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Small and medium-sized enterprises (SMEs) play an indispensable role in China’s economy through making huge contributions to GDP, national employment, financial innovation and government taxation. However, SMEs in China have long faced financing constraints due to their inherent problems, such as financial information asymmetry, immature governance mechanisms, and lack of collateral under the traditional financial system, which have hindered their long-term development. In recent years, financial technology (Fintech) has entered a rapid development track, especially in China, providing new ideas and methods for solving the financing difficulties of SMEs from a technical perspective. In order to examine this, this paper measures the degree of financing constraints through the cash flow sensitivity of cash model and explores how the Fintech development affects financing constraints of SMEs in China and how this impact further communicated to the performance and the risks of SMEs by adopting two-way fixed effects models. The results show that Fintech could alleviate the financing constraints of SMEs. Furthermore, the mediating role of ownership is identified, presenting a better mitigating effect of Fintech on the financing constraints for private SMEs. In addition, both the performance and the risks of SMEs showed the upward single-sided U-shaped relationship with the increase of the Fintech development index, which indicates that Fintech could amplify performance while magnifying the risks of SMEs. The findings of this paper offer an important implication for China that regulatory authorities should consider and balance the financing constraint mitigation effect and risk amplification effect of Fintech.

Objective To summarize the clinical characteristics, treatment regimen and clinical outcomes of infantile hepatic hemangioma (IHH) with high-output heart failure (HHF). Methods A retrospective analysis was conducted on 3 IHH infants with concomitant HHF admitted to the Children's Hospital of Chongqing Medical University during October 2020 and October 2023. The characteristics, treatment plans and efficacy were analyzed in the 3 cases. CNKI, WANFANG DATA, Chinese Medical Association Journal Full-text Database, and PubMed databases were retrieved to search domestic and foreign literature concerning the diseases, and the enrolled cases were analyzed and reviewed. Results Among the 3 infants, they were 1 male and 2 females, and aged 1 d, 19 d and 80 d, respectively. The main clinical symptoms were dyspnea and respiratory distress. All 3 patients rapidly progressed to respiratory failure, pulmonary hypertension and heart failure after admission. Diffuse IHH was diagnosed in 2 cases and focal IHH in 1 case. One case of diffuse IHH underwent percutaneous hepatic artery embolization, and the cardiopulmonary function recovered on the day of surgery, and the ventilator was removed. In the other 2 cases, propranolol combined with steroid medication was used, and the estimated right ventricular systolic pressure and E wave to A wave mitral flow ratio (E/A) were the most sensitive indicators in echocardiographic monitoring. There were 24 cases included in literature review, with 4 cases of treatment failure and death, 3 cases of remission, and 17 cases of complete recovery. Conclusion Propranolol combined with steroid medication and percutaneous hepatic artery embolization are effective in treating IHH complicated with HHF. Right ventricular systolic pressure and E/A during drug therapy might be early sensitive marker for the early evaluation of potential therapeutic effects of drugs.

ObjectiveTo explore the influence of "Internet plus" postpartum health care service on postpartum depression, and to provide an evidence for reducing the incidence of postpartum depression and improving the quality of life for postnatal women.MethodsMothers who gave birth between August 1, 2021 and June 30, 2023 lived in the six streets of Xuhui District were selected as the research subjects. The puerperants were randomly divided into the intervention group and the control group according to the order of enrollment using a numerical numbering system, with 210 cases in each of the intervention group and control group. The intervention group adopted the "Internet plus" postpartum health care services, while the control group adopted the conventional postpartum health care services. The risk factors related to postpartum mental health and the incidence of postpartum depression were compared between the two groups.ResultsThere was no statistically significant difference in the scores of postpartum mental health-related risk factors between the two groups at the first 2 weeks and 1st month after delivery (t=0.736 and t=1.260, P>0.05). However, there was a statistically significant difference in the scores of postpartum mental health-related risk factors at the 3rd months after delivery and 6th months after delivery (t=2.089, P0.05). In the 1st month, the 3rd month and the 6th month after delivery, the intervention group adopted the "Internet plus" postpartum health care service, thus the differences in depression scores were statistically significant (t=2.616, t=2.793 and t=3.107, P

Abstract Background Recurrent aphthous stomatitis (RAS) is considered as the most common oral mucosal lesion affecting up to 25% of people worldwide. Thalidomide has been reported for the treatment of RAS, but the evidence has not been systematically evaluated. We first systematically reviewed the efficacy and safety of thalidomide for the treatment of RAS. Methods We searched The Cochrane Library, PubMed, Scopus, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), Chinese BioMedical Literature Database (CBM), Wanfang Data, and VIP information from inception to December 2023. Randomized controlled trials (RCTs) comparing thalidomide with control for RAS were included in the analysis. The primary outcome were complete response and overall response, and the secondary outcome were recurrence interval (RI), ulcer number and size, healing time, visual analogue scale (VAS), immunological data, and adverse events. Meta-analysis was conducted using the Review Manager 5.4 software. Results Twenty-one trials involving 1668 patients were included in this review. The results of our meta-analysis showed that thalidomide significantly improved the complete response rate and overall response rate, prolonged the recurrence interval, accelerated the healing process, reduced the number and size of ulcers, and lowered TNF-α levels in the treatment of RAS. However, thalidomide significantly increases adverse events. Results Thalidomide has a significant benefit in the treatment of RAS. However, considering the potential side effects of thalidomide, it may be an optimal treatment option for major RAS patients or cases that do not respond to topical agents. Trial registration PROSPERO registration number: CRD42024495038.

