21,499 results on '"Xu Min"'
Search Results
2. Comparative analysis of organophosphorus versus carbamate pesticide poisoning: a case study
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Xia Jia-ding, Wang Hui, Hua Li-wei, Xu Min, Zheng Xin, and Zhang Kun
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acetylcholinesterase ,carbamate ,carbofuran ,cholinergic crisis ,dichlorvos ,intensive care ,organophosphates ,acetilkolinesteraza ,diklorvos ,intenzivna skrb ,karbamat ,karbofuran ,kolinergična kriza ,organofosfati ,Toxicology. Poisons ,RA1190-1270 - Abstract
Organophosphorus poisoning is a critical condition that can cause central nervous system depression, respiratory failure, and death early on. As its clinical manifestations closely resemble those of carbamate pesticide poisoning, the aim of this case study is to present a case of misdiagnosis, initially identifying carbofuran poisoning as organophosphate in a patient suspect of a heatstroke. We also present a case of intentional self-poisoning with organophosphate dichlorvos to underline the likelihood of pesticide poisoning in patients exhibiting acute cholinergic symptoms when the ingested substance is not known. In such cases, empirical treatment with atropine and oxime can be started pending timely differential diagnosis to adjust treatment as necessary.
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- 2024
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3. Immature central tumor tertiary lymphoid structures are associated with better prognosis in non-small cell lung cancer
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Deng Xiaoxu, Xu Min, and Cao Chengcheng
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Non-small cell lung cancer ,Tertiary lymphoid structure ,CD8 ,Prognosis ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background & aims Tertiary lymphoid structures (TLSs) are predictive biomarkers of favorable clinical outcomes and immunotherapy response in several solid malignancies, including non-small cell lung cancer (NSCLC). However, the relationship between TLSs and NSCLC prognosis has not been eludicated from the aspects of location, density, and maturity. This study aimed to investigate the clinicopathological and prognostic significance of TLSs in NSCLC. Methods A collection of 151 resected pulmonary nodules in patients with NSCLC was retrospectively analyzed. Two experienced pathologists reviewed hematoxylin-eosin (H&E) slides and assessed TLS scores at different anatomic subregions. Then, we analyzed their correlation with clinicopathologic parameters and CD8 staining intensity and assessed multiple clinicopathological factors affecting patient prognosis. Results CD8 expression was correlated with total (TLS-CT) (P = 0.000), aggregates (Agg) (TLS-CT) (P = 0.001), follicles (FOL)-I (TLS-CT) (P = 0.025), and TLS(overall) (P = 0.013). TLS scores in the central tumor (CT) and invasion margin (IM) areas were negatively correlated with distant metastasis and Union for International Cancer Control (UICC) stage in NSCLC patients, while TLS score in the CT area was positively correlated with CD8 expression. TLS (overall), Agg (TLS-CT), and FOL-I (TLS-CT) were positively correlated with distant metastasis, UICC stage, and CD8 expression in NSCLC patients. Agg (TLS-IM) was positively correlated with distant metastasis and UICC stage. FOL-I (TLS-IM) was positively correlated with UICC stage. FOL-II (TLS-IM) was positively correlated with distant metastasis (P
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- 2024
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4. Construction of ethical cooperative review mode based on medical union
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ZHOU Ren, CAI Mingmin, XIE Bo, XU Min, and WANG Huiping
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medical union ,clinical research ,ethical review ,cooperative mode ,standard operation procedure ,Medicine - Abstract
With the rapid development of biomedical science and technology in China, the number of clinical research projects is increasing rapidly, which is accompanied by ethical challenges. In recent years, a number of regional ethics committees have been established in China, and some experience has been gained in regional ethical review, but there is a certain difficulty in implementing it. In response to the difficulties in regional ethical review, the ethical cooperative review mode of medical union with the leading units as the core has been established based on the experience of foreign regional ethical review and the characteristics of the medical consortium structures that have been widely established in the county-level hospitals and prefecture level tertiary hospitals in Jiangsu region. It is expected to give full play to the flexible advantages of regional ethics committees by radiating and promoting the ethical review ability of medical union.
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- 2023
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5. Digital technology-enabled non-heritage spatial landscape design in the context of rural revitalization
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Xu Min
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digital technology ,intangible cultural heritage ,spatial landscape design ,rural revitalization ,97n80 ,Mathematics ,QA1-939 - Abstract
The development of digital technology provides new impetus and methods for rural revitalization in terms of spatial landscape design for intangible cultural heritage (ICH). Digital technology can effectively preserve and transmit cultural heritage and promote the sustainable development of local culture and economy by enhancing its experiential and interactive nature. As an essential carrier of non-heritage culture, rural areas face contradictions between tradition and modernity, conservation and development. In-depth study is needed to understand how to use digital technology to promote rural revitalization while protecting NRLs. This study explores how digital technology can assist non-heritage spatial landscape design in rural revitalization to promote cultural inheritance and regional development. This paper analyzes the landscape design of 18 digitized non-heritage spaces with local characteristics quantitatively and qualitatively. The integration of NRL spaces increased by 30% on average, while visitor satisfaction increased by 25%. At the same time, the inheritance and promotion of local culture were enhanced by 40%. Through the application of digital technology, the recognition, guidance, culture, and diversity of the NRM space have significantly improved. Digital technology enhances the design quality and experience of non-heritage spaces and promotes the development of cultural tourism and economic revitalization in rural areas. The study provides new perspectives and practical paths for protecting and utilizing non-heritage in the context of rural revitalization.
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- 2024
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6. Strategy for Guaranteeing Power Supply Security of China
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Rao Hong, Han Feng, Chen Zheng, Huang Guori, Wang Dan, Zhang Ye, Cai Wantong, Xu Min, Jiang Weiyong, and Zhou Baorong
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power security ,supply security ,carbon peaking and carbon neutrality ,new type of power system ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Electric power is vital for the national security, economy, and people’s livelihood of a country. Ensuring the stable and secure supply of electric power is crucial for achieving carbon peaking and carbon neutrality. Therefore, it is imperative to analyze the weaknesses and challenges of power supply security in China and construct a power supply guarantee system that adapts to the new era and facilitate high-quality economic development. Herein, the research progress of power security supply is reviewed, the current status of power supply in China is summarized, and the trend in power security supply in China during the 14th Five-Year period and for the medium and long terms is analyzed. Moreover, considering the recent power rationing incidents, the problems and challenges for power supply in China are summarized and analyzed. On this basis, the basic principles of adhering to security first, a low-carbon path, market-oriented reforms, and technological innovations are proposed, and a three-step roadmap for constructing a new power supply guarantee system is investigated. Furthermore, we propose the following suggestions: (1) enhancing China’s power supply guarantee capabilities to solidify its foundation for power supply security; (2) improving the intrinsic security of power supply by focusing on the demand side; (3) establishing a new-generation technical system for guaranteeing power supply security; and (4) optimizing the market system to construct a power security ecology participated by all.
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- 2023
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7. Microbial monitoring of urban drinking water in Jiangxi Province from 2016 to 2020
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LU Keke, HE Jiafen, FU Junjie, WU Hao, HE Wenxin, XU Min, LU Feibao, and JIANG Wenbin
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drinking water ,microorganism ,monitoring ,qualification rate ,city ,Medicine - Abstract
ObjectiveTo monitor the microbes in urban drinking water in Jiangxi from 2016 to 2020, to analyze the change in microbial qualification rate, and to provide a scientific basis for government decision-making.MethodsAccording to the Standard Examination Method for Drinking Water (GB/T 5750‒2006) and the Standards for Drinking Water Quality (GB 5749‒2006), the water samples were collected, tested and evaluated for hygienic safety. The chi-square test was used to compare the qualification rates among different water periods, water source types, water supply modes, water samples, treatment processes, and disinfection methods.ResultsA total of 10 584 water samples were collected and examined from 2016 to 2020,with a qualification rate of 97.72%. The qualified rate of the microbiological index increased gradually over the years. There was no statistically significant difference in the microbiological qualification rate of water samples monitored in different water periods (χ2=0.718,P=0.398), and the qualification rates were 97.85% and 97.60% in dry and abundant water periods respectively. There was a statistically significant difference in the qualification rates of water samples monitored in different water source types (χ2=79.560,P=0.398), with groundwater having a higher qualification rate of 98.83% than surface water (97.70%). The microbiological pass rate of water samples differed among different water supply methods (χ2=201.836,P
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- 2023
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8. Application Value and Research Progress of Human Microbiome in Sexual Assault Cases
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LIU Yang, XU Min-min, ZHANG Ya, LIU Shi-quan, YUAN Mei-qing, and JIA Zhen-Jun
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forensic medicine ,microbiology ,microbial genomics ,sexual assault ,body fluid ,review ,Medicine - Abstract
In recent years, sexual assault cases have been on the rise, seriously infringing the legitimate rights and interests of women and children, causing widespread concern in society. DNA evidence has become the key evidence to prove the facts in sexual assault cases, but lack of DNA evidence or only DNA evidence in some sexual assault cases leads to unclear facts and insufficient evidence. With the emergence of high-throughput sequencing technology and the development of bioinformatics and artificial intelligence, new progress has been made in the study of human microbiome. Researchers have begun to use human microbiome for difficult sexual assault cases indentification. This paper reviews the characteristics of human microbiome, and its application value in the inferences of the body fluid stain origin, the sexual assault method, the crime time, etc. In addition, the challenges faced by the application of the human microbiome in practical case handling, the solutions and future development potential are analyzed and prospected.
