203,798 results on '"Yan, Y"'
Search Results
2. Interstellar Nitrogen Isotope Ratios: Measurements on tracers of C$^{14}$N and C$^{15}$N
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Chen, J. L., Zhang, J. S., Henkel, C., Yan, Y. T., Yu, H. Z., Wang, Y. X., Zou, Y. P., Zhao, J. Y., and Wang, X. Y.
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Astrophysics - Astrophysics of Galaxies - Abstract
The nitrogen isotope ratio 14N/15N is a powerful tool to trace Galactic stellar nucleosynthesis and constraining Galactic chemical evolution. Previous observations have found lower 14N/15N ratios in the Galactic center and higher values in the Galactic disk. This is consistent with the inside-out formation scenario of our Milky Way. However, previous studies mostly utilized double isotope ratios also including 12C/13C, which introduces additional uncertainties. Here we therefore present observations of C14N and its rare isotopologue, C15N, toward a sample of star forming regions, measured by the IRAM 30 m and/or the ARO 12 m telescope at $\lambda$ ~3 mm wavelength. For those 35 sources detected in both isotopologues, physical parameters are determined. Furthermore we have obtained nitrogen isotope ratios using the strongest hyperfine components of CN and C15N. For those sources showing small deviations from Local Thermodynamical Equilibrium and/or self-absorption, the weakest hyperfine component, likely free of the latter effect, was used to obtain reliable 14N/15N values. Our measured 14N/15N isotope ratios from C14N and C15N measurements are compatible with those from our earlier measurements of NH3 and 15NH3 (Paper I), i.e., increasing ratios to a Galacticentric distance of ~9 kpc. The unweighted second order polynomial fit yields $\frac{{\rm C^{14}N}}{{\rm C^{15}N}} = (-4.85 \pm 1.89)\;{\rm kpc^{-2}} \times R_{\rm GC}^{2} + (82.11 \pm 31.93) \;{\rm kpc^{-1}} \times R_{\rm GC} - (28.12 \pm 126.62)$. Toward the outer galaxy, the isotope ratio tends to decrease, supporting an earlier finding by H13CN/HC15N. Galactic chemical evolution models are consistent with our measurements of the 14N/15N isotope ratio, i.e. a rising trend from the Galactic center region to approximately 9 kpc, followed by a decreasing trend with increasing $R_{\rm GC}$ toward the outer Galaxy., Comment: 34 pages, 9 figures, 6 tables
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- 2024
3. An ALCHEMI inspection of sulphur-bearing species towards the central molecular zone of NGC 253
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Bouvier, M., Viti, S., Behrens, E., Butterworth, J., Huang, K. -Y., Mangum, J. G., Harada, N., Martín, S., Rivilla, V. M., Muller, S., Sakamoto, K., Yoshimura, Y., Tanaka, K., Nakanishi, K., Herrero-Illana, R., Colzi, L., Gorski, M. D., Henkel, C., Humire, P. K., Meier, D. S., van der Werf, P. P., and Yan, Y. T.
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Astrophysics - Astrophysics of Galaxies - Abstract
Sulphur-bearing species are detected in various environments within Galactic star-forming regions and are particularly abundant in the gas phase of outflows and shocks, and photo-dissociation regions. In this work, we aim to investigate the nature of the emission from the most common sulphur-bearing species observable at millimetre wavelengths towards the nuclear starburst of the galaxy NGC 253. We intend to understand which type of regions are probed by sulphur-bearing species and which process(es) dominate(s) the release of sulphur into the gas phase. We used the high-angular resolution (1.6" or 27 pc) observations from the ALCHEMI ALMA Large Program to image several sulphur-bearing species towards the central molecular zone (CMZ) of NGC 253. We performed local thermodynamic equilibrium (LTE) and non-LTE large velocity gradient (LVG) analyses to derive the physical conditions of the gas in which S-bearing species are emitted, and their abundance ratios across the CMZ. Finally, we compared our results with previous ALCHEMI studies and a few selected Galactic environments. We found that not all sulphur-bearing species trace the same type of gas: strong evidence indicates that H2S and part of the emission of OCS, H2CS, and SO, are tracing shocks whilst part of SO and CS emission rather trace the dense molecular gas. For some species, such as CCS and SO2, we could not firmly conclude on their origin of emission. The present analysis indicates that the emission from most sulphur-bearing species throughout the CMZ is likely dominated by shocks associated with ongoing star formation. In the inner part of the CMZ where the presence of super star clusters was previously indicated, we could not distinguish between shocks or thermal evaporation as the main process releasing the S-bearing species., Comment: 44 pages, 20 figures, Accepted for publication in A&A
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- 2024
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4. Search for solar axions by Primakoff effect with the full dataset of the CDEX-1B Experiment
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Yang, L. T., Liu, S. K., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, T., Guo, X. Y., He, L., He, J. R., Hu, J. W., Huang, H. X., Huang, T. C., Jiang, L., Karmakar, S., Li, H. B., Li, H. Y., Li, J. M., Li, J., Li, M. C., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, Y. D., Liu, Y., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Shen, M. B., Singh, M. K., Sun, T. X., Sun, W. L., Tang, C. J., Tian, Y., Wang, G. F., Wang, J. Z., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, Y. C., Xing, H. Y., Xiong, K. Z., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, P., Zhang, Z. H., Zhang, Z. Y., Zhao, J. Z., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
We present the first limit on $g_{A\gamma}$ coupling constant using the Bragg-Primakoff conversion based on an exposure of 1107.5 kg days of data from the CDEX-1B experiment at the China Jinping Underground Laboratory. The data are consistent with the null signal hypothesis, and no excess signals are observed. Limits of the coupling $g_{A\gamma}<2.08\times10^{-9}$ GeV$^{-1}$ (95\% C.L.) are derived for axions with mass up to 100 eV/$c^2$. Within the hadronic model of KSVZ, our results exclude axion mass $>5.3~\rm{eV}/c^2$ at 95\% C.L., Comment: 7 pages, 5 figures
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- 2024
5. Coherent Transfer of Lattice Entropy via Extreme Nonlinear Phononics in Metal Halide Perovskites
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Liu, Z., Shi, Y., Jiang, T., Luo, L., Huang, C., Mootz, M., Song, Z., Yan, Y., Yao, Y., Zhao, J., and Wang, J.
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Condensed Matter - Materials Science - Abstract
Entropy transfer in metal halide perovskites, characterized by significant lattice anharmonicity and low stiffness, underlies the remarkable properties observed in their optoelectronic applications, ranging from solar cells to lasers. The conventional view of this transfer involves stochastic processes occurring within a thermal bath of phonons, where lattice arrangement and energy flow from higher to lower frequency modes. Here we unveil a comprehensive chronological sequence detailing a conceptually distinct, coherent transfer of entropy in a prototypical perovskite CH$_3$NH$_3$Pbl$_3$. The terahertz periodic modulation imposes vibrational coherence into electronic states, leading to the emergence of mixed (vibronic) quantum beat between approximately 3 THz and 0.3 THz. We highlight a well-structured, bi-directional time-frequency transfer of these diverse phonon modes, each developing at different times and transitioning from high to low frequencies from 3 to 0.3 THz, before reversing direction and ascending to around 0.8 THz. First-principles molecular dynamics simulations disentangle a complex web of coherent phononic coupling pathways and identify the salient roles of the initial modes in shaping entropy evolution at later stages. Capitalizing on coherent entropy transfer and dynamic anharmonicity presents a compelling opportunity to exceed the fundamental thermodynamic (Shockley-Queisser) limit of photoconversion efficiency and to pioneer novel optoelectronic functionalities.