With high melting point, high hardness, high thermal conductivity, excellent electrical conductivity, and high temperature oxidation resistance, the TiB2 ceramic has been applied in the fields of aerospace, machinery manufacturing, metal smelting, electronic information, and so on. However, the high-end manufacturing application of TiB2 ceramic has been limited by the low relative density and the difficulty of machine-processing. The densification of TiB2 ceramic could be improved by doping modification, adding sintering additives, optimizing sintering process, and so on, which significantly improves the mechanical properties. The research progress of high-performance TiB2 ceramic in terms of composition design and sintering processing was reviewed in this paper. The applications of TiB2 ceramic were also prospected on precision tools, bulletproof armor, and cathode tools.

5G deterministic network is an important part to support the construction of 5G+ Industrial Internet, and it is of great significance to study the key technologies and landing schemes of 5G deterministic network. Firstly, 5G ultra-reliability low latency communication technology and frame replication and cancellation technology were studied to reduce transmission latency and improve reliability. Secondly, cyclic queue forwarding technology was explored in 5G networks to eliminate end-to-end jitter. Finally, a 5G deterministic network landing scheme was proposed and tested in actual industrial production labs. The test results show that the comprehensive performance of the proposed network scheme is better than the existing network schemes, and can meet the demand for 5G deterministic networks in many industrial scenarios.

Objective When turnouts are laid on slope, the longitudinal force increase on the track due to the cyclic braking of trains will cause uneven rail creeping phenomena， resulting in a more complex stress and deformation pattern for the turnout, and even affecting its normal service. Therefore, it is necessary to study the characteristics of stress and deformation of large-slope turnout rails under cyclic braking loads. Method Tests on fastener longitudinal resistance under CLA (cycling loads action) are conducted, and a non-linear finite element model of the No.9 turnout is established to analyze the turnout rail creeping pattern under CLA. Result & Conclusion The fastener system exhibits resistance degradation under CLA. The maximum creep of the turnout rail occurs after the first train braking. Under CLA, the cumulative increase in rail creeping gradually stabilizes with the increasing number of CLA. The presence of slope will significantly increase rail creeping amount under CLA. The train loading form has minimal influence on turnout rail creeping under cycling braking loads action.

C10H9CaN3O6, monoclinic, P21/n, a = 9.3441(2) Å, b = 6.6142(2) Å, c = 18.6509(4) Å, β = 92.001(2)°, V = 1151.99(5) Å3, Z = 4, R gt(F) = 0.0398, wR ref (F 2) = 0.1101, T = 298 K.

By confining light into a deep subwavelength scale to match the characteristic dimension of quantum emitters, plasmonic nanocavities can effectively imprint the light emission with unique properties in terms of intensity, directionality, as well as polarization. In this vein, achiral quantum emitters can generate chiral photons through coupling with plasmonic nanocavities with either intrinsic or extrinsic chirality. As an important metric for the chiral-photon purity, the degree of circular polarization (DCP) is usually tuned by various scattered factors such as the nanocavity design, the emitter type, and the coupling strategy. The physical mechanisms of the chiral photon generation, especially when plasmons and emitters step into the strong coupling regime, are less explored. In this paper, we extended the coupled-oscillator and Jaynes–Cummings models to their chiral fashion to account for the above factors within a single theoretical framework and investigated the chiroptical properties of a plasmonic nanocavity-emitter hybrid system from weak to strong coupling. It was demonstrated that both the circular differential scattering and prominent scattering DCP rely on the intrinsic chirality generated by breaking the mirror symmetry with the emitter, and is thereby tunable by the coupling strength. However, the luminescence DCP (as high as 87 %) is closely related to the extrinsic chirality of the bare nanocavity and independent of the coupling strength. The results thus reveal two different physical mechanisms of generating chiral photons in scattering and luminescence. Our findings provide a theoretical guideline for designing chiral photon devices and contribute to the understanding of chiral plasmon-emitter interaction.

To improve heat dissipation performance of panel-type radiator for transformer, this study investigated the flow and heat transfer characteristics of semi-detached inclined trapezoidal wing vortex generator (SDITW) in a closed channel on the air-side of the radiator. The SDITW was compared with the inclined delta wing (IDW) and inclined trapezoidal wing (ITW) channels. The effects of SDITW relative separation height (e 1/e 2), longitudinal pitch (p l), blockage ratio (e/(0.5H)), and inclination angle (α) were analyzed. First, compared with the IDW and ITW channels, the SDITW channel generates stable corner vortices and produces weaker transverse vortices and lower flow resistance due to the semi-detached structure of the wing. For Re = 5,125–15,375, the overall heat transfer performance (performance evaluation criteria; PEC) of the SDITW channel increases by 0.5–8.9 and 1.7–4.9% as compared with IDW and ITW channels, respectively. Furthermore, for the same e/(0.5H) and α, both the Nusselt number ratio and friction factor ratio of SDITW channel increase as e 1/e 2 and p l decrease. For p l = 70 mm, the SDITW channel exhibits a relatively better overall heat transfer performance. For the same e 1/e 2 and p l, the PEC of SDITW channel is maximum and the overall heat transfer performance is best when e/(0.5H) = 0.3 at Re = 10,250 and α = 30°–60°.

BackgroundDiabetic foot ulcer (DFU) is a severe complication that occurs in patients with diabetes and is a primary factor that necessitates amputation. Therefore, the occurrence and progression of DFU must be predicted at an early stage to improve patient prognosis and outcomes. In this regard, emerging evidence suggests that inflammation-related markers play a significant role in DFU. One such potential marker, the monocyte-lymphocyte ratio (MLR), has not been extensively studied in relation to DFU. This study aimed to define a connection between MLR and DFU.MethodsA cross-sectional study was conducted using National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2004. DFU was defined based on survey questionnaires assessing the presence of nonhealing ulcers in the lower extremities for more than 4 weeks in diabetes patients. The MLR was calculated as the ratio of the monocyte count to the lymphocyte count, which was directly obtained from laboratory data files. Logistic regression analysis was performed to assess the relationship between the MLR and DFU. Stratified analysis according to age, sex, body mass index, blood glucose, hemoglobin, and glycated hemoglobin categories was conducted, and multiple imputations were applied to missing data.ResultsIn total, 1246 participants were included; the prevalence of DFU was 9.4% (117/1246). A multivariable regression model revealed a significant association between DFU and a 0.1 unit increase in MLR after adjusting for all covariates (adjusted odds ratio=1.16, 95% confidence interval: 1.02-1.33). Subgroup analyses revealed consistent findings regarding the impact of MLR on the presence of DFU (p > 0.05).ConclusionMLR is significantly associated with DFU in diabetes patients, and can be used as one of the indicators for predicting the occurrence of DFU. MLR assessment may be a valuable component in the follow-up of patients with diabetes.

In the context of new power systems， the diverse distributed power sources and user-side behavior have introduced instability in bus loads， thus presenting a fresh challenge for short-term load forecasting. In response to this challenge， a noise reduction forecasting method for bus load based on sequence decomposition is proposed. The construction and decomposition rules of the variational mode decomposition （VMD） are applied to the sequence decomposition of bus load. The residual terms following the sequence decomposition are smoothed using locally weighted regression （LWR） to forecast the noise reduction of bus load. Based on the measured active power data of bus load in an area， a recurrent neural network （RNN） is constructed to forecast the bus load after noise reduction. The results indicate that this method effectively eliminates the noise of the bus load sequence， and the sequence tends to be smooth while retaining the characteristics of the original bus load sequence. Moreover， it yields excellent forecasting curves and accurate forecasting results.

We herein demonstrate a novel green mediated silver nanoparticles (AgNPs) using Pistacia atlantica bark aqueous extract for the treatment of gastric cancer under in vitro conditions. Physicochemical and structural features of the nanocomposite biomaterial were assessed by several techniques like UV-Vis spectrum, transmission electron spectroscopy, field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, and inductively coupled plasma-optical emission spectroscopy. The Ag NPs showed high antioxidant activities against 2,2-diphenyl-1-picrylhydrazyl (DPPH). The IC50 of Ag NPs and Butylated hydroxytoluene against DPPH were 132 and 77 µg/mL, respectively. In the oncological part of this research, the status of normal and gastric cancer AGS and KATO III cell lines was determined. The IC50 of AgNPs was 193 and 250 µg/mL against AGS and KATO III. It seems that the prepared NP have stopped the growth of gastric cancer cells and the recent cancer cells have been removed with high concentration of NPs.

The development of overhead lines has met the electricity demand of the rapidly developing society. However, the large-scale installation of overhead lines and the natural environmental differences in different regions increase the complexity of the real-time management of the lines. To improve the efficiency of line management, this article constructs a theoretical and simplified electromagnetic field model of 500 kV three-phase overhead lines and studies the method of monitoring the current-sag state of the lines based on analyzing the distribution of magnetic field intensity under the three-phase overhead lines. Moreover, the placement of the tunneling magnetoresistance (TMR) sensor array was analyzed, and the current and sag reconstruction algorithm of the line was further proposed. The calculation results show that the simplified magnetic field model is accurate in most areas under the overhead line. The comparison of condition number and sensor position sensitivity value on sensor placement evaluation shows that the sensor position sensitivity value is more comprehensive, and it is recommended to use dual-axis TMR magnetic sensors. The relative error of the line sag calculated by the proposed TMR sensor array and algorithm is less than 3% and 4% for balanced and unbalanced three-phase line currents, respectively.

