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Your search keyword '"Yabe, Shizuka"' showing total 24 results
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24 results on '"Yabe, Shizuka"'

8. A rapid screening method for Panton-Valentine leucocidin-positive community-acquired methicillin-resistant Staphylococcus aureus belonging to multilocus sequence type 30 and its related clone using a combination of multiplex PCR and pulsed-field gel electrophoresis

Author

Reva, Ivan, Higuchi, Wataru, Takano, Tomomi, Singur, Olga, Ozaki, Kyoko, Isobe, Hirokazu, Yabe, Shizuka, Saito, Kohei, Baranovich, Tatiana, Enany, Symaa, Otsuka, Taketo, Potapov, Vladimir, Nishiyama, Akihito, and Yamamoto, Tatsuo

Published
2009
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14. A New Local Variant (ST764) of the Globally Disseminated ST5 Lineage of Hospital-Associated Methicillin-Resistant Staphylococcus aureus (MRSA) Carrying the Virulence Determinants of Community-Associated MRSA

Author

Takano, Tomomi, primary, Hung, Wei-Chun, additional, Shibuya, Michiko, additional, Higuchi, Wataru, additional, Iwao, Yasuhisa, additional, Nishiyama, Akihito, additional, Reva, Ivan, additional, Khokhlova, Olga E., additional, Yabe, Shizuka, additional, Ozaki, Kyoko, additional, Takano, Misao, additional, and Yamamoto, Tatsuo, additional

Published
2013
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16. Novel Characteristics of Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains Belonging to Multilocus Sequence Type 59 in Taiwan

Author

Takano, Tomomi, primary, Higuchi, Wataru, additional, Zaraket, Hassan, additional, Otsuka, Taketo, additional, Baranovich, Tatiana, additional, Enany, Shymaa, additional, Saito, Kohei, additional, Isobe, Hirokazu, additional, Dohmae, Soshi, additional, Ozaki, Kyoko, additional, Takano, Misao, additional, Iwao, Yasuhisa, additional, Shibuya, Michiko, additional, Okubo, Takeshi, additional, Yabe, Shizuka, additional, Shi, Da, additional, Reva, Ivan, additional, Teng, Lee-Jene, additional, and Yamamoto, Tatsuo, additional

Published
2012
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17. Evolution and virulence of Panton-Valentine leukocidin-positive ST30 methicillin-resistant Staphylococcus aureus in the past 30 years in Japan

Author

Isobe, Hirokazu, primary, Takano, Tomomi, additional, Nishiyama, Akihito, additional, Hung, Wei-Chun, additional, Kuniyuki, Shuichi, additional, Shibuya, Yasuhiro, additional, Reva, Ivan, additional, Yabe, Shizuka, additional, Iwao, Yasuhisa, additional, Higuchi, Wataru, additional, Khokhlova, Olga E, additional, Okubo, Takeshi, additional, and Yamamoto, Tatsuo, additional

Published
2012
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19. Novel Characteristics of Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains Belonging to Multilocus Sequence Type 59 in Taiwan

Author

Takano, Tomomi, primary, Higuchi, Wataru, additional, Otsuka, Taketo, additional, Baranovich, Tatiana, additional, Enany, Shymaa, additional, Saito, Kohei, additional, Isobe, Hirokazu, additional, Dohmae, Soshi, additional, Ozaki, Kyoko, additional, Takano, Misao, additional, Iwao, Yasuhisa, additional, Shibuya, Michiko, additional, Okubo, Takeshi, additional, Yabe, Shizuka, additional, Shi, Da, additional, Reva, Ivan, additional, Teng, Lee-Jene, additional, and Yamamoto, Tatsuo, additional

Published
2008
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20. Multifocal pelvic abscesses and osteomyelitis from community-acquired methicillin-resistant Staphylococcus aureus in a 17-year-old basketball player

Author

Okubo, Takeshi, primary, Yabe, Shizuka, additional, Otsuka, Taketo, additional, Takizawa, Yoko, additional, Takano, Tomomi, additional, Dohmae, Soshi, additional, Higuchi, Wataru, additional, Tsukada, Hiroki, additional, Gejyo, Fumitake, additional, Uchiyama, Makoto, additional, and Yamamoto, Tatsuo, additional

Published
2008
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21. In vitro susceptibility to antimicrobial agents and ultrastructural characteristics related to swimming motility and drug action in Campylobacter jejuni and C. coli.

