37 results on '"Y. S. Chun"'
Search Results
2. The outcome of cementless total hip arthroplasty in haemophilic hip arthropathy
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Alankar Ramteke, Y. S. Chun, Y. J. Cho, Myung Chul Yoo, and Kang-Il Kim
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Adult ,Male ,musculoskeletal diseases ,medicine.medical_specialty ,Osteolysis ,Arthroplasty, Replacement, Hip ,medicine.medical_treatment ,Hemorrhage ,Hemophilia A ,Haemophilia ,Young Adult ,Arthropathy ,medicine ,Humans ,Young adult ,Genetics (clinical) ,Retrospective Studies ,Fixation (histology) ,Hemostasis ,business.industry ,Retrospective cohort study ,Hematology ,General Medicine ,Middle Aged ,musculoskeletal system ,equipment and supplies ,medicine.disease ,Arthroplasty ,Surgery ,Radiography ,Treatment Outcome ,surgical procedures, operative ,Harris Hip Score ,Hip Joint ,business - Abstract
Total hip arthroplasty (THA) in haemophilic arthropathy is reported to be less successful than in non-haemophilic indications. Although preliminary results are encouraging, the survival and functional outcome of cementless THA in haemophilia are not known. The aim of this study was to analyse mid-term results of cementless THA in haemophilia. Twenty-seven consecutive cementless THAs with 23 patients performed between June 1995 and June 2003 were reviewed. Mean age at time of operation was 36 years and mean follow-up period was 92 months (range, 60-156). Radiographic assessment was done for fixation of components, loosening, osteolysis, wear and bone responses around the implants. The factor requirements, amount of transfusion and complications associated with bleeding were studied. The mean preoperative Harris hip score changed from 57 to 95.9 at the latest follow-up. The survival at mean follow-up was 95.2%. One patient with osteolysis around acetabular cup was re-operated with bone-grafting and change of polyethylene liner. One loose cup was revised with a cemented cup. All other components were deemed stable at the latest follow-up. A standardized management protocol and dedicated team approach comprising of haematologist, physicians, physical therapist, nurses and coordinators is needed for excellent results. The present retrospective study shows that the functional results of cementless THA in haemophilia are satisfactory as it happens in osteoarthritic patients according to the current literature, mainly the younger. Thus, taking into account that the majority of haemophilia patients requiring a THA are relatively young, cementless THA is currently recommended.
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- 2009
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3. The interdental gingiva, a visible guide for placement of mini-implants
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U. M E Wikesjö, S. K. Lee, Y. S. Chun, and Woo Hyeon Lim
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Adult ,Male ,Molar ,Gingiva ,Dentistry ,Orthodontics ,Young Adult ,stomatognathic system ,Alveolar Process ,Orthodontic Anchorage Procedures ,Premolar ,Humans ,Medicine ,Maxillary central incisor ,Dental Implants ,Miniaturization ,business.industry ,Alveolar process ,Dental Implantation, Endosseous ,Mandible ,Interdental consonant ,stomatognathic diseases ,medicine.anatomical_structure ,Otorhinolaryngology ,Maxilla ,Calipers ,Female ,Surgery ,Oral Surgery ,Tomography, X-Ray Computed ,business - Abstract
Structured Abstract Authors – Chun YS, Lee SK, Wikesjo UME, Lim WH Objectives – To determine whether the tip of the interdental gingiva can serve as a visible guide for placement of mini-implants. Setting and Sample population – Computer tomography (CT) images from 15 males and 15 females (mean age 27 years, range: 23–35 years) were used to evaluate the distance from the tip of the interdental gingiva to the alveolar crest from the central incisor to the 1st molar. The distance from a reference point to the tip of interdental gingiva was recorded from study models using a caliper. The distance between the reference point and the alveolar crest was recorded using CT and added to the model recordings thus providing the distance from the tip of interdental gingiva to the alveolar crest for the various interdental sites. Two-way anova and Student–Newman–Keuls test for multiple comparisons were used for the statistical analysis. Results – There was no significant difference in the distance from the tip of interdental gingiva to the alveolar crest between maxilla and mandible. The distance between the tip of interdental gingiva and the alveolar crest at the central/lateral incisors was the shortest compared with that of other sites. There was also a statistically significant difference between the male and female groups except for the maxillary 2nd premolar/1st molar interradicular site. Conclusion – The tip of interdental gingiva appears a reasonable visual guide for the placement of mini-implants for orthodontic anchorage.
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- 2009
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4. Nanomagnetism and spin electronics: materials, microstructure and novel properties
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P. Blomqvist, B. K. Roberts, A. B. Pakhomov, Marcela Gonzales, Yuping Bao, Y. S. Chun, Kelli A. Griffin, Kannan M. Krishnan, and Xiaosong Ji
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Exchange bias ,Materials science ,Spintronics ,Mechanics of Materials ,Mechanical Engineering ,Magnetic nanoparticles ,Nanoparticle ,General Materials Science ,Nanotechnology ,Heterojunction ,Electronics ,Thin film ,Microstructure - Abstract
We present an overview of the critical issues of current interest in magnetic and magnetoelectronic materials. A broad demonstration of the successful blend of materials synthesis, microstructural evolution and control, new physics and novel applications that is central to research in this field is presented. The critical role of size, especially at the nanometer length scale, dimensionality, as it pertains to thin films and interfaces, and the overall microstructure, in determining a range of fundamental properties and potential applications, is emphasized. Even though the article is broad in scope, examples are drawn mainly from our recent work in magnetic nanoparticles and core-shell structures, exchange, proximity and interface effects in thin film heterostructures, and dilute magnetic dielectrics, a new class of materials for spin electronics applications.
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- 2006
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5. Cementless total hip arthroplasty for haemophilic arthropathy: follow-up result of more than 10 years
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Y. S. Chun, K. H. Rhyu, Y. J. Cho, Myung Chul Yoo, and S. H. Lee
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musculoskeletal diseases ,Adult ,Male ,medicine.medical_specialty ,Osteolysis ,Arthroplasty, Replacement, Hip ,Haemophilia ,Hemophilia A ,Young Adult ,Arthropathy ,Medicine ,Humans ,Genetics (clinical) ,Flexion contracture ,Clotting factor ,business.industry ,Hematology ,General Medicine ,Perioperative ,Middle Aged ,medicine.disease ,Surgery ,Harris Hip Score ,Quality of Life ,business ,Range of motion ,Follow-Up Studies - Abstract
The improvement of prophylaxis and adequate replacement of clotting factors, the quality of life and natural history of haemophilia have been significantly improved. However, significant functional impairment is inevitable. This study was performed to evaluate over 10 years clinical and radiographic outcomes of cementless total hip arthroplasty (THA) for treatment of haemophilic hip arthropathy. Between 1995 and 2003, 27 cases of cementless total hip arthroplasties were performed in 23 haemophilic patients. A total of 21 cases from 17 patients were available for follow-up analysis over 10 years. Modified Harris hip score, the range of motion of the hip joint, perioperative coagulation factor requirements and complications associated with bleeding were evaluated as part of the clinical assessment. For the radiographic assessment, fixation of component, osteolysis, loosening and other complications were evaluated. Clinically, the mean Harris hip score improved from 57 points before the operation to 94 points at the last follow-up. The mean flexion contracture was 10° preoperatively and 0.9° at the final follow-up. The further flexion improved from 68.4° to 90.5° after surgery. The mean monthly requirement of factor VIII reduced from 3150 units before surgery to 1800 units at the time of the last follow-up. There were three cases of rebleeding. In one case, a progressive haemophilic pseudotumour was found. Reoperation for any reason including revision was performed in three cases. We believe that cementless THA in patient with haemophilic hip arthropathy can bring reliable pain relief and functional improvement for longer than 10 years.
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- 2014
6. Neuromuscular interaction between cisatracurium and mivacurium, atracurium, vecuronium or rocuronium administered in combination
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J. K. Suh, K. S. Kim, Y. S. Chun, and S. U. Chon
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Adult ,Male ,Neuromuscular Junction ,Anesthesia, General ,Mivacurium chloride ,medicine ,Atracurium besilate ,Humans ,Drug Interactions ,Androstanols ,Rocuronium ,Rocuronium Bromide ,Vecuronium Bromide ,Besilate de cisatracurium ,Dose-Response Relationship, Drug ,Adult patients ,business.industry ,Drug Synergism ,Middle Aged ,Isoquinolines ,Mivacurium ,Anesthesiology and Pain Medicine ,Cisatracurium besilate ,Anesthesia ,Atracurium ,Female ,Neuromuscular Blocking Agents ,Vecuronium bromide ,business ,Neuromuscular Nondepolarizing Agents ,medicine.drug - Abstract
We compared the dose-response relationships of cisatracurium, mivacurium, atracurium, vecuronium and rocuronium and examined the interactions of cisatracurium with mivacurium, atracurium, vecuronium and rocuronium in humans by isobolographic and fractional analyses. We studied 180 adult patients during nitrous oxide-fentanyl-propofol anaesthesia. Neuromuscular block was monitored using mechanomyography to detect the twitch response of the ulnar nerve at the wrist. The dose-response curves were determined by probit analysis. The calculated ED50 values and their 95% confidence intervals were 40.9 (38.1-43.7), 49.8 (47.0-52.6), 187.2 (175.1-199.3), 36.6 (34.7-38.5) and 136.4 (129.2-143.6) micrograms.kg-1 for cisatracurium, mivacurium, atracurium, vecuronium and rocuronium, respectively. Corresponding ED95 values were 57.6 (53.5-61.7), 91.8 (88.1-95.5), 253.1 (238.9-267.3), 52.9 (49.1-56.7) and 288.7 (276.2-301.2) micrograms.kg-1, respectively. The interaction between cisatracurium and mivacurium, vecuronium or rocuronium was found to be synergistic, but the interaction between cisatracurium and atracurium was found to be additive. Synergy between cisatracurium and vecuronium or rocuronium was greater than between cisatracurium and mivacurium.
