13 results on '"Yalcinkaya, FR"'
Search Results
2. Anti-inflammatory and antioxidant activity of thymoquinone in a rat model of acute bacterial prostatitis.
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Inci, M, Davarci, M, Motor, S, Yalcinkaya, FR, Nacar, E, Aydin, M, Sefil, NK, and Zararsız, I
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ANTI-inflammatory agents ,ANTIOXIDANTS ,LABORATORY rats ,PROSTATITIS ,ESCHERICHIA coli - Abstract
Prostatitis plays a major role in morbidity and mortality related to prostate diseases. The aim of this study was to detect whether thymoquinone (TQ) could ameliorate oxidative damage and the proliferative response induced by Escherichia coli (E. coli) in rats. A total of 42 adult male Wistar rats were used. The rats were randomly divided into seven groups (three treatment groups, three infected groups and one control group). Control group received saline and was killed 24 h after saline administration. Infected rats were killed after 24, 48 and 72 h following direct injection of E. coli into the prostate. Treatment groups were administered with 10 mg/kg dose of TQ intraperitoneally following E. coli injection and after 24 and 48 h following E. coli injection. The rats were killed at 24, 48 and 72 h after the first drug administration. Each group was compared with each other and with the control group. In addition, infected groups were compared with treatment groups. Our findings show that the treatment with TQ has a protective effect against bacterial prostatitis-induced tissue injury. Increase in malondialdehyde levels and histological damage caused by E. coli were improved markedly with TQ treatment. TQ treatment particularly increased the activity of glutathione peroxidase and decreased the activities of catalase and superoxide dismutase. These observations might be attributed, at least in part, to the antioxidant effect of TQ and suggest that it could be a clinically valuable agent in the prevention of acute prostatitis caused by E. coli. [ABSTRACT FROM PUBLISHER]
- Published
- 2013
- Full Text
- View/download PDF
3. Intraurethral Utterbasti Application for Urethral Injury in Rats
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Ali Ayyildiz, Mustafa Kerem, Mursel Davarci, Ahmet Gökçe, Rajendra Haribhau Am, Ayper Kacar, Mehmet Fatih Inci, Fatih Rüştü Yalçinkaya, Eşref Oğuz Güven, Rajendra Haribhau Amilkanthwar, Yalcinkaya, FR, Davarci, M, Gokce, A, Guven, EO, Inci, M, Kerem, M, Ayyildiz, A, Amilkanthwar, RH, Kacar, A, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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Urethral injury ,medicine.medical_specialty ,General Veterinary ,business.industry ,Urology ,Medicine ,Veterinary Sciences ,business ,Agronomy and Crop Science - Abstract
Urethral stricture is an illness that can be repeated and that has a troublous treatment process. Uttarbasti which is used in traditional Indian wound healing is a mixture consisting of rock salt, honey and sesame oil. In traditional treatment, there are studies about the effects of honey, wax and sesame oil on wound healing. Researchers aimed at searching the efficiency of the treatment by using uttarbasti in urethral stenosis. In the experiment 18 Wistar Albino type rats which are around 200-250 g were used. These rats were divided into 3 groups and each has 6 rats. Urethra was marked till external meatus with 18G sting. To the 1st group, not any drug was given. To the 2nd group, for 3 weeks saline (1 cc) was given into urethra. To the 3rd group for 3 weeks uttarbasti (1 cc) was applied into urethra. At the end of the 3rd week, all the groups were decapitated. They were taken into histopathological search with their penis tissue and urethra.
