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1,992 results on '"Yang, Yanyan"'

3. Guided Diffusion for Fast Inverse Design of Density-based Mechanical Metamaterials

Author

Yang, Yanyan, Wang, Lili, Zhai, Xiaoya, Chen, Kai, Wu, Wenming, Zhao, Yunkai, Liu, Ligang, and Fu, Xiao-Ming

Subjects
Computer Science - Computational Engineering, Finance, and Science, Computer Science - Machine Learning
Abstract

Mechanical metamaterial is a synthetic material that can possess extraordinary physical characteristics, such as abnormal elasticity, stiffness, and stability, by carefully designing its internal structure. To make metamaterials contain delicate local structures with unique mechanical properties, it is a potential method to represent them through high-resolution voxels. However, it brings a substantial computational burden. To this end, this paper proposes a fast inverse design method, whose core is an advanced deep generative AI algorithm, to generate voxel-based mechanical metamaterials. Specifically, we use the self-conditioned diffusion model, capable of generating a microstructure with a resolution of $128^3$ to approach the specified homogenized tensor matrix in just 3 seconds. Accordingly, this rapid reverse design tool facilitates the exploration of extreme metamaterials, the sequence interpolation in metamaterials, and the generation of diverse microstructures for multi-scale design. This flexible and adaptive generative tool is of great value in structural engineering or other mechanical systems and can stimulate more subsequent research., Comment: 13 pages, 6 figures

Published
2024

14. Advances in Endoplasmic Reticulum Stress in Liver Diseases

Author

LI Chuan, WU Yunchong, YANG Yanyan, LU Tao, LIU Yujuan, LIN Shide

Subjects
liver disease, endoplasmic reticulum stress, unfolded protein reaction, cell apoptosis, inflammation, Medicine
Abstract

A large number of studies have confirmed that endoplasmic reticulum stress (ERS) is closely related to the development and progression of liver diseases, but the mechanism of the association between ERS and liver disease progression has not been clarified and needs to be further explored. Numerous studies have found that moderate ERS can activate the unfolded protein response (UPR) to protect cells, while severe or persistent ERS can induce apoptosis. Therefore, exploring the role of ERS in the pathogenesis of liver diseases may help to discover new therapeutic strategies. This paper describes the current research status and potential therapeutic strategies of ERS and UPR in various liver diseases.

Published
2024
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15. Improving Chinese Spelling Check by Character Pronunciation Prediction: The Effects of Adaptivity and Granularity

Author

Li, Jiahao, Wang, Quan, Mao, Zhendong, Guo, Junbo, Yang, Yanyan, and Zhang, Yongdong

Subjects
Computer Science - Computation and Language
Abstract

Chinese spelling check (CSC) is a fundamental NLP task that detects and corrects spelling errors in Chinese texts. As most of these spelling errors are caused by phonetic similarity, effectively modeling the pronunciation of Chinese characters is a key factor for CSC. In this paper, we consider introducing an auxiliary task of Chinese pronunciation prediction (CPP) to improve CSC, and, for the first time, systematically discuss the adaptivity and granularity of this auxiliary task. We propose SCOPE which builds on top of a shared encoder two parallel decoders, one for the primary CSC task and the other for a fine-grained auxiliary CPP task, with a novel adaptive weighting scheme to balance the two tasks. In addition, we design a delicate iterative correction strategy for further improvements during inference. Empirical evaluation shows that SCOPE achieves new state-of-the-art on three CSC benchmarks, demonstrating the effectiveness and superiority of the auxiliary CPP task. Comprehensive ablation studies further verify the positive effects of adaptivity and granularity of the task. Code and data used in this paper are publicly available at https://github.com/jiahaozhenbang/SCOPE., Comment: To appear at the main conference of EMNLP 2022

Published
2022

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