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Your search keyword '"Xing, Xuejian"' showing total 22 results
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22 results on '"Xing, Xuejian"'

7. Calcium-enriched carbon nanoparticles loaded with indocyanine green for near-infrared fluorescence imaging-guided synergistic calcium overload, photothermal therapy, and glutathione-depletion-enhanced photodynamic therapy

Author

Pang, E, primary, Li, Xiangcao, additional, Zhao, Shaojing, additional, Tang, Yuanyu, additional, Xing, Xuejian, additional, Wang, Qin, additional, Yang, Ke, additional, Wang, Benhua, additional, Jin, Shiguang, additional, Song, Xiangzhi, additional, and Lan, Minhuan, additional

Published
2024
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14. Lysosome- and plasma membrane-accumulative and tumor-targetable polythiophene nanoparticles for enhanced sonodynamic therapy

Author

Pang, E, primary, Xing, Xuejian, additional, Zhao, Shaojing, additional, Tan, Qiuxia, additional, Pan, Tangna, additional, Yu, Ting, additional, Gan, Yabing, additional, Wang, Benhua, additional, Tan, Siyi, additional, Zhang, Yi, additional, Yin, Peng, additional, Song, Xiangzhi, additional, and Lan, Minhuan, additional

Published
2023
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18. Self-assembled quercetin-Fe3+nanoparticles for synergetic near-infrared light-triggered low-temperature photothermal/glutathione-activated chemodynamic therapy

Author

Pan, Tangna, Yang, Ke, Li, Jiwei, Pang, E., Zhao, Shaojing, Xing, Xuejian, Tan, Qiuxia, Wang, Qin, Yi, Jianing, and Lan, Minhuan

Abstract

Combining photothermal therapy (PTT) with chemodynamic therapy (CDT) is an efficacious strategy for cancer treatment. However, the hyperthermia-induced heat shock response and low Fenton reaction efficiency limited its clinical application. Here, we present self-assembled querce-tin-Fe3+nanoparticles (Qu-Fe NPs) for synergetic near-infrared (NIR) light-triggered low-temperature PTT (LTPTT) and glutathione (GSH)-activated CDT. Qu-Fe NPs had a broad absorption range extending to the NIR region and excellent photothermal conversion ability. After endocytosis into cancer cells, these NPs partially released Qu that downregulated the expression of heat shock protein 70, in turn allowing for LTPTT. Moreover, Qu-Fe NPs could deplete the overexpressed GSH in cancer cells, increasing their sensitivity to reactive oxygen species. Meanwhile, Fe3+could be reduced to Fe2+, which can react with endogenous H2O2to generate hydroxyl radicals to achieve CDT. Heat generated by PTT could further accelerate the Fenton reaction in CDT, thus resulting in the synergistic effects between LTPTT and CDT. Both in vitroand in vivoresults showed that Qu-Fe NPs could effectively inhibit tumor growth. This work presents a new approach for achieving mutually reinforced, synergetic NPs that can be used for LTPTT/CDT combination therapy.

Published
2023
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22. Carbon dot-based fluorescent and colorimetric sensor for sensitive and selective visual detection of benzoyl peroxide

Author

Li, Xiangcao, Xing, Xuejian, Zhao, Shaojing, Zhu, Shaohua, Wang, Benhua, Lan, Minhuan, and Song, Xiangzhi

Abstract

Benzoyl peroxide (BPO) has been added in wheat flour because of its bleaching effect. However, the abnormal used BPO has caused increasing concern due to its strong oxidization capability which may have adverse effects on living organisms. Herein, we present a carbon dot (CD)-based fluorescent and colorimetric probe for visually, sensitively and selectively sensing BPO. The addition of BPO could quench the red fluorescence of CDs peaked at 622 and 677 nm, and decrease the absorbance at 613 nm, while increase the absorbance at 450 nm, resulting in a fluorescence turn-off and colorimetric spectral response. Moreover, the CDs had short response time of 10 min and high sensitivity towards BPO with a low limit of detection of 28 nmol/L. The applicability of the CDs in detecting BPO in wheat, noodle and starch samples was further demonstrated, and good recovery results were obtained.

Published
2021
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