1. Prognostic Utility of Soluble TREM‐1 in Predicting Mortality and Cardiovascular Events in Patients With Acute Myocardial Infarction
- Author
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Yun Kai Wang, Jia Ni Tang, Yun Li Shen, Bo Hu, Chun Yu Zhang, Ming Hui Li, Rui Zhen Chen, Jun Bo Ge, and Xue Bo Liu
- Subjects
acute myocardial infarction ,all‐cause mortality ,major adverse cardiac event ,prognosis ,triggering receptor expressed on myeloid cells‐1 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background Triggering receptor expressed on myeloid cells‐1 (TREM‐1) is thought to be critical for inflammatory signal amplification and involved in the development of atherosclerosis. TREM‐1 is significantly increased in patients with myocardial infarction. The aim of this study was to investigate the association between soluble TREM‐1 (sTREM‐1) and mortality and cardiovascular events in patients with acute myocardial infarction. Methods and Results We included 838 consecutive patients with acute myocardial infarction from October 7, 2012 to December 5, 2014. Blood samples were collected from patients with acute myocardial infarction immediately after diagnosis. During follow‐up, 88 patients died, and 180 patients reached the combined end points of major adverse cardiovascular event (MACE). Patients with high sTREM‐1 (higher than the median) had increased risk of all‐cause mortality and MACE compared with those with low sTREM‐1 (log‐rank test, P
- Published
- 2018
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