1. Racial-ethnic diversity in ambulatory blood pressure monitoring in children with chronic kidney disease
- Author
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Pagi, Reut, Yadin, Ora, Wesseling-Perry, Katherine, Norris, Keith, and Laster, Marciana Lee
- Subjects
Biomedical and Clinical Sciences ,Cardiovascular Medicine and Haematology ,Clinical Research ,Pediatric ,Cardiovascular ,Hypertension ,Kidney Disease ,Evaluation of treatments and therapeutic interventions ,6.1 Pharmaceuticals ,Adult ,Humans ,Child ,Blood Pressure Monitoring ,Ambulatory ,Circadian Rhythm ,Blood Pressure ,Renal Insufficiency ,Chronic ,Chronic kidney disease ,Ambulatory blood pressure monitoring ,Ethnic groups ,Paediatrics and Reproductive Medicine ,Urology & Nephrology ,Clinical sciences ,Paediatrics - Abstract
BackgroundBlack adults with chronic kidney disease (CKD) have higher rates of hypertension as compared to White adults with CKD. Little is known of how race and ethnicity associate with the prevalence of hypertension in pediatric CKD patients. The aim was to compare ambulatory blood pressure monitoring (ABPM) results for patients with CKD enrolled in the Chronic Kidney Disease in Children (CKiD) study across racial-ethnic groups.MethodsPatients from the CKiD study who identified as non-Hispanic White, non-Hispanic Black, or Hispanic were included to analyze differences in ABPM results across these racial-ethnic groups. The outcomes were fitted using 3 progressively adjusted models.ResultsThis study included 501 CKiD participants with at least one successful ABPM study. Compared to White participants, Black participants had 4.2 mmHg higher mean sleep systolic blood pressure and 2.7 mmHg higher mean sleep diastolic blood pressure (p = 0.001 and p = 0.004, respectively). Additionally, Black participants had higher odds of abnormal wake systolic load (OR 1.88, 1.21-2.91, p = 0.005), wake diastolic load (OR 1.68, 1.03-2.73, p = 0.04), sleep systolic load (OR 2.19, 1.36-3.5, p = 0.001), sleep diastolic load (OR 2.01, 1.28-3.15, p = 0.002), systolic non-dipping (OR 2.02, 1.31-3.10, p = 0.001), and diastolic non-dipping (OR 2.69, 1.60-4.51, p
- Published
- 2023