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- 2024
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6. First Search for Light Fermionic Dark Matter Absorption on Electrons Using Germanium Detector in CDEX-10 Experiment
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Liu, J. X., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, T., Guo, X. Y., He, L., He, J. R., Hu, J. W., Huang, H. X., Huang, T. C., Jiang, L., Karmakar, S., Li, H. B., Li, H. Y., Li, J. M., Li, J., Li, M. C., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Shen, M. B., Singh, M. K., Sun, T. X., Sun, W. L., Tang, C. J., Tian, Y., Wang, G. F., Wang, J. Z., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, Y. C., Xing, H. Y., Xiong, K. Z., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, P., Zhang, Z. H., Zhang, Z. Y., Zhao, J. Z., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
We present the first results of the search for sub-MeV fermionic dark matter absorbed by electron targets of Germanium using the 205.4~kg$\cdot$day data collected by the CDEX-10 experiment, with the analysis threshold of 160~eVee. No significant dark matter (DM) signals over the background are observed. Results are presented as limits on the cross section of DM--electron interaction. We present new constraints of cross section in the DM range of 0.1--10 keV/$c^2$ for vector and axial-vector interaction. The upper limit on the cross section is set to be $\rm 5.5\times10^{-46}~cm^2$ for vector interaction, and $\rm 1.8\times10^{-46}~cm^2$ for axial-vector interaction at DM mass of 5 keV/$c^2$., Comment: 6 pages, 4 figures
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- 2024
7. Polarized radio emission of RRAT J1854+0306
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Guo, Qi, Kong, Minzhi, Wang, P. F., Yan, Y., and Zhou, D. J.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Polarized radio emission of RRAT J1854+0306 is investigated with single pulses using Five-hundred-meter-Aperture Spherical Telescope. Its emission is characterized by nulls, narrow and weak pulses, and occasional wide and intense bursts with a nulling fraction of 53.2%. Its burst emission is typically of one rotation, and occasionally of two or three or even five rotations at the most, but without significant periodicity. The integrated pulse profile has an 'S'-shaped position angle curve that is superposed with orthogonal modes, from which geometry parameters are obtained. Individual pulses exhibit diverse profile morphology with single, double, or multiple peaks. The intensity and width of these pulses are highly correlated, and bright pulses generally have wide profiles with multiple peaks. These nulling behaviours, profile morphology, and polarization demonstrate that a rotating radio transient has the same physical origins as the normal pulsars., Comment: 9 pages,10 figures
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- 2024
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8. Constraints on the Blazar-Boosted Dark Matter from the CDEX-10 Experiment
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Xu, R., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, T., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jiang, L., Karmakar, S., Li, H. B., Li, H. Y., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Singh, M. K., Sun, T. X., Tang, C. J., Tian, Y., Wang, G. F., Wang, J. Z., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, J. Z., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
We report new constraints on light dark matter (DM) boosted by blazars using the 205.4 kg day data from the CDEX-10 experiment located at the China Jinping Underground Laboratory. Two representative blazars, TXS 0506+56 and BL Lacertae are studied. The results derived from TXS 0506+56 exclude DM-nucleon elastic scattering cross sections from $4.6\times 10^{-33}\ \rm cm^2$ to $1\times10^{-26}\ \rm cm^2$ for DM masses between 10 keV and 1 GeV, and the results derived from BL Lacertae exclude DM-nucleon elastic scattering cross sections from $2.4\times 10^{-34}\ \rm cm^2$ to $1\times10^{-26}\ \rm cm^2$ for the same range of DM masses. The constraints correspond to the best sensitivities among solid-state detector experiments in the sub-MeV mass range., Comment: 7 pages, 4 figures
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- 2024
9. Probing Dark Matter Particles from Evaporating Primordial Black Holes via Electron Scattering in the CDEX-10 Experiment
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Zhang, Z. H., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, T., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jiang, L., Karmakar, S., Li, H. B., Li, H. Y., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Singh, M. K., Sun, T. X., Tang, C. J., Tian, Y., Wang, G. F., Wang, J. Z., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. Y., Zhao, J. Z., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
Dark matter (DM) is a major constituent of the Universe. However, no definite evidence of DM particles (denoted as ``$\chi$") has been found in DM direct detection (DD) experiments to date. There is a novel concept of detecting $\chi$ from evaporating primordial black holes (PBHs). We search for $\chi$ emitted from PBHs by investigating their interaction with target electrons. The examined PBH masses range from 1$\times$10$^{15}$ to 7$\times$10$^{16}$ g under the current limits of PBH abundance $f_{PBH}$. Using 205.4 kg$\cdot$day data obtained from the CDEX-10 experiment conducted in the China Jinping Underground Laboratory, we exclude the $\chi$--electron ($\chi$--$e$) elastic-scattering cross section $\sigma_{\chi e} \sim 5\times10^{-29}$ cm$^2$ for $\chi$ with a mass $m_{\chi}\lesssim$ 0.1 keV from our results. With the higher radiation background but lower energy threshold (160 eV), CDEX-10 fill a part of the gap in the previous work. If ($m_{\chi}$, $\sigma_{\chi e}$) can be determined in the future, DD experiments are expected to impose strong constraints on $f_{PBH}$ for large $M_{PBH}$s., Comment: 9 pages, 6 figures, 3 tables. Version updated to match SCPMA version
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- 2024
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10. Discovery of widespread non-metastable ammonia masers in the Milky Way
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Yan, Y. T., Henkel, C., Menten, K. M., Wilson, T. L., Wootten, A., Gong, Y., Wyrowski, F., Yang, W., Brunthaler, A., Kraus, A., and Winkel, B.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present the results of a search for ammonia maser emission in 119 Galactic high-mass star-forming regions (HMSFRs) known to host 22 GHz H$_2$O maser emission. Our survey has led to the discovery of non-metastable NH$_3$ inversion line masers toward 14 of these sources. This doubles the number of known non-metastable ammonia masers in our Galaxy, including nine new very high excitation ($J,K$)~=~(9,6) maser sources. These maser lines, including NH$_3$ (5,4), (6,4), (6,5), (7,6), (8,6), (9,6), (9,8), (10,8), and (11,9), arise from energy levels of 342 K, 513 K, 465 K, 606 K, 834 K, 1090 K, 942 K, 1226 K, and 1449 K above the ground state. Additionally, we tentatively report a new metastable NH$_3$ (3,3) maser in G048.49 and an NH$_3$ (7,7) maser in G029.95. Our observations reveal that all of the newly detected NH$_3$ maser lines exhibit either blueshifted or redshifted velocities with respect to the source systemic velocities. Among the non-metastable ammonia maser lines, larger velocity distributions, offset from the source systemic velocities, are found in the ortho-NH$_3$ ($K=3n$) than in the para-NH$_3$ ($K\neq3n$) transitions., Comment: 14 pages, 4 tables, 9 figures. Accepted for publication in A&A
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- 2024
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11. The FAST Galactic Plane Pulsar Snapshot Survey -- V. PSR J1901+0658 in a double neutron star system
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Su, W. Q., Han, J. L., Yang, Z. L., Wang, P. F., Yuan, J. P., Wang, C., Zhou, D. J., Wang, T., Yan, Y., Jing, W. C., Cai, N. N., Xie, L., Xu, J., Wang, H. G., Xu, R. X., and You, X. P.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Double neutron star (DNS) systems offer excellent opportunities to test gravity theories. We report the timing results of PSR J1901+0658, the first pulsar discovered in the FAST Galactic Plane Pulsar Snapshot (GPPS) Survey. Based on timing observations by FAST over 5 yr, we obtain the phase-coherent timing solutions and derive the precise measurements of its position, spin parameters, orbital parameters, and dispersion measure. It has a period of 75.7 ms, a period derivative of 2.169(6)$\times 10^{-19}$ s s$^{-1}$, and a characteristic age of 5.5 Gyr. This pulsar is in an orbit with a period of 14.45 d and an eccentricity of 0.366. One post-Keplerian parameter, periastron advance, has been well-measured as being 0.00531(9) deg yr$^{-1}$, from which the total mass of this system is derived to be 2.79(7) M$_{\odot}$. The pulsar has the mass upper limit of 1.68 M$_{\odot}$, so the lower limit for the companion mass is 1.11 M$_{\odot}$. Because PSR J1901+0658 is a partially recycled pulsar in an eccentric binary orbit with such a large companion mass, it should be in a DNS system according to the evolution history of the binary system., Comment: 6 pages, 6 figures
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- 2024
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12. Molecular isotopologue measurements toward super star clusters and the relation to their ages in NGC253 with ALCHEMI
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Butterworth, J., Viti, S., Van der Werf, P. P., Mangum, J. G., Martín, S., Harada, N., Emig, K. L., Muller, S., Sakamoto, K., Yoshimura, Y., Tanaka, K., Herrero-Illana, R., Colzi, L., Rivilla, V. M., Huang, K. Y., Bouvier, M., Behrens, E., Henkel, C., Yan, Y. T., Meier, D. S., and Zhou, D.
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Astrophysics - Astrophysics of Galaxies - Abstract
Determining the evolution of the CNO isotopes in the interstellar medium (ISM) of starburst galaxies can yield important constraints on the ages of superstar clusters (SSCs), or on other aspects and contributing factors of their evolution. Due to the time-dependent nature of the abundances of isotopes within the ISM as they are supplied from processes such as nucleosynthesis or chemical fractionation, this provides the possible opportunity to probe the ability of isotopes ratios to trace the ages of high star forming regions, such as SSCs. The goal of this study is to investigate whether the isotopic variations in SSC regions within NGC253 are correlated with their different ages as derived from stellar population modelling. We have measured abundance ratios of CO, HCN and HCO$^+$ isotopologues in six regions containing SSCs within NGC253 using high spatial resolution (1.6",$\sim 28$pc) data from the ALCHEMI (ALma Comprehensive High-resolution Extragalactic Molecular Inventory) ALMA Large program. We have then analysed these ratios using RADEX radiative transfer modelling, with the parameter space sampled using the nested sampling Monte Carlo algorithm MLFriends. These abundance ratios were then compared to ages predicted in each region via the fitting of observed star formation tracers (such as Br$\gamma$) to starburst stellar population evolution models. We do not find any significant trend with age for the CO and HCN isotopologue ratios on the timescales for the ages of the SSC* regions observed. The driving factors of these ratios within SSCs could be the Initial Mass Function as well as possibly fractionation effects. To further probe these effects in SSCs over time a larger sample of SSCs must be observed spanning a larger age range., Comment: 44 pages, 43 Figures, Accepted for Publication to A&A
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- 2024
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13. A Novel Multiple-Network Analysis Integrating Metabolomics and Pharmacology for Mechanism Study of Medicine: A Case Study of CDD-2101 Against Constipation
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Shi, Jingchun, Xiang, Li, Lam, Yan Y., Ning, Ziwan, Liu, Jie, Li, Yaqi, Zhou, Yujuan, Zhai, Lixiang, Lin, Chengyuan, Zhu, Lin, and Bian, Zhaoxiang
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- 2024
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14. Self-Assembling Ceramide 2-Cyclodextrin Inclusion Nanoparticles for Corneal Repair
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Yan, Y. T., Liu, L., Lin, X. F., Wei, Y. X., Ren, H. H., Wang, W., He, X. J., Li, X. M., and Liu, E. G.
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- 2024
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15. Inclined Crack Quantification of Plate-Like Structures Based on Circular Sensor Array and Lamb Waves
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Wang, Z., Yan, Y., Gao, Z., and Shi, B.
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- 2024
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16. A Systematic Observational Study on Galactic Interstellar Ratio 18O/17O. II. C18O and C17O J=2-1 Data Analysis
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Zou, Y. P., Zhang, J. S., Henkel, C., Romano, D., Liu, W., Zheng, Y. H., Yan, Y. T., Chen, J. L., Wang, Y. X., and Zhao, J. Y.