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- 1998
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7. Characterization of unicompositional GaInP2 ordering heterostructures grown by variation of V/III ratio
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Tae Yeon Seong, C. E. Inglefield, I. H. Ho, P. C. Taylor, Junghwan Kim, Gerald B. Stringfellow, M. C. DeLong, and Y. S. Chun
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Materials science ,Photoluminescence ,business.industry ,Band gap ,General Physics and Astronomy ,Heterojunction ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Epitaxy ,Molecular physics ,Spectral line ,Condensed Matter::Materials Science ,Excited state ,Optoelectronics ,Photoluminescence excitation ,Absorption (electromagnetic radiation) ,business - Abstract
Photoluminescence (PL) and photoluminescence excitation (PLE) spectroscopies are employed to investigate single heterostructures based on two GaInP2 layers that have the same composition but different degrees of order on the cation sublattice. Four sample configurations are studied: two complementary single heterostructures, a more ordered layer grown on a less ordered layer and vice versa, and two single layers nominally equivalent to the constituent layers of the heterostructures. The degree of order of the two layers was controlled via the V/III ratio used during organometallic vapor phase epitaxial growth. From our measurements, the difference between the band gaps of the two layers is 20–30 meV. The PLE spectra show clearly that the emission comes from both layers of the heterostructures and that the PL is excited by direct absorption of the exciting light into each layer as well as the injection of carriers from the less ordered (higher band gap) layer into the more ordered (lower band gap) layer. T...
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- 1997
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8. Growth of order/disorder heterostructures in GaInP using a variation in V/III ratio
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Joon Hyung Kim, Tae Yeon Seong, I. H. Ho, Y. Hsu, Gerald B. Stringfellow, T. C. Hsu, H. Murata, and Y. S. Chun
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Materials science ,Photoluminescence ,Band gap ,Superlattice ,Analytical chemistry ,Heterojunction ,Partial pressure ,Condensed Matter Physics ,Epitaxy ,Electronic, Optical and Magnetic Materials ,Crystallography ,Monolayer ,Materials Chemistry ,Electrical and Electronic Engineering ,Surface reconstruction - Abstract
CuPt ordering, resulting in formation of a natural monolayer {111} superlattice, occurs spontaneously during organometallic vapor phase epitaxial growth of Ga0.52In0.48P. The degree of order is found to be a function of the input partial pressure of the phosphorus precursor (PP) during growth. This is thought to be mainly due to the effect of PP on the surface reconstruction. A change in order parameter is associated with a change in the bandgap energy. Thus, a practical application of ordering is the production of a heterostructure by simply changing the flow rate of the P precursor during growth. Examination of transmission electron microscopy data and photoluminescence spectra indicates that order/disorder (O/D) (really less ordered on more ordered) and D/O heterostructures formed by growth using PH3 at a temperature of 620°C are graded over several thousands of A: The ordered structure from the lower layer persists into the upper layer. Similar results were obtained at 620°C when the first layer was grown using PH3 (V/III=160) and the second using tertiarybutylphosphine (TBP) (V/III=5). The use of a temperature of 670°C to produce heterostructures using either PH3 or TBP yields a totally different behavior. Abrupt D/O and O/D heterostructures can be produced by changing PP during the growth cycle. The cause of this difference in behavior is not entirely clear. However, it appears to be related to a very slow change in the surface reconstruction, measured using surface photo absorption, when the PH3 partial pressure is changed at 620°C.
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- 1997
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9. Heterostructures in GaInP grown using a change in V/III ratio
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S. H. Lee, Tae Yeon Seong, C. E. Inglefield, Junghwan Kim, I. H. Ho, H. Murata, T. C. Hsu, Gerald B. Stringfellow, M. C. DeLong, Y. S. Chun, and P. C. Taylor
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Crystallography ,Materials science ,Photoluminescence ,Transmission electron microscopy ,law ,Superlattice ,Monolayer ,General Physics and Astronomy ,Heterojunction ,Partial pressure ,Electron microscope ,Epitaxy ,law.invention - Abstract
A natural monolayer {111} superlattice (the CuPt ordered structure) is formed spontaneously during organometallic vapor phase epitaxial (OMVPE) growth of Ga0.52In0.48P. The extent of this ordering process is found to be a strong function of the input partial pressure of the phosphorus precursor during growth due to the effect of this parameter on the surface reconstruction and step structure. Thus, heterostructures can be produced by simply changing the flow rate of the P precursor during growth. It is found, by examination of transmission electron microscope (TEM) and atomic force microscope (AFM) images, and the photoluminescence (PL) and PL excitation (PLE) spectra, that order/disorder (O/D) (really less ordered on more ordered) heterostructures formed by decreasing the partial pressure of the P precursor during the OMVPE growth cycle at a temperature of 620 °C are graded over several thousands of A when PH3 is the precursor. The ordered structure from the lower layer persists into the upper layer. Sim...
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- 1997
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10. Co-pyrolysjs of DIPSbH and TMIn
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Y. S. Chun, R. W. Gedridge, and Gerald B. Stringfellow
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Alkane ,chemistry.chemical_classification ,Reaction mechanism ,Inorganic chemistry ,Disproportionation ,Condensed Matter Physics ,Rate-determining step ,Dissociation (chemistry) ,Electronic, Optical and Magnetic Materials ,Elimination reaction ,chemistry.chemical_compound ,chemistry ,Materials Chemistry ,Electrical and Electronic Engineering ,Trimethylindium ,Pyrolysis - Abstract
The reaction mechanisms for the pyrolysis of diisopropylantimonyhydride (DIPSbH, (C3H7)2SbH) alone and for the co-pyrolysis of DIPSbH and trimethylindium (TMIn, (CH3)3In) in D2 and H2 ambients have been studied in an isothermal flow-tube, “ersatz” reactor using mass spectrometry to analyze the reaction products. The rate limiting step in the pyrolysis of DIPSbH alone is the reductive coupling reaction, producing C3H8. Additional products are C3H6 and C6H14produced by disproportionation and recombination reactions, respectively, of C3H7 radicals produced during the second stage of DIPSbH pyrolysis. The mixture of DIPSbH with TMIn produces a nonvolatile adduct on the quartz walls immediately after mixing in the reactor even at room temperature. No products were evolved at room temperature. However, for reactor temperatures between 100 and 200°C, an alkane elimination reaction occurs, producing CH4. The remaining solid product is postulated to be [(CH3)2InSb(C3H7)2]n (n = 2 or 3). For temperatures greater than 200°C, the DIPSbH begins to pyrolyze independently. This temperature for the onset of DIPSbH pyrolysis is considerably above the temperature (125°C) at which pyrolysis begins for DIPSbH alone. This suggests that during co-pyrolysis formation of the adduct retards pyrolysis of DIPSbH. Apparently, dissociation of the adduct is necessary before the DIPSbH can pyrolyze independently. Co-pyrolysis of DIPSbH and TMIn between 250 and 375°C produces (C3H7)Sb(CH3)2 and (CH3)3Sb. Neither is found for the pyrolysis of DIPSbH alone. Considerably larger amounts of C2H6 are also detected at low temperatures (≤ 300°C). The ethane may come from the [(CH3)2InSb(C3H7)2]n via an intramolecular alkane elimination reaction. The high carbon contamination levels reported for InSb samples grown by OMVPE using these precursors at 300 and 325°C are postulated to be caused by the formation of (C3H7)Sb(CH3)2 during the co-pyrolysis of DIPSbH and TMIn, but not during the pyrolysis of each precursor alone.
