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This article, based on the Appraisal System, investigates British journalists’ different attitudes toward China and Vietnam in British news reports about the Dover migrant tragedy in 2000 and the Essex migrant tragedy in 2019. By analyzing affect resources in a newly built corpus with the help of UAM Corpus Tool 3.3, this study finds that more negative affect resources are used to portray China than those depicting Vietnam. British journalists manipulated emotions to emphasize that China, whether in 2000 or 2019, was a backward and underdeveloped country where citizens tried all means to escape to Britain. However, when British journalists found that the victims were Vietnamese instead of Chinese, they shifted attention to the pitiful Vietnamese families of the victims and tended to arouse readers’ sympathy. The corpus findings highlight the ideological contradiction between Britain and China, reveal Britain’s distrust of China’s system, and suggest that the different comprehensive national powers of China and Vietnam have different impacts on Britain’s international status, verifying that news discourse is permeated by ideology, politics, and economy.

Prostaglandin E2 (PGE2) has been implicated in hepatocellular carcinoma cell invasion. Recently, it was reported that Y box-binding protein 1 (YB-1) is closely correlated with malignancy. This study was designed to examine the mechanisms by which PGE2 increases YB-1 expression and promotes HCC cell invasion. PGE2 greatly enhanced HCC cell invasion through upregulation of the YB-1 protein, and the EP1 receptor is mainly responsible for this regulation. Src and EGFR were both activated by PGE2, which in turn increased the phosphorylation levels of p44/42 MAPK. Src, EGFR and p44/42 MAPK were all involved in PGE2-induced YB-1 expression. Chemical inhibitors and RNAi analysis all confirmed the role of mTOR complex 1 in YB-1 expression induced by PGE2. Furthermore, YB-1 was able to regulate the expression of a series of EMT-associated genes, which indicated that YB-1 could have the potential to control the epithelial-mesenchymal transition process in HCC cells. These findings reveal that PGE2 upregulated YB-1 expression through the EP1/Src/EGFR/p44/42 MAPK/mTOR pathway, which greatly enhanced HCC cell invasion. This study for the first time describes the mechanisms through which PGE2 regulates YB-1 expression and promotes HCC cell invasion.