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Astrophysics - Astrophysics of Galaxies - Abstract
To investigate the relative amount of ejecta from high-mass versus intermediate-mass stars and to trace the chemical evolution of the Galaxy, we have performed with the IRAM 30m and the SMT 10m telescopes a systematic study of Galactic interstellar 18O/17O ratios toward a sample of 421 molecular clouds, covering a galactocentric distance range of 1-22 kpc. The results presented in this paper are based on the J=2-1 transition and encompass 364 sources showing both C18O and C17O detections. The previously suggested 18O/17O gradient is confirmed. For the 41 sources detected with both facilities, good agreement is obtained. A correlation of 18O/17O ratios with heliocentric distance is not found, indicating that beam dilution and linear beam sizes are not relevant. For the subsample of IRAM 30 m high-mass star-forming regions with accurate parallax distances, an unweighted fit gives 18O/17O = (0.12+-0.02)R_GC+(2.38+-0.13) with a correlation coefficient of R = 0.67. While the slope is consistent with our J=1-0 measurement, ratios are systematically lower. This should be caused by larger optical depths of C18O 2-1 lines, w.r.t the corresponding 1-0 transitions, which is supported by RADEX calculations and the fact that C18O/C17O is positively correlated with 13CO/C18O. After considering optical depth effects with C18O J=2-1 reaching typically an optical depth of 0.5, corrected 18O/17O ratios from the J=1-0 and J=2-1 lines become consistent. A good numerical fit to the data is provided by the MWG-12 model, including both rotating stars and novae., Comment: 17 pages, 11 figures, published in ApJS
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- 2023
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17. Sulfur isotope ratios in the Large Magellanic Cloud
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Gong, Y., Henkel, C., Menten, K. M., Chen, C. -H. R., Zhang, Z. Y., Yan, Y. T., Weiss, A., Langer, N., Wang, J. Z., Mao, R. Q., Tang, X. D., Yang, W., Ao, Y. P., and Wang, M.
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Astrophysics - Astrophysics of Galaxies - Abstract
Sulfur isotope ratios have emerged as a promising tool for tracing stellar nucleosynthesis, quantifying stellar populations, and investigating the chemical evolution of galaxies. While extensively studied in the Milky Way, in extragalactic environments they remain largely unexplored. We focus on investigating the sulfur isotope ratios in the Large Magellanic Cloud (LMC) to gain insights into sulfur enrichment in this nearby system and to establish benchmarks for such ratios in metal-poor galaxies. We conducted pointed observations of CS and its isotopologues toward N113, one of the most prominent star-formation regions in the LMC, utilizing the Atacama Pathfinder EXperiment 12~m telescope. We present the first robust detection of C$^{33}$S in the LMC by successfully identifying two C$^{33}$S transitions on a large scale of $\sim$5 pc. Our measurements result in an accurate determination of the $^{34}$S/$^{33}$S isotope ratio, which is 2.0$\pm$0.2. Our comparative analysis indicates that the $^{32}$S/$^{33}$S and $^{34}$S/$^{33}$S isotope ratios are about a factor of 2 lower in the LMC than in the Milky Way. Our findings suggest that the low $^{34}$S/$^{33}$S isotope ratio in the LMC can be attributed to a combination of the age effect, low metallicity, and star formation history., Comment: 6 pages, 1 figures, 2 tables, accepted for publication in A&A, adjusted to the final version
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- 2023
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18. Experimental Limits on Solar Reflected Dark Matter with a New Approach on Accelerated-Dark-Matter-Electron Analysis in Semiconductors
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Zhang, Z. Y., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, T., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jiang, L., Karmakar, S., Li, H. B., Li, H. Y., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Singh, M. K., Sun, T. X., Tang, C. J., Tian, Y., Wang, G. F., Wang, J. Z., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhao, J. Z., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
Recently a dark matter-electron (DM-electron) paradigm has drawn much attention. Models beyond the standard halo model describing DM accelerated by high energy celestial bodies are under intense examination as well. In this Letter, a velocity components analysis (VCA) method dedicated to swift analysis of accelerated DM-electron interactions via semiconductor detectors is proposed and the first HPGe detector-based accelerated DM-electron analysis is realized. Utilizing the method, the first germanium based constraint on sub-GeV solar reflected DM-electron interaction is presented with the 205.4 kg$\cdot$day dataset from the CDEX-10 experiment. In the heavy mediator scenario, our result excels in the mass range of 5$-$15 keV/$c^2$, achieving a 3 orders of magnitude improvement comparing with previous semiconductor experiments. In the light mediator scenario, the strongest laboratory constraint for DM lighter than 0.1 MeV/$c^2$ is presented. The result proves the feasibility and demonstrates the vast potential of the VCA technique in future accelerated DM-electron analyses with semiconductor detectors., Comment: 7 pages, 4 figures. Version updated to match PRL version
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- 2023
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19. Projected WIMP sensitivity of the CDEX-50 dark matter experiment
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Geng, X. P., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Gong, H., Guo, Q. J., Guo, T., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jiang, L., Karmakar, S., Li, H. B., Li, H. Y., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Singh, M. K., Sun, T. X., Tang, C. J., Tian, Y., Wang, G. F., Wang, J. Z., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, J. Z., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
CDEX-50 is a next-generation project of the China Dark Matter Experiment (CDEX) that aims to search for dark matter using a 50-kg germanium detector array. This paper comprises a thorough summary of the CDEX-50 dark matter experiment, including an investigation of potential background sources and the development of a background model. Based on the baseline model, the projected sensitivity of weakly interacting massive particle (WIMP) is also presented. The expected background level within the energy region of interest, set to 2--2.5 keVee, is $\sim$0.01 counts keVee$^{-1}$ kg$^{-1}$ day$^{-1}$. At 90\% confidence level, the expected sensitivity to spin-independent WIMP-nucleon couplings is estimated to reach a cross-section of 5.1 $\times$ 10$^{-45}$ cm$^{2}$ for a WIMP mass of 5 GeV/c$^{2}$ with an exposure objective of 150 kg$\cdot$year and an analysis threshold of 160 eVee. This science goal will correspond to the most sensitive results for WIMPs with a mass of 2.2--8 GeV/c$^{2}$., Comment: 12 pages, 11 figures. Version updated to match JCAP version
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- 2023
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20. Correction of a High-Order Numerical Method for Approximating Time-Fractional Wave Equation
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Ramezani, M., Mokhtari, R., and Yan, Y.
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- 2024
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21. Application of Carbon Nanomaterials to Enhancing Tumor Immunotherapy: Current Advances and Prospects
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Li Y, Xu Z, Qi Z, Huang X, Li M, Liu S, Yan Y, and Gao M
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carbon nanoparticles ,immune cell ,tumor immunotherapy ,drug delivery ,immunosensors ,Medicine (General) ,R5-920 - Abstract
Yun Li,1,2 Zhijie Xu,3 Zijuan Qi,4 Xiaofeng Huang,1,2 Mingyu Li,5 Sijin Liu,1,2 Yuanliang Yan,6 Ming Gao1,2 1State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, People’s Republic of China; 2University of Chinese Academy of Sciences, Beijing, People’s Republic of China; 3Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 4Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, People’s Republic of China; 5Mudanjiang Medical University, Mu Danjiang, Hei Longjiang, People’s Republic of China; 6Department of Pharmacy, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of ChinaCorrespondence: Yuanliang Yan, Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People’s Republic of China, Email yanyuanliang@csu.edu.cn Ming Gao, State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, People’s Republic of China, Email minggao@rcees.ac.cnAbstract: Recent advances in tumor immunotherapy have highlighted the pivotal role of carbon nanomaterials, such as carbon dots, graphene quantum dots, and carbon nanotubes. This review examines the unique benefits of these materials in cancer treatment, focusing on their mechanisms of action within immunotherapy. These include applications in immunoregulation, recognition, and enhancement. We explore how these nanomaterials when combined with specific biomolecules, can form immunosensors. These sensors are engineered for highly sensitive and specific detection of tumor markers, offering crucial support for early diagnosis and timely therapeutic interventions. This review also addresses significant challenges facing carbon nanomaterials in clinical settings, such as issues related to long-term biocompatibility and the hurdles of clinical translation. These challenges require extensive ongoing research and discussion. This review is of both theoretical and practical importance, aiming to promote using carbon nanomaterials in tumor immunotherapy, potentially transforming clinical outcomes and enhancing patient care.Keywords: carbon nanoparticles, immune cell, tumor immunotherapy, drug delivery, immunosensors
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- 2024
22. Inflammatory and Immune Mechanisms in COPD: Current Status and Therapeutic Prospects
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Qi Y, Yan Y, Tang D, Han J, Zhu X, Cui M, Wu H, Tao Y, and Fan F
