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ObjectiveTo explore the risk factors of stroke， and to provide reference for the prevention and health management of stroke.MethodsFrom February 2022 to March 2022， four community residents over 60 years old with stroke in Shanghai were randomly selected as the case group （n=100）， and non-stroke residents were selected as the control group （n=100）. The survey was in the form of questionnaires to record and compare the age， body mass index （BMI）， blood lipids， blood pressure-related indicators， family history of other diseases， living habits， mood and sleep conditions of all subjects. The value of predicting the incidence of stroke among the elderly in Shanghai community was analyzed by receiver operating characteristic （ROC）， and the influencing factors of stroke were analyzed by logistic model.ResultsBMI， hypertension， heart disease， diabetes， transient ischemic attack （TIA）， dyslipidemia， family history of stroke， smoking， lack of exercise or only light physical labor， SBP， DBP， TG levels were significantly higher in the case group （P

The novel orange‐red light‐emitting garnet‐type phosphors Li3Bi3Te2O12:xSm3+ (0.005 ≤ x ≤ 0.25) were first synthesized using the high‐temperature solid‐state reaction method. The phase structure was recorded with XRD. Raman spectroscopic analysis was conducted for the first time to extract detailed structural insights of the tellurate garnet Li3Bi3Te2O12:Sm3+. The characteristics of the obtained compounds were investigated, including particle morphology, elemental mapping, diffuse reflection spectra, excitation and emission spectra, thermal stability, chromaticity coordinates according to the Commission International del′Eclairage, and color purity. The Li3Bi3Te2O12:Sm3+ phosphor could be effectively excited by 406 nm irradiation, and four sharp peaks were presented. The dominant peaks are located at 613 and 653 nm, corresponding to the typical transition of Sm3+ ions at 4G5/2→6H7/2 and 4G5/2→6H9/2, respectively. The phosphors present a regular concentration quenching trend, with an optimum Sm3+ doping concentration of 0.02. Impressively, the product demonstrates remarkable thermal stability by maintaining an emission intensity of 93% at a working temperature of 423 K. Additionally, the thermal quenching temperature (T0.5) surpasses 480 K. The lighting performance of the white light‐emitting diode fabricated using Li3Bi3Te2O12:0.02Sm3+ phosphor has been found to be exceptional, characterized by a high color rendering index (Ra = 90) and a low correlated color temperature (CCT = 5122 K). The electroluminescent spectrum of the red light‐emitting diode device fabricated by Li3Bi3Te2O12:0.02Sm3+ overlapped well with the absorption spectra of the phytochromes, suggesting its potential for plant cultivation light source. In conclusion, considering all these photoluminescent properties mentioned above, Li3Bi3Te2O12:Sm3+ phosphor can be regarded as a promising material for daily illumination and plant cultivation LEDs. [ABSTRACT FROM AUTHOR]

A sequence of reddish‐orange emitting NaSrBi(1−x)TeO6:xSm3+ phosphors were successfully composited by a favorable solid‐phase chemical process. The sintering temperature is optimized as 850°C. NaSrBiTeO6 (NSBTO):Sm3+ samples were assigned to the cubic double‐perovskite structure, exhibiting the space group of Fm3¯$\bar{3}$m (225). Photoluminescence emission spectra display the main peaks at 562, 598, 645, and 705 nm at 404 nm excitation. Among them, the most intense emission peak is at 645 nm. The concentration‐quenching mechanism of Sm3+ follows the interaction between electric dipoles and quadrupoles. The asymmetric ratio (I(4G5/2‐6H9/2)/I(4G5/2‐6H5/2) of NSBTO:2 mol%Sm3+ phosphor is extracted as 4.96. The optimum NSBTO:2 mol%Sm3+ phosphor has excellent thermal stability with a remained emission intensity riches 93.61% (420 K). After testing with high‐pressure water steam at various periods, the phosphor remains chemically stable for moisture resistance. For the NSBTO:2 mol%Sm3+ phosphor, the satisfactory color purity and low correlated color temperature (CCT) are obtained with 99.9% and 1494 K, respectively. The electroluminescence spectra of the prepared red light emitting diode (LED) are in conformity with the phytochrome absorption spectra of chlorophyll a, chlorophyll b, PFR, and PR. The white light‐emitting diode (w‐LED) is also perfectly packaged, obtaining an efficient color rendering index (Ra) of 92.12 and CCT of 5553 K. These exceeding optical properties certified that NaSrBi(1−x)TeO6:xSm3+ demonstrates promising prospects and can be efficiently applied in horticultural LED applications. [ABSTRACT FROM AUTHOR]

Edwardsiella piscicida is an important fish pathogen with a broad host that causes substantial economic losses in the aquaculture industry. Ferric uptake regulator (Fur) is a global transcriptional regulator and contains two typical domains, the DNA-binding domain and dimerization domain. In a previous study, we obtained a mutant strain of full-length fur of E. piscicida, TX01Δfur, which displayed increased siderophore production and stress resistance factors and decreased pathogenicity. To further reveal the regulatory mechanism of Fur, the DNA-binding domain (N-terminal) of Fur was knocked out in this study and the mutant was named TX01Δfur2. We found that TX01Δfur2 displayed increased siderophore production and enhanced adversity tolerance, including a low pH, manganese, and high temperature stress, which was consistent with the phenotype of TX01Δfur. Contrary to TX01Δfur, whose virulence was weakened, TX01Δfur2 displayed an ascended invasion of nonphagocytic cells and enhanced destruction of phagocytes via inducing overpowering or uncontrollable pyroptosis, which was confirmed by the fact that TX01Δfur2 induced higher levels of cytotoxicity, IL-1β, and p10 in macrophages than TX01. More importantly, TX01Δfur2 displayed an increased global virulence to the host, which was confirmed by the result that TX01Δfur2 caused higher lethality outcomes for healthy tilapias than TX01. These results demonstrate that the mutation of the Fur N-terminal domain augments the resistance level against the stress and pathogenicity of E. piscicida, which is not dependent on the bacterial number in host cells or host tissues, although the capabilities of biofilm formation and the motility of TX01Δfur2 decline. These interesting findings provide a new insight into the functional analysis of Fur concerning the regulation of virulence in E. piscicida and prompt us to explore the subtle regulation mechanism of Fur in the future. [ABSTRACT FROM AUTHOR]

Bandgap‐tunable mixed‐halide perovskite materials have attracted considerable interest because of their indispensability as top counterparts in tandem solar cells. However, the soft and disordered lattice always suffers from severe phase segregation under illumination, which is particularly susceptible to residual lattice strain. Herein, we report a strain regulation strategy by using alkenamides terminated Ti3C2Tx MXenes as an additive into perovskite precursor. Apart from the role of a template for grain growth to obtain high‐quality films, the stretchable alkyl chain promotes lattice shrinkage or expansion to form an elastic grain boundary to eliminate the spatially distributed stain and shut down ion migration channels. As a result, the all‐inorganic perovskite solar cells based on CsPbIBr2 and CsPbI2Br halides achieve prolonged device stability under harsh conditions and the best power conversion efficiencies up to 11.06% and 14.30%, respectively. [ABSTRACT FROM AUTHOR]