Search

Your search keyword '"Yager, Jerome"' showing total 456 results
Start Over Author "Yager, Jerome"
456 results on '"Yager, Jerome"'

3. What's the harm? Results of an active surveillance adverse event reporting system for chiropractors and physiotherapists.

Author

Pohlman, Katherine A., Funabashi, Martha, O'Beirne, Maeve, Cassidy, J. David, Hill, Michael D., Hurwitz, Eric L., Kawchuk, Gregory, Mior, Silvano, Ibrahim, Quazi, Thiel, Haymo, Westaway, Michael, Yager, Jerome, and Vohra, Sunita

Subjects
WATCHFUL waiting, OFFICES, BACKACHE, CHIROPRACTORS, PHYSICAL therapists
Abstract

This prospective, community-based, active surveillance study aimed to report the incidence of moderate, severe, and serious adverse events (AEs) after chiropractic (n = 100) / physiotherapist (n = 50) visit in offices throughout North America between October-2015 and December-2017. Three content-validated questionnaires were used to collect AE information: two completed by the patient (pre-treatment [T0] and 2–7 days post-treatment [T2]) and one completed by the provider immediately post-treatment [T1]. Any new or worsened symptom was considered an AE and further classified as mild, moderate, severe or serious. From the 42 participating providers (31 chiropractors; 11 physiotherapists), 3819 patient visits had complete T0 and T1 assessments. The patients were on average 50±18 years of age and 62.5% females. Neck/back pain was the most common presenting condition (70.0%) with 24.3% of patients reporting no condition/preventative care. From the patients visits with a complete T2 assessment (n = 2136 patient visits, 55.9%), 21.3% reported an AE, of which: 7.9% were mild, 6.2% moderate, 3.7% severe, 1.5% serious, and 2.0% had missing severity rating. The most common symptoms reported with moderate or higher severity were discomfort/pain, stiffness, difficulty walking and headache. This study provides valuable information for patients and providers regarding incidence and severity of AEs following patient visits in multiple community-based professions. These findings can be used to inform patients of what AEs may occur and future research opportunities can focus on mitigating common AEs. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

6. Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence.

Author

Fullerton, Heather J, deVeber, Gabrielle A, Hills, Nancy K, Dowling, Michael M, Fox, Christine K, Mackay, Mark T, Kirton, Adam, Yager, Jerome Y, Bernard, Timothy J, Hod, Eldad A, Wintermark, Max, Elkind, Mitchell SV, and VIPS Investigators

Subjects
VIPS Investigators, Humans, Brain Ischemia, Cerebral Arterial Diseases, Recurrence, Peroxidase, Tumor Necrosis Factor-alpha, C-Reactive Protein, Serum Amyloid A Protein, Risk Factors, Adolescent, Child, Child, Preschool, Female, Male, Stroke, Biomarkers, C-reactive protein, Cox proportional hazards models, biomarkers, inflammation, serum amyloid A protein, stroke, Prevention, Pediatric, Brain Disorders, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurosciences, Neurology & Neurosurgery
Abstract

Background and purposeAmong children with arterial ischemic stroke (AIS), those with arteriopathy have the highest recurrence risk. We hypothesized that arteriopathy progression is an inflammatory process and that inflammatory biomarkers would predict recurrent AIS.MethodsIn an international study of childhood AIS, we selected cases classified into 1 of the 3 most common childhood AIS causes: definite arteriopathic (n=103), cardioembolic (n=55), or idiopathic (n=78). We measured serum concentrations of high-sensitivity C-reactive protein, serum amyloid A, myeloperoxidase, and tumor necrosis factor-α. We used linear regression to compare analyte concentrations across the subtypes and Cox proportional hazards models to determine predictors of recurrent AIS.ResultsMedian age at index stroke was 8.2 years (interquartile range, 3.6-14.3); serum samples were collected at median 5.5 days post stroke (interquartile range, 3-10 days). In adjusted models (including age, infarct volume, and time to sample collection) with idiopathic as the reference, the cardioembolic (but not arteriopathic) group had higher concentrations of high-sensitivity C-reactive protein and myeloperoxidase, whereas both cardioembolic and arteriopathic groups had higher serum amyloid A. In the arteriopathic (but not cardioembolic) group, higher high-sensitivity C-reactive protein and serum amyloid A predicted recurrent AIS. Children with progressive arteriopathies on follow-up imaging had higher recurrence rates, and a trend toward higher high-sensitivity C-reactive protein and serum amyloid A, compared with children with stable or improved arteriopathies.ConclusionsAmong children with AIS, specific inflammatory biomarkers correlate with cause and-in the arteriopathy group-risk of stroke recurrence. Interventions targeting inflammation should be considered for pediatric secondary stroke prevention trials.