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copd ,immune system ,inflammation ,immune regulation ,Pathology ,RB1-214 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Yanan Qi,1,2 Yuanyuan Yan,1,2 Dawei Tang,1,2 Jingjing Han,1,2 Xinyi Zhu,1,2 Mengting Cui,1,2 Hongyan Wu,3 Yu Tao,1,2 Fangtian Fan1,2 1School of Pharmacy, Bengbu Medical University, Bengbu, People’s Republic of China; 2Anhui Engineering Technology Research Center of Biochemical Pharmaceutical, Bengbu, People’s Republic of China; 3Institute of Biomedical Technology, Jiangsu Vocational College of Medicine, Yancheng, Jiangsu, 224005, People’s Republic of ChinaCorrespondence: Yu Tao; Fangtian Fan, Anhui Engineering Technology Research Center of Biochemical Pharmaceutical Bengbu Medical College, 2600 Donghai Avenue, Bengbu, Anhui, 233003, People’s Republic of China, Tel +86-15852921284 ; +86-16655258065, Email YuTao@bbmc.edu.cn; 2019050@bbmu.edu.cnBackground: Chronic obstructive pulmonary disease (COPD) currently ranks among the top three causes of mortality worldwide, presenting as a prevalent and complex respiratory ailment. Ongoing research has underscored the pivotal role of immune function in the onset and progression of COPD. The immune response in COPD patients exhibits abnormalities, characterized by diminished anti-infection capacity due to immune senescence, heightened activation of neutrophils and macrophages, T cell infiltration, and aberrant B cell activity, collectively contributing to airway inflammation and lung injury in COPD.Objective: This review aimed to explore the pivotal role of the immune system in COPD and its therapeutic potential.Methods: We conducted a review of immunity and COPD published within the past decade in the Web of Science and PubMed databases, sorting through and summarizing relevant literature.Results: This article examines the pivotal roles of the immune system in COPD. Understanding the specific functions and interactions of these immune cells could facilitate the development of novel therapeutic strategies and interventions aimed at controlling inflammation, enhancing immune function, and mitigating the impact of respiratory infections in COPD patients.Keywords: COPD, immune system, inflammation, immune regulation
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- 2024
23. Comparison of Nucleotide MALDI-TOF MS with Xpert MTB/RIF for Rifampicin Susceptibility Identification and Associated Risk Factors of Rifampicin Resistance Among Drug Resistant Mycobacterium tuberculosis
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Song S, Xu H, Cao J, Wu G, Sun H, Dai X, Li X, Chen M, Zhang M, Yan Y, Tong J, and Wang Z
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mtb ,rifampicin ,nucleotide maldi-tof ms ,xpert mtb/rif ,comparison ,risk factors ,Infectious and parasitic diseases ,RC109-216 - Abstract
Song Song,1,* Honghong Xu,1,* Jiawei Cao,2,* Guanghong Wu,2 Haiyan Sun,1 Xiaoqi Dai,1 Xuekui Li,1 Meng Chen,1 Menghan Zhang,1 Yueming Yan,1 Jingfeng Tong,3 Zhongdong Wang1 1Institute of Tuberculosis Control, Qingdao Preventive Medicine Research Institute, Qingdao Municipal Center for Disease Control and Prevention, Qingdao, People’s Republic of China; 2Department of Laboratory Medicine, Qingdao Chest Hospital, Qingdao, Shandong, People’s Republic of China; 3Department of Medical Affairs, Shanghai Conlight Medical Co., Ltd., Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhongdong Wang, Institute of Tuberculosis Control, Qingdao Preventive Medicine Research Institute, Qingdao Municipal Center for Disease Control and Prevention, No. 8, Fengxian Road, Jinhu Road Street, Shinan District, Qingdao City, Shandong Province, 266000, People’s Republic of China, Email jkzxtb1@163.comPurpose: Nucleotide-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry (nucleotide MALDI-TOF MS) is an emerging molecular technology used for the diagnosis of tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB)and its drug resistance. This study aimed to compare the ability of nucleotide MALDI-TOF MS to detect rifampicin (RIF) resistance in drug-resistant TB (DR-TB) patients with Xpert MTB/RIF and to analyze the disparate results individually. Additionally, potential factors associated with rifampicin resistance among DR-TB patients in Qingdao were investigated.Patients and Methods: A retrospective study was conducted at Qingdao Chest Hospital, and patients with DR-TB were enrolled. Corresponding frozen isolates were recovered and subjected to nucleotide MALDI-TOF MS, Xpert MTB/RIF, and phenotypic drug susceptibility testing (pDST). Sanger sequencing was performed for the discordant results of nucleotide MALDI-TOF MS and Xpert MTB/RIF. Univariate and multivariate logistic regression analyses were used to identify potential factors associated with rifampicin resistance among patients with DR-TB.Results: A total of 125 patients with DR-TB (18.8%, 125/668) were enrolled in this study from May 1 to July 31, 2023. Rifampicin-resistant (DR-TB/RR, 29) and rifampicin-sensitive (DR-TB/RS, 96) groups were divided according to the pDST results. Nucleotide MALDI-TOF MS performed better than Xpert MTB/RIF in terms of sensitivity, specificity, accuracy, and agreement with pDST. Only six cases had inconsistent results, and the sequencing results of five cases were identical to nucleotide MALDI-TOF MS. Furthermore, chest pain (aOR=12.84, 95% CI, 2.29– 91.97, p=0.005), isoniazid sensitivity (aOR=0.14, 0.02– 0.59, p=0.013), and ethambutol sensitivity (aOR=0.02, 0.00– 0.10, p=0.000) were potential factors associated with rifampicin resistance among DR-TB patients in Qingdao.Conclusion: The overall concordance between nucleotide MALDI-TOF MS and Xpert MTB/RIF was 95.2%, with the former performing better in determining rifampicin susceptibility among DR-TB cases in Qingdao. Chest pain, isoniazid, and ethambutol resistance might be factors associated with RIF resistance among patients with DR-TB in Qingdao.Keywords: MTB, rifampicin, nucleotide MALDI-TOF MS, Xpert MTB/RIF, comparison, risk factors
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- 2024
24. The Application of Nanotechnology for the Diagnosis and Treatment of Endocrine Disorders: A Review of Current Trends, Toxicology and Future Perspective
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Yan Y, Cai H, and Yang M
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nanomedicines ,theranostics ,endocrine disorders ,diabetes ,thyroid dysfunction ,Medicine (General) ,R5-920 - Abstract
Yan Yan, Hanqing Cai, Maoguang Yang Department of Endocrinology, The Second Hospital of Jilin University, Changchun, 13000, People’s Republic of ChinaCorrespondence: Maoguang Yang, Department of Endocrinology, The Second Hospital of Jilin University, Changchun, 13000, People’s Republic of China, Email yangmaoguang@jlu.edu.cnAbstract: The endocrine system regulates many biological systems, and disruptions may result in disorders, such as diabetes, thyroid dysfunction, Cushing’s syndrome, and obesity. The total incidence of endocrine illnesses was found to be 47.4%, excluding type 2 diabetes mellitus, with a significant frequency of newly diagnosed endocrine disorders. Nanotechnology manipulates particles at the atomic and molecular levels, opening up new paths for studying disease etiology and therapeutic alternatives. The goal of using nanomaterials in the treatment of endocrine illnesses is to create endogenous nano-biosensors that can detect even modest changes in hormone levels and react spontaneously to restore normal function. The size and surface characteristics of nanoparticles enhances the sensitivity in nano-sensors and are functionalized for targeted drug delivery. Nano-sized carriers composed of lipids, polymers, carbon, or metals have been shown to work much better than standard drug delivery methods. Nanoparticles (NPs) offer various advantages over current methods for diagnosing and treating endocrine disorders, acting as hydrogels for insulin delivery and wound healing. Incorporating selenium NPs into inorganic nanoparticles enhances their bioactivity and targeted delivery. Gold NPs show a promising precise insulin delivery. Mesoporous silica NPs maintain glycemic level effectively and lipid and polymeric NPs protect drugs from degradation in the gastrointestinal tract. Carbon nanotubes (CNTs) have become popular in thyroid surgeries. These characteristics make nanoparticles valuable for developing effective diagnostic and therapeutic systems. NP-based medicines have been thoroughly researched in order to identify the beginning point for the creation of theranostics, which may function in two ways: as imaging agents or therapeutics. The study posits that nanotechnology bridges diagnostics and therapies, potentially revolutionizing endocrine disorder treatments. This review delves into nanotechnology techniques, emphasizing their applications in diagnosing and treating diabetes mellitus.Keywords: nanomedicines, theranostics, endocrine disorders, diabetes, thyroid dysfunction
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- 2024
25. Coinhibitory Molecule VISTA Play an Important Negative Regulatory Role in the Immunopathology of Bronchial Asthma
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Yin J, Chen J, Wang T, Sun H, Yan Y, Zhu C, Huang L, and Chen Z
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vista ,bronchial asthma ,th2 cells ,cytokines ,anti-vista mab ,vista fusion protein ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Jianqun Yin,* Jiawei Chen,* Ting Wang, Huiming Sun, Yongdong Yan, Canhong Zhu, Li Huang, Zhengrong Chen Respiratory Department, Children’s Hospital of Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhengrong Chen; Li Huang, Respiratory Department, Children’s Hospital of Soochow University, No. 303 Jingde Road, Gusu District, Suzhou City, Jiangsu Province, People’s Republic of China, Tel +86-13771721180 ; +86-18962183510, Email chenzhengrong@suda.edu.cn; huanglilcy@163.comObjective: To investigate the significance of VISTA in bronchial asthma and its impact on the disease.Methods: Human peripheral blood of asthma children was gathered. The expression concentrations of VISTA, IL-4, IL-6, CD25, CD40L, and PD-L2 in peripheral blood plasma were detected by ELISA. We established the mouse model of asthma and intervened with agonistic anti-VISTA mAb (4C11) and VISTA fusion protein. ELISA, flow cytometry, and Western blotting were performed to detect the expression levels of Th1, Th2, and Th17 cell subsets and related characteristic cytokines, as well as the protein levels of MAPKs, NF-κB, and TRAF6 in lung tissues. In addition, the infiltration of eosinophils and inflammatory cells, airway mucus secretion, and VISTA protein expression in lung histopathological sections of different groups of mice were analyzed.Results: The concentration of VISTA in human asthma group decreased significantly (p < 0.05); A positive correlation was observed between VISTA and CD40L. The intervention of 4C11 mAb and fusion protein respectively during the induction period increase the differentiation of Th1 cells and the secretion of IFN-γ, and inhibit the differentiation of Th2 and Th17 cells, as well as the secretion of IL-4, IL-5, IL-13 and IL-17, partially reduce the pathological changes of asthma in mouse lungs and correct the progress of asthma. The MAPK, NF-κB, and TRAF6 protein levels were the middle range in the 4C11 mAb and fusion protein groups (p < 0.05).Conclusion: The findings suggest VISTA may play a negative regulatory role in the occurrence and development of bronchial asthma.Keywords: VISTA, bronchial asthma, Th2 cells, cytokines, anti-VISTA mAb, VISTA fusion protein
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- 2024
26. Effective Hamiltonian approach to the quantum phase transitions in the extended Jaynes-Cummings model
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Cui, H. T., Yan, Y. A., Qin, M., and Yi, X. X.