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- 2022
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9. Data-driven demand prediction based on integrated LSTM model
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HU Cong, XU Min, HONG Dehua, WANG Haixin, LIU Cuiling, and XUE Xiaoru
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integrated long short-term memory (lstm) algorithm ,demand elasticity ,data preprocessing ,power market ,incentive-based demand response ,data-driven ,Applications of electric power ,TK4001-4102 - Abstract
The flexibility of the power grid can be significantly promoted by the participation of power customers in dispatch. However, as the uncertainty of customer behavior,the development of demand response services is limited. To solve this problem,the framework of incentive-based demand response is constructed in this paper. The way that load aggregators integrate demand-side resources to participate in the power market is elaborated. And the behavior of power customers responding to incentive policies is transformed into demand elasticity. Then,a data-driven demand elasticity prediction method based on the integrated long short-term memory (LSTM) is proposed. Meanwhile,to improve the performance of the prediction model,the original data is smoothed and scaled,and the weight coefficients of the loss function are added. The simulation results show that,compared with the traditional LSTM algorithm and the k-proximity prediction method,the average forecasting error with the proposed model for the demand elasticity is reduced by 5.33% and 28.8%,and mean absolute percentage error (MAPE) for the total load prediction is reduced by 2.06% and 3.09%. Additionally,based on integrated LSTM,the influence of smoothing and scaling data preprocessing on prediction accuracy is analyzed. The results show that the prediction accuracy can be significantly promoted by data preprocessing.
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- 2022
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10. Spatiotemporal Variation in Waterlogging and Thermal Stress to Cotton in Hubei Province
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MENG Huayue, WU Yuxiao, QIAN Long, LUO Yunying, CHEN Cheng, XU Min, and DENG Jingyao
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cotton ,field drainage ,rainstorms ,waterlogging stress ,heat stress ,Agriculture (General) ,S1-972 ,Irrigation engineering. Reclamation of wasteland. Drainage ,TC801-978 - Abstract
【Objective】 Waterlogging and thermal stress are two abiotic stresses faced by cotton production in central China. This paper analyzed the spatiotemporal variation in waterlogging (WL), thermal stress (HT), and waterlogging followed by thermal stress (WL-HT) to cotton in Hubei province. 【Method】 Daily precipitation and air temperatures were collected from 26 meteorological stations across the province to calculate the occurrence of WL, HT, WL-HT, as well as the conversion from WL to WL-HT at the seedling, budding, flowering and boll-filling stage, and the boll opening stage. Spatiotemporal variations of these events were calculated using the linear temporal trend method, the moving t-test and the inverse distance interpolation. 【Result】 The last six decades have seen a significant increase in WL (p30%. Huanggang was prone to both WL and WL-HT. In contrast, Xiangyang, Zhongxiang and Jingzhou had a low WL but high WL-HT. 【Conclusion】 Cotton production in Hubei province has seen an increase in waterlogging followed by high temperatures over the recent decade. Timely drainage at the flowering and boll-filling stage when temperature is high in the south-central, northwestern and northeastern province is essential to safeguarding cotton production there.
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- 2022
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11. The cation-π interaction in cysteine-rich domain of Smoothened is critical for its cholesterylation and function
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Kong Zekai, Xu Min, Zhang Yanqing, Huang Wenda, Zhao Xiaolu, Luo Jie, and Song Bao-Liang
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Hedgehog ,Smoothened ,cholesterylation ,cysteine-rich domain ,cation-π interaction ,Biochemistry ,QD415-436 ,Genetics ,QH426-470 - Abstract
The Hedgehog (Hh) signaling pathway is critical for embryonic development and tissue renewal. The G protein-coupled receptor (GPCR)-like protein Smoothened (SMO) is the central signal transducer in the Hh pathway. Cholesterol binds and then covalently links to the D95 residue of cysteine-rich domain (CRD) of human SMO. The cholesterylation of CRD is critical for SMO activation. SMO cholesterylation is a Ca2+-boosted autoreaction that requires the formation of an ester bond between the side chains of D95 and Y130 as an intermediate. It is unknown whether other residues of SMO are involved in the esterification between D95 and cholesterol. In this study, we find that the SMO-CRD(27–192) can undergo cholesterylation. In addition to D95 and Y130, the residues critical for cholesterol modification include Y85, T88, T90, W109, W119, K133, E160 and F166. T88, W109, W119 and F166 also seem to be involved in protein folding. Notably, we find that Y85 and K133 form a cation-π interaction whose disruption abolishes cholesterylation and ciliary localization of SMO. This study highlights the mechanism and function of cholesterol modification of SMO.
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- 2022
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12. Effect of ceramic particles on corrosion resistance of thermal sprayed stainless steel coating
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TANG Quan, ZHANG Suo-de, XU Min, and WANG Jian-qiang
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stainless steel coating ,high-velocity air fuel (hvaf) spraying ,ceramic particle ,corrosion resistance ,Materials of engineering and construction. Mechanics of materials ,TA401-492 - Abstract
The ceramic particles of different types and sizes reinforced stainless steel composite coatings were successfully prepared by high-velocity air fuel (HVAF) spraying technique. The effects of the types and sizes of ceramic particles on the hardness, porosity and corrosion resistance of the composite coating were systematically studied. The microstructure, hardness and corrosion behavior of stainless steel/ceramic particle composite coating were systematically characterized and analyzed by scanning electron microscope, automatic hardness tester, Image Pro Plus software and electrochemical workstation. The results show that the larger brown alumina (Al2O3) particles reinforced stainless steel composite coating has low porosity (0.7863%), high hardness (637HV0.1) and excellent corrosion resistance, and its self-corrosion potential is -454.14 mV and self-corrosion current density is 22.208 mA·cm-2. The fine silicon carbide (SiC) particles reinforced stainless steel composite coating also has a relatively high hardness (600HV0.1) and good corrosion resistance, and its self-corrosion potential is -463.68 mV and self-corrosion current density is 23.738 mA·cm-2.
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- 2021
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13. Y-CA-Net: A Convolutional Attention Based Network for Volumetric Medical Image Segmentation
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Sharif, Muhammad Hamza, Naseer, Muzammal, Yaqub, Mohammad, Xu, Min, and Guizani, Mohsen
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Recent attention-based volumetric segmentation (VS) methods have achieved remarkable performance in the medical domain which focuses on modeling long-range dependencies. However, for voxel-wise prediction tasks, discriminative local features are key components for the performance of the VS models which is missing in attention-based VS methods. Aiming at resolving this issue, we deliberately incorporate the convolutional encoder branch with transformer backbone to extract local and global features in a parallel manner and aggregate them in Cross Feature Mixer Module (CFMM) for better prediction of segmentation mask. Consequently, we observe that the derived model, Y-CT-Net, achieves competitive performance on multiple medical segmentation tasks. For example, on multi-organ segmentation, Y-CT-Net achieves an 82.4% dice score, surpassing well-tuned VS Transformer/CNN-like baselines UNETR/ResNet-3D by 2.9%/1.4%. With the success of Y-CT-Net, we extend this concept with hybrid attention models, that derived Y-CH-Net model, which brings a 3% improvement in terms of HD95 score for same segmentation task. The effectiveness of both models Y-CT-Net and Y-CH-Net verifies our hypothesis and motivates us to initiate the concept of Y-CA-Net, a versatile generic architecture based upon any two encoders and a decoder backbones, to fully exploit the complementary strengths of both convolution and attention mechanisms. Based on experimental results, we argue Y-CA-Net is a key player in achieving superior results for volumetric segmentation.
