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18 results on '"Xu, Jiujin"'

3. Male demography in East Asia:a North-South contrast in human population expansion times

Author

Xue, Yali, Zerjal, Tatiana, Bao, Weidong, Zhu, Suling, Shu, Qunfang, Xu, Jiujin, Du, Ruofu, Fu, Songbin, Li, Pu, Hurles, Matthew E., Yang, Huanming, and Tyler-Smith, Chris

Subjects
Demographic surveys -- Analysis, Population -- Growth, Population -- Analysis, Biological sciences
Abstract

The human population has increased greatly in size in the last 100,000 years, but the initial stimuli to growth, the times when expansion started, and their variation between different parts of the world are poorly understood. We have investigated male demography in East Asia, applying a Bayesian full-likelihood analysis to data from 988 men representing 27 populations from China, Mongolia, Korea, and Japan typed with 45 binary and 16 STR markers from the Y chromosome. According to our analysis, the northern populations examined all started to expand in number between 34 (18-68) and 22 (12-39) thousand years ago (KYA), before the last glacial maximum at 21-18 KYA, while the southern populations all started to expand between 18 (6-47) and 12 (1-45) KYA, but then grew faster. We suggest that the northern populations expanded earlier because they could exploit the abundant megafauna of the 'Mammoth Steppe,' while the southern populations could increase in number only when a warmer and more stable climate led to more plentiful plant resources such as tubers.

Published
2006

4. Recent spread of a Y-chromosomal lineage in northern China and Mongolia

Author

Xue, Yali, Zerjal, Tatiana, Bao, Weidong, Zhu, Suling, Lim, Si-Keun, Shu, Qunfang, Xu, Jiujin, Du, Roufu, Fu, Songbin, Li, Pu, Yang, Huanming, and Tyler-Smith, Chris

Subjects
Human beings -- Genetic aspects, Man -- Genetic aspects, Human chromosome abnormalities -- Research, Biological sciences
Published
2005

5. The genetic legacy of the Mongols. (Report)

Author

Zerjal, Tatiana, Xue, Yali, Bertorelle, Giorgio, Wells, R. Spencer, Bao, Weidong, Zhu, Suling, Qamar, Raheel, Ayub, Qasim, Mohyuddin, Aisha, Fu, Songbin, Li, Pu, Yuldasheva, Nadira, Ruzibakiev, Ruslan, Xu, Jiujin, Shu, Qunfang, Du, Ruofu, Yang, Huanming, Hurles, Matthew E., Robinson, Elizabeth, Gerelsaikhan, Tudevdagva, Dashnyam, Bumbein, Mehdi, S. Qasim, and Tyler-Smith, Chris

Subjects
Mongols -- Genetic aspects, Natural selection -- Case studies, Natural selection -- Genetic aspects, Genetic research, Biological sciences
Published
2003

6. A Human Genome Diversity Cell Line Panel

Author

Cann, Howard M., de Toma, Claudia, Cazes, Lucien, Legrand, Marie-Fernande, Morel, Valerie, Piouffre, Laurence, Bodmer, Julia, Bodmer, Walter F., Bonne-Tamir, Batsheva, Cambon-Thomsen, Anne, Chen, Zhu, Chu, Jiayou, Carcassi, Carlo, Contu, Licinio, Du, Ruofu, Excoffier, Laurent, Ferrara, G. B., Friedlaender, Jonathan S., Groot, Helena, Gurwitz, David, Jenkins, Trefor, Herrera, Rene J., Huang, Xiaoyi, Kidd, Judith, Kidd, Kenneth K., Langaney, Andre, Lin, Alice A., Mehdi, S. Qasim, Parham, Peter, Piazza, Alberto, Pistillo, Maria Pia, Qian, Yaping, Shu, Qunfang, Xu, Jiujin, Zhu, S., Weber, James L., Greely, Henry T., Feldman, Marcus W., Thomas, Gilles, Dausset, Jean, and Cavalli-Sforza, L. Luca

Published
2002

7. Distribution of YAP in 10 populations of China

Author

Bao Weidong, Zhu Suling, Du Ruofu, Xu Jiujin, and Xu Liping

Subjects
Genetics, Multidisciplinary, Polymorphism (computer science), business.industry, Alu element, Distribution (economics), Biology, China, Y chromosome, business
Abstract

The Y-chromosome Alu polymorphism was studied in 10 populations in China. The Alu insertion is present in 54/571 individuals (9%). Among 10 populations, the frequency of YAP element is quite high (49%) in the Tibetans and at moderate or low levels (15%-4%) in the Yi, Hui and Uygur. The Alu insertion is absent in the Han in Guangdong and Shaanxi, and in the Manchu and Zhuang, while a single Tujia individual and a single Yao individual are found to have the Alu insertion.

Published
1998
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8. The DNA methylome of human peripheral blood mononuclear cells

Author

Li, Yingrui, Zhu, Jingde, Tian, Geng, Li, Ning, Li, Qibin, Ye, Mingzhi, Zheng, Hancheng, Yu, Jian, Wu, Honglong, Sun, Jihua, Zhang, Hongyu, Chen, Quan, Luo, Ruibang, Chen, Minfeng, He, Yinghua, Jin, Xin, Zhang, Qinghui, Yu, Chang, Zhou, Guangyu, Sun, Jinfeng, Huang, Yebo, Zheng, Huisong, Cao, Hongzhi, Zhou, Xiaoyu, Guo, Shicheng, Hu, Xueda, Li, Xin, Kristiansen, Karsten, Bolund, Lars, Xu, Jiujin, Wang, Wen, Yang, Huanming, Wang, Jian, Li, Ruiqiang, Beck, Stephan, Wang, Jun, Zhang, Xiuqing, Li, Yingrui, Zhu, Jingde, Tian, Geng, Li, Ning, Li, Qibin, Ye, Mingzhi, Zheng, Hancheng, Yu, Jian, Wu, Honglong, Sun, Jihua, Zhang, Hongyu, Chen, Quan, Luo, Ruibang, Chen, Minfeng, He, Yinghua, Jin, Xin, Zhang, Qinghui, Yu, Chang, Zhou, Guangyu, Sun, Jinfeng, Huang, Yebo, Zheng, Huisong, Cao, Hongzhi, Zhou, Xiaoyu, Guo, Shicheng, Hu, Xueda, Li, Xin, Kristiansen, Karsten, Bolund, Lars, Xu, Jiujin, Wang, Wen, Yang, Huanming, Wang, Jian, Li, Ruiqiang, Beck, Stephan, Wang, Jun, and Zhang, Xiuqing

Abstract

DNA methylation plays an important role in biological processes in human health and disease. Recent technological advances allow unbiased whole-genome DNA methylation (methylome) analysis to be carried out on human cells. Using whole-genome bisulfite sequencing at 24.7-fold coverage (12.3-fold per strand), we report a comprehensive (92.62%) methylome and analysis of the unique sequences in human peripheral blood mononuclear cells (PBMC) from the same Asian individual whose genome was deciphered in the YH project. PBMC constitute an important source for clinical blood tests world-wide. We found that 68.4% of CpG sites and 80% displayed allele-specific expression (ASE). These data demonstrate that ASM is a recurrent phenomenon and is highly correlated with ASE in human PBMCs. Together with recently reported similar studies, our study provides a comprehensive resource for future epigenomic research and confirms new sequencing technology as a paradigm for large-scale epigenomics studies.

Published
2010

9. The DNA Methylome of Human Peripheral Blood Mononuclear Cells

Author

Li, Yingrui, primary, Zhu, Jingde, additional, Tian, Geng, additional, Li, Ning, additional, Li, Qibin, additional, Ye, Mingzhi, additional, Zheng, Hancheng, additional, Yu, Jian, additional, Wu, Honglong, additional, Sun, Jihua, additional, Zhang, Hongyu, additional, Chen, Quan, additional, Luo, Ruibang, additional, Chen, Minfeng, additional, He, Yinghua, additional, Jin, Xin, additional, Zhang, Qinghui, additional, Yu, Chang, additional, Zhou, Guangyu, additional, Sun, Jinfeng, additional, Huang, Yebo, additional, Zheng, Huisong, additional, Cao, Hongzhi, additional, Zhou, Xiaoyu, additional, Guo, Shicheng, additional, Hu, Xueda, additional, Li, Xin, additional, Kristiansen, Karsten, additional, Bolund, Lars, additional, Xu, Jiujin, additional, Wang, Wen, additional, Yang, Huanming, additional, Wang, Jian, additional, Li, Ruiqiang, additional, Beck, Stephan, additional, Wang, Jun, additional, and Zhang, Xiuqing, additional

Published
2010
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14. Population Genetic Study in Hainan Island, China. I. Distribution of Blood Genetic Markers.

Author

OMOTO, KEIICHI, primary, HIRAI, MOMOKI, additional, JIN, FENG, additional, MISAWA, SHOGO, additional, WASHIO, KEIKO, additional, TOKUNAGA, KATSUSHI, additional, YAMAZAKI, KENTARO, additional, SAITOU, NARUYA, additional, DU, CHUANSHU, additional, LU, BAO, additional, LUO, ZHIJUNG, additional, ZENG, ZHIMIN, additional, XU, JIUJIN, additional, ZHAO, HONG, additional, ZHANG, ZHI, additional, WEI, XIERONG, additional, NIU, KEYI, additional, HAO, LUPING, additional, and DU, RUOFU, additional

Published
1993
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15. Polymorphisms of Pi, Hp, ADA and AK in Mongolian, Korean and Zhuang populations of China

Author

Cuid Meiying, Xu Jiujin, L. Kriese, Paweł Bogdański, H.-G. Benkmann, H. W. Goedde, Chen Liangzhong, Li Shizhe, and Du Ruofu

Subjects
Genetic Markers, Genetics, China, Aging, Erythrocytes, Korea, Polymorphism, Genetic, Haptoglobins, Adenosine Deaminase, Physiology, Epidemiology, Adenylate Kinase, Public Health, Environmental and Occupational Health, Genetic Variation, Blood Proteins, Biology, Phenotype, Asian People, alpha 1-Antitrypsin, Genetic variation, Ethnicity, Humans, Minority Groups
Abstract

Three minority ethnic groups from China, Mongolian, Koreans, and Zhuangs were studied for the genetic markers AK, ADA, Hp, and Pi. AK was monomorphic in Koreans and Zhuangs. Significant differences were observed in the Hp system between Mongolians and Zhuangs.

Published
1986
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16. Aldehyde Dehydrogenase Isozyme Deficiency and Alcohol Sensitivity in Four Different Chinese Populations

Author

Cui Meiying, Paweł Bogdański, H. W. Goedde, D.P. Agarwal, Wang Yongfa, Benkmann Hg, Yuan Yida, Du Ruofu, L. Kriese, Xu Jiujin, Chen Liangzhong, and Li Shizhe

Subjects
chemistry.chemical_classification, Genetics, China, Ethanol, biology, Alcohol sensitivity, Aldehyde dehydrogenase, Population genetics, Aldehyde Dehydrogenase, Aldehyde Oxidoreductases, Isozyme, Isoenzymes, Enzyme, Asian People, chemistry, Ethnicity, Flushing, otorhinolaryngologic diseases, biology.protein, Humans, Ethanol metabolism, Genetics (clinical)
Abstract

Four different populations of China were studied regarding aldehyde dehydrogenase isozyme variation and incidence of alcohol sensitivity. While Korean and Mongolian minorities in the north showed an isozyme I deficiency with a frequency of about 25 and 30%, 45-50% of Zhuang and Han were deficient, respectively. Adverse reactions after alcohol drinking were mainly reported by those subjects who showed the lack of aldehyde dehydrogenase isozyme I.

Published
1984
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17. Comparative studies on spontaneous and mitomycin-C-induced sister-chromatid exchanges in smokers and non-smokers

Author

Xu Jiujin, Zhou Xianting, and Cui Meiying

Subjects
Genetics, Male, business.industry, Mitomycin, Mitomycin C, Smoking, General Medicine, Middle Aged, respiratory tract diseases, Mitomycins, Andrology, behavior and behavior mechanisms, Medicine, Sister chromatids, Humans, Crossing Over, Genetic, Lymphocytes, business, Sister Chromatid Exchange, Cells, Cultured
Abstract

Both spontaneous and mitomycin-C-induced sister-chromatid exchanges were analyzed in 6 smokers and 6 non-smokers. The average number of spontaneous SCE in smokers' cells was 8.33 +/- 1.08. The frequency in the non-smoking controls was 4.41 +/- 0.72. This difference is highly significant (P less than 0.001). Smokers also had more SCE at all levels of mitomycin C testes. Analysis of variance showed these differences to be highly significant (P less than 0.001).

Published
1982

18. Distribution of YAP in 10 populations of China.

Author

Xu Liping and Xu Jiujin

Subjects
*Y chromosome, *GENETIC polymorphisms, *CHROMOSOME polymorphism, *HUMAN population genetics
Abstract

Presents a study of Y-chromosome Alu polymorphism (YAP) in ten populations in China. Frequency among Tibetans, Yi, Hui and Uygur tribes; Absence of Alu insertion in Han, Manchu and ZHuang populations.

Published
1998
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