The purpose of this study was to analyze the role of C-reactive protein/albumin ratio (CRP/ALB) in the diagnosis of complicated appendicitis in adults.

In this article, we consider a nonlocal problem with a strong singular term and a general weight function. By using Ekeland’s variational principle, we prove a necessary and sufficient condition for the existence of a positive solution. Moreover, a method of algebraic analysis is used to deal with the multiplicity of solutions. Compared with the existing literature, our problems and results are novel.

The gas flow distribution inside a blast furnace affects its smelting. Laser surface detection technology can control the gas flow distribution and promote the stable and smooth running of blast furnace by observing and adjusting the surface condition in the blast furnace in real-time. The laser surface inspection technology in blast furnace gas flow control and optimization was introduced, with Masteel 4,000 m3 blast furnace as an example. The results showed that the 30 W high-power laser had good penetration performance and could obtain clear scanning images of the material surface. In the process of strengthening smelting, the laser detection system determined that the central airflow of blast furnace was insufficient, resulting in a decrease in furnace condition stability, and promptly took measures to adjust the angle of the mineral coke fabric equipment and lifting line. After adjusting the material line, the central airflow was properly suppressed and stabilized, the angle of edge platform increased, the airflow developed properly, and two suitable gas flows were formed, which finally stabilized the furnace condition. Meanwhile, the small duct airflow other than the central airflow was found in time through the laser detection system, which provided conditions for operators to take measures to effectively eliminate the duct airflow, thereby avoiding big impacts on the blast furnace operation and technical and economic indexes. Therefore, the laser surface detection technology could effectively judge the gas flow distribution in the furnace, which contributed to timely adjustment of process parameters and optimization of blast furnace operation.

Media literacy education plays a vital role in college students’ ideological and political education in the new media era. The development and popularization of new media technology and the widespread use of the Internet and social media have significantly changed the way of acquiring, processing and disseminating information, and put forward new challenges and requirements for college students’ ideological and political education. In this context, an in-depth exploration of the effective way to integrate media literacy into college students’ ideological and political education can help enhance their media critical abilities and promote their overall development. This paper uses the three-dimensional media literacy curriculum model (visual culture, text analysis and individual competence) to design teaching strategies for integrating media literacy into civic and political education. Through a questionnaire survey of 2,000 college students and teachers, students’ media literacy scores increased from an average of 3.1159 to 3.4159 after applying the teaching strategy, with the most noticeable improvement in media awareness and comprehension, and Analysis and critical thinking. The study demonstrated a significant improvement in the ability of college students to analyze and evaluate online information by incorporating media literacy. Strengthening media literacy education, primarily through integrating the three-dimensional media literacy model of visual culture, text analysis and individual competence, can effectively enhance the media literacy of college students and provide necessary support for their healthy growth in the information society.

[Objective] The effects of winter irrigation on soil water-heat-salt migration and crop growth during the freezing-thawing period were analyzed in order to provide a scientific basis for controlling soil salinization, and to ensure food security. [Methods] Statistical analysis and visualization methods were used to compare and analyze soil water-heat-salt migration and crop growth in winter irrigation and non-winter irrigation areas based on meteorological, soil physicochemical indicators, and crop growth data in an experimental field in the Qingtongxia Irrigation District of Ningxia from 25 October 2018 to 3 October 2020. [Results] Soil temperature changes in the Qingtongxia Irrigation District lagged behind air temperature changes, and the shallow surface soil temperature was more significantly affected by air temperature changes. The soil gradually froze from the surface downward and the freezing depth deepened as the temperature decreased. The frozen layer of soil thawed simultaneously from the soil surface and the bottom of the measurement profile during the thawing period. The entire soil freezing and thawing period lasted for 98 days. The soil moisture content increased significantly after irrigation. During the freezing period, irrigation decreased the temperature of each soil layer by 0.1—1.1 ℃. The variation trends of soil temperature and moisture in different soil layers during the winter irrigation period were basically the same as those during the non-winter irrigation period. After winter irrigation, the salinity of each soil layer decreased, especially in the 0—30 cm soil layer, and salinity decreased significantly. However, after the freezing-thawing period, salt accumulated in the soil. Winter wheat grew taller and corn grew faster in the winter irrigation farmland than in the non-winter irrigation farmland. Average wheat and corn yields increased by 20.64% and 4.20%, respectively, in the winter irrigation farmland. [Conclusion] Winter irrigation affected the distribution of soil water, heat, and salt, and effectively reduced soil salinity, resulting in increased crop growth and yield (especially wheat yield) in the Qingtongxia Irrigation District.

UAVs （unmanned aerial vehicles） are now involved in intelligent transmission line inspection. Given the complex image backgrounds captured by UAVs and poor line inspection accuracy and low detection speed of UAVs， the paper proposes a power line inspection algorithm based on an improved SegNet model. Firstly， residual modules and asymmetric convolutions are introduced into the encoder to reduce the computational burden on the network. Secondly， the network layers of the decoding layer are reduced， and the features of the encoder and decoder are fused to improve inspection accuracy. Finally， the improved SegNet algorithm is used to train the power line dataset. The accuracy and mean intersection over union reach up to 89.4% and 86.62% respectively， and the single detection time is 46 ms. The experimental results show that the algorithm based on the improved SegNet model can achieve high-precision and real-time power line detection.

