker effects on proportion of fleshy-fruited species than mean plant height and AET, and environmental temperature and precipitation contributed to those of only trees and shrubs. These results suggest that biotic and environmental factors and evolutionary age of floras jointly shape the pattern in proportion of fleshy-fruited species, and improve our understanding of the mechanisms underlying geographical variations in fruit type composition. Our study also demonstrates the need of integrating multiple biotic and abiotic factors to fully understand the drivers of large-scale patterns of plant reproductive traits.
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- 2021
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14. Spatial Patterns and Drivers of Angiosperm Sexual Systems in China Differ Between Woody and Herbaceous Species
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Yunyun Wang, Tong Lyu, Ao Luo, Yaoqi Li, Yunpeng Liu, Robert P. Freckleton, Shuguang Liu, and Zhiheng Wang
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angiosperms ,sexual systems ,growth form ,climate change ,geographical pattern ,macro evo-devo ,Plant culture ,SB1-1110 - Abstract
Plant sexual systems play an important role in the evolution of angiosperm diversity. However, large-scale patterns in the frequencies of sexual systems (i.e. dioecy, monoecy, and hermaphroditism) and their drivers for species with different growth forms remain poorly known. Here, using a newly compiled database on the sexual systems and distributions of 19780 angiosperm species in China, we map the large-scale geographical patterns in frequencies of the sexual systems of woody and herbaceous species separately. We use these data to test the following two hypotheses: (1) the prevalence of sexual systems differs between woody and herbaceous assemblies because woody plants have taller canopies and are found in warm and humid climates; (2) the relative contributions of different drivers (specifically climate, evolutionary age, and mature plant height) to these patterns differ between woody and herbaceous species. We show that geographical patterns in proportions of different sexual systems (especially dioecy) differ between woody and herbaceous species. Geographical variations in sexual systems of woody species were influenced by climate, evolutionary age and plant height. In contrast, these have only weakly significant effects on the patterns of sexual systems of herbaceous species. We suggest that differences between species with woody and herbaceous growth forms in terms of biogeographic patterns of sexual systems, and their drivers, may reflect their differences in physiological and ecological adaptions, as well as the coevolution of sexual system with vegetative traits in response to environmental changes.
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- 2020
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15. Hydrogen Sulfide Enhances Plant Tolerance to Waterlogging Stress
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Yaoqi Li, Da Sun, Ke Xu, Libo Jin, and Renyi Peng
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hydrogen sulfide ,waterlogging ,reactive oxygen species ,gas signaling molecule ,hypoxia tolerance ,Botany ,QK1-989 - Abstract
Hydrogen sulfide (H2S) is considered the third gas signal molecule in recent years. A large number of studies have shown that H2S not only played an important role in animals but also participated in the regulation of plant growth and development and responses to various environmental stresses. Waterlogging, as a kind of abiotic stress, poses a serious threat to land-based waterlogging-sensitive plants, and which H2S plays an indispensable role in response to. In this review, we summarized that H2S improves resistance to waterlogging stress by affecting lateral root development, photosynthetic efficiency, and cell fates. Here, we reviewed the roles of H2S in plant resistance to waterlogging stress, focusing on the mechanism of its promotion to gained hypoxia tolerance. Finally, we raised relevant issues that needed to be addressed.
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- 2021
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16. Multiscale mapping of plant functional groups and plant traits in the High Arctic using field spectroscopy, UAV imagery and Sentinel-2A data
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Eleanor R Thomson, Marcus P Spiegel, Inge H J Althuizen, Polly Bass, Shuli Chen, Adam Chmurzynski, Aud H Halbritter, Jonathan J Henn, Ingibjörg S Jónsdóttir, Kari Klanderud, Yaoqi Li, Brian S Maitner, Sean T Michaletz, Pekka Niittynen, Ruben E Roos, Richard J Telford, Brian J Enquist, Vigdis Vandvik, Marc Macias-Fauria, and Yadvinder Malhi
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Svalbard ,functional trait ,tundra ,moss ,shrubs ,remote sensing ,Environmental technology. Sanitary engineering ,TD1-1066 ,Environmental sciences ,GE1-350 ,Science ,Physics ,QC1-999 - Abstract
The Arctic is warming twice as fast as the rest of the planet, leading to rapid changes in species composition and plant functional trait variation. Landscape-level maps of vegetation composition and trait distributions are required to expand spatially-limited plot studies, overcome sampling biases associated with the most accessible research areas, and create baselines from which to monitor environmental change. Unmanned aerial vehicles (UAVs) have emerged as a low-cost method to generate high-resolution imagery and bridge the gap between fine-scale field studies and lower resolution satellite analyses. Here we used field spectroscopy data (400–2500 nm) and UAV multispectral imagery to test spectral methods of species identification and plant water and chemistry retrieval near Longyearbyen, Svalbard. Using the field spectroscopy data and Random Forest analysis, we were able to distinguish eight common High Arctic plant tundra species with 74% accuracy. Using partial least squares regression (PLSR), we were able to predict corresponding water, nitrogen, phosphorus and C:N values ( r ^2 = 0.61–0.88, RMSEmean = 12%–64%). We developed analogous models using UAV imagery (five bands: Blue, Green, Red, Red Edge and Near-Infrared) and scaled up the results across a 450 m long nutrient gradient located underneath a seabird colony. At the UAV level, we were able to map three plant functional groups (mosses, graminoids and dwarf shrubs) at 72% accuracy and generate maps of plant chemistry. Our maps show a clear marine-derived fertility gradient, mediated by geomorphology. We used the UAV results to explore two methods of upscaling plant water content to the wider landscape using Sentinel-2A imagery. Our results are pertinent for high resolution, low-cost mapping of the Arctic.