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Quantum Physics - Abstract
The study of phase transitions in dissipative quantum systems based on the Liouvillian is often hindered by the difficulty of constructing a time-local master equation when the system-environment coupling is strong. To address this issue, the complex discretization approximation for the environment is proposed to study the quantum phase transition in the extended Jaynes-Cumming model with an infinite number of boson modes. This approach yields a non-Hermitian effective Hamiltonian that can be used to simulate the dynamics of the spin. It is found that the ground state of this effective Hamiltonian determines the spin dynamics in the single-excitation subspace. Depending on the opening of the energy gap and the maximum population of excitations on the spin degree of freedom, three distinct phases can be identified: fast decaying, localized, and stretched dynamics of the spin. This approach can be extended to multiple excitations, and similar dynamics were found in the double-excitation subspace, indicating the robustness of the single-excitation phase., Comment: 12pages, published version
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- 2023
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27. FAST pulsar database: I. Polarization profiles of 682 pulsars
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Wang, P. F., Han, J. L., Xu, J., Wang, C., Yan, Y., Jing, W. C., Su, W. Q., Zhou, D. J., and Wang, T.
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Astrophysics - High Energy Astrophysical Phenomena ,High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
Pulsar polarization profiles are very basic database for understanding the emission processes in pulsar magnetosphere. After careful polarization calibration of the 19-beam L-band receiver and verification of beam-offset observation results, we obtain polarization profiles of 682 pulsars from observations by the Five-hundred-meter Aperture Spherical radio Telescope (FAST) during the survey tests for the Galactic Plan Pulsar Snapshot (GPPS) survey and other normal FAST projects. Among them, polarization profiles of about 460 pulsars are observed for the first time. The profiles exhibit diverse features. Some pulsars have a polarization position angle curve with a good S-shaped swing, and some with orthogonal modes; some have components with highly linearly components or strong circularly polarized components; some have a very wide profile, coming from an aligned rotator, and some have an interpulse from a perpendicular rotator; some wide profiles are caused by interstellar scattering. We derive geometry parameters for 190 pulsars from the S-shaped position angle curves or with orthogonal modes. We find that the linear and circular polarization or the widths of pulse profiles have various frequency dependencies. Pulsars with large fraction of linear polarization are more likely to have a large Edot., Comment: 38 pages, 23 figures. All the polarized pulse profiles presented in this paper are available on the webpage http://zmtt.bao.ac.cn/psr-fast/
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- 2023
28. Strong and weak pulsar radio emission due to thunderstorms and raindrops of particles in the magnetosphere
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Chen, X., Yan, Y., Han, J. L., Wang, C., Wang, P. F., Jing, W. C., Lee, K. J., Zhang, B., Xu, R. X., Wang, T., Yang, Z. L., Su, W. Q., Cai, N. N., Wang, W. Y., Qiao, G. J., Xu, J., and Zhou, D. J.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Pulsars radiate radio signals when they rotate. However, some old pulsars often stop radiating for some periods. The underlying mechanism remains unknown, while the magnetosphere during nulling phases is hard to probe due to the absence of emission measurement. Here we report the detection and accurate polarization measurements of sporadic weak narrow dwarf pulses detected in the ordinary nulling state of pulsar B2111+46 via the Five-Hundred-Meter Aperture Spherical radio Telescope (FAST). Further analysis shows that their polarization angles follow the average polarization angle curve of normal pulses, suggesting no change of magnetic field structure in the emission region in the two emission states. Whereas radio emission of normal individual pulses is radiated by a thunderstorm of particles produced by copious discharges in regularly formed gaps, dwarf pulses are produced by one or a few raindrops of particles generated by pair production in a fragile gap of this near-death pulsar., Comment: 37 pages, 15 figures. Authors version. Great FAST pulsar data. Share full-text access: https://rdcu.be/djLSL
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- 2023
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29. Local adaptive insulation in amorphous powder cores with low core loss and high DC bias via ultrasonic rheomolding
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Li, H. Z., Yan, Y. Q., Cai, W. S., Li, L. Y., Yan, A., Liu, L. H., Ma, J., Ke, H. B., Li, Q., Sun, B. A., Wang, W. H., and Yang, C.
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- 2024
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30. Study of Mechanical Properties and Failure Mechanism of CFRP-Aluminum Alloy Self-Piercing Riveted-Adhesive Joints
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Yan, Y. Q., Xu, S., Xing, Y. F., Bian, H. L., and Wu, H. F.
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- 2024
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31. Searching for $^{76}$Ge neutrinoless double beta decay with the CDEX-1B experiment
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Zhang, B. T., Wang, J. Z., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Karmakar, S., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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Nuclear Experiment ,High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
We operated a p-type point contact high purity germanium (PPCGe) detector (CDEX-1B, 1.008 kg) in the China Jinping Underground Laboratory (CJPL) for 500.3 days to search for neutrinoless double beta ($0\nu\beta\beta$) decay of $^{76}$Ge. A total of 504.3 kg$\cdot$day effective exposure data was accumulated. The anti-coincidence and the multi/single-site event (MSE/SSE) discrimination methods were used to suppress the background in the energy region of interest (ROI, 1989$-$2089 keV for this work) with a factor of 23. A background level of 0.33 counts/(keV$\cdot$kg$\cdot$yr) was realized. The lower limit on the half life of $^{76}$Ge $0\nu\beta\beta$ decay was constrained as $T_{1/2}^{0\nu}\ > \ {1.0}\times 10^{23}\ \rm yr\ (90\% \ C.L.)$, corresponding to the upper limits on the effective Majorana neutrino mass: $\langle m_{\beta\beta}\rangle < $3.2$-$7.5$\ \mathrm{eV}$., Comment: 11 pages, 12 figures, 2 tables. Version updated to match CPC version
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- 2023
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32. Effective Hamiltonian approach to the exact dynamics of open system by complex discretization approximation for environment
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Cui, H. T., Yan, Y. A., Qin, M., and Yi, X. X.
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Quantum Physics - Abstract
The discretization approximation method commonly used to simulate the open dynamics of system coupled to the environment in continuum often suffers from the recurrence. To address this issue, this paper proposes a noval generalization of the discretization approximation method in the complex plane using complex Gauss quadratures. The effective Hamiltonian can be constructed by this way, which is non-Hermitian and demonstrates the complex energy modes with negative imaginary part, describing accurately the dissipative dynamics of the system. This method is applied to examine the dynamics in two exactly solvable models: the dephasing model and the single-excitation open dynamics in the Aubry-Andr\'{e}-Harper model. This approach not only significantly reduces recurrence and improve the effectiveness of calculation, but also provide the microscopic viewpoint on the dynamics of system through the effective Hamiltonian. In addition, a simple relationship between the parameters in computation and the effectiveness of evaluation is also established., Comment: Title is changed. A significant improvement. The discussion about the open dynamics of AAH model is completely rewriteen
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- 2023
33. Main Airborne Pollen Species and Characteristics of Allergic Rhinitis Patients with Pollen-Related Allergies in 13 Northern Chinese Cities
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Zhang J, Yan Y, Jiang F, Chen J, Ouyang Y, and Zhang L
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allergic rhinitis ,pollen monitoring ,northern china ,questionnaire survey ,symptom scores ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Jingxuan Zhang,1,* Yun Yan,1,* Feifei Jiang,2,* Jingguo Chen,3,* Yuhui Ouyang,1,4,5 Luo Zhang1,4,5 1Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Otolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China; 3Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi ‘an Jiaotong University, Xi’an, People’s Republic of China; 4Beijing Laboratory of Allergic Diseases, Municipal Education Commission and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, People’s Republic of China; 5Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuhui Ouyang; Luo Zhang, Department of Allergy, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing, 100730, People’s Republic of China, Tel +8610 58268375 ; +8610 65141136, Fax +8610 85115988, Email oyyuhui@sina.com; dr.luozhang@139.comBackground: Pollen allergies have a high prevalence in northern China, whereas, the types of pollen allergens and population characteristics among different regions remain unclear.Objective: To study the species and temporal distribution of the main allergenic pollen, as well as the characteristics of patients with pollen-related allergic rhinitis (AR) in different cities in northern China.Methods: Pollen data were obtained from pollen-monitoring stations in 13 cities of northern China between 2020 and 2021. Questionnaire surveys and allergen testing were conducted in 494 patients with pollen-related allergies from Beijing in Central, Shenyang in Northeast, and Xi’an in Northwest China.Results: In 13 cities of northern China, the main sources of pollen were cypress, poplar, elm, pine, birch and ash in spring, and mugwort, goosefoot, hop and ragweed in autumn. In Northwest China, the spring and autumn pollen periods started earlier and lasted longer than that in Central and Northeast China, and the pollen counts in autumn in was significantly higher than that in Central and Northeast China. Furthermore, the nasal, ocular and respiratory symptom and quality of life scores of AR patients in Northwest China were significantly higher than that in Central and Northeast China. 69.32– 73.28% of patients had annual cost of anti-allergic medication between 500– 5000 yuan. However, 40.93– 48.86% of patients reported minor control of symptoms.Conclusion: Our results can be used as a basis for developing effective prevention and management measures for patients with pollen-related allergy in these regions, including timely pollen monitoring, patient guidance on protective measures, early intervention, and specific immunotherapy, to improve pollen-related allergy management.Keywords: allergic rhinitis, pollen monitoring, Northern China, questionnaire survey, symptom scores
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- 2024
34. Potential Role of Tranexamic Acid in Rosacea Treatment: conquering Flushing Beyond Melasma
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Zhang J, Gu D, Yan Y, Pan R, Zhong H, Zhang C, and Xu Y
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rosacea ,tranexamic acid ,topical ,oral ,microinjection ,Dermatology ,RL1-803 - Abstract
