1,595 results on '"Y. Inagaki"'
Search Results
2. Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway
- Author
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Y. Sekii, H. Kiuchi, K. Takezawa, T. Imanaka, S. Kuribayashi, K. Okada, Y. Inagaki, N. Ueda, S. Fukuhara, R. Imamura, H. Negoro, and N. Nonomura
- Subjects
Biology (General) ,QH301-705.5 - Abstract
This study reports a mouse model of nocturnal polyuria - increased urine production at night that causes compromised quality of life and may impact mortality in older people. The authors identify a molecular pathway in the kidney that could prove to be a promising drug target for nocturnal polyuria.
- Published
- 2022
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3. Tadalafil and the efficacy on the post micturition dribble: Preliminary study
- Author
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H. Kiuchi, K. Okada, Y. Sekii, Y. Inagaki, K. Takezawa, S. Fukuhara, and N. Nonomura
- Subjects
Diseases of the genitourinary system. Urology ,RC870-923 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2020
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4. ESICM LIVES 2016: part one
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L. Bos, L. Schouten, L. van Vught, M. Wiewel, D. Ong, O. Cremer, A. Artigas, I. Martin-Loeches, A. Hoogendijk, T. van der Poll, J. Horn, N. Juffermans, M. Schultz, N. de Prost, T. Pham, G. Carteaux, A. Mekontso Dessap, C. Brun-Buisson, E. Fan, G. Bellani, J. Laffey, A. Mercat, L. Brochard, B. Maitre, LUNG SAFE investigators and the ESICM study group, P. A. Howells, D. R. Thickett, C. Knox, D. P. Park, F. Gao, O. Tucker, T. Whitehouse, D. F. McAuley, G. D. Perkins, LUNG SAFE Investigators and the ESICM Trials Group, L. Pisani, J. P. Roozeman, F. D. Simonis, A. Giangregorio, L. R. Schouten, S. M. Van der Hoeven, A. Serpa Neto, E. Festic, A. M. Dondorp, S. Grasso, L. D. Bos, M. J. Schultz, M. Koster-Brouwer, D. Verboom, B. Scicluna, K. van de Groep, J. Frencken, M. Bonten, J. I. Ko, K. S. Kim, G. J. Suh, W. Y. Kwon, K. Kim, J. H. Shin, O. T. Ranzani, E. Prina, R. Menendez, A. Ceccato, R. Mendez, C. Cilloniz, A. Gabarrus, M. Ferrer, A. Torres, A. Urbano, L. A. Zhang, D. Swigon, F. Pike, R. S. Parker, G. Clermont, C. Scheer, S. O. Kuhn, A. Modler, M. Vollmer, C. Fuchs, K. Hahnenkamp, S. Rehberg, M. Gründling, A. Taggu, N. Darang, N. Öveges, I. László, K. Tánczos, M. Németh, G. Lebák, B. Tudor, D. Érces, J. Kaszaki, W. Huber, D. Trásy, Z. Molnár, G. Ferrara, V. S. Kanoore Edul, H. S. Canales, E. Martins, C. Canullán, G. Murias, M. O. Pozo, J. F. Caminos Eguillor, M. G. Buscetti, C. Ince, A. Dubin, H. D. Aya, A. Rhodes, N. Fletcher, R. M. Grounds, M. Cecconi, M. Jacquet-Lagrèze, M. Riche, R. Schweizer, P. Portran, W. Fornier, M. Lilot, J. Neidecker, J. L. Fellahi, A. Escoresca-Ortega, A. Gutiérrez-Pizarraya, L. Charris-Castro, Y. Corcia-Palomo, E. Fernandez-Delgado, J. Garnacho-Montero, C. Roger, L. Muller, L. Elotmani, J. Lipman, J. Y. Lefrant, J. A. Roberts, R. Muñoz-Bermúdez, M. Samper, C. Climent, F. Vasco, V. Sara, S. Luque, N. Campillo, S. Grau Cerrato, J. R. Masclans, F. Alvarez-Lerma, S. Carvalho Brugger, G. Jimenez Jimenez, M. Miralbés Torner, J. Trujillano Cabello, B. Balsera Garrido, X. Nuvials Casals, F. Barcenilla Gaite, M. Vallverdú Vidal, M. Palomar Martínez, V. Gusarov, D. Shilkin, M. Dementienko, E. Nesterova, N. Lashenkova, A. Kuzovlev, M. Zamyatin, A. Demoule, S. Carreira, S. Lavault, O. Palancca, E. Morawiec, J. Mayaux, I. Arnulf, T. Similowski, B. S. Rasmussen, R. G. Maltesen, M. Hanifa, S. Pedersen, S. R. Kristensen, R. Wimmer, M. Panigada, G. Li Bassi, T. Kolobow, A. Zanella, M. Cressoni, L. Berra, V. Parrini, H. Kandil, G. Salati, S. Livigni, A. Amatu, A. Andreotti, F. Tagliaferri, G. Moise, G. Mercurio, A. Costa, A. Vezzani, S. Lindau, J. Babel, M. Cavana, D. Consonni, A. Pesenti, L. Gattinoni, for the GRAVITY-VAP TRIAL NETWORK, P. Mansouri, F. Zand, L. Zahed, F. Dehghanrad, M. Bahrani, M. Ghorbani, B. Cambiaghi, O. Moerer, T. Mauri, N. Kunze-Szikszay, C. Ritter, M. Quintel, L. M. Vilander, M. A. Kaunisto, S. T. Vaara, V. Pettilä, FINNAKI Study Group, J. L. G. Haitsma Mulier, S. Rozemeijer, A. M. E. Spoelstra-de Man, P. E. Elbers, P. R. Tuinman, M. C. de Waard, H. M. Oudemans-van Straaten, A. M. A. Liberatore, R. B. Souza, A. M. C. R. P. F. Martins, J. C. F. Vieira, I. H. J. Koh, M. Galindo Martínez, R. Jiménez Sánchez, L. Martínez Gascón, M. D. Rodríguez Mulero, A. Ortín Freire, A. Ojados Muñoz, S. Rebollo Acebes, Á. Fernández Martínez, S. Moreno Aliaga, L. Herrera Para, J. Murcia Payá, F. Rodríguez Mulero, P. Guerci, Y. Ince, P. Heeman, B. Ergin, Z. Uz, M. Massey, R. Papatella, E. Bulent, F. Toraman, E. R. Longbottom, H. D. Torrance, H. C. Owen, C. J. Hinds, R. M. Pearse, M. J. O’Dywer, Z. Trogrlic, M. van der Jagt, H. Lingsma, H. H. Ponssen, J. F. Schoonderbeek, F. Schreiner, S. J. Verbrugge, S. Duran, T. van Achterberg, J. Bakker, D. A. M. P. J. Gommers, E. Ista, A. Krajčová, P. Waldauf, F. Duška, A. Shah, N. Roy, S. McKechnie, C. Doree, S. Fisher, S. J. Stanworth, J. F. Jensen, D. Overgaard, M. H. Bestle, D. F. Christensen, I. Egerod, The RAPIT Group, A. Pivkina, I. Zhivotneva, N. Pasko, A. Alklit, R. L. Hansen, H. Knudsen, L. B. Grode, The RAPIT group, M. Hravnak, L. Chen, A. Dubrawski, M. R. Pinsky, S. M. Parry, L. D. Knight, B. C. Connolly, C. E. Baldwin, Z. A. Puthucheary, L. Denehy, N. Hart, P. E. Morris, J. Mortimore, C. L. Granger, H. I. Jensen, R. Piers, B. Van den Bulcke, J. Malmgren, V. Metaxa, A. K. Reyners, M. Darmon, K. Rusinova, D. Talmor, A. P. Meert, L. Cancelliere, L. Zubek, P. Maia, A. Michalsen, J. Decruyenaere, E. Kompanje, S. Vanheule, E. Azoulay, S. Vansteelandt, D. Benoit, C. Ryan, D. Dawson, J. Ball, K. Noone, B. Aisling, S. Prudden, A. Ntantana, D. Matamis, S. Savvidou, M. Giannakou, M. Gouva, G. Nakos, V. Koulouras, J. Aron, G. Lumley, D. Milliken, K. Dhadwal, B. A. McGrath, S. J. Lynch, B. Bovento, G. Sharpe, E. Grainger, S. Pieri-Davies, S. Wallace, B. McGrath, M. Jung, J. Cho, H. Park, G. Suh, O. Kousha, J. Paddle, L. Gamrin Gripenberg, M. Sundström Rehal, J. Wernerman, O. Rooyackers, H. J. de Grooth, W. P. Choo, A. M. Spoelstra-de Man, E. L. Swart, L. Talan, G. Güven, N. D. Altıntas, M. Padar, G. Uusvel, L. Starkopf, J. Starkopf, A. Reintam Blaser, M. S. Kalaiselvan, A. S. Arunkumar, M. K. Renuka, R. L. Shivkumar, M. Volbeda, D. ten Kate, M. Hoekstra, J. M. van der Maaten, M. W. Nijsten, A. Komaromi, Å. Norberg, M. Smedberg, M. Mori, L. Pettersson, M. Theodorakopoulou, T. Christodoulopoulou, A. Diamantakis, F. Frantzeskaki, M. Kontogiorgi, E. Chrysanthopoulou, M. Lygnos, C. Diakaki, A. Armaganidis, K. Gundogan, E. Dogan, R. Coskun, S. Muhtaroglu, M. Sungur, T. Ziegler, M. Guven, A. Kleyman, W. Khaliq, D. Andreas, M. Singer, R. Meierhans, R. Schuepbach, I. De Brito-Ashurst, G. Sabetian, R. Nikandish, F. Hagar, M. Masjedi, B. Maghsudi, A. Vazin, E. Asadpour, K. C. Kao, L. C. Chiu, C. Y. Hung, C. H. Chang, S. H. Li, H. C. Hu, S. El Maraghi, M. Ali, D. Rageb, M. Helmy, J. Marin-Corral, C. Vilà, A. Vàzquez, I. Martín-Loeches, E. Díaz, J. C. Yébenes, A. Rodriguez, F. Álvarez-Lerma, H1N1 SEMICYUC/GETGAG Working Group, N. Varga, A. Cortina-Gutiérrez, L. Dono, M. Martínez-Martínez, C. Maldonado, E. Papiol, M. Pérez-Carrasco, R. Ferrer, K. Nweze, B. Morton, I. Welters, M. Houard, B. Voisin, G. Ledoux, S. Six, E. Jaillette, S. Nseir, S. Romdhani, R. Bouneb, D. Loghmari, N. Ben Aicha, J. Ayachi, K. Meddeb, I. Chouchène, A. Khedher, M. Boussarsar, K. S. Chan, W. L. Yu, J. Nolla, L. Vidaur, J. Bonastre, B. Suberbiola, J. E. Guerrero, H1N1 SEMICYUC/GETGAG working group, N. Ramon Coll, G. Jiménez Jiménez, J. Codina Calero, M. García, M. C. de la Torre, E. Vendrell, E. Palomera, E. Güell, M. Serra-Prat, J. F. Bermejo-Martín, J. Almirall, E. Tomas, A. Escoval, F. Froe, M. H. Vitoria Pereira, N. Velez, E. Viegas, E. Filipe, C. Groves, M. Reay, A. Ballin, F. Facchin, G. Sartori, F. Zarantonello, E. Campello, C. M. Radu, S. Rossi, C. Ori, P. Simioni, N. Umei, I. Shingo, A. C. Santos, C. Candeias, I. Moniz, R. Marçal, Z. Costa e Silva, J. M. Ribeiro, J. F. Georger, J. P. Ponthus, M. Tchir, V. Amilien, M. Ayoub, E. Barsam, G. Martucci, G. Panarello, F. Tuzzolino, G. Capitanio, V. Ferrazza, T. Carollo, L. Giovanni, A. Arcadipane, M. López Sánchez, M. A. González-Gay, F. J. Llorca Díaz, M. I. Rubio López, E. Zogheib, L. Villeret, J. Nader, M. Bernasinski, P. Besserve, T. Caus, H. Dupont, P. Morimont, S. Habran, R. Hubert, T. Desaive, F. Blaffart, N. Janssen, J. Guiot, A. Pironet, P. Dauby, B. Lambermont, T. Pettenuzzo, G. Citton, C. Kirakli, O. Ediboglu, S. Ataman, M. Yarici, F. Tuksavul, S. Keating, A. Gibson, M. Gilles, M. Dunn, G. Price, N. Young, P. Remeta, P. Bishop, M. D. Fernández Zamora, J. Muñoz-Bono, E. Curiel-Balsera, E. Aguilar-Alonso, R. Hinojosa, A. Gordillo-Brenes, J. A. Arboleda-Sánchez, ARIAM-CARDIAC SURGERY PROJECT AUTHORS, I. Skorniakov, D. Vikulova, C. Whiteley, O. Shaikh, A. Jones, M. Ostermann, L. Forni, M. Scott, J. Sahatjian, W. Linde-Zwirble, D. Hansell, P. Laoveeravat, N. Srisawat, M. Kongwibulwut, S. Peerapornrattana, N. Suwachittanont, T. O. Wirotwan, P. Chatkaew, P. Saeyub, K. Latthaprecha, K. Tiranathanagul, S. Eiam-ong, J. A. Kellum, R. E. Berthelsen, A. Perner, A. E. K. Jensen, J. U. Jensen, D. J. Gebhard, J. Price, C. E. Kennedy, A. Akcan-Arikan, Y. R. Kang, M. N. Nakamae, K. Hamed, M. M. Khaled, R. Aly Soliman, M. Sherif Mokhtar, G. Seller-Pérez, D. Arias-Verdú, E. Llopar-Valdor, I. De-Diós-Chacón, G. Quesada-García, M. E. Herrera-Gutierrez, R. Hafes, G. Carroll, P. Doherty, C. Wright, I. G. Guerra Vera, M. Ralston, M. L. Gemmell, A. MacKay, E. Black, R. I. Docking, R. Appleton, M. R. Ralston, L. Gemmell, A. Mackay, J. G. Röttgering, P. W. G. Elbers, N. Mejeni, J. Nsiala, A. Kilembe, P. Akilimali, G. Thomas, A. E. Andersson, A. M. Fagerdahl, V. Knudsen, P-INFECT, A. Ben Cheikh, Y. Hamdaoui, A. Guiga, N. Fraj, N. Sma, I. Chouchene, N. Bouafia, A. Amirian, B. Ziaian, C. Fleischmann, D. O. Thomas-Rueddel, A. Schettler, D. Schwarzkopf, A. Stacke, K. Reinhart, A. Martins, P. Sousa, G. Snell, R. Matsa, T. T. S. Paary, A. M. Cavalheiro, L. L. Rocha, C. S. Vallone, A. Tonilo, M. D. S. Lobato, D. T. Malheiro, G. Sussumo, N. M. Lucino, V. D. Rosenthal, A. Sanaei