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- 2024
14. TransResNet: Integrating the Strengths of ViTs and CNNs for High Resolution Medical Image Segmentation via Feature Grafting
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Sharif, Muhammad Hamza, Demidov, Dmitry, Hanif, Asif, Yaqub, Mohammad, and Xu, Min
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
High-resolution images are preferable in medical imaging domain as they significantly improve the diagnostic capability of the underlying method. In particular, high resolution helps substantially in improving automatic image segmentation. However, most of the existing deep learning-based techniques for medical image segmentation are optimized for input images having small spatial dimensions and perform poorly on high-resolution images. To address this shortcoming, we propose a parallel-in-branch architecture called TransResNet, which incorporates Transformer and CNN in a parallel manner to extract features from multi-resolution images independently. In TransResNet, we introduce Cross Grafting Module (CGM), which generates the grafted features, enriched in both global semantic and low-level spatial details, by combining the feature maps from Transformer and CNN branches through fusion and self-attention mechanism. Moreover, we use these grafted features in the decoding process, increasing the information flow for better prediction of the segmentation mask. Extensive experiments on ten datasets demonstrate that TransResNet achieves either state-of-the-art or competitive results on several segmentation tasks, including skin lesion, retinal vessel, and polyp segmentation. The source code and pre-trained models are available at https://github.com/Sharifmhamza/TransResNet., Comment: The 33rd British Machine Vision Conference 2022
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- 2024
15. Multimodal Generalized Category Discovery
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Su, Yuchang, Zhou, Renping, Huang, Siyu, Li, Xingjian, Wang, Tianyang, Wang, Ziyue, and Xu, Min
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning - Abstract
Generalized Category Discovery (GCD) aims to classify inputs into both known and novel categories, a task crucial for open-world scientific discoveries. However, current GCD methods are limited to unimodal data, overlooking the inherently multimodal nature of most real-world data. In this work, we extend GCD to a multimodal setting, where inputs from different modalities provide richer and complementary information. Through theoretical analysis and empirical validation, we identify that the key challenge in multimodal GCD lies in effectively aligning heterogeneous information across modalities. To address this, we propose MM-GCD, a novel framework that aligns both the feature and output spaces of different modalities using contrastive learning and distillation techniques. MM-GCD achieves new state-of-the-art performance on the UPMC-Food101 and N24News datasets, surpassing previous methods by 11.5\% and 4.7\%, respectively.
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- 2024
16. Linear Network Coding for Robust Function Computation and Its Applications in Distributed Computing
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Wei, Hengjia, Xu, Min, and Ge, Gennian
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Computer Science - Information Theory - Abstract
We investigate linear network coding in the context of robust function computation, where a sink node is tasked with computing a target function of messages generated at multiple source nodes. In a previous work, a new distance measure was introduced to evaluate the error tolerance of a linear network code for function computation, along with a Singleton-like bound for this distance. In this paper, we first present a minimum distance decoder for these linear network codes. We then focus on the sum function and the identity function, showing that in any directed acyclic network there are two classes of linear network codes for these target functions, respectively, that attain the Singleton-like bound. Additionally, we explore the application of these codes in distributed computing and design a distributed gradient coding scheme in a heterogeneous setting, optimizing the trade-off between straggler tolerance, computation cost, and communication cost. This scheme can also defend against Byzantine attacks.
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- 2024
17. High-Fidelity Data-Driven Dynamics Model for Reinforcement Learning-based Magnetic Control in HL-3 Tokamak
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Wu, Niannian, Yang, Zongyu, Li, Rongpeng, Wei, Ning, Chen, Yihang, Dong, Qianyun, Li, Jiyuan, Zheng, Guohui, Gong, Xinwen, Gao, Feng, Li, Bo, Xu, Min, Zhao, Zhifeng, and Zhong, Wulyu
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Physics - Plasma Physics - Abstract
The drive to control tokamaks, a prominent technology in nuclear fusion, is essential due to its potential to provide a virtually unlimited source of clean energy. Reinforcement learning (RL) promises improved flexibility to manage the intricate and non-linear dynamics of the plasma encapsulated in a tokamak. However, RL typically requires substantial interaction with a simulator capable of accurately evolving the high-dimensional plasma state. Compared to first-principle-based simulators, whose intense computations lead to sluggish RL training, we devise an effective method to acquire a fully data-driven simulator, by mitigating the arising compounding error issue due to the underlying autoregressive nature. With high accuracy and appealing extrapolation capability, this high-fidelity dynamics model subsequently enables the rapid training of a qualified RL agent to directly generate engineering-reasonable magnetic coil commands, aiming at the desired long-term targets of plasma current and last closed flux surface. Together with a surrogate magnetic equilibrium reconstruction model EFITNN, the RL agent successfully maintains a $100$-ms, $1$ kHz trajectory control with accurate waveform tracking on the HL-3 tokamak. Furthermore, it also demonstrates the feasibility of zero-shot adaptation to changed triangularity targets, confirming the robustness of the developed data-driven dynamics model. Our work underscores the advantage of fully data-driven dynamics models in yielding RL-based trajectory control policies at a sufficiently fast pace, an anticipated engineering requirement in daily discharge practices for the upcoming ITER device.
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- 2024
18. Federated Prototype-based Contrastive Learning for Privacy-Preserving Cross-domain Recommendation
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Wang, Li, Zhang, Quangui, Sang, Lei, Wu, Qiang, and Xu, Min
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Computer Science - Information Retrieval - Abstract
Cross-domain recommendation (CDR) aims to improve recommendation accuracy in sparse domains by transferring knowledge from data-rich domains. However, existing CDR methods often assume the availability of user-item interaction data across domains, overlooking user privacy concerns. Furthermore, these methods suffer from performance degradation in scenarios with sparse overlapping users, as they typically depend on a large number of fully shared users for effective knowledge transfer. To address these challenges, we propose a Federated Prototype-based Contrastive Learning (CL) method for Privacy-Preserving CDR, named FedPCL-CDR. This approach utilizes non-overlapping user information and prototypes to improve multi-domain performance while protecting user privacy. FedPCL-CDR comprises two modules: local domain (client) learning and global server aggregation. In the local domain, FedPCL-CDR clusters all user data to learn representative prototypes, effectively utilizing non-overlapping user information and addressing the sparse overlapping user issue. It then facilitates knowledge transfer by employing both local and global prototypes returned from the server in a CL manner. Simultaneously, the global server aggregates representative prototypes from local domains to learn both local and global prototypes. The combination of prototypes and federated learning (FL) ensures that sensitive user data remains decentralized, with only prototypes being shared across domains, thereby protecting user privacy. Extensive experiments on four CDR tasks using two real-world datasets demonstrate that FedPCL-CDR outperforms the state-of-the-art baselines.
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- 2024
19. A Learnable Agent Collaboration Network Framework for Personalized Multimodal AI Search Engine
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Shi, Yunxiao, Xu, Min, Zhang, Haimin, Zi, Xing, and Wu, Qiang
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Computer Science - Information Retrieval ,Computer Science - Multiagent Systems - Abstract
Large language models (LLMs) and retrieval-augmented generation (RAG) techniques have revolutionized traditional information access, enabling AI agent to search and summarize information on behalf of users during dynamic dialogues. Despite their potential, current AI search engines exhibit considerable room for improvement in several critical areas. These areas include the support for multimodal information, the delivery of personalized responses, the capability to logically answer complex questions, and the facilitation of more flexible interactions. This paper proposes a novel AI Search Engine framework called the Agent Collaboration Network (ACN). The ACN framework consists of multiple specialized agents working collaboratively, each with distinct roles such as Account Manager, Solution Strategist, Information Manager, and Content Creator. This framework integrates mechanisms for picture content understanding, user profile tracking, and online evolution, enhancing the AI search engine's response quality, personalization, and interactivity. A highlight of the ACN is the introduction of a Reflective Forward Optimization method (RFO), which supports the online synergistic adjustment among agents. This feature endows the ACN with online learning capabilities, ensuring that the system has strong interactive flexibility and can promptly adapt to user feedback. This learning method may also serve as an optimization approach for agent-based systems, potentially influencing other domains of agent applications., Comment: ACMMM 2024 MMGR WORKSHOP
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- 2024
20. A non-destructive channel stress characterization for gate-all-around nanosheet transistors by confocal Raman methodology
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Huang Ziqiang, Liu Tao, Yang Jingwen, Sun Xin, Chen Kun, Wang Dawei, Hu Hailong, Xu Min, Wang Chen, Xu Saisheng, and Zhang David Wei
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non-destructive characterization ,channel stress ,gate all around (GAA) ,confocal Raman ,Science ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Non-destructive stress characterization is essential for gate-all-around (GAA) nanosheet (NS) transistors technology, while it is a big challenge to be realized on nanometer-sized GAA devices by using traditional Micro-Raman spectroscopy due to its light spot far exceeding the device. In this work, a non-destructive stress characterization methodology of confocal Raman spectroscopy was proposed and performed for GAANS device fabrication. Channel stress evolution along the fabrication process was successfully characterized by designing high-density NS array and analyzing the linear scanned spectra in different structures. The related mechanism of stress evolution was systematically studied by Sentaurus process simulation. Additionally, applying this methodology on detecting the bending of suspended NS after channel release process was demonstrated. Therefore, this work might provide a promising solution to realize in-line characterization of channel stress in GAA NS transistors and process monitor of NS channel integrity.