Jiawen Zhang,1,* Duoduo Gu,2,* Yang Yan,3,* Ruoxin Pan,2 Hui Zhong,4,5 Chengfeng Zhang,1 Yang Xu2 1Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, People’s Republic of China; 2Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 3Department of Cardiology, Ren Ji Hospital of Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 4State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, People’s Republic of China; 5School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chengfeng Zhang; Yang Xu, Email e3dangdang@hotmail.com; yangxu@njmu.edu.cnAbstract: Rosacea is a chronic inflammatory skin disease that affects a patient’s appearance and quality of life. It mainly affects the midface region and presents as erythema, flushing, telangiectasia, papules, pustules, and rhinophyma. Despite its prevalence, the precise pathophysiology of rosacea remains unknown, and novel pharmacological therapies are currently under investigation. Tranexamic acid (TA) is a synthetic, lysine-like compound that competitively inhibits fibrinogen production by synthesizing fibrinolytic enzymes. In addition to its popular application in hemorrhage treatment, TA has been used to manage a number of skin conditions, including melasma, chronic urticaria, and angioedema. TA is a better option for melasma treatment. However, the role of TA in treating rosacea has not yet been systematically elucidated. In this study, we reviewed all available literature on the use of TA for rosacea treatment. The included articles examined the therapeutic effects of TA in patients with rosacea, including traditional methods such as oral and topical administration and more novel approaches such as intradermal injections, microneedling, and laser-assisted delivery. Several recent clinical studies demonstrated that TA alleviates rosacea symptoms by restoring the permeability barrier, ameliorating the immune reaction, and inhibiting angiogenesis. In this review, we summarized the function and potential application of TA in rosacea treatment, aiming to facilitate the implementation of clinical applications.Keywords: rosacea, tranexamic acid, topical, oral, microinjection
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- 2024
35. Developing a Multi-Dimensional Health Index System for a General Occupational Population in the Light of Health Ecology Theory: A Delphi Study
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Zhou X, Wu J, Liu Y, Yan Y, Zhou G, and Li M
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health ecology ,delphi method ,multidimensional health ,index system ,Public aspects of medicine ,RA1-1270 - Abstract
Xiaoling Zhou,1,2 Jing Wu,3 Ying Liu,3 Yuzhong Yan,2 Geyao Zhou,1 Ming Li1,4 1School of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, People’s Republic of China; 2Research Department, Shanghai University of Medicine&Health Sciences Affiliated Zhoupu Hospital, Shanghai, People’s Republic of China; 3School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 4Party Committee office, Tongji University Affiliated Shanghai East Hospital, Shanghai, People’s Republic of ChinaCorrespondence: Ming Li; Geyao Zhou, Email liming1070202306@163.com; zhougeyao@163.comBackground: The health status of the occupational population is critical to the development of countries and regions as it is the main force of social and economic development. However, there is a dearth of comprehensive and systematic indicators to evaluate the health of occupational groups. This study aimed to construct a multi-dimensional evaluation index system for the general population.Methods: This study combined a literature review and initially established a multidimensional health system framework for the occupational population based on health ecology theory and then used two rounds of Delphi expert consultation to construct the final multidimensional health index system for the occupational population. Fifteen experts from related fields were selected for two rounds of Delphi expert consultation.Results: The recovery rates of the two rounds of expert questionnaires were 100.00% and 93.33% respectively, the expert authority coefficient were 0.90, and the Kendall’s coordination coefficients of the first and second level indexes were 0.32 and 0.42 (P ≥ 0. 001). The final index system includes four primary indicators (individual characteristics, health knowledge, health behavior, and health skills), 13 second-level indicators, and 41 third-level indicators; the weight coefficients of the four primary health dimensions are relatively close, and the “health knowledge” is slightly higher.Conclusion: The multi-dimensional health index system of the occupational population established in this study is comprehensive and reasonable from the perspective of health ecology, which can provide a solid foundation for the further development of a comprehensive health status prediction model for the occupational population.Keywords: health ecology, delphi method, multidimensional health, index system
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- 2024
36. A Possible Chemical Clock in High-mass Star-forming Regions: N(HC3N)/N(N2H+)?
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Wang, Y. X., Zhang, J. S., Yu, H. Z., Wang, Y., Yan, Y. T., Chen, J. L., Zhao, J. Y., and Zou, Y. P.
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Astrophysics - Astrophysics of Galaxies - Abstract
We conducted observations of multiple HC3N (J = 10-9, 12-11, and 16-15) lines and the N2H+ (J = 1-0) line toward a large sample of 61 ultracompact (UC) H II regions, through the Institutde Radioastronomie Millmetrique 30 m and the Arizona Radio Observatory 12 m telescopes. The N2H+ J = 1-0 line is detected in 60 sources and HC3N is detected in 59 sources, including 40 sources with three lines, 9 sources with two lines, and 10 sources with one line. Using the rotational diagram, the rotational temperature and column density of HC3N were estimated toward sources with at least two HC3N lines. For 10 sources with only one HC3N line, their parameters were estimated, taking one average value of Trot. For N2H+, we estimated the optical depth of the N2H+ J = 1-0 line, based on the line intensity ratio of its hyperfine structure lines. Then the excitation temperature and column density were calculated. When combining our results in UC H II regions and previous observation results on high-mass starless cores and high-mass protostellar cores, the N(HC3N)/N(N2H+) ratio clearly increases from the region stage. This means that the abundance ratio changes with the evolution of high-mass star-forming regions (HMSFRs). Moreover, positive correlations between the ratio and other evolutionary indicators (dust temperature, bolometric luminosity, and luminosity-to-mass ratio) are found. Thus we propose the ratio of N(HC3N)/N(N2H+) as a reliable chemical clock of HMSFRs., Comment: 40 pages, 8 figures and 8 tables
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- 2023
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37. Online Heatmap Generation with Both High and Low Weights
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Liu, Yan Y. and Allen-Dumas, Melissa
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Computer Science - Graphics - Abstract
Heatmap is a common geovisualization method that interpolates and visualizes a set of point observations on a map surface. Most of online web mapping libraries implement a one-pass heatmap algorithm using HTML5 canvas or WebGL for efficient heatmap generation. However, such implementation applies additive operations that accumulate the rendering of point weights on the map surface grid, making it inappropriate for visualizations that require the highlighting of both low and high weights. We introduce \textit{hilomap}, an online heatmap algorithm that highlights surface areas where points with both low and high trends are located. An HTML5 Canvas-based reference implementation on OpenLayers is presented and evaluated., Comment: The 4th ACM SIGSPATIAL International Workshop on Spatial Gems (SpatialGems 2022)
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- 2022
38. Direct measurements of carbon and sulfur isotope ratios in the Milky Way
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Yan, Y. T., Henkel, C., Kobayashi, C., Menten, K. M., Gong, Y., Zhang, J. S., Yu, H. Z., Yang, K., Xie, J. J., and Wang, Y. X.
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Astrophysics - Astrophysics of Galaxies - Abstract
With the IRAM 30 meter telescope, we performed observations of the $J$ = 2-1 transitions of CS, C$^{33}$S, C$^{34}$S, C$^{36}$S, $^{13}$CS, $^{13}$C$^{33}$S, and $^{13}$C$^{34}$S as well as the $J$ = 3-2 transitions of C$^{33}$S, C$^{34}$S, C$^{36}$S, and $^{13}$CS toward a large sample of 110 HMSFRs. We measured the $^{12}$C/$^{13}$C, $^{32}$S/$^{34}$S, $^{32}$S/$^{33}$S, $^{32}$S/$^{36}$S, $^{34}$S/$^{33}$S, $^{34}$S/$^{36}$S, and $^{33}$S/$^{36}$S abundance ratios with rare isotopologs of CS, thus avoiding significant saturation effects. With accurate distances obtained from parallax data, we confirm previously identified $^{12}$C/$^{13}$C and $^{32}$S/$^{34}$S gradients as a function of galactocentric distance (RGC). In the CMZ, $^{12}$C/$^{13}$C ratios are higher than suggested by a linear fit to the disk values as a function of RGC. While $^{32}$S/$^{34}$S ratios near the Galactic center and in the inner disk are similar, this is not the case for $^{12}$C/$^{13}$C, when comparing central values with those near RGC of 5 kpc. As was already known, there is no $^{34}$S/$^{33}$S gradient but the average ratio of 4.35~$\pm$~0.44 derived from the $J$ = 2-1 transition lines of C$^{34}$S and C$^{33}$S is well below previously reported values. A comparison between solar and local interstellar $^{32}$S/$^{34}$S and $^{34}$S/$^{33}$S ratios suggests that the Solar System may have been formed from gas with a particularly high $^{34}$S abundance. For the first time, we report positive gradients of $^{32}$S/$^{33}$S, $^{34}$S/$^{36}$S, $^{33}$S/$^{36}$S, and $^{32}{\rm S}/^{36}{\rm S}$ in our Galaxy. The predicted $^{12}$C/$^{13}$C ratios from the latest GCE models are in good agreement with our results. While $^{32}$S/$^{34}$S and $^{32}$S/$^{36}$S ratios show larger differences at larger RGC, $^{32}$S/$^{33}$S ratios show an offset across the entire inner 12 kpc of the Milky Way., Comment: HMSFRs: high-mass star-forming regions. CMZ: central molecular zone. GCE: Galactic chemical evolution. 68 pages, 12 tables, 18 figures. Accepted for publication in A&A
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- 2022
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39. Search for boosted keV-MeV light dark matter particles from evaporating primordial black holes at the CDEX-10 experiment
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Zhang, Z. H., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Karmakar, S., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
We present novel constraints on boosted light dark matter particles (denoted as ``$\chi$'') from evaporating primordial black holes (PBHs) using 205.4 kg$\cdot$day data from the China Jinping Underground Laboratory's CDEX-10 p-type point contact germanium detector with a 160 eVee analysis threshold. $\chi$ from PBHs with masses ranging from 1$\times$10$^{15}$ g to 7$\times$10$^{16}$ g are searched in this work. In the presence of PBH abundance compatible with present bounds, our result excludes the $\chi$-nucleon elastic-scattering cross section region from 3.4$\times$10$^{-32}$ cm$^{2}$ to 2.3$\times$10$^{-29}$ cm$^{2}$ for $\chi$ of 1 keV to 24 MeV from PBHs with masses of 5$\times$10$^{15}$ g, as well as from 1.1$\times$10$^{-28}$ cm$^{2}$ to 7.6$\times$10$^{-28}$ cm$^{2}$ for $\chi$ of 1 keV to 0.6 MeV from PBHs with masses of 7$\times$10$^{16}$ g. If the $\chi$-nucleon elastic-scattering cross section can be determined in the future, the abundance of PBHs may be severely constrained by $\chi$ evaporation. With the lower threshold (160 eVee) of the CDEX-10 experiment compared to the previously used experiments, this work allows for a better reach at soft spectra produced by heavier PBHs, which demonstrates the vast potential of such a technical route to pursue $\chi$ from larger PBHs with a low threshold., Comment: 8 pages, 6 figures. Version updated to match PRD version
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- 2022
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40. Search for exotic interactions of solar neutrinos in the CDEX-10 experiment
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Geng, X. P., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Karmakar, S., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, J. X., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y. F., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
We investigate exotic neutrino interactions using the 205.4 kg$\cdot$day dataset from the CDEX-10 experiment at the China Jinping Underground Laboratory. New constraints on the mass and couplings of new gauge bosons are presented. Two nonstandard neutrino interactions are considered: a $U(1)_{B-L}$ gauge-boson-induced interaction between an active neutrino and electron/nucleus, and a dark-photon-induced interaction between a sterile neutrino and electron/nucleus via kinetic mixing with a photon. This work probes an unexplored parameter space involving sterile neutrino coupling with a dark photon. New laboratory limits are derived on dark photon masses below $1~{\rm eV}/c^{2}$ at some benchmark values of $\Delta m_{41}^{2}$ and $g^{\prime2}{\rm{sin}}^{2}2\theta_{14}$., Comment: 6 pages, 4 figures. Version updated to match PRD version
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- 2022
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41. Discovery of non-metastable ammonia masers in Sagittarius B2
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Yan, Y. T., Henkel, C., Menten, K. M., Gong, Y., Nguyen, H., Ott, J., Ginsburg, A., Wilson, T. L., Brunthaler, A., Belloche, A., Zhang, J. S., Budaiev, N., and Jeff, D.