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- 2021
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17. Developing 360-degree stimuli for virtual tourism research: a five-step mixed measures procedure.
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Biqiang Liu, Anna Kralj, Brent Moyle, and Yaoqi Li
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- 2024
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18. Does physical attractiveness facilitate customer citizenship behaviors? Cross-cultural evidence from the peer-to-peer economy.
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Shuang Ma, Xiaodie Ling, Chun Zhang, and Yaoqi Li
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- 2023
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19. Speech VS. Writing: The influences of WOM communication on tourism experience storytellers
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Shujie Fang, Yaoqi Li, Chun Zhang, and Lulu Ye
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Tourism, Leisure and Hospitality Management - Published
- 2023
20. Celebrity endorsement in international destination marketing: Evidence from eye-tracking techniques and laboratory experiments
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Yaoqi Li, Biqiang Liu, and Lishan Xie
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Marketing - Published
- 2022
21. Global biodiversity patterns of woody and herbaceous flowering plants in space and time
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Ao Luo, Xiaoting Xu, Yunpeng Liu, Yaoqi Li, Xiangyan Su, Yichao Li, Tong Lyu, Dimitar Dimitrov, Markku Larjavaara, Shijia Peng, Yongsheng Chen, Qinggng Wang, Niklaus Zimmermann, Loïc Pellissier, Bernhard Schmid, and Zhiheng Wang
- Abstract
Plant biodiversity can be structured into different growth forms (i.e. woody vs. herbaceous) with divergent distributions, evolutionary histories, and relationships with climate thus they should be separately analyzed to better understand plant diversity. Flowering plants (angiosperms) are the most successful group of plants and have a diversity of growth forms that differs from other groups such as gymnosperms, all of which are woody species. However, there is still a gap in current growth form databases to cover most angiosperms. To fill the gap, this study collect data on growth forms of angiosperm species from published floras, online databases, and peer-reviewed journal articles and compiled a massive database of growth forms (woody and herbaceous, 300,750 species). Combined with distributions of 332,293 species, we mapped the current global geographical patterns in woody and herbaceous species as well as their relative proportion and assess their relationship with climate. This study also reconstructed ancestral states of growth forms through the angiosperm phylogeny to demonstrate the Cenozoic evolutionary dynamics of growth forms and explore the evolutionary transitions between the two growth forms.
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- 2023
22. Deep Learning for Stock Selection Based on High Frequency Price-Volume Data.
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Junming Yang, Yaoqi Li, Xuanyu Chen, Jiahang Cao, and Kangkang Jiang
- Published
- 2019
23. The antecedents of customer mistreatment: a meta-analytic review
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Pei Liu, Yu Ma, Xin Li, Caodie Peng, and Yaoqi Li
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Tourism, Leisure and Hospitality Management - Abstract
PurposeFrontline service employees are often subjected to customer mistreatment and considerable studies have tested outcomes of customer mistreatment. However, the importance of its antecedents is particularly underestimated. This meta-analytic paper aims to develop an overarching framework that identifies the antecedents of customer mistreatment as well as potential boundary conditions to account for observed variations reported in extant studies.Design/methodology/approachComprehensive electronic and manual searches were performed to retrieve relevant studies on customer mistreatment, which yielded 125 articles, including 141 independent samples. Altogether, these studies included 40,151 participants. The data were analyzed through random-effect meta-analytic methods in R using the psychmeta package.FindingsThree types of antecedents were identified. In particular, regarding employees’ demographic characteristics, age was found to be negatively correlated with customer mistreatment. Employees’ personality traits such as agreeableness, conscientiousness, positive affectivity, emotion regulation ability and self-efficacy were found to be negatively correlated with customer mistreatment, while neuroticism and negative affectivity were positively correlated with customer mistreatment. In terms of contextual factors, perceived social support and service climate were negatively related to customer mistreatment, whereas job demands were positively related to customer mistreatment. Moreover, the power distance culture and types of service industries moderated some relationships.Originality/valueThis meta-analytic research, drawing upon the perpetrator predation framework, proposed a new and comprehensive framework to explain why customer mistreatment occurs. It not only promoted the advancement of literature on customer mistreatment but also provided effective and targeted guidance for helping frontline service employees reduce such negative experience.