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- 2022
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21. Research on New Energy Generation Scheduling for Grid Security and Scheduling Fairness
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GUO Yuanping, XU Min, GUO Zuogang, TAN Yingjie, and LI Yi
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safety constraints ,dispatch fairness ,generation scheduling ,output limitation ,Energy industries. Energy policy. Fuel trade ,HD9502-9502.5 - Abstract
[Introduction] With incessant grid-connection of wind farms and photovoltaic power stations, the development of regional power grid structure cannot keep pace with the growth rate of new energy unit capacity, characteristics of multi-energy mix and hierarchical features of section bring difficulties to the formulation of day-ahead generation scheduling, for this reason, a method for multi-level and multi-energy day-ahead generation scheduling considering the safety constraint of the section and the fairness of dispatch was proposed. [Method] This paper presented a depth-first search for the restricted section, and proposed an output limitation allocation strategy based on information entropy. A fairness calculation method was constructed by using the concept of information entropy in economics to guide the quantitative indicators for evaluating scheduling fairness. [Result] Under the circumstances of ensuring that the cross-sectional current is close to the stability limit, the active power of each power plant is distributed reasonably and equitably, thereby realizes the full utilization of wind and solar resources. [Conclusion] Through a practical example of a regional power grid, it is proved that this method can solve the existing problems in new energy day-ahead generation scheduling and has good practical application value.
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- 2021
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22. miR-380-5p facilitates NRF2 and attenuates cerebral ischemia/reperfusion injury-induced neuronal cell death by directly targeting BACH1
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Wang Yibiao and Xu Min
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mir-380-5p ,nrf2 ,cerebral ischemia/reperfusion injury ,neuronal cell death ,bach1 ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
This study aimed to explore the role of miR-380-5p in cerebral ischemia/reperfusion (CIR) injury-induced neuronal cell death and the potential signaling pathway involved.
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- 2021
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23. Using DRAINMOD to Simulate the Impact of Irrigation and Drainage on Reaction and Movement of Water and Nitrogen in Paddy Field
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XIE Yangcun, XU Min, GAO Shikai, and Shen Lianqi
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rice ,change in water and nitrogen ,drainmod model ,sensitivity analysis ,controlled irrigation and drainage ,Agriculture (General) ,S1-972 ,Irrigation engineering. Reclamation of wasteland. Drainage ,TC801-978 - Abstract
【Background】 Nonpoint source pollution from managed ecosystems is a major environmental concern in many countries. Using models to simulate contaminant movement in agricultural systems under different managements can help improve water management and reduce nitrogen loss. 【Objective】 The purpose of this paper is to study the movement and reaction of water and nitrogen in paddy field under different irrigation and drainage, with a view to improve water conservation and reduce gas emission from rice production in southern China. 【Method】 We used the DRAINMOD model to simulate water flow and nitrogen transport; the sensitivity of the simulated results to its parameters was quantified using the Morris analysis. 【Result】 Horizontal saturated hydraulic conductivity in the 20~40 cm soil layer affected the simulation results most; diffusion coefficient, denitrification and nitrification parameters, decomposition of soil organic matter all had a significant impact on the simulated nitrogen dynamics. The DRAINMOD model was able to simulate water and nitrogen dynamics in soil under different irrigations and drainages, and the difference between the simulated and measured drainage and irrigation amounts and the total load of nitrogen runoff was less than 11%. Compared with traditional irrigation and drainage, controlled irrigation and drainage reduced drainage amount by 33.0%~72.6%, irrigation amount by 9.7%~37.1%, ammonium runoff load by 43.6%~45.0%, and nitrate runoff load by 29.8%~53.1%. 【Conclusion】 Controlled irrigation and drainage can effectively reduce gas emission, drainage and nitrogen loss from the paddy field, and the DRAINMOD model is able to simulate water flow and contaminant transport in paddy fields under different irrigation and drainage managements.
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- 2021
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24. GPR37 promotes the malignancy of lung adenocarcinoma via TGF-β/Smad pathway
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Wang Jian, Xu Min, Li Dan-Dan, Abudukelimu Wujikenayi, and Zhou Xiu-Hong
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lung adenocarcinoma ,gpr37 ,tgf-β/smad pathway ,Medicine - Abstract
This paper aimed to research the function and in-depth mechanism of GPR37 in lung adenocarcinoma (LUAD). Herein, based on TCGA and Oncomine databases, we revealed that GPR37 was expressed at high levels in LUAD, and upregulation of GPR37 was related to the poor outcomes. Furthermore, biological function experiments in vitro were utilized to assess whether GPR37 impacts malignant phenotype of LUAD cells. Gain- or loss-of-function assays indicated that the upregulation of GPR37 contributed to improving the proliferation, migration, and invasion of LUAD cells in vitro, while knockdown of GPR37 can inhibit the malignant biological behaviors. Then, we found that depletion of GPR37 resulted in a decrease in the expression of TGF-β1 as well as the extents of Smad2 and Smad3 phosphorylation, while overexpression of GPR37 presented opposite outcomes. Altogether, our findings indicated that GPR37 is a potential oncogene of LUAD, and its promoting effects on the malignant progression of LUAD may be realized via TGF-β/Smad pathway.
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- 2020
- Full Text
- View/download PDF
25. Federated User Preference Modeling for Privacy-Preserving Cross-Domain Recommendation
- Author
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Wang, Li, Wang, Shoujin, Zhang, Quangui, Wu, Qiang, and Xu, Min
- Subjects
Computer Science - Information Retrieval - Abstract
Cross-domain recommendation (CDR) aims to address the data-sparsity problem by transferring knowledge across domains. Existing CDR methods generally assume that the user-item interaction data is shareable between domains, which leads to privacy leakage. Recently, some privacy-preserving CDR (PPCDR) models have been proposed to solve this problem. However, they primarily transfer simple representations learned only from user-item interaction histories, overlooking other useful side information, leading to inaccurate user preferences. Additionally, they transfer differentially private user-item interaction matrices or embeddings across domains to protect privacy. However, these methods offer limited privacy protection, as attackers may exploit external information to infer the original data. To address these challenges, we propose a novel Federated User Preference Modeling (FUPM) framework. In FUPM, first, a novel comprehensive preference exploration module is proposed to learn users' comprehensive preferences from both interaction data and additional data including review texts and potentially positive items. Next, a private preference transfer module is designed to first learn differentially private local and global prototypes, and then privately transfer the global prototypes using a federated learning strategy. These prototypes are generalized representations of user groups, making it difficult for attackers to infer individual information. Extensive experiments on four CDR tasks conducted on the Amazon and Douban datasets validate the superiority of FUPM over SOTA baselines. Code is available at https://github.com/Lili1013/FUPM.