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- 2012
4. Improvement of monosymptomatic enuresis after adenotonsillectomy in children with obstructive sleep apnea syndrome
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Ahmet Gokce, Gökçe, Ahmet, Sundus Aslan, Fatih Rustu Yalcinkaya, Mursel Davarci, Yusuf Selim Kaya, Nazan Savas, Sadik Gorur, Safak Dagli, Ahmet Namik Kiper, Mevlana Derya Balbay, Hatay Mustafa Kemal Üniversitesi, Gokce, A, Aslan, S, Yalcinkaya, FR, Davarci, M, Kaya, YS, Savas, N, Gorur, S, Dagli, S, Kiper, AN, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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stomatognathic system ,General & Internal Medicine ,Key words: Monosymptomatic enuresis,obstructive sleep apnea,adenotonsillectomy ,General Medicine ,nervous system diseases ,respiratory tract diseases ,Cerrahi - Abstract
Aim: To investigate the prevalence of monosymptomatic enuresis (ME) in children diagnosed with obstructive sleep apnea syndrome (OSAS) and the rate of resolution or improvement in enuresis following adenotonsillectomy. Materials and methods: We retrospectively reviewed the charts of 541 consecutive patients who underwent adenotonsillectomy for OSAS secondary to adenotonsillar hypertrophy between January 2005 and January 2009. All of the charts for patients between 5 and 18 years of age at the time of surgery (n = 398) were included in the study. After reviewing the charts, the families were contacted by telephone. Those patients who had shown preoperative symptoms of enuresis were questioned to determine whether there had been any change in their complaints postoperatively. Results: Of the 398 patients whose records were reviewed, 98 were excluded from this study because of incomplete records. The incidence of ME in the study group (n = 300) prior to adenotonsillectomy was 30.7% (92 patients). Among these 92 patients, 64 (69.6%) were male and 28 (30.4%) were female (P = 0.001). The parents of 46 of these 92 patients agreed to allow their children to participate in the study. In 46 patients, 26 (56.5%) had complete resolution, 8 (17.4%) had a partial improvement, and 12 (26.1%) had no change in enuresis following adenotonsillectomy. Patients with OSAS had a 2.38-fold higher risk of ME (odds ratio 2.38, 95% confi dence interval 1.60 to 3.53, P = 0.001). Conclusion: Children with OSA symptoms have a high rate of monosymptomatic enuresis. Relief of OSA symptoms also resulted in the complete resolution or partial improvement of ME in more than two-thirds of patients. In the diff erential diagnosis of a child presenting with enuresis, OSAS should be kept in mind and, conversely, the presence of enuresis should be investigated in children presenting with OSA symptoms.
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- 2014
5. Hereditary Behavior of Varicocele
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Ahmet Gokce, Gökçe, Ahmet, Muersel Davarci, Fatih Ruetue Yalcinkaya, Esref Oguz Guven, Yusuf Selim Kaya, Mehmet Rami Helvaci, Mevlana Derya Balbay, Gokce, A, Davarci, M, Yalcinkaya, FR, Guven, EO, Kaya, YS, Helvaci, MR, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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Adult ,Male ,Infertility ,medicine.medical_specialty ,Adolescent ,Turkey ,Urology ,Endocrinology, Diabetes and Metabolism ,Varicocele ,Testicular pain ,Physical examination ,Endocrinology ,Scrotum ,Prevalence ,medicine ,Humans ,Infertility, Male ,Gynecology ,medicine.diagnostic_test ,Obstetrics ,business.industry ,Familial risk ,medicine.disease ,Increased risk ,medicine.anatomical_structure ,Reproductive Medicine ,Cohort ,medicine.symptom ,business - Abstract
The inheritance of varicoceles and the potential transmission to first-degree relatives has rarely been investigated. In the present study, we examined the first-degree relatives of men with known varicocele to reveal the familial risk for varicocele. Of the patients with clinical varicocele who presented with infertility, testicular pain, or asymmetrical swelling of the scrotum between June 1, 2008 and May 31, 2009, 49 agreed to have their available first-degree relatives contacted for screening of varicoceles (n = 66). A cohort of 100 consecutive men who applied to the department of internal medicine between 2008 and 2009 for checkup procedure without a history of subfertility or a varicocele were used as a control population. Of the 92 first-degree relatives contacted, 66 (71.7%) decided to participate in this study. Of these 66 men, 21 (33.9%) had a palpable varicocele on physical examination. Compared with a control population (12%), the prevalence of palpable varicocele in the first-degree relatives of patients with known varicocele (33.9%) was approximately 3-fold greater (P < .005). Among the first-degree relatives, 4 (21.1%) of 19 fathers and 17 (36.2%) of 47 brothers had palpable varicocele. As a conclusion, a significant increase in varicocele prevalence is present in the first-degree relatives of men with known varicoceles. Patients should be counseled about this increased risk in male relatives of patients.