Dashti, A. Yousefipour, J. R. Goodall, M. Williamson, E. Tant, N. Thomas, C. Balci, C. Gonen, E. Haftacı, H. Gurarda, E. Karaca, B. Paldusová, I. Zýková, D. Šímová, S. Houston, L. D’Antona, J. Lloyd, V. Garnelo-Rey, M. Sosic, V. Sotosek-Tokmazic, J. Kuharic, I. Antoncic, S. Dunatov, A. Sustic, C. T. Chong, M. Sim, T. Lyovarin, F. M. Acosta Díaz, S. Narbona Galdó, M. Muñoz Garach, O. Moreno Romero, A. M. Pérez Bailón, A. Carranza Pinel, M. Colmenero, A. Gritsan, A. Gazenkampf, E. Korchagin, N. Dovbish, R. M. Lee, M. P. P. Lim, B. C. L. Lim, J. J. See, R. Assis, F. Filipe, N. Lopes, L. Pessoa, T. Pereira, N. Catorze, M. S. Aydogan, C. Aldasoro, P. Marchio, A. Jorda, M. D. Mauricio, S. Guerra-Ojeda, M. Gimeno-Raga, M. Colque-Cano, A. Bertomeu-Artecero, M. Aldasoro, S. L. Valles, D. Tonon, T. Triglia, J. C. Martin, M. C. Alessi, N. Bruder, P. Garrigue, L. Velly, S. Spina, V. Scaravilli, C. Marzorati, E. Colombo, D. Savo, A. Vargiolu, G. Cavenaghi, G. Citerio, A. H. V. Andrade, P. Bulgarelli, J. A. P. Araujo, V. Gonzalez, V. A. Souza, C. Massant, C. A. C. Abreu Filho, R. A. Morbeck, L. E. Burgo, R. van Groenendael, L. T. van Eijk, G. P. Leijte, B. Koeneman, M. Kox, P. Pickkers, A. García-de la Torre, M. de la Torre-Prados, A. Fernández-Porcel, C. Rueda-Molina, P. Nuevo-Ortega, T. Tsvetanova-Spasova, E. Cámara-Sola, A. García-Alcántara, L. Salido-Díaz, X. Liao, T. Feng, J. Zhang, X. Cao, Q. Wu, Z. Xie, H. Li, Y. Kang, M. S. Winkler, A. Nierhaus, E. Mudersbach, A. Bauer, L. Robbe, C. Zahrte, E. Schwedhelm, S. Kluge, C. Zöllner, E. Mitsi, S. H. Pennington, J. Reine, A. D. Wright, R. Parker, I. D. Welters, J. D. Blakey, G. Rajam, E. W. Ades, D. M. Ferreira, D. Wang, A. Kadioglu, S. B. Gordon, R. Koch, J. Rahamat-Langedoen, J. Schloesser, M. de Jonge, J. Bringue, R. Guillamat-Prats, E. Torrents, M. L. Martinez, M. Camprubí-Rimblas, L. Blanch, S. Y. Park, Y. B. Park, D. K. Song, S. Shrestha, S. H. Park, Y. Koh, M. J. Park, C. W. Hong, O. Lesur, D. Coquerel, X. Sainsily, J. Cote, T. Söllradl, A. Murza, L. Dumont, R. Dumaine, M. Grandbois, P. Sarret, E. Marsault, D. Salvail, M. Auger-Messier, F. Chagnon, Apelin Group, M. P. Lauretta, E. Greco, A. Dyson, S. Preau, M. Ambler, A. Sigurta, S. Saeed, L. Topcu Sarıca, N. Zibandeh, D. Genc, F. Gul, T. Akkoc, E. Kombak, L. Cinel, I. Cinel, S. J. Pollen, N. Arulkumaran, G. Warnes, D. J. Pennington, K. Brohi, M. J. O’Dwyer, H. Y. Kim, S. Na, J. Kim, Y. F. Chang, A. Chao, P. Y. Shih, C. T. Lee, Y. C. Yeh, L. W. Chen, M. Adriaanse, W. Rietdijk, S. Funcke, S. Sauerlaender, B. Saugel, H. Pinnschmidt, D. A. Reuter, R. Nitzschke, S. Perbet, C. Biboulet, A. Lenoire, D. Bourdeaux, B. Pereira, B. Plaud, J. E. Bazin, V. Sautou, A. Mebazaa, J. M. Constantin, M. Legrand, Y. Boyko, P. Jennum, M. Nikolic, H. Oerding, R. Holst, P. Toft, H. K. Nedergaard, T. Haberlandt, S. Park, S. Kim, Y. J. Cho, Y. J. Lim, A. Chan, S. Tang, S. L. Nunes, S. Forsberg, H. Blomqvist, L. Berggren, M. Sörberg, T. Sarapohja, C. J. Wickerts, J. G. M. Hofhuis, L. Rose, B. Blackwood, E. Akerman, J. Mcgaughey, M. Fossum, H. Foss, E. Georgiou, H. J. Graff, M. Kalafati, R. Sperlinga, A. Schafer, A. G. Wojnicka, P. E. Spronk, F. Khalili, R. Afshari, H. Haddad Khodaei, S. Javadpour, P. Petramfar, S. Nasimi, H. Tabei, A. Gunther, J. O. Hansen, P. Sackey, H. Storm, J. Bernhardsson, Ø. Sundin, A. Bjärtå, A. Bienert, P. Smuszkiewicz, P. Wiczling, K. Przybylowski, A. Borsuk, I. Trojanowska, J. Matysiak, Z. Kokot, M. Paterska, E. Grzeskowiak, A. Messina, E. Bonicolini, D. Colombo, G. Moro, S. Romagnoli, A. R. De Gaudio, F. Della Corte, S. M. Romano, J. A. Silversides, E. Major, E. E. Mann, A. J. Ferguson, D. F. Mcauley, J. C. Marshall, J. A. Diaz-Rodriguez, R. Silva-Medina, E. Gomez-Sandoval, N. Gomez-Gonzalez, R. Soriano-Orozco, P. L. Gonzalez-Carrillo, M. Hernández-Flores, K. Pilarczyk, J. Lubarksi, D. Wendt, F. Dusse, J. Günter, B. Huschens, E. Demircioglu, H. Jakob, A. Palmaccio, A. M. Dell’Anna, D. L. Grieco, F. Torrini, C. Iaquaniello, F. Bongiovanni, M. Antonelli, L. Toscani, D. Antonakaki, D. Bastoni, M. Jozwiak, F. Depret, J. L. Teboul, J. Alphonsine, C. Lai, C. Richard, X. Monnet, G. Demeter, I. Kertmegi, A. Hasanin, A. Lotfy, A. El-adawy, H. Nassar, S. Mahmoud, A. Abougabal, A. Mukhtar, F. Quinty, S. Habchi, A. Luzi, E. Antok, G. Hernandez, B. Lara, L. Enberg, M. Ortega, P. Leon, C. Kripper, P. Aguilera, E. Kattan, M. Lehmann, S. Sakka, B. Bein, R. M. Schmid, J. Preti, J. Creteur, A. Herpain, J. Marc, F. Trojette, S. Bar, L. Kontar, D. Titeca, J. Richecoeur, B. Gelee, N. Verrier, R. Mercier, E. Lorne, J. Maizel, M. Slama, M. E. Abdelfattah, A. Eladawy, M. A. Ali Elsayed, A. Pedraza Montenegro, E. Monares Zepeda, J. Franco Granillo, J. S. Aguirre Sánchez, G. Camarena Alejo, A. Rugerio Cabrera, A. A. Tanaka Montoya, C. Lee, F. Hatib, M. Cannesson, P. Theerawit, T. Morasert, Y. Sutherasan, G. Zani, S. Mescolini, M. Diamanti, R. Righetti, A. Scaramuzza, M. Papetti, M. Terenzoni, C. Gecele, M. Fusari, K. A. Hakim, A. Chaari, M. Ismail, A. H. Elsaka, T. M. Mahmoud, K. Bousselmi, V. Kauts, W. F. Casey, S. D. Hutchings, D. Naumann, J. Wendon, S. Watts, E. Kirkman, Z. Jian, S. Buddi, J. Settels, P. Bertini, F. Guarracino, C. Trepte, P. Richter, S. A. Haas, V. Eichhorn, J. C. Kubitz, M. S. Soliman, W. I. Hamimy, A. Z. Fouad, A. M. Mukhtar, M. Charlton, L. Tonks, L. Mclelland, T. J. Coats, J. P. Thompson, M. R. Sims, D. Williams, D. Z. Roushdy, R. A. Soliman, R. A. Nahas, M. Y. Arafa, W. T. Hung, C. C. Chiang, W. C. Huang, K. C. Lin, S. C. Lin, C. C. Cheng, P. L. Kang, S. R. Wann, G. Y. Mar, C. P. Liu, M. Lopez Carranza, H. Sancho Fernandez, J. A. Sanchez Roman, F. Lucena, A. Campanario Garcia, A. Loza Vazquez, A. Lesmes Serrano, ARIAM-SEMICYUC Registry Investigators, L. Sayagues Moreira, R. Vidal-Perez, U. Anido Herranz, J. M. Garcia Acuna, C. Pena Gil, J. L. Garcia Allut, P. Rascado Sedes, C. Martin Lopez, E. Saborido Paz, C. Galban Rodriguez, J. R. Gonzalez-Juanatey, A. Vallejo-Baez, M. V. de la Torre-Prados, ARIAM Group, R. Marharaj, K. Gervasio, M. Bottiroli, M. Mondino, D. De Caria, A. Calini, E. Montrasio, F. Milazzo, M. P. Gagliardone, A. Vallejo-Báez, ARIAM group, U. Anido, M. Cheikh-Bouhlel, M. P. R. D. L. Dela Cruz, J. M. Bernardo, F. Galfo, A. Marino, C. C. Chao, P. Hou, C. C. Hung, C. H. Chiang, Y. J. Liou, S. M. Hung, Y. S. Lin, F. Y. Kuo, K. R. Chiou, C. J. Chen, L. S. Yan, C. Y. Liu, H. H. Wang, H. L. Chen, C. K. Ho, S. Grewal, S. Gopal, C. Corbett, A. Wilson, J. Capps, W. Ayoub, A. Lomas, S. Ghani, J. Moore, D. Atkinson, M. Sharman, W. Swinnen, J. Pauwels, K. Mignolet, E. Pannier, A. Koch, T. Sarens, W. Temmerman, A. M. Elmenshawy, A. M. Fayed, M. Elboriuny, E. Hamdy, E. Zakaria, A. C. Falk, A. Petosic, K. Olafsen, H. Wøien, H. Flaatten, K. Sunde, J. J. Cáceres Agra, J. L. Santana Cabrera, J. D. Martín Santana, L. Melián Alzola, H. Rodríguez Pérez, T. Castro Pires, H. Calderón, A. Pereira, S. Castro, C. Granja, I. Norkiene, I. Urbanaviciute, G. Kezyte, D. Ringaitiene, T. Jovaisa, G. Vogel, U. B. Johansson, A. Sandgren, C. Svensen, E. Joelsson-Alm, M. A. Leite, L. D. Murbach, E. F. Osaku, C. R. L. M. Costa, M. Pelenz, N. M. Neitzke, M. M. Moraes, J. L. Jaskowiak, M. M. M. Silva, R. S. Zaponi, L. R. L. Abentroth, S. M. Ogasawara, A. C. Jorge, P. A. D. Duarte, J. Barreto, S. T. Duarte, S. Taba, D. Miglioranza, D. P. Gund, C. F. Lordani, H. Vollmer, M. Gager, C. Waldmann, A. T. Mazzeo, R. Tesio, C. Filippini, M. E. Vallero, C. Giolitti, S. Caccia, M. Medugno, T. Tenaglia, R. Rosato, I. Mastromauro, L. Brazzi, P. P. Terragni, R. Urbino, V. Fanelli, V. M. Ranieri, L. Mascia, J. Ballantyne, L. Paton, P. Perez-Teran, O. Roca, J. C. Ruiz-Rodriguez, A. Zapatero, J. Serra, S. Bianzina, P. Cornara, G. Rodi, G. Tavazzi, M. Pozzi, G. A. Iotti, F. Mojoli, A. Braschi, A. Vishnu, D. Buche, R. Pande, D. L. J. Moolenaar, F. Bakhshi-Raiez, D. A. Dongelmans, N. F. de Keizer, D. W. de Lange, I. Fuentes Fernández, D. Martínez Baño, J. L. Buendía Moreno, R. Jara Rubio, J. Scott, D. Phelan, D. Morely, J. O’Flynn, P. Stapleton, M. Lynch, B. Marsh, E. Carton, C. O’Loughlin, K. C. Cheng, M. I. Sung, M. O. Elghonemi, M. H. Saleh, T. S. Meyhoff, M. Krag, P. B. Hjortrup, M. H. Møller, T. Öhman, T. Sigmundsson, E. Redondo, M. Hallbäck, F. Suarez-Sipmann, H. Björne, C. Hällsjö Sander, KARISMA, D. Chiumello, C. Chiurazzi, M. Brioni, I. Algieri, M. Guanziroli, G. Vergani, T. Tonetti, I. Tomic, A. Colombo, F. Crimella, E. Carlesso, V. Gasparovic, R. El-Sherif, M. Abd Al-Basser, A. Raafat, A. El-Sherif, L. R. A. Schouten, O. L. Cremer, D. S. Y. Ong, G. Amoruso, G. Cinnella, L. D. J. Bos, P. Schmidle, M. Findeisen, P. Hoppmann, J. Jaitner, F. Brettner, T. Lahmer, EXODUS-investigators, G. Rajagopalan, V. Bansal, R. Frank, R. Hinds, J. Levitt, United States Critical Illness and Injury Trials Group/LIPS-B investigators, S. Siddiqui, SICM NICER Group, J. P. Gilbert, K. Sim, C. H. Wang, I. J. Li, W. R. Tang, P. Persona, A. De Cassai, M. Franco, A. Goffi, B. Llorente Ruiz, J. Lujan Varas, R. Molina Montero, C. Pintado Delgado, O. Navarrete, M. Vazquez Mezquita, E. Alonso Peces, M. A. M. Nakamura, L. A. Hajjar, F. R. B. G. Galas, T. A. Ortiz, M. B. P. Amato, L. Bitker, N. Costes, D. Le Bars, F. Lavenne, D. Mojgan, J. C. Richard, D. Massari, M. Gotti, P. Cadringher, A. Zerman, M. Türkoğlu, G. Arık, F. Yıldırım, Z. Güllü, I. Kara, N. Boyacı, B. Basarık Aydoğan, Ü. Gaygısız, K. Gönderen, G. Aygencel, M. Aydoğdu, Z. Ülger, G. Gürsel, J. Riera, C. Maldonado Toral, C. Mazo, M. Martínez, J. Baldirà, L. Lagunes, A. Roman, M. Deu, J. Rello, D. J. Levine, R. M. Mohus, Å. Askim, J. Paulsen, A. Mehl, A. T. Dewan, J. K. Damås, E. Solligård, B. O. Åsvold, Mid-Norway Sepsis Research Center, A. DeWan, O. Aktepe, A. Kara, H. Yeter, A. Topeli, M. Norrenberg, M. Devroey, H. Khader, J. C. Preiser, Z. Tang, C. Qiu, L. Tong, C. Cai, O. Apostolopoulou, J. Y. Moon, M. R. Park, I. S. Kwon, G. R. Chon, J. Y. Ahn, S. J. Kwon, Y. J. Chang, J. Y. Lee, S. Y. Yoon, J. W. Lee, The