Optimization of direct-regulated wind power automatic generation control (AGC) system and grid online optimal dispatch system requires the establishment of an accurate wind farm available power estimation model. Based on the new energy stand-alone information management system, this paper put forward a method of accurate estimation of wind power plant considering power generation conditions and station losses. The Spearman correlation coefficient was used to determine the number of key historical moments in the estimation moment, and the theoretical power estimation model of wind turbines was established based on the long short-term memory (LSTM) network. The operating conditions of the wind turbines were subdivided into six types (named as waiting wind, power generation and outage etc.), and the equivalent circuit model of the loss in the wind farm was established. Finally, the actual data of a wind farm was used to perform simulation calculations. The calculation results show that the root mean square error is reduced by 40% when the theoretical power model of a single machine considers the historical wind speed;When the available power model of wind farm takes into account the power generation condition and in-station loss, the root square error is reduced by 76.9%. The available power estimation model for wind farms proposed in this paper will facilitate the optimization of online dispatching and direct-regulation wind power AGC system strategies, and improve the level of wind power consumption.

Objective： To establish a rapid qualitative and quantitative method for the adulteration of Camellia seed oil. Methods： The electronic nose technology combined with chemometrics was used to screen the difference variables based on one-way ANOVA. The qualitative model for identification of adulteration types of camellia seed oil was established through principal component analysis (PCA) and discriminant analysis (DA). A quantitative model for identifying the types and degrees of camellia seed oil adulteration was established using orthogonal partial least squares (OPLS). Results： The R2 of the model was over 0.98, the RMSEE was lower than 0.005, and the RMSECV was lower than 0.01, which had the high performance indicators. Through external verification, the qualitative identification rate of DA model for camellia seed oil samples of different adulteration types was as high as 100%, and OPLS model had good accuracy. Conclusion： The electronic nose technology combined with chemometrics could realize the rapid and nondestructive identification of camellia seed oil adulteration.

Aiming at the problems of high temperature and high humidity in coal mining facing, this paper studies the heat distribution law of coal mining facing, compares and analyzes the enthalpy difference method and Sigma thermal difference method to calculate the air supply volume. Based on this, mechanical cooling scheme is scientifically formulated, and the cooling effect is verified by numerical simulation method. The results show that: the air supply calculated by Sigma heat is more accurate than that by traditional enthalpy difference method, and the air supply is 22.4 kg/s, that is, 1 041.6 m3/min. It can be seen from the simulation results that the RWK350 air cooler can achieve effective cooling below the Coal Mine Safety Regulations at both the common 10 m and 15 m air duct outlet locations, thus achieving effective cooling of the driving roadway.

Laryngeal squamous cell carcinoma (LSCC) is an aggressive and lethal malignant neoplasm with extremely poor prognoses. Accumulating evidence has indicated that preferentially expressed antigen in melanoma (PRAME) is correlated with several kinds of cancers. However, there is little direct evidence to substantiate the biological function of PRAME in LSCC. The purpose of the current study is to explore the oncogenic role of PRAME in LSCC. PRAME expression was analyzed in 57 pairs of LSCC tumor tissue samples through quantitative real-time PCR, and the correlation between PRAME and clinicopathological features was analyzed. The result indicated that PRAME was overexpressed in the LSCC patients and correlated with the TNM staging and lymphatic metastasis. The biological functions and molecular mechanism of PRAME in LSCC progression were investigated through in vitro and in vivo assays. Functional studies confirmed that PRAME facilitated the proliferation, invasion, migration, and epithelial–mesenchymal transition of LSCC cells, and PRAME also promoted tumor growth in vivo. HDAC5 was identified as an upstream regulator that can affect the expression of PRAME. Moreover, PRAME played the role at least partially by activating PI3K/AKT/mTOR pathways. The above findings elucidate that PRAME may be a valuable oncogene target, contributing to the diagnosis and therapy of LSCC.

Abstract The doubly-fed induction generator (DFIG) with virtual inertia control and reactive damping control gives a renewable energy generation system inertia and damping characteristics similar to those of a thermal power plant, and the parameters of the control strategy have a direct impact on the small-signal stability of the system. This paper firstly introduces the operating characteristics and control strategies of DFIG-based damping control and virtual inertia control, establishes a small-signal model of the control-based DFIG integrated interconnected system, and investigates the effects of virtual inertia and reactive damping values on the small-signal stability of the system; then, the maximum damping ratio of the interval oscillation mode in small disturbance analysis is taken as the optimization objective, and the control parameters are the optimization variables. An optimization method of inertia and damping parameters is established for improving the small disturbance stability of the system. The results show that the optimization procedure could improve the damping ratio of the interval oscillation mode while ensuring the system frequency. The effects of virtual inertia and reactive damping values on the small signal stability of the system are investigated, and an optimal allocation model and method for virtual inertia used to improve the small disturbance stability of the system is proposed.