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- 2022
24. Time perception and tourist behavioral decision when travelling
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Yaoqi Li, Yaya Song, and Shujie Fang
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Tourism, Leisure and Hospitality Management ,Geography, Planning and Development - Published
- 2022
25. The impact of customer sexual harassment on customer-oriented OCB: a social exchange perspective
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Hong Zhu, Yijiao Ye, Mingjian Zhou, and Yaoqi Li
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Tourism, Leisure and Hospitality Management - Abstract
Purpose Drawing on social exchange theory, this study aims to investigate the relation of customer sexual harassment (CSH) and customer-oriented organizational citizenship behaviors (customer-oriented OCB), as well as the mediation of customer–employee exchange (CEX) and the moderation of hostile attribution bias. Design/methodology/approach The hypotheses were examined through a field study performed in six hotels in three Chinese cities and an experimental study. Findings The results revealed that CSH undermined the quality of CEX, leading employees to withdraw from customer-oriented OCB. Additionally, the hostile attribution bias of service employees reinforced the direct relationship between CSH and CEX and its indirect relationship with customer-oriented OCB via CEX. Practical implications The findings suggest that hospitality organizations should endeavor to reduce the occurrence of CSH, and that by valuing and encouraging the development of high-quality CEX, they can mitigate its detrimental effects. Special attention should also be paid to hospitality employees holding strong hostile attribution bias. Originality/value First, to the best of the authors’ knowledge, this is one of the first studies to explore the influence of CSH on customer-oriented OCB among hotel employees. In addition, examining the effect of CSH from the social exchange perspective represents a new theoretical approach. The finding also contributes to the literature on CEX by identifying an important antecedent. Finally, by investigating hostile attribution bias as a moderator, this research provides insights into how individual differences moderate the destructive influence of CSH.
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- 2023
26. Evolutionary history and global angiosperm species richness–climate relationships
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Ke Jiang, Qinggang Wang, Dimitar Dimitrov, Ao Luo, Xiaoting Xu, Xiangyan Su, Yunpeng Liu, Yaoqi Li, Yichao Li, and Zhiheng Wang
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Global and Planetary Change ,Ecology ,Ecology, Evolution, Behavior and Systematics - Published
- 2023
27. A review of the heterogeneous landscape of biodiversity databases: Opportunities and challenges for a synthesized biodiversity knowledge base
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Xiao Feng, Brian J. Enquist, Daniel S. Park, Brad Boyle, David D. Breshears, Rachael V. Gallagher, Aaron Lien, Erica A. Newman, Joseph R. Burger, Brian S. Maitner, Cory Merow, Yaoqi Li, Kimberly M. Huynh, Kacey Ernst, Elizabeth Baldwin, Wendy Foden, Lee Hannah, Peter M. Jørgensen, Nathan J. B. Kraft, Jon C. Lovett, Pablo A. Marquet, Brian J. McGill, Naia Morueta‐Holme, Danilo M. Neves, Mauricio M. Núñez‐Regueiro, Ary T. Oliveira‐Filho, Robert K. Peet, Michiel Pillet, Patrick R. Roehrdanz, Brody Sandel, Josep M. Serra‐Diaz, Irena Šímová, Jens‐Christian Svenning, Cyrille Violle, Trang D. Weitemier, Susan Wiser, Laura López‐Hoffman, and Allen Hurlbert
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database integration ,Global and Planetary Change ,taxonomic system ,Ecology ,big data ,biodiversity informatics ,functional trait ,biogeography ,Ecology, Evolution, Behavior and Systematics - Abstract
Aim: Addressing global environmental challenges requires access to biodiversity data across wide spatial, temporal and taxonomic scales. Availability of such data has increased exponentially recently with the proliferation of biodiversity databases. However, heterogeneous coverage, protocols, and standards have hampered integration among these databases. To stimulate the next stage of data integration, here we present a synthesis of major databases, and investigate (a) how the coverage of databases varies across taxonomy, space, and record type; (b) what degree of integration is present among databases; (c) how integration of databases can increase biodiversity knowledge; and (d) the barriers to database integration. Location: Global. Time period: Contemporary. Major taxa studied: Plants and vertebrates. Methods: We reviewed 12 established biodiversity databases that mainly focus on geographic distributions and functional traits at global scale. We synthesized information from these databases to assess the status of their integration and major knowledge gaps and barriers to full integration. We estimated how improved integration can increase the data coverage for terrestrial plants and vertebrates. Results: Every database reviewed had a unique focus of data coverage. Exchanges of biodiversity information were common among databases, although not always clearly documented. Functional trait databases were more isolated than those pertaining to species distributions. Variation and potential incompatibility of taxonomic systems used by different databases posed a major barrier to data integration. We found that integration of distribution databases could lead to increased taxonomic coverage that corresponds to 23 years’ advancement in data accumulation, and improvement in taxonomic coverage could be as high as 22.4% for trait databases. Main conclusions: Rapid increases in biodiversity knowledge can be achieved through the integration of databases, providing the data necessary to address critical environmental challenges. Full integration across databases will require tackling the major impediments to data integration: taxonomic incompatibility, lags in data exchange, barriers to effective data synchronization, and isolation of individual initiatives.