Korean Chungcheong Critical Care Research Group, M. Kostalas, J. Mckinlay, G. Kooner, G. Dudas, A. Horton, C. Kerr, N. Karanjia, B. Creagh-Brown, N. D. Altintas, S. Izdes, O. Keremoglu, A. Alkan, S. Neselioglu, O. Erel, N. Tardif, T. Gustafsson, K. N. MacEachern, M. Traille, I. Bromberg, S. E. Lapinsky, M. J. Moore, J. L. García-Garmendia, F. Villarrasa-Clemente, F. Maroto-Monserrat, O. Rufo-Tejeiro, V. Jorge-Amigo, M. Sánchez-Santamaría, C. Colón-Pallarés, A. Barrero-Almodóvar, S. Gallego-Lara, C. T. Anthon, R. B. Müller, N. Haase, K. Møller, J. Wetterslev, M. Nakanishi, A. Kuriyama, T. Fukuoka, M. A. Abd el Halim, M. H. Elsaid hafez, A. M. Moktar, H. M. Elazizy, K. Abdel Hakim, M. Elbahr, T. Mahmoud, E. Khalil, W. Casey, S. H. Zaky, A. Rizk, R. Ahmed, G. A. Ospina-Tascón, A. F. Garcia Marin, G. J. Echeverry, W. F. Bermudez, H. J. Madriñan-Navia, J. D. Valencia, E. Quiñonez, A. Marulanda, C. A. Arango-Dávila, A. Bruhn, D. De Backer, D. Orbegozo Cortes, F. Su, J. L. Vincent, L. Tullo, L. Mirabella, P. Di Molfetta, M. Dambrosio, C. Villavicencio Lujan, J. Leache irigoyen, M. Cartanya ferré, R. Carbonell García, M. Ahmed, M. El Ayashi, E. Ayman, M. Salem, S. Fathy, A. Zaghlol, M. F. Aguilar Arzapalo, Å. Valsø, T. Rustøen, I. Schou-Bredal, L. Skogstad, K. Tøien, C. Padilla, Y. Palmeiro, W. Egbaria, R. Kigli, B. Maertens, K. Blot, S. Blot, E. Santana-Santos, E. R. dos Santos, R. E. D. L. Ferretti-Rebustini, R. D. C. C. D. O. dos Santos, R. G. S. Verardino, L. A. Bortolotto, A. M. Doyle, I. Naldrett, J. Tillman, S. Price, P. Pearson, J. Greaves, D. Goodall, A. Berry, A. Richardson, G. O. Odundo, P. Omengo, P. Obonyo, N. M. Chanzu, R. Kleinpell, S. J. Sarris, P. Nedved, M. Heitschmidt, H. Ben-Ghezala, S. Snouda, S. Djobbi, N. K. J. Adhikari, D. Leasa, D. Fergusson, D. A. Mckim, J. Weblin, D. McWilliams, F. Doesburg, F. Cnossen, W. Dieperink, W. Bult, M. W. N. Nijsten, G. A. Galvez-Blanco, C. I. Olvera Guzman, J. Santos Stroud, R. Thomson, M. Llaurado-Serra, A. Lobo-Civico, M. Pi-Guerrero, I. Blanco-Sanchez, A. Piñol-Tena, C. Paños-Espinosa, Y. Alabart-Segura, B. Coloma-Gomez, A. Fernandez-Blanco, F. Braga-Dias, M. Treso-Geira, A. Valeiras-Valero, L. Martinez-Reyes, A. Sandiumenge, M. F. Jimenez-Herrera, CAPCRI Study, R. Prada, P. Juárez, R. Argandoña, J. J. Díaz, C. Sánchez Ramirez, P. Saavedra, S. Ruiz Santana, O. Obukhova, S. Kashiya, I. A. Kurmukov, A. M. Pronina, P. Simeone, L. Puybasset, G. Auzias, O. Coulon, B. Lesimple, G. Torkomian, A. Bartkowska-Sniatkowska, O. Szerkus, D. Siluk, J. Bartkowiak-Wieczorek, J. Rosada-Kurasinska, J. Warzybok, R. Kaliszan, C. Hernandez Caballero, S. Roberts, G. Isgro, D. Hall, G. Guillaume, O. Passouant, F. Dumas, W. Bougouin, B. Champigneulle, M. Arnaout, J. Chelly, J. D. Chiche, O. Varenne, J. P. Mira, E. Marijon, A. Cariou, M. Beerepoot, H. R. Touw, K. Parlevliet, C. Boer, P. W. Elbers, Á. J. Roldán Reina, Y. Corcia Palomo, R. Martín Bermúdez, L. Martín Villén, I. Palacios García, J. R. Naranjo Izurieta, J. B. Pérez Bernal, F. J. Jiménez Jiménez, Cardiac Arrest Group HUVR, F. Cota-Delgado, T. Kaneko, H. Tanaka, M. Kamikawa, R. Karashima, S. Iwashita, H. Irie, S. Kasaoka, O. Arola, R. Laitio, A. Saraste, J. Airaksinen, M. Pietilä, M. Hynninen, J. Wennervirta, M. Bäcklund, E. Ylikoski, P. Silvasti, E. Nukarinen, J. Grönlund, V. P. Harjola, J. Niiranen, K. Korpi, M. Varpula, R. O. Roine, T. Laitio, for the Xe-HYPOTHECA study group, S. Salah, B. G. Hassen, A. Mohamed Fehmi, Y. C. Hsu, J. Barea-Mendoza, C. García-Fuentes, M. Castillo-Jaramillo, H. Dominguez-Aguado, R. Viejo-Moreno, L. Terceros-Almanza, S. Bermejo Aznárez, C. Mudarra-Reche, W. Xu, M. Chico-Fernández, J. C. Montejo-González, K. Crewdson, M. Thomas, M. Merghani, L. Fenner, P. Morgan, D. Lockey, E. J. van Lieshout, B. Oomen, J. M. Binnekade, R. J. de Haan, N. P. Juffermans, M. B. Vroom, R. Algarte, L. Martínez, B. Sánchez, I. Romero, F. Martínez, S. Quintana, J. Trenado, O. Sheikh, D. Pogson, R. Clinton, F. Riccio, A. Arthur, L. Young, A. Sinclair, D. Markopoulou, K. Venetsanou, L. Filippou, E. Salla, S. Stratouli, I. Alamanos, A. H. Guirgis, R. Gutiérrez Rodriguez, M. J. Furones Lorente, I. Macias Guarasa, A. Ukere, S. Meisner, G. Greiwe, B. Opitz, D. Benten, B. Nashan, L. Fischer, C. J. C. Trepte, C. R. Behem, B. Ana, A. Vazir, D. Gibson, M. R. Hadavi, M. Riahi alam, M. R. Sasani, N. Parenti, F. Agrusta, C. Palazzi, B. Pifferi, R. Sganzerla, F. Tagliazucchi, A. Luciani, M. Möller, J. Müller-Engelmann, G. Montag, P. Adams, C. Lange, J. Neuzner, R. Gradaus, K. H. Wodack, F. Thürk, A. D. Waldmann, M. F. Grässler, S. Nishimoto, S. H. Böhm, E. Kaniusas, C. J. Trepte, M. Wallin, F. Suarez Sipman, A. Oldner, L. Colinas, R. Vicho, M. Serna, R. Cuena, A. Canabal, ECOCRITIC group, M. Etman, M. El Bahr, A. El Sakka, A. Arali, O. Bond, P. De Santis, E. Iesu, F. Franchi, S. Scolletta, F. S. Taccone, Z. Marutyan, L. Hamidova, A. Shakotko, V. Movsisyan, I. Uysupova, A. Evdokimov, S. Petrikov, F. J. Redondo Calvo, N. Bejarano, V. Baladron, R. Villazala, J. Redondo, D. Padilla, P. Villarejo, C. Gomez-Gonzalez, S. Mas-Font, A. Puppo-Moreno, M. Herrera-Gutierrez, M. Garcia-Garcia, S. Aldunate-Calvo, NEFROCON Investigators, E. P. Plata-Menchaca, X. L. Pérez-Fernández, M. Estruch, A. Betbese-Roig, P. Cárdenas Campos, M. Rojas Lora, N. D. Toapanta Gaibor, R. S. Contreras Medina, V. D. Gumucio Sanguino, E. J. Casanova, J. Sabater Riera, SIRAKI group, K. Kritmetapak, S. Peerapornratana, P. Kittiskulnam, T. Dissayabutra, P. Susantithapong, K. Praditpornsilpa, K. Tungsanga, S. Eiam-Ong, T. Winkelmann, T. Busch, J. Meixensberger, S. Bercker, E. M. Flores Cabeza, M. Sánchez Sánchez, N. Cáceres Giménez, C. Gutierrez Melón, E. Herrero de Lucas, P. Millán Estañ, M. Hernández Bernal, A. Garcia de Lorenzo y Mateos, P. A. C. Specht, M. Balik, M. Zakharchenko, F. Los, H. Brodska, C. de Tymowski, P. Augustin, M. Desmard, P. Montravers, S. N. Stapel, R. de Boer, H. M. Oudemans, A. Hollinger, T. Schweingruber, F. Jockers, M. Dickenmann, M. Siegemund, Clinical Intensive Care Research Basel, N. Runciman, L. Alban, C. Turrini, T. Sasso, T. Langer, P. Taccone, C. Marenghi, G. Grasselli, P. Wibart, T. Reginault, M. Garcia, B. Barbrel, A. Benard, C. Bader, F. Vargas, H. N. Bui, G. Hilbert, J. M. Serrano Simón, P. Carmona Sánchez, F. Ruiz Ferrón, M. García de Acilu, J. Marin, V. Antonia, L. Ruano, M. Monica, G. Hong, D. H. Kim, Y. S. Kim, J. S. Park, Y. K. Jee, Z. Yu xiang, W. Jia-xing, W. Xiao dan, N. Wen long, W. Yu, Z. Yan, X. Cheng, T. Kobayashi, Y. Onodera, R. Akimoto, A. Sugiura, H. Suzuki, M. Iwabuchi, M. Nakane, K. Kawamae, P. Carmona Sanchez, M. D. Bautista Rodriguez, M. Rodriguez Delgado, V. Martínez de Pinillos Sánchez, A. Mula Gómez, P. Beuret, C. Fortes, M. Lauer, M. Reboul, J. C. Chakarian, X. Fabre, B. Philippon-Jouve, S. Devillez, M. Clerc, N. Rittayamai, M. Sklar, M. Dres, M. Rauseo, C. Campbell, B. West, D. E. Tullis, M. Okada, N. Ahmad, M. Wood, A. Glossop, J. Higuera Lucas, A. Blandino Ortiz, D. Cabestrero Alonso, R. De Pablo Sánchez, L. Rey González, R. Costa, G. Spinazzola, A. Pizza, G. Ferrone, M. Rossi, G. Conti, H. Ribeiro, J. Alves, M. Sousa, P. Reis, C. S. Socolovsky, R. P. Cauley, J. E. Frankel, A. L. Beam, K. O. Olaniran, F. K. Gibbons, K. B. Christopher, J. Pennington, P. Zolfaghari, H. S. King, H. H. Y. Kong, H. P. Shum, W. W. Yan, C. Kaymak, N. Okumus, A. Sari, B. Erdogdu, S. Aksun, H. Basar, A. Ozcan, N. Ozcan, D. Oztuna, J. A. Malmgren, S. Lundin, K. Torén, M. Eckerström, A. Wallin, A. C. Waldenström, for the Section on Ethics of the ESICM, F. C. Riccio, A. C. P. Antonio, A. F. Leivas, F. Kenji, E. James, S. Jonnada, C. S. Gerrard, N. Jones, J. D. Salciccioli, D. C. Marshall, M. Komorowski, A. Hartley, M. C. Sykes, R. Goodson, J. Shalhoub, J. R. Fernández Villanueva, R. Fernández Garda, A. M. López Lago, E. Rodríguez Ruiz, R. Hernández Vaquero, C. Galbán Rodríguez, E. Varo Pérez, C. Hilasque, I. Oliva, G. Sirgo, M. C. Martin, M. Olona, M. C. Gilavert, M. Bodí, C. Ebm, G. Aggarwal, S. Huddart, N. Quiney, S. M. Fernandes, J. Santos Silva, J. Gouveia, D. Silva, R. Marques, H. Bento, A. Alvarez, Z. Costa Silva, D. Díaz Diaz, M. Villanova Martínez, E. Palencia Herrejon, A. Martinez de la Gandara, G. Gonzalo, M. A. Lopez, P. Ruíz de Gopegui Miguelena, C. I. Bernal Matilla, P. Sánchez Chueca, M. D. C. Rodríguez Longares, R. Ramos Abril, A. L. Ruíz Aguilar, R. Garrido López de Murillas, R. Fernández Fernández, P. Morales Laborías, M. A. Díaz Castellanos, M. E. Morales Laborías, J. Park, S. Woo, T. West, E. Powell, A. Rimmer, C. Orford, J. Williams, P. Ruiz de Gopegui Miguelena, R. S. Bourne, R. Shulman, M. Tomlin, G. H. Mills, M. Borthwick, W. Berry, D. García Huertas, F. Manzano, F. Villagrán-Ramírez, A. Ruiz-Perea, C. Rodríguez-Mejías, F. Santiago-Ruiz, M. Colmenero-Ruiz, C. König, B. Matt, A. Kortgen, C. S. Hartog, A. Wong, C. Balan, G. Barker, S. Tachaboon, J. Paratz, G. Kayambu, R. Boots, R. Vlasenko, E. Gromova, S. Loginov, M. Kiselevskiy, Y. Dolgikova, K. B. Tang, C. M. Chau, K. N. Lam, E. Gil, G. Y. Suh, C. M. Park, C. R. Chung, C. H. Lai, Y. J. Cheng, V. Colella, N. Zarrillo, M. D’Amico, F. Forfori, B. Pezza, T. Laddomada, V. Beltramelli, M. L. Pizzaballa, A. Doronzio, B. Balicco, D. Kiers, W. van der Heijden, J. Gerretsen, Q. de Mast, S. el Messaoudi, G. Rongen, M. Gomes, N. P. Riksen, Y. Kashiwagi, K. Hayashi, Y. Inagaki, S. Fujita, A. Blet, M. Sadoune, J. Lemarié, N. Bihry, R. Bern, E. Polidano, R. Merval, J. M. Launay, B. Lévy, J. L. Samuel, J. Hartmann, S. Harm, and V. Weber
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Published
- 2016
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5. Reopening of ductus arteriosus in idiopathic premature constriction or closure of ductus arteriosus: A case series
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H. Aoki, M. Kawataki, K. Kim, T. Saito, Y. Inagaki, T. Shimokaze, H. Ishikawa, and K. Toyoshima
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Pediatrics, Perinatology and Child Health - Abstract
