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The previous advancements in pathology image understanding primarily involved developing models tailored to specific tasks. Recent studies has demonstrated that the large vision-language model can enhance the performance of various downstream tasks in medical image understanding. In this study, we developed a domain-specific large language-vision assistant (PA-LLaVA) for pathology image understanding. Specifically, (1) we first construct a human pathology image-text dataset by cleaning the public medical image-text data for domain-specific alignment; (2) Using the proposed image-text data, we first train a pathology language-image pretraining (PLIP) model as the specialized visual encoder for pathology image, and then we developed scale-invariant connector to avoid the information loss caused by image scaling; (3) We adopt two-stage learning to train PA-LLaVA, first stage for domain alignment, and second stage for end to end visual question \& answering (VQA) task. In experiments, we evaluate our PA-LLaVA on both supervised and zero-shot VQA datasets, our model achieved the best overall performance among multimodal models of similar scale. The ablation experiments also confirmed the effectiveness of our design. We posit that our PA-LLaVA model and the datasets presented in this work can promote research in field of computational pathology. All codes are available at: https://github.com/ddw2AIGROUP2CQUPT/PA-LLaVA}{https://github.com/ddw2AIGROUP2CQUPT/PA-LLaVA, Comment: 8 pages, 4 figs

Interactive segmentation algorithms based on click points have garnered significant attention from researchers in recent years. However, existing studies typically use sparse click maps as model inputs to segment specific target objects, which primarily affect local regions and have limited abilities to focus on the whole target object, leading to increased times of clicks. In addition, most existing algorithms can not balance well between high performance and efficiency. To address this issue, we propose a click attention algorithm that expands the influence range of positive clicks based on the similarity between positively-clicked regions and the whole input. We also propose a discriminative affinity loss to reduce the attention coupling between positive and negative click regions to avoid an accuracy decrease caused by mutual interference between positive and negative clicks. Extensive experiments demonstrate that our approach is superior to existing methods and achieves cutting-edge performance in fewer parameters. An interactive demo and all reproducible codes will be released at https://github.com/hahamyt/ClickAttention.

Just as humans can become disoriented in featureless deserts or thick fogs, not all environments are conducive to the Localization Accuracy and Stability (LAS) of autonomous robots. This paper introduces an efficient framework designed to enhance LiDAR-based LAS through strategic trajectory generation, known as Perception-aware Planning. Unlike vision-based frameworks, the LiDAR-based requires different considerations due to unique sensor attributes. Our approach focuses on two main aspects: firstly, assessing the impact of LiDAR observations on LAS. We introduce a perturbation-induced metric to provide a comprehensive and reliable evaluation of LiDAR observations. Secondly, we aim to improve motion planning efficiency. By creating a Static Observation Loss Map (SOLM) as an intermediary, we logically separate the time-intensive evaluation and motion planning phases, significantly boosting the planning process. In the experimental section, we demonstrate the effectiveness of the proposed metrics across various scenes and the feature of trajectories guided by different metrics. Ultimately, our framework is tested in a real-world scenario, enabling the robot to actively choose topologies and orientations preferable for localization. The source code is accessible at https://github.com/ZJU-FAST-Lab/LF-3PM.

Dynamic jumping on high platforms and over gaps differentiates legged robots from wheeled counterparts. Compared to walking on rough terrains, dynamic locomotion on abrupt surfaces requires fusing proprioceptive and exteroceptive perception for explosive movements. In this paper, we propose SF-TIM (Simple Framework combining Terrain Imagination and Measurement), a single-policy method that enhances quadrupedal robot jumping agility, while preserving their fundamental blind walking capabilities. In addition, we introduce a terrain-guided reward design specifically to assist quadrupedal robots in high jumping, improving their performance in this task. To narrow the simulation-to-reality gap in quadrupedal robot learning, we introduce a stable and high-speed elevation map generation framework, enabling zero-shot simulation-to-reality transfer of locomotion ability. Our algorithm has been deployed and validated on both the small-/large-size quadrupedal robots, demonstrating its effectiveness in real-world applications: the robot has successfully traversed various high platforms and gaps, showing the robustness of our proposed approach. A demo video has been made available at https://flysoaryun.github.io/SF-TIM., Comment: A demo video has been made available at https://flysoaryun.github.io/SF-TIM

Rapid progress in AI technologies has generated considerable interest in their potential to address challenges in every field and education is no exception. Improving learning outcomes and providing relevant education to all have been dominant themes universally, both in the developed and developing world. And they have taken on greater significance in the current era of technology driven personalization.