- Published
- 2022
28. Nitric Oxide Alleviates Submergence-Induced Maize Seedling Root Tip Cell Death
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Yaoqi Li, Qiong Nan, Yinai Liu, Sue Lin, Hao Ji, Da Sun, Libo Jin, and Renyi Peng
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Plant Science ,Agronomy and Crop Science - Published
- 2022
29. Exploring the influence of work values on millennial hospitality employees’ turnover intentions: an empirical assessment
- Author
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Yaoqi Li, Yaya Song, Yun Yang, and Tzung-Cheng (T.C.) Huan
- Subjects
Tourism, Leisure and Hospitality Management ,Geography, Planning and Development - Published
- 2022
30. Recovery experience of wellness tourism and place attachment: insights from feelings-as-information theory
- Author
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Mang He, Biqiang Liu, and Yaoqi Li
- Subjects
Tourism, Leisure and Hospitality Management - Abstract
Purpose This study, guided by the feelings-as-information theory, aims to explore the effect of recovery experience of wellness tourism (REWT) on place attachment, alongside an examination into the mediating role of self-perceived health and the moderating role of health goal salience. The research site was traced for two years to monitor the evolution of the proposed model during the COVID-19 pandemic. Design/methodology/approach The successive independent samples data (in 2020 and 2021, respectively) were collected in Shizhu county, China. Structural equation modeling (SEM) was used with a survey of 1,472 wellness tourists (N2020 = 494, N2021 = 978) to test research hypotheses empirically. Additionally, independent sample t-test and multi-group SEM analysis were used to compare the mean difference of variables and coefficients’ difference between 2020 and 2021. Findings This study reveals that REWT can increase self-perceived health, resulting in a positive influence on place attachment. By tracing the research site and comparing the successive independent samples data, we found a stronger recovery experience effect of wellness tourism on place attachment alongside a weaker effect on self-perceived health in 2021. The positive relationship between self-perceived health and place attachment is significantly strengthened when health goals are salient. Originality/value This study investigated the mechanism behind the formation of place attachment in the wellness tourism context and extended understanding on the dynamic nature of the REWTand ongoing evolving person-place relationship during the COVID-19 pandemic. This study also provided practical suggestions to benefit industry practitioners by enhancing current understanding of improving experience-based management in wellness destinations.
- Published
- 2022
31. Can beauty save service failures? The role of recovery employees’ physical attractiveness in the tourism industry
- Author
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Yaoqi Li, Chun Zhang, and Shujie Fang
- Subjects
Marketing - Published
- 2022
32. Inspiration and wellness tourism: the role of cognitive appraisal
- Author
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Biqiang Liu, Yaoqi Li, Anna Kralj, Brent Moyle, and Mang He
- Subjects
Marketing ,Tourism, Leisure and Hospitality Management - Published
- 2022
33. Celebrity endorsement in tourism: Attention, emotional arousal and familiarity
- Author
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Biqiang Liu, Brent Moyle, Anna Kralj, and Yaoqi Li
- Subjects
Strategy and Management ,Tourism, Leisure and Hospitality Management ,Transportation ,Development - Published