Published
2016

7. Risk of Recurrent Arterial Ischemic Stroke in Childhood

Author

Fullerton, Heather J, Wintermark, Max, Hills, Nancy K, Dowling, Michael M, Tan, Marilyn, Rafay, Mubeen F, Elkind, Mitchell SV, Barkovich, A James, deVeber, Gabrielle A, Plumb, Patricia A, Benedict, Susan L, Bernard, Timothy J, Fox, Christine K, Friedman, Neil R, Lo, Warren D, Ichord, Rebecca N, Mackay, Mark T, Kirton, Adam, Hernandez-Chavez, Marta I, Humphreys, Peter, Jordan, Lori C, Sultan, Sally, Rivkin, Michael J, Titomanlio, Luigi, Kovacevic, Gordana S, Yager, Jerome Y, Amlie-Lefond, Catherine, Dlamini, Nomazulu, Condie, John, Yeh, Ann, Kneen, Rachel, Bjornson, Bruce, Pergami, Paola, Zou, Li Ping, Elbers, Jorina M, Abdalla, Abdalla, Chan, Anthony K, Farooq, Osman, Lim, Mingming J, Carpenter, Jessica L, Pavlakis, Steven, Wong, Virginia C, and Forsyth, Robert

Subjects
Paediatrics, Biomedical and Clinical Sciences, Brain Disorders, Pediatric, Stroke, Prevention, Neurosciences, Atherosclerosis, Adolescent, Brain Ischemia, Cerebral Arterial Diseases, Child, Child, Preschool, Cohort Studies, Female, Follow-Up Studies, Humans, Infant, Internationality, Male, Prospective Studies, Recurrence, Risk Factors, child, pediatrics, risk factor, stroke, vaccination, VIPS Investigators, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurology & Neurosurgery, Clinical sciences, Allied health and rehabilitation science
Abstract

Background and purposePublished cohorts of children with arterial ischemic stroke (AIS) in the 1990s to early 2000s reported 5-year cumulative recurrence rates approaching 20%. Since then, utilization of antithrombotic agents for secondary stroke prevention in children has increased. We sought to determine rates and predictors of recurrent stroke in the current era.MethodsThe Vascular Effects of Infection in Pediatric Stroke (VIPS) study enrolled 355 children with AIS at 37 international centers from 2009 to 2014 and followed them prospectively for recurrent stroke. Index and recurrent strokes underwent central review and confirmation, as well as central classification of causes of stroke, including arteriopathies. Other predictors were measured via parental interview or chart review.ResultsOf the 355 children, 354 survived their acute index stroke, and 308 (87%) were treated with an antithrombotic medication. During a median follow-up of 2.0 years (interquartile range, 1.0-3.0), 40 children had a recurrent AIS, and none had a hemorrhagic stroke. The cumulative stroke recurrence rate was 6.8% (95% confidence interval, 4.6%-10%) at 1 month and 12% (8.5%-15%) at 1 year. The sole predictor of recurrence was the presence of an arteriopathy, which increased the risk of recurrence 5-fold when compared with an idiopathic AIS (hazard ratio, 5.0; 95% confidence interval, 1.8-14). The 1-year recurrence rate was 32% (95% confidence interval, 18%-51%) for moyamoya, 25% (12%-48%) for transient cerebral arteriopathy, and 19% (8.5%-40%) for arterial dissection.ConclusionsChildren with AIS, particularly those with arteriopathy, remain at high risk for recurrent AIS despite increased utilization of antithrombotic agents. Therapies directed at the arteriopathies themselves are needed.