In recent times, an increasing number of researchers have been devoted to utilizing deep neural networks for end-to-end flight navigation. This approach has gained traction due to its ability to bridge the gap between perception and planning that exists in traditional methods, thereby eliminating delays between modules. However, the practice of replacing original modules with neural networks in a black-box manner diminishes the overall system's robustness and stability. It lacks principled explanations and often fails to consistently generate high-quality motion trajectories. Furthermore, such methods often struggle to rigorously account for the robot's kinematic constraints, resulting in the generation of trajectories that cannot be executed satisfactorily. In this work, we combine the advantages of traditional methods and neural networks by proposing an optimization-embedded neural network. This network can learn high-quality trajectories directly from visual inputs without the need of mapping, while ensuring dynamic feasibility. Here, the deep neural network is employed to directly extract environment safety regions from depth images. Subsequently, we employ a model-based approach to represent these regions as safety constraints in trajectory optimization. Leveraging the availability of highly efficient optimization algorithms, our method robustly converges to feasible and optimal solutions that satisfy various user-defined constraints. Moreover, we differentiate the optimization process, allowing it to be trained as a layer within the neural network. This approach facilitates the direct interaction between perception and planning, enabling the network to focus more on the spatial regions where optimal solutions exist. As a result, it further enhances the quality and stability of the generated trajectories., Comment: Some statements in the introduction may be controversial

Click-point-based interactive segmentation has received widespread attention due to its efficiency. However, it's hard for existing algorithms to obtain precise and robust responses after multiple clicks. In this case, the segmentation results tend to have little change or are even worse than before. To improve the robustness of the response, we propose a structured click intent model based on graph neural networks, which adaptively obtains graph nodes via the global similarity of user-clicked Transformer tokens. Then the graph nodes will be aggregated to obtain structured interaction features. Finally, the dual cross-attention will be used to inject structured interaction features into vision Transformer features, thereby enhancing the control of clicks over segmentation results. Extensive experiments demonstrated the proposed algorithm can serve as a general structure in improving Transformer-based interactive segmenta?tion performance. The code and data will be released at https://github.com/hahamyt/scc., Comment: 10 pages, 6 figures, submitted to NeurIPS 2024

In group sequential designs, where several data looks are conducted for early stopping, we generally assume the vector of test statistics from the sequential analyses follows (at least approximately or asymptotially) a multivariate normal distribution. However, it is well-known that test statistics for which an asymptotic distribution is derived may suffer from poor small sample approximation. This might become even worse with an increasing number of data looks. The aim of this paper is to improve the small sample behaviour of group sequential designs while maintaining the same asymptotic properties as classical group sequential designs. This improvement is achieved through the application of a modified permutation test. In particular, this paper shows that the permutation distribution approximates the distribution of the test statistics not only under the null hypothesis but also under the alternative hypothesis, resulting in an asymptotically valid permutation test. An extensive simulation study shows that the proposed permutation test better controls the Type I error rate than its competitors in the case of small sample sizes., Comment: 30 pages, 14 figures

Interactive segmentation has gained significant attention for its application in human-computer interaction and data annotation. To address the target scale variation issue in interactive segmentation, a novel multi-scale token adaptation algorithm is proposed. By performing top-k operations across multi-scale tokens, the computational complexity is greatly simplified while ensuring performance. To enhance the robustness of multi-scale token selection, we also propose a token learning algorithm based on contrastive loss. This algorithm can effectively improve the performance of multi-scale token adaptation. Extensive benchmarking shows that the algorithm achieves state-of-the-art (SOTA) performance, compared to current methods. An interactive demo and all reproducible codes will be released at https://github.com/hahamyt/mst., Comment: 11 pages, 10 figures

We investigate the persistent orientation of asymmetric-top molecules induced by time-delayed THz pulses that are either collinearly or cross polarized. Our theoretical and numerical results demonstrate that the orthogonal configuration outperforms the collinear one, and a significant degree of persistent orientation - approximately 10% at 5 K and nearly 3% at room temperature - may be achieved through parameter optimization. The dependence of the persistent orientation factor on temperature and field parameters is studied in detail. The proposed application of two orthogonally polarized THz pulses is both practical and efficient. Its applicability under standard laboratory conditions lays a solid foundation for future experimental realization of THz-induced persistent molecular orientation., Comment: 11 pages, 6 figures