- 2023
34. PD-1/PD-L1 Interaction Upregulates YAP1 Expression in HepG2 Cells Through MAPK/ERK Pathway.
- Author
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Shenghao Li, Muwei Dai, Fang Wang, Liyuan Hao, Caixia Feng, Yansheng Jia, Yaoqi Li, Xichun Kang, Xiaoyu Hu, and Huimin Yan
- Subjects
PROGRAMMED cell death 1 receptors ,YAP signaling proteins ,PROGRAMMED death-ligand 1 ,CHIMERIC proteins ,T-cell exhaustion ,MITOGEN-activated protein kinases - Abstract
Background: Antibodies, which target programmed cell death protein-1 (PD-1) or its ligand programmed death ligand-1 (PD-L1), can rescue T cells from an exhausted state and resume their immune response to cancer cells. Clinically, the purpose of blocking the PD-1/PD-L1 signaling pathway is to induce immune cells to play an anti-tumor role. However, the effect of intertumor PD-1/PD-L1 signal blocking on tumor cells remains unclear. Methods: HepG2 cells were treated with DHA, IFN-γ, BSA, DDP, PD-1-Fc (1 μg/ml), IgG-Fc, nivolumab, or human IgG for 24 h, respectively. GEPIA, cBioPortal, and TIMER databases were used to analyze the correlation between YAP1, PD-1, and PD-L1 and ERK, ERK-5, JNK, and p38. Western blot was used to detect the expression of YAP1 and p-ERK. Results: GEPIA, cBioPortal, and TIMER databases analysis showed that YAP1 was positively correlated with ERK. After HepG2 cells were treated with PD98059 (ERK inhibitor), the expression of YAP1 was decreased. In this study, we investigated the inhibitory effect of PD98059 on PD-1/PD-L1 signaling. Our study found that PD-1-Fc (PD-1 fusion protein) promoted the expression of p-ERK/ERK and YAP1 in HepG2 cells. In contrast, nivolumab (PD-1 blocking antibody) reduced the expression of p-ERK/ERK and YAP1 in IFN-γ-pretreated HepG2 cells. In addition, the application of DHA also inhibited the expression of p-ERK/ERK to inhibit YAP1. Furthermore, treatment of HepG2 cells with DHA alone or DHA combined with cisplatin (DDP) both inhibited the expression of p-ERK/ERK and YAP1. Conclusions: These results suggested that PD-1/ PD-L1 interactions between tumor cells could promote the expression of ERK or YAP1 within tumors. Moreover, the conduction of PD-1/PD-L1 could be reversed using ERK inhibitors. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
35. Algorithmic approach to discrete fracture network flow modeling in consideration of realistic connections in large-scale fracture networks
- Author
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Qihua Zhang, Shan Dong, Yaoqi Liu, Junjie Huang, and Feng Xiong
- Subjects
Discrete fracture network (DFN) flow model ,Geometric algorithm ,Fracture flow ,Water-sealing effect ,Engineering geology. Rock mechanics. Soil mechanics. Underground construction ,TA703-712 - Abstract
Analyzing rock mass seepage using the discrete fracture network (DFN) flow model poses challenges when dealing with complex fracture networks. This paper presents a novel DFN flow model that incorporates the actual connections of large-scale fractures. Notably, this model efficiently manages over 20,000 fractures without necessitating adjustments to the DFN geometry. All geometric analyses, such as identifying connected fractures, dividing the two-dimensional domain into closed loops, triangulating arbitrary loops, and refining triangular elements, are fully automated. The analysis processes are comprehensively introduced, and core algorithms, along with their pseudo-codes, are outlined and explained to assist readers in their programming endeavors. The accuracy of geometric analyses is validated through topological graphs representing the connection relationships between fractures. In practical application, the proposed model is employed to assess the water-sealing effectiveness of an underground storage cavern project. The analysis results indicate that the existing design scheme can effectively prevent the stored oil from leaking in the presence of both dense and sparse fractures. Furthermore, following extensive modification and optimization, the scale and precision of model computation suggest that the proposed model and developed codes can meet the requirements of engineering applications.
- Published
- 2024
- Full Text
- View/download PDF
36. Beauty premium or beauty penalty in sharing accommodation situations based on lay theories
- Author
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Yaoqi Li, Lixin Peng, Shuang Ma, and Xiaoman Zhou
- Subjects
Tourism, Leisure and Hospitality Management - Abstract
PurposeLimited research has paid attention to the physical attractiveness stereotype in peer-to-peer sharing accommodation settings. Since the high-risk situations in sharing accommodations, this paper aims to exam whether beauty premium is still relevant in peer-to-peer (P2P) accommodation.Design/methodology/approachThe mixed method, including 2,506 secondary data analysis and two scenario experiments, is carried out to test the research framework.FindingsThe results show that both beauty premium and beauty penalty exist in the e-commerce context. Excessively high attractiveness and plain looking of hosts are likely to decrease consumers’ booking decision while moderately attractive hosts will stimulate more booking behaviors. Moreover, perceived trustworthiness mediates the effect of physical attractiveness on booking decision. Additionally, similarity between hosts and consumers plays a moderating role in the relationship between physical attractiveness and perceived trustworthiness.Research limitations/implicationsThis study reveals the physical attractiveness stereotype effects in P2P accommodation and carry implications to P2P platforms and hosts for providing moderately attractive profile photos, enhancing trustworthiness and similarity between hosts and consumers. Further studies can investigate the robustness of the findings as well as more possible reasons for its occurrence.Originality/valueThe research provides a clearer understanding of physical attractiveness stereotype effect in peer-to-peer sharing accommodation platforms. Besides, the linkage between physical attractiveness and perceived trustworthiness is dynamic; a high host – consumer similarity weakens the negative impact of both excessively high attractiveness and plain looking on consumers’ perceived trustworthiness.
