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Medical waste recycling and treatment has gradually drawn concerns from the whole society, as the amount of medical waste generated is increasing dramatically, especially during the pandemic of COVID-19. To tackle the emerging challenges, this study designs a reverse logistics system architecture with three modules, i.e., medical waste classification & monitoring module, temporary storage & disposal site (disposal site for short) selection module, as well as route optimization module. This overall solution design won the Grand Prize of the “YUNFENG CUP” China National Contest on Green Supply and Reverse Logistics Design ranking 1 st . This paper focuses on the design of the route optimization module. In this module, a route optimization problem is designed considering transportation costs and multiple risk costs (e.g., environment risk, population risk, property risk, and other accident-related risks). The Analytic Hierarchy Process is employed to determine the weights for each risk element, and a customized genetic algorithm is developed to solve the route optimization problem. A case study under the COVID-19 pandemic is further provided to verify the proposed model. Limited by length, detailed descriptions of the whole system and the other modules can be found at https://shorturl.at/cdY59., Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public., Transport and Planning

With social progress and the development of modern medical technology, the amount of medical waste generated is increasing dramatically. The problem of medical waste recycling and treatment has gradually drawn concerns from the whole society. The sudden outbreak of the COVID-19 epidemic further brought new challenges. To tackle the challenges, this study proposes a reverse logistics system architecture with three modules, i.e., medical waste classification & monitoring module, temporary storage & disposal site (disposal site for short) selection module, as well as route optimization module. This overall solution design won the Grand Prize of the “YUNFENG CUP” China National Contest on Green Supply and Reverse Logistics Design ranking 1 st . This paper focuses on the description of architectural design and the module on site selection. Specifically, regarding system architecture, a framework diagram is provided, together with brief descriptions of the three proposed modules and a case study under the COVID-19 epidemic with the customized model. Regarding the disposal site selection module, a multi-objective optimization model is developed, and considering different types of waste collection sites (i.e., prioritized large collection sites and common collection sites), a hierarchical solution method is developed employing linear programming and K-means clustering algorithms sequentially. The proposed site selection method is verified with a case study using real-world data, and compared with the baseline, it can immensely reduce the daily operational costs and working time. Limited by length, detailed descriptions of the whole system as well as the remaining medical waste classification & monitoring module and route optimization module can be found at https://shorturl.at/cdY59., Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public., Transport and Planning