At present, the key links of coal mine gas control management still need manual supervision. The gas control measures can not achieve 'reliable quality' and 'process traceability'. The backward gas control management mode results in overlapping functions, poor process and low degree of data sharing. In view of the above problems, based on workflow technology, from the perspective of global management, the dynamic workflow construction method of coal mine gas control is studied. Firstly, the workflow, constraint conditions and implementation process of gas control in the minging face and coal uncovering working face are analyzed. The links of gas control flow is divided into two types: test and measure. It is specifically divided into five types of work, including approval of technical documents and reports, drilling construction, sampling, gas parameter measurement, and gas extraction and parameter detection. Secondly, the method reconstructs the last four types of work and further divides the work into 25 basic work units. The method uses Petri Nets to combine basic work units to establish different cross-departmental gas control complex business workflow. Based on the gas control workflow chart, a representation method for the implementation progress of gas control in the working face is established. The method uses the strategy of combining initiative and automation to assign task of the workflow. The method uses description files to dynamically generate and configure workflow networks to meet the requirements of dynamic workflow modeling for gas control. Finally, based on the Flowable workflow engine, the dynamic workflow function of gas control is developed and applied. The results show that the construction of dynamic workflow can make the gas control business process. It is conducive to improving the efficiency of gas control collaborative execution, realizing the rapid flow, tracking and sharing of data. It is conducive to monitoring the overall operation and optimization of gas control work, improving the decision-making capability of coal mine gas control, and innovating the management mode of coal mine gas control.

ObjectiveTo understand the occurrence of postpartum depression among puerperae in six communities in Xuhui District， Shanghai， and to analyze the related influencing factors of postpartum depression， so as to provide evidence for corresponding intervention measures.MethodsA total of 476 puerperae who gave birth from August 1， 2021 to February 28， 2022 in 6 communities in Xuhui District were selected as the survey subjects. They filled out a general situation questionnaire， Edinburgh Postpartum Depression Scale （EPDS） and a questionnaire on related influencing factors. Univariate and multivariate unconditional logistic regression analysis was conducted on the related influencing factors of postpartum depression.ResultsAccording to the EPDS score， 72 of the 476 puerperae in Xuhui District developed postpartum depression， and the incidence of postpartum depression was 15.13%. Multivariate unconditional logistic regression analysis showed that maternal introversion （OR=2.845， 95%CI：1.033‒7.842）， artificial feeding （OR=11.448，95%CI：2.438‒53.767）， postpartum insomnia （OR=2.559， 95%CI：1.244‒5.262）， lack of postpartum parenting experience （OR=2.324，95%CI：1.121‒4.820）， and family members caring about the gender of the child （OR=4.415， 95%CI：1.500‒12.994） were independent risk factors of postpartum depression， while the spouse being an only child （OR=0.434， 95%CI：0.224‒0.840） was a protective factor for postpartum depression.ConclusionPostpartum depression in Xuhui District is affected by many factors. Screening and intervention of high-risk groups should be strengthened to reduce the incidence of postpartum depression.

The role of the calcifying nanoparticles (CNPs) in the calcification process of the outer cyst wall in hepatic cystic echinococcosis (HCE) remains unknown. CNPs were isolated from the tissues of the patients with HCE. Western blotting, alkaline phosphatase staining, and alizarin staining were performed to detect the cellular calcium ion deposition induced by the CNPs. CCK-8 and flow cytometry assays were conducted to determine the effect of CNPs on the apoptosis of mesenchymal stem cells (MSCs). Western blot experiments were performed to examine the expression levels of apoptosis-related factors and TGF-β1/Smad signaling pathway constituents. Treatment with CNPs induced the differentiation of MSCs. Calcium-related proteins, including OPN, BMP-2, and RUNX2, were upregulated after the CNP treatment. Similarly, CNP exposure increased the cellular calcium ion deposition in MSCs. In addition, the expression of Bax and Caspase-8 was elevated by the CNPs in MSCs. Treatment with CNPs promoted MSC apoptosis and inhibited the MSC growth. The TGF-β1/Smad signaling pathway was also activated after the CNP treatment. This study indicated that CNPs may play a critical role in initiating calcification of the outer cyst wall of HCE and promote the decay of echinococcosis, providing a new strategy for the treatment of hepatic echinococcosis.