- Published
- 2024
26. Beyond KAN: Introducing KarSein for Adaptive High-Order Feature Interaction Modeling in CTR Prediction
- Author
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Shi, Yunxiao, Xu, Wujiang, Jin, Mingyu, Zhang, Haimin, Wu, Qiang, Zhang, Yongfeng, and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Information Retrieval - Abstract
Modeling feature interactions is crucial for click-through rate (CTR) prediction, particularly when it comes to high-order explicit interactions. Traditional methods struggle with this task because they often predefine a maximum interaction order, which relies heavily on prior knowledge and can limit the model's effectiveness. Additionally, modeling high-order interactions typically leads to increased computational costs. Therefore, the challenge lies in adaptively modeling high-order feature interactions while maintaining efficiency. To address this issue, we introduce Kolmogorov-Arnold Represented Sparse Efficient Interaction Network (KarSein), designed to optimize both predictive accuracy and computational efficiency. We firstly identify limitations of directly applying Kolmogorov-Arnold Networks (KAN) to CTR and then introduce KarSein to overcome these issues. It features a novel architecture that reduces the computational costs of KAN and supports embedding vectors as feature inputs. Additionally, KarSein employs guided symbolic regression to address the challenge of KAN in spontaneously learning multiplicative relationships. Extensive experiments demonstrate KarSein's superior performance, achieving significant predictive accuracy with minimal computational overhead. Furthermore, KarSein maintains strong global explainability while enabling the removal of redundant features, resulting in a sparse network structure. These advantages also position KarSein as a promising method for efficient inference., Comment: KarSein for CTR
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- 2024
27. Unsupervised Part Discovery via Dual Representation Alignment
- Author
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Xia, Jiahao, Huang, Wenjian, Xu, Min, Zhang, Jianguo, Zhang, Haimin, Sheng, Ziyu, and Xu, Dong
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
Object parts serve as crucial intermediate representations in various downstream tasks, but part-level representation learning still has not received as much attention as other vision tasks. Previous research has established that Vision Transformer can learn instance-level attention without labels, extracting high-quality instance-level representations for boosting downstream tasks. In this paper, we achieve unsupervised part-specific attention learning using a novel paradigm and further employ the part representations to improve part discovery performance. Specifically, paired images are generated from the same image with different geometric transformations, and multiple part representations are extracted from these paired images using a novel module, named PartFormer. These part representations from the paired images are then exchanged to improve geometric transformation invariance. Subsequently, the part representations are aligned with the feature map extracted by a feature map encoder, achieving high similarity with the pixel representations of the corresponding part regions and low similarity in irrelevant regions. Finally, the geometric and semantic constraints are applied to the part representations through the intermediate results in alignment for part-specific attention learning, encouraging the PartFormer to focus locally and the part representations to explicitly include the information of the corresponding parts. Moreover, the aligned part representations can further serve as a series of reliable detectors in the testing phase, predicting pixel masks for part discovery. Extensive experiments are carried out on four widely used datasets, and our results demonstrate that the proposed method achieves competitive performance and robustness due to its part-specific attention., Comment: Accepted by TPAMI-2024
- Published
- 2024
28. Cross-Domain Learning for Video Anomaly Detection with Limited Supervision
- Author
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Jain, Yashika, Dabouei, Ali, and Xu, Min
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
Video Anomaly Detection (VAD) automates the identification of unusual events, such as security threats in surveillance videos. In real-world applications, VAD models must effectively operate in cross-domain settings, identifying rare anomalies and scenarios not well-represented in the training data. However, existing cross-domain VAD methods focus on unsupervised learning, resulting in performance that falls short of real-world expectations. Since acquiring weak supervision, i.e., video-level labels, for the source domain is cost-effective, we conjecture that combining it with external unlabeled data has notable potential to enhance cross-domain performance. To this end, we introduce a novel weakly-supervised framework for Cross-Domain Learning (CDL) in VAD that incorporates external data during training by estimating its prediction bias and adaptively minimizing that using the predicted uncertainty. We demonstrate the effectiveness of the proposed CDL framework through comprehensive experiments conducted in various configurations on two large-scale VAD datasets: UCF-Crime and XD-Violence. Our method significantly surpasses the state-of-the-art works in cross-domain evaluations, achieving an average absolute improvement of 19.6% on UCF-Crime and 12.87% on XD-Violence.
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- 2024
29. Medical Graph RAG: Towards Safe Medical Large Language Model via Graph Retrieval-Augmented Generation
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Wu, Junde, Zhu, Jiayuan, Qi, Yunli, Chen, Jingkun, Xu, Min, Menolascina, Filippo, and Grau, Vicente
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Computer Science - Computer Vision and Pattern Recognition - Abstract
We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating evidence-based medical responses, thereby improving safety and reliability when handling private medical data. Graph-based RAG (GraphRAG) leverages LLMs to organize RAG data into graphs, showing strong potential for gaining holistic insights from long-form documents. However, its standard implementation is overly complex for general use and lacks the ability to generate evidence-based responses, limiting its effectiveness in the medical field. To extend the capabilities of GraphRAG to the medical domain, we propose unique Triple Graph Construction and U-Retrieval techniques over it. In our graph construction, we create a triple-linked structure that connects user documents to credible medical sources and controlled vocabularies. In the retrieval process, we propose U-Retrieval which combines Top-down Precise Retrieval with Bottom-up Response Refinement to balance global context awareness with precise indexing. These effort enable both source information retrieval and comprehensive response generation. Our approach is validated on 9 medical Q\&A benchmarks, 2 health fact-checking benchmarks, and one collected dataset testing long-form generation. The results show that MedGraphRAG consistently outperforms state-of-the-art models across all benchmarks, while also ensuring that responses include credible source documentation and definitions. Our code is released at: https://github.com/MedicineToken/Medical-Graph-RAG.
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- 2024
30. Enhancing Retrieval and Managing Retrieval: A Four-Module Synergy for Improved Quality and Efficiency in RAG Systems
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Shi, Yunxiao, Zi, Xing, Shi, Zijing, Zhang, Haimin, Wu, Qiang, and Xu, Min
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence - Abstract
Retrieval-augmented generation (RAG) techniques leverage the in-context learning capabilities of large language models (LLMs) to produce more accurate and relevant responses. Originating from the simple 'retrieve-then-read' approach, the RAG framework has evolved into a highly flexible and modular paradigm. A critical component, the Query Rewriter module, enhances knowledge retrieval by generating a search-friendly query. This method aligns input questions more closely with the knowledge base. Our research identifies opportunities to enhance the Query Rewriter module to Query Rewriter+ by generating multiple queries to overcome the Information Plateaus associated with a single query and by rewriting questions to eliminate Ambiguity, thereby clarifying the underlying intent. We also find that current RAG systems exhibit issues with Irrelevant Knowledge; to overcome this, we propose the Knowledge Filter. These two modules are both based on the instruction-tuned Gemma-2B model, which together enhance response quality. The final identified issue is Redundant Retrieval; we introduce the Memory Knowledge Reservoir and the Retriever Trigger to solve this. The former supports the dynamic expansion of the RAG system's knowledge base in a parameter-free manner, while the latter optimizes the cost for accessing external knowledge, thereby improving resource utilization and response efficiency. These four RAG modules synergistically improve the response quality and efficiency of the RAG system. The effectiveness of these modules has been validated through experiments and ablation studies across six common QA datasets. The source code can be accessed at https://github.com/Ancientshi/ERM4., Comment: ECAI2024 #1304
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- 2024
31. ISPO: An Integrated Ontology of Symptom Phenotypes for Semantic Integration of Traditional Chinese Medical Data
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Shu, Zixin, Hua, Rui, Yan, Dengying, Lu, Chenxia, Xu, Ning, Li, Jun, Zhu, Hui, Zhang, Jia, Zhao, Dan, Hui, Chenyang, Ye, Junqiu, Liao, Chu, Hao, Qi, Ye, Wen, Luo, Cheng, Wang, Xinyan, Cheng, Chuang, Li, Xiaodong, Liu, Baoyan, Zhou, Xiaji, Zhang, Runshun, Xu, Min, and Zhou, Xuezhong
- Subjects
Computer Science - Computation and Language - Abstract
Symptom phenotypes are one of the key types of manifestations for diagnosis and treatment of various disease conditions. However, the diversity of symptom terminologies is one of the major obstacles hindering the analysis and knowledge sharing of various types of symptom-related medical data particularly in the fields of Traditional Chinese Medicine (TCM). Objective: This study aimed to construct an Integrated Ontology of symptom phenotypes (ISPO) to support the data mining of Chinese EMRs and real-world study in TCM field. Methods: To construct an integrated ontology of symptom phenotypes (ISPO), we manually annotated classical TCM textbooks and large-scale Chinese electronic medical records (EMRs) to collect symptom terms with support from a medical text annotation system. Furthermore, to facilitate the semantic interoperability between different terminologies, we incorporated public available biomedical vocabularies by manual mapping between Chinese terms and English terms with cross-references to source vocabularies. In addition, we evaluated the ISPO using independent clinical EMRs to provide a high-usable medical ontology for clinical data analysis. Results: By integrating 78,696 inpatient cases of EMRs, 5 biomedical vocabularies, 21 TCM books and dictionaries, ISPO provides 3,147 concepts, 23,475 terms, and 55,552 definition or contextual texts. Adhering to the taxonomical structure of the related anatomical systems of symptom phenotypes, ISPO provides 12 top-level categories and 79 middle-level sub-categories. The validation of data analysis showed the ISPO has a coverage rate of 95.35%, 98.53% and 92.66% for symptom terms with occurrence rates of 0.5% in additional three independent curated clinical datasets, which can demonstrate the significant value of ISPO in mapping clinical terms to ontologies., Comment: 39 pages, 6 figures, 6 tables
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- 2024
32. Training-free CryoET Tomogram Segmentation
- Author
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Zhao, Yizhou, Bian, Hengwei, Mu, Michael, Uddin, Mostofa R., Li, Zhenyang, Li, Xiang, Wang, Tianyang, and Xu, Min
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Quantitative Biology - Quantitative Methods ,Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
Cryogenic Electron Tomography (CryoET) is a useful imaging technology in structural biology that is hindered by its need for manual annotations, especially in particle picking. Recent works have endeavored to remedy this issue with few-shot learning or contrastive learning techniques. However, supervised training is still inevitable for them. We instead choose to leverage the power of existing 2D foundation models and present a novel, training-free framework, CryoSAM. In addition to prompt-based single-particle instance segmentation, our approach can automatically search for similar features, facilitating full tomogram semantic segmentation with only one prompt. CryoSAM is composed of two major parts: 1) a prompt-based 3D segmentation system that uses prompts to complete single-particle instance segmentation recursively with Cross-Plane Self-Prompting, and 2) a Hierarchical Feature Matching mechanism that efficiently matches relevant features with extracted tomogram features. They collaborate to enable the segmentation of all particles of one category with just one particle-specific prompt. Our experiments show that CryoSAM outperforms existing works by a significant margin and requires even fewer annotations in particle picking. Further visualizations demonstrate its ability when dealing with full tomogram segmentation for various subcellular structures. Our code is available at: https://github.com/xulabs/aitom, Comment: This preprint has not undergone peer review or any post-submission improvements or corrections. The Version of Record of this contribution will be published in MICCAI 2024
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- 2024
33. Improving Knowledge Distillation in Transfer Learning with Layer-wise Learning Rates
- Author
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Kokane, Shirley, Uddin, Mostofa Rafid, and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Transfer learning methods start performing poorly when the complexity of the learning task is increased. Most of these methods calculate the cumulative differences of all the matched features and then use them to back-propagate that loss through all the layers. Contrary to these methods, in this work, we propose a novel layer-wise learning scheme that adjusts learning parameters per layer as a function of the differences in the Jacobian/Attention/Hessian of the output activations w.r.t. the network parameters. We applied this novel scheme for attention map-based and derivative-based (first and second order) transfer learning methods. We received improved learning performance and stability against a wide range of datasets. From extensive experimental evaluation, we observed that the performance boost achieved by our method becomes more significant with the increasing difficulty of the learning task.
