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286 results on '"Yagami, K."'

1. Plaster technique for filling up a future entry at the suture hole in type A aortic dissection

Author

Yagami K, Mutsuga M, Fujita T, and Ishida S

Subjects
Aortic dissection, medicine.medical_specialty, Suture (anatomy), business.industry, Medicine, business, medicine.disease, Surgery
Abstract

Although the surgical technique for acute type A aortic dissection markedly improved in the last decade, perioperative mortality and morbidity rates remain dramatically high. Therefore, we introduce the novel “plaster technique” using the single interrupted suture with a felt and plastering the minimum dose of BioGlue® (Cryolife Inc., Kennesaw, GA, USA) into the suture hole in this report. We found that the plaster technique using a felt pledget and minimum dose of BioGlue is effective for fragile aortic walls, as in patients undergoing acute aortic dissection and is a simple, safe, and durable technique to strengthen the suture line.

Published
2021
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2. Temperature study of the spin-transfer switching speed from dc to 100 ps

Author

Devolder, T., Tulapurkar, A., Suzuki, Y., Chappert, C., Crozat, P., and Yagami, K.

Subjects
Electron spin -- Analysis, Magnetization -- Analysis, Copper compounds -- Magnetic properties, Iron compounds -- Magnetic properties, Physics
Abstract

The speed of the magnetization switching resulting from spin transfer in pillar-shaped CoFe/Cu/CoFe spin valves and the temperature dependence thereof is studied. The demonstration of 100-ps switching validates spin-transfer switching for fast memory applications.

Published
2005

8. Estimation of thermal durability and intrinsic critical currents of magnetization switching for spin-transfer based magnetic random access memory

Author

Yagami, K., Tulapurkar, A.A., Fukushima, A., and Suzuki, Y.

Subjects
MRAM (Computer memory) -- Research, Magnetization -- Research, Magnetoresistance -- Research, Physics
Abstract

The theoretically predicted logarithmic relationship between critical currents of spin-transfer switching and duration and injected pulsed currents is examined using giant magnetoresistive (GMR) samples with different magnetic materials. The results reveal that thermal stability is underestimated when an effective magnetic field acts on magnetic memory cells antiparallel to their magnetization.

Published
2005

48. Establishment of a cell line with phenotypes of chondrocyte from a human osteogenic sarcoma of the mandible.

Author

Yagami, Kimitoshi, Kakuta, Saburo, Tachibana, Hideharu, Kimura, Yoshitaka, Nagumo, Masao, Yagami, K, Kakuta, S, Tachibana, H, Kimura, Y, and Nagumo, M

Subjects
OSTEOSARCOMA, CELL lines, CHONDROGENESIS, PHENOTYPES, COLLAGEN, DIAGNOSTIC immunohistochemistry, BIOMINERALIZATION, ANALYSIS of variance, ANIMAL experimentation, CANCER, CARTILAGE cells, CELL division, CELLS, COMPARATIVE studies, GLYCOPROTEINS, KARYOTYPES, MANDIBLE, RESEARCH methodology, MEDICAL cooperation, MICE, RESEARCH, EVALUATION research
Abstract

We have succeeded in transplanting a human osteogenic sarcoma of the mandible into athymic mice. The transplanted tumor showed marked chondrogenesis and mineralization. Recently, a cell line (USAC) with phenotypes of chondrocyte has been established from the transplanted tumor. USAC cells were stellate or spindle-shaped in sparse culture, but polygonal or spherical at sub-confluency to confluency. In long-term culture, the cells were condensed and calcified nodules were formed. Production of types I, II and X collagen were detected by immunohistochemical staining and Western blot analysis. Type I collagen was strongly expressed in the stellate or spindle-shaped cells. Although type II collagen was usually present in all cells during culture, it was strongly stained in polygonal cells at confluency. Type X collagen was seen in large polygonal cells around calcified nodules. Marked [35S]-sulfate uptake and metachromasia were seen at the confluent stage and in the nodule. The cells around the nodules were positive for alkaline phosphatase, and the center of the nodules was stained with alizarin red. The potentiality of cartilage formation was confirmed by in vivo experiments using a diffusion chamber in athymic mice. These observations indicate that USAC cells maintain characteristics of chondrocyte progenitor cells and thus may serve as a useful model to study the sequential events of chondrogenesis and the process of morbid endochondral calcification. This experiment also demonstrated that transplantation of tumor tissue into athymic mice is a convenient strategy for establishment of a cell line. [ABSTRACT FROM AUTHOR]

Published
2000
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50. Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice.

Author

Yanai, K, Saito, T, Kakinuma, Y, Kon, Y, Hirota, K, Taniguchi-Yanai, K, Nishijo, N, Shigematsu, Y, Horiguchi, H, Kasuya, Y, Sugiyama, F, Yagami, K i, Murakami, K, and Fukamizu, A

Abstract

Renin plays a key role in controlling blood pressure through its specific cleavage of angiotensinogen to generate angiotensin I (AI). Although possible existence of the other angiotensin forming enzymes has been discussed to date, its in vivo function remains to be elucidated. To address the contribution of renin, we generated renin knockout mice. Homozygous mutant mice show neither detectable levels of plasma renin activity nor plasma AI, lowered blood pressure 20-30 mm Hg less than normal, increased urine and drinking volume, and altered renal morphology as those observed in angiotensinogen-deficient mice. We recently found the decreased density in granular layer cells of hippocampus and the impaired blood-brain barrier function in angiotensinogen-deficient mice. Surprisingly, however, such brain phenotypes were not observed in renin-deficient mice. Our results demonstrate an indispensable role for renin in the circulating angiotensin generation and in the maintenance of blood pressure, but suggest a dispensable role for renin in the blood-brain barrier function.

Published
2000

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