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Astrophysics - Astrophysics of Galaxies - Abstract
We report the discovery of widespread maser emission in non-metastable inversion transitions of NH$_3$ toward various parts of the Sagittarius B2 molecular cloud/star forming region complex: We detect masers in the $J,K = $ (6,3), (7,4), (8,5), (9,6), and (10,7) transitions toward Sgr B2(M) and Sgr B2(N), an NH$_3$ (6,3) maser in Sgr B2(NS), and NH$_3$ (7,4), (9,6), and (10,7) masers in Sgr B2(S). With the high angular resolution data of the Karl G. Jansky Very Large Array (JVLA) in A-configuration we identify 18 maser spots. Nine maser spots arise from Sgr B2(N), one from Sgr B2(NS), five from Sgr B2(M), and three in Sgr B2(S). Compared to our Effelsberg single dish data, the JVLA data indicate no missing flux. The detected maser spots are not resolved by our JVLA observations. Lower limits to the brightness temperature are $>$3000~K and reach up to several 10$^5$~K, manifesting the lines' maser nature. In view of the masers' velocity differences with respect to adjacent hot molecular cores and/or UCH{\scriptsize II} regions, it is argued that all the measured ammonia maser lines may be associated with shocks caused either by outflows or by the expansion of UCH{\scriptsize II} regions. Overall, Sgr B2 is unique in that it allows us to measure many NH$_3$ masers simultaneously, which may be essential to elucidate their so far poorly understood origin and excitation., Comment: 17 pages, 14 figures, 7 tables. Accepted for publication in A&A Letter
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- 2022
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42. Exotic Dark Matter Search with CDEX-10 Experiment at China's Jinping Underground Laboratory
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Dai, W. H., Jia, L. P., Ma, H., Yue, Q., Kang, K. J., Li, Y. J., An, H. P., C., Greeshma, Chang, J. P., Chen, Y. H., Cheng, J. P., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Karmakar, S., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yang, L. T., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
A search for exotic dark matter (DM) in the sub-GeV mass range has been conducted using 205 kg$\cdot$day data taken from a p-type point contact germanium detector of CDEX-10 experiment at China Jinping underground laboratory. New low-mass dark matter searching channels, neutral current fermionic DM absorption ($\chi+A\rightarrow \nu+A$) and DM-nucleus 3$\rightarrow$2 scattering ($\chi+\chi+A\rightarrow \phi+A$), have been analyzed with an energy threshold of 160 eVee. No significant signal was found. Thus new limits on the DM-nucleon interaction cross section are set for both models at sub-GeV DM mass region. A cross section limit for the fermionic DM absorption is set to be $\rm 2.5\times 10^{-46} cm^2$(90\% C.L.) at DM mass of 10 MeV/c$^2$. For the DM-nucleus 3$\rightarrow$2 scattering scenario, limits are extended to DM mass of 5 MeV/c$^2$ and 14 MeV/c$^2$ for the massless dark photon and bound DM final state, respectively., Comment: 5 pages, 7 figures
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- 2022
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43. Axial transition form factors of octet baryons in the perturbative chiral quark model
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Liu, X. Y., Limphirat, A., Xu, K., Zhao, Z., Khosonthongkee, K., and Yan, Y.
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High Energy Physics - Phenomenology - Abstract
We study the axial transition form factors $G_A^{B\to B'}(Q^2)$ as well as the axial charges $g_A^{B\to B'}$ of the octet baryons in the perturbative chiral quark model~(PCQM) with including both the ground and excited states in the intermediate quark propagators. The PCQM results on the $G_A^{B\to B'}(Q^2)$ and the $g_A^{B\to B'}$ are found in good agreement with the existing experimental data and the lattice-QCD values. The study figures out that the $G_A^{B\to B'}(Q^2)$ for all transitions behave in the dipolelike form, which is dominantly caused by the three-quark core. The meson cloud with the ground-state quark propagator also plays an extremely important role but results in a flat contribution. The excited-state quark propagator contributing to the $G_A^{B\to B'}(Q^2)$ could be regarded as the higher order correction and it is very limited.
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- 2022
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44. Chinese Healthcare Workers’ Knowledge, Attitudes, and Practices in Diabetic Kidney Management: A Multi-Centered Cross-Sectional Study
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Duan DF, Wen Y, Yan Y, Li L, Xiao X, Li X, Yan LJ, and Ma DY
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knowledge ,attitude ,practice ,diabetic kidney disease ,Public aspects of medicine ,RA1-1270 - Abstract
Di-fei Duan,1,* Yue Wen,1,* Yu Yan,1 Ling Li,2 Xiang Xiao,3 Xing Li,1 Lin-Jia Yan,4 Deng-Yan Ma1 1Department of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University /West China School of Nursing, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China; 2Department of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan Province, People’s Republic of China; 3West China School of Medicine, Sichuan University, Chengdu, Sichuan Province, People’s Republic of China; 4The Nethersole School of Nursing Faculty of Medicine, The Chinese University of Hong Kong, Hongkong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Deng-Yan Ma, Department of Nephrology, West China Hospital of Sichuan University, No. 37 Guoxuexiang, Wuhou District, Chengdu, Sichuan, People’s Republic of China, Email mdy5104@wchscu.cnBackground: Given the importance of diabetic kidney disease (DKD) management, this study aims to explore the knowledge, attitudes, and practices in disease management demonstrated by healthcare workers from the nephrology department.Materials and Methods: This study is a multi-centered cross-sectional study, and adopts snowball sampling, with 530 healthcare workers being recruited to complete a questionnaire covering areas such as demographic characteristics, knowledge, attitude, and practices (KAP) of DKD management. This data was analyzed using descriptive statistics and binary logistics analysis.Results: In this study, 530 healthcare workers were studied, including 94 doctors and 436 nurses. The participants were mainly from general tertiary hospitals in 14 provinces. For Chinese nurse, the results indicate that both poor knowledge level (Odds Ratio (OR) =0.63, 95% Confidence Interval (CI): 0.42– 0.94) and having experience in further medical training in nephrology (OR=1.92, 95% CI: 1.20– 3.08) are associated with the practice levels. For Chinese doctors, having not experience in further medical training in nephrology (OR=0.36, 95% CI: 0.15– 0.83) are associated with their practice levels.Conclusion: In summary, Chinese doctors and nurses in this study showed positive attitudes towards DKD management, but their knowledge and practical skills were lacking. This underscores a notable gap in achieving optimal DKD care. Notably, nurses’ knowledge influenced their management practices, and additional nephrology training correlated with better engagement. To improve patient care, enhancing nephrology healthcare professional training and addressing knowledge-practice disparities are recommended.Keywords: knowledge, attitude, practice, diabetic kidney disease
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- 2024
45. Clinical Features and Outcomes of Twin Pregnancies with Antiphospholipid Antibodies Positivity: A Retrospective Study
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Huang P, Wu R, Guo X, Gao X, Yan Y, Han C, and Xue F
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twin pregnancy ,antiphospholipid antibody ,pregnancy outcomes ,propensity score matching ,Public aspects of medicine ,RA1-1270 - Abstract
Pengzhu Huang,1,2,* Rongrong Wu,1,2,* Xin Guo,1,2,* Xiaoli Gao,1,2 Ye Yan,1,2 Cha Han,1,2 Fengxia Xue1,2 1Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China; 2Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fengxia Xue; Cha Han, Department of Gynecology and Obstetrics, Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China, Tel +86-22-60363769, Fax +86-22-27813550, Email xuefengxia@tmu.edu.cn; tjhancha@tmu.edu.cnObjective: This study aimed to evaluate the impact of twin pregnancies with antiphospholipid antibody (aPL) positivity, a rare and complex clinical condition that remains a huge challenge for management.Methods: This study enrolled twin-pregnant women at our hospital between January 2018 and August 2023. Women with and without aPL positivity were selected using propensity score matching (PSM). Clinical features and pregnancy outcomes were compared between the two groups in the PSM cohort. To analyze the effect of aPL positivity on pregnancy outcomes, multivariate logistic models were used to obtain adjusted odds ratios (aOR) with 95% confidence intervals (CI).Results: Among the 773 women with twin pregnancies, aPL positivity was found in 26 women (3.36%). In the PSM cohort, there were 24 twin-pregnant women with positive aPL, and 48 women without aPL were selected as controls. Twin-pregnant women with aPL positivity had a higher proportion of abortion (8.33% vs 0, P = 0.043), preterm birth < 34 weeks (33.33% vs 8.33%, P = 0.007) and very low birthweight (< 1500 g) (20.83% vs 4.17%, P = 0.016) than the control group. In addition, stillbirth of one fetus was observed in one twin-pregnant woman with positive aPL. Multivariate logistic regression analysis revealed that twin pregnancy with aPL positivity was associated with preterm birth < 34 weeks (aOR = 2.76, 95% CI: 0.83– 4.70, P = 0.005), very low birthweight (< 1500 g) (OR = 2.40, 95% CI: 0.18– 4.67, P = 0.034) and small for gestational age (SGA) (aOR = 1.66, 95% CI: 0.22– 3.10, P =0.024).Conclusion: Twin pregnancies with aPL positivity were correlated with obstetric complications, including abortion, preterm birth < 34 weeks and very low birthweight (< 1500 g). The detection of aPL may be of clinical significance for women with twin pregnancies and should be considered in future studies.Keywords: twin pregnancy, antiphospholipid antibody, pregnancy outcomes, propensity score matching
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- 2024
46. Interstellar Nitrogen Isotope Ratios: New NH3 Data from the Galactic Center out to the Perseus Arm
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Chen, J. L., Zhang, J. S., Henkel, C., Yan, Y. T., Yu, H. Z., Qiu, J. J., Tang, X. D., Wang, J., Liu, W., Wang, Y. X., Zheng, Y. H., Zhao, J. Y., and Zou, Y. P.
