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364 results on '"Yamazaki, Yukiko"'

5. Respiratory system compliance during anesthesia induction and postoperative mechanical ventilation needs: An observational study.

Author

Yamazaki, Yukiko, Matsuki, Yuka, Hosokawa, Koji, Tanaka, Katsuya, Kawamura, Yuko, Tanaka, Aiko, and Shigemi, Kenji

Subjects
RESPIRATORY organs, ARTIFICIAL respiration, LENGTH of stay in hospitals, SCIENTIFIC observation, ANESTHESIA, HOSPITAL mortality
Abstract

Background and Aims: Respiratory system compliance (Crs) is a simple indicator of lung flexibility. However, it remains unclear whether a low Crs during anesthesia induction (iCrs) is associated with an increased risk of postoperative mechanical ventilation. Methods: This retrospective observational study was conducted using a local database. All mechanically ventilated postoperative ICU patients were included in this study. The duration of postoperative mechanical ventilation, length of hospital stay, and in‐hospital mortality were compared between the low iCrs group (<25% of distribution) and the normal iCrs group. Results: A total of 315 patients were classified into the low iCrs (<39 mL/cmH2O) group (n = 78) or the normal iCrs group (n = 237). Low iCrs was associated with a higher chance of mechanical ventilation in 28 days (log‐rank test, p < 0.001). The duration of hospital stay was similar. Multivariate analysis showed that in‐hospital mortality was higher in the low iCrs group than in the normal iCrs group (adjusted odds ratio, 6.04 [1.13, 32.26]; p = 0.04). Conclusion: Low iCrs was associated with an increased risk of requiring postoperative mechanical ventilation. An additional result of poor survival related to low iCrs may require further study. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Comparison of Left Ventricular End-Diastolic Volume Approximated from Mean Blood Pressure and Stroke Volume and End-Diastolic Volume Calculated from Left Ventricular-Aortic Coupling.

Author

Shiraishi, Takahiro, Matsuki, Yuka, Yamazaki, Yukiko, and Shigemi, Kenji

Subjects
BLOOD pressure, SYSTOLIC blood pressure, SCATTER diagrams
Abstract

Objectives: The purpose of this study was to compare left ventricular end-diastolic volume (EDV), derived from left ventricular arterial coupling (Ees/Ea), and mean arterial blood pressure. Both of these methods of measuring EDV require some invasive procedure. However, the method of measuring EDV approximate is less invasive than the EDV coupling measuring method. This is because EDV approximate only requires arterial pressure waveform as an invasive procedure. Methods: This study included 14 patients with normal cardiac function who underwent general anesthesia. The point when blood pressure stabilized after the induction of anesthesia was taken as a baseline according to the study protocol. At the point when systolic arterial blood pressure fell 10% or more from the baseline blood pressure, 300 mL of colloid solution was administered over 15 min. EDV approximate and EDV coupling were calculated for each of the 14 patients at three points during the course of anesthetic. Each value was obtained by calculating a 5 min average. The timing of these three points was 5 min before, 5 min during, and 5 min after infusion loading. Results: The total number of comparable points was 42; 3 points were taken from each of the 14 participants. Both EDV approximate and EDV coupling increased through the infusion load testing. Scatter plots were prepared, and regression lines were calculated from the obtained values. A high correlation was shown between EDV approximate and EDV coupling (R2 = 0.96, p < 0.05). Conclusions: In patients with good cardiac function, EDV approximate can be substituted for EDV coupling, suggesting the possibility that EDV can be continuously and less invasively calculated under the situation of general anesthesia. [ABSTRACT FROM AUTHOR]

Published
2024
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32. The Plant Ontology as a Tool for Comparative Plant Anatomy and Genomic Analyses

Author

Cooper, Laurel, Walls, Ramona L., Elser, Justin, Gandolfo, Maria A., Stevenson, Dennis W., Smith, Barry, Preece, Justin, Athreya, Balaji, Mungall, Christopher J., Rensing, Stefan, Hiss, Manuel, Lang, Daniel, Reski, Ralf, Berardini, Tanya Z., Li, Donghui, Huala, Eva, Schaeffer, Mary, Menda, Naama, Arnaud, Elizabeth, Shrestha, Rosemary, Yamazaki, Yukiko, and Jaiswal, Pankaj

Published
2013
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43. NBRP databases: databases of biological resources in Japan

Author

Yamazaki, Yukiko, Akashi, Ryo, Banno, Yutaka, Endo, Takashi, Ezura, Hiroshi, Fukami-Kobayashi, Kaoru, Inaba, Kazuo, Isa, Tadashi, Kamei, Katsuhiko, Kasai, Fumie, Kobayashi, Masatomo, Kurata, Nori, Kusaba, Makoto, Matuzawa, Tetsuro, Mitani, Shohei, Nakamura, Taro, Nakamura, Yukio, Nakatsuji, Norio, Naruse, Kiyoshi, Niki, Hironori, Nitasaka, Eiji, Obata, Yuichi, Okamoto, Hitoshi, Okuma, Moriya, Sato, Kazuhiro, Serikawa, Tadao, Shiroishi, Toshihiko, Sugawara, Hideaki, Urushibara, Hideko, Yamamoto, Masatoshi, Yaoita, Yoshio, Yoshiki, Atsushi, and Kohara, Yuji

Published
2010
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46. Deletion of Orc4during oogenesis severely reduces polar body extrusion and blocks zygotic DNA replication†

Author

Nguyen, Hieu, Wu, Hongwen, Ung, Anna, Yamazaki, Yukiko, Fogelgren, Ben, and Ward, W Steven

Abstract

Origin recognition complex subunit 4 (ORC4) is a DNA-binding protein required for DNA replication. During oocyte maturation, after the last oocyte DNA replication step and before zygotic DNA replication, the oocyte undergoes two meiotic cell divisions in which half the DNA is ejected in much smaller polar bodies. We previously demonstrated that ORC4 forms a cytoplasmic cage around the DNA that is ejected in both polar body extrusion (PBE) events. Here, we used ZP3 activated Cre to delete exon 7 of Orc4during oogenesis to test how it affected both predicted functions of ORC4: its recently discovered role in PBE and its well-known role in DNA synthesis. Orc4deletion severely reduced PBE. Almost half of Orc4-depleted germinal vesicle (GV) oocytes cultured in vitro were arrested before anaphase I (48%), and only 25% produced normal first polar bodies. This supports the role of ORC4 in PBE and suggests that transcription of the full-length Orc4during oogenesis is required for efficient PBE. Orc4deletion also abolished zygotic DNA synthesis. Fewer Orc4-depleted oocytes developed to the metaphase II (MII) stage, and after activation these oocytes were arrested at the two-cell stage without undergoing DNA synthesis. This confirms that transcription of full-length Orc4after the primary follicle stage is required for zygotic DNA replication. The data also suggest that MII oocytes do not have a replication licensing checkpoint as cytokinesis progressed without DNA synthesis. Together, the data confirm that oocyte ORC4 is important for both PBE and zygotic DNA synthesis.ORC4 functions in polar body extrusion during oocyte maturation and fertilization, then in DNA replication in the zygote. Conditional knock-out of Orc4in primary follicles causes a reduction in PBE and complete inhibition of DNA synthesis in the zygote.Graphical Abstract

Published
2022
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