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- 2024
34. Differential Encoding for Improved Representation Learning over Graphs
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Zhang, Haimin, Xia, Jiahao, and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Social and Information Networks - Abstract
Combining the message-passing paradigm with the global attention mechanism has emerged as an effective framework for learning over graphs. The message-passing paradigm and the global attention mechanism fundamentally generate node embeddings based on information aggregated from a node's local neighborhood or from the whole graph. The most basic and commonly used aggregation approach is to take the sum of information from a node's local neighbourhood or from the whole graph. However, it is unknown if the dominant information is from a node itself or from the node's neighbours (or the rest of the graph nodes). Therefore, there exists information lost at each layer of embedding generation, and this information lost could be accumulated and become more serious when more layers are used in the model. In this paper, we present a differential encoding method to address the issue of information lost. The idea of our method is to encode the differential representation between the information from a node's neighbours (or the rest of the graph nodes) and that from the node itself. The obtained differential encoding is then combined with the original aggregated local or global representation to generate the updated node embedding. By integrating differential encodings, the representational ability of generated node embeddings is improved. The differential encoding method is empirically evaluated on different graph tasks on seven benchmark datasets. The results show that it is a general method that improves the message-passing update and the global attention update, advancing the state-of-the-art performance for graph representation learning on these datasets.
- Published
- 2024
35. HGTDP-DTA: Hybrid Graph-Transformer with Dynamic Prompt for Drug-Target Binding Affinity Prediction
- Author
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Xiao, Xi, Wang, Wentao, Xie, Jiacheng, Zhu, Lijing, Chen, Gaofei, Li, Zhengji, Wang, Tianyang, and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Drug target binding affinity (DTA) is a key criterion for drug screening. Existing experimental methods are time-consuming and rely on limited structural and domain information. While learning-based methods can model sequence and structural information, they struggle to integrate contextual data and often lack comprehensive modeling of drug-target interactions. In this study, we propose a novel DTA prediction method, termed HGTDP-DTA, which utilizes dynamic prompts within a hybrid Graph-Transformer framework. Our method generates context-specific prompts for each drug-target pair, enhancing the model's ability to capture unique interactions. The introduction of prompt tuning further optimizes the prediction process by filtering out irrelevant noise and emphasizing task-relevant information, dynamically adjusting the input features of the molecular graph. The proposed hybrid Graph-Transformer architecture combines structural information from Graph Convolutional Networks (GCNs) with sequence information captured by Transformers, facilitating the interaction between global and local information. Additionally, we adopted the multi-view feature fusion method to project molecular graph views and affinity subgraph views into a common feature space, effectively combining structural and contextual information. Experiments on two widely used public datasets, Davis and KIBA, show that HGTDP-DTA outperforms state-of-the-art DTA prediction methods in both prediction performance and generalization ability.
- Published
- 2024
36. Vox-UDA: Voxel-wise Unsupervised Domain Adaptation for Cryo-Electron Subtomogram Segmentation with Denoised Pseudo Labeling
- Author
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Li, Haoran, Li, Xingjian, Shi, Jiahua, Chen, Huaming, Du, Bo, Kihara, Daisuke, Barthelemy, Johan, Shen, Jun, and Xu, Min
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
Cryo-Electron Tomography (cryo-ET) is a 3D imaging technology facilitating the study of macromolecular structures at near-atomic resolution. Recent volumetric segmentation approaches on cryo-ET images have drawn widespread interest in biological sector. However, existing methods heavily rely on manually labeled data, which requires highly professional skills, thereby hindering the adoption of fully-supervised approaches for cryo-ET images. Some unsupervised domain adaptation (UDA) approaches have been designed to enhance the segmentation network performance using unlabeled data. However, applying these methods directly to cryo-ET images segmentation tasks remains challenging due to two main issues: 1) the source data, usually obtained through simulation, contain a certain level of noise, while the target data, directly collected from raw-data from real-world scenario, have unpredictable noise levels. 2) the source data used for training typically consists of known macromoleculars, while the target domain data are often unknown, causing the model's segmenter to be biased towards these known macromolecules, leading to a domain shift problem. To address these challenges, in this work, we introduce the first voxel-wise unsupervised domain adaptation approach, termed Vox-UDA, specifically for cryo-ET subtomogram segmentation. Vox-UDA incorporates a noise generation module to simulate target-like noises in the source dataset for cross-noise level adaptation. Additionally, we propose a denoised pseudo-labeling strategy based on improved Bilateral Filter to alleviate the domain shift problem. Experimental results on both simulated and real cryo-ET subtomogram datasets demonstrate the superiority of our proposed approach compared to state-of-the-art UDA methods., Comment: 11 pages
- Published
- 2024
37. Multiscale Tests for Point Processes and Longitudinal Networks
- Author
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Jiang, Youmeng and Xu, Min
- Subjects
Statistics - Methodology ,Mathematics - Statistics Theory ,62Mxx - Abstract
We propose a new testing framework applicable to both the two-sample problem on point processes and the community detection problem on rectangular arrays of point processes, which we refer to as longitudinal networks; the latter problem is useful in situations where we observe interactions among a group of individuals over time. Our framework is based on a multiscale discretization scheme that consider not just the global null but also a collection of nulls local to small regions in the domain; in the two-sample problem, the local rejections tell us where the intensity functions differ and in the longitudinal network problem, the local rejections tell us when the community structure is most salient. We provide theoretical analysis for the two-sample problem and show that our method has minimax optimal power under a Holder continuity condition. We provide extensive simulation and real data analysis demonstrating the practicality of our proposed method., Comment: 59 pages, 9 figures
- Published
- 2024
38. Distilling Aggregated Knowledge for Weakly-Supervised Video Anomaly Detection
- Author
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Dalvi, Jash, Dabouei, Ali, Dhanuka, Gunjan, and Xu, Min
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
Video anomaly detection aims to develop automated models capable of identifying abnormal events in surveillance videos. The benchmark setup for this task is extremely challenging due to: i) the limited size of the training sets, ii) weak supervision provided in terms of video-level labels, and iii) intrinsic class imbalance induced by the scarcity of abnormal events. In this work, we show that distilling knowledge from aggregated representations of multiple backbones into a relatively simple model achieves state-of-the-art performance. In particular, we develop a bi-level distillation approach along with a novel disentangled cross-attention-based feature aggregation network. Our proposed approach, DAKD (Distilling Aggregated Knowledge with Disentangled Attention), demonstrates superior performance compared to existing methods across multiple benchmark datasets. Notably, we achieve significant improvements of 1.36%, 0.78%, and 7.02% on the UCF-Crime, ShanghaiTech, and XD-Violence datasets, respectively.
- Published
- 2024
39. Suppression of Cavity Time-Delay Signature Using Noise-Phase-Modulated Feedback
- Author
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Hong Han, Xu Min Cheng, Zhi Wei Jia, and K. Alan Shore
- Subjects
Chaos ,noise phase modulation ,time-delay signature ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
We propose reconfiguration of the conventional feedback scheme to suppress the external-cavity time-delay signature (TDS) by adding noise phase modulation in the feedback of semiconductor laser. Noise-phase-modulated feedback introduces broad band noise frequencies into the feedback light and enables the suppression of the TDS. In this work, by means of simulations, the effect on TDS suppression of phase modulation (PM) index is explored. In addition, the influence of noise bandwidth variation is investigated. Using the auto-correlation function to quantity the TDS, we find that, for a large range of operating parameters, the TDS is significantly suppressed to the noise level and even submerged into the base noise. It is shown that suppression TDS is achievable over a wide operating parameter provided the noise generator bandwidth is of order 10 GHz and the PM index is greater than about 3. The proposed configuration will have widespread applications in contexts where suppression of the TDS is required.