Author

Yabe, Shizuka, Higuchi, Wataru, Takano, Tomomi, Razvina, Olga, Iwao, Yasuhisa, Isobe, Hirokazu, and Yamamoto, Tatsuo

Subjects
CAMPYLOBACTER jejuni, CAMPYLOBACTER, FURAZOLIDONE, NITROFURANS, ANTI-infective agents
Abstract

Campylobacter jejuni has recently been noted as the most common cause of bacterial food-borne diseases in Japan. In this study, we examined in vitro susceptibility to 36 antimicrobial agents of 109 strains of C. jejuni and C. coli isolated from chickens and patients with enteritis or Guillain–Barré syndrome from 1996 to 2009. Among these agents, carbapenems (imipenem, meropenem, panipenem, and biapenem) showed the greatest activity [minimal inhibitory concentration (MIC)90, 0.03–0.125 μg/ml]. This was followed by sitafloxacin (MIC90, 0.25 μg/ml), furazolidone and azithromycin (MIC90, 0.5 μg/ml), gentamicin and clindamycin (MIC90, 1 μg/ml), and clavulanic acid (β-lactamase inhibitor; MIC90, 2 μg/ml). All or most strains were resistant to aztreonam, sulfamethoxazole, and trimethoprim. Marked resistance was also observed for levofloxacin and tetracyclines. Resistance was not present for macrolides and rare for clindamycin. C. jejuni (and C. coli) exhibited high swimming motility and possessed a unique end-side (cup-like) structure at both ends, in contrast to Helicobacter pylori and Vibrio cholerae O1 and O139. The morphology of C. jejuni (and C. coli) changed drastically after exposure to imipenem (coccoid formation), meropenem (bulking and slight elongation), and sitafloxacin (marked elongation), and exhibited reduced motility. In the HEp-2 cell adherence model, unusually elongated bacteria were also observed for sitafloxacin. The data suggest that although resistance to antimicrobial agents (e.g., levofloxacin) has continuously been noted, carbapenems, sitafloxacin, and others such as β-lactamase inhibitors alone showed good in vitro activity and that C. jejuni (and C. coli) demonstrated a unique ultrastructural nature related to high swimming motility and drug action. [ABSTRACT FROM AUTHOR]

Published
2010
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22. A New Local Variant (ST764) of the Globally Disseminated ST5 Lineage of Hospital-Associated Methicillin-Resistant Staphylococcus aureus(MRSA) Carrying the Virulence Determinants of Community-Associated MRSA

Author

Takano, Tomomi, Hung, Wei-Chun, Shibuya, Michiko, Higuchi, Wataru, Iwao, Yasuhisa, Nishiyama, Akihito, Reva, Ivan, Khokhlova, Olga E., Yabe, Shizuka, Ozaki, Kyoko, Takano, Misao, and Yamamoto, Tatsuo