In the study of TAVR, 3-dimensional (3D) printed aortic root models and pulsatile simulators were used for simulation training and teaching before procedures. The study was carried out in the following three parts: (1) experts were selected and equally divided into the 3D-printed simulation group and the non-3D-printed simulation group to conduct four times of TAVR, respectively; (2) another 10 experts and 10 young proceduralists were selected to accomplish three times of TAVR simulations; (3) overall, all the doctors were organized to complete a specific questionnaire, to evaluate the training and teaching effect of 3D printed simulations. For the 3D-printed simulation group, six proceduralists had a less crossing-valve time (8.3 ± 2.1 min vs 11.8 ± 2.7 min, P < 0.001) and total operation time (102.7 ± 15.3 min vs 137.7 ± 15.4 min, P < 0.001). In addition, the results showed that the median crossing-valve time and the total time required were significantly reduced in both the expert group and the young proceduralist group (all P

At present, the mixing oil will be produced in the sequential transportation of various refined oil inescapable. The mixing oil is not qualified product which is needed to be dealt with. The Volume of mixing oil is less the better. How to reduce the volume of mixing oil in the transportation of product oil is the key to reduce the cost and improve pipeline efficiency. This paper discusses the cause and mechanism of mixed oil in refined products and the characteristics of mixed oil in mountain pipelines. Then, it is providing a calculation method of mixed oil quantity, and a detecting method of mixed oil section, and a treatment method after receiving mixed oil.

【Objective】 Bioretention is a method to purify water, and the aim of this paper is to study its effect on stormwater runoff. 【Method】 We took stormwater runoff in Shijiazhuang city as an example, investigating the outflow characteristics of the bioretention system in response to two rainfall patterns, constant pattern and Chicago pattern using column experiment and HYDRUS model. From the simulated results, we analyzed and discussed the sensitivities of the runoff to soil hydraulic parameters, catchment area and thickness of the planting soil layer. We also developed a model to predict the influence of rainfalls with different return periods (N) on outflow. 【Result】 Compared to constant rainfall, the Chicago rainfall pattern delayed the emergence of outlet-outflow and prolonged the ponding duration on the soil surface. The hydraulic parameters to which the runoff was sensitive include saturated soil permeability Ks, saturated soil water content θs, and the empirical parameter α in the van Genuchten formula. An increase in Ks increased the maximum outlet-drainage rate and brought forward its arrival time. Increasing θs prolonged the latent time and reduced the outflow rate and ponding duration. Increasing the parameter α resulted in an increase in outflow. Doubling the catchment area ratio increased the maximum drainage rate, the peak-reduction rate and ponding duration by 13%, 33% and 300%, respectively, whereas reducing the latent time by 16%. Change in thickness of the planting soil layer did not show a significant effect on the outflow pattern. 【Conclusion】 The bioretention system is more permeable with more than 90% of rainwater flowing through the planting soil layer. When the return period of the rainfall is no more than 5 years, there is no overflow with the peak reduction rate being 40.6%~76.5%, the latent time > 1 h and ponding time < 2 h.

Mitochondrial DNA (mt-DNA) is an important carrier of extranuclear genetic information. Recent research results show that mt-DNA is closely related to the occurrence and metastasis of various malignant tumors, and can be used for early diagnosis and targeted therapy of cancer. Therefore, further research on the mechanism of mt-DNA in digestive system malignant tumors has important clinical significance for screening and identifying tumor molecular markers for anti-tumor drug targets, cancer diagnosis and prognosis analysis. This article reviews the research progress on the potential relationship, clinical application and therapeutic targets of mt-DNA and digestive system malignancies.

Objective To evaluate the significance of sequential therapy concept in the treatment of humeral lateral condyle fracture combined with elbow dislocation in children. Methods A retrospective analysis was performed on the clinical data of 16 children with humeral lateral condyle fracture combined with elbow dislocation who were treated in our hospital under the concept of sequential therapy from January 2010 to December 2020. The conditions of different Jakob classification before and after reduction were observed, the lateral condylar prominence index (LCPI) and the distal humeral intercondylar width (IEW) before and after surgery were measured, and the excellent and good rate of Flynn's elbow score and complications were assessed. Results All cases were followed up for an average of 27.5 (12~37) months. There was no significant difference in Jakob typesⅠandⅡbefore and after reduction, while in Jakob type Ⅲ, statistical difference was observed (P < 0.05). In addition, the pre- and post-operative LCPI and IEW had no significant difference. At the last follow-up, according to Flynn's elbow scale, 9 cases attained excellent therapeutic efficacy, 6 good, and 1 fair, with an excellent and good rate of 93.8%. Conclusion The treatment plan based on the concept of sequential therapy has a proved therapeutic effect in the treatment of children with humeral lateral condyle fracture combined with elbow dislocation, especially for fracture of Jakob type Ⅲ, which is worth clinical promotion.

