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Effectively utilizing extensive unlabeled high-density EEG data to improve performance in scenarios with limited labeled low-density EEG data presents a significant challenge. In this paper, we address this by framing it as a graph transfer learning and knowledge distillation problem. We propose a Unified Pre-trained Graph Contrastive Masked Autoencoder Distiller, named EEG-DisGCMAE, to bridge the gap between unlabeled/labeled and high/low-density EEG data. To fully leverage the abundant unlabeled EEG data, we introduce a novel unified graph self-supervised pre-training paradigm, which seamlessly integrates Graph Contrastive Pre-training and Graph Masked Autoencoder Pre-training. This approach synergistically combines contrastive and generative pre-training techniques by reconstructing contrastive samples and contrasting the reconstructions. For knowledge distillation from high-density to low-density EEG data, we propose a Graph Topology Distillation loss function, allowing a lightweight student model trained on low-density data to learn from a teacher model trained on high-density data, effectively handling missing electrodes through contrastive distillation. To integrate transfer learning and distillation, we jointly pre-train the teacher and student models by contrasting their queries and keys during pre-training, enabling robust distillers for downstream tasks. We demonstrate the effectiveness of our method on four classification tasks across two clinical EEG datasets with abundant unlabeled data and limited labeled data. The experimental results show that our approach significantly outperforms contemporary methods in both efficiency and accuracy., Comment: 24 pages

Neuroimaging techniques including functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) have shown promise in detecting functional abnormalities in various brain disorders. However, existing studies often focus on a single domain or modality, neglecting the valuable complementary information offered by multiple domains from both fMRI and EEG, which is crucial for a comprehensive representation of disorder pathology. This limitation poses a challenge in effectively leveraging the synergistic information derived from these modalities. To address this, we propose a Multi-modal Cross-domain Self-supervised Pre-training Model (MCSP), a novel approach that leverages self-supervised learning to synergize multi-modal information across spatial, temporal, and spectral domains. Our model employs cross-domain self-supervised loss that bridges domain differences by implementing domain-specific data augmentation and contrastive loss, enhancing feature discrimination. Furthermore, MCSP introduces cross-modal self-supervised loss to capitalize on the complementary information of fMRI and EEG, facilitating knowledge distillation within domains and maximizing cross-modal feature convergence. We constructed a large-scale pre-training dataset and pretrained MCSP model by leveraging proposed self-supervised paradigms to fully harness multimodal neuroimaging data. Through comprehensive experiments, we have demonstrated the superior performance and generalizability of our model on multiple classification tasks. Our study contributes a significant advancement in the fusion of fMRI and EEG, marking a novel integration of cross-domain features, which enriches the existing landscape of neuroimaging research, particularly within the context of mental disorder studies.

ENN Science and Technology Development Co., Ltd. (ENN) is committed to generating fusion energy in an environmentally friendly and cost-effective manner, which requires abundant aneutronic fuel. Proton-boron ( p-$^{11}$B or p-B) fusion is considered an ideal choice for this purpose. Recent studies have suggested that p-B fusion, although challenging, is feasible based on new cross-section data, provided that a hot ion mode and high wall reflection can be achieved to reduce electron radiation loss. The high beta and good confinement of the spherical torus (ST) make it an ideal candidate for p-B fusion. By utilizing the new spherical torus energy confinement scaling law, a reactor with a major radius $R_0=4$ m, central magnetic field $B_0=6$ T, central temperature $T_{i0}=150$ keV, plasma current $I_p=30$ MA, and hot ion mode $T_i/T_e=4$ can yield p-B fusion with $Q>10$. A roadmap for p-B fusion has been developed, with the next-generation device named EHL-2. EHL stands for ENN He-Long, which literally means ``peaceful Chinese Loong". The main target parameters include $R_0\simeq1.05$ m, $A\simeq1.85$, $B_0\simeq3$ T, $T_{i0}\simeq30$ keV, $I_p\simeq3$ MA, and $T_i/T_e\geq2$. The existing ST device EXL-50 was simultaneously upgraded to provide experimental support for the new roadmap, involving the installation and upgrading of the central solenoid, vacuum chamber, and magnetic systems. The construction of the upgraded ST fusion device, EXL-50U, was completed at the end of 2023, and it achieved its first plasma in January 2024. The construction of EHL-2 is estimated to be completed by 2026., Comment: 16 pages, 8 figures

Fusion reactivity represents the integration of fusion cross-sections and the velocity distributions of two reactants. In this study, we investigate the upper bound of fusion reactivity for a non-thermal reactant coexisting with a thermal Maxwellian background reactant while maintaining a constant total energy. Our optimization approach involves fine-tuning the velocity distribution of the non-thermal reactant. We employ both Lagrange multiplier and Monte Carlo methods to analyze Deuterium-Tritium (D-T) and Proton-Boron11 (p-B11) fusion scenarios. Our findings demonstrate that, within the relevant range of fusion energy, the maximum fusion reactivity can often surpass that of the conventional Maxwellian-Maxwellian reactants case by a substantial margin, ranging from 50\% to 300\%. These enhancements are accompanied by distinctive distribution functions for the non-thermal reactant, characterized by one or multiple beams. These results not only establish an upper limit for fusion reactivity but also provide valuable insights into augmenting fusion reactivity through non-thermal fusion, which holds particular significance in the realm of fusion energy research., Comment: 11 pages, 10 figures

A novel intense beam-driven scheme for high yield of the tri-alpha reaction 11B(p,{\alpha})2{\alpha} was investigated. We used a foam target made of cellulose triacetate (TAC, C_9H_{16}O_8) doped with boron. It was then heated volumetrically by soft X-ray radiation from a laser heated hohlraum and turned into a homogenous, and long living plasma. We employed a picosecond laser pulse to generate a high-intensity energetic proton beam via the well-known Target Normal Sheath Acceleration (TNSA) mechanism. We observed up to 10^{10}/sr {\alpha} particles per laser shot. This constitutes presently the highest yield value normalized to the laser energy on target. The measured fusion yield per proton exceeds the classical expectation of beam-target reactions by up to four orders of magnitude under high proton intensities. This enhancement is attributed to the strong electric fields and nonequilibrium thermonuclear fusion reactions as a result of the new method. Our approach shows opportunities to pursue ignition of aneutronic fusion.