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146 results on '"Yao, Kexin"'

11. Abnormalities in Electroencephalographic Microstates in Patients with Late-Life Depression

Author

Lao, Jingyi, primary, Zeng, Yijie, additional, Wu, Zhangying, additional, Lin, Gaohong, additional, Wang, Qiang, additional, Yang, Mingfeng, additional, Zhang, Si, additional, Xu, Danyan, additional, Zhang, Min, additional, Yao, Kexin, additional, Liang, Shuang, additional, Liu, Qin, additional, Li, Jiafu, additional, Zhong, Xiaomei, additional, and Ning, Yuping, additional

Published
2024
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14. Complement C3a/C3aR inhibition alleviates the formation of aortic aneurysm in Marfan syndrome mice.

Author

Zhang, Fan, Yao, Kexin, Liu, Yan, Zhou, Mei, Zhang, Yanhong, Hong, Shiyao, Wu, Jian, and Zhang, Congcong

Subjects
THORACIC aneurysms, ABDOMINAL aortic aneurysms, COMPLEMENT activation, AORTIC aneurysms, COMPLEMENT inhibition
Abstract

Mutations in fibrillin 1 (FBN1) is the main cause of Marfan syndrome (MFS) with thoracic aortic aneurysm (TAA) as the main complication. Activation of the complement system plays a key role in the formation of thoracic and abdominal aortic aneurysms. However, the role of the complement system in MFS-associated aortic aneurysms remains unclear. In this study, we observed increased levels of complement C3a and C5a in the plasma of MFS patients and mouse, and the increased deposition of the activated complement system product C3b/iC3b was also observed in the elastic fiber rupture zone of 3-month-old MFS mice. The expression of C3a receptor (C3aR) was increased in MFS aortas, and recombinant C3a promoted the expression of cytokines in macrophages. The administration of a C3aR antagonist (C3aRA) attenuated the development of thoracic aortic aneurysms in MFS mice. The increased inflammation response and matrix metalloproteinases activities were also attenuated by C3aRA treatment in MFS mice. Therefore, these findings indicate that the complement C3a/C3aR inhibition alleviates the formation of aortic aneurysm in Marfan syndrome mice. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Unravelling surface and interfacial structures of a metal-organic framework by transmission electron microscopy.

Author

Zhu, Yihan, Ciston, Jim, Zheng, Bin, Miao, Xiaohe, Czarnik, Cory, Pan, Yichang, Sougrat, Rachid, Lai, Zhiping, Hsiung, Chia-En, Yao, Kexin, Pinnau, Ingo, Pan, Ming, and Han, Yu

Subjects
Nanoscience & Nanotechnology
Abstract

Metal-organic frameworks (MOFs) are crystalline porous materials with designable topology, porosity and functionality, having promising applications in gas storage and separation, ion conduction and catalysis. It is challenging to observe MOFs with transmission electron microscopy (TEM) due to the extreme instability of MOFs upon electron beam irradiation. Here, we use a direct-detection electron-counting camera to acquire TEM images of the MOF ZIF-8 with an ultralow dose of 4.1 electrons per square ångström to retain the structural integrity. The obtained image involves structural information transferred up to 2.1 Å, allowing the resolution of individual atomic columns of Zn and organic linkers in the framework. Furthermore, TEM reveals important local structural features of ZIF-8 crystals that cannot be identified by diffraction techniques, including armchair-type surface terminations and coherent interfaces between assembled crystals. These observations allow us to understand how ZIF-8 crystals self-assemble and the subsequent influence of interfacial cavities on mass transport of guest molecules.

Published
2017

35. Tailoring interfacial microenvironment of palladium‐zeolite catalysts for the efficient low‐temperature hydrodeoxygenation of vanillin in water

Author

Ran, Jiansu, primary, Alfilfil, Lujain, additional, Li, Jingwei, additional, Yangcheng, Ruixue, additional, Liu, Zhaohui, additional, Wang, Qin, additional, Cui, Yuntong, additional, Cao, Tong, additional, Qiao, Min, additional, Yao, Kexin, additional, Zhang, Daliang, additional, and Wang, Jianjian, additional

Published
2022
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36. In Situ Synthesis of C-N@NiFe 2 O 4 @MXene/Ni Nanocomposites for Efficient Electromagnetic Wave Absorption at an Ultralow Thickness Level.

