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3 results on '"Yaoguang Lv"'

1. A comparative analysis of NLRP3-related inflammatory mediators in synovial fluid in temporomandibular joint osteoarthritis and internal derangement

Author

Mengying Jia, Yaoguang Lv, Yingjie Xu, and Zhongcheng Gong

Subjects
Condylar degeneration, Temporomandibular joint osteoarthritis, NLRP3, Hyaluronic acid, Diseases of the musculoskeletal system, RC925-935
Abstract

Abstract Background The nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 (NLRP3) inflammasome signaling pathway is a highlighted topic in the field of inflammation. However, there is little research on the relationship between the NLRP3 inflammasome pathway and temporomandibular joint osteoarthritis (TMJOA). The aim of this study was to examine the expression of inflammatory mediators related to the NLRP3 inflammasome in the synovial fluid of patients with condylar cartilage degeneration and verify the clinical effects of sodium hyaluronic acid (HA) treatment on TMJOA. Methods Patients diagnosed with temporomandibular joint internal derangement (TMJID) without condylar defects and TMJOA with condylar defects were divided into two groups. There were thirty patients in each group, and inflammatory mediators related to the NLRP3 inflammasome, including interleukin-1 beta (IL-1β), IL-18, NLRP3, and cysteinyl aspartate specific proteinase 1 (CASP1), in synovial fluid were measured by enzyme-linked immunosorbent assay (ELISA). Eighteen patients in the TMJOA group were retested after two HA treatments to evaluate the therapeutic effects of HA. Results IL-1β, IL-18, NLRP3 and CASP1 were all positive in the two groups, and TMJOA patients with condylar defects had higher expression of these molecules than TMJID patients (P

Published
2021
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2. Pyroptosis Related Molecules are Significant for Cartilage Degeneration

Author

Mengying Jia, Yaoguang Lv, Zhoncheng Gong, and Yingjie Xu

Subjects
Chemistry, Pyroptosis, Cartilage degeneration, Cell biology
Abstract

Background: Pyroptosis is the highlight topic in inflammation. However, there is rarely research on relationship between pyroptosis and temporomandibular joint osteoarthritis (TMJOA), The aim of this study is to explore whether pyroptosis related molecules are significant for condylar cartilage degeneration and to verify the clinical effects of sodium hyaluronic acid (HA) treatment on TMJOA.Methods: Patients diagnosed as temporomandibular joint internal derangement (TMJID) without condylar defect and TMJOA with condylar defect were divided into two groups. Thirty patients in each group, and they were tested for pyroptosis related molecules via synovial fluid included interleukin-1beta (IL-1β), IL-18, nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 (NLRP3), cysteinyl aspartate specific proteinase 1 (CASP1) with Enzyme-linked immunosorbent assay（Elisa）. Eighteen cases in TMJOA group were tested again after twice HA treatment to evaluate HA’s therapeutic effects. Results: IL-1β, IL-18, NLRP3 and CASP1 were all positive in two groups, TMJOA patients with condylar defect had higher expressions of above molecules compared with TMJID patients (P＜0.05). IL-1β, IL-18, NLRP3 were decreased with twice HA therapy (P＜0.05), there was no significant difference in CASP1 with twice HA injections (P=0.549). Conclusions: Cell pyroptosis may be involved in condylar degeneration. HA could reduce part of pyroptosis molecules to relieve inflammation.

Published
2020
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3. Surface plasmon polariton propagation and combination in Y-shaped metallic channels

Author

Xiangdi Lin, Chunlei Du, Yaoguang Lv, Xiangang Luo, Hongtao Gao, Hanmin Yao, Changtao Wang, Haofei Shi, and Qiling Deng

Subjects
Materials science, Computer simulation, business.industry, Scattering, Surface plasmon, Finite-difference time-domain method, Physics::Optics, Resonance, Extraordinary optical transmission, Surface plasmon polariton, Atomic and Molecular Physics, and Optics, Metal, Optics, visual_art, visual_art.visual_art_medium, Optoelectronics, business
Abstract

The propagation and combination of surface plasmon polaritons (SPPs) in Y- shaped metallic nanochannels are investigated numerically via finite difference time domain (FDTD). It is shown that the behavior of SPPs in nano-size channels resembles that of light guiding in conventional waveguides, and SPPs can also be combined effectively with appropriately designed structures. The loss associated with metal absorption and scattering with the multiple reflections between slit openings on the bend angle are analyzed numerically. The Fabry-Perot cavity effect displayed by SPPs traveling in channels with finite length is discussed as well. (c) 2005 Optical Society of America.

Published
2009

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