- Published
- 2021
37. Why do hotel interns stay in the hospitality and tourism industry? An interactionist perspective of organizational socialization
- Author
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Xiaoman Zhou, Yaou Hu, Yaoqi Li, and Biyan Wen
- Subjects
Tourism, Leisure and Hospitality Management - Abstract
PurposePromoting interns’ organizational socialization has become an urgent concern for the hotel industry. Building on career construction theory, this study aims to use a time-lagged design to investigate the interrelationships among perceived organizational support (POS), psychological capital and organizational socialization and their consequent effects on interns’ intention to stay in the hotel industry.Design/methodology/approachPanel data were obtained in three waves from hotel interns from 21 upscale hotels located in 13 cities in China with a time lag of 10 weeks (N= 369). The structural equation modeling was used for data analysis.FindingsPOS has a significantly positive effect on interns' psychological capital. Additionally, both POS and psychological capital contribute to the intention to stay in the hotel industry through the mediation of organizational socialization.Practical implicationsHotels should communicate with interns more explicitly, provide assistance programs to alleviate uncertainty and reward interns on their excellent service performance to improve POS. Moreover, setting up psychological capital programs and empowering interns to be involved in task development is beneficial for enhancing psychological capital. Hotels should also consider mentoring as a socialization approach. Further, career planning and counseling programs should be provided for interns’ long-term hospitality career development.Originality/valueA time-lagged research method is adopted to provide a new approach to improve interns’ intention to stay in the hotel industry from the interactionist perspective. This study enriches research about psychological capital, POS and organizational socialization.
- Published
- 2021
38. Customers’ self-image congruity and brand preference: a moderated mediation model of self-brand connection and self-motivation
- Author
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Yaoqi Li, Chun Zhang, Lori Shelby, and Tzung-Cheng Huan
- Subjects
Marketing ,Moderated mediation ,Brand preference ,Management of Technology and Innovation ,media_common.quotation_subject ,Self-brand ,Self motivation ,Psychology ,Social psychology ,Self-image ,Connection (mathematics) ,media_common - Abstract
Purpose This study aims to examine the moderated mediation model among self-image congruity, self-brand connection, self-motivation and brand preference and validate that actual and ideal self-image congruity are two distinct constructs. As shown in the conceptual model, actual and ideal self-image congruity toward a brand have direct and indirect positive effects on brand preference through self-brand connection, whereas self-motivation moderates the effect of self-image congruity on self-brand connection. Design/methodology/approach Data collection was done through mall intercepts in six shopping malls in Guangzhou, Zhuhai and Huizhou in southern China. In total, 461 usable questionnaires were collected with 500 distributed copies. Confirmatory factor analysis using Mplus (v.7) was done to assess the measurement validity for each construct. PROCESS analysis for SPSS (v.19.0.0) was used for hypothesis testing. Findings Both actual and ideal self-image congruities present significant positive effects on brand preference through self-brand connection. The relationship between self-image congruity and the self-brand connection is also moderated by self-motivation. Originality/value This study fills an existing literature gap by distinguishing self-image and ideal self-image congruity as distinct constructs. Self-brand connection is posited as a new way to understand the mechanism of the self-image congruity effect on brand preference. Samples from several shopping malls in southern China are used to justify the important moderating role of self-motivation in consumers’ brand preferences.