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- 1996
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11. Effects of V/III ratio on ordering in GaInP: Atomic scale mechanisms
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I. H. Ho, Y. S. Chun, H. Murata, Y. Hosokawa, Gerald B. Stringfellow, L. C. Su, and T. C. Hsu
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chemistry.chemical_compound ,Photoluminescence ,chemistry ,Electron diffraction ,Phosphorus ,Torr ,Analytical chemistry ,General Physics and Astronomy ,chemistry.chemical_element ,Partial pressure ,Epitaxy ,Spectroscopy ,Phosphine - Abstract
Ga0.5In0.5P layers have been grown by organometallic vapor‐phase epitaxy using various values of input V/III ratio for two phosphorus precursors, phosphine, the conventional precursor, and tertiarybutylphosphine (TBP), a newly developed, less‐hazardous precursor. For growth on nominally (001) GaAs substrates misoriented by 3° (and in some cases by 0° or 6°) to produce [110] steps on the surface at a growth temperature of 620 °C, the Cu–Pt‐type ordering is found to be strongly affected by the input flow rate of the phosphorus precursor (V/III ratio). For decreasing input partial pressures below 3 Torr for PH3 and 0.75 Torr for TBP the low‐temperature photoluminescence (PL) peak energy increases indicating a lower degree of order. This is confirmed by transmission electron diffraction results. The decrease in the degree of order corresponds to a decrease in the concentration of [110]‐oriented P dimers on the surface, as indicated by surface photoabsorption spectroscopy results. These data indicate that the...
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- 1996
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12. Interlayer perpendicular domain coupling between thin Fe films and garnet single-crystal underlayers
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Y. S. Chun and Kannan M. Krishnan
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Materials science ,Magnetic structure ,Condensed matter physics ,Magnetic domain ,Sputtering ,General Physics and Astronomy ,Magnetic force microscope ,Sputter deposition ,Thin film ,Magnetic hysteresis ,Single crystal - Abstract
The magnetic behavior and domain structure of Fe films grown on yttrium–iron–garnet (YIG) underlayers were studied to elucidate their interlayer coupling, as a function of the Fe layer thickness, using magnetic force microscopy (MFM) and magneto-optic Kerr effect (MOKE). The YIG layer, grown by liquid phase epitaxy on single crystal gadolinium–gallium–garnet (GGG) substrates, showed a characteristic stripe domain structure in MFM images. Fe layers with thickness values of (5, 10, and 20 nm) were separately deposited on the YIG layer using ion beam sputtering system at room temperature. MOKE measurements of Fe/YIG/GGG with different Fe thickness showed that Fe films preferred to be magnetized perpendicular to the surface when the thickness was less than 20 nm. Stripe domain structure was observed for Fe thickness of 5 and 10 nm, but not for 20 nm film. Micromagnetic simulations of these Fe/YIG bilayers show that the volume exchange stiffness term at the interface plays a dominant role, when compared with t...
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- 2004
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13. Effect of growth rate on step structure and ordering in GaInP
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S. H. Lee, I. H. Ho, Y. S. Chun, and Gerald B. Stringfellow
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Crystallography ,Materials science ,Condensed matter physics ,Misorientation ,Atomic force microscopy ,Lattice (order) ,Monolayer ,General Physics and Astronomy ,Growth rate ,Epitaxy ,Vicinal ,Surface reconstruction - Abstract
Ga0.5In0.5P layers grown by organometallic vapor‐phase epitaxy on GaAs substrates misoriented by angles of 3°, 6°, and 9° from (001) toward the [110] direction in the lattice have been studied using atomic force microscopy. The [110] steps are found to bunch in places to produce supersteps ranging in height from a few monolayers to as large as 30–70 A. The supersteps, consisting of a (11n) facet adjacent to an (001) facet, are separated by an apparently vicinal surface. Both the height of the largest supersteps and the value of n depend on the growth conditions. The (001) facet length depends only slightly on misorientation angle and declines as (growth rate)−1/2, consistent with a diffusion limitation of the facet size. The distance between supersteps increases rapidly with decreasing growth rate and increasing substrate misorientation. A comparison of the superstep spacing and the distance between antiphase boundaries in the Cu–Pt‐ordered structure formed during growth indicates a one‐to‐one correspondence. This leads to the hypothesis that the supersteps lead to loss of phase in the ordered structure during growth.
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- 1995
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14. Lipoblastoma
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Y S, Chun, W K, Kim, K W, Park, S C, Lee, and S E, Jung
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Male ,Rectal Neoplasms ,Infant ,Soft Tissue Neoplasms ,General Medicine ,Treatment Outcome ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Humans ,Female ,Surgery ,Lipoma ,Retroperitoneal Neoplasms ,Retrospective Studies - Abstract
Lipoblastoma is a rare benign mesenchymal tumor of embryonal fat that occurs almost exclusively in infants and children. This study was done to determine the clinical and pathologic characteristics of lipoblastoma.Nine cases of pathologically proven lipoblastoma from 1979 to 1997 were reviewed. There were 6 boys and 3 girls ranging in age from 3 months to 29 months.A soft tissue mass was the chief complaint in 7 patients, abdominal distension in 1 patient with a retroperitoneal mass, and defecation difficulty in 1 patient with a perirectal mass. In 4 patients, tumors occurred on the back. Other tumor location includes the neck, scrotum, retroperitoneum, perirectal area, and buttock in 1 patient each. Lesions measured 2.3 to 19.5 cm. Complete excision was done in 8 patients. One perirectal tumor was removed by both the posterior sagittal approach and the intraabdominal approach but incompletely resected. Two tumors located on the back recurred with intraspinal extension 12 months and 18 months after resection. Second resection and second resection with laminectomy were done. Leg pain and urinary incontinence developed in 1 patient but improved on conservative treatment.Lipoblastoma is a benign neoplasm but can frequently recur (25%) in spite of complete excision. Lipoblastomas occurring on the back had a high recurrence rate (50%) and associated with intraspinal extension. J Pediatr Surg 36:905-907.
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- 2001
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15. Radioisotope synoviorthesis with Holmium-166-chitosan complex in haemophilic arthropathy
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K. H. Rhyu, Kang-Il Kim, D. Y. Kim, Y. S. Chun, Myung Chul Yoo, B. K. Kwon, and Y. J. Cho
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Adult ,musculoskeletal diseases ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Radiography ,Elbow ,Synovectomy ,Knee Joint ,Hemophilia A ,Haemophilia ,Hemostatics ,Injections, Intra-Articular ,Holmium ,Young Adult ,Hemarthrosis ,Humans ,Medicine ,Range of Motion, Articular ,Child ,Genetics (clinical) ,Radioisotopes ,Chitosan ,business.industry ,Incidence ,Synovial Membrane ,Hematology ,General Medicine ,medicine.disease ,Surgery ,Drug Combinations ,medicine.anatomical_structure ,Child, Preschool ,Ankle ,business ,Complication ,Range of motion - Abstract
Radiosynoviorthesis is a safe and easy method for synovectomy in haemophilic arthropathy. Various agents have been used in radiosynoviorthesis, especially newly developed agent Holmium-166-chitosan complex has good clinical outcome. This study analysed clinical results and radiologic evaluation of radioisotope synoviorthesis using Holmium-166-chitosan complex in haemophilic arthropathy. From March 2001 to December 2003, 58 radiosynoviorthesis were performed in 53 haemophiliacs. The average age at procedure was 13.8 years. The Arnold and Hilgartner stage of the patients was from I to IV. Holmium-166-chitosan complex was injected in 31 ankle joints, 19 elbow joints and 8 knee joints. Average follow-up was 33 months since primary procedure. The range of motion of each joint, frequency of intra-articular bleeding and factor dose used were analysed for clinical assessment. There was no significant improvement of range of motion in affected joints. After procedure, the average frequency of bleeding of the elbow joint has decreased from 3.76 to 0.47 times per month, the knee joint from 5.87 to 1.12 times per month, and the ankle joint from 3.62 to 0.73 times per month respectively (P < 0.05). After treatment, the average coagulation factor dose injected was significantly decreased to 779.3 units per month from 2814.8 units per month before treatment (P < 0.001). Radioisotope synoviorthesis with Holmium-166-chitosan complex in haemophilic arthropathy is a very safe and simple procedure with the expectation of a satisfactory outcome without serious complication. It has excellent bleeding control effect on target joint and the need for substitution of coagulation factor concentrate can be reduced.
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- 2010
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16. Bone density at interradicular sites: implications for orthodontic mini-implant placement
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Y. S. Chun and Woo Hyeon Lim
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Adult ,Male ,Bone density ,Dentistry ,Orthodontics ,Computed tomographic ,Young Adult ,Bone Density ,Hounsfield scale ,Alveolar Process ,Orthodontic Anchorage Procedures ,Medicine ,Humans ,Dental Implants ,Miniaturization ,business.industry ,Dental Implantation, Endosseous ,Mandible ,Otorhinolaryngology ,Mini implants ,Maxilla ,Surgery ,Female ,Implant ,Oral Surgery ,business ,Tomography, X-Ray Computed - Abstract
Structured Abstract Authors – Chun YS, Lim WH Objectives – Implant stability is primarily related to local bone density; Few studies have evaluated interradicular bone density related to mini-implant placement for orthodontic anchorage. Therefore, this study evaluated bone density differences between interradicular sites. Setting and Sample Population – Computed tomographic (CT) images were obtained from 14 males and 14 females (mean age 27 years, range 23–35 years). Bone density in Hounsfield units (HU) was measured at 13 interradicular sites and four bone levels. Results – Bone densities in most areas were higher than 850 HU. Statistically significant differences in bone density were detected at different levels and sites. Bone densities in both maxilla and mandible significantly increased from the alveolar crest toward basal bone in posterior areas, while the opposite was observed in anterior areas. There were statistically significant differences in bone densities between the maxilla and mandible in posterior areas. Bone densities progressively increased from anterior to posterior areas in the mandible. Conclusion – The results suggest that mini-implants for orthodontic anchorage may be effective when placed in most areas with equivalent bone density up to 6 mm apical to the alveolar crest. Site selection should be adjusted according to bone density assessment.
