Search

A six‐cyclic crown ether‐type pillar[5]arene was synthesized, and the five ethylene oxide loops were located outside the cavity and not affected by temperature changes which was confirmed by variable‐temperature NMR experiment in DMSO‐d6 and CDCl3 and 2D 1H−1H NOESY experiment in CDCl3. The six‐cyclic pillar[5]‐crown also showed greater binding ability of host‐guest with bis(pyridinium) derivatives than conventional alkoxy pillar[5]arenes that illustrated through 1H NMR titration spectroscopic experiment in acetone‐d6/CDCl3 (1 : 1) and UV‐vis titration experiments in CHCl3 at room temperature. The five benzocrown ethers at the periphery were able to bind metal cations by 1H NMR titration spectroscopic experiment in CD2Cl2/methanol‐d4(9 : 1). [ABSTRACT FROM AUTHOR]

Hand, foot and mouth disease (HFMD) is a widespread infectious disease that causes a significant disease burden on society. To achieve early intervention and to prevent outbreaks of disease, we propose a novel warning model that can accurately predict the incidence of HFMD. We propose a spatial-temporal graph convolutional network (STGCN) that combines spatial factors for surrounding cities with historical incidence over a certain time period to predict the future occurrence of HFMD in Guangdong and Shandong between 2011 and 2019. The 2011–2018 data served as the training and verification set, while data from 2019 served as the prediction set. Six important parameters were selected and verified in this model and the deviation was displayed by the root mean square error and the mean absolute error. As the first application using a STGCN for disease forecasting, we succeeded in accurately predicting the incidence of HFMD over a 12-week period at the prefecture level, especially for cities of significant concern. This model provides a novel approach for infectious disease prediction and may help health administrative departments implement effective control measures up to 3 months in advance, which may significantly reduce the morbidity associated with HFMD in the future. [ABSTRACT FROM AUTHOR]

A six-cyclic crown ether-type pillar[5]arene was synthesized, and the five ethylene oxide loops were located outside the cavity and not affected by temperature changes which was confirmed by variable-temperature NMR experiment in DMSO-d6 and CDCl 3 and 2D 1 H- 1 H NOESY experiment in CDCl 3 . The six-cyclic pillar[5]-crown also showed greater binding ability of host-guest with bis(pyridinium) derivatives than conventional alkoxy pillar[5]arenes that illustrated through 1 H NMR titration spectroscopic experiment in acetone-d6/CDCl 3 (1 : 1) and UV-vis titration experiments in CHCl 3 at room temperature. The five benzocrown ethers at the periphery were able to bind metal cations by 1 H NMR titration spectroscopic experiment in CD 2 Cl 2 /methanol-d4(9 : 1)., (© 2024 Wiley-VCH GmbH.)

Copper ions adsorption by beer yeast was studied by AAS, FTIR, SEM/EDS etc. The quantity of copper biosorption by NaOH-treated yeast and acetone-treated yeast increased significantly, while the esterification of carboxylate functionalities and the methylation of amino group presented in the cell walls of yeast resulted in a marked decrease in copper adsorption. These results show that amino and carboxylate groups in yeast cell wall play a great role in binding copper. According to IR spectra, the dominating bands near 1 652, 1 539 and 1 237 cm(-1) are assigned to amide I , amide II and amide IlI, the characteristic IR absorption of protein which could be one of the significant components of cell walls. The peak near 1 456 cm(-1) is attributable to the bending stretching of CH2- and CH3-. The changes in the spectra of the copper-exposed yeast biomass were in the stretch of hydroxyl groups or amino groups, which shifted from 3 392 to 3 404 cm' , and in the symmetrical stretch of carboxylate groups, which shifted from 1 405 to 1 383 cm(-1). The components and structure of the exposed-copper biomass remain intact. SEM/EDS analysis shows that the main elements of beer yeast are carbon, oxygen, and magnesium, while the surface of yeast is rough, and the copper-loaded yeast only binds little copper.