BACKGROUND: There is no consensus on managing pregnancy when the fetus is diagnosed with idiopathic premature constriction or closure of the ductus arteriosus (PCDA). Knowing whether the ductus reopens is valuable information for managing idiopathic PCDA. We conducted a case-series study to investigate the natural perinatal course of idiopathic PCDA and examined factors associated with ductal reopening. METHODS: We retrospectively collected information about the perinatal course and echocardiographic findings at our institution, which, on principle, does not determine delivery timing based on fetal echocardiographic results. We also examined perinatal factors related to the reopening of the ductus arteriosus. RESULTS: Thirteen cases of idiopathic PCDA were included in the analysis. The ductus reopened in 38% of cases. Among cases diagnosed in
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- 2023
6. The structure of fish follower-feeding associations at three oceanic islands in southwestern Atlantic
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Mauricio Cantor, Ivan Sazima, Kelly Y. Inagaki, Juan P. Quimbayo, Thiago C. Mendes, and UNIVERSIDADE ESTADUAL DE CAMPINAS
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0106 biological sciences ,Foraging ,Aquatic Science ,Biology ,010603 evolutionary biology ,01 natural sciences ,PEIXES ,Fishes - Feeding and feeds ,Artigo original ,Brazilian province ,Reef ,Ecological interactions ,Ecology, Evolution, Behavior and Systematics ,Trophic level ,geography ,geography.geographical_feature_category ,Ecology ,Peixe - Alimentação e rações ,010604 marine biology & hydrobiology ,Substrate (marine biology) ,Commensalism ,Habitat ,Nuclear-follower associations ,%22">Fish ,Interações ecológicas ,Omnivore ,Species richness - Abstract
Agradecimentos: This study was part of the research program "Programa de Monitoramento de Longa Duração das Comunidades Recifais de Ilhas Oceânicas - PELD" (441241/2016-6, Carlos E.L. Ferreira-PI). K.Y.I. received scholarships from Coordination for the Improvement of Higher Education Personnel (CAPES) - Finance Code 001 - and Brazilian National Council for Scientific and Technological Development (CNPq); T.C.M. received post-doctoral fellowship from Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ; E-26/202.858/2016); J.P.Q. received post-doctoral fellowship from FAPESP (2018/21380-0); M.C. received post-doctoral fellowships from CNPq (153797/2016-9), Projeto Monitoramento de Praias (PMP/BS UFPR/UNIVALI 46/2016) and CAPES (PDE 88881.170254/2018-01); I.S. received grants from CNPq. We thank J.P. Krajewski, C. Sazima, and L. Almeida for the photographs of reef fish follower-feeding associations, and two anonymous referees for insightful suggestions. J.P.Q. thanks for the contribution of the Research Center for Marine Biodiversity of the University of São Paulo (NPBiomar) Abstract: Structurally complex and competitive environments such as reef habitats may promote alternative behavioural feeding tactics in fishes. An understudied behavioural tactic is the follower-feeding association, in which individuals of a species follow (called "follower") and benefit from the foraging activities of individuals of another species that disturbs the substrate (called "nuclear"). Here, we investigated the incidence of this tactic at three oceanic islands in the southwestern Atlantic by characterizing pairwise, and the emergent network of follower-feeding associations. We quantified associations among species according to their trophic categories, activity period, and group size. The incidence of follower-feeding associations was higher at islands with higher species richness, but the proportion of associations per species was higher at islands with lower species richness. Overall, mobile invertebrate-feeders, omnivores and macrocarnivores were the most common trophic categories engaged in this tactic. Most of follower-feeding associations involved diurnal species, which indicates that followers rely on visual cues to engage in this tactic. We also found that nuclear species were mainly solitary, while followers tended to aggregate in small- to medium-sized groups. Our study indicates that follower-feeding association is an opportunistic yet frequent feeding tactic at oceanic islands, which may stem from resource partitioning in such remote habitats CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP Fechado
- Published
- 2019
7. Trophic interactions will expand geographically, but be less intense as oceans warm
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Maria Grazia Pennino, Mark E. Hay, Sergio R. Floeter, Kelly Y. Inagaki, and Guilherme O. Longo
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0106 biological sciences ,latitudinal patterns ,010504 meteorology & atmospheric sciences ,Coral reef fish ,Climate Change ,Oceans and Seas ,Effects of global warming on oceans ,Western Atlantic ,Climate change ,010603 evolutionary biology ,01 natural sciences ,Animals ,Environmental Chemistry ,Dominance (ecology) ,Ecosystem ,Pesquerías ,Centro Oceanográfico de Murcia ,climate ,Bayesian models ,0105 earth and related environmental sciences ,General Environmental Science ,Trophic level ,biodiversity ,fish ,Global and Planetary Change ,Biomass (ecology) ,Ecology ,tropicalization ,prediction ,Caribbean Region ,feeding pressure ,Ectotherm ,Environmental science ,future projections ,ecosystems ,Brazil - Abstract
Interactions among species are likely to change geographically due to climate-driven species range shifts and in intensity due to physiological responses to increasing temperatures. Marine ectotherms experience temperatures closer to their upper thermal limits due to the paucity of temporary thermal refugia compared to those available to terrestrial organisms. Thermal limits of marine ectotherms also vary among species and trophic levels, making their trophic interactions more prone to changes as oceans warm. We assessed how temperature affects reef fish trophic interactions in the Western Atlantic and modeled projections of changes in fish occurrence, biomass, and feeding intensity across latitudes due to climate change. Under ocean warming, tropical reefs will experience diminished trophic interactions, particularly herbivory and invertivory, potentially reinforcing algal dominance in this region. Tropicalization events are more likely to occur in the northern hemisphere, where feeding by tropical herbivores is predicted to expand from the northern Caribbean to extratropical reefs. Conversely, feeding by omnivores is predicted to decrease in this area with minor increases in the Caribbean and southern Brazil. Feeding by invertivores declines across all latitudes in future predictions, jeopardizing a critical trophic link. Most changes are predicted to occur by 2050 and can significantly affect ecosystem functioning, causing dominance shifts and the rise of novel ecosystems., SI
- Published
- 2021
8. The marine ornamental market in Brazil (Southwestern Atlantic) frequently trades prohibited and endangered species, and threatens the ecosystem role of cleaning mutualism
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Laila M. Carvalho, Miguel Mies, Kelly Y. Inagaki, Eduardo G. Sanches, Marcelo R. Souza, Guilherme O. Longo, and Acácio R.G. Tomás
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Economics and Econometrics ,Management, Monitoring, Policy and Law ,Aquatic Science ,Law ,General Environmental Science - Published
- 2022
9. The clinical outcome of fractional flow reserve based coronary revascularization strategy of the patients on hemodialysis
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K Hirobe, H Otsuki, Y Inagaki, K Anaka, M Nakao, H Arashi, J Yamaguchi, and N Hagiwara
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Cardiology and Cardiovascular Medicine - Abstract
Background The optimal coronary revascularization strategy for the patients on hemodialysis is yet to be determined. In the real-world practice, we sometimes encounter the rapid deterioration after percutaneous coronary intervention (PCI) to angiographically intermediate but functionally significant stenosis. According to the fractional flow reserve (FFR) based revascularization strategy, the clinical outcome of the deferred lesions is reported to be almost equivalent to that of the lesions received PCI. However, whether the relationship also applies to hemodialysis patients is unclear. Purpose To assess the clinical outcome of the lesions for which revascularization strategy was determined by FFR in patients with hemodialysis. Methods Consecutive 147 vessels in 120 patients with hemodialysis whose revascularization strategy was decided according to the FFR were enrolled in this study. We compared the clinical outcomes of the deferred group (FFR ≥0.80, 87 vessels, 78 patients) with the PCI group (FFR Results The median follow-up period was 2.3 years (interquartile range, 1.5–4.0 years). The beseline characteristics of the lesions and patients were well balanced between the 2 treatment groups except for the distribution of target vessels and FFR value. The cumulative TVF rate was not significantly different between the deferred group and PCI group (2-year event rate 26.7% vs. 17.7%; Log-rank p=0.23). The risk of MACE was also not significantly different between two groups (2-year event rate 35% vs. 30%; Log-rank p=0.48). Conclusion The clinical outcome of the lesions/patients for which received revascularization based on FFR was equivalent to the deferred lesions/patients even in the patients on hemodialysis (2,129/3,000). Funding Acknowledgement Type of funding sources: None. Table 1Figure 1
- Published
- 2021
10. Development of Novel Activatable Fluorescence Probes for Real-Time Identification of Perihilar/Distal Cholangiocarcinoma
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R. Takahashi, T. Ishizawa, Y. Inagaki, M. Tanaka, M. Kamiya, A. Ichida, Y. Kawaguchi, N. Akamatsu, J. Kaneko, J. Arita, T. Ushiku, Y. Urano, and K. Hasegawa
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Hepatology ,Gastroenterology - Published