Author

Sun, Qing, Yang, Xin, Shu, Tie, Yang, Xianfeng, Qiao, Min, Wang, Dashuang, Liu, Zhaohui, Li, Xinghua, Rao, Jinsong, Zhang, Yuxin, Yang, Pingan, and Yao, Kexin

Subjects
ELECTROMAGNETIC wave absorption, MAGNETIC materials, NANOCOMPOSITE materials, DIELECTRIC properties, COMPOSITE materials
Abstract

Recently, the development of composite materials composed of magnetic materials and MXene has attracted significant attention. However, the thickness and microwave absorption performance of the composite is still barely satisfactory. In this work, the C-N@NiFe2O4@MXene/Ni nanocomposites were successfully synthesized in situ by hydrothermal and calcination methods. Benefiting from the introduction of the carbon-nitrogen(C-N) network structure, the overall dielectric properties are improved effectively, consequently reducing the thickness of the composite while maintaining excellent absorption performance. As a result, the minimum reflection loss of C-N@NiFe2O4@MXene/Ni can reach −50.51 dB at 17.3 GHz at an ultralow thickness of 1.5 mm, with an effective absorption bandwidth of 4.95 GHz (13.02–18 GHz). This research provides a novel strategy for materials to maintain good absorption performance at an ultralow thickness level. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Enhanced Electromagnetic Wave Absorption Properties of Ultrathin MnO2 Nanosheet-Decorated Spherical Flower-Shaped Carbonyl Iron Powder

Author

Qu, Zhengwei, primary, Wang, Yi, additional, Yang, Pingan, additional, Zheng, Wei, additional, Li, Nan, additional, Bai, Jingying, additional, Zhang, Youwei, additional, Li, Kailin, additional, Wang, Dashuang, additional, Liu, Zhaohui, additional, Yao, Kexin, additional, Li, Rui, additional, and Zhang, Yuxin, additional

Published
2021
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42. Microstructure, Electromagnetic Properties, and Microwave Absorption Mechanism of SiO 2 -MnO-Al 2 O 3 Based Manganese Ore Powder for Electromagnetic Protection.

Author

Cai, Rui, Zheng, Wei, Yang, Pingan, Rao, Jinsong, Huang, Xin, Wang, Dashuang, Du, Zhilan, Yao, Kexin, and Zhang, Yuxin

Subjects
ELECTROMAGNETIC wave absorption, MANGANESE ores, CONSTRUCTION materials, BRICKS, MICROWAVES, ABSORPTION, ELECTROMAGNETIC waves, MICROSTRUCTURE
Abstract

Considering the electromagnetic protection needs of important ground buildings, exploring the electromagnetic wave (EMW) absorption performance of manganese ore powder (MOP) building materials is an effective way to overcome its low added value and difficulty in popularizing. Here, choosing filling ratios commonly used in building materials such as autoclaved bricks, MOP/paraffin samples with 20%, 40%, and 60% mass fraction of MOP were prepared, and electromagnetic properties were analyzed at 2–18 GHz using the coaxial method. The results show that 60 wt% sample has the best absorption performance, with a minimum reflection loss (RLmin) value of −22.06 dB at 15.04 GHz, and the effective absorption bandwidth (EAB, RL < −10 dB) reaches 4.16 GHz at a 7.65 mm absorber thickness, covering most of the Ku-band region. The excellent microwave absorption performance of MOP is due to its multi-oxide forming multi-interface structure and rough surface, which can not only form abundant dipole and interfacial polarization under the action of EMW, but also reflect and scatter the incident EMW, prolong the transmission path, and enhanced the absorption of microwaves. This study demonstrates that MOP building materials can have excellent microwave absorption properties, thus becoming a new way to address harmful manganese residue; for example, autoclaved bricks, which can not only improve the added value of manganese residue building materials but also can be consumed on a large scale. It provides a new idea to solve the harm of manganese residue. [ABSTRACT FROM AUTHOR]

Published
2022
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43. Chlorine Vacancy Passivation in Mixed Halide Perovskite Quantum Dots by Organic Pseudohalides Enables Efficient Rec. 2020 Blue Light-Emitting Diodes

Author

Zheng, Xiaopeng, primary, Yuan, Shuai, additional, Liu, Jiakai, additional, Yin, Jun, additional, Yuan, Fanglong, additional, Shen, Wan-Shan, additional, Yao, Kexin, additional, Wei, Mingyang, additional, Zhou, Chun, additional, Song, Kepeng, additional, Zhang, Bin-Bin, additional, Lin, Yuanbao, additional, Hedhili, Mohamed Nejib, additional, Wehbe, Nimer, additional, Han, Yu, additional, Sun, Hong-Tao, additional, Lu, Zheng-Hong, additional, Anthopoulos, Thomas D., additional, Mohammed, Omar F., additional, Sargent, Edward H., additional, Liao, Liang-Sheng, additional, and Bakr, Osman M., additional

Published
2020
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44. Investigating the Origin of Enhanced C2+ Selectivity in Oxide-/Hydroxide-Derived Copper Electrodes during CO2 Electroreduction

Author

Lei, Qiong, primary, Zhu, Hui, additional, Song, Kepeng, additional, Wei, Nini, additional, Liu, Lingmei, additional, Zhang, Daliang, additional, Yin, Jun, additional, Dong, Xinglong, additional, Yao, Kexin, additional, Wang, Ning, additional, Li, Xinghua, additional, Davaasuren, Bambar, additional, Wang, Jianjian, additional, and Han, Yu, additional

Published
2020
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48. Efficient hydrogenolysis of fructose to 1,2-propanediol over bifunctional Ru-WOx-MgOycatalysts under mild reaction conditions via enhancing the chemoselective cleavage of C–C bonds

Author

Luo, Shuang, Shu, Tie, Mao, Min, Yu, Haijie, Zheng, Yuxin, Ding, Daqian, Liu, Lingmei, Yao, Kexin, and Wang, Jianjian

Abstract

The abundance of oxygen vacancies in Ru-WOx-MgOycatalyst facilitates the chemoselective cleavage of C-C bonds in fructose to generate active intermediates and ultimately enhances the production of 1,2-propanediol.

Published
2024
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49. The therapeutic efficacy of different configuration nano-polydopamine drug carrier systems with photothermal synergy against head and neck squamous cell carcinoma

Author

Guo, Yuhao, Li, Bo, Xie, Huixu, Wu, Chenzhou, Wang, Guixue, Yao, Kexin, and Li, Longjiang

Abstract

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignant tumor worldwide. Considering its special anatomical site and the progressive resistance to chemotherapy drugs, the development of more effective, minimally invasive and precise treatment methods is urgently needed. Nanomaterials, given their special properties, can be used as drug carrier systems to improve the therapeutic effect and reduce the adverse effects. The drug carrier systems with photothermal effect can promote the killing of cancer cells and help overcome drug resistance through heat stress. We selected dopamine, a simple raw material, and designed and synthesized three different configurations of nano-polydopamine (nPDA) nanomaterials, including nPDA balls, nPDA plates and porous nPDA balls. In addition to the self-polymerization and self-assembly, nPDA has high photothermal conversion efficiency and can be easily modified. Moreover, we loaded cisplatin into three different configurations of nPDA, creating nPDA-cis (the nano-drug carrier system with cisplatin), and comparatively studied the properties and antitumor effects of all the nPDA and nPDA-cis materials in vitroand nPDA-cis in vivo. We found that the photothermal effect of the nPDA-cis balls drug carrier system had synergistic effect with cisplatin, resulting in excellent antitumor effect and good clinical application prospects. The comparison of the three different configurations of drug carrier systems suggested the importance of optimizing the spatial configuration design and examining the physical and chemical properties in the future development of nano-drug carrier systems. In this study, we also noted the duality and complexity of the influences of heat stress on tumors in vitroand in vivo. The specific mechanisms and the synergy with chemotherapy and immunotherapy will be an important research direction in the future.

Published
2024
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