The establishment of nature reserves is an important measure to protect rare wild animals and plants and their habitats. This plays a positive role in alleviating the ill effects of change in land use and protecting ecological diversity. Since the establishment of the first nature reserve in China, there has been notable development in the construction and infrastructure industry. Owing to this development, understanding whether nature reserves can effectively achieve the purpose of protection has gradually become a hot topic. An in-depth understanding of the evolution of land use types in nature reserves and their adjacent areas can evaluate the effectiveness of the construction of nature reserves, provide decision support for land resource planning, and help maintaining the balance of the ecosystem and sustainable development. Understanding the spatio-temporal evolution pattern of land use is important to create and preserve ecological security in protected areas. In this research, we studied the land use dynamics in Guangxi Golden Camellia national nature reserve and its adjacent two-kilometer buffer zone. Land use information was extracted from seven Landsat TM/OLI images from 1986, 1994, 1999, 2004, 2009, 2014, and 2019. The spatio-temporal dynamics of land use over the past 35 years were studied using decision tree analysis and a transition matrix. The results showed that the land use in the reserve is mainly dominated by forestland, and the adjacent areas of the reserve is mainly dominated by forestland and arable land. Although the proportion of construction land is small, it has increased annually over the past 35 years. It was observed from the studies that the dynamic degree of construction land was always relatively high in the non-core region of the reserve and the adjacent areas, whereas the dynamic degrees of other land types fluctuated more gently, and the integrated land use dynamic degree of the adjacent areas was less. The core area changed more drastically, the change in the trend of the comprehensive land use dynamic degree in the adjacent areas and the non-core area was similar. After the establishment of the reserve, human disturbance was reduced in this region, and the land-use pattern became more stable. Furthermore, the conversion of land use types in the adjacent areas was frequent, of which the transfer and exchange between cultivated land and forest land was the most drastic, the conversion of land use in the non-core region was less. This shows that the establishment and management of the reserve effectively protects the local ecological environment. Additionally, the studies showed that the migration of the land use center of gravity had a certain direction. The center of gravity of all land use types in the non-core area of the reserve generally migrated to the northeast, and the center of gravity of construction land and cultivated land in the adjacent area of the reserve generally migrated to the west, indicating that the expansion of the original construction land had a strong influence on land use dynamics. The management of the reserve has achieved relatively remarkable effects and the ecological environment inside the reserve has been improved, but the slow increase of land for internal construction and resources exploitation still have a negative impact on the habitat quality of the reserve. This study provides data to support the dynamic monitoring of land use and further improvement of protection and restoration measures in subtropical natural reserves.

ObjectiveTo explore the impact of primiparas’ intention to have a second child on their delivery mode.MethodsDuring March 1st， 2019 and November 30th， 2020， the enrolled pregnant women were investigated by questionnaires at two points， first trimester pregnancy registration and post-natal visit at maternal and child healthcare community centers of Xuhui District. Logistic regression analysis was used to examine the association of willingness of a second birth and their mode of delivery.Results2 000 questionnaires were distributed and 1 664 valid questionnaires were analyzed. The overall cesarean delivery rate in nulliparous women was 40.08% （667/1 664）， with 8.95% （149/1 664） of non-medical indication cesarean delivery. Multiple Logistic regression analysis of overall delivery rate showed that age， willingness to have more children in the future， plan of vaginal delivery at first questionnaire， and complications during pregnancy were associated with overall cesarean delivery rate， and women without the willingness to have more children in the future were more likely to undergo cesarean delivery （OR=1.350， 95%CI： 1.052-1.732）. Age， whether to have a second child in the future， plan of vaginal delivery at first questionnaire， and complications during pregnancy were all factors associated with increased risks of non-medical indicated cesarean delivery， while women with no plan of a second child in the future had nearly 2 times of risk of non-medical indicated cesarean delivery （OR=1.909， 95%CI： 1.117-3.262）.ConclusionThe mode of delivery is affected by many factors， among which willingness to have more children in the future is an important factor associated with increased risks of overall cesarean delivery and non-medical indicated cesarean delivery.

In order to solve the problem of seasonal pit water surplus and water shortage in Baorixile Open-pit Mine and realize the reasonable storage and utilization of water resources in the mine area, based on the study of geological, hydrogeological and structural conditions of the mine area, the water quality characteristics of the mine and the treatment of typical pollution components were studied. The results show that Baorixile Mining Area was located in the complete Chenqi Coalfield hydrogeological unit, it was a wavy high plain landform, and the Quaternary floor was higher than the regional groundwater level, which belongs to the permeable and non-water bearing stratum; the hydraulic connection between the aquifers of the Cretaceous Damoguaihe Formation was not obvious, and the coal seam was the main water bearing medium. Controlled by the geological structure and paleogeographic environment, the east, south and north sides of Baorixile Mining Area are water separation boundaries, and the west was recharge boundary, forming a relatively closed syncline water storage structure. The east side of the first mining area is an anticline axis, and a NNW normal fault (F15) is developed. Due to the interlacing of aquifers, a natural dam with good water resisting performance (dam width > 200 m) is formed between the first mining area and the second mining area. The construction of underground reservoir in the west side of the first mining area can not only ensure the safety of dump and mining pit in the second mining area, but also realize the effective water storage in the west side of the first mining area, and the water storage capacity can be increased 119.0 × 104 m3. There is a great seasonal difference in water use in the mining area. The surplus of mine water in winter and spring is 72×104 to 81×104 m3. The turbidity of Baorixile Mine water can be reduced to the limit of water quality standard by coagulation and precipitation pretreatment and surface soil strengthening treatment, which can realize the quantity and quality safety of underground storage of mine water. The effective protection and sustainable utilization of mine water in Baorixile Mining Area are realized by determining safe underground water storage location and developing scientific and reasonable pretreatment process.