Published
2016

8. Contributors

Author

Al-Dujaili, Emad A.S., primary, Amalraj, Augustine, additional, Armstrong, Edward A., additional, Ayati, Zahra, additional, Badmaev, Vladimir, additional, Balakrishnan, Arun, additional, Banerjee, Sharmistha, additional, Benson, Sarah, additional, Bethapudi, Bharathi, additional, Bureau, Yves, additional, Carriere, Autumn, additional, Casola, Brendan, additional, Cernovsky, Zack, additional, Chalichem, Nehru Sai Suresh, additional, Chandradhara, Divya, additional, Chang, Dennis, additional, Chaudhari, Kaustubh S., additional, Chiu, Simon S., additional, Copen, John, additional, Csupor, Dezső, additional, Sharma Datta, Hema, additional, Siraj Daud, Anwar, additional, Dkhar, Preeticia, additional, Dutta, Sayanta, additional, Emami, Seyed Ahmad, additional, Garg, Neha, additional, Gauci, Sarah, additional, Ghosh, Dilip, additional, Ghosh, Rohit, additional, Ghosh, Souvik, additional, Ghosh, Sumit, additional, Gopi, Sreeraj, additional, Guillemin, Gilles J., additional, Haldar, Swati, additional, Henein, Marina, additional, Houghton, Christine A., additional, Husni, Mariwan, additional, Kanjilal, Satyajyoti, additional, Karamacoska, Diana, additional, Katiyar, Chandra Kant, additional, Khairy, Mostafa, additional, Khazaeipool, Zahra, additional, Kuca, Kamil, additional, Kumar, Viney, additional, Ladak, Zeenat, additional, Lahiri, Debrupa, additional, Lui, Ed, additional, Macpherson, Helen, additional, Martin, Laura, additional, McEwen, Bradley J., additional, Morde, Abhijeet, additional, Mottaghipisheh, Javad, additional, Mundkinajeddu, Deepak, additional, Murugan, Sasikumar, additional, Narwaria, Avinash, additional, Ou, Ruchong, additional, Padigaru, Muralidhara, additional, Patwardhan, Bhushan, additional, Perry, Naomi, additional, Pipingas, Andrew, additional, Prajapati, Pradeep Kumar, additional, Purusothaman, Divya, additional, Raheb, Hana, additional, Rathi, Preeti, additional, Rosenfeldt, Frank, additional, Rowsell, Renee, additional, Roy, Partha, additional, Saini, Saakshi, additional, Sapkal, Nidhi Prakash, additional, Schoenlau, Frank, additional, Scholey, Andrew, additional, Shad, Mujeeb, additional, Sharma, Ramesh, additional, Sharma, Rohit, additional, Sharma, Vineet, additional, Shrivastava, Siddhansh, additional, Sieffien, Weam, additional, Sil, Parames C., additional, Sound, Ruby, additional, Stockton, Angela V.E., additional, Stough, Con, additional, Teegala, Ramesh, additional, Terpstra, Kristen, additional, Thakurdesai, Prasad Arvind, additional, Tóth, Barbara, additional, Varghese, Josh, additional, Verma, Deepanshu, additional, Verma, Nikhil, additional, Chandrasiri Waliwita, W.A.L., additional, White, David J., additional, Woodbury-Farina, Michel, additional, Kant Yadav, Jay, additional, Yager, Jerome Y., additional, Young, Lauren M., additional, and Zangara, Andrea, additional

Published
2021
Full Text
View/download PDF

9. Glucosinolates

Author

Ladak, Zeenat, primary, Khairy, Mostafa, additional, Armstrong, Edward A., additional, and Yager, Jerome Y., additional