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Astrophysics - Astrophysics of Galaxies - Abstract
Our aim is to measure the interstellar 14N/15N ratio across the Galaxy, to establish a standard data set on interstellar ammonia isotope ratios, and to provide new constraints on the Galactic chemical evolution. The (J, K ) = (1, 1), (2, 2), and (3, 3) lines of 14NH3 and 15NH3 were observed with the Shanghai Tianma 65 m radio telescope (TMRT) and the Effelsberg 100 m telescope toward a large sample of 210 sources. One hundred fourty-one of these sources were detected by the TMRT in 14NH3. Eight of them were also detected in 15NH3. For 10 of the 36 sources with strong NH3 emission, the Effelsberg 100 m telescope successfully detected their 15NH3(1, 1) lines, including 3 sources (G081.7522, W51D, and Orion-KL) with detections by the TMRT telescope. Thus, a total of 15 sources are detected in both the 14NH3 and 15NH3 lines. Line and physical parameters for these 15 sources are derived, including optical depths, rotation and kinetic temperatures, and total column densities. 14N/15N isotope ratios were determined from the 14NH3/15NH3 abundance ratios. The isotope ratios obtained from both telescopes agree for a given source within the uncertainties, and no dependence on heliocentric distance and kinetic temperature is seen. 14N/15N ratios tend to increase with galactocentric distance, confirming a radial nitrogen isotope gradient. This is consistent with results from recent Galactic chemical model calculations, including the impact of superasymptotic giant branch stars and novae.
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- 2022
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47. Constraints on Sub-GeV Dark Matter--Electron Scattering from the CDEX-10 Experiment
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Zhang, Z. Y., Yang, L. T., Yue, Q., Kang, K. J., Li, Y. J., Agartioglu, M., An, H. P., Chang, J. P., Chen, Y. H., Cheng, J. P., Dai, W. H., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Ma, H., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Saraswat, K., Sharma, V., She, Z., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yeh, C. H., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
We present improved germanium-based constraints on sub-GeV dark matter via dark matter--electron ($\chi$-$e$) scattering using the 205.4 kg$\cdot$day dataset from the CDEX-10 experiment. Using a novel calculation technique, we attain predicted $\chi$-$e$ scattering spectra observable in high-purity germanium detectors. In the heavy mediator scenario, our results achieve 3 orders of magnitude of improvement for $m_{\chi}$ larger than 80 MeV/c$^2$ compared to previous germanium-based $\chi$-$e$ results. We also present the most stringent $\chi$-$e$ cross-section limit to date among experiments using solid-state detectors for $m_{\chi}$ larger than 90 MeV/c$^2$ with heavy mediators and $m_{\chi}$ larger than 100 MeV/c$^2$ with electric dipole coupling. The result proves the feasibility and demonstrates the vast potential of a new $\chi$-$e$ detection method with high-purity germanium detectors in ultralow radioactive background., Comment: 6 pages, 3 figures. Version updated to match PRL version
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- 2022
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48. Epigenetic Modifications of Histone in Lung Fibrosis
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Sanders, Yan Y., primary
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- 2024
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49. Enhanced Thermoelectric Performance of MnTe by Decoupling of Electrical and Thermal Transports
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Abdul Basit, Jiwu Xin, Yubo Luo, Ji‐Yan Y. Dai, and Junyou Yang
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carrier concentration ,GeTe ,microstructure ,MnTe ,thermoelectric ,Electric apparatus and materials. Electric circuits. Electric networks ,TK452-454.4 ,Physics ,QC1-999 - Abstract
Abstract Lead‐free polycrystalline manganese telluride holds great potential in the development of waste heat recovery due to its fascinating physical properties. However, the poor thermoelectric (TE) performance in the p‐type MnTe alloys always results from their inferior carrier concentration, leading to low power factor and high thermal conductivity which restrict the overall thermoelectric performance. In this work, the problem is solved by decoupling its electrical and thermal transports through the hole donor Ge‐deficiency in MnTe + x mol.% GeTe (0 ≤ x ≤ 4) compounds. Intrinsically, extra GeTe in MnTe + x mol.% GeTe compound offers free charge carriers due to a narrow bandgap comparatively, realizing not only a full assessment of stimulated electrical performance but also an enhanced power factor. Moreover, benefiting from the nano‐precipitates and tweed microstructures, the lattice thermal conductivity effectively reduces due to the intensive phonon scattering accordingly. Ultimately, a maximum ZT of ≈1.2 at 873 K in the 3 mol.% GeTe doped MnTe sample is realized.
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- 2024
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50. Search for Neutrinoless Double-Beta Decay of $^{76}$Ge with a Natural Broad Energy Germanium Detector
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CDEX collaboration, Dai, W. H., Ma, H., Yue, Q., She, Z., Kang, K. J., Li, Y. J., Agartioglu, M., An, H. P., Chang, J. P., Chen, Y. H., Cheng, J. P., Deng, Z., Fang, C. H., Geng, X. P., Gong, H., Guo, Q. J., Guo, X. Y., He, L., He, S. M., Hu, J. W., Huang, H. X., Huang, T. C., Jia, H. T., Jiang, X., Li, H. B., Li, J. M., Li, J., Li, Q. Y., Li, R. M. J., Li, X. Q., Li, Y. L., Liang, Y. F., Liao, B., Lin, F. K., Lin, S. T., Liu, S. K., Liu, Y. D., Liu, Y., Liu, Y. Y., Liu, Z. Z., Mao, Y. C., Nie, Q. Y., Ning, J. H., Pan, H., Qi, N. C., Ren, J., Ruan, X. C., Saraswat, K., Sharma, V., Singh, M. K., Sun, T. X., Tang, C. J., Tang, W. Y., Tian, Y., Wang, G. F., Wang, L., Wang, Q., Wang, Y., Wang, Y. X., Wong, H. T., Wu, S. Y., Wu, Y. C., Xing, H. Y., Xu, R., Xu, Y., Xue, T., Yan, Y. L., Yang, L. T., Yeh, C. H., Yi, N., Yu, C. X., Yu, H. J., Yue, J. F., Zeng, M., Zeng, Z., Zhang, B. T., Zhang, F. S., Zhang, L., Zhang, Z. H., Zhang, Z. Y., Zhao, K. K., Zhao, M. G., Zhou, J. F., Zhou, Z. Y., and Zhu, J. J.
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Nuclear Experiment ,High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
A natural broad energy germanium (BEGe) detector is operated in the China Jinping Underground Laboratory (CJPL) for a feasibility study of building the next generation experiment of the neutrinoless double-beta (0{$\nu\beta\beta$}) decay of $^{76}$Ge. The setup of the prototype facility, characteristics of the BEGe detector, background reduction methods, and data analysis are described in this paper. A background index of 6.4$\times$10$^{-3}$ counts/(keV$\cdot$kg$\cdot$day) is achieved and 1.86 times lower than our previous result of the CDEX-1 detector. No signal is observed with an exposure of 186.4 kg$\cdot$day, thus a limit on the half life of $^{76}$Ge 0$\nu\beta\beta$ decay is set at T$_{1/2}^{0\nu}$ $>$ 5.62$\times$10$^{22}$ yr at 90% C.L.. The limit corresponds to an effective Majorana neutrino mass in the range of 4.6 $\sim$ 10.3 eV, dependent on the nuclear matrix elements., Comment: 10 pages, 15 figures
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- 2022
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