- Published
- 2020
- Full Text
- View/download PDF
40. Key technology analysis and research progress of UAV intelligent plant protection
- Author
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Xu Min, Zhang Ruirui, Chen Liping, Tang Qing, Xu Gang
- Subjects
uav ,plant protection ,intelligence ,sensing ,spraying ,Agriculture (General) ,S1-972 ,Technology (General) ,T1-995 - Abstract
UAV plant protection operation faces very complicated environmental conditions. On one hand, its ultra low altitude operations are vulnerable to ground structures and basic hydropower facilities; on the other hand, the effectiveness of plant protection operation is strong, and it is necessary to spray the pesticides to the specific parts of crops at the prescribed time so as to ensure good pesticide application effect. At present, UAV plant protection technology mainly refers to the existing mature technology and flight platform in general aviation field to basically "fly and spray". However, the lack of penetrating research and theoretical guidance on environmental perception in farmland operation, the movement mechanism of droplets under the rotor airflow, and the penetrability of the droplet to different crops canopy lead to low penetration rate of the UAV plant protection operation, easy drifting, frequent accidents, large damage probability and low comprehensive operational efficiency. Benefiting from the breakthroughs in artificial intelligence, parallel computing technology and intelligent hardware, the UAV plant protection technology is developing in the direction of intellectualization, systematization and precision. The real-time perception of the environment under non established conditions, intelligent job decision method based on intelligent recognition of crop diseases and pests, the control of the toward-target pesticide spraying control based on the variable of wind field droplet deposition model and the data based job evaluation system have gradually become the key technology of the UAV intelligent plant protection. The manuscript analyzed and summarized the research status and technical achievements in the field of UAV intelligent plant protection from the field information perception, the modeling and optimization control of accurate pesticide application, the evaluation and monitoring of the operation effect. Based on the existing research, the research also predicted the development trend of the key technologies of intelligent UAV plant protection in the future. The clustering method of hyper-spectral image acquisition and computational intelligence based deep learning recognition will become the key technology for real-time and efficient acquisition of crop target information in plant protection work, which greatly improves the accuracy of remote sensing information inversion recognition; machine vision and multi machine cooperative sensing technology can acquire dynamic information of field operation at multiple levels and time; the high precision droplet spectrum control technology independently controlled by nozzle design and the precision variable spraying control technology based on the wind field model can further improve the droplet deposition effect and reduce the liquid drifting; the breakthrough of high accuracy mesh solution technology will change the prediction mode of droplet drift from artificial experience judgment to computer simulation and numerical deduction; the job path planning technology will greatly improve the efficiency of multi machine and multi area operation and reduce the distance of invalid operation; the job quality evaluation based on the real-time data of the sensor and the operation supervision system of large data technology will replace people to effectively control the process of the UAV plant protection operation, achieve data and transparency of plant protection, and ensure the process is observable and controllable.
- Published
- 2019
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- View/download PDF
41. The role of shear flow collapse and enhanced turbulence spreading in edge cooling approaching the density limit
- Author
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Long, Ting, Diamond, PH, Ke, Rui, Chen, Zhipeng, Xu, Xin, Tian, Wenjing, Hong, Rongjie, Cao, Mingyun, Liu, Yanmin, Xu, Min, Wang, Lu, Yang, Zhoujun, Yuan, Jinbang, Zhou, Yongkang, Yan, Qinghao, Yang, Qinghu, Shen, Chengshuo, Nie, Lin, Wang, Zhanhui, Hao, Guangzhou, Wang, Nengchao, Chen, Zhongyong, Li, Jiquan, Chen, Wei, and Zhong, Wulyu
- Subjects
Nuclear and Plasma Physics ,Physical Sciences ,tokamak ,density limit ,edge cooling ,turbulence spreading ,shear flow ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Fluids & Plasmas ,Nuclear and plasma physics - Abstract
Experimental studies of the dynamics of shear flow and turbulence spreading at the edge of tokamak plasmas are reported. Scans of line-averaged density and plasma current are carried out while approaching the Greenwald density limit on the J-TEXT tokamak. In all scans, when the Greenwald fraction f G = n ¯ / n G = n ¯ / ( I p / π a 2 ) increases, a common feature of enhanced turbulence spreading and edge cooling is found. The result suggests that turbulence spreading is a good indicator of edge cooling, indeed better than turbulent particle transport is. The normalized turbulence spreading power increases significantly when the normalized E × B shearing rate decreases. This indicates that turbulence spreading becomes prominent when the shearing rate is weaker than the turbulence scattering rate. The asymmetry between positive/negative (blobs/holes) spreading events, turbulence spreading power and shear flow are discussed. These results elucidate the important effects of interaction between shear flow and turbulence spreading on plasma edge cooling.
- Published
- 2024
42. DualContrast: Unsupervised Disentangling of Content and Transformations with Implicit Parameterization
- Author
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Uddin, Mostofa Rafid and Xu, Min
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
Unsupervised disentanglement of content and transformation has recently drawn much research, given their efficacy in solving downstream unsupervised tasks like clustering, alignment, and shape analysis. This problem is particularly important for analyzing shape-focused real-world scientific image datasets, given their significant relevance to downstream tasks. The existing works address the problem by explicitly parameterizing the transformation factors, significantly reducing their expressiveness. Moreover, they are not applicable in cases where transformations can not be readily parametrized. An alternative to such explicit approaches is self-supervised methods with data augmentation, which implicitly disentangles transformations and content. We demonstrate that the existing self-supervised methods with data augmentation result in the poor disentanglement of content and transformations in real-world scenarios. Therefore, we developed a novel self-supervised method, DualContrast, specifically for unsupervised disentanglement of content and transformations in shape-focused image datasets. Our extensive experiments showcase the superiority of DualContrast over existing self-supervised and explicit parameterization approaches. We leveraged DualContrast to disentangle protein identities and protein conformations in cellular 3D protein images. Moreover, we also disentangled transformations in MNIST, viewpoint in the Linemod Object dataset, and human movement deformation in the Starmen dataset as transformations using DualContrast.
