Search

Your search keyword '"Yang, Sung Yun"' showing total 43 results
Start Over Author "Yang, Sung Yun"
43 results on '"Yang, Sung Yun"'

5. Ultrathin Nanostructured Films of Hyaluronic Acid and Functionalized β-Cyclodextrin Polymer Suppress Bacterial Infection and Capsular Formation of Medical Silicone Implants

Author

Chau Nguyen, Thi Thuy, primary, Shin, Chung Min, additional, Lee, Su Jin, additional, Koh, Eun Seo, additional, Kwon, Hyeok Hee, additional, Park, Hyewon, additional, Kim, Dong Ho, additional, Choi, Chul Hee, additional, Oh, Sang-Ha, additional, Kim, Dong Woon, additional, and Yang, Sung Yun, additional

Published
2022
Full Text
View/download PDF

16. Injectable Chitosan Carrier for Demineralized Bone Matrix

Author

Kim, Yu Han, primary, Cho, Mi Hee, additional, Song, In Bum, additional, Hyun, Hoon, additional, Lee, Jung Won, additional, Kim, Moon Suk, additional, Seo, Seog Jin, additional, Kang, Ke Won, additional, Khang, Gil Son, additional, Yang, Sung Yun, additional, and Lee, Hai Bang, additional

Published
2007
Full Text
View/download PDF

21. Nano-Protrusive Gold Nanoparticle-Hybridized Polymer Thin Film as a Sensitive, Multipatternable, and Antifouling Biosensor Platform

Author

Lee, Jeong-Hoon, Park, Byung-Soo, Ghang, Hyun-Gu, Song, Hyunjoon, and Yang, Sung Yun

Abstract

Hybrid films consisting of anisotropic octahedral gold nanoparticles (AuNPs) and polymers had their surfaces functionalized and were immobilized on surface plasmon resonance (SPR) sensors for biomolecule detection. Specifically, carboxylated octahedral AuNPs (C-Oh-AuNPs) and poly(allylamine hydrochloride) (PAH) were assembled as ultrathin films by using a layer-by-layer process. The ionic strength generated from the functional groups of C-Oh-AuNP and PAH influenced the composition, its surface morphology, and the reactivity of the film toward further chemical reactions such as the synthesis of spherical AuNPs (S-AuNPs). We were thus able to control the size and the structure of the C-Oh-AuNP and S-AuNPs converted to nano-raspberry-shaped particles. This hierarchical AuNP hybrid film exhibits much more sensitive and stable detection of biomolecules than regular flat chip systems, and this result may be due to the SPR of the AuNP at its surface being able to markedly enhance the local optical field of the chip. The micropatterning of the hybrid coating was also studied by using a soft lithographic patterning method. We, in particular, worked on creating multiplex patterns having different combinations of shapes and fluorescent colors. We expect our hybrid coating system with multicode biomolecular arrays to be used as a powerful platform for biosensor applications.

Published
2024
Full Text
View/download PDF

24. Surface Functionalization by Bioactive Coating on Magnetic Nanoparticles for Bio-sensing Application.

Author

Jeong, Jong-Chan, Jang, Yoon-Hee, and Yang, Sung Yun

Subjects
MAGNETIC nanoparticles, MAGNETIC properties of nanoparticles, POLYELECTROLYTES, BIOMOLECULE analysis, POLYACRYLIC acid
Abstract

Magnetic nanoparticles (MNPs) have been drawing much technological interests in medical diagnostics and therapy. However, it remains a challenge reducing false signal arising from non-specific interactions. Here, we coated MNPs with polyelectrolyte multilayer (PEM) films by layer-by-layer deposition with poly(allylamine hydrochloride) and poly(acrylic acid). The polyelectrolytes multilayers film prevented irreversible coagulation of MNPs and could be used for conjugation of biomolecules on the MNPs. Furthermore, we also demonstrated a potential application of the PEM-coated MNPS into a microfluidic system. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

43. Rational design of cytophilic and cytophobic polyelectrolyte multilayer thin films.

Author

Mendelsohn JD, Yang SY, Hiller J, Hochbaum AI, and Rubner MF

Subjects
Acrylic Resins, Models, Molecular, Molecular Conformation, Polymethacrylic Acids, Spectrophotometry, Surface Properties, Drug Design, Electrolytes chemical synthesis, Electrolytes chemistry, Polymers chemical synthesis, Polymers chemistry
Abstract

Nanostructured polyelectrolyte multilayer thin films electrostatically assembled alternately from such polymers as poly(allylamine hydrochloride) (PAH) and poly(acrylic acid) (PAA) were investigated for their in vitro cell interactions. Not surprisingly, NR6WT cells, a highly adhesive murine fibroblast cell line, attached to many different multilayer combinations tested. However, PAH/PAA multilayers constructed at pH deposition conditions of 2.0/2.0 were completely bioinert. Analogous cell interactions were observed with PAH/poly(methacrylic acid) (PAH/PMA), PAH/sulfonated poly(styrene) (PAH/SPS), and poly(diallyldimethylammonium chloride)/SPS (PDAC/SPS) systems, thereby suggesting a general trend in the fibroblasts' response to multilayers. Specifically, highly ionically stitched films attracted cells, whereas weakly ionically cross-linked multilayers, which swell substantially in physiological conditions to present richly hydrated surfaces, resisted fibroblast attachment. Thus, by manipulating the multilayer pH or ionic strength assembly conditions or both, which in turn dictate the molecular architecture of the thin films, one may powerfully direct a single multilayer combination to be either cell adhesive or cell resistant.

Published
2003
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results