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- 2009
6. Urodynamic evaluation of acute effects of sildenafil on voiding among males with erectile dysfunction and symptomatic benign prostate
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Fatih Rustu Yalcinkaya, Mursel Davarci, Soner Akcin, Ahmet Gokce, Gökçe, Ahmet, Esref Oguz Guven, Mehmet Inci, Mevlana Derya Balbay, Yalcinkaya, FR, Davarci, M, Akcin, S, Gokce, A, Guven, EO, Inci, M, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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General & Internal Medicine ,cardiovascular system ,General Medicine ,urologic and male genital diseases ,respiratory tract diseases - Abstract
Conclusion: Based on the study findings, we suggest that sildenafil has an effect on micturition in the short term. However, to determine the role of sildenafil in the treatment of BPH/LUTS, further studies with larger patient groups are needed.
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- 2012
7. A new anthropometric measurement of penile length and its relation to second and fourth digital lengths
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Mursel Davarci, Ahmet Gokce, Gökçe, Ahmet, Fatih Rustu Yalcinkaya, Yusuf Selim Kaya, Ebru Turhan, Murat Tutanc, Yunus Dogramaci, Mevlana Derya Balbay, Hatay Mustafa Kemal Üniversitesi, Davarci, M, Gokce, A, Yalcinkaya, FR, Kaya, YS, Turhan, E, Tutanc, M, Dogramaci, Y, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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General & Internal Medicine ,mental disorders ,Key words: Penis size,digit length,somatometric parameter ,General Medicine ,psychological phenomena and processes ,Cerrahi - Abstract
Amaç: Ürogenital sistem farklılaşmasını kontrol eden Hox genleri parmakların gelişimini de kontrol etmektedir. Bu çalışmada penis uzunluğu ile ikinci ve dördüncü parmakaların uzunlukları arasındaki ilişki değerlendirildi. Yöntem ve gereç: Bu çalışmaya doğu akdeniz bölgesindeki ilkokul çağındaki toplam 1028 Türk erkek çocuğu dahil edilmiştir. Vücut kitle indeksini hesap edebilmek için ağırlık ve uzunlukları ölçülmüştür. Penis uzunlukları gevşek ve gerilmiş halde ölçülmüştür. Sağ el ikinci ve dördüncü parmakların uzunlukları ölçülmüştür. İstatiksel ölçümler deskriptif istatistik ve Pearson korrelasyon analizi ile yapılmıştır. Bulgular: Aşağıdaki karşılaştırmalar arasında anlamlı korelasyon tespit edilmiştir: ikinci parmak uzunluğu ile gevşek ve gerilmiş penis uzunluğu (r = 0,166 and r = 0,276, sırasıyla; P < 0,01); dördüncü parmak uzunluğu ile gevşek ve gerilmiş penis uzunluğu (r = 0,174 and r = 0,287, sırasıyla; P < 0,01). 2D:4D oranı ile gevşek ve gerilmiş penis uzunluğu arasında anlamlı korelasyon bulunmamıştır (r = –0,013; P = 0,668, r = –0,018; P = 0,565). Sonuç: Sonuç olarak, çalışmamızdaki pozitif korelasonlar yeni bir bulgudur ve içerisinde daha başka klinik anlamlar içerebilir., Aim: The development of digits is under the control of Hox genes, which also control the differentiation of the urogenital system. In the present study we evaluated the association between penile length and lengths of the second and fourth digits. Materials and methods: In this study, 1028 Turkish male primary school children from the Eastern Mediterranean Region of Turkey were included. Weight and height measurements were obtained in order to calculate the body mass index (BMI). Flaccid and stretched length of the penis was measured. The lengths of the second and fourth digits of the right hands were measured. Statistical analyses were performed with descriptive statistics and Pearson correlation analysis. Results: A significant correlation was found between the following parameters: the length of the second digit with flaccid and stretched length of the penis (r = 0.166 and r = 0.276, respectively; P < 0.01); and the length of the fourth digits with flaccid and stretched length of the penis (r = 0.174 and r = 0.287, respectively; P < 0.01). No significant correlation of 2D:4D ratio was found with flaccid and stretched length of the penis (r = –0.013; P = 0.668, r = –0.018; P = 0.565, respectively). Conclusion: The positive correlations in our study are a novel finding and may have further clinical implications.