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- 2024
43. Synergistic Global-space Camera and Human Reconstruction from Videos
- Author
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Zhao, Yizhou, Wang, Tuanfeng Y., Raj, Bhiksha, Xu, Min, Yang, Jimei, and Huang, Chun-Hao Paul
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence - Abstract
Remarkable strides have been made in reconstructing static scenes or human bodies from monocular videos. Yet, the two problems have largely been approached independently, without much synergy. Most visual SLAM methods can only reconstruct camera trajectories and scene structures up to scale, while most HMR methods reconstruct human meshes in metric scale but fall short in reasoning with cameras and scenes. This work introduces Synergistic Camera and Human Reconstruction (SynCHMR) to marry the best of both worlds. Specifically, we design Human-aware Metric SLAM to reconstruct metric-scale camera poses and scene point clouds using camera-frame HMR as a strong prior, addressing depth, scale, and dynamic ambiguities. Conditioning on the dense scene recovered, we further learn a Scene-aware SMPL Denoiser to enhance world-frame HMR by incorporating spatio-temporal coherency and dynamic scene constraints. Together, they lead to consistent reconstructions of camera trajectories, human meshes, and dense scene point clouds in a common world frame. Project page: https://paulchhuang.github.io/synchmr, Comment: CVPR 2024
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- 2024
44. MediCLIP: Adapting CLIP for Few-shot Medical Image Anomaly Detection
- Author
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Zhang, Ximiao, Xu, Min, Qiu, Dehui, Yan, Ruixin, Lang, Ning, and Zhou, Xiuzhuang
- Subjects
Computer Science - Computer Vision and Pattern Recognition - Abstract
In the field of medical decision-making, precise anomaly detection in medical imaging plays a pivotal role in aiding clinicians. However, previous work is reliant on large-scale datasets for training anomaly detection models, which increases the development cost. This paper first focuses on the task of medical image anomaly detection in the few-shot setting, which is critically significant for the medical field where data collection and annotation are both very expensive. We propose an innovative approach, MediCLIP, which adapts the CLIP model to few-shot medical image anomaly detection through self-supervised fine-tuning. Although CLIP, as a vision-language model, demonstrates outstanding zero-/fewshot performance on various downstream tasks, it still falls short in the anomaly detection of medical images. To address this, we design a series of medical image anomaly synthesis tasks to simulate common disease patterns in medical imaging, transferring the powerful generalization capabilities of CLIP to the task of medical image anomaly detection. When only few-shot normal medical images are provided, MediCLIP achieves state-of-the-art performance in anomaly detection and location compared to other methods. Extensive experiments on three distinct medical anomaly detection tasks have demonstrated the superiority of our approach. The code is available at https://github.com/cnulab/MediCLIP., Comment: 12 pages, 3 figures, 5 tables, early accepted at MICCAI 2024
- Published
- 2024
45. Conditional Local Feature Encoding for Graph Neural Networks
- Author
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Wang, Yongze, Zhang, Haimin, Wu, Qiang, and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Social and Information Networks - Abstract
Graph neural networks (GNNs) have shown great success in learning from graph-based data. The key mechanism of current GNNs is message passing, where a node's feature is updated based on the information passing from its local neighbourhood. A limitation of this mechanism is that node features become increasingly dominated by the information aggregated from the neighbourhood as we use more rounds of message passing. Consequently, as the GNN layers become deeper, adjacent node features tends to be similar, making it more difficult for GNNs to distinguish adjacent nodes, thereby, limiting the performance of GNNs. In this paper, we propose conditional local feature encoding (CLFE) to help prevent the problem of node features being dominated by the information from local neighbourhood. The idea of our method is to extract the node hidden state embedding from message passing process and concatenate it with the nodes feature from previous stage, then we utilise linear transformation to form a CLFE based on the concatenated vector. The CLFE will form the layer output to better preserve node-specific information, thus help to improve the performance of GNN models. To verify the feasibility of our method, we conducted extensive experiments on seven benchmark datasets for four graph domain tasks: super-pixel graph classification, node classification, link prediction, and graph regression. The experimental results consistently demonstrate that our method improves model performance across a variety of baseline GNN models for all four tasks., Comment: 11 pages
- Published
- 2024
46. ERAGent: Enhancing Retrieval-Augmented Language Models with Improved Accuracy, Efficiency, and Personalization
- Author
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Shi, Yunxiao, Zi, Xing, Shi, Zijing, Zhang, Haimin, Wu, Qiang, and Xu, Min
- Subjects
Computer Science - Computation and Language - Abstract
Retrieval-augmented generation (RAG) for language models significantly improves language understanding systems. The basic retrieval-then-read pipeline of response generation has evolved into a more extended process due to the integration of various components, sometimes even forming loop structures. Despite its advancements in improving response accuracy, challenges like poor retrieval quality for complex questions that require the search of multifaceted semantic information, inefficiencies in knowledge re-retrieval during long-term serving, and lack of personalized responses persist. Motivated by transcending these limitations, we introduce ERAGent, a cutting-edge framework that embodies an advancement in the RAG area. Our contribution is the introduction of the synergistically operated module: Enhanced Question Rewriter and Knowledge Filter, for better retrieval quality. Retrieval Trigger is incorporated to curtail extraneous external knowledge retrieval without sacrificing response quality. ERAGent also personalizes responses by incorporating a learned user profile. The efficiency and personalization characteristics of ERAGent are supported by the Experiential Learner module which makes the AI assistant being capable of expanding its knowledge and modeling user profile incrementally. Rigorous evaluations across six datasets and three question-answering tasks prove ERAGent's superior accuracy, efficiency, and personalization, emphasizing its potential to advance the RAG field and its applicability in practical systems., Comment: Draft Paper
- Published
- 2024
47. Physical Vapor Deposition of High Mobility P-type Tellurium and its Applications for Gate-tunable van der Waals PN Photodiodes
- Author
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Huang, Tianyi, Lin, Sen, Zou, Jingyi, Wang, Zexiao, Zhong, Yibai, Li, Jingwei, Wang, Ruixuan, Wang, Han, Li, Qing, Xu, Min, Shen, Sheng, and Zhang, Xu
- Subjects
Physics - Applied Physics - Abstract
Recently tellurium (Te) has attracted resurgent interests due to its p-type characteristics and outstanding ambient environmental stability. Here we present a substrate engineering based physical vapor deposition method to synthesize high-quality Te nanoflakes and achieved a field-effect hole mobility of 1500 cm2/Vs, which is, to the best of our knowledge, the highest among the existing synthesized van der Waals p-type semiconductors. The high mobility Te enables the fabrication of Te/MoS2 pn diodes with highly gate-tunable electronic and optoelectronic characteristics. The Te/MoS2 heterostructure can be used as a visible range photodetector with a current responsivity up to 630 A/W, which is about one order of magnitude higher than the one achieved using p-type Si-MoS2 PN photodiodes. The photo response of the Te/MoS2 heterojunction also exhibits strong gate tunability due to their ultrathin thickness and unique band structures. The successful synthesis of high mobility Te and the enabled Te/MoS2 photodiodes show promise for the development of highly tunable and ultrathin photodetectors.
- Published
- 2024
48. Neighbour-level Message Interaction Encoding for Improved Representation Learning on Graphs
- Author
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Zhang, Haimin and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Message passing has become the dominant framework in graph representation learning. The essential idea of the message-passing framework is to update node embeddings based on the information aggregated from local neighbours. However, most existing aggregation methods have not encoded neighbour-level message interactions into the aggregated message, resulting in an information lost in embedding generation. And this information lost could be accumulated and become more serious as more layers are added to the graph network model. To address this issue, we propose a neighbour-level message interaction information encoding method for improving graph representation learning. For messages that are aggregated at a node, we explicitly generate an encoding between each message and the rest messages using an encoding function. Then we aggregate these learned encodings and take the sum of the aggregated encoding and the aggregated message to update the embedding for the node. By this way, neighbour-level message interaction information is integrated into the generated node embeddings. The proposed encoding method is a generic method which can be integrated into message-passing graph convolutional networks. Extensive experiments are conducted on six popular benchmark datasets across four highly-demanded tasks. The results show that integrating neighbour-level message interactions achieves improved performance of the base models, advancing the state of the art results for representation learning over graphs., Comment: 10 pages
- Published
- 2024
49. RandAlign: A Parameter-Free Method for Regularizing Graph Convolutional Networks
- Author
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Zhang, Haimin and Xu, Min
- Subjects
Computer Science - Machine Learning ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Studies continually find that message-passing graph convolutional networks suffer from the over-smoothing issue. Basically, the issue of over-smoothing refers to the phenomenon that the learned embeddings for all nodes can become very similar to one another and therefore are uninformative after repeatedly applying message passing iterations. Intuitively, we can expect the generated embeddings become smooth asymptotically layerwisely, that is each layer of graph convolution generates a smoothed version of embeddings as compared to that generated by the previous layer. Based on this intuition, we propose RandAlign, a stochastic regularization method for graph convolutional networks. The idea of RandAlign is to randomly align the learned embedding for each node with that of the previous layer using randomly interpolation in each graph convolution layer. Through alignment, the smoothness of the generated embeddings is explicitly reduced. To better maintain the benefit yielded by the graph convolution, in the alignment step we introduce to first scale the embedding of the previous layer to the same norm as the generated embedding and then perform random interpolation for aligning the generated embedding. RandAlign is a parameter-free method and can be directly applied without introducing additional trainable weights or hyper-parameters. We experimentally evaluate RandAlign on different graph domain tasks on seven benchmark datasets. The experimental results show that RandAlign is a general method that improves the generalization performance of various graph convolutional network models and also improves the numerical stability of optimization, advancing the state of the art performance for graph representation learning., Comment: 10 pages
- Published
- 2024
50. CryoMAE: Few-Shot Cryo-EM Particle Picking with Masked Autoencoders
- Author
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Xu, Chentianye, Zhan, Xueying, and Xu, Min
- Subjects
Quantitative Biology - Biomolecules ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Cryo-electron microscopy (cryo-EM) emerges as a pivotal technology for determining the architecture of cells, viruses, and protein assemblies at near-atomic resolution. Traditional particle picking, a key step in cryo-EM, struggles with manual effort and automated methods' sensitivity to low signal-to-noise ratio (SNR) and varied particle orientations. Furthermore, existing neural network (NN)-based approaches often require extensive labeled datasets, limiting their practicality. To overcome these obstacles, we introduce cryoMAE, a novel approach based on few-shot learning that harnesses the capabilities of Masked Autoencoders (MAE) to enable efficient selection of single particles in cryo-EM images. Contrary to conventional NN-based techniques, cryoMAE requires only a minimal set of positive particle images for training yet demonstrates high performance in particle detection. Furthermore, the implementation of a self-cross similarity loss ensures distinct features for particle and background regions, thereby enhancing the discrimination capability of cryoMAE. Experiments on large-scale cryo-EM datasets show that cryoMAE outperforms existing state-of-the-art (SOTA) methods, improving 3D reconstruction resolution by up to 22.4%.
- Published
- 2024
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