- 2022
11. Aggressive lipid lowering therapy with pitavastatin and ezetimibe improve cardiovascular outcomes in patients with ST segment elevation myocardial infarction: insights from the HIJ-PROPER Study
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Hiroshi Ogawa, Hiroyuki Arashi, S Ebihara, Junichi Yamaguchi, Nobuhisa Hagiwara, M Nakao, Keiji Tanaka, H Otsuki, Y Inagaki, E Watanabe, and M Nakazawa
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medicine.medical_specialty ,business.industry ,medicine.disease ,Lipid-lowering therapy ,Ezetimibe ,Internal medicine ,medicine ,Cardiology ,ST segment ,In patient ,Myocardial infarction ,Cardiology and Cardiovascular Medicine ,Pitavastatin ,business ,Cardiovascular outcomes ,medicine.drug - Abstract
Aims The purpose of this study was to evaluate the effect of aggressive lipid-lowering therapy with pitavastatin and ezetimibe in patients with ST-segment elevation myocardial infarction (STEMI) as compared with those with other classification of an acute coronary syndrome (ACS) including non-STEMI (NSTEMI) and unstable angina pectoris (UA). Methods This is a post hoc sub-analysis of the HIJ-PROPER study. In the original study, ACS patients with dyslipidemia were randomized to either pitavastatin + ezetimibe therapy or pitavastatin monotherapy. In the present analysis, we divided HIJ-PROPER participants into the STEMI group (n=880) and NSTEMI + UA group (n=841). Cardiovascular events were analyzed between the two groups. The primary endpoint was a composite of major advanced cardiovascular events (MACE; all-cause death, non-fatal myocardial infarction, non-fatal stroke, unstable angina pectoris, and ischemia-driven revascularization) Result During median follow-up period of 3.4 years, the cumulative incidence of the primary endpoint in STEMI group was 31.9% in the pitavastatin+ezetimibe therapy, compared with 39.7% in the pitavastatin-monotherapy (HR, 0.77; 95% CI, 0.62–0.97; p=0.02). However, there was no effect of pitavastatin+ezetimibe therapy on the primary endpoint in the NSTEMI + UA group. Concerning the individual components of the primary endpoint in STEMI group, the percentage of occurrence of all-cause death was significantly lower in the pitavastatin+ezetimibe therapy compared to pitavastatin mono-therapy (14 patients (3.2%) vs. 31 patients (6.9%), respectively; HR, 0.45; 95% CI, 0.23–1.84, p=0.01). Multivariate analysis revealed that use of ezetimibe and prevalence of diabetes mellitus at baseline were independent predictors of primary endpoints in STEMI group (HR, 0.79; 95% CI, 0.63–0.99; p=0.04 for use of ezetimibe, HR 1.54; 95% CI, 1.22–1.94, p=0.0003 for diabetes mellitus). Conclusion Patients with pitavastatin+ezetimibe therapy as compared with pitavastatin-monotherapy had lower cardiovascular event in patients with ST-segment elevation myocardial infarction. Kaplan-Meier curves for primary endpoint Funding Acknowledgement Type of funding source: None
- Published
- 2020
12. Lower levels of high-density lipoprotein cholesterol are associated with increased cardiovascular events in patients with acute coronary syndrome receiving contemporary lipid-lowering therapy
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Nobuhisa Hagiwara, Hiroshi Ogawa, Junichi Yamaguchi, Hiroyuki Arashi, M Nakazawa, H Otsuki, and Y Inagaki
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Cardiovascular event ,medicine.medical_specialty ,Acute coronary syndrome ,Cholesterol ,business.industry ,medicine.disease ,Lipid-lowering therapy ,chemistry.chemical_compound ,High-density lipoprotein ,chemistry ,Ezetimibe ,Internal medicine ,medicine ,Cardiology ,In patient ,Cardiology and Cardiovascular Medicine ,Pitavastatin ,business ,medicine.drug - Abstract
Background This study aimed to elucidate whether high-density lipoprotein cholesterol (HDL-C) at 3-month follow-up for patients receiving contemporary lipid-lowering therapy after acute coronary syndrome (ACS) could predict cardiac events. Methods The HIJ-PROPER study was a multicenter, prospective, randomized trial comparing intensive lipid-lowering therapy (pitavastatin + ezetimibe) and conventional lipid-lowering therapy (pitavastatin monotherapy) after ACS. For the present analysis, the entire cohort was divided into three groups according to HDL-C levels at 3-month follow-up (Group 1, HDL-C ≤43 mg/dL; Group 2, 43–53.6 mg/dL; Group 3; HDL-C ≥53.6 mg/dL). Baseline characteristics and the incidence of the primary endpoint (a composite of all-cause death, non-fatal myocardial infarction, non-fatal stroke, unstable angina pectoris, or ischemia-driven revascularization) were compared among the three groups. Results The primary endpoint was reported in 34.8%, 30.1%, and 24.6% of patients in Groups 1, 2, and 3, respectively. The incidence of the primary endpoint was significantly higher in Group 1 than in Group 3 (hazard ratio [HR], 1.5; 95% confidence interval [CI], 1.19–1.9; p=0.001). Irrespective of the treatment regimen, Group 1 had a significantly higher rate of the primary endpoint than Group 3 (pitavastatin + ezetimibe therapy: HR, 1.6; 95% CI, 1.12–2.22; p=0.01 and pitavastatin monotherapy: HR, 1.4; 95% CI, 1.05–1.98; p=0.02). These trends remained even after adjustment for baseline characteristics and lipid profiles. Conclusions Lower levels of HDL-C at 3-month follow-up are associated with higher incidence of the cardiovascular events in patients with acute coronary syndrome receiving contemporary lipid-lowering therapy. HDL-C levels and Cardiovascular events Funding Acknowledgement Type of funding source: None
- Published
- 2020
13. Tadalafil and the efficacy on the post micturition dribble: Preliminary study
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Kentaro Takezawa, Shinichiro Fukuhara, Hiroshi Kiuchi, Y. Sekii, Norio Nonomura, K. Okada, and Y. Inagaki
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medicine.medical_specialty ,business.industry ,Urology ,media_common.quotation_subject ,lcsh:Diseases of the genitourinary system. Urology ,lcsh:RC870-923 ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Urination ,lcsh:RC254-282 ,Tadalafil ,Medicine ,business ,medicine.drug ,media_common - Published
- 2020
14. Fermionic order by disorder in a van der Waals antiferromagnet
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R., Okuma, D., Ueta, S., Kuniyoshi, Y., Fujisawa, B., Smith, C. H., Hsu, Y., Inagaki, W., Si, T., Kawae, H., Lin, F. C., Chuang, T., Masuda, R., Kobayashi, Y., Okada, R., Okuma, D., Ueta, S., Kuniyoshi, Y., Fujisawa, B., Smith, C. H., Hsu, Y., Inagaki, W., Si, T., Kawae, H., Lin, F. C., Chuang, T., Masuda, R., Kobayashi, and Y., Okada
- Abstract
CeTe₃ is a unique platform to investigate the itinerant magnetism in a van der Waals (vdW) coupled metal. Despite chemical pressure being a promising route to boost quantum fluctuation in this system, a systematic study on the chemical pressure effect on Ce³⁺(4f¹) states is absent. Here, we report on the successful growth of a series of Se doped single crystals of CeTe₃. We found a fluctuation driven exotic magnetic rotation from the usual easy-axis ordering to an unusual hard-axis ordering. Unlike in localized magnetic systems, near-critical magnetism can increase itinerancy hand-in-hand with enhancing fluctuation of magnetism. Thus, seemingly unstable hard-axis ordering emerges through kinetic energy gain, with the self-consistent observation of enhanced magnetic fluctuation (disorder). As far as we recognize, this order-by-disorder process in fermionic system is observed for the first time within vdW materials. Our finding opens a unique experimental platform for direct visualization of the rich quasiparticle Fermi surface deformation associated with the Fermionic order-by-disorder process. Also, the search for emergent exotic phases by further tuning of quantum fluctuation is suggested as a promising future challenge., source:https://www.nature.com/articles/s41598-020-72300-3
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- 2020
15. Application of UAV for Sewer Pipe Inspection
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Y, Inagaki, primary, H, Ikeda, additional, Y, Yato, additional, PK, Takeuchi, additional, and M, Anakura, additional
- Published
- 2020
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16. Diagnostic Role of Measurement of Asbestos Bodies in Bronchoalveolar Lavage Fluid in Patients with Interstitial Lung Diseases
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T. Teramoto, Y. Inagaki, T. Arai, T. Kasai, C. Sugimoto, S. Hayashi, M. Akira, and Y. Inoue
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Pathology ,medicine.medical_specialty ,Bronchoalveolar lavage ,Lung ,medicine.anatomical_structure ,medicine.diagnostic_test ,business.industry ,medicine ,In patient ,business ,medicine.disease_cause ,Asbestos - Published
- 2019
17. Application of phyto-Fenton process in constructed wetland for the continuous removal of antibiotics
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Y. Inagaki, S. Nara, Y. Sakakibara, K. Matsumoto, and V. P. Ranjusha
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Scientific method ,Environmental engineering ,Constructed wetland ,Environmental science - Abstract
Phyto-Fenton process utilizes the endogenous hydrogen peroxide in plants to degrade organic pollutants in presence of iron catalyst. In this study, we have applied the magnetite particles in continuous treatment system of constructed wetland (CW) to study the effectiveness in removing sulfamethoxazole (SMX) antibiotics. Experimental results demonstrated that SMX was removed by constructed wetlands in the presence and absence of magnetite fine particles. OH radical formation was observed in the plant+Fe system with electron spin resonance spectroscopy. The magnetite addition favoured the plant growth and endogenous H2O2. However, enhanced treatments by phyto-Fenton process were not enhanced in the presence of magnetite particles, but the plants+soil CWs showed better removal efficiencies compared to the soil CWs.