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- 2012
8. The impact of NIH-IV prostatitis on early post-operative outcomes of transurethral resection of the prostate in patients with symptomatic benign prostate hyperplasia
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Fatih Rustu Yalcinkaya, Ahmet Gokce, Gökçe, Ahmet, Mursel Davarci, Esref Oguz Guven, Mehmet Inci, Suleyman Baris Kartal, Ali Ayyildiz, Mevlana Derya Balbay, Yalcinkaya, FR, Gokce, A, Davarci, M, Guven, EO, Inci, M, Kartal, SB, Ayyildiz, A, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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General & Internal Medicine ,urologic and male genital diseases - Abstract
Conclusion: NIH-IV chronic prostatitis shows negative effects on the subjective post-operative results and recatheterization frequency of BPH patients that have undergone TURP.
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- 2011
9. Penile Mondor's disease can be effectively treated with the use of an acetyl salicylic acid and pentoxifylline combination
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Mursel Davarci, Esref Oguz Guven, Ahmet Gokce, Gökçe, Ahmet, Fatih Rustu Yalcinkaya, Ahmet Namik Kiper, Mevlana Derya Balbay, Davarci, M, Guven, EO, Gokce, A, Yalcinkaya, FR, Kiper, AN, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
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General & Internal Medicine ,General Medicine - Abstract
Conclusion: We think that the ASA and pentoxifylline protocol, which is also used for the treatment of thrombotic events in other parts of the body, helps to resolve penile Mondor's disease in a shorter time compared to previous treatment protocols. Further randomized controlled studies are needed for a definitive decision.
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- 2010
10. Protective Effect of Vitamin E and Melatonin Against Radiation Induced Damage in Testes of Rats
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F. R. Yalcinkaya, A. Gokce, Gökçe, Ahmet, E. O. Guven, M. Davarci, G. Cikim, H. Yekeler, M. D. Balbay, Yalcinkaya, FR, Gokce, A, Guven, EO, Davarci, M, Cikim, G, Yekeler, H, Balbay, MD, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, and Gökçe, Ahmet
- Abstract
To investigate the effects of vitamin E and melatonin on gamma ray induced damage in testes of rats. A total of 40 Wistar type rats were divided into 4 groups, each including 10 rats. Total body radiation was applied to the first 3 groups with 90 cm, 90% isodose curve using Cobalt 60 apparatus. The period of exposure time was 11 min 30 see and a total of 360 cGy gamma radiation was administered in each session. Following radiation exposure, intraperitoneal injection of vitamin E (100 mg/kg/day), melatonin (100 mg/kg/day), 0.9% saline (100 mg/kg/day) were done in group 1-3, respectively. Group 4 was the control group and intraperitoneal 0.9% saline (100 mg/kg/day) was administered without any radiation. Five days after the procedure testes were removed and analyzed to measure Malondialdehyde (MDA) levels and degree of histopathological injury. Tissue MDA level measured in rats receiving melatonin did not show significant difference when compared to control group (p>0.05). Similarly, there was no significant tissue injury on histopathological examination between melatonin administered and control groups. However, compared to the control group both tissue MDA level and tissue injury were found to be significantly increased in groups, which received vitamin E and 0.9% saline solution (p