- Published
- 2009
17. Limitation of WSix/WN Diffusion Barrier for Tungsten Dual Polymetal Gate Memory Devices
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Kwan-Yong Lim, H.-S. Yang, Yong-Taik Kim, Seung-Woo Shin, W.-K. Ma, G.-H. Kim, Se-kyoung Choi, S.-R. Won, Kyeong-Keun Choi, Yong Soo Kim, Seung Ryong Lee, Whoi-Yul Kim, S.-A. Jang, J.-H. Han, H.-J. Cho, Y.-S. Chun, Y.-K. Jung, Tae-Un Youn, Se-Jun Kim, Yunbong Lee, Jin Kim, S.-Y. Koo, Min Gyu Sung, Seung-Ho Pyi, Kyungdo Kim, J.-K. Lee, T.-K. Oh, and Y.-T. Hwang
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Materials science ,Diffusion barrier ,business.industry ,Polymetal ,Oxide ,chemistry.chemical_element ,Dielectric ,Tungsten ,chemistry.chemical_compound ,chemistry ,Gate oxide ,Electronic engineering ,Optoelectronics ,Diffusion (business) ,business ,AND gate - Abstract
We compared WSix/WN and Ti/WN diffusion barriers for tungsten dual polymetal gate (W-DPG) application, in terms of device performance and gate oxide reliability. WSix/WN diffusion barrier shows degradation of gate oxide, which is found to be due to the B-N dielectric formation and subsequent breakdown of diffusion barrier. Relatively, Ti/WN diffusion barrier shows excellent device performance in terms of R/O delay and gate oxide reliability
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- 2007
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18. Effects of V/III ratio on ordering and antiphase boundaries in GaInP layers
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Y. S. Chun, Joon Hyung Kim, Tae Yeon Seong, and Gerald B. Stringfellow
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Crystallography ,Materials science ,Physics and Astronomy (miscellaneous) ,Electron diffraction ,Transmission electron microscopy ,Vapor phase ,Heterojunction ,Degree of order ,Epitaxy ,Layer (electronics) ,Vicinal - Abstract
Transmission electron microscope (TEM) and transmission electron diffraction (TED) studies have been performed to investigate the effects of V/III ratio on ordering and antiphase boundaries (APBs) in organometallic vapor phase epitaxial Ga0.5In0.5P layers grown onto (001) GaAs vicinal substrates at 670 °C. TED and TEM examination showed that the degree of order is higher in the layer grown using a V/III ratio of 160 than in the layer grown using a V/III ratio of 40. TEM results showed that the higher V/III ratio could be used to suppress APBs. In addition, the growth of order-induced heterostructures, where the V/III ratio is increased abruptly during growth, could be used to block the propagation of APBs. Mechanisms are proposed to explain these phenomena.
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- 1997
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19. Use of bonded power arms for interdental space closure
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Y S, Chun, Y J, Woo, and J, Row
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Adult ,Tooth Movement Techniques ,Surface Properties ,Diastema ,Stainless Steel ,Incisor ,Dental Arch ,Orthodontic Appliances ,Maxilla ,Orthodontic Wires ,Humans ,Orthodontic Appliance Design ,Female ,Malocclusion ,Periodontal Diseases - Published
- 2001
20. Germline E-cadherin gene mutations: is prophylactic total gastrectomy indicated?
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Y S, Chun, N M, Lindor, T C, Smyrk, B T, Petersen, L J, Burgart, P J, Guilford, and J H, Donohue
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Adult ,Male ,Primary Prevention ,Gastrectomy ,Stomach Neoplasms ,Humans ,Female ,Genetic Predisposition to Disease ,Middle Aged ,Cadherins ,Germ-Line Mutation - Abstract
The CDH1 gene encodes E-cadherin, an epithelial cell adhesion molecule. Germline CDH1 mutations recently were identified in families with hereditary diffuse gastric carcinoma in a pattern suggestive of autosomal dominant inheritance with incomplete penetrance.The proband was a woman age 47 years with a strong family history of diffuse gastric carcinoma. A germline E-cadherin gene mutation was identified in this patient, her brother, and three first cousins. All five family members underwent endoscopic evaluations, which were negative for malignancy, and elected to undergo a prophylactic total gastrectomy with Roux-en-Y esophagojejunostomy.Pathologic examination of the proband's stomach revealed several microscopic foci of intramucosal signet ring cell adenocarcinoma in the cardia and proximal gastric body. Postgastrectomy specimens from the proband's brother and three first cousins all showed intramucosal signet ring cell adenocarcinoma in various regions of the stomach. Immunoperoxidase studies performed on gastric tissue from these five patients demonstrated diminished or absent E-cadherin reactivity in the cancerous mucosa.Although total gastrectomy was performed as a prophylactic intervention, occult gastric carcinoma was discovered in all five patients. Thus, total gastrectomy should be curative for gastric carcinoma in these patients. Based on their successful outcomes and the lack of efficacious surveillance methods for diffuse gastric carcinoma, prophylactic total gastrectomy may be the management of choice for germline E-cadherin gene mutation carriers. However, prophylactic total gastrectomy should be undertaken cautiously because the procedure may be associated with considerable morbidity.
- Published
- 2001
21. Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells
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Y S, Chun, E J, Yeo, E, Choi, C M, Teng, J M, Bae, M S, Kim, and J W, Park
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Vascular Endothelial Growth Factor A ,Lymphokines ,Indazoles ,Vascular Endothelial Growth Factors ,Enzyme Activators ,Nuclear Proteins ,Endothelial Growth Factors ,Hypoxia-Inducible Factor 1, alpha Subunit ,Cell Hypoxia ,DNA-Binding Proteins ,Oxygen ,Tumor Cells, Cultured ,Humans ,Drug Interactions ,Hypoxia-Inducible Factor 1 ,Cyclic GMP ,Erythropoietin ,Transcription Factors - Abstract
YC-1 is a newly developed agent that inhibits platelet aggregation and vascular contraction. Although its effects are independent of nitric oxide (NO), it mimics some of the biological actions of NO. For example, it stimulates soluble guanylate cyclase (sGC) and increases intracellular cGMP concentration. Here, we tested the possibility that YC-1 inhibits hypoxia-inducible factor (HIF)-1-mediated hypoxic responses, as does NO. Hep3B cells were used during the course of this work to observe hypoxic induction of erythropoietin (EPO) and vascular endothelial growth factor (VEGF), and the effects of YC-1 were compared with those of a NO donor, sodium nitropurruside (SNP). In hypoxic cells, YC-1 blocked the induction of EPO and VEGF mRNAs, and inhibited the DNA-binding activity of HIF-1. It suppressed the hypoxic accumulation of HIF-1alpha, but not its mRNA level. It also reduced HIF-1alpha accumulation induced by cobalt and desferrioxamine. Treatment with antioxidants did not recover the HIF-1alpha suppressed by YC-1. We examined whether these effects of YC-1 are related to the sGC/cGMP signal transduction system. Two sGC inhibitors examined failed to block the effects of YC-1, and 8-bromo-cGMP did not mimic actions of YC-1. The effects of YC-1 on the hypoxic responses were comparable with those of SNP. These results suggest that YC-1 and SNP suppressed the hypoxic responses by post-translationally inhibiting HIF-1alpha accumulation. The YC-1 effect may be linked with the metal-related oxygen sensing pathway, and is not due to the stimulation of sGC. This observation implies that the inhibitory effects of YC-1 on hypoxic responses can be developed to suppress EPO-overproduction by tumor cells and tumor angiogenesis.