Published
2021
Full Text
View/download PDF

13. Contributors

Author

Bertini, Enrico, primary, Bingham, Adrienne, additional, Chau, Vann, additional, Cilio, Maria Roberta, additional, D’Amico, Adele, additional, de Vries, Linda S., additional, Ferriero, Donna M., additional, Gano, Dawn, additional, Glass, Torin J.A., additional, Kabani, Nazia, additional, Kasdorf, Ericalyn, additional, Kaufman, David, additional, Kimberlin, David W., additional, Laptook, Abbot R., additional, Le Pichon, Jean-Baptiste, additional, Marlow, Neil, additional, McLean, Claire, additional, Noori, Shahab, additional, Perlman, Jeffrey M., additional, Pisani, Francesco, additional, Riordan, Sean M., additional, Sánchez, Pablo J., additional, Sands, Tristan T., additional, Seed, Michael, additional, Seri, Istvan, additional, Shapiro, Steven M., additional, Spagnoli, Carlotta, additional, Toet, Mona C., additional, Weeke, Lauren C., additional, Wei-Wu, Tai, additional, Whitelaw, Andrew, additional, Yager, Jerome Y., additional, Yap, Vivien, additional, and Zanelli, Santina, additional

Published
2019
Full Text
View/download PDF

19. Early intensive leg training to enhance walking in children with perinatal stroke: Protocol for a randomized controlled trial

Author

Hurd, Caitlin, Livingstone, Donna, Brunton, Kelly, Teves, Michelle, Zewdie, Ephrem, Smith, Allison, Ciechanski, Patrick, Gorassini, Monica A., Kirton, Adam, Watt, Man-Joe, Andersen, John, Yager, Jerome, and Yang, jaynie F.

Subjects
Stroke (Disease) -- Prevention, Therapeutics, Physiological -- Usage -- Physiological aspects -- Methods, Physical therapy -- Usage -- Physiological aspects -- Methods, Children -- Physiological aspects -- Usage -- Methods, Physical therapy for children -- Usage -- Physiological aspects -- Methods, Walking -- Methods -- Physiological aspects -- Usage, Health
Abstract

Background. Development of motor pathways is modulated by activity in these pathways, when they are maturing (ie, critical period). Perinatal stroke injures motor pathways, including the corticospinal tracts, reducing their [...]

Published
2017
Full Text
View/download PDF

23. Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study

Author

Banwell, Brenda, Bar-Or, Amit, Arnold, Douglas L, Sadovnick, Dessa, Narayanan, Sridar, McGowan, Melissa, O'Mahony, Julia, Magalhaes, Sandra, Hanwell, Heather, Vieth, Reinhold, Tellier, Raymond, Vincent, Thierry, Disanto, Giulio, Ebers, George, Wambera, Katherine, Connolly, Mary B, Yager, Jerome, Mah, Jean K, Booth, Fran, Sebire, Guillaume, Callen, David, Meaney, Brandon, Dilenge, Marie-Emmanuelle, Lortie, Anne, Pohl, Daniela, Doja, Asif, Venketaswaran, Sunita, Levin, Simon, MacDonald, E Athen, Meek, David, Wood, Ellen, Lowry, Noel, Buckley, David, Yim, Conrad, Awuku, Mark, Cooper, Pamela, Grand'Maison, François, Baird, J Burke, Bhan, Virender, and Marrie, Ruth Ann

Published
2011
Full Text
View/download PDF

33. Pathways of atopic disease and neurodevelopmental impairment: assessing the evidence for infant antibiotics.

Author

Volker, Elizabeth, Tessier, Carmen, Rodriguez, Nicole, Yager, Jerome, and Kozyrskyj, Anita

Subjects
ATOPY, INFANTS, ATTENTION-deficit hyperactivity disorder, NEURAL development, AUTISM spectrum disorders
Abstract

Epidemiologic studies are starting to report associations between antibiotic use in early life and neurodevelopmental disorders. Through mechanisms within the gut microbiota-brain axis, indeed, it is plausible that infant antibiotic treatment plays a role in the development of atopic disease and neurodevelopmental disorders. This narrative review summarizes and interprets published evidence on infant antibiotic use in future outcomes of atopic disease, and neurodevelopmental delay and disorders, including attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). To this end, we critically assess study bias from two main confounding factors, maternal/infant infection and infant feeding status. We also discuss common mechanisms that link atopy and neurodevelopment, and propose hypotheses related to immune activation and the gut microbiome. Atopic disease and neurodevelopmental disorders share many risk factors and biological pathways. Infant antibiotic use has been linked to both disorders and is likely a marker for prenatal or infant infection. The mediating role of breastfeeding can also not be discounted. The exploration of causal pathways along the gut-brain axis leading toward neurodevelopmental impairment is evolving and of future interest. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

