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Your search keyword '"Yadav, Sumeet K."' showing total 14 results
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14 results on '"Yadav, Sumeet K."'

4. A Contemporary Review of Blood Transfusion in Critically Ill Patients.

Author

Yadav, Sumeet K., Hussein, Guleid, Liu, Bolun, Vojjala, Nikhil, Warsame, Mohamed, El Labban, Mohamad, Rauf, Ibtisam, Hassan, Mohamed, Zareen, Tashfia, Usama, Syed Muhammad, Zhang, Yaqi, Jain, Shika M., Surani, Salim R., Devulapally, Pavan, Bartlett, Brian, Khan, Syed Anjum, and Jain, Nitesh Kumar

Subjects
RED blood cell transfusion, PREOPERATIVE risk factors, ACUTE coronary syndrome, BLOOD platelet transfusion, BLOOD transfusion
Abstract

Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and coagulopathy with deficiency of single or multiple coagulation components such as platelets or coagulation factors. Nevertheless, the practice of transfusion in critically ill patients has been controversial mainly due to a lack of evidence and the need to consider the appropriate clinical context for transfusion. Further, transfusion carries many risk factors that must be balanced with benefits. Therefore, transfusion practice in ICU patients has constantly evolved, and we endeavor to present a contemporary review of transfusion practices in this population guided by clinical trials and expert guidelines. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Plasmapheresis in the ICU.

Author

Hussein, Guleid, Liu, Bolun, Yadav, Sumeet K., Warsame, Mohamed, Jamil, Ramsha, Surani, Salim R., and Khan, Syed A.

Subjects
PLASMA exchange (Therapeutics), PLASMAPHERESIS, CRITICAL care medicine, SALVAGE therapy, DISEASE progression
Abstract

Therapeutic plasma exchange (TPE) is a treatment paradigm used to remove harmful molecules from the body. In short, it is a technique that employs a process that functions partially outside the body and involves the replacement of the patient's plasma. It has been used in the ICU for a number of different disease states, for some as a first-line treatment modality and for others as a type of salvage therapy. This paper provides a brief review of the principles, current applications, and potential future directions of TPE in critical care settings. [ABSTRACT FROM AUTHOR]

Published
2023
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8. Clinical Outcomes and Prognostic Factors in Triple-Negative Invasive Lobular Carcinoma of the Breast

Author

Joshi, Utsav, primary, Budhathoki, Pravash, additional, Gaire, Suman, additional, Yadav, Sumeet K., additional, Shah, Anish, additional, Adhikari, Anurag, additional, Choong, Grace, additional, Couzi, Rima, additional, Giridhar, Karthik, additional, Leon-Ferre, Roberto, additional, Boughey, Judy C., additional, Hieken, Tina J., additional, Mutter, Robert, additional, Ruddy, Kathryn J., additional, Haddad, Tufia C., additional, Goetz, Matthew P., additional, Couch, Fergus J., additional, and Yadav, Siddhartha, additional

Published
2023
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14. Clinical Outcomes and Prognostic Factors in Triple-Negative Invasive Lobular Carcinoma of the Breast.

Author

Joshi U, Budhathoki P, Gaire S, Yadav SK, Shah A, Adhikari A, Choong G, Couzi R, Giridhar K, Leon-Ferre R, Boughey JC, Hieken TJ, Mutter R, Ruddy KJ, Haddad TC, Goetz MP, Couch FJ, and Yadav S

Abstract

Purpose: Triple-negative invasive lobular carcinoma (TN-ILC) of breast cancer is a rare disease and the clinical outcomes and prognostic factors are not well-defined. Methods: Women with stage I-III TN-ILC or triple-negative invasive ductal carcinoma (TN-IDC) of the breast undergoing mastectomy or breast-conserving surgery between 2010 and 2018 in the National Cancer Database were included. Kaplan-Meier curves and multivariate Cox proportional hazard regression were used to compare overall survival (OS) and evaluate prognostic factors. Multivariate logistic regression was performed to analyze the factors associated with pathological response to neoadjuvant chemotherapy. Results: The median age at diagnosis for women with TN-ILC was 67 years compared to 58 years in TN-IDC (p<0.001). There was no significant difference in the OS between TN-ILC and TN-IDC in multivariate analysis (HR 0.96, p=0.44). Black race and higher TNM stage were associated with worse OS, whereas receipt of chemotherapy or radiation was associated with better OS in TN-ILC. Among women with TN-ILC receiving neoadjuvant chemotherapy, the 5-year OS was 77.3% in women with a complete pathological response (pCR) compared to 39.8% in women without any response. The odds of achieving pCR following neoadjuvant chemotherapy were significantly lower in women with TN-ILC compared to TN-IDC (OR 0.53, p<0.001). Conclusion: Women with TN-ILC are older at diagnosis but have similar OS compared to TN-IDC after adjusting for tumor and demographic characteristics. Administration of chemotherapy was associated with improved OS in TN-ILC, but women with TN-ILC were less likely to achieve complete response to neoadjuvant therapy compared to TN-IDC.

Published
2023
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