- Published
- 2001
22. Cytoprotective effect of arginine deiminase on taxol-induced apoptosis in DU145 human prostate cancer cells
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S W, Kang, H, Kang, I S, Park, S H, Choi, K H, Shin, Y S, Chun, B G, Chun, and B H, Min
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Lipopolysaccharides ,Male ,Protein Synthesis Inhibitors ,Sertoli Cells ,L-Lactate Dehydrogenase ,Paclitaxel ,Hydrolases ,Molecular Sequence Data ,G1 Phase ,Prostatic Neoplasms ,Apoptosis ,DNA Fragmentation ,Arginine ,Nitric Oxide ,Cell Line ,Rats ,Cytoprotection ,Astrocytes ,Culture Media, Conditioned ,Tumor Cells, Cultured ,Animals ,Humans ,Amino Acid Sequence ,Cycloheximide ,Sequence Alignment - Abstract
We purified and partially sequenced a cytostatic protein from the ASC-17D Sertoli cell-conditioned media (rSCCM) showing a molecular weight of 90 kDa with homodimeric composition. N-terminal amino acid analysis revealed that the protein was homologous to the arginine deiminase (ADI) of Mycoplasma arginini. We found ADI enzyme activity in rSCCM and the abolishment of the growth inhibitory effect by the supplement of L-arginine. Thus, we confirmed that the cytostatic activity in rSCCM was due to the depletion of extracellular L-arginine by ADI. Apparent increase of cell death or DNA fragmentation was not observed in DU145 cells cultured in the presence of ADI. Incubation of DU145 cancer cells with taxol resulted in a marked DNA fragmentation, whereas pretreatment with ADI or cycloheximide protected the cells from taxol-induced apoptosis. Preincubation of the cells with ADI inhibited S35-methionine incorporation into protein synthesis in a dose dependent manner. These data suggest that ADI-induced arginine depletion may inhibit protein synthesis, and result in the protection of apoptotic cell death that requires new protein synthesis.
- Published
- 2000
23. A new appliance for orthopedic correction of Class III malocclusion
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Y S, Chun, S G, Jeong, J, Row, and S J, Yang
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Malocclusion, Angle Class III ,Humans ,Orthodontic Appliance Design ,Female ,Child ,Orthodontics, Corrective - Published
- 2000
24. Management of extruded maxillary molars to accommodate a mandibular restoration: a clinical report
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Y S, Chun, J, Row, S J, Yang, H S, Cha, and J S, Han
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Adult ,Male ,Radiography ,Tooth Movement Techniques ,Denture, Partial, Temporary ,Jaw, Edentulous, Partially ,Maxilla ,Denture, Partial, Fixed ,Humans ,Dental Prosthesis, Implant-Supported ,Mandible ,Tooth Migration ,Molar - Published
- 2000
25. Hypnotic activities of N3-benzyl and xylyl substituted arabinofuranosyluracil
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T, Kimura, Y S, Chun, M, Ikeda, K, Kobana, K, Watanabe, S, Kondo, I K, Ho, and I, Yamamoto
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Mice ,Structure-Activity Relationship ,Time Factors ,Molecular Structure ,Arabinofuranosyluracil ,Animals ,Hypnotics and Sedatives ,Sleep ,Pentobarbital ,Cerebral Ventricles ,Injections, Intraventricular - Abstract
N3-Substituted derivatives of arabinofuranosyluracil (1), methyl (2), ethyl (3), propyl (4), butyl (5), allyl (6), benzyl (7), o-, m-, p-xylyls (8, 9, 10) and alpha-phenethyl (11) derivatives, were synthesized and their CNS depressant effects were evaluated by intracerebroventricular (i.c.v.) injection in mice by using hypnotic activity and pentobarbital-induced sleep prolongation as indices. At a dose of 2.0 mumol/mouse, the values of mean sleeping time induced by 7, 8, 9, and 10 were 144, 154, 117, and 33 min, respectively. Although the alkyl (2-6) derivatives did not cause any hypnotic activity, some derivatives tested (5, 7-10) significantly prolonged the pentobarbital-induced sleeping time.
- Published
- 1997
26. Myc target genes in neoplastic transformation
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H, Shim, B C, Lewis, C, Dolde, Q, Li, C S, Wu, Y S, Chun, and C V, Dang
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Gene Expression Regulation, Neoplastic ,Cell Transformation, Neoplastic ,Genes, myc ,Animals ,Humans ,Apoptosis ,Cell Differentiation ,Cloning, Molecular ,Cell Division - Published
- 1997
27. Ischemic preconditioning reduces Op6 generation and prevents respiratory impairment in the mitochondria of post-ischemic reperfused heart of rat
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J W, Park, Y S, Chun, Y H, Kim, C H, Kim, and M S, Kim
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Male ,Lipid Peroxides ,Free Radicals ,Myocardial Reperfusion Injury ,Antioxidants ,Cell Hypoxia ,Mitochondria, Heart ,Rats ,Oxygen ,Rats, Sprague-Dawley ,Oxygen Consumption ,Ischemic Preconditioning, Myocardial ,Amobarbital ,Animals - Abstract
The present study was performed to test whether the ischemic preconditioning could reduce mitochondrial O2.- production and prevent mitochondrial respiratory impairment upon reperfusion of ischemic hearts. The isolated perfused rat hearts were subjected to 30 min of global ischemia and 20 min of reperfusion. Ischemic preconditioning was performed, involving three 5-min periods of ischemia, each followed by a 5-min reperfusion just before a sustained ischemia. Ischemic preconditioning improved the post-ischemic cardiac function and reduced LDH release and malondialdehyde production upon reperfusion. 02.- generation of mitochondria isolated from the preconditioned hearts was significantly lower than that of mitochondria from the non-preconditioned hearts, and none of the activities of mitochondrial antioxidant enzymes (SOD, catalase, glutathione peroxidase) was altered as a consequence of the ischemic preconditioning alone. The impairment of mitochondrial state 3 respiration induced by ischemia and reperfusion was prevented by ischemic preconditioning. Amytal, a reversible respiratory chain blocker suppressing 02.- production in mitochondria, prevented the ischemia/reperfusion injury. The cardioprotective effect of Amytal could not be distinguished from that of ischemic preconditioning. These results suggest that the cardioprotective effect of ischemic preconditioning against the ischemia/reperfusion injury is attributed partly to the reduction of mitochondrial oxygen radical generation and prevention of the respiratory impairment during ischemia and reperfusion.
- Published
- 1997
28. Compositional Ordering in GalnP for Heterostructure Formation
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T. C. Hsu, Y. Hosokawa, L. C. Su, Y. S. Chun, I. H. Ho, Gerald B. Stringfellow, and H. Murata
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Materials science ,Chemical physics ,Band gap ,Bilayer ,Monolayer ,Heterojunction ,Substrate (electronics) ,Epitaxy ,Vicinal ,Surface reconstruction - Abstract
Compositional ordering is observed in essentially all IIIN semiconductor alloys. The mechanism leading to the specific ordered structures formed is only now beginning to be understood. It is intimately related to the atomic-scale physical processes occurring on the surface during epitaxial growth, specifically surface reconstruction and the attachment of atoms at steps. This paper will emphasize the use of surface analytic techniques to better understand the ordering processes during organometallic vapor phase epitaxial growth of GalnP. Surface photo absorption has been used to determine, for the first time, that the surface reconstruction is (2×4)-like during growth of GalnP with Cu-Pt ordering. By increasing the growth temperature and/or decreasing the V/Ill ratio the concentration of phosphorus dimers characteristic of the (2×4) structure is observed to decrease in tandem with a decrease in the degree of order measured in the epitaxial layers. This suggests that formation of the (2×4) reconstruction is necessary for formation of the Cu-Pt ordered structure.Atomic force microscopy was used to examine the step structure. For exactly (001)-oriented substrates, growth at low V/Ill ratios produces islands surrounded by single monolayer steps. Increasing the V/Ill ratio leads to the formation of bilayer steps approximately 6 Å high. A similar change in the structure of steps is observed in the vicinal regions for substrates misoriented to produce [110] steps. This phenomenon is interpreted in terms of the stabilization, at high V/Ill ratios, of the (2×2) reconstruction on the (111)B regions of the bilayer steps. This may also have an effect on formation of the Cu-Pt ordered structure.By changing the substrate temperature or the input partial pressure of the phosphorus precursor, the degree of order and, hence, the bandgap energy of GalnP, can be modulated during growth. This has allowed the production of a variety of single and double heterostructures. The heterostructures produced by changing the temperature from 740 to 620°C and from 620 to 520°C are abrupt. The heterostructures formed by changing the phosphine flow rate are not. The ordered structure in the lower layer persists into the upper layer. This may be an indication of the importance of the step structure.
- Published
- 1995
- Full Text
- View/download PDF
29. Identification of PP1 catalytic subunit isotypes PP1 gamma 1, PP1 delta and PP1 alpha in various rat tissues
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H, Shima, Y, Hatano, Y S, Chun, T, Sugimura, Z, Zhang, E Y, Lee, and M, Nagao
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Male ,Macromolecular Substances ,Molecular Sequence Data ,Gene Expression ,Blotting, Northern ,Antibodies ,Rats, Inbred F344 ,Rats ,Isoenzymes ,Molecular Weight ,Antibody Specificity ,Organ Specificity ,Protein Phosphatase 1 ,Phosphoprotein Phosphatases ,Animals ,RNA ,Amino Acid Sequence ,RNA, Messenger ,Cloning, Molecular ,Peptides - Abstract
cDNA clones for 4 rat protein phosphatase 1 (PP1) catalytic subunit isotypes, PP1 alpha, PP1 gamma 1, PP1 gamma 2 and PP1 delta, were isolated (K. Sasaki et al., Jpn. J. Cancer Res. 81, 1272-1280, 1990). Antibodies were raised to determine the physiological functions of 4 isotypes. Among these isotypes, the PP1 gamma 2 protein was detected specifically in rat testis (H. Shima et al., Adv. Prot. Phosphatases, vol. 7, in press). On the other hand, PP1 gamma 1, PP1 delta and PP1 alpha were detected as 36kDa, 37kDa and 38kDa proteins in several rat organs by immunoblot analysis. All three isotypes were found in both soluble and particulate fractions. PP1 gamma 1 was predominant in the brain and PP1 delta in the brain, lung and small intestine, but the levels of both were low in the liver and muscle. It became evident that PP1 alpha was not a predominant isotype in any tissue examined.