40. Contributors

Author

Cantey, Joseph B., primary, Cayabyab, Rowena G., additional, Chan, Keung-kit, additional, Darras, Basil T., additional, Dastgir, Jahannaz, additional, de Vries, Linda S., additional, Eiland, Lisa, additional, Hüppi, Petra S., additional, Kasdorf, Ericalyn, additional, Kaufman, David, additional, Kimberlin, David W., additional, Laptook, Abbot R., additional, Lodygensky, Gregory A., additional, McLean, Claire W., additional, Menache, Caroline C., additional, Ment, Laura R., additional, Myers, Eliza H., additional, Noori, Shahab, additional, Perlman, Jeffrey M., additional, Sánchez, Pablo J., additional, Scher, Mark S., additional, Seri, Istvan, additional, Shapiro, Steven M., additional, Takenouchi, Toshiki, additional, Toet, Mona C., additional, Vohr, Betty R., additional, Whitelaw, Andrew, additional, Yager, Jerome Y., additional, and Zanelli, Santina, additional

Published
2012
Full Text
View/download PDF

41. Contributors

Author

Abou-Hamden, Amal, primary, Amato, Anthony A., additional, Ashwal, Stephen, additional, Axelrod, Felicia B., additional, Bale, James F., additional, Banwell, Brenda, additional, Baranano, Kristin W., additional, Barkovich, A. James, additional, Barohn, Richard J., additional, Batshaw, Mark L., additional, Ben-Sira, Liat, additional, Birnbaum, Angela K., additional, Boustany, Rose-Mary N., additional, Brooks-Kayal, Amy, additional, Brown, Lawrence W., additional, Camfield, Carol S., additional, Camfield, Peter R., additional, Casselbrant, Margaretha L., additional, Chiriboga, Claudia A., additional, Christian, Susan L., additional, Cilio, Maria Roberta, additional, Connolly, Anne M., additional, Conway, Jeannine M., additional, Cornes, Susannah, additional, Coulter, David L., additional, Cowan, Tina M., additional, Das, Soma, additional, De Vivo, Darryl C., additional, de Vries, Linda S., additional, Desai, Jay, additional, Descartes, Maria, additional, deVeber, Gabrielle, additional, DiMauro, Salvatore, additional, Dobyns, William B., additional, Dong, Qing, additional, Drake, James M., additional, Duhaime, Ann-Christine, additional, du Plessis, Adre J., additional, El-Bitar, Mohamad K., additional, Enns, Gregory M., additional, Escolar, Diana M., additional, Evans, Owen B., additional, Fatemi, S. Ali, additional, Ferriero, Donna M., additional, Filipek, Pauline A., additional, Frank, Yitzchak, additional, Fredrick, Douglas R., additional, Freeze, Hudson H., additional, Friedman, Neil R., additional, Furman, Joseph M., additional, Garg, Bhuwan P., additional, Ghosh, Debabrata, additional, Gilles, Elizabeth E., additional, Giza, Christopher C., additional, Glaser, Carol A., additional, Gleeson, Joseph G., additional, Graham, John M., additional, Gressens, Pierre, additional, Guerrini, Renzo, additional, Gupta, Nalin, additional, Hahn, Jin S., additional, Harini, Chellamani, additional, Heatwole, Chad, additional, Hirtz, Deborah G., additional, Holmes, Gregory L., additional, Holshouser, Barbara A., additional, Ichord, Rebecca N., additional, Jafar-Nejad, Paymaan, additional, Jensen, Frances E., additional, Johnston, Michael V., additional, Jordan, Lori, additional, Khakoo, Yasmin, additional, Khasraw, Mustafa, additional, Kirton, Adam, additional, Kissel, John T., additional, Klein, Ophir, additional, Knupp, Kelly, additional, Korf, Bruce R., additional, Kotagal, Suresh, additional, Leber, Steven, additional, Leppik, Ilo E., additional, Lerman-Sagie, Tally, additional, Lerner, Jason T., additional, Leshner, Robert T., additional, Leventer, Richard J., additional, Lewis, Donald W., additional, Lewis, Paul F., additional, Lichter-Konecki, Uta, additional, Limperopoulos, Catherine, additional, Louie, Janice