- Published
- 2021
39. Multiplicity on Limit Cycles of 3D Lotka-Volterra Competitive Systems
- Author
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Yaoqi Li and Jifa Jiang
- Subjects
Analysis - Published
- 2022
40. pH-Activatable Copper-Biomineralized Proenzyme for Synergistic Chemodynamic/Chemo-Immunotherapy against Aggressive Cancers
- Author
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Ting Li, Ying Zhang, Jie Zhu, Fangrui Zhang, An'an Xu, Tian Zhou, Yaoqi Li, Ming Liu, Hengte Ke, Tao Yang, Yong'an Tang, Jing Tao, Liyan Miao, Yibin Deng, and Huabing Chen
- Subjects
Mechanics of Materials ,Mechanical Engineering ,General Materials Science - Abstract
Artificial enzymes have demonstrated therapeutic benefit against diverse malignant tumors, yet their antitumor potencies are still severely compromised by non-selective catalysis, low atomic utilization efficiency, and undesired off-target toxicity. Herein, we report that the peroxidase-like biomineralized copper (II) carbonate hydroxide nanocrystals inside single albumin nanocages (CuCH-NCs) act as a pH-activatable proenzyme to achieve tumor-selective and synergistic chemodynamic/chemo-immunotherapy against aggressive triple-negative breast cancers (TNBCs). These CuCH-NCs show pH-sensitive Cu
- Published
- 2022
41. Existence of Two Limit Cycles in Zeeman’s Class 30 for 3D Lotka-Volterra Competitive System
- Author
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Yaoqi Li
- Subjects
General Earth and Planetary Sciences ,General Environmental Science - Published
- 2022
42. Towards an understanding of the latitudinal patterns in thermal tolerance and vulnerability of woody plants under climate warming
- Author
-
Xiaoling Zhang, Yaoqi Li, Shijia Peng, Zhiheng Wang, Tong Lyu, and Yunpeng Liu
- Subjects
Habitat suitability ,Ecology ,Global warming ,Vulnerability ,Environmental science ,Realized niche width ,Ecology, Evolution, Behavior and Systematics ,Woody plant - Published
- 2021
43. Phylogenetic niche conservatism and variations in species diversity–climate relationships
- Author
-
Xiaoling Zhang, Xiaoting Xu, Ke Jiang, Dongting Zou, Zhiheng Wang, Xiangyan Su, Yaoqi Li, Qinggang Wang, Ao Luo, Hongyu Cai, and Nawal Shrestha
- Subjects
Climatic gradient ,Ecology ,Phylogenetic niche conservatism ,Species diversity ,Biology ,Ecology, Evolution, Behavior and Systematics - Published
- 2021
44. Conservation of woody species in China under future climate and land‐cover changes
- Author
-
Shijia Peng, Yaoqi Li, Xiaoling Zhang, Zhiheng Wang, Yunpeng Liu, and Jian Zhang
- Subjects
Phylogenetic diversity ,Geography ,Ecology ,Agroforestry ,Land cover ,Future climate ,China ,Protected area - Published
- 2021
45. Global patterns of species richness of the holarctic alpine herb Saxifraga: the role of temperature and habitat heterogeneity
- Author
-
Qinggang Wang, Jianquan Liu, Xiaoting Xu, Dimitar Dimitrov, Yunpeng Liu, Nawal Shrestha, Lian Liu, Hong Chang, Yaoqi Li, Jianyong Wu, Xiangyan Su, Zhiheng Wang, Danilo M. Neves, and Lei Zhang
- Subjects
food.ingredient ,food ,Holarctic ,Ecology ,biology ,Herb ,Saxifraga ,Plant Science ,Species richness ,biology.organism_classification ,Ecology, Evolution, Behavior and Systematics ,Spatial heterogeneity - Abstract
The effects of contemporary climate, habitat heterogeneity and long-term climate change on species richness are well studied for woody plants in forest ecosystems, but poorly understood for herbaceous plants, especially in alpine–arctic ecosystems. Here, we aim to test if the previously proposed hypothesis based on the richness–environment relationship could explain the variation in richness patterns of the typical alpine–arctic herbaceous genus Saxifraga. Using a newly compiled distribution database of 437 Saxifraga species, we estimated the species richness patterns for all species, narrow- and wide-ranged species. We used generalized linear models and simultaneous autoregressive models to evaluate the effects of contemporary climate, habitat heterogeneity and historical climate on species richness patterns. Partial regressions were used to determine the independent and shared effects of different variables. Four widely used models were tested to identify their predictive power in explaining patterns of species richness. We found that temperature was negatively correlated with the richness patterns of all and wide-ranged species, and that was the most important environmental factor, indicating a strong conservatism of its ancestral temperate niche. Habitat heterogeneity and long-term climate change were the best predictors of the spatial variation of narrow-ranged species richness. Overall, the combined model containing five predictors can explain ca. 40%–50% of the variation in species richness. We further argued that additional evolutionary and biogeographical processes might have also played an essential role in shaping the Saxifraga diversity patterns and should be considered in future studies.