- Published
- 1993
30. Investigation of magnetic structure and magnetization process of yttrium iron garnet film by Lorentz microscopy and electron holography
- Author
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Y. S. Chun, Kannan M. Krishnan, Keiichi Yanagisawa, Weixing Xia, A. Tonomura, Daisuke Shindo, and Shinji Aizawa
- Subjects
Materials science ,Magnetic domain ,Condensed matter physics ,business.industry ,Yttrium iron garnet ,General Physics and Astronomy ,Electron holography ,Condensed Matter::Materials Science ,Magnetic anisotropy ,chemistry.chemical_compound ,Magnetization ,Optics ,chemistry ,Single domain ,Magnetic force microscope ,business ,human activities ,Saturation (magnetic) - Abstract
The micromagnetic structure and magnetization process of perpendicular Y3Fe5O12 (YIG) films were studied by Lorentz microscopy and electron holography. The closure domain structure inside the thin transmission electron microscopy specimen exhibits the same period as the magnetization pattern observed by magnetic force microscopy indicating the perpendicular anisotropy of the YIG film. Through observation of stray fields, it is concluded that the shapes of domain and domain walls are sensitive to the specimen thickness; moreover, a closure domain configuration observed in thin specimen is the stable energy state as determined by the balance between the crystalline anisotropy and shape anisotropy. Domain wall movement is observed by applying a magnetic field, in situ, inside the microscope in both horizontal and perpendicular directions; the saturation fields observed are qualitatively in agreement with the results of the hysteresis loop.
- Published
- 2010
- Full Text
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31. Significance of pathologic response to preoperative therapy in pancreatic cancer
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Y. S. Chun, H. S. Cooper, J. C. Watson, and J. P. Hoffman
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Cancer Research ,Oncology - Published
- 2010
- Full Text
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32. Palladium Nanoparticles Supported onto Ionic Carbon Nanotubes
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Y. S. Chun, J. Y. Shin, S.-g Lee, and C. E. Song
- Subjects
Chemical engineering ,law ,Chemistry ,Selective chemistry of single-walled nanotubes ,Palladium nanoparticles ,Ionic bonding ,Carbon nanotube supported catalyst ,Carbon nanotube ,law.invention - Published
- 2008
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33. A search for a doubly-charged Higgs boson in pp collisions at $\sqrt{s} = 7 \ \mbox{TeV}$
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The CMS Collaboration, S. Chatrchyan, V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, M. Friedl, R. Frühwirth, V. M. Ghete, J. Hammer, N. Hörmann, J. Hrubec, M. Jeitler, W. Kiesenhofer, V. Knünz, M. Krammer, D. Liko, I. Mikulec, M. Pernicka, B. Rahbaran, C. Rohringer, H. Rohringer, R. Schöfbeck, J. Strauss, A. Taurok, P. Wagner, W. Waltenberger, G. Walzel, E. Widl, C.-E. Wulz, V. Mossolov, N. Shumeiko, J. Suarez Gonzalez, S. Bansal, T. Cornelis, E. A. De Wolf, X. Janssen, S. Luyckx, T. Maes, L. Mucibello, S. Ochesanu, B. Roland, R. Rougny, M. Selvaggi, Z. Staykova, H. Van Haevermaet, P. Van Mechelen, N. Van Remortel, A. Van Spilbeeck, F. Blekman, S. Blyweert, J. D’Hondt, R. Gonzalez Suarez, A. Kalogeropoulos, M. Maes, A. Olbrechts, W. Van Doninck, P. Van Mulders, G. P. Van Onsem, I. Villella, O. Charaf, B. Clerbaux, G. De Lentdecker, V. Dero, A. P. R. Gay, T. Hreus, A. Léonard, P. E. Marage, T. Reis, L. Thomas, C. Vander Velde, P. Vanlaer, J. Wang, V. Adler, K. Beernaert, A. Cimmino, S. Costantini, G. Garcia, M. Grunewald, B. Klein, J. Lellouch, A. Marinov, J. Mccartin, A. A. Ocampo Rios, D. Ryckbosch, N. Strobbe, F. Thyssen, M. Tytgat, L. Vanelderen, P. Verwilligen, S. Walsh, E. Yazgan, N. Zaganidis, S. Basegmez, G. Bruno, R. Castello, A. Caudron, L. Ceard, C. Delaere, T. du Pree, D. Favart, L. Forthomme, A. Giammanco, J. Hollar, V. Lemaitre, J. Liao, O. Militaru, C. Nuttens, D. Pagano, L. Perrini, A. Pin, K. Piotrzkowski, N. Schul, J. M. Vizan Garcia, N. Beliy, T. Caebergs, E. Daubie, G. H. Hammad, G. A. Alves, M. Correa Martins Junior, D. De Jesus Damiao, T. Martins, M. E. Pol, M. H. G. Souza, W. L. Aldá Júnior, W. Carvalho, A. Custódio, E. M. Da Costa, C. De Oliveira Martins, S. Fonseca De Souza, D. Matos Figueiredo, L. Mundim, H. Nogima, V. Oguri, W. L. Prado Da Silva, A. Santoro, L. Soares Jorge, A. Sznajder, C. A. Bernardes, F. A. Dias, T. R. Fernandez Perez Tomei, E. M. Gregores, C. Lagana, F. Marinho, P. G. Mercadante, S. F. Novaes, Sandra S. Padula, V. Genchev, P. Iaydjiev, S. Piperov, M. Rodozov, S. Stoykova, G. Sultanov, V. Tcholakov, R. Trayanov, M. Vutova, A. Dimitrov, R. Hadjiiska, V. Kozhuharov, L. Litov, B. Pavlov, P. Petkov, J. G. Bian, G. M. Chen, H. S. Chen, C. H. Jiang, D. Liang, S. Liang, X. Meng, J. Tao, X. Wang, Z. Wang, H. Xiao, M. Xu, J. Zang, Z. Zhang, C. Asawatangtrakuldee, Y. Ban, S. Guo, Y. Guo, W. Li, S. Liu, Y. Mao, S. J. Qian, H. Teng, S. Wang, B. Zhu, W. Zou, C. Avila, J. P. Gomez, B. Gomez Moreno, A. F. Osorio Oliveros, J. C. Sanabria, N. Godinovic, D. Lelas, R. Plestina, D. Polic, I. Puljak, Z. Antunovic, M. Kovac, V. Brigljevic, S. Duric, K. Kadija, J. Luetic, S. Morovic, A. Attikis, M. Galanti, G. Mavromanolakis, J. Mousa, C. Nicolaou, F. Ptochos, P. A. Razis, M. Finger, Y. Assran, S. Elgammal, A. Ellithi Kamel, S. Khalil, M. A. Mahmoud, A. Radi, M. Kadastik, M. Müntel, M. Raidal, L. Rebane, A. Tiko, V. Azzolini, P. Eerola, G. Fedi, M. Voutilainen, J. Härkönen, A. Heikkinen, V. Karimäki, R. Kinnunen, M. J. Kortelainen, T. Lampén, K. Lassila-Perini, S. Lehti, T. Lindén, P. Luukka, T. Mäenpää, T. Peltola, E. Tuominen, J. Tuominiemi, E. Tuovinen, D. Ungaro, L. Wendland, K. Banzuzi, A. Karjalainen, A. Korpela, T. Tuuva, M. Besancon, S. Choudhury, M. Dejardin, D. Denegri, B. Fabbro, J. L. Faure, F. Ferri, S. Ganjour, A. Givernaud, P. Gras, G. Hamel de Monchenault, P. Jarry, E. Locci, J. Malcles, L. Millischer, A. Nayak, J. Rander, A. Rosowsky, I. Shreyber, M. Titov, S. Baffioni, F. Beaudette, L. Benhabib, L. Bianchini, M. Bluj, C. Broutin, P. Busson, C. Charlot, N. Daci, T. Dahms, L. Dobrzynski, R. Granier de Cassagnac, M. Haguenauer, P. Miné, C. Mironov, M. Nguyen, C. Ochando, P. Paganini, D. Sabes, R. Salerno, Y. Sirois, C. Veelken, A. Zabi, J.