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1. Hydrogel-Based Oxygen and Drug Delivery Dressing for Improved Wound Healing

Author: Wen Ren, Mia Sands, Xiaoxue Han, Michael Tsipursky, and Joseph Irudayaraj
Subjects: Chemistry, QD1-999
Published: 2024
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2. The 8th AJCC classification is inferior to a new neck stage based on intraparotid lymph node in parotid gland cancer

Author: Xiaoxue Han, Changyu Yang, Xuexin Tan, and Yuexiao Li
Subjects: Parotid cancer, Intraparotid lymph node, Extranodal extension, Lymph node burden, AJCC, Dentistry, RK1-715
Abstract: Abstract Background Lymph node (LN) status is an important prognostic factor for parotid gland cancer (PGC). This study aimed to analyze the impact of extranodal extension (ENE) of intraparotid LN and LN metastasis burden on survival in PGC. Methods Patients with surgically treated PGC and at least one metastatic cervical LN were retrospectively enrolled. Primary outcome variables were distant metastasis-free survival (DMFS), disease-specific survival (DSS), and overall survival (OS). The impact of ENE and LN metastasis burden was assessed using the Cox model. Results A total of 292 patients were included. ENE in cervical or intraparotid LN was not associated with DMFS, DSS, or OS. Intraparotid LN metastasis had a significant impact on prognosis, and the presence of only one metastatic intraparotid LN offered an approximately 1.5-fold risk of distant metastasis. Prognostic models based on the number of positive LNs (1 vs. 2–3 vs. 4+) were superior to the AJCC N stage in terms of DMFS, DSS, and OS. Conclusions ENE of cervical or intraparotid LN has a limited effect on the prognosis of PGC, and the number of positive LNs is better than the AJCC N stage in LN status evaluation.
Published: 2024
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3. Nano oxygen chamber by cascade reaction for hypoxia mitigation and reactive oxygen species scavenging in wound healing

Author: Xiaoxue Han, Leah Ju, Chai Saengow, Wen Ren, Randy Ewoldt, Timothy Fan, and Joseph Irudayaraj
Subjects: Hypoxia, ROS scavenging, Anti-inflammation, Oxygen nanobubble, Scarless wound healing, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5
Abstract: Hypoxia, excessive reactive oxygen species (ROS), and impaired angiogenesis are prominent obstacles to wound healing following trauma and surgical procedures, often leading to the development of keloids and hypertrophic scars. To address these challenges, a novel approach has been proposed, involving the development of a cascade enzymatic reaction-based nanocarriers-laden wound dressing. This advanced technology incorporates superoxide dismutase modified oxygen nanobubbles and catalase modified oxygen nanobubbles within an alginate hydrogel matrix. The oxygen nano chamber functions through a cascade reaction between superoxide dismutase and catalase, wherein excessive superoxide in the wound environment is enzymatically decomposed into hydrogen peroxide, and this hydrogen peroxide is subsequently converted into oxygen by catalase. This enzymatic cascade effectively controls wound inflammation and hypoxia, mitigating the risk of keloid formation. Concurrently, the oxygen nanobubbles release oxygen continuously, thus providing a sustained supply of oxygen to the wound site. The oxygen release from this dynamic system stimulates fibroblast proliferation, fosters the formation of new blood vessels, and contributes to the overall wound healing process. In the rat full-thickness wound model, the cascade reaction-based nano oxygen chamber displayed a notable capacity to expedite wound healing without scarring. Furthermore, in the pilot study of porcine full-thickness wound healing, a notable acceleration of tissue repair was observed in the conceived cascade reaction-based gel treated group within the 3 days post-surgery, which represents the proliferation stage of healing process. These achievements hold significant importance in ensuring the complete functional recovery of tissues, thereby highlighting its potential as a promising approach for enhancing wound healing outcomes.
Published: 2024
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4. Exosome-coated oxygen nanobubble-laden hydrogel augments intracellular delivery of exosomes for enhanced wound healing

Author: Xiaoxue Han, Chaimongkol Saengow, Leah Ju, Wen Ren, Randy H. Ewoldt, and Joseph Irudayaraj
Subjects: Science
Abstract: Abstract Wound healing is an obvious clinical concern that can be hindered by inadequate angiogenesis, inflammation, and chronic hypoxia. While exosomes derived from adipose tissue-derived stem cells have shown promise in accelerating healing by carrying therapeutic growth factors and microRNAs, intracellular cargo delivery is compromised in hypoxic tissues due to activated hypoxia-induced endocytic recycling. To address this challenge, we have developed a strategy to coat oxygen nanobubbles with exosomes and incorporate them into a polyvinyl alcohol/gelatin hybrid hydrogel. This approach not only alleviates wound hypoxia but also offers an efficient means of delivering exosome-coated nanoparticles in hypoxic conditions. The self-healing properties of the hydrogel, along with its component, gelatin, aids in hemostasis, while its crosslinking bonds facilitate hydrogen peroxide decomposition, to ameliorate wound inflammation. Here, we show the potential of this multifunctional hydrogel for enhanced healing, promoting angiogenesis, facilitating exosome delivery, mitigating hypoxia, and inhibiting inflammation in a male rat full-thickness wound model.
Published: 2024
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5. Association between serum uric acid/high-density lipoprotein cholesterol ratio and hypertension among reproductive-aged women

Author: Xiaoxue Han, Xuan Tan, Mengyuan Liu, Yiling Wei, Andong He, Ying Pan, Di Qiu, and Ruiman Li
Subjects: High-density lipoprotein cholesterol, Hypertension, Nutrition surveys, Inflammation, Women, Nutritional diseases. Deficiency diseases, RC620-627, Public aspects of medicine, RA1-1270
Abstract: Abstract Background Uric acid/high-density lipoprotein cholesterol ratio (UHR) is a novel index of inflammation and metabolism that has been investigated in various diseases. However, association between UHR and hypertension among reproductive-aged women is unclear. Methods In this cross-sectional study, we investigated the association between serum UHR and hypertension among 5485 women aged 20–44 years based on the National Health and Nutrition Examination Survey (NHANES) database using various methods, including univariate and multivariate logistic regression analysis, stratified analysis, and spline regression. P 1, P
Published: 2023
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6. Regulating electronic environment on alkali metal-doped Cu@NS-SiO2 for selective anisole hydrodeoxygenation

Author: Xiaofei Wang, Xiaoxue Han, Li Kang, Shixiang Feng, Meiyan Wang, Yue Wang, Shouying Huang, Yujun Zhao, Shengping Wang, and Xinbin Ma
Subjects: Anisole, Hydrodeoxygenation, Arenes, Alkali metal, Electronic effect, Chemical engineering, TP155-156, Biochemistry, QD415-436
Abstract: Lignin utilization is a potential approach for replacing fossil energy and releasing the environment pressure. Herein, we synthesized a series of novel Cu-based catalysts, Cu@NS-SiO2 (NS = nano sphere) and alkali metals (Na, K, Rb, and Cs) doped Cu@NS-SiO2, and applied them in hydrodeoxygenation reaction of anisole. High Cu dispersion was presented on all catalysts. The modification of alkali metals on Cu@NS-SiO2 significantly enhanced the electron density of Cu sites in the following order: Cs > Rb > K > Na, among which Cs decreased the Cu 2p3/2 binding energy most (by 0.7 eV). Moreover, the modification did not substantially affect the geometric structure of Cu species. This regulable electronic environment of Cu sites was crucial for selective deoxygenation and inhibiting the hydrogenation of aromatic rings in anisole, and thus promoted the selectivity of benzene. Compared with Cu@NS-SiO2 (∼59%), the highest benzene selectivity was obtained on Cs/10Cu@NS-SiO2 at ∼83%.
Published: 2023
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7. Bounds of Eigenvalues for Complex q-Sturm–Liouville Problem

Author: Xiaoxue Han
Subjects: complex q-Sturm–Liouville problem, complex valued coefficient, non-real eigenvalue, upper bounds, lower bounds, Mathematics, QA1-939
Abstract: The eigenvalues of complex q-Sturm–Liouville boundary value problems are the focus of this paper. The coefficients of the corresponding q-Sturm–Liouville equation provide the lower bounds on the real parts of all eigenvalues, and the real part of the eigenvalue and the coefficients of this q-Sturm–Liouville equation provide the bounds on the imaginary part of each eigenvalue.
Published: 2024
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8. Intraparotid lymph node metastasis affects distant metastasis in parotid adenoid cystic carcinoma

Author: Xiaoxue Han, Jia Wang, Yuexiao Li, Shanlong Xi, and Weiwei Xiao
Subjects: Medicine, Science
Abstract: Abstract To evaluate the relationship between factors of metastatic intraparotid lymph node (IPLN) and distant metastasis in parotid adenoid cystic carcinoma (ACC). Patients with surgically treated parotid ACC were retrospectively enrolled, and primary outcome variable was distant metastasis free survival (DMFS). The effect of factors of metastatic IPLN on DMFS was evaluated using Cox model. In total, 232 patients were included. Extranodal extension of IPLN and cervical lymph nodes did not impact the DMFS, and the 7th but not 8th AJCC N stage was associated with DMFS. Groups of 0 and 1 metastatic IPLN had comparable DMFS, but presence of 2+ positive IPLN was related to increased worse DMFS (p = 0.034, HR 2.09). A new N stage (0 vs 1–2 vs 3+) based on total positive lymph node number exhibited better C-index than traditional N stage. IPLN metastasis increased the risk of distant metastasis, and the impact was mainly determined by the number of metastatic IPLN. Our proposed N stage provided better DMFS prediction than the 8th AJCC N classification.
Published: 2023
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9. High glucose inhibits neural differentiation by excessive autophagy via peroxisome proliferator-activated receptor gamma

Author: Yin Pan, Di Qiu, Shu Chen, Xiaoxue Han, and Ruiman Li
Subjects: high glucose, neural differentiation, autophagy, peroxisome proliferator-activated receptor gamma, P19 cells, Biology (General), QH301-705.5
Abstract: The high prevalence of prediabetes and diabetes globally has led to the widespread occurrence of severe complications, such as diabetic neuropathy, which is a result of chronic hyperglycemia. Studies have demonstrated that maternal diabetes can lead to neural tube defects by suppressing neurogenesis during neuroepithelium development. While aberrant autophagy has been associated with abnormal neuronal differentiation, the mechanism by which high glucose suppresses neural differentiation in stem cells remains unclear. Therefore, we developed a neuronal cell differentiation model of retinoic acid induced P19 cells to investigate the impact of high glucose on neuronal differentiation in vitro. Our findings indicate that high glucose (HG) hinders neuronal differentiation and triggers excessive. Furthermore, HG treatment significantly reduces the expression of markers for neurons (Tuj1) and glia (GFAP), while enhancing autophagic activity mediated by peroxisome proliferator-activated receptor gamma (PPARγ). By manipulating PPARγ activity through pharmacological approaches and genetically knocking it down using shRNA, we discovered that altering PPARγ activity affects the differentiation of neural stem cells exposed to HG. Our study reveals that PPARγ acts as a downstream mediator in high glucose-suppressed neural stem cell differentiation and that refining autophagic activity via PPARγ at an appropriate level could improve neuronal differentiation efficiency. Our data provide novel insights and potential therapeutic targets for the clinical management of gestational diabetes mellitus.
Published: 2023
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10. Preparation and Properties of Graft-Modified Bagasse Cellulose/Polylactic Acid Composites

Author: Yanan Wang, Hao Xu, Lijie Huang, Xiaoxue Han, Zhehao Wei, Qi Mo, Xiyue Wang, and Yishan Li
Subjects: bagasse cellulose, polylactic acid, graft modification, polymer-matrix composites, modified fiber, bio composite, Science, Textile bleaching, dyeing, printing, etc., TP890-933
Abstract: Fiber reinforcement is the most common method for modifying polylactic acid (PLA). However, poor compatibility between fibers and PLA, especially at high cellulose contents, can promote cellulose agglomeration in the continuous phase, which damages the mechanical properties of composite materials. To address these issues, bagasse cellulose (BC) was used as a substrate and bifunctional glycidyl methacrylate (GMA) was used as a reactive monomer for graft modification. GMA-modified BC (BC-GMA)/PLA composite materials with different particle sizes were prepared using a blending grafting method, and the influence of the type and content of BC-GMA on the mechanical properties of the composite materials was explored. During the grafting modification of BC, a longer reaction time was found to result in smaller BC particles and a higher degree of grafting. For BC-GMA, the degree of grafting reached 27.02% with a maximum thermal decomposition temperature of 359.31°C. Furthermore, the BC-GMA/PLA composite material had a greater relative crystallinity of PLA, indicating that BC-GMA was evenly dispersed in the continuous phase. This study demonstrates that grafting modification can successfully achieve high cellulose loading in composite materials and thus reduce the production costs of PLA-based packaging materials.
Published: 2023
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11. Ferroptosis-related gene expression in the pathogenesis of preeclampsia

Author: Yuzhen Ding, Xiaofeng Yang, Xiaoxue Han, Meiting Shi, Lu Sun, Mengyuan Liu, Ping Zhang, Zhengrui Huang, Xiuli Yang, and Ruiman Li
Subjects: preeclampsia, ferroptosis, placenta, bioinformatics, WGCNA, Genetics, QH426-470
Abstract: Background: Preeclampsia (PE) is one of the leading causes of maternal and fetal morbidity and mortality worldwide. Placental oxidative stress has been identified as a major pathway to the development of PE. Ferroptosis is a new form of regulated cell death that is associated with iron metabolism and oxidative stress, and likely mediates PE pathogenesis. The aim of the study was to identify the key molecules involved in ferroptosis to further explore the mechanism of ferroptosis in PE.Methods: Gene expression data and clinical information were downloaded from the GEO database. The limma R package was used to screen differentially expressed genes (DEGs) and intersected with ferroptosis genes. The GO and KEGG pathways were then analyzed. Next, hub genes were identified via weighted gene co-expression network analysis (WGCNA). Receiver operating curves (ROCs) were performed for diagnostic and Pearson’s correlation of hub genes and clinicopathological characteristics. Immunohistochemistry and Western blot analysis were used to verify the expression of hub genes.Results: A total of 3,142 DEGs were identified and 30 ferroptosis-related DEGs were obtained. In addition, ferroptosis-related pathways were enriched by GO and KEGG using DEGs. Two critical modules and six hub genes that were highly related to diagnosis of PE were identified through WGCNA. The analysis of the clinicopathological features showed that NQO1 and SRXN1 were closely correlated with PE characteristics and diagnosis. Finally, Western blot and immunohistochemistry analysis confirmed that the expression of the SRXN1 protein in the placental tissue of patients with PE was significantly elevated, while the expression of NQO1 was significantly decreased.Conclusions: SRXN1 and NQO1 may be key ferroptosis-related proteins in the pathogenesis of PE. The study may provide a theoretical and experimental basis for revealing the pathogenesis of PE and improving the diagnosis of PE.
Published: 2022
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12. Effect of chlorine dioxide with NaH2PO4 and DMSO on bleaching of kraft pine pulp

Author: Lijie Huang, Zhehao Wei, Yanan Wang, Xiaoxue Han, Haobin Chen, Chongxing Huang, and Yingnan Wei
Subjects: Physics, QC1-999
Abstract: In this paper, the effect of D0 temperature, Kappa factor and the final pH value on bleaching sulfate bleached pine wood pulp was studied. The results showed that the bleaching efficiency was better when the pH value was 4, and the amount of absorbable organic halogen (AOX) in the bleaching wastewater was decreased. The Kappa factor is linear with the whiteness in the range of 0–0.15. With the increase of the Kappa factor, the amount of AOX in bleaching wastewater of D0 and Ep gradually increases. High temperature bleaching can reduce AOX production, but some fibers are hydrolyzed, leading to a decrease in pulp viscosity. The effects of chlorine dioxide solution adding sodium dihydrogen phosphate (NaH2PO4) and dimethylsulfoxide (DMSO) on pulp bleaching were investigated. The results showed that both solutions could reduce the amount of AOX in bleaching wastewater. Among them, the addition of NaH2PO4 in chlorine dioxide increased pulp whiteness, while the addition of DMSO was the opposite. Scanning electron microscope showed that a small amount of hollow cracks and more voids appeared on the surface of pulp fibers after the addition of NaH2PO4. Pulp fibers bleached by the chlorine dioxide adding DMSO have more folds and less voids on the surface. The surface wrinkles of pulp fibers increased with the addition of DMSO and the voids were less. FT-IR showed that the number of chromophore groups in the pulp bleached by chlorine dioxide adding NaH2PO4 were decreased. However, the lignin characteristic absorption peak in the pulp bleached by chlorine dioxide adding DMSO increased at the intensity of 1062 and 1160 cm−1, which indicated that there were more residual chromophore groups.
Published: 2021
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13. Synthesis and Characterization of Starch-Based Acid- and Alkali-Resistant Hydrogels Optimized by Box–Behnken Response Surface Methodology

Author: Xiaoxue Han, Lijie Huang, Qi Mo, Zhehao Wei, Yanan Wang, Yishan Li, Chongxing Huang, Qingshan Duan, and Yingnan Wei
Subjects: hydrogels, mechanical properties, response surfaces, acid and alkali resistance, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65
Abstract: Applying gel-type solid chlorine dioxide for the sustained release of chlorine dioxide has several shortcomings, such as no resistance to acid and alkali corrosion and poor mechanical properties. However, introducing quaternary ammonium, carboxyl, and amino groups into the hydrogel system can enhance its acid and alkali resistance. In this study, the effects of concentration of dry heat-modified starch, quaternized carboxymethyl cellulose, and chitin on the swelling behavior and mechanical properties of starch-based acid- and alkali-resistant hydrogels are investigated. The feasibility of the actual and predicted values of the tentative results is verified based on the response surface design to determine the optimal concentration ratio of acid- and alkali-resistant hydrogels. The results reveal that optimized process parameters are reliable. The maximum swelling ratio and compressive stress of the hydrogel are 5358.00% and 44.45 kPa, respectively, and its swelling behavior conforms to the pseudo second-order kinetic model. Thus, the present study can provide a new method of developing efficient starch-based chlorine dioxide hydrogels for the sustained release of chlorine dioxide.
Published: 2022
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14. Ferroptosis-Related Proteins Are Potential Diagnostic Molecular Markers for Patients with Preeclampsia

Author: Meiting Shi, Xiaofeng Yang, Yuzhen Ding, Lu Sun, Ping Zhang, Mengyuan Liu, Xiaoxue Han, Zhengrui Huang, and Ruiman Li
Subjects: preeclampsia, ferroptosis, bioinformatics, diagnosis, Biology (General), QH301-705.5
Abstract: Preeclampsia (PE) is the leading cause of maternal and fetal mortality and morbidity. Early and accurate diagnosis is critical to reduce mortality. Placental oxidative stress has been identified as a major pathway to the development of PE. Ferroptosis, a new form of regulated cell death, is associated with iron metabolism and oxidative stress, and has been suspected to play a role in the pathophysiology of PE, although the mechanism is yet to be elucidated. The identification of potential ferroptosis-related biomarkers is of great significance for the early diagnosis and treatment of PE. A gene expression dataset of peripheral blood samples was downloaded from the Gene Expression Omnibus (GEO) dataset. Differentially expressed genes (DEGs) were filtrated with the R package “limma”. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of the DEGs were then conducted. Ferroptosis-related DEGs were screened by overlapping the ferroptosis-related genes with DEGs. The protein–protein interaction (PPI) network was used to identify the key ferroptosis-related DEGs. Enzyme-linked immunosorbent assay (ELISA) was used to validate changes in the selected key ferroptosis-related DEGs. The correlations between the key genes and clinical and pathological characteristics were analyzed. Finally, the diagnostic value of these key genes for PE was confirmed by a receiver operating characteristic (ROC) curve. A total of 5913 DEGs were identified and 45 ferroptosis-related DEGs were obtained. Besides, ferroptosis-related pathways were enriched by KEGG using DEGs. The PPI network showed that p53 and c-Jun were the critical hub genes. ELISA showed that p53 in the serum of PE patients was higher than that of the control group, while c-Jun was lower than that of the control group. Analysis of the clinicopathological features showed that p53 and c-Jun were correlated with the PE characteristics. Finally, based on the area under curve (AUC) values, c-Jun had the superior diagnostic power (AUC = 0.87, p < 0.001), followed by p53 (AUC = 0.75, p < 0.001). Our study identified that two key genes, p53 and c-Jun, might be potential diagnostic biomarkers of PE.
Published: 2022
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15. Synthesis and Optimization of a Free-Radical/Cationic Hybrid Photosensitive UV Curable Resin Using Polyurethane Acrylate and Graphene Oxide

Author: Lijie Huang, Yanan Wang, Zhehao Wei, Xiaoxue Han, Qi Mo, Xiyue Wang, and Yishan Li
Subjects: photosensitive resin, orthogonal experiments, polyurethane acrylates, graphene oxide, tensile strength, gelation rate, Organic chemistry, QD241-441
Abstract: Cost-effective, practical, and efficiently performing photosensitive resin composite materials are essential, as the current materials are expensive, lack better alternatives, and do not meet 3D printing standards. In this study, based on orthogonal experiments for photosensitive resin curing, we prepared a free-radical/cationic hybrid photosensitive UV cured resin (UVR) using acrylic ester and epoxy resin as the prepolymers, tripropylenediol diacrylate (TPGDA) as the active diluent, and triaryl sulfonium salt (I-160) and 2,2-dimethyl-α-hydroxy acetophenone (1173) as the photoinitiators, in the optimized formula of acrylic-ester:epoxy-resin:TPGDA:I-160:1173 = 37.5:37.5:20:2.5:2.5. Further, we investigated the effects of polyurethane acrylates (PUA) and Graphene oxide (GO) on the surface morphology, chemical structure, hydrophobicity, mechanical strength, and gelation rate of the hybrid resin. We observed that 20% PUA improved tensile strength to the maximum of 36.89 MPa from 16.42 MPa of the unmodified hybrid resin, whereas 1% GO reduced volume shrinkage to the minimum of 2.89% from 3.73% of the unmodified hybrid resin. These photosensitive resins with higher tensile strength and lower volume shrinkage can be used to synthesize high performance functional materials in the future.
Published: 2022
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16. Potential Effect of COVID-19 on Maternal and Infant Outcome: Lesson From SARS

Author: Yun Wang, Yiliang Wang, Xiaoxue Han, Jiazhuo Ye, and Ruiman Li
Subjects: COVID-19, SARS-CoV-2, maternal outcome, infant outcome, SARS-CoV, Pediatrics, RJ1-570
Abstract: The coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is highly infectious and its ongoing outbreak has been declared a global pandemic by the WHO. Pregnant women are susceptible to respiratory pathogens and the development of severe pneumonia, suggesting the urgent need to assess the potential maternal and infant outcome of pregnancy with COVID-19. The intrauterine vertical transmission potential of SARS-CoV-2 also remains controversial. Herein, we discuss the potential effect of COVID-19 on maternal and infant outcomes based on current studies, including those published in Chinese, in a total of 80 mothers with COVID-19 and 80 infants. We also comprehensively explored the mother-to-child transmission routes of SARS-CoV-2, in particular the route of intrauterine vertical transmission. Given SARS-CoV-2 is a sister to SARS-CoV, of the SARS-related coronavirus species, we made a comprehensive comparison between them to learn from experiences with SARS. Although there is no evidence supporting the intrauterine vertical transmission of SARS-CoV-2, our comprehensive analysis suggests that the adverse maternal and infant outcomes caused by COVID-19 cannot be underestimated. Further, we speculated that the inconsistency between nucleic acids and serological characteristics IgM to SARS-CoV-2 of infants' specimens may be caused by the disruption of the amniotic barrier by the inflammatory factors induced by SARS-CoV-2 infection. Our review is beneficial to understand the effect of SARS-CoV-2 on maternal and infant outcomes.
Published: 2020
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17. Management and prognosis of cancers in the accessory parotid gland

Author: Xiaoxue Han, Xifeng Zhang, Yuqin Gao, Pai Pang, Fayu Liu, and Changfu Sun
Subjects: Medicine (General), R5-920
Abstract: Objective This study was performed to analyze the clinical management of accessory parotid gland (APG) cancer and possible risk factors for disease-related death. Methods Patients diagnosed with primary APG cancers in the largest medical center in Northeast China were enrolled from January 1990 to December 2016. Results All 43 patients underwent resection of the tumors and superficial parotid gland by a standard Blair incision. Seven (16.3%) patients also required selective neck dissection. The most common lesion was mucoepidermoid carcinoma. Temporary facial paralysis occurred in 11 (25.6%) patients, and permanent facial paralysis occurred in 3 (7.0%) patients because of surgical resection of the facial nerve, which was involved with the tumor. The 5- and 10-year disease-specific survival rates were 86.0% and 66.0%, respectively. The tumor stage, neck status, neck dissection, and tumor grade were significantly associated with disease-related death, but only the tumor grade was an independent risk factor. Conclusion Superficial parotidectomy is a reliable surgical procedure associated with a high survival rate and low morbidity in treating APG cancers. The tumor grade is the key prognostic factor.
Published: 2018
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18. Preparation and Barrier Performance of Layer-Modified Soil-Stripping/Cassava Starch Composite Films

Author: Lijie Huang, Xiaoxue Han, Haobin Chen, Shuxiang An, Hanyu Zhao, Hao Xu, Chongxing Huang, Shuangfei Wang, and Yang Liu
Subjects: montmorillonite, intercalation reaction, starch film, barrier mechanism, Organic chemistry, QD241-441
Abstract: In this study, we investigated the barrier properties of a montmorillonite-reinforced biomass material, starch. Organically modified montmorillonite materials were prepared from natural montmorillonite by reacting it with dodecyl trimethyl ammonium chloride, dodecyl dimethyl benzyl ammonium chloride or octadecyl trimethyl ammonium chloride under ultrasonic conditions. The composite starch films incorporated with these organically modified montmorillonite samples were characterized by scanning electron microscopy, transmission electron microscopy, infrared spectroscopy and X-ray diffraction. The results showed that the introduction of montmorillonite decreases the transmittance of the composite film by 10% in the visible region and significantly inhibits UV-light transmittance. The decomposition temperature of the composite film ranges from 200 to 500 °C, with a weight loss rate of 80%. The distance between the montmorillonite layers increases from 0.14 nm in the non-magnetized state to 1.49 nm after magnetization. The oxygen permeability of the starch film modified by organic montmorillonite (0.067 cm3/m2·d) is lower than that of the montmorillonite starch film without magnetization (0.097cm3/m2·d). The oxygen barrier capacity is close to zero. Particularly in the ordered magnetic montmorillonite starch composite film, the oxygen barrier ability is the best. Therefore, modified montmorillonite could serve as an excellent reinforcing agent for cassava starch films and effectively improve the oxygen barrier performance of the films.
Published: 2020
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19. Effect of different surface modified nanoparticles on viscosity of nanofluids

Author: Shenghan Zhang and Xiaoxue Han
Subjects: Mechanical engineering and machinery, TJ1-1570
Abstract: Resistance to fluid flow creates various problems, and fluid viscosity reduction can effectively control these problems. Hydrophilic TiO 2 -water and hydrophilic-lipophilic TiO 2 -water nanofluids were prepared by stirring and ultrasonic mixing; the rotational viscometer was used to measure the viscosity of nanofluids that formed by different surface modifications of nano-titanium dioxide and deionized water. The results show that the viscosity of TiO 2 -water nanofluid increases with the decrease in the temperature and increase in the mass fraction of nanoparticles, the hydrophilic TiO 2 -water nanofluids has a slightly larger viscosity than the hydrophilic-lipophilic TiO 2 -water nanofluids, and the higher the mass fraction of the nanoparticles is, the greater the difference is.
Published: 2018
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20. Text-enhanced Multi-Granularity Temporal Graph Learning for Event Prediction.

Author: Xiaoxue Han and Yue Ning 0001
Published: 2022
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21. Visual analysis based on the research of SARS and COVID-19: a 20-year bibliometric study.

Author: Qifang Liang, Buping Liu, Chunping Liu, Wenxing Liu, Xiaoxue Han, Limei Wan, Xiaobo Chen, Peng wu, Hongyu Li, Yujiao Sun, Yubin Yang, and Weixiong Chen
Published: 2021
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22. Overexpressed Trophoblast Glycoprotein Contributes to Preeclampsia Development by Inducing Abnormal Trophoblast Migration and Invasion Toward the Uterine Spiral Artery.

Author: Lu Sun, Meiting Shi, Jian Wang, Xiaoxue Han, Jiachun Wei, Zhengrui Huang, Xiaofeng Yang, Yuzhen Ding, Ping Zhang, Andong He, Mengyuan Liu, Ruiling Yan, Xuesong Yang, Ruiman Li, and Guang Wang
Abstract: BACKGROUND: Preeclampsia is a significant pregnancy disorder with an unknown cause, mainly attributed to impaired spiral arterial remodeling. METHODS: Using RNA sequencing, we identified key genes in placental tissues from healthy individuals and preeclampsia patients. Placenta and plasma samples from pregnant women were collected to detect the expression of TPBG (trophoblast glycoprotein). Pregnant rats were injected with TPBG-carrying adenovirus to detect preeclamptic features. HTR-8/SVneo cells transfected with a TPBG overexpression lentiviral vector were used in cell function experiments. The downstream molecular mechanisms of TPBG were explored using RNA sequencing and single-cell RNA sequencing data. TPBG expression was knocked down in the lipopolysaccharide-induced preeclampsia-like rat model to rescue the preeclampsia features. We also assessed TPBG’s potential as an early preeclampsia predictor using clinical plasma samples. RESULTS: TPBG emerged as a crucial differentially expressed gene, expressed specifically in syncytiotrophoblasts and extravillous trophoblasts. Subsequently, we established a rat model with preeclampsia-like phenotypes by intravenously injecting TPBG-expressing adenoviruses, observing impaired spiral arterial remodeling, thus indicating a causal correlation between TPBG overexpression and preeclampsia. Studies with HTR-8/SVneo cells, chorionic villous explants, and transwell assays showed TPBG overexpression disrupts trophoblast/extravillous trophoblast migration/invasion and chemotaxis. Notably, TPBG knockdown alleviated the lipopolysaccharide-induced preeclampsia-like rat model. We enhanced preeclampsia risk prediction in early gestation by combining TPBG expression with established clinical predictors. CONCLUSIONS: These findings are the first to show that TPBG overexpression contributes to preeclampsia development by affecting uterine spiral artery remodeling. We propose TPBG levels in maternal blood as a predictor of preeclampsia risk. The proposed mechanism by which TPBG overexpression contributes to the occurrence of preeclampsia via its disruptive effect on trophoblast and extravillous trophoblast migration/invasion on uterine spiral artery remodeling, thereby increasing the risk of preeclampsia. [ABSTRACT FROM AUTHOR]
Published: 2024
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23. Applying Item Response Theory to Analyzing and Improving the Item Quality of an Online Chinese Reading Assessment.

Author: Xinyun Tian, Xiaoxue Han, Hercy N. H. Cheng, Wang-Chen Chang, Calvin C. Y. Liao, Jianwen Sun, Xiaoliang Zhu, and Sanya Liu
Published: 2017
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24. Size dependence of carbon-encapsulated iron-based nanocatalysts for Fischer—Trposch synthesis

Author: Xiaoxue Han, Jing Lv, Shouying Huang, Qiao Zhao, Yue Wang, Zhenhua Li, and Xinbin Ma
Subjects: General Materials Science, Electrical and Electronic Engineering, Condensed Matter Physics, Atomic and Molecular Physics, and Optics
Published: 2023

25. Nanocatalase-Based Oxygen-Generating Nanocarriers for Active Oxygen Delivery to Relieve Hypoxia in Pancreatic Cancer

Author: Xiaoxue Han, Yoon Jeong, and Joseph Irudayaraj
Subjects: General Materials Science
Published: 2022

26. Individual Word Length Patterns for Fractional Factorial (Split-Plot) Designs

Author: Xiaoxue Han, Jianbin Chen, Jianfeng Yang, and Minqian Liu
Subjects: Computer Science (miscellaneous), Information Systems
Published: 2023

27. Extremely Low CO/H2 Ratio Activation of a Precipitated Iron Catalyst for Enhanced Fischer–Tropsch Performance

Author: Jiajia Chen, Qiao Zhao, Xiaoxue Han, Jing Lv, Zhenhua Li, Shouying Huang, and Xinbin Ma
Subjects: Fuel Technology, General Chemical Engineering, Energy Engineering and Power Technology
Published: 2022

28. A Monodisperse ε′-(CoxFe1–x)2.2C Bimetallic Carbide Catalyst for Direct Conversion of Syngas to Higher Alcohols

Author: Zhuang Zeng, Zhuoshi Li, Li Kang, Xiaoxue Han, Zouxuan Qi, Shaoxia Guo, Junhu Wang, Alexandre Rykov, Jing Lv, Yue Wang, and Xinbin Ma
Subjects: General Chemistry, Catalysis
Published: 2022

29. Regulating electronic environment on alkali metal-doped Cu@NS-SiO2 for selective anisole hydrodeoxygenation.

Author: Xiaofei Wang, Xiaoxue Han, Li Kang, Shixiang Feng, Meiyan Wang, Yue Wang, Shouying Huang, Yujun Zhao, Shengping Wang, and Xinbin Ma
Subjects: ALKALI metals, ALKALI metal ions, ANISOLE, COPPER, ELECTRON density, FOSSIL fuels, BINDING energy
Abstract: Lignin utilization is a potential approach for replacing fossil energy and releasing the environment pressure. Herein, we synthesized a series of novel Cu-based catalysts, Cu@NS-SiO2 (NS ¼ nano sphere) and alkali metals (Na, K, Rb, and Cs) doped Cu@NS-SiO2, and applied them in hydrodeoxygenation reaction of anisole. High Cu dispersion was presented on all catalysts. The modification of alkali metals on Cu@NS-SiO2 significantly enhanced the electron density of Cu sites in the following order: Cs > Rb > K > Na, among which Cs decreased the Cu 2p3/2 binding energy most (by 0.7 eV). Moreover, the modification did not substantially affect the geometric structure of Cu species. This regulable electronic environment of Cu sites was crucial for selective deoxygenation and inhibiting the hydrogenation of aromatic rings in anisole, and thus promoted the selectivity of benzene. Compared with Cu@NS-SiO2 (~59%), the highest benzene selectivity was obtained on Cs/10Cu@NS-SiO2 at ~83%. [ABSTRACT FROM AUTHOR]
Published: 2023
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30. Autonomous Cricothyroid Membrane Detection and Manipulation Using Neural Networks and a Robot Arm for First-Aid Airway Management

Author: Xiaoxue Han, Hailin Ren, Jingyuan Qi, and Pinhas Ben-Tzvi
Subjects: Biomedical Engineering, Medicine (miscellaneous)
Abstract: Cricothyrotomy serves as one of the most efficient surgical interventions when a patient is enduring a can't intubate can't oxygenate (CICO) scenario. However, medical background and professional training are required for the provider to establish a patent airway successfully. Motivated by robotics applications in search and rescue, this work focuses on applying artificial intelligence techniques to the precise localization of the incision site, the cricothyroid membrane (CTM), of the injured using an RGB-D camera, and the manipulation of a robot arm with reinforcement learning to reach the detected CTM keypoint. In this paper, we proposed a deep learning-based model, the hybrid neural network (HNNet), to detect the CTM with a success rate of 96.6%, yielding an error of less than 5 mm in real-world coordinates. In addition, a separate neural network was trained to manipulate a robotic arm for reaching a waypoint with an error of less than 5 mm. An integrated system that combines both the perception and the control techniques was built and experimentally validated using a human-size manikin to prove the overall concept of autonomous cricothyrotomy with an RGB-D camera and a robotic manipulator using artificial intelligence.
Published: 2023

31. Nature Sunlight-Driven Polymer/Tio2 Antimicrobial Agent for the Killing of Multidrug-Resistant Bacteria with Enhanced Photocatalytic Activity

Author: Juan Du, Simiao Wang, Pingyu Luo, Xiaoxue Han, Xinyue Bai, Enwei Zhu, Chunbo Liu, Haiyong Guo, and Chunhong Ma
Published: 2023

32. On Ordering Problems: A Statistical Approach

Author: Jianbin Chen, Xiaoxue Han, Dennis K.J. Lin, Liuqing Yang, and Yongdao Zhou
Subjects: Statistics and Probability, Statistics, Probability and Uncertainty
Published: 2023

33. Evidence of a J/ψΛ structure and observation of excited Ξ- states in the Ξb-→J/ψΛK- decay

Author: Sergey Legotin, Thomas Peter Jones, Andrea Lampis, Monica Pepe Altarelli, Sergii Kandybei, Eric Cogneras, Alexander Malinin, Mikhail Korolev, Naomi Cooke, Ross John Hunter, Eric van Herwijnen, Dmitry Golubkov, V. Matiunin, Mika Vesterinen, Z. Li, Stephane T'Jampens, S. Filippov, Stephanie Hansmann-Menzemer, Giacomo Graziani, J. A. B. Coelho, Lavinia-Helena Giubega, E. Golobardes, P. J. Marshall, D. Xiao, N. Polukhina, Placido Fernandez Declara, L. Minzoni, Ricardo Vazquez Gomez, David Anthony Friday, Harris Conan Bernstein, Cesar Luiz Da Silva, Jakob Haimberger, Halime Sazak, Vladimir Shevchenko, Maarten van Veghel, Irina Nasteva, George Coombs, Rosen Matev, Suzanne Klaver, Alexandre Boyer, Pablo Baladron Rodriguez, Abraham Gallas Torreira, Elisabeth Maria Niel, Sonia Amina Bouchiba, N. S. Nolte, V. Macko, J. Buytaert, Xianglei Zhu, Ilia Belov, Andreas Schopper, Melissa Maria Cruz Torres, T. Nanut, C. Bozzi, H. Viemann, Aleksandr Petrov, Antonio Falabella, Davide Zuliani, H. Stevens, Jonas Rademacker, Bo Fang, Kristof De Bruyn, F. Ferreira Rodrigues, S. Kotriakhova, Yuehong Xie, Anastasia Smetkina, Peilian Li, Maximo Plo Casasus, John Jake Lane, J. Wang, Marek Jezabek, Giovanni Passaleva, Thi Thuy Hang Pham, Di Yang, Eddy Jans, Roger Barlow, Cheryl Pappenheimer, Lais Soares Lavra, I. A. Monroy, Federico Stagni, Wojciech Kucewicz, S. Jakobsen, Jozef Tomasz Borsuk, Agnieszka Dziurda, Ricardo Graciani Diaz, Yury Guz, Regis Lefèvre, Lucian Cojocariu, Mark Smith, M. Soares, M. Hatch, S. Kretzschmar, Stephen M. Stahl, John Back, M. D. Sokoloff, Simone Bifani, Mark Whitehead, Lucas Mcconnell, Semen Eidelman, A. Usachov, Silvia Borghi, Pavel Krokovny, Mario Edgardo Olivares, Rui Wang, Christopher James Pawley, Lukas Calefice, A. Inglessi, Jose Maria Fernandez-tenllado Arribas, Aleksei Chernov, Davide Fazzini, Stephen Wotton, B. Delaney, S. Meloni, Zakariya Aliouche, M. S. Bieker, G. Morello, Richard Jacobsson, Marta Calvi, Giulia Manca, R. D. Moise, C. Hasse, Ekaterina Trifonova, W. Parker, Valerie Gibson, Patrizia De Simone, Shuaiyi Liu, Marie-Noelle Minard, Clara Gaspar, Massimiliano Fiorini, Miriam Calvo Gomez, Carla Marin Benito, Evgeny Gushchin, Ilaria Neri, Oliver Lupton, W. Huang, Stefano De Capua, Nigel Watson, Alexey Zhelezov, Elena Graverini, B.R. Gruberg Cazon, Amanda May Donohoe, Valeriia Lukashenko, Jean François Marchand, Boleslaw Pietrzyk, Anna Lupato, Carlos Abellán Beteta, Konstantin Belous, Marco Poli Lener, B. Spaan, Daniel Patrick O'Hanlon, Giacomo Vitali, Marco Santimaria, Daniel Decamp, Jairo Alexis Rodriguez Lopez, S. Ponce, Lucio Anderlini, Oscar De Aguiar Francisco, U. Marconi, C. Weisser, S. Tolk, Valery Zhukov, Konrad Klimaszewski, Eliane Epple, Louis Lenard Gerken, S. Ek-In, Adriano Lai, A. Guth, Yutong Li, G. Liu, Miriam Gandelman, S. Monteil, Frederic Teubert, Christopher Burr, Dario de Simone, Michael Schmelling, Paul Andre Günther, J. B. Zonneveld, R. Calabrese, Oleg Stenyakin, A. Szabelski, Anna Danilina, Jakub Ryzka, Timothy Evans, George Lafferty, Marcelo Soares, Patrick Koppenburg, Artur Ukleja, Jose Lopes, Jakub Moron, X. Lyu, Carmen Giugliano, A. Maevskiy, Paolo Gandini, Marcello Rotondo, D. Zhang, Manuel Schiller, Marcos Romero Lamas, S. Schulte, P. Ibis, W. Krupa, S. Cadeddu, Lei Zhang, Simon Stemmle, Katharina Müller, P. Stefko, Philipp Roloff, Pere Gironella Gironell, J. S. Butter, M. Marinangeli, Michael Williams, Tatiana Gaintseva, Lorena Dieste Maronas, I. Williams, Anton Philippov, O. Schneider, Rudolf Oldeman, Roman Litvinov, Roel Aaij, Vadym Denysenko, Vasily Kudryavtsev, C. H. Murphy, Christopher Parkes, N. I. Voropaev, Jialu Wang, Felipe Luan Souza De Almeida, P. Spradlin, Francesca Dordei, A. Carbone, Jan Maratas, Jakub Jacek Malczewski, C. Gu, S. Bhasin, A. Camboni, O. Kot, Yipeng Sun, Iaroslava Bezshyiko, Ivan Shchemerov, Edoardo Franzoso, T. Ovsiannikova, Arnaud Robert, Thomas Latham, C. Patrignani, I. Carli, Julian Alexander Boelhauve, P. Collins, F. Pisani, F. Ferrari, K. R. Mattioli, V. Belavin, Murdo Traill, Alessandro Bertolin, D. Gerick, M. W. Slater, Sevda Esen, Ulrik Egede, L. Sun, Andrey Ustyuzhanin, T. Maltsev, Sajan Easo, Bernardo Adeva, Cibran Santamarina Rios, A. Dendek, Svende Braun, Diego Martinez Santos, Alessandro Petrolini, G. J. Kunde, S. Zhang, Danila Saranin, J. G. Smeaton, Marco Adinolfi, Adlène Hicheur, Benedict Donald C Westhenry, Stefania Ricciardi, Jifeng Hu, A. Merli, V. Tisserand, P. Gorbounov, T. Pajero, Karol Hennessy, Nikolay Nikitin, Marie Bachmayer, Alexandru Grecu, Thomas Ackernley, Marco Pappagallo, F. Redi, J. Hu, H. Li, K. Rinnert, Francesco Dettori, Adam Benjamin Morris, Jacopo Cerasoli, Gary Robertson, Sergey Gromov, Adam Davis, V. Pugatch, M. Hilton, Miguel Ramos Pernas, M. Féo, C. A. Aidala, Gaia Lanfranchi, Lex Marinus Greeven, Bhagyashree Pagare, Guy Wilkinson, Louis Henry, R. Calladine, Hilbrand Steffen Kuindersma, Marianna Fontana, C. M. Costa Sobral, D. Brundu, Niels Tuning, L. E. Yeomans, Luciano Pappalardo, D. Lancierini, M. Mulder, H. Cai, Paul Seyfert, C. Chen, Stefan Schael, Olivier Leroy, Yilong Wang, A. Venkateswaran, Arthur Marius Hennequin, Alessio Piucci, E. Santovetti, Yasmine Amhis, M. Atzeni, E. Grauges, Conor Fitzpatrick, Maxim Borisyak, Philippe d'Argent, X. Liang, Nuria Valls Canudas, A. Vorobyev, Dorothea Vom Bruch, Huanhuan Liu, Kristian Alexander Zarebski, Mariusz Witek, Mark Tobin, Michael Alexander, Renato Quagliani, Dmitrii Ilin, Q. Xu, Yongsheng Gao, Yanting Fan, Aleksei Andreianov, Harry Cliff, Wander Baldini, Victor Renaudin, Iain Longstaff, Anthony Gavin Downes, Julien Cogan, Bruno Souza De Paula, Jing Wang, Kenenbek Arzymatov, Adrian Casais Vidal, Dmitry Popov, G. Cavallero, Simon Akar, Matteo Giovannetti, V. Romanovskiy, Philippe Charpentier, Tomasz Fiutowski, Patrick Robbe, Robert Currie, Federico Alessio, Minh Tâm Tran, Christoph Frei, B. Quintana, Rainer Schwemmer, Pietro Marino, M. S. Rangel, Joel Closier, Matthew Birch, Kayleigh Anne Thomson, G. Panshin, Daniele Manuzzi, H. Malygina, J. L. Cobbledick, Abbie Jane Chadwick, B. Audurier, E. Maurice, T. Lesiak, F. Fleuret, I. Kostiuk, T. Mombächer, A. Bay, Sandra Amato, J. D. Roth, P. Campana, Victor Egorychev, Mikhail Shapkin, U. Uwer, Jinlin Fu, Jolanta Brodzicka, Biljana Mitreska, Alexey Dzyuba, K. Heijhoff, Y. Zhang, Yang Li, J. Qin, Gerwin Meier, Alex Pearce, Serena Maccolini, Jörg Marks, C. A. Chavez Barajas, Maria Vieites Diaz, Andrea Contu, A. Rollings, Xiaokang Zhou, Viacheslav Duk, Clara Remon Alepuz, Marcin Chrzaszcz, J. Plews, A. Ossowska, Liliana Congedo, Antonio Romero Vidal, Pascal Perret, G. Tuci, Abhijit Mathad, Z. Ren, A. Loi, Tomasz Skwarnicki, Sebastian Bachmann, Andrew George Morris, Polina Kravchenko, Thomas Ruf, A. Xu, M. Poliakova, Antonio Fernandez Prieto, Ivan Belyaev, Jan-Marc Basels, A. Artamonov, F. Reiss, Alexey Boldyrev, Artem Ryzhikov, Franz Muheim, G. H. Lovell, H. Dijkstra, M. Martinelli, Mark Richard James Williams, Flavio Fontanelli, Mikhail Zavertyaev, G. Raven, Alexander Bondar, Miroslaw Firlej, E. Shmanin, A. Kondybayeva, Juan Martin Otalora Goicochea, Laurent Dufour, V. Coco, Wouter Hulsbergen, Shuangli Yang, Zhihong Shen, Niladribihari Sahoo, Roger Forty, Frederic Machefert, Sheldon Stone, Domenico Galli, Lingzhu Bian, N. Serra, Darya Savrina, Paras Naik, Zoltan Mathe, Xiaoxue Han, Pablo Vazquez Regueiro, Nicola Neri, P. Ciambrone, Alison Tully, Michal Kreps, S. Poslavskii, G. Alkhazov, C. Meaux, Wojciech Wislicki, Mikhail Hushchyn, Sergey Strokov, Marco Guarise, V. Chobanova, C. Betancourt, Federico Lazzari, D. Murray, Marie Helene Schune, Q. Han, Paolo Carniti, E. Govorkova, M. Xu, Clara Matteuzzi, Quentin Fuehring, J. V. Mead, P. Mackowiak, Claire Prouve, Neville Harnew, Robbert Erik Geertsema, Eduard Ursov, Evelina Gersabeck, Barbara Passalacqua, Stefania Vecchi, Edward Brendan Shields, Angel Fernando Campoverde Quezada, Nicola Skidmore, Leonid Kravchuk, Maik Becker, Ettore Zaffaroni, Vasyl Dobishuk, Themistocles Bowcock, Gabriele Simi, Lukas Witola, Alberto Lusiani, A. Kharisova, Preema Rennee Pais, Biplab Dey, Lino Ferreira Lopes, Joan Ruiz Vidal, Miriam Lucio Martinez, N. Meinert, J. J. Walsh, Xuhao Yuan, D. Hynds, Francesco Polci, Michal Kazimierz Mazurek, M. Brodski, Z. Yang, Antonio Pellegrino, Kazuyoshi Carvalho Akiba, Matteo Rama, E. Dall'Occo, Sara Elizabeth Mitchell, Jan Langer, Eduardo Rodrigues, Michal Dziewiecki, Ana Barbara Rodrigues, Paula Garcia Moreno, Manuel Franco Sevilla, M. McCann, R. Kopecna, D. Gerstel, F. Keizer, A. Gomes, Federico Betti, P. Billoir, Yu Zhang, Maria Aranzazu Oyanguren, Sergio Gomez Fernandez, Jussara De Miranda, Phoebe Meredith Hamilton, G. Wormser, Vladimir Chulikov, Alexander Berezhnoy, Lakshan Ram Madhan Mohan, V. Obraztsov, Yue Pan, J. Heuel, J. Bhom, T. H. Hancock, V. Balagura, Denis Derkach, Erica Polycarpo, Rafael Silva Coutinho, Resmi Pk, M. Szymanski, Peter Griffith, Fergus Wilson, Elie Aslanides, Maciej Wojciech Dudek, Eric Thomas, S. Eisenhardt, Burkhard Schmidt, A. Chubykin, Adalberto Sciubba, Mitesh Patel, J. M. Durham, S. Nieswand, G. J. Pomery, Tatsuya Nakada, Olaf Steinkamp, G. Chatzikonstantinidis, Sergei Popov, C. D'Ambrosio, M. W. Majewski, M. Zeng, Yangheng Zheng, G. Bencivenni, M. S. Rudolph, Arnau Brossa Gonzalo, M. Schellenberg, Paula Alvarez Cartelle, T. Kirn, D. Wiedner, Sook Hyun Lee, Marco Clemencic, L. Martinazzoli, Daniel Charles Craik, Anatoliy Dovbnya, Artur Ishteev, Cameron Thomas Dean, M. Gersabeck, A. Vagner, F. Baryshnikov, Maria Flavia Cicala, K. Heinicke, D. Bobulska, Benjamin Couturier, Mateusz Goncerz, Alberto dos Reis, Milosz Zdybal, G. Pietrzyk, Stephen Farry, S. Escher, Michel De Cian, V. S. Kirsebom, Silvia Ferreres Sole, Antonios Papanestis, Alessandro Cardini, Maarten Van Dijk, Jibo He, H. M. Wark, Paul Nathaniel Swallow, Silvia Gambetta, Timothy Gershon, Youen Kang, S. Blusk, Daniel Vieira, Saverio Mariani, Vukan Jevtic, Tara Shears, Vitaly Vorobyev, Basem Khanji, D. Marangotto, Thomas Blake, Chishuai Wang, Marek Idzik, Lars Eklund, M. Materok, Anton Poluektov, Lorenzo Sestini, Achim Vollhardt, M. G. Chapman, Rafel Manera Escalero, Leon David Carus, Ziad Ajaltouni, Dominik Stefan Mitzel, Barbara Sciascia, Liliet Calero Diaz, Guillermo Loustau, Thomas Hadavizadeh, Raymond Mountain, Markus Frank, Donal Hill, Scott Ely, Beatriz Garcia Plana, Gianluca Zunica, Alexander Leflat, Chung Nguyen-Mau, Karlis Dreimanis, Sophie Elizabeth Hollitt, Raja Nandakumar, Claudio Gotti, S. Aiola, Oscar Boente Garcia, Sebastian Neubert, Hossein Afsharnia, Dominik Müller, Daniel Lacarrere, Julian Lomba Castro, P. E. L. Clarke, David Websdale, Giulia Frau, Lishuang Ma, F. Archilli, Alexander Semennikov, W. Hu, Thomas Grammatico, S. Koliiev, Peter Svihra, S. Simone, Gregory Ciezarek, M. Veronesi, E. Gabriel, J. Sun, A. Beiter, Olivier Deschamps, Lei Li, Laura Promberger, Luis Alberto Granado Cardoso, Cynthia Nunez, Vinicius Franco Lima, Sergei Kholodenko, A. Konoplyannikov, Giuseppe Martellotti, B. Malecki, Wojciech Krzemien, Alessio Sarti, Thierry Gys, Alexandre Brea Rodriguez, Jeremy Dalseno, Oleksandr Zenaiev, Eleonora Luppi, Albert Bursche, L. Douglas, Donatella Lucchesi, Marilisa De Serio, Liupan An, M. E. Stramaglia, S. Maddrell-Mander, Petr Fedin, B. Batsukh, M. Bjørn, Carla Göbel, S. Cali, Sneha Malde, William Barter, Andrey Golutvin, F. Blanc, Jaap Velthuis, I. V. Gorelov, Giovanni Bassi, Lucas Meyer Garcia, T. Harrison, Yu Lu, K. Wyllie, Mikhail Mikhasenko, Andrea Bizzeti, Youhua Yang, Vincenzo Vagnoni, Giovanni Carboni, Mauro Piccini, A. Valassi, Piera Muzzetto, Luke George Scantlebury Smead, Jonas Nathanael Eschle, Guido Haefeli, Z. Xiang, Zhenzi Wang, Xabier Cid Vidal, Dylan Jaide White, Michela Garau, Marko Milovanovic, Christopher Jones, Naylya Sagidova, A. Alfonso Albero, B. Rachwal, Claudia Bertella, E. Ben-Haim, M. P. Blago, Kamil Leszek Fischer, Aleksandra Snoch, M. Wang, Paolo Durante, Maitreyee Mukherjee, Luis Miguel Garcia Martin, Ignacio Bediaga, Desmond Mzamo Shangase, Kyung Eun Kim, Martino Borsato, Lev Shekhtman, Carina Trippl, Lucia Grillo, Aleksandr Solovev, Xuesong Liu, Tabitha Halewood-leagas, J. P. Grabowski, Jingzhou Fan, H. Mu, Nikolay Bondar, Roland Bernet, Paul Soler, Marcel Merk, Massimiliano Ferro-Luzzi, Fidan Suljik, Sara Celani, Leandro De Paula, Tjeerd Ketel, Niko Neufeld, V. Placinta, Juan Mauricio, N. V. Raab, Emilie Bertholet, S. Petrucci, S. Zucchelli, Evangelos Leonidas Gkougkousis, Y. Yao, Zhihao Xu, Tengiz Kvaratskheliya, Cristina Sanchez Gras, Daniel Johnson, A. Gioventù, Tamaki Holly Mcgrath, D. Melnychuk, P. Kopciewicz, K. Petridis, Beat Jost, Marco Cattaneo, Agnieszka Oblakowska-Mucha, F. Kress, Stefan-Gabriel Chitic, Joseph David Shupperd, Felipe Andres Garcia Rosales, André Massafferri, A. Mauri, Oleg Maev, Luigi Del Buono, L. Xu, Martina Ferrillo, Matthew Needham, Carlos Vázquez Sierra, Giovanni Punzi, R. Newcombe, A. Battig, L. Shchutska, Eluned Smith, D. Pereima, A. Mödden, Ronan McNulty, Shantam Taneja, Matthew Kenzie, Zehua Xu, Daria Strekalina, Fionn Caitlin Ros Bishop, Juan Baptista Leite, K. Prasanth, Juan Jose Saborido Silva, Celestina Satriano, A. Seuthe, Thi Dung Nguyen, Krzysztof Swientek, Matthew James Tilley, Xavier Vilasis-Cardona, Nathanael Farley, F. Jiang, Tai-Hua Lin, Marina Artuso, Olga Madejczyk, D. Maisuzenko, Simone Capelli, Y. Luo, Ouail Kitouni, Johannes Albrecht, Malcolm John, Brian Meadows, Sophie Baker, F. Bedeschi, Roberta Cardinale, Roberta Santacesaria, Charlotte Barbara Van Hulse, I. Polyakov, Matthias Karacson, Xiaotao Huang, Elisabetta Spadaro Norella, Mark Wilkinson, Roland Waldi, B. G. Siddi, Oleg Yushchenko, Heinrich Schindler, Matthew Charles, Maksim Karpov, M. J. Bradley, Nathan Jurik, Zishuo Yang, Jianqiao Wang, Julián García Pardiñas, Biagio Saitta, H. Yin, Stanislav Luchuk, Mihai Straticiuc, S. Didenko, Gerco Onderwater, Christoph Langenbruch, Gianluigi Casse, D. Dutta, K. Ivshin, Daniel Joachim Unverzagt, W. Byczynski, Sara Sellam, Diego Alejandro Milanes, M. Andreotti, Sergey Barsuk, Ruiting Ma, T. Colombo, Oliver Lantwin, K. Gizdov, A. Sergi, G. Sarpis, Richard Lane, William Dean, Serhii Cholak, Andrew McNab, Pasquale Di Nezza, Giovanni Valenti, Davide Pinci, Patrick Owen, Michael Joseph Morello, Giampiero Mancinelli, M. Hecker, Vladimir Gligorov, M. Pili, Mauro Morandin, S. Belin, Philippe Ghez, W. Funk, Guanghua Gong, Hangyi Wu, Christopher John Parkinson, Lluis Garrido, Jennifer Clare Smallwood, Anatoly Butkevich, Minaugas Sarpis, Fernando Martinez Vidal, David Sanchez Gonzalo, Patricia Camargo Magalhaes, Michele Veltri, Alessia Satta, Sai-Juan Chen, Fedor Ratnikov, Marcin Kucharczyk, Florin Maciuc, Marco Petruzzo, Jacco de Vries, Maximilien Chefdeville, Luca Tomassetti, Marian Stahl, Jana Crkovská, A. Buonaura, F. Desse, Philip Ilten, Gloria Corti, V. Bellee, Rolf Lindner, Y. Gan, Stefano Perazzini, H.-P. Dembinski, Ivan Solovyev, Blake Leverington, D. Y. Tou, Fernanda Goncalves Abrantes, B. K. Jashal, V. Lisovskyi, Christophe Haen, Martinus van Beuzekom, E. Millard, Pascal Vincent, Lorenzo Capriotti, Nikita Kazeev, Jingyi Xu, Steffen Georg Weber, Rizwaan Adeeb Mohammed, A. Jawahery, Diego Torres Machado, H. Pullen, Renaud Le Gac, Jie Yu, Matteo Palutan, A. Pastore, Thomas Boettcher, M. Bartolini, R. A. Fini, Roberto Ribatti, A. Ene, Lorenzo Pica, A. Palano, Tomasz Szumlak, D. Berninghoff, Y. Zhou, M. Schubiger, Rafal Dominik Krawczyk, David Hutchcroft, R. I. Rabadan Trejo, Eva Vilella Figueras, M. Reboud, M. Saur, Igor Skiba, and Wenbin Qian
Subjects: Physics, Quantum chromodynamics, Particle physics, Multidisciplinary, Strangeness, 010502 geochemistry & geophysics, Quarkonium, Lambda, 01 natural sciences, Pentaquark, Luminosity, Excited state, High Energy Physics::Experiment, Invariant mass, 0105 earth and related environmental sciences
Abstract: First evidence of a structure in the $J/\psi{\Lambda}$ invariant mass distribution is obtained from an amplitude analysis of$\Xi_b^-{\rightarrow}J/\psi{\Lambda}K^-$ decays. The observed structure is consistent with being due to a charmonium pentaquark with strangeness with a significance of $3.1\sigma$ including systematic uncertainties and look-elsewhere effect. Its mass and width are determined to be $4458.8\pm2.9^{+4.7}_{-1.1}$ MeV and $17.3\pm6.5^{+8.0}_{-5.7}$ MeV, respectively, where the quoted uncertainties are statistical and systematic. The structure is also consistent with being due to two resonances. In addition, the narrow excited $\Xi^-$ states, $\Xi(1690)^-$ and $\Xi(1820)^-$, are seen for the first time in a $\Xi^-_b$ decay, and their masses and widths are measured with improved precision. The analysis is performed using $pp$ collision data corresponding to a total integrated luminosity of 9 fb$^{-1}$, collected with the LHCb experiment at centre-of-mass energies of 7, 8 and 13 TeV.
Published: 2021

34. Pregnancy-induced changes in ocular biomechanics are maternal hormone- related in healthy Chinese pregnant women

Author: Fangyuan Chen, Jianting Zhou, Xiaojuan He, Xiaoxue Han, Rijia Zhang, and Qing Zhou
Abstract: BackgroundTo explore the changes of ocular biomechanics during pregnancy and the postpartum period and its association with maternal hormone changes. Methods Prospective cohort study. Pregnant women (n = 12,24 eyes) were enrolled in this study, and monitored throughout pregnancy and after delivery (7 days). After routine ophthalmologic examination, intraocular pressure (IOP), central corneal thickness (CCT), corneal endothelium cell (CEC), axial length (AL), corneal curvature (K1, K2), anterior chamber depth (ACD), central subfield thickness (CST), macular volume (MV), cube average thickness (CAT), retinal nerve fiber layer (RNFL), tear meniscus height (TMH), and breaking up time (BUT) were measured, and blood plasma levels of the maternal hormone were determined at the same. ResultsA gradual decrease in IOP value as the gestational week progressed, there was a statistically significant difference between the 3rd trimesters and 1st trimesters, 2nd trimesters and postpartum (p=0.002, p=0.006, and p= 0.050, respectively). There was a statistical difference between the first trimesters and the second trimesters in terms of MV (p=0.023). The difference in RNFL in the 3rd trimesters and postpartum was significant (p=0.011). Assessment of other ophthalmic parameters revealed no statistically significant changes (p>0.05, repeated measures ANOVA). There only was a significant correlation between K2, ACD, and TMH in the second trimester (r=0.588, p=0.045; r=-0.740, p=0.006; r=0.642, p=0.024, respectively). Regarding luteinizing hormone, there was a significant difference between with MV (r=-0.598, p =0.040 in the first trimester; r=-0.672, p =0.040, p = 0.017); and CAT (r=-0.598, p =0.040 in the 1st trimester; r=-0.672, p =0.040 in the 2nd trimester);ACD(r=-0.702,p=0.011 in the 2nd trimester) and K2 (r=0.585,p=0.046 in the 3rd trimester).A negative correlation was found between the follicle-stimulating hormone and CEC, MV and CAT in the first trimester (r=-0.677, p=0.016; r=-0.602, p =0.039; r=-0.584, p=0.046; respectively) and AL in the third trimester (r=-0.618, p=0.032). The correlation between estradiol and ocular parameters appeared with CST in the first trimester (r=-0.621, p =0.031), and RNFL (r=0.594, p=0.041) postpartum; and a statistically correlation between progesterone and MV (r=0.583, p=0.047) and TMH (r=0.762, p=0.004) in the first trimester. No significant intergroup correlation was observed in postpartum (all p > 0.05).ConclusionWe found that ophthalmic parameters had physiological changes induced by hormones in pregnancy and returned to baseline levels after delivery.
Published: 2022

35. Regulating electronic environment on alkali metal-doped Cu@NS-SiO2 for selective anisole hydrodeoxygenation

Author: Xiaofei Wang, Xiaoxue Han, Li Kang, Shixiang Feng, Meiyan Wang, Yue Wang, Shouying Huang, Yujun Zhao, Shengping Wang, and Xinbin Ma
Subjects: General Medicine
Published: 2022

36. Tunable Fe3O4 nanoparticles assembled porous microspheres as catalysts for Fischer-Tropsch synthesis to lower olefins

Author: Shouying Huang, Xiaoxue Han, Haoting Liang, Qiao Zhao, Xinbin Ma, Jian Wang, Yue Wang, and Hongyu Wang
Subjects: Materials science, Nanostructure, Nanoparticle, Fischer–Tropsch process, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Catalysis, 0104 chemical sciences, Adsorption, Chemical engineering, Phase (matter), Particle size, 0210 nano-technology, Selectivity
Abstract: Fe catalyzed Fischer-Tropsch synthesis to lower olefins (FTO) has been recognized as a structure-sensitive reaction. Nanostructure Fe-based catalysts can expose more active surface. But bulk nanostructure Fe catalysts without support interaction show easily sintered and agglomerated, which makes hard to investigate size effect. Therefore, the effect of particle size on bulk Fe catalysts have rarely been reported. Herein, nanoparticles assembled Fe3O4 bulk catalysts were synthesized via a PAA-mediated solvothermal method to solely investigate the size effect of Fe phase. By tuning preparation parameters, a series of porous-Fe3O4 microspheres assembled by different nanoparticle size (8.5–16.5 nm) was obtained, maintaining constant microspheres size. When Fe3O4 nanoparticles are smaller than 10 nm, catalysts show similar catalytic activity (FTY). Beyond 10 nm, the FTY obviously decreases with increasing of particle size. Particularly, Fe3O4 with nanoparticle size of 9.9 nm performs the highest activity as well as C2-C4= selectivity and O/P ratio. The smaller particles attribute to C5+ formation, while inhibit CH4 selectivity. By CO-TPD, TPH-MS and XRD analysis, we discuss size effect on CO adsorption, surface carbon species and carburization degree, building relationship between particle size and catalytic activity. It is found that the carburization degree of iron phase correlates positively with catalytic activity. These results deepen understanding of the structure-performance relationship for bulk iron catalysts in FTO.
Published: 2021

37. Highly active and controllable MOF-derived carbon nanosheets supported iron catalysts for Fischer-Tropsch synthesis

Author: Jing Lv, Xiaoxue Han, Shouying Huang, Qiao Zhao, Junhu Wang, Mei-Yan Wang, Yue Wang, Alexandre I. Rykov, Jiajia Chen, and Xinbin Ma
Subjects: Materials science, Dopant, chemistry.chemical_element, Fischer–Tropsch process, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Catalysis, symbols.namesake, chemistry, Chemical engineering, X-ray photoelectron spectroscopy, symbols, General Materials Science, 0210 nano-technology, Raman spectroscopy, Pyrolysis, Carbon, Monoclinic crystal system
Abstract: N-doped carbon materials as catalyst supports have shown great superiority because of rich porosity, tunable metal-support interaction and electronic promotion effect. Controllable fabrication of carbon materials with specific morphology and different configurations provides wider possibilities for applications in catalysis. Herein, N-doped carbon nanosheets (CNS) were successfully synthesized by using monoclinic ZIF-8 nanosheets as templates. Compared with commercial active carbon and cubic ZIF-8 particles-derived carbon particles, the derived CNS exhibit superior graphitization degree and electronic effect. Consequently, the promoted Fe carburization improved the intrinsic activity for Fe/CNS catalysts in FTS. Further investigation on pyrolysis temperature achieved tunable configuration and content of N dopant. XPS, Raman, Mossbauer spectroscopy, TEM, H2-TPR etc. were combined to elucidate the promotion effect of CNS on dispersion, electronic properties and formation of Fe carbides. By correlating the composition and structure to catalytic performance in FTS, we illustrated the significance of carbon materials in Fe supported catalysts.
Published: 2021

38. Cooperative advertising strategy selection problem for considering pricing and advertising decisions in a two-period online supply chain

Author: Bo Xie, Weizi Li, Peiyan Jiang, Xiaoxue Han, and Lei Qi
Subjects: Article Subject, General Mathematics, General Engineering
Abstract: This article studies the cooperative advertising problem of a two-period online supply chain consisting of a manufacturer and an online retail platform. The manufacturer provides national advertising in the first period to build the brand image and increase the awareness of the product. And the online retail platform provides platform advertising for selling the product to consumers on its platform during two periods. The manufacturer and the online retail platform may choose different cooperative advertising strategies for national advertising and platform advertising, which are one-way subsidy strategy, two-way subsidy strategy, and revenue-share strategy. We formulate a Stackelberg game model to study the cooperative advertising problem by taking price and advertising effect into account and analyze how the profit is influenced in different cooperative advertising strategies. We find that under the revenue-share strategy, the manufacturer provides a higher subsidy rate for the online retail platform advertising than that in other cooperative advertising strategies. Interestingly, there are conditions where, while just the manufacturer contributes a percentage of the platform advertising and the online retail platform has no effort on the national advertising, the total profit would be better than that in revenue-share strategy even in revenue-share strategy, the cooperative relationship is closer between the manufacture and the online retail platform.
Published: 2022

39. THE BOUNDS OF EIGENVALUE FOR COMPLEX SINGULAR BOUNDARY VALUE PROBLEMS.

Author: FU SUN and XIAOXUE HAN
Subjects: EIGENVALUES, MATHEMATICAL bounds, BOUNDARY value problems, MATHEMATICAL singularities, LEGENDRE'S functions, PERTURBATION theory
Abstract: The present paper deals with "the perturbation of Legendre eigenvalue problem" with limit-circle type non-oscillation endpoints. The dissipative operators in limit-circle case are studied. Lower bounds on the real parts of all eigenvalues and the upper bounds on the imaginary parts of the non-real eigenvalues for this eigenvalue problem associated to a special separated boundary condition (see the below in (3.1b)) are obtained through a new method, partly inspired by the estimates obtained in Sun and Qi (Proc. Roy. Soc. Edinburgh A, 150:2607-2619, 2020). [ABSTRACT FROM AUTHOR]
Published: 2023
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40. Knowledge and Attitude of the Medical Staff Concerning Cardiac Rehabilitation in Zhejiang Province, China: A Cross-Sectional Study

Author: Xiaoxue Han, Zhihong Ye, Yuan Wu, Haixiang Zhu, and Li Ning
Subjects: medicine.medical_specialty, Medical staff, Rehabilitation, business.industry, Cross-sectional study, Health Policy, medicine.medical_treatment, 05 social sciences, Specialty, Medicine (miscellaneous), Questionnaire, Subgroup analysis, Work experience, 0506 political science, 03 medical and health sciences, 0302 clinical medicine, Family medicine, 050602 political science & public administration, medicine, 030212 general & internal medicine, business, China, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Social Sciences (miscellaneous)
Abstract: Purpose This study aimed to investigate the status of cardiac rehabilitation knowledge and attitude of the medical staff. Patients and Methods A questionnaire survey of doctors and nurses was performed in the departments of cardiology of 7 teaching hospitals with attitudes, knowledge toward CR in Zhejiang Province, China, from April to September 2018, to assess Chinese medical staff for the degree of mastery and attitude toward cardiac rehabilitation. Results A total of 160 questionnaires were distributed and 152 valid were collected. The responding individuals included 106 nurses (69.74%) and 46 doctors (30.26%). The scores of cardiac rehabilitation knowledge were 56.68±5.06, and those of cardiac rehabilitation attitude were 15.19±3.86. Subgroup analysis showed the lower the job title (P
Published: 2020

41. Comparison of Clinical Results and Quality-of-Life in Tongue Cancer Patients Undergoing Submental Island Flap and Radial Forearm Free Flap Reconstruction

Author: Yujing Wang, Xiaoxue Han, Jun Zhang, and Huiqiao Chen
Subjects: medicine.medical_specialty, Tongue squamous cell carcinoma, Free Tissue Flaps, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Tongue, medicine, Humans, In patient, Survival analysis, business.industry, Cancer, 030206 dentistry, Plastic Surgery Procedures, medicine.disease, Tongue Neoplasms, Surgery, Forearm, medicine.anatomical_structure, Otorhinolaryngology, Radial forearm free flap, 030220 oncology & carcinogenesis, Quality of Life, Neoplasm Recurrence, Local, Oral Surgery, business, American society of anesthesiologists
Abstract: Purpose Our goal was to compare the clinical results and quality-of-life (QoL) in tongue cancer patients undergoing submental island pedicled (SIP) flap and radial forearm free (RFF) flap reconstruction. Materials and Methods Patients undergoing SIP or RFF flap reconstruction for primary tongue squamous cell carcinoma were prospectively enrolled and were asked to complete the University of Washington Quality-of-Life (UW-QOL) questionnaire, version 4, at 12 months after the operation. The study's main interest was QoL as well as locoregional recurrence control. Results A total of 190 patients were enrolled for analysis, and the SIP and RFF groups showed significant differences in patient age, American Society of Anesthesiologists classification, and hospital cost. In the survival analysis, locoregional recurrence occurred in 35 patients in the SIP group and 48 patients in the RFF group; the difference was not significant (P = .440). In the QoL analysis, compared with patients in the SIP group, those in the RFF group had higher scores in the domains of activity and recreation. No significant differences were found with respect to the other domains. Conclusions The SIP flap and RFF flap have comparable survival control in tongue squamous cell carcinoma patients. The RFF flap might lead to better QoL, but the SIP flap imposes fewer limitations on patients' health status and is associated with lower hospital cost.
Published: 2020

42. Oxygen therapy alleviates hepatic steatosis by inhibiting hypoxia-inducible factor-2α

Author: Jinhui Wu, Xiaoxue Han, Dalong Zhu, Haoran Wang, Wenhuan Feng, Lei Yu, Honghui Liu, and Yan Bi
Subjects: 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Mice, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Overnutrition, Non-alcoholic Fatty Liver Disease, Internal medicine, Basic Helix-Loop-Helix Transcription Factors, Animals, Medicine, Hypoxia, Cells, Cultured, medicine.diagnostic_test, business.industry, Lipogenesis, Fatty liver, Hypoxia (medical), Lipid Metabolism, medicine.disease, Oxygen, 030104 developmental biology, Liver, Hypoxia-inducible factors, Liver biopsy, Hepatocytes, medicine.symptom, Signal transduction, Steatosis, business, Signal Transduction
Abstract: Non-alcoholic fatty liver disease (NAFLD) is difficult to manage due to the lack of effective treatments. Increased oxygen consumption caused by overnutrition, along with reduced oxygen delivery to liver cells induces hepatic steatosis. Here, we investigated the efficacy of oxygen therapy (OT) to alleviate hepatic steatosis. The effect of OT on hepatic steatosis was evaluated in high-fat-diet (HFD)-fed mice and palmitic acid (PA)-treated primary hepatocytes. Liver biopsy tissue samples were used to determine the relationship between the expression of hypoxia-inducible factor-2α (HIF-2α) and the progression of NAFLD. The role of HIF-2α in the OT group was determined based on the overexpression of HIF-2α in vitro. OT safely alleviated hepatic hypoxia and improved hepatic steatosis by inhibiting hepatic de novo lipogenesis in HFD-fed mice and PA-treated primary hepatocytes, and this was accompanied by reduced expression of HIF-2α and hepatic de novo lipogenesis. The analysis of liver tissues from individuals with or without NAFLD revealed a positive correlation between hepatic HIF-2α expression and NAFLD progression. Overexpression of HIF-2α in vitro inhibited the beneficial effect of OT against hepatic lipogenesis and steatosis. OT might be a viable treatment option for NAFLD and functions by alleviating hypoxia and inhibiting the liver HIF-2α signaling pathway.
Published: 2020

43. Capture of Toxic Gases by Deep Eutectic Solvents

Author: Wangxin Guo, Zhenghui Liu, Tiancheng Mu, Dongkun Yu, Yu Chen, and Xiaoxue Han
Subjects: Renewable Energy, Sustainability and the Environment, General Chemical Engineering, Hydrogen sulfide, Air pollution, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, medicine.disease_cause, 01 natural sciences, 0104 chemical sciences, Nitric oxide, Ammonia, chemistry.chemical_compound, chemistry, Environmental chemistry, medicine, Environmental Chemistry, Nitrogen dioxide, Acid rain, 0210 nano-technology, Sulfur dioxide, Eutectic system
Abstract: Sulfur dioxide (SO2), ammonia (NH3), hydrogen sulfide (H2S), nitrogen dioxide (NO2), and nitric oxide (NO) are toxic gases from industrial exhaust, which could lead to acid rain, air pollution, hea...
Published: 2020

44. Mixed 2- and 2r-level fractional factorial split-plot designs with clear effects

Author: Xiaoxue Han, Min-Qian Liu, Jian-Feng Yang, and Shengli Zhao
Subjects: Statistics and Probability, Applied Mathematics, Statistics, Probability and Uncertainty
Published: 2020

45. Activating nitrogen-doped carbon nanosheets by KOH treatment to promote the Fischer-Tropsch synthesis performance

Author: Qiao Zhao, Xiaoxue Han, Haoting Liang, Yue Wang, Jing Lv, Mei-Yan Wang, Shouying Huang, and Xinbin Ma
Subjects: General Chemical Engineering, Environmental Chemistry, General Chemistry, Industrial and Manufacturing Engineering
Published: 2023

46. Asymmetrical split-plot designs with clear effects

Author: Xiaoxue Han, Min-Qian Liu, Jianbin Chen, and Shengli Zhao
Subjects: Statistics and Probability, Discrete mathematics, Split plot, Mixed level, Fractional factorial design, Main effect, Statistics, Probability and Uncertainty, Prime power, Prime (order theory), Resolution (algebra), Mathematics
Abstract: The fractional factorial split-plot (FFSP) design is an important experimental design both in theory and in practice. There is extensive literature on the two-level FFSP design and its various variants. However, there is little work on the s-level FFSP design and its variants in the asymmetrical (i.e., mixed-level) case, where s is any prime or prime power. Such designs are commonly used e.g. in agriculture, medicine and chemistry. This paper provides the necessary and sufficient conditions for the existence of resolution III or IV regular $$s^{(n_1+n_2)-(k_1+k_2)}(s^r)$$ designs which contain clear main effects or two-factor interaction components. In particular, the sufficient conditions are proved through constructing the corresponding designs, and some examples are provided to illustrate the construction methods.
Published: 2019

47. High-Pressure Phase Transitions in Densely Packed Nanocrystallites of TiO2-II

Author: Xiaoliang Zhang, Kuo Li, Bingmin Yan, Weiwei Li, Martin Kunz, Junxiu Liu, Dongzhou Zhang, Hengzhong Zhang, Xiaoxue Han, Huiyang Gou, Hui Jiang, Jian Chen, Hua Tian, Zhen Chen, and Weixin Liu
Subjects: Phase transition, Work (thermodynamics), General Energy, Materials science, High pressure, Phase (matter), Analytical chemistry, Physical and Theoretical Chemistry, Nanocrystalline material, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Ambient pressure
Abstract: Phase behaviors of nanocrystalline TiO2-II have not been well studied due to the difficulty in its preparations at ambient pressure. In this work, we prepared nanocrystallites of TiO2-II with avera...
Published: 2019

48. Observation of excited Ωc0 baryons in Ωb−→Ξc+K−π− decays

Author: Matteo Rama, Harris Conan Bernstein, C. Bozzi, Sara Elizabeth Mitchell, Monica Pepe Altarelli, Mika Vesterinen, Veronika Chobanova, Jan Langer, Aleksandr Petrov, Xiaoxue Han, Stephane T'Jampens, Giacomo Graziani, Ross John Hunter, Pablo Vazquez Regueiro, Vlