140 results on '"Xie, Yuanchao"'
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2. A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
3. Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model
4. Significant Inhibition of Porcine Epidemic Diarrhea Virus In Vitro by Remdesivir, Its Parent Nucleoside and β-d-N4-hydroxycytidine
5. Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2
6. Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC–MS/MS
7. Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2
8. Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
9. Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer.
10. The complete synthesis of favipiravir from 2-aminopyrazine
11. Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
12. Synthesis and evaluation of NHC derivatives and 4′-fluorouridine prodrugs
13. Synthesis and anti-SARS-CoV-2 activity of deuterated GS-441524 analogs
14. Practical and Highly Efficient Synthesis of Remdesivir from GS-441524
15. Further discovery of caffeic acid derivatives as novel influenza neuraminidase inhibitors
16. Synthesis of cis-4-guanidino-l-proline and 1-carbamimidoyl-l-proline derivatives as influenza neuraminidase inhibitors
17. Research on Common Mode Voltage Suppression Algorithm Based on Three Levels
18. An Active Power Decoupling Topology for Three-phase Four-leg Inverters with Unbalanced Load
19. Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors
20. “One-Pot” Synthesis of Molnupiravir from Cytidine
21. Axial Force Transfer Mechanism of Steel-Concrete Joint in Hybrid Girder for Railway Cable-Stayed Bridge
22. An Improved and Practical Synthesis of Rivaroxaban
23. Development of patch and spray formulations for enhancing topical delivery of sinomenine hydrochloride
24. Synthesis and antiviral activity of 2′‐deoxy‐6′‐substituted carbocyclic nucleosides
25. Discovery of a series of novel compounds with moderate anti-avian H5N1 influenza virus activity in chick embryo
26. Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate
27. A Convenient and Cost Efficient Route Suitable for “One-Pot” Synthesis of Molnupiravir
28. Synthesis and antiviral activity of 2′‐deoxy‐6′‐substituted carbocyclic nucleosides.
29. Structural basis for repurpose and design of nucleoside drugs for treating COVID-19
30. Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
31. Facile synthesis of 2-C-methyl-d-arabino-γ-1,4-lactones and mechanism study
32. Synthesis of CBD and Its Derivatives Bearing Various C4′-Side Chains with a Late-Stage Diversification Method
33. Industry-Oriented Route Evaluation and Process Optimization for the Preparation of Brexpiprazole
34. Discovery of pyrimidine nucleoside dual prodrugs and pyrazine nucleosides as novel anti-HCV agents
35. Continuation of structure–activity relationship study of novel benzamide derivatives as potential antipsychotics
36. Synthesis, structure–activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics
37. A Facile Epoxide Aminolysis Promoted by (t-BuO)2Mg and Its Application to the Synthesis of Efinaconazole
38. Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride
39. A neighboring group participation strategy: facile synthesis of 3,5-di-O-benzoyl-2-C-methyl-d-arabino-γ-lactone
40. Synthesis of CBD and Its Derivatives Bearing Various C4′-Side Chains with a Late-Stage Diversification Method
41. Caffeic acid derivatives: A new type of influenza neuraminidase inhibitors
42. Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review
43. Special Features of the Operator Training Simulator for Coal-Fired Power Plant
44. Discovery of N-Substituted Oseltamivir Derivatives as Potent and Selective Inhibitors of H5N1 Influenza Neuraminidase
45. Synthesis of cis-4-guanidino-l-proline and 1-carbamimidoyl-l-proline derivatives as influenza neuraminidase inhibitors
46. Progress of HDAC Inhibitor Panobinostat in the Treatment of Cancer
47. ChemInform Abstract: Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration
48. Synthesis and crystal structure of 6-fluoro-3-hydroxypyrazine-2-carboxamide
49. Identification, synthesis, and control of efinaconazole impurities
50. Alkylboronate Synthesis Based on Transition Metal-Catalyzed Hydroboration.
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