-L. Agram, J. Andrea, D. Bloch, D. Bodin, J.-M. Brom, M. Cardaci, E. C. Chabert, C. Collard, E. Conte, F. Drouhin, C. Ferro, J.-C. Fontaine, D. Gelé, U. Goerlach, P. Juillot, A.-C. Le Bihan, P. Van Hove, F. Fassi, D. Mercier, S. Beauceron, N. Beaupere, O. Bondu, G. Boudoul, H. Brun, J. Chasserat, R. Chierici, D. Contardo, P. Depasse, H. El Mamouni, J. Fay, S. Gascon, M. Gouzevitch, B. Ille, T. Kurca, M. Lethuillier, L. Mirabito, S. Perries, V. Sordini, S. Tosi, Y. Tschudi, P. Verdier, S. Viret, Z. Tsamalaidze, G. Anagnostou, S. Beranek, M. Edelhoff, L. Feld, N. Heracleous, O. Hindrichs, R. Jussen, K. Klein, J. Merz, A. Ostapchuk, A. Perieanu, F. Raupach, J. Sammet, S. Schael, D. Sprenger, H. Weber, B. Wittmer, V. Zhukov, M. Ata, J. Caudron, E. Dietz-Laursonn, D. Duchardt, M. Erdmann, R. Fischer, A. Güth, T. Hebbeker, C. Heidemann, K. Hoepfner, D. Klingebiel, P. Kreuzer, J. Lingemann, C. Magass, M. Merschmeyer, A. Meyer, M. Olschewski, P. Papacz, H. Pieta, H. Reithler, S. A. Schmitz, L. Sonnenschein, J. Steggemann, D. Teyssier, M. Weber, M. Bontenackels, V. Cherepanov, G. Flügge, H. Geenen, M. Geisler, W. Haj Ahmad, F. Hoehle, B. Kargoll, T. Kress, Y. Kuessel, A. Nowack, L. Perchalla, O. Pooth, J. Rennefeld, P. Sauerland, A. Stahl, M. Aldaya Martin, J. Behr, W. Behrenhoff, U. Behrens, M. Bergholz, A. Bethani, K. Borras, A. Burgmeier, A. Cakir, L. Calligaris, A. Campbell, E. Castro, F. Costanza, D. Dammann, G. Eckerlin, D. Eckstein, G. Flucke, A. Geiser, I. Glushkov, P. Gunnellini, S. Habib, J. Hauk, G. Hellwig, H. Jung, M. Kasemann, P. Katsas, C. Kleinwort, H. Kluge, A. Knutsson, M. Krämer, D. Krücker, E. Kuznetsova, W. Lange, W. Lohmann, B. Lutz, R. Mankel, I. Marfin, M. Marienfeld, I.-A. Melzer-Pellmann, A. B. Meyer, J. Mnich, A. Mussgiller, S. Naumann-Emme, J. Olzem, H. Perrey, A. Petrukhin, D. Pitzl, A. Raspereza, P. M. Ribeiro Cipriano, C. Riedl, E. Ron, M. Rosin, J. Salfeld-Nebgen, R. Schmidt, T. Schoerner-Sadenius, N. Sen, A. Spiridonov, M. Stein, R. Walsh, C. Wissing, C. Autermann, V. Blobel, S. Bobrovskyi, J. Draeger, H. Enderle, J. Erfle, U. Gebbert, M. Görner, T. Hermanns, R. S. Höing, K. Kaschube, G. Kaussen, H. Kirschenmann, R. Klanner, J. Lange, B. Mura, F. Nowak, T. Peiffer, N. Pietsch, D. Rathjens, C. Sander, H. Schettler, P. Schleper, E. Schlieckau, A. Schmidt, M. Schröder, T. Schum, M. Seidel, H. Stadie, G. Steinbrück, J. Thomsen, C. Barth, J. Berger, C. Böser, T. Chwalek, W. De Boer, A. Descroix, A. Dierlamm, M. Feindt, M. Guthoff, C. Hackstein, F. Hartmann, T. Hauth, M. Heinrich, H. Held, K. H. Hoffmann, S. Honc, I. Katkov, J. R. Komaragiri, D. Martschei, S. Mueller, Th. Müller, M. Niegel, A. Nürnberg, O. Oberst, A. Oehler, J. Ott, G. Quast, K. Rabbertz, F. Ratnikov, N. Ratnikova, S. Röcker, A. Scheurer, F.-P. Schilling, G. Schott, H. J. Simonis, F. M. Stober, D. Troendle, R. Ulrich, J. Wagner-Kuhr, S. Wayand, T. Weiler, M. Zeise, G. Daskalakis, T. Geralis, S. Kesisoglou, A. Kyriakis, D. Loukas, I. Manolakos, A. Markou, C. Markou, C. Mavrommatis, E. Ntomari, L. Gouskos, T. J. Mertzimekis, A. Panagiotou, N. Saoulidou, I. Evangelou, C. Foudas, P. Kokkas, N. Manthos, I. Papadopoulos, V. Patras, G. Bencze, C. Hajdu, P. Hidas, D. Horvath, F. Sikler, V. Veszpremi, G. Vesztergombi, N. Beni, S. Czellar, J. Molnar, J. Palinkas, Z. Szillasi, J. Karancsi, P. Raics, Z. L. Trocsanyi, B. Ujvari, S. B. Beri, V. Bhatnagar, N. Dhingra, R. Gupta, M. Jindal, M. Kaur, M. Z. Mehta, N. Nishu, L. K. Saini, A. Sharma, J. Singh, Ashok Kumar, Arun Kumar, S. Ahuja, A. Bhardwaj, B. C. Choudhary, S. Malhotra, M. Naimuddin, K. Ranjan, V. Sharma, R. K. Shivpuri, S. Banerjee, S. Bhattacharya, S. Dutta, B. Gomber, Sa. Jain, Sh. Jain, R. Khurana, S. Sarkar, M. Sharan, A. Abdulsalam, R. K. Choudhury, D. Dutta, S. Kailas, V. Kumar, P. Mehta, A. K. Mohanty, L. M. Pant, P. Shukla, T. Aziz, S. Ganguly, M. Guchait, M. Maity, G. Majumder, K. Mazumdar, G. B. Mohanty, B. Parida, K. Sudhakar, N. Wickramage, S. Dugad, H. Arfaei, H. Bakhshiansohi, S. M. Etesami, A. Fahim, M. Hashemi, A. Jafari, M. Khakzad, A. Mohammadi, M. Mohammadi Najafabadi, S. Paktinat Mehdiabadi, B. Safarzadeh, M. 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Balazs, S. Boutle, B. Cox, B. Francis, J. Goodell, R. Hirosky, A. Ledovskoy, C. Lin, C. Neu, J. Wood, R. Yohay, S. Gollapinni, R. Harr, P. E. Karchin, C. Kottachchi Kankanamge Don, P. Lamichhane, A. Sakharov, M. Anderson, M. Bachtis, D. Belknap, L. Borrello, D. Carlsmith, M. Cepeda, S. Dasu, L. Gray, K. S. Grogg, M. Grothe, R. Hall-Wilton, M. Herndon, A. Hervé, P. Klabbers, J. Klukas, A. Lanaro, C. Lazaridis, J. Leonard, R. Loveless, A. Mohapatra, I. Ojalvo, F. Palmonari, G. A. Pierro, I. Ross, A. Savin, W. H. Smith, and J. Swanson
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract A search for a doubly-charged Higgs boson in pp collisions at $\sqrt{s} = 7 \ \mbox{TeV}$ is presented. The data correspond to an integrated luminosity of 4.9 fb−1, collected by the CMS experiment at the LHC. The search is performed using events with three or more isolated charged leptons of any flavor, giving sensitivity to the decays of pair-produced triplet components Φ ++ Φ −−, and Φ ++ Φ − from associated production. No excess is observed compared to the background prediction, and upper limits at the 95 % confidence level are set on the Φ ++ production cross section, under specific assumptions on its branching fractions. Lower bounds on the Φ ++ mass are reported, providing significantly more stringent constraints than previously published limits.