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- 2009
11. Relationship between endothelial dysfunction and nocturia with benign prostatic hyperplasia.
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Inci M, Sarli B, Davarci M, Yalcinkaya FR, Rifaioğlu MM, Davran R, Arica S, Motor S, and Demirbaş O
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- Adult, Aged, Brachial Artery physiopathology, Case-Control Studies, Comorbidity, Humans, Male, Middle Aged, Nocturia epidemiology, Organ Size, Prostatic Hyperplasia epidemiology, Regional Blood Flow physiology, Risk Factors, Endothelium, Vascular physiopathology, Nocturia physiopathology, Prostate pathology, Prostatic Hyperplasia physiopathology
- Abstract
Objective: There are limited data on whether there is an association between nocturia, benign prostatic hyperplasia (BPH) and endothelial dysfunction. The aim of the present study was to evaluate whether there is an association between nocturia and endothelial dysfunction in patients with BPH., Material and Methods: Forty-two men with a diagnosis of BPH and 42 age-matched controls were enrolled. All patients were assessed for frequency and duration of nocturia, and prostate volume, completed the International Prostate Symptom Score (IPSS) questionnaire, and underwent brachial flow-mediated dilatation (FMD) evaluation., Results: There was a negative correlation between FMD and frequency of nocturia (r = -0.879, p < 0.0001). Moreover, there was a negative correlation between duration of nocturia and FMD (r = -0.890, p < 0.0001). In addition, FMD was significantly decreased in the BPH group compared with the control group (6.0 ± 0.09 to 7.8 ± 0.10%) (p = 0.0001)., Conclusion: In patients with BPH, nocturia is associated with endothelial dysfunction and may be an insidious risk factor for cardiovascular disease.
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- 2013
- Full Text
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12. Metastatic prostate adenocarcinoma presenting as supraclavicular lymphadenopathy: a report of two cases.
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Davarci M, Gokce A, Guven EO, Yalcinkaya FR, Esen H, and Sevinc A
- Abstract
Clinical examination is very important in the practice of medicine. In patients presenting with a supraclavicular mass, a number of diseases including cancer should be ruled out. Two patients who presented with a bulky left supraclavicular mass were evaluated. Their medical history revealed complaints attributed to lower urinary tract infection. We performed histopathological examination of the lymph nodes with radiological evaluation of the thorax and abdomen. The final diagnoses were prostate cancer in both patients. It should always be kept in mind that prostate cancer is the most frequent cancer in elderly men, and although very unusual, the presenting finding can be cervical or supraclavicular lymphadenopathy; thus clinicians should be aware of urological examinations in such cases.
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- 2012
- Full Text
- View/download PDF
13. The effect of ankaferd to stop bleeding in experimental partial nephrectomy.
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Yalcinkaya FR, Kerem M, Guven EO, Gokce A, and Davarci M
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- Animals, Blood Urea Nitrogen, Creatinine blood, Rats, Rats, Wistar, Blood Loss, Surgical prevention & control, Cellulose, Oxidized administration & dosage, Hemostatics administration & dosage, Nephrectomy, Plant Extracts administration & dosage
- Abstract
Aims: In kidney surgery, bleeding is one of the most important issues. In partial nephrectomy, as a "blood stopper", we used surgycell and ankaferd which is used traditionally in Turkish medicine., Material and Methods: 24 Wistar-Albino rats were grouped randomly. Laparotomy was performed in the first group, sham group. In the second group, partial nephrectomy was performed to lower-kidney pole and then, serum physiology was given to the lower part of the kidney. In the third group, partial nephrectomy was performed and surgycell was given over the kidney. In the fourth group, partial nephrectomy was performed and then ABS was applied. In all groups, the gauze was weighted on sensitive lift before and after the operation in order to determine the amount of bleeding. After the subjects were left alive for 5 hours, the levels of blood urea, and creatinine and kidney histopathology were evaluated., Results: No meaningful difference between the groups was found as for the levels of blood urea, and creatinine and the kidney histopathology. Bleeding amount was diminished significantly in the group 4, to which ankaferd was applied., Conclusion: Ankaferd is a substance which can be used effectively for controlling acute bleeding in kidney surgery (Tab. 2, Ref. 19). Full Text in free PDF www.bmj.sk.
- Published
- 2011
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