Abstract

ABSTRACTThe ST5 lineage of methicillin-resistant Staphylococcus aureus(MRSA) is one of the most globally disseminated hospital-associated MRSA (HA-MRSA) lineages. We isolated a new local variant (designated ST764) over at least 5 years that causes invasive infections, including necrotizing fasciitis, and is carried by medical students, as well as household members. Analysis of the genome sequence of one isolate compared to that of the reference ST5 strain revealed that ST764 had acquired virulence traits similar to those of community-associated MRSA (CA-MRSA) through the acquisition of two new mobile genetic elements, ACMEII and SaPInn54, which carried ACME arcAand the staphylococcal enterotoxin B gene (seb), respectively, and through enhanced expression of cytolytic peptide genes, although ST764 was negative for Panton-Valentine leukocidin. Other differences between ST764 and ST5 included the acquisition of an ACMEII-related cassette (cJR1), prophage φ2NN54, and streptococcal Tn5251and decreased numbers of copies of Tn554. As for superantigen genes, although the two possessed seg, sei, sem, sen, and seo, ST764 lacked tst, sec, sel, and sep. The data suggest that ST764 MRSA is a novel hybrid variant of ST5 HA-MRSA with the characteristics of CA-MRSA and that the evolution of ST764 includes multiple steps, e.g., acquisition of novel or nonstaphylococcal mobile elements.

Published
2013
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23. Novel Characteristics of Community-Acquired Methicillin-Resistant Staphylococcus aureusStrains Belonging to Multilocus Sequence Type 59 in Taiwan

Author

Takano, Tomomi, Higuchi, Wataru, Otsuka, Taketo, Baranovich, Tatiana, Enany, Shymaa, Saito, Kohei, Isobe, Hirokazu, Dohmae, Soshi, Ozaki, Kyoko, Takano, Misao, Iwao, Yasuhisa, Shibuya, Michiko, Okubo, Takeshi, Yabe, Shizuka, Shi, Da, Reva, Ivan, Teng, Lee-Jene, and Yamamoto, Tatsuo

Abstract

ABSTRACTCommunity-acquired methicillin-resistant Staphylococcus aureus(CA-MRSA) strains, which often produce Panton-Valentine leucocidin (PVL), are increasingly noted worldwide. In this study, we examined 42 MRSA strains (25 PVL-positive [PVL+] strains and 17 PVL-negative [PVL−] strains) isolated in Taiwan for their molecular characteristics. The PVL+MRSA strains included CA-MRSA strains with multilocus sequence type (ST) 59 (major PVL+MRSA in Taiwan), its variants, and worldwide CA-MRSA ST30 strains. The PVL−MRSA strains included the pandemic Hungarian MRSA ST239 strain, the Hungarian MRSA ST239 variant, MRSA ST59 (largely hospital-acquired MRSA strains) and its variants, the pandemic New York/Japan MRSA ST5 strain (Japanese type), and the MRSA ST8 strain. The major PVL+CA-MRSA ST59 strain possessed a tetracycline resistance-conferring (tetKpositive) penicillinase plasmid and a drug resistance gene cluster (a possible composite transposon) for multidrug resistance. Moreover, it carried a novel staphylococcal cassette chromosome mec(SCCmec) with two distinct ccrCgenes (ccrC2-C8). This SCCmec(previously named SCCmectype VT) was tentatively designated SCCmectype VII. Sequencing of the PVL genes revealed the polymorphisms, and the PVL+CA-MRSA ST59 strain possessed the ST59-specific PVL gene sequence. The data suggest that a significant amount of clonal spread is occurring in Taiwan and that the major PVL+CA-MRSA ST59Taiwanstrain exhibits unique genetic characteristics, such as a novel SCCmectype and an ST59-specific PVL gene sequence.

Published
2008
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24. Novel Characteristics of Community-Acquired Methicillin-Resistant Staphylococcus aureusStrains Belonging to Multilocus Sequence Type 59 in Taiwan

Author

Takano, Tomomi, Higuchi, Wataru, Zaraket, Hassan, Otsuka, Taketo, Baranovich, Tatiana, Enany, Shymaa, Saito, Kohei, Isobe, Hirokazu, Dohmae, Soshi, Ozaki, Kyoko, Takano, Misao, Iwao, Yasuhisa, Shibuya, Michiko, Okubo, Takeshi, Yabe, Shizuka, Shi, Da, Reva, Ivan, Teng, Lee-Jene, and Yamamoto, Tatsuo

Published
2012
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