- Published
- 2012
- Full Text
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34. Ratios of dijet production cross sections as a function of the absolute difference in rapidity between jets in proton–proton collisions at $\sqrt{s} = 7\ \mathrm{TeV}$
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Harr, P. E. Karchin, C. Kottachchi Kankanamge Don, P. Lamichhane, M. Mattson, C. Milstène, A. Sakharov, M. Anderson, M. Bachtis, D. Belknap, J. N. Bellinger, J. Bernardini, L. Borrello, D. Carlsmith, M. Cepeda, S. Dasu, J. Efron, E. Friis, L. Gray, K. S. Grogg, M. Grothe, R. Hall-Wilton, M. Herndon, A. Hervé, P. Klabbers, J. Klukas, A. Lanaro, C. Lazaridis, J. Leonard, R. Loveless, A. Mohapatra, I. Ojalvo, G. A. Pierro, I. Ross, A. Savin, W. H. Smith, and J. Swanson
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract A study of dijet production in proton–proton collisions was performed at $\sqrt{s}=7\mbox{~TeV}$ for jets with p T>35 GeV and |y|
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- 2012
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35. Centrality dependence of dihadron correlations and azimuthal anisotropy harmonics in PbPb collisions at $\sqrt{s_{NN}}= 2.76\ \mbox{TeV}$
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The CMS Collaboration, S. Chatrchyan, V. Khachatryan, A. M. Sirunyan, A. Tumasyan, W. Adam, T. Bergauer, M. Dragicevic, J. Erö, C. Fabjan, M. Friedl, R. Frühwirth, V. M. Ghete, J. Hammer, M. Hoch, N. Hörmann, J. Hrubec, M. Jeitler, W. Kiesenhofer, A. Knapitsch, M. Krammer, D. Liko, I. Mikulec, M. Pernicka, B. Rahbaran, C. Rohringer, H. Rohringer, R. Schöfbeck, J. Strauss, A. Taurok, F. Teischinger, P. Wagner, W. Waltenberger, G. Walzel, E. Widl, C.-E. Wulz, V. Mossolov, N. Shumeiko, J. Suarez Gonzalez, S. Bansal, L. Benucci, T. Cornelis, E. A. De Wolf, X. Janssen, S. Luyckx, T. Maes, L. Mucibello, S. Ochesanu, B. Roland, R. Rougny, M. Selvaggi, H. Van Haevermaet, P. Van Mechelen, N. Van Remortel, A. Van Spilbeeck, F. Blekman, S. Blyweert, J. D’Hondt, R. Gonzalez Suarez, A. Kalogeropoulos, M. Maes, A. Olbrechts, W. Van Doninck, P. Van Mulders, G. P. Van Onsem, I. Villella, O. Charaf, B. Clerbaux, G. De Lentdecker, V. Dero, A. P. R. Gay, G. H. Hammad, T. Hreus, A. Léonard, P. E. 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Quan, A. Raval, H. Saka, D. Stickland, C. Tully, J. S. Werner, A. Zuranski, J. G. Acosta, X. T. Huang, A. Lopez, H. Mendez, S. Oliveros, J. E. Ramirez Vargas, A. Zatserklyaniy, E. Alagoz, V. E. Barnes, D. Benedetti, G. Bolla, L. Borrello, D. Bortoletto, M. De Mattia, A. Everett, L. Gutay, Z. Hu, M. Jones, O. Koybasi, M. Kress, A. T. Laasanen, N. Leonardo, V. Maroussov, P. Merkel, D. H. Miller, N. Neumeister, I. Shipsey, D. Silvers, A. Svyatkovskiy, M. Vidal Marono, H. D. Yoo, J. Zablocki, Y. Zheng, S. Guragain, N. Parashar, A. Adair, C. Boulahouache, V. Cuplov, K. M. Ecklund, F. J. M. Geurts, B. P. Padley, R. Redjimi, J. Roberts, J. Zabel, B. Betchart, A. Bodek, Y. S. Chung, R. Covarelli, P. de Barbaro, R. Demina, Y. Eshaq, A. Garcia-Bellido, P. Goldenzweig, Y. Gotra, J. Han, A. Harel, D. C. Miner, G. Petrillo, W. Sakumoto, D. Vishnevskiy, M. Zielinski, A. Bhatti, R. Ciesielski, L. Demortier, K. Goulianos, G. Lungu, C. Mesropian, S. Arora, O. Atramentov, A. Barker, J. P. Chou, C. Contreras-Campana, E. Contreras-Campana, D. Duggan, D. Ferencek, Y. Gershtein, R. Gray, E. Halkiadakis, D. Hidas, D. Hits, A. Lath, S. Panwalkar, R. Patel, A. Richards, K. Rose, S. Salur, S. Schnetzer, S. Somalwar, R. Stone, S. Thomas, G. Cerizza, M. Hollingsworth, S. Spanier, Z. C. Yang, A. York, R. Eusebi, W. Flanagan, J. Gilmore, T. Kamon, V. Khotilovich, R. Montalvo, I. Osipenkov, Y. Pakhotin, A. Perloff, J. Roe, A. Safonov, T. Sakuma, S. Sengupta, I. Suarez, A. Tatarinov, D. Toback, N. Akchurin, C. Bardak, J. Damgov, P. R. Dudero, C. Jeong, K. Kovitanggoon, S. W. Lee, T. Libeiro, P. Mane, Y. Roh, A. Sill, I. Volobouev, R. Wigmans, E. Yazgan, E. Appelt, E. Brownson, D. Engh, C. Florez, W. Gabella, A. Gurrola, M. Issah, W. Johns, C. Johnston, P. Kurt, C. Maguire, A. Melo, P. Sheldon, B. Snook, S. Tuo, J. Velkovska, M. W. Arenton, M. Balazs, S. Boutle, S. Conetti, B. Cox, B. Francis, S. Goadhouse, J. Goodell, R. Hirosky, A. Ledovskoy, C. Lin, C. Neu, J. Wood, R. Yohay, S. Gollapinni, R. Harr, P. E. Karchin, C. Kottachchi Kankanamge Don, P. Lamichhane, M. Mattson, C. Milstène, A. Sakharov, M. Anderson, M. Bachtis, D. Belknap, J. N. Bellinger, J. Bernardini, D. Carlsmith, M. Cepeda, S. Dasu, J. Efron, E. Friis, L. Gray, K. S. Grogg, M. Grothe, R. Hall-Wilton, M. Herndon, A. Hervé, P. Klabbers, J. Klukas, A. Lanaro, C. Lazaridis, J. Leonard, R. Loveless, A. Mohapatra, I. Ojalvo, G. A. Pierro, I. Ross, A. Savin, W. H. Smith, and J. Swanson
- Subjects
Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract Measurements from the CMS experiment at the LHC of dihadron correlations for charged particles produced in PbPb collisions at a nucleon–nucleon centre-of-mass energy of 2.76 TeV are presented. The results are reported as a function of the particle transverse momenta (p T) and collision centrality over a broad range in relative pseudorapidity (Δη) and the full range of relative azimuthal angle (Δϕ). The observed two-dimensional correlation structure in Δη and Δϕ is characterised by a narrow peak at (Δη,Δϕ)≈(0,0) from jet-like correlations and a long-range structure that persists up to at least |Δη|=4. An enhancement of the magnitude of the short-range jet peak is observed with increasing centrality, especially for particles of p T around 1–2 GeV/c. The long-range azimuthal dihadron correlations are extensively studied using a Fourier decomposition analysis. The extracted Fourier coefficients are found to factorise into a product of single-particle azimuthal anisotropies up to p T≈3–3.5 GeV/c for at least one particle from each pair, except for the second-order harmonics in the most central PbPb events. Various orders of the single-particle azimuthal anisotropy harmonics are extracted for associated particle p T of 1–3 GeV/c, as a function of the trigger particle p T up to 20 GeV/c and over the full centrality range.
- Published
- 2012
- Full Text
- View/download PDF
36. Effect of smokeless tobacco on the replication of herpes simplex virus in vitro and on production of viral lesions in hamster cheek pouch
- Author
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J.E. Stich, K.K. Li, R. Weiss, No-Hee Park, and Y.-S. Chun
- Subjects
DNA Replication ,Male ,Tobacco, Smokeless ,viruses ,Hamster ,medicine.disease_cause ,Virus Replication ,Tissue culture ,In vivo ,Cheek pouch ,Cricetinae ,Tobacco ,medicine ,Animals ,Simplexvirus ,General Dentistry ,Vero Cells ,biology ,Mesocricetus ,Plant Extracts ,Cell Biology ,General Medicine ,Cheek ,biology.organism_classification ,Virology ,Stomatitis, Herpetic ,Plants, Toxic ,medicine.anatomical_structure ,Herpes simplex virus ,Otorhinolaryngology ,Vero cell - Abstract
Previous experiments have shown that combination of herpes simplex virus (HSV) infection and simulated snuff-dipping in hamster buccal pouches enhances the development of micro-invasive squamous cell carcinoma in cheek pouch epithelium. The effect has now been determined of water-extractable components of snuff (snuff-extract) on the growth and the cell-lysing activity of HSV. Various dilutions of snuff-extract in tissue culture medium significantly inhibited the growth of HSV in Vero cell monolayers by inhibiting the viral DNA replication. Moreover, HSV was inactivated and its cell-lysing activity lost when it was incubated with snuff-extract in cell-free condition. Snuff also had a similar anti-herpetic effect in vivo; HSV infection of pouch tissues followed by simulated snuff-dipping resulted in significant inhibition of viral growth. Thus snuff interferes with the DNA synthesis and cytolytic activity of HSV in vitro and in vivo, and this in turn, may increase its oncogenic capacity.
- Published
- 1987
37. [Clinical considerations on the effect of the Wunderer activator for correction of anterior cross bite]
- Author
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Y S, Chun
- Subjects
Cephalometry ,Orthodontic Appliances, Removable ,Humans ,Activator Appliances ,Mandible ,Child ,Malocclusion - Published
- 1986
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