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- 2020
18. Polarization Sensitive Femtosecond Mid-Infrared Spectrometer Using Chirped-Pulse Upconversion
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Ryosuke Nakamura, Nobuhiro Umemura, Tomosumi Kamimura, and Y. Inagaki
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Materials science ,Spectrometer ,Physics::Optics ,Polarization (waves) ,01 natural sciences ,Photon upconversion ,010309 optics ,0103 physical sciences ,Femtosecond ,Physics::Atomic and Molecular Clusters ,Molecular symmetry ,Chirp ,Physics::Chemical Physics ,Atomic physics ,Spectroscopy ,Rotational–vibrational coupling - Abstract
Polarization sensitive femtosecond mid-infrared spectrometer is developed based on chirped-pulse upconversion. Polarization and frequency dependence of the pump pulse on the vibrational coupling between the CO stretching modes of a metal carbonyl complex reveals the appearance of Raman-active vibrations due to a slight decrease in the molecular symmetry.
- Published
- 2018
19. Isometric contraction of the quadriceps reduces the knee injection pain via the superolateral approach
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T. Nagano, Tadashi Fujii, Y. Inagaki, M. Wada, and Yoshio Tanaka
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Rheumatology ,business.industry ,Anesthesia ,Knee injection ,Biomedical Engineering ,Medicine ,Orthopedics and Sports Medicine ,Isometric exercise ,business - Published
- 2019
20. Bladder primary afferent pathways to the spinal cord in mice
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Norichika Ueda, Hiroshi Kiuchi, Shinichiro Fukuhara, M. Kondo, Y. Sekii, Norio Nonomura, Y. Inagaki, S. Shimada, and Kentaro Takezawa
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Pathology ,medicine.medical_specialty ,Primary (chemistry) ,medicine.anatomical_structure ,business.industry ,Urology ,Afferent ,Medicine ,business ,Spinal cord - Published
- 2019
21. Pubis-rectum length and early recovery of continence after robot-assisted laparoscopic prostatectomy
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Hiroshi Kiuchi, Y. Inagaki, Shinichiro Fukuhara, Y. Sekii, M. Uemura, Norichika Ueda, Ryoichi Imamura, Kazutoshi Fujita, Kentaro Takezawa, and Norio Nonomura
- Subjects
medicine.medical_specialty ,medicine.anatomical_structure ,business.industry ,Urology ,medicine ,Early recovery ,Robot assisted laparoscopic prostatectomy ,Rectum ,business ,Surgery - Published
- 2019
22. Cluster-Based Haldane State in an Edge-Shared Tetrahedral Spin-Cluster Chain: Fedotovite K_{2}Cu_{3}O(SO_{4})_{3}
- Author
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M, Fujihala, T, Sugimoto, T, Tohyama, S, Mitsuda, R A, Mole, D H, Yu, S, Yano, Y, Inagaki, H, Morodomi, T, Kawae, H, Sagayama, R, Kumai, Y, Murakami, K, Tomiyasu, A, Matsuo, and K, Kindo
- Abstract
Fedotovite K_{2}Cu_{3}O(SO_{4})_{3} is a candidate of new quantum spin systems, in which the edge-shared tetrahedral (EST) spin clusters consisting of Cu^{2+} are connected by weak intercluster couplings forming a one-dimensional array. Comprehensive experimental studies by magnetic susceptibility, magnetization, heat capacity, and inelastic neutron scattering measurements reveal the presence of an effective S=1 Haldane state below T≅4 K. Rigorous theoretical studies provide an insight into the magnetic state of K_{2}Cu_{3}O(SO_{4})_{3}: an EST cluster makes a triplet in the ground state and a one-dimensional chain of the EST induces a cluster-based Haldane state. We predict that the cluster-based Haldane state emerges whenever the number of tetrahedra in the EST is even.
- Published
- 2017
23. Analysis of the influence of collagen fibres in the dermis on skin optical reflectance by Monte Carlo simulation in a nine-layered skin model
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Yuki Ogura, Takeshi Yasui, Y Masuda, Y Inagaki, and Y Aizu
- Subjects
Adult ,Models, Anatomic ,medicine.medical_specialty ,Materials science ,Monte Carlo method ,Skin Pigmentation ,Dermatology ,Absorption (skin) ,01 natural sciences ,Light scattering ,010309 optics ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Dermis ,Collagen fibres ,0103 physical sciences ,medicine ,Humans ,Optical reflectance ,Aged ,integumentary system ,Spectrum Analysis ,Colorimeter ,Optical Imaging ,Middle Aged ,medicine.anatomical_structure ,Cheek ,Reflection (physics) ,Female ,Collagen ,Monte Carlo Method ,Biomedical engineering - Abstract
Background Collagen fibres in the dermis play an important structural role in the skin. Age-related changes to these fibres cause wrinkles and slackness of facial skin. However, it is not clear how dermal collagen fibres affect skin colour. The purpose of this study was to clarify the influence of altered collagen fibres on skin colour, using both experimental measurement of fibre density and Monte Carlo simulations in an optical model of skin. Methods Reflection spectra were measured from the cheeks of 12 Japanese women (22-65 years old) by spectral colorimeter. Two-dimensional autocorrelation functions were calculated from second harmonics generation (SHG) images acquired from the same locations and used to calculate collagen density indices. Monte Carlo simulations of light reflectance by skin were performed using a nine-layered model that precisely imitates skin structure. The relationship between dermal collagen fibre density and skin reflection spectra was analysed. Results A positive correlation was found between collagen density and skin brightness, as measured by the colour value, L* (using the L*a*b* colour space). In addition, collagen density showed a strong inverse correlation with age and with the optical absorption of dermis. The Monte Carlo simulations showed that the reflection spectrum of skin changes when the scattering coefficient of the dermis is altered. These changes were the same for simulated and experimentally measured reflection spectra. Conclusion When collagen fibre density in the upper dermis is decreased with age, skin colour becomes less bright because light scattering in the skin is decreased.
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- 2017
24. Identification of novel susceptibility loci for tuberous sclerosis complex (TSC) in the Japanese population
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Yu Ishizuya, Satoru Miyano, M. Uemura, Ryoichi Imamura, K. Katayama, K. Matsuda, R. Yamaguchi, Shinichiro Fukuhara, M. Kaneda, Y. Inagaki, Y. Yamamoto, Norio Nonomura, and K. Fiujita
- Subjects
Genetics ,Tuberous sclerosis ,business.industry ,Urology ,Susceptibility locus ,Medicine ,Identification (biology) ,Japanese population ,business ,medicine.disease - Published
- 2019
25. Wear analysis of hydrogen-free diamond-like carbon coatings under a lubricated condition
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Tsuyoshi Higuchi, Hiroyuki Kousaka, Noritsugu Umehara, Yutaka Mabuchi, and Y. Inagaki
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Materials science ,Diamond-like carbon ,Metallurgy ,Ion plating ,Surfaces and Interfaces ,Vacuum arc ,Sputter deposition ,engineering.material ,Condensed Matter Physics ,Hardness ,Surfaces, Coatings and Films ,Coating ,Mechanics of Materials ,Materials Chemistry ,engineering ,Graphite ,Layer (electronics) - Abstract
Hydrogen-free diamond-like carbon (DLC) coatings were formed using four different deposition methods: trigger-type arc ion plating, laser-discharge-induced arc ion plating, filtered cathodic vacuum arc ion plating and magnetron sputtering. Wear tests were conducted on the coatings under a lubricated condition to investigate the effect of their surface hardness on wear, as well as the phase transformation from sp 3 to sp 2 and the influence of their surface properties. The results showed that DLC coating wear tended to decrease with higher hardness and that surface droplets (particles) formed during the deposition process tended to have the effect of increasing wear. Further wear testing was done using thicker coating samples to investigate the effect of the droplets in more detail. The results showed that abrasive wear tended to occur accompanying the falling out of droplets from inside the coating. An examination of such droplets by electron energy-loss spectroscopy using a transmission electron microscope (TEM-EELS) revealed that they originated from sputtered graphite debris that was not completely melted during the coating deposition process and served as the nucleus for droplet growth. Additionally, the structure of the droplet-coating interface was found to be a weak sp 2 -rich layer.
- Published
- 2013
26. Periostin expression in inflammatory and non-inflammatory osteoarthritis and rheumatoid arthritis
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David J. Mahoney, Nicholas A. Athanasou, Akira Kudo, Y. Inagaki, T. Kashima, and A. Mantoku
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030203 arthritis & rheumatology ,business.industry ,Biomedical Engineering ,030229 sport sciences ,Osteoarthritis ,Periostin ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Rheumatoid arthritis ,Immunology ,medicine ,Orthopedics and Sports Medicine ,business - Published
- 2016
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27. Light‐induced effects on the radiative recombination rate of electron‐hole pairs in a‐Si:H
- Author
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C. Ogihara, Y. Inagaki, and Kazuo Morigaki
- Subjects
Amorphous silicon ,chemistry.chemical_compound ,Photoluminescence ,Chemistry ,Carrier generation and recombination ,Significant difference ,Radiative transfer ,Light induced ,Spontaneous emission ,Atomic physics ,Condensed Matter Physics ,Recombination - Abstract
Temperature variation of radiative recombination rate obtained for defect photoluminescence (PL) in high-quality a-Si:H after illumination of intense pulsed light is presented and compared with results previously reported for defective a-Si:H films. We have not found significant difference between the temperature variation of the rate of radiative recombination at photo-created radiative defects and that at native radiative defects. This fact suggests the recombination processes at the photo-created defects and the native defects are similar. The temperature dependence of the radiative recombination rates in a-Si:H is predicted by a model of the recombination processes for various cases of different density of deep and strongly localised tail states. Our recent experimental results for the principal PL and defect PL coincide with the prediction of the model. (© 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
- Published
- 2011
28. 1H-NMR studies of quantum spin chain system (CH3)2NH2CuCl3at very low temperature
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Y Inagaki, Y. Nishisaka, T Asano, K. Kumagai, and Yoshinori Furukawa
- Subjects
History ,Field (physics) ,Chemistry ,Chain system ,Proton NMR ,Physical chemistry ,Dilution refrigerator ,Quantum spin liquid ,Magnetic phase diagram ,Computer Science Applications ,Education - Abstract
We report 1H NMR results for (CH3)2NH2CuCl3measured at very low temperature down to 0.1 K using a dilution refrigerator. Field induced magnetic ordered state is revealed by the NMR measurements and a magnetic phase diagram for the system is proposed.