K., additional, Luc, Quyen N., additional, MacDonald, Tobey J., additional, Makhani, Naila, additional, Malinger, Gustavo, additional, Mandelbaum, David E., additional, Marcuccilli, Charles J., additional, Maricich, Stephen M., additional, Martin, Lee J., additional, Mennella, Julie A., additional, Ment, Laura R., additional, Michelson, David J., additional, Mikhail, Fady M., additional, Millen, Kathleen J., additional, Miller, Steven P., additional, Mink, Jonathan W., additional, Mirzaa, Ghayda, additional, Mitchell, Wendy G., additional, Moodley, Manikum, additional, Morton, Lawrence D., additional, Moxley, Richard T., additional, Muppidi, Srikanth, additional, Nash, Kendall, additional, Nass, Ruth, additional, Noetzel, Michael J., additional, Nordli, Douglas R., additional, Northington, Frances J., additional, Ouvrier, Robert, additional, Packer, Roger J., additional, Packman, Seymour, additional, Parsons, Julie A., additional, Partridge, John C., additional, Pastores, Gregory M., additional, Patterson, Marc C., additional, Pellock, John M., additional, Perkin, Ronald M., additional, Rapin, Isabelle, additional, Raymond, Gerald V., additional, Rendleman, Rebecca, additional, Rho, Jong M., additional, Roddy, Sarah M., additional, Rosenthal, Stephen M., additional, Rosman, N. Paul, additional, Ross, M. Elizabeth, additional, Rust, Robert S., additional, Sanchez-Lara, Pedro A., additional, Sanger, Terence D., additional, Sanmaneechai, Oranee, additional, Schaad, Urs B., additional, Scher, Mark S., additional, Schor, Nina F., additional, Segal, Michael M., additional, Shaywitz, Bennett A., additional, Shaywitz, Sally E., additional, Sherr, Elliott H., additional, Shevell, Michael I., additional, Shinnar, Shlomo, additional, Shu, Stanford K., additional, Silverstein, Faye S., additional, Singer, Harvey S., additional, Sladky, John T., additional, Smith, Stephen A., additional, Soul, Janet S., additional, Stafstrom, Carl E., additional, Strober, Jonathan B., additional, Sullivan, Joseph, additional, Swaiman, Kenneth F., additional, Sweney, Matthew T., additional, Swoboda, Kathryn J., additional, Täuber, Martin G., additional, Taylor, Donald A., additional, Tein, Ingrid, additional, Thiele, Elizabeth A., additional, Trauner, Doris A., additional, Tuchman, Roberto, additional, Vanderver, Adeline, additional, Hirtum-Das, Michéle Van, additional, Vedanarayanan, V. Venkataraman, additional, Vexler, Zinaida S., additional, Vezina, Gilbert, additional, Scheven, Emily von, additional, Wagner, Ann, additional, Wainwright, Mark S., additional, Walkup, John T., additional, Walsh, Laurence E., additional, Wang, Ching H., additional, Wheless, James W., additional, Wolf, Nicole I., additional, Wolfe, Gil I., additional, Wu, Yvonne W., additional, Wycliffe, Nathaniel D., additional, Yager, Jerome Y., additional, Zimmer, Jennifer A., additional, Zoghbi, Huda Y., additional, and Zupanc, Mary L., additional

Published
2012
Full Text
View/download PDF

46. Contributors

Author

Cayabyab, Rowena G., primary, Chan, Keung-kit, additional, Darras, Basil T., additional, de Veber, Gabrielle, additional, Hüppi, Petra S., additional, Kaufman, David, additional, Laptook, Abbot R., additional, McLean, Claire W., additional, Menache, Caroline C., additional, Ment, Laura R., additional, Noori, Shahab, additional, Özduman, Koray, additional, Perlman, Jeffrey M., additional, Poskitt, Kenneth J., additional, Sánchez, Pablo J., additional, Scher, Mark S., additional, Seri, Istvan, additional, Shapiro, Steven M., additional, Vohr, Betty R., additional, Whitelaw, Andrew, additional, Yager, Jerome Y., additional, and Zanelli, Santina, additional

Published
2008
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results