Wide binaries play a crucial role in analyzing the birth environment of stars and the dynamical evolution of clusters. When wide binaries are located at greater distances, their companions may overlap in the observed images, becoming indistinguishable and resulting in unresolved wide binaries, which are difficult to detect using traditional methods. Utilizing deep learning, we present a method to identify unresolved wide binaries by analyzing the point-spread function (PSF) morphology of telescopes. Our trained model demonstrates exceptional performance in differentiating between single stars and unresolved binaries with separations ranging from 0.1 to 2 physical pixels, where the PSF FWHM is ~2 pixels, achieving an accuracy of 97.2% for simulated data from the Chinese Space Station Telescope. We subsequently tested our method on photometric data of NGC 6121 observed by the Hubble Space Telescope. The trained model attained an accuracy of 96.5% and identified 18 wide binary candidates with separations between 7 and 140 au. The majority of these wide binary candidates are situated outside the core radius of NGC 6121, suggesting that they are likely first-generation stars, which is in general agreement with the results of Monte Carlo simulations. Our PSF-based method shows great promise in detecting unresolved wide binaries and is well suited for observations from space-based telescopes with stable PSF. In the future, we aim to apply our PSF-based method to next-generation surveys such as the China Space Station Optical Survey, where a larger-field-of-view telescope will be capable of identifying a greater number of such wide binaries., Comment: 17 pages, 12 figures. Accepted for publication in ApJS

Autonomous navigation of ground robots on uneven terrain is being considered in more and more tasks. However, uneven terrain will bring two problems to motion planning: how to assess the traversability of the terrain and how to cope with the dynamics model of the robot associated with the terrain. The trajectories generated by existing methods are often too conservative or cannot be tracked well by the controller since the second problem is not well solved. In this paper, we propose terrain pose mapping to describe the impact of terrain on the robot. With this mapping, we can obtain the SE(3) state of the robot on uneven terrain for a given state in SE(2). Then, based on it, we present a trajectory optimization framework for car-like robots on uneven terrain that can consider both of the above problems. The trajectories generated by our method conform to the dynamics model of the system without being overly conservative and yet able to be tracked well by the controller. We perform simulations and real-world experiments to validate the efficiency and trajectory quality of our algorithm.

With the development of robotics, ground robots are no longer limited to planar motion. Passive height variation due to complex terrain and active height control provided by special structures on robots require a more general navigation planning framework beyond 2D. Existing methods rarely considers both simultaneously, limiting the capabilities and applications of ground robots. In this paper, we proposed an optimization-based planning framework for ground robots considering both active and passive height changes on the z-axis. The proposed planner first constructs a penalty field for chassis motion constraints defined in R3 such that the optimal solution space of the trajectory is continuous, resulting in a high-quality smooth chassis trajectory. Also, by constructing custom constraints in the z-axis direction, it is possible to plan trajectories for different types of ground robots which have z-axis degree of freedom. We performed simulations and realworld experiments to verify the efficiency and trajectory quality of our algorithm.

We theoretically consider the phenomenon of field-free long-lasting orientation of symmetric-top molecules ionized by two-color laser pulses. The anisotropic ionization produces a significant long-lasting orientation of the surviving neutral molecules. The degree of orientation increases with both the pulse intensity and, counterintuitively, with the rotational temperature. The orientation may be enhanced even further by using multiple delayed two-color pulses. The long-lasting orientation may be probed by even harmonic generation or by Coulomb-explosion-based methods. The effect may enable the study of relaxation processes in dense molecular gases, and may be useful for molecular guiding and trapping by inhomogeneous fields., Comment: 7 pages, 4 figures

Robot swarm is a hot spot in robotic research community. In this paper, we propose a decentralized framework for car-like robotic swarm which is capable of real-time planning in cluttered environments. In this system, path finding is guided by environmental topology information to avoid frequent topological change, and search-based speed planning is leveraged to escape from infeasible initial value's local minima. Then spatial-temporal optimization is employed to generate a safe, smooth and dynamically feasible trajectory. During optimization, the trajectory is discretized by fixed time steps. Penalty is imposed on the signed distance between agents to realize collision avoidance, and differential flatness cooperated with limitation on front steer angle satisfies the non-holonomic constraints. With trajectories broadcast to the wireless network, agents are able to check and prevent potential collisions. We validate the robustness of our system in simulation and real-world experiments. Code will be released as open-source packages., Comment: Accepted by IROS 2023