- Published
- 2021
46. Stay passionate and carry on: Why passion exhausts and how it can be restored
- Author
-
Hui Fu, Xiong-Hui Xiao, Ben Haobin Ye, Shujie Fang, Yaoqi Li, and Yingyu Wu
- Subjects
General Psychology - Published
- 2022
47. Anthropogenic vulnerability assessment of global terrestrial protected areas with a new framework
- Author
-
Jiahui Meng, Yaoqi Li, Yuhao Feng, Fangyuan Hua, Xiaoli Shen, Sheng Li, Nawal Shrestha, Shijia Peng, Carsten Rahbek, and Zhiheng Wang
- Subjects
Ecology, Evolution, Behavior and Systematics ,Nature and Landscape Conservation - Published
- 2023
48. Global distribution and evolutionary transitions of angiosperm sexual systems
- Author
-
Yunpeng Liu, Tong Lyu, Yichao Li, Ao Luo, Dimitar Dimitrov, Robert P. Freckleton, Yaoqi Li, Xiangyan Su, Qingjun Li, Xiaoting Xu, D. V. Sandanov, Yunyun Wang, Zhiheng Wang, Shuguang Liu, and Zhanqing Hao
- Subjects
0106 biological sciences ,End point ,Ecology ,Reproduction ,010604 marine biology & hydrobiology ,Biogeography ,Dioecy ,Climate change ,Plants ,Biology ,Evolutionary transitions ,Biological Evolution ,010603 evolutionary biology ,01 natural sciences ,Magnoliopsida ,Global distribution ,Ecology, Evolution, Behavior and Systematics ,Plant diversity - Abstract
Angiosperm sexual systems are fundamental to the evolution and distribution of plant diversity, yet spatiotemporal patterns in angiosperm sexual systems and their drivers remain poorly known. Using data on sexual systems and distributions of 68453 angiosperm species, we present the first global maps of sexual system frequencies and evaluate sexual system evolution during the Cenozoic. Frequencies of dioecy and monoecy increase with latitude, while hermaphrodites are more frequent in warm and arid regions. Transitions to dioecy from other states were higher than to hermaphroditism, but transitions away from dioecy increased since the Cenozoic, suggesting that dioecy is not an evolutionary end point. Transitions between hermaphroditism and dioecy increased, while transitions to monoecy decreased with paleo-temperature when paleo-temperature >0℃. Our study demonstrates the biogeography of angiosperm sexual systems from a macroecological perspective, and enhances our understanding of plant diversity patterns and their response to climate change. acceptedVersion
- Published
- 2021
49. Redemption of travelers’ spoiled identity in a time of health crisis: The role of empathy and social distance
- Author
-
Mang He, Yaoqi Li, and Biqiang Liu
- Subjects
Social stigma ,Social distance ,media_common.quotation_subject ,Identity (social science) ,Stigma (botany) ,Questionnaire ,Empathy ,Tourism, Leisure and Hospitality Management ,Social identity theory ,Psychology ,human activities ,Social psychology ,Tourism ,media_common - Abstract
One consequence of an epidemic is the attachment of a spoiled identity to travelers from pandemic areas (hereafter referred to as “travelers”), resulting in severe damage to their psychological health. Guided by the stigmatization process model, this study examines the impact of tourism practitioners' perceptions of illness labeling toward travelers, social identification with travelers, and effects of spatial stigma. The moderating effects of empathy and social distance on this relationship are also analyzed. The results of a questionnaire survey of 754 tourism practitioners showed that illness labeling toward travelers negatively influences social identity with travelers and this leads to spatial stigma. Tourism practitioners’ empathy and the social distance between them and travelers are found to moderate the relationship between illness labeling toward travelers and spatial stigma. Finally, this study further finds that the two moderators are found to be more effective in alleviating social stigma than moral stigma.
- Published
- 2021
50. Advances in FGFs for diabetes care applications
- Author
-
Yinai Liu, Qianqian Chen, Yaoqi Li, Liuliu Bi, Zhiying He, Chuxiao Shao, Libo Jin, Renyi Peng, and Xingxing Zhang
- Subjects
Blood Glucose ,Fibroblast Growth Factors ,Hyperglycemia ,Diabetes Mellitus ,Humans ,Insulin ,General Medicine ,General Pharmacology, Toxicology and Pharmaceutics ,General Biochemistry, Genetics and Molecular Biology - Abstract
Diabetes mellitus (DM) is an endocrine and metabolic disease caused by a variety of pathogenic factors, including genetic factors, environmental factors and behavior. In recent decades, the number of cases and the prevalence of diabetes have steadily increased, and it has become one of the most threatening diseases to human health in the world. Currently, insulin is the most effective and direct way to control hyperglycemia for diabetes treatment at a low cost. However, hypoglycemia is often a common complication of insulin treatment. Moreover, with the extension of treatment time, insulin resistance, considered the typical adverse symptom, can appear. Therefore, it is urgent to develop new targets and more effective and safer drugs for diabetes treatment to avoid adverse reactions and the insulin tolerance of traditional hypoglycemic drugs.In recent years, it has been found that some fibroblast growth factors (FGFs), including FGF1, FGF19 and FGF21, can safely and effectively reduce hyperglycemia and have the potential to be developed as new drugs for the treatment of diabetes. FGF23 is also closely related to diabetes and its complications, which provides a new approach for regulating blood glucose and solving the problem of insulin tolerance.This article reviews the research progress on the physiology and pharmacology of fibroblast growth factor in the treatment of diabetes. We focus on the application of FGFs in diabetes care and prevention.
- Published
- 2022
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