- Published
- 2006
29. W. Sasaki: Aquinas on the Human Being: The Transcendence of the Human Being as Person
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Y. Inagaki
- Subjects
Psychoanalysis ,Transcendence (philosophy) ,Philosophy ,Social psychology ,Human being - Published
- 2006
30. Oxide-Layer Thickness Effect for Surface Roughness Using Low-Pressure Arc
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Toru Iwao, Atsushi Sato, M. Yumoto, and Y. Inagaki
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Nuclear and High Energy Physics ,Auger electron spectroscopy ,Materials science ,business.industry ,Oxide ,Equivalent oxide thickness ,Surface finish ,Vacuum arc ,Condensed Matter Physics ,Cathode ,law.invention ,chemistry.chemical_compound ,Optics ,chemistry ,law ,Surface roughness ,Composite material ,business ,Layer (electronics) - Abstract
Low-pressure arc cleaning is a process for removing an oxide layer. Currently, chemical and mechanical means are typically used to remove such layers. However, both methods present difficulties such as a liquid waste, dust, and noise. Regarding the low-pressure arc cleaning, waste comes from one source: the oxide layer. In addition, the cathode spot has very high temperatures that are sufficient to remove the oxide layer. This paper describes the removal of the nanometer-thick oxide layer from a thin metal plate. An oxide layer of 27-157 nm was removed, thereby, obtaining a smooth surface whose respective arithmetical mean height (Ra) and average length of an outline curve element (R sm) are 0.04 and 6.4 mum. In that case, Ra and R sm increased with an increasing oxide-layer thickness at 397-1680 nm. Those results depend on the oxide-layer thickness. Therefore, although the surface is cratered and rough after a cathode-spot treatment on the chemical oxide layer (6.7 nm), a smooth surface is obtainable after the cathode-spot treatment on the thermal oxide layer (27, 66, and 157 nm). Surface roughness depends on the processing time to produce one crater, which depends on the oxide-layer thickness
- Published
- 2006
31. Inhibitory effects of macrocarpals on the biological activity of Porphyromonas gingivalis and other periodontopathic bacteria
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Satoshi Shizukuishi, Yumiko Yamamoto, Y. Inagaki, K. Kataoka, Kazuhiko Maeda, Kenji Osawa, and Hideki Nagata
- Subjects
Microbiology (medical) ,Immunology ,Microbiology ,Bacterial Adhesion ,Prevotella nigrescens ,Bacterial Proteins ,Endopeptidases ,Protease Inhibitors ,General Dentistry ,Bacteroidaceae ,Porphyromonas gingivalis ,Eucalyptus ,Virulence ,biology ,Plant Extracts ,Prevotella intermedia ,Treponema denticola ,biology.organism_classification ,Anti-Bacterial Agents ,Plant Leaves ,Cysteine Endopeptidases ,stomatognathic diseases ,Actinobacillus ,Fusobacterium nucleatum ,Sesquiterpenes ,Bacteria - Abstract
Background/aims: Macrocarpals, which are phloroglucinol derivatives contained in eucalyptus leaves, exhibit antimicrobial activity against a variety of bacteria including oral bacteria. This study examined effects of macrocarpals A, B, and C on periodontopathic bacteria, especially Porphyromonas gingivalis. Methods: Macrocarpals A, B, and C were purified from a 60% ethanol-extract of Eucalyptus globules leaves. To investigate antibacterial activity, representative periodontopathic bacteria were cultured in media with or without various amounts of macrocarpals; subsequently, the optical density at 660 nm was measured. Macrocarpal inhibition of P. gingivalis Arg- and Lys-specific proteinases was assessed by spectrofluorophotometric assay and sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis. The effect of macrocarpals on P. gingivalis binding to saliva-coated hydroxyapatite beads was examined with 3H-labeled P. gingivalis. Results: Growth of P. gingivalis was inhibited more strongly than growth of Prevotella intermedia or Prevotella nigrescens and Treponema denticola by macrocarpals, however, Actinobacillus actinomycetemcomitans and Fusobacterium nucleatum were much more resistant. Macrocarpals inhibited P. gingivalis Arg- and Lys-specific proteinases in a dose-dependent manner. The enzyme-inhibitory effect of macrocarpals was confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis in which hemoglobin degradation by P. gingivalis proteinase was inhibited by macrocarpals. P. gingivalis binding to saliva-coated hydroxyapatite beads was also strongly attenuated by macrocarpals. Conclusions: Macrocarpals A, B and C demonstrated antibacterial activity against periodontopathic bacteria. Among tested bacteria, P. gingivalis displayed the greatest sensitivity to macrocarpals; additionally, its trypsin-like proteinase activity and binding to saliva-coated hydroxyapatite beads were inhibited by macrocarpals. These results indicate that eucalyptus leaf extracts may be useful as a potent preventative of periodontal disease.
- Published
- 2006
32. Clonidine premedication effects on inhaled induction with sevoflurane in adults: a prospective, double-blind, randomized study
- Author
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Y Inagaki, T Watanabe, and Y Ishibe
- Subjects
Adult ,Methyl Ethers ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Blood Pressure ,Placebo ,Clonidine ,Sevoflurane ,Double-Blind Method ,Heart Rate ,Heart rate ,Intubation, Intratracheal ,medicine ,Humans ,Intubation ,Prospective Studies ,Analgesics ,Dose-Response Relationship, Drug ,Inhalation ,business.industry ,Tracheal intubation ,Drug Synergism ,General Medicine ,Middle Aged ,Surgery ,Anesthesiology and Pain Medicine ,Patient Satisfaction ,Anesthesia ,Anesthetics, Inhalation ,Female ,Premedication ,Anesthesia, Inhalation ,business ,Preanesthetic Medication ,medicine.drug - Abstract
Background: The purpose of this study was to evaluate whether oral clonidine premedication becomes an alternative to N2O in terms of shortening the induction time and attenuation of the adrenergic response to tracheal intubation during inhalation induction with sevoflurane, and to evaluate the quality of anesthetic induction according to the patient's satisfaction. Methods: We studied 84 female patients who were randomly allocated into four study groups: Groups I and II received a placebo orally, and Groups III and IV received clonidine at 150 and 300 µg, respectively, 90 min before induction of anaesthesia. Patients were anesthetized using a triple-deep-breath technique with 5% sevoflurane in Groups I, III and IV, and with 60% N2O−5% sevoflurane in group II. Results: Induction time was significantly longer (P
- Published
- 2006
33. Thermal shock of porous silicon nitride with preferentially aligned grains
- Author
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Luc J. Vandeperre, Y. Inagaki, and William Clegg
- Subjects
Thermal shock ,Materials science ,Mechanical Engineering ,Nitride ,Condensed Matter Physics ,Porous silicon ,Cracking ,chemistry.chemical_compound ,Silicon nitride ,chemistry ,Volume (thermodynamics) ,Mechanics of Materials ,Volume fraction ,General Materials Science ,Composite material ,Porosity - Abstract
We studied the thermal shock resistance of a silicon nitride containing elongated and preferentially aligned grains with different volume fractions of pores, ranging from 0 to 0.27. It was found that an increase in the volume fraction of pores decreased both the strength and the temperature through which the sample must be quenched to cause cracking. However, at intermediate values of the porosity (0.07), the temperature change required to cause cracking was much smaller than predicted. Observations of the resulting damage suggested that this had occurred because of the formation of cracks just underneath and parallel to the cooled surface of the sample that were able to change the direction of their growth. The extent of cracking was found to be only very weakly dependent on the volume fraction of pores, consistent with calculations of the variation of crack driving force within the sample.
- Published
- 2003
34. Second-harmonic generation of a novel transparent material: N,N-diphenyl-8-[2-(4-pyridinyl)ethenyl]-dibenzofuran-2-ylamine
- Author
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Y Inagaki, Jun Kawamata, and M Akiba
- Subjects
Evanescent wave ,Stereochemistry ,Organic Chemistry ,Second-harmonic generation ,Nonlinear optics ,Atomic and Molecular Physics, and Optics ,Cutoff frequency ,Electronic, Optical and Magnetic Materials ,Inorganic Chemistry ,Dibenzofuran ,chemistry.chemical_compound ,Reflection (mathematics) ,chemistry ,Optical materials ,Physical chemistry ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,Spectroscopy - Abstract
N,N-diphenyl-8-[2-(4-pyridinyl)ethenyl]-dibenzofuran-2-ylamine has been synthesized as a novel second-harmonic generation (SHG) material. From reflection measurement in powder form, the SHG of the titled compound is found to be nine times as intense as that of urea. An effective d coefficient by means of second-harmonic wave generated with the evanescent wave (SHEW) method is estimated to be 3 pm/V. The cutoff wavelength of the compound is 370 nm.
- Published
- 2003
35. 欠陥光ルミネセンスの熱焼鈍及びa-Si:Hにおける電子正孔対の再結合速度
- Author
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Y. Inagaki, A. Taketa, and K. Morigakib
- Subjects
Silicon ,Luminescence ,Amorphous ,Non-radiative recombination ,Defects - Published
- 2012
36. Thermal quenching of defect photoluminescence and recombination rates of electron–hole pairs in a-Si:H
- Author
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A. Taketa, C. Ogihara, Y. Inagaki, and Kazuo Morigaki
- Subjects
Photoluminescence ,Materials science ,Carrier generation and recombination ,Condensed Matter Physics ,Electronic, Optical and Magnetic Materials ,Amorphous solid ,Materials Chemistry ,Ceramics and Composites ,Spontaneous emission ,Atomic physics ,Spectroscopy ,Luminescence ,Recombination ,Non-radiative recombination - Abstract
Temperature variation of non-radiative recombination rate, competing with defect photoluminescence (PL), has been obtained from characteristic lifetimes estimated from experiments by means of frequency resolved spectroscopy (FRS) for a-Si:H films after illumination of pulsed light. Conventional interpretation of thermal quenching of the PL in a-Si:H, where the non-radiative recombination rate has an activation-type temperature dependence and the radiative recombination rate is independent of the temperature, is not suitable to explain the experimental results of the defect PL. The temperature variation of the non-radiative recombination rate obtained for the defect PL is well described by a theory of Englman and Jortner for the case of strong electron–phonon coupling.
- Published
- 2012
37. Ultrafast nonlinear response of high density carriers at silicon surface detected by simultaneous measurements of transient reflecting first and second order diffractions
- Author
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Kenji Katayama, Y. Inagaki, and Tsuguo Sawada
- Subjects
Diffraction ,Silicon ,Chemistry ,business.industry ,Scattering ,General Physics and Astronomy ,chemistry.chemical_element ,Molecular physics ,Optics ,Heat generation ,Charge carrier ,business ,Refractive index ,Ultrashort pulse ,Surface states - Abstract
The simultaneous detections of transient reflectivity (TR), transient reflecting first and second order diffraction signals, at a silicon surface revealed that each signal reflected different physical processes of carrier dynamics under a high pump power of 5 mJ/cm2. It was shown that the second order diffraction could detect a refractive index change which was not linearly dependent on the excited carrier density, and it was suggested that the nonlinearity was caused by many-body interactions among carriers at the band-edge states. The dynamics observed with the second order diffraction corresponded to the recombination of the band-edge carriers. Analysis of the first and second order diffractions in combination with the recently developed spectroscopic detection provided selective information on the ultrafast carrier and heat dynamics for a silicon surface, that is, carrier-phonon scattering, recombination of carriers, heat generation, and diffusion. Additionally, it was shown the TR might allow observa...
- Published
- 2002
38. An (La,Sr)(Co,Cu)O3−δ cathode for reduced temperature SOFCs
- Author
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K. Yasumoto, Masayuki Dokiya, M Shiono, and Y Inagaki
- Subjects
Chemistry ,Inorganic chemistry ,Analytical chemistry ,chemistry.chemical_element ,General Chemistry ,Conductivity ,Condensed Matter Physics ,Copper ,Oxygen ,Cathode ,law.invention ,chemistry.chemical_compound ,Lanthanum oxide ,law ,Electrical resistivity and conductivity ,Ionic conductivity ,General Materials Science ,Strontium oxide - Abstract
The oxygen nonstoichiometry of (La,Sr)(Co,Cu)O 3− δ (LSCC) was measured thermogravimetrically. It was found that LSCC has no oxygen excess region. Its behavior is similar to (La,Sr)FeO 3− δ (LSF) but not to (La,Sr)MnO 3± δ (LSM). The electrical conductivity decreases as compared to (La,Sr)CoO 3− δ (LSC). However, it was expected that the ionic conductivity in LSCC would increase, as is suggested from electrical conductivity measurement and oxygen nonstoichiometry measurements. High temperature XRD analysis showed the elimination of phase transformations by addition of Cu yet with no reduction in the thermal expansion coefficient. The cathode activity of LSCC, the electrode interfacial conductivity, σ E , was 15.32 S cm −2 in air at 1073 K. The electrode activity of LSCC is better than that of LSC, although the electrical conductivity of LSCC is lower.
- Published
- 2002
39. On synchronized evolution of the network of automata
- Author
-
Y. Inagaki
- Subjects
TheoryofComputation_COMPUTATIONBYABSTRACTDEVICES ,Nested word ,Computer science ,Timed automaton ,ω-automaton ,Nonlinear Sciences::Cellular Automata and Lattice Gases ,Theoretical Computer Science ,Mobile automaton ,Computational Theory and Mathematics ,DFA minimization ,Continuous spatial automaton ,Automata theory ,Quantum finite automata ,Algorithm ,Computer Science::Formal Languages and Automata Theory ,Software - Abstract
One of the tasks in machine learning is to build a device that predicts each next input symbol of a sequence as it takes one input symbol from the sequence. We studied new approaches to this task. We suggest that deterministic finite automata (DFA) are good building blocks for this device, together with genetic algorithms (GAs), which let these automata "evolve" to predict each next input symbol of the sequence. Moreover, we study how to combine these highly fit automata so that a network of them would compensate for each others' weaknesses and predict better than any single automaton. We studied the simplest approaches to combine automata: building trees of automata with special-purpose automata, which may be called switchboards. These switchboard automata are located on the internal nodes of the tree, take an input symbol from the input sequence just as other automata do, and predict which subtree will make a correct prediction on each next input symbol. GAs again play a crucial role in searching for switchboard automata. We studied various ways of growing trees of automata and tested them on sample input sequences, mainly note pitches, note durations and up/down notes of Bach's Fugue IX. The test results show that DFAs together with GAs seem to be very effective for this type of pattern learning task.
