1. The Effects of topical viscous lignocaine 2% versus per-rectal diclofenac in early post-tonsillectomy pain in children
- Author
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Mat Sulaiman Zayuah, Abdullah Baharudin, Mohamad Zaini Rhendra Hardy, Wan Adnan Wan Aasim, Kamaruljan Hassan Shamsul, Yang Ai Suan, and Ismail Hashimah
- Subjects
Male ,medicine.medical_specialty ,Diclofenac ,Meperidine ,Normal diet ,Administration, Topical ,medicine.medical_treatment ,Analgesic ,law.invention ,Eating ,Randomized controlled trial ,Administration, Rectal ,law ,medicine ,Humans ,Anesthetics, Local ,Child ,Pain Measurement ,Tonsillectomy ,Pain, Postoperative ,business.industry ,Anti-Inflammatory Agents, Non-Steroidal ,Soft diet ,Lidocaine ,General Medicine ,Diclofenac Sodium ,Drug Utilization ,Surgery ,Analgesics, Opioid ,Pethidine ,Otorhinolaryngology ,Opioid ,Child, Preschool ,Anesthesia ,Pediatrics, Perinatology and Child Health ,Female ,business ,medicine.drug - Abstract
Introduction Tonsillectomy is frequently associated with postoperative pain of considerable duration, which is usually accompanied by the substantial consumption of both opioid and non-opioid analgesic such as NSAIDs and local anaesthetics. Objective The aim of this study was to evaluate the efficacy between 2% viscous lignocaine and sodium diclofenac based upon the visual analogue scores (VASs), consumption of pethidine 0.5 mg kg−1 as the rescue drug postoperatively and time taken to resume feeding. Methods 130 patients aged between 5 and 12 years old were randomly allocated into 2 groups to be given either 2% viscous lignocaine 4 mg kg−1 body weight topically post-tonsillectomy or sodium diclofenac 1 mg kg−1 per-rectal post-induction of anaesthesia. Postoperatively visual analogues score was done for 24 h, the amount of pethidine given and time when the patient start taking oral feeding of clear fluid, soft diet and normal diet were documented. Results There was no significant difference in the visual analogue scores in both groups, however the requirement of pethidine as the rescue drug postoperatively was significant 2 h post-tonsillectomy (p = 0.023) in viscous lignocaine group compared to sodium diclofenac. The time taken to resume oral feeding and soft diet was also significant in viscous lignocaine group (p = 0.016 and p = 0.007) whereas there was no significant in taking normal diet. Conclusion: We concluded that 2% viscous lignocaine applied topically post-tonsillectomy is comparable to sodium diclofenac per-rectal in providing analgesia and faster oral feeding.
- Published
- 2010