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Your search keyword '"Yao, Yushuang"' showing total 17 results
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17 results on '"Yao, Yushuang"'

7. Design and FPGA Implementation of a Novel Efficient FRM-Based Channelized Receiver Structure

Author

Zhao Zhongkai, Junxi He, Wenxu Zhang, Yao Yushuang, and Wentong Zhao

Subjects
field programmable gate array, Frequency response masking, General Computer Science, business.industry, Computer science, General Engineering, Structure (category theory), Channelized, channelized receiver, narrow transition bandwidth, General Materials Science, lcsh:Electrical engineering. Electronics. Nuclear engineering, Field-programmable gate array, business, lcsh:TK1-9971, Computer hardware
Abstract

The main application of the filter bank in radar signal processing is the wideband digital channelized receiver. In order to save hardware resources of the field programmable gate array (FPGA), the efficient channelized receiver structure using polyphase filter has been designed. However, when the number of channels is greatly increased or the transition bandwidth of the filter bank (FB) becomes very narrow, it still consumes large amounts of hardware resources. Therefore, a novel efficient channelized receiver structure based on frequency response masking (FRM) and modulation filter bank is proposed in this paper. The proposed novel structure has less computational complexity in implementing FB with narrow transition bandwidth (NTB). Compared with other efficient FRM-based structures, the proposed novel structure is more suitable for wideband digital channelization receiver. The proposed novel structure is verified correctly by Matlab simulation. The FPGA implementation of the polyphase channelized receiver structure and the proposed novel efficient FRM-based channelized receiver structure are completed by Xilinx System Generator. The result shows that the proposed novel efficient FRM-based channelized receiver structure can save 48.09% of the DSP48E1 hardware resources compared with the polyphase channelized receiver structure and has low group delay characteristic.

Published
2019

15. Novel triazole analogs of apigenin-7-methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial-mediated apoptosis.

Author

Qi, Yuyan, Ding, Zhaoxia, Yao, Yushuang, Ma, Dehua, Ren, Feifei, Yang, Hongjuan, and Chen, Aiping

Subjects
BAX protein, OVARIAN cancer, OVARIAN cancer treatment, CANCER cells, MITOCHONDRIAL membranes
Abstract

Ovarian cancer is one of the main causes of cancer-associated mortality across the world. Currently, ovarian cancer is mainly treated with chemotherapy. However, ovarian cancer is detected at advanced stages and chemotherapy has numerous side effects. In addition, the results of current chemotherapy on the treatment of ovarian cancer are less than satisfactory. Therefore, there is an urgent need to develop novel and more viable chemotherapeutic agents that can be used to treat ovarian cancer. The present study was designed to synthesize a series of novel triazole analogs of the bioactive apigenin-7-methyl ether to evaluate its anticancer activity against three human ovarian cancer cell lines. A total of eight novel triazole derivatives were synthesized and screened for their anticancer activity. Of all the derivatives, a derivative named 3d exhibited significant and dose-dependent anticancer activity against the SKOV3 ovarian cancer cell line. The IC50 of 3d was found to be 10 µM against the SKOV3 cancer cell line. It was also observed that 3d induced apoptosis in SKOV3 cancer cells through the accretion of reactive oxygen species and reduction in mitochondrial membrane potential. The molecule also modulated the expression of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein. Taken together, these results showed that the apigenein-7-methyl ether novel derivative 3d may prove an important lead molecule for the treatment of ovarian cancer. [ABSTRACT FROM AUTHOR]

Published
2019

17. Study of the effect of metformin on expression levels of TNF-α and IL-18 in animal models of polycystic ovary syndrome.

Author

Ding Z, Chen A, Yao Y, Wang X, Yan L, Cai H, and Sun H

Subjects
Animals, Carboxymethylcellulose Sodium, Disease Models, Animal, Down-Regulation, Estradiol blood, Estrous Cycle drug effects, Estrous Cycle physiology, Female, Follicle Stimulating Hormone blood, Letrozole, Luteinizing Hormone blood, Ovulation drug effects, Ovulation physiology, Polycystic Ovary Syndrome chemically induced, Polycystic Ovary Syndrome physiopathology, Rats, Testosterone blood, Hypoglycemic Agents pharmacology, Interleukin-18 blood, Metformin pharmacology, Polycystic Ovary Syndrome blood, Tumor Necrosis Factor-alpha blood
Published
2021
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