- Published
- 2002
40. Ultrafast dynamics at a silicon surface detected with femtosecond transient reflecting grating spectroscopy
- Author
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Y. Inagaki, Kenji Katayama, Tsuguo Sawada, and K. Sugai
- Subjects
Materials science ,Auger effect ,Silicon ,business.industry ,General Physics and Astronomy ,chemistry.chemical_element ,Carrier lifetime ,Grating ,Molecular physics ,symbols.namesake ,Optics ,chemistry ,Picosecond ,Rise time ,Heat generation ,Femtosecond ,symbols ,business - Abstract
The recently developed spectroscopic transient reflecting grating technique with a time resolution of 200 fs was applied to a silicon surface under the pump intensity of more than 1 mJ/cm2. This method provides information on excited free carrier dynamics and subsequent heat generation and diffusion selectively based on appropriate choice of probe wavelength. With regard to the thermal component, the temperature at the surface increased within several picoseconds and then decayed after about 300 ps. As the pump intensity was increased, the maximum temperature rise showed a nonlinear dependence on it, and also the temperature rise time became faster. The results led to the conclusion that the carrier dynamics causing a temperature rise at a silicon surface is dominated mainly by Auger recombination, not by the decay to a band edge under the high carrier density conditions.
- Published
- 2002
41. DC prestressing effect on breakdown characteristic of insulating paper in liquid nitrogen and insulating oil
- Author
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Takato Masuda, Y. Inagaki, Masayuki Nagao, Tomohiro Kawashima, Y. Ashibe, and Yoshinobu Murakami
- Subjects
Materials science ,business.industry ,Transformer oil ,Electrical engineering ,Electrical insulation paper ,Liquid nitrogen ,Composite material ,business - Published
- 2014
42. The improvement of the characteristics of ramp-edge junctions with interface modified barriers
- Author
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Y. Inagaki, Akira Fujimaki, Hisao Hayakawa, Masahiro Horibe, and T. Ito
- Subjects
Josephson effect ,High-temperature superconductivity ,Materials science ,Condensed matter physics ,Annealing (metallurgy) ,Metals and Alloys ,Magnetic field effect ,Condensed Matter Physics ,law.invention ,Amorphous solid ,Magnetic field ,law ,Electrode ,Materials Chemistry ,Ceramics and Composites ,Critical current ,Electrical and Electronic Engineering - Abstract
We have studied the effect of process parameters on uniformity and reproducibility in the engineered barrier ramp-edge Josephson junctions with YBa2Cu3Ox electrodes. The engineered barrier is formed during an etching and annealing process. We investigate excess currents in the junctions by analysing the magnetic field modulations of critical current. The observed excess currents in this study decrease exponentially with increasing annealing temperature. We thus speculate that these excess currents flow via superconductive pinholes in the barrier of the interface-engineered junction (IEJ) due to the formation of CuO2 plane which is formed during the barrier formation. We try to patch these pinholes by substituting Cu and Y for Ga and Pr, respectively. We have found that deposition of amorphous PrGaO3 (PGO) in the IEJ barrier dramatically decreases the excess current.
- Published
- 2001
43. Reproducibility and controllability of critical current for ramp-edge interface-modified junctions
- Author
-
Y. Yoshinaga, K. Ohnishi, Masahiro Horibe, M. Maruyama, T. Ito, Akira Fujimaki, Hisao Hayakawa, Y. Inagaki, and Gen-ichiro Matsuda
- Subjects
Josephson effect ,Reproducibility ,Materials science ,Annealing (metallurgy) ,Doping ,Analytical chemistry ,Energy Engineering and Power Technology ,Condensed Matter Physics ,Acceleration voltage ,Electronic, Optical and Magnetic Materials ,Ion ,Controllability ,Tunnel effect ,Electrical and Electronic Engineering - Abstract
We have investigated the relationship between process parameters and junction characteristics ( I c , R n ) of interface-modified junctions (IMJs) made on MgO substrates, and have derived empirical equations from the obtained relationships. Thin and uniform tunnel barriers of IMJs were formed by ion irradiation and annealing. We chose accelerating voltage ( V acc ), etching time ( t etch ) and deposition temperature ( T dep ) as the process parameters for the control of critical current ( I c ). We prepared four different samples fabricated in the same conditions, and examined the reproducibility and controllability of I c . The obtained I c s were very close to the expected value, and the run-to-run 1 σ -spread was 20% at 4.2 K. Furthermore, we could also control I c of IMJ made on SrTiO 3 substrates.
- Published
- 2001
44. Preparation of ramp-edge interface modified junctions for HTS SFQ circuits
- Author
-
Masahiro Horibe, Hisao Hayakawa, Gen-ichiro Matsuda, Y. Inagaki, Akira Fujimaki, and T. Ito
- Subjects
Empirical equations ,Josephson effect ,Reproducibility ,Materials science ,High-temperature superconductivity ,Annealing (metallurgy) ,Analytical chemistry ,Condensed Matter Physics ,Acceleration voltage ,Electronic, Optical and Magnetic Materials ,law.invention ,Controllability ,law ,Electrical and Electronic Engineering ,Electronic circuit - Abstract
We have studied the properties of ramp-edge interface modified Josephson junctions (IMJs) whose barriers are formed during the etching process and subsequent annealing process. We investigate the effect of process parameters on junction characteristics (I/sub c/, R/sub n/) and obtain an empirical equation concerning their relationship. We select accelerating voltage (V/sub acc/) and etching time (t/sub etch/) for the control of I/sub c/ of IMJs and set the target value of I/sub c/ at 4.2 K to 500 /spl mu/A in this study. This target value can be realized by V/sub acc/=500 V and t/sub etch/=20 min from our empirical equation. We prepare four different samples fabricated in the same conditions, and examine the reproducibility and controllability of I/sub c/. The obtained I/sub c/s are very close to the target value, and the run-to-run spread is confined to about 150 /spl mu/A. The reproducibility and controllability of I/sub c/ are improved compared to our previous data of junctions with artificial barriers.
- Published
- 2001
45. Ultrafast two-step thermalization processes of photoexcited electrons at a gold surface: Application of a wavelength-selective transient reflecting grating method
- Author
-
Tsuguo Sawada, Y. Inagaki, and Kenji Katayama
- Subjects
Physics ,Wavelength ,Thermalisation ,Optics ,business.industry ,Electron ,Gold surface ,Transient (oscillation) ,Grating ,Atomic physics ,Spectroscopy ,business ,Ultrashort pulse - Published
- 2000
46. Sensorless initial rotor position estimation of surface permanent-magnet synchronous motor
- Author
-
S. Nakashima, I. Miki, and Y. Inagaki
- Subjects
Physics ,Rotor (electric) ,Squirrel-cage rotor ,Stator ,Permanent magnet synchronous generator ,AC motor ,Industrial and Manufacturing Engineering ,Wound rotor motor ,law.invention ,Quantitative Biology::Subcellular Processes ,Control and Systems Engineering ,law ,Control theory ,Electrical and Electronic Engineering ,Synchronous motor ,Induction motor - Abstract
This paper presents a method of estimating the initial rotor position of a surface permanent-magnet synchronous motor without a position sensor. The estimation is performed by using the nonlinear magnetization characteristics of the stator core caused by the magnet of the rotor. This method is based on the principle that the d-axis current value for the voltage vector applied to the motor under some conditions increases as the voltage vector generated from the inverter approaches the N pole of the rotor. During the estimation process, the rotor is practically at standstill. The experimental results show that the average of the estimation error is /spl plusmn/3.8 electrical degrees.
- Published
- 2000
47. Spatiotemporal expression of matrix metalloproteinase-1 in progression of nonalcoholic steatohepatitis
- Author
-
H, Yokomori, primary, Y, Inagaki, additional, W, Ando, additional, M, Hara, additional, T, Komiyama, additional, S, Kojima, additional, M, Oda, additional, H, Kuroda, additional, Y, Suzuki, additional, and I, Okazaki, additional
- Published
- 2016
- Full Text
- View/download PDF
48. Time-resolved carrier drag effect in quantum wells and wires
- Author
-
Y Inagaki, Hiroyuki Sakaki, Yasushi Nagamune, A Takahashi, M Seyama, K Kinoshita, Takeshi Noda, and M Watanabe
- Subjects
Physics ,Condensed matter physics ,Condensed Matter::Other ,Scattering ,Exciton ,Quantum wire ,Relaxation (NMR) ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Condensed Matter Physics ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Condensed Matter::Materials Science ,Drag ,Shutter ,Ultrashort pulse ,Quantum well - Abstract
We demonstrate time-resolved measurements of carrier drag effect in modulation-doped n-type GaAs/AlGaAs quantum wells and edge wires by using a micro-photoluminescence measurement setup and a novel ultrafast and high repetition shutter camera. As well as we demonstrate time-resolved two-dimensional images of carrier drag effect, we found that the relaxation time of exciton–electron scattering and exciton–lattice scattering are very long in comparison with previous studies and theories. In addition, the relaxation times in the edge-wires is longer than those in the wells, probably resulting in high exciton mobility in the edge wires.
- Published
- 1998
49. A consideration to reduce the potential hazard of I-129 in radioactive wastes
- Author
-
H. Nakamura, Y. Inagaki, M. Senoo, and S. Tashiro
- Subjects
Nuclear transmutation ,Equivalent dose ,Radiochemistry ,Energy Engineering and Power Technology ,chemistry.chemical_element ,Radioactive waste ,Isotope dilution ,Iodine ,Conditioning process ,Spent nuclear fuel ,Nuclear Energy and Engineering ,chemistry ,Environmental science ,Safety, Risk, Reliability and Quality ,Waste Management and Disposal ,Dissolution - Abstract
Transmutation of 129 I to 130 I by (n, γ) reaction and isotope dilution with stable iodine were discussed. The transmutation in LWR is calculated by supposing that targets irradiated for 25 years are substituted with new targets. The result showed that initial amount of 129 I will be reduced to 11.5%. In order to lower dose equivalent of general public than 0.1mSv/y, 400 times isotope dilution of 129 I is required. The feasibility of the isotope dilution was discussed at dissolution process of spent fuel, conditioning process of the waste and disposal conditions.
- Published
- 1998
50. Serotyping of Streptococcus pyogenes isolated from common and severe invasive infections in Japan, 1990–5: implication of the T3 serotype strain-expansion in TSLS
- Author
-
S. Yamai, Y. Inagaki, A. Matsushima, Shoko Murayama, D. Tanaka, Aki Tamaru, T. Konda, Chihiro Katsukawa, A. Katayama, M. Tomita, Y. Fuchi, Haruo Watanabe, K. Hoashi, and Y. Gyobu
- Subjects
Serotype ,biology ,Epidemiology ,Toxic shock syndrome ,Seroepidemiologic Studies ,Streptococcaceae ,biology.organism_classification ,medicine.disease ,medicine.disease_cause ,Virology ,Group A ,Microbiology ,Infectious Diseases ,Streptococcus pyogenes ,medicine ,biology.protein ,Typing ,Antibody - Abstract
To clarify the relationship between the epidemics of severe invasive group A streptococcal infections (streptococcal Toxic Shock-Like Syndrome; TSLS) and common group A streptococcal infections in Japan, we examined the T serotypes of S. pyogenes strains (group A streptococci) isolated from clinical specimens of the streptococcal infections (17999 cases) in the period 1990–5, including the severe infections (TSLS) (29 cases) in the period 1992–5. Characteristic points of the analyses were: (1) dominant serotypes of the infections in these periods were T12, T4, T1, T28 and TB3264, which were consistently isolated; (2) isolates of T3 rapidly increased through 1990 to 1994 while T6 decreased in the period 1990–3; (3) when Japanese area was divided into three parts, T3 serotype tended to spread out from the north-eastern to the south-western area; (4) strains of T3 and T1 serotypes were dominant in the TSLS. Dominant-serotype strains of streptococcal infections did not always induce severe infections and dominance of T3 serotype in the TSLS seemed to be correlated with the increase of T3 in streptococcal infections. These results may indicate that certain clones of S. pyogenes are involved in the pathogenesis of the TSLS.
- Published
- 1997
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