1. Early therapeutic interventions of traditional Chinese medicine in COVID-19 patients: A retrospective cohort study
- Author
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Yunfei Lu, Hua Lü, Wei an Yuan, Gui hua Xu, Xuan Chen, Yi bao Zhang, Xing Zhang, Meng Sun, Shi qi Sun, Yi le Zhang, Qi Chen, Yan Xue, Wei Zhang, Zi jian Su, Miao yan Shi, Xiu ming Song, Xiao rong Chen, and Lu jiong Liu
- Subjects
Adult ,Male ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,0211 other engineering and technologies ,Psychological intervention ,Early interventions ,02 engineering and technology ,Traditional Chinese medicine ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,021105 building & construction ,Medicine ,Humans ,In patient ,Original Research Article ,Medicine, Chinese Traditional ,Aged ,Retrospective Studies ,Conversion time of viral nucleic acid ,Pharyngeal swab ,Coronavirus disease 2019 ,business.industry ,SARS-CoV-2 ,Retrospective cohort study ,General Medicine ,Length of Stay ,Middle Aged ,Inflammatory indicators ,030205 complementary & alternative medicine ,COVID-19 Drug Treatment ,Female ,business ,Hospital stay - Abstract
Objective To observe the early interventions of traditional Chinese Medicine (TCM) on the conversion time of nucleic acid in patients with coronavirus disease 2019 (COVID-19), and find possible underlying mechanisms of action. Methods A retrospective cohort study was conducted on 300 confirmed COVID-19 patients who were treated with TCM, at a designated hospital in China. The patients were categorized into three groups: TCM1, TCM2 and TCM3, who respectively received TCM interventions within 7, 8–14, and greater than 15 days of hospitalization. Different indicators such as the conversion time of pharyngeal swab nucleic acid, the conversion time of fecal nucleic acid, length of hospital stay, and inflammatory markers (leukocyte count, and lymphocyte count and percentage) were analyzed to observe the impact of early TCM interventions on these groups. Results The median conversion times of pharyngeal swab nucleic acid in the three groups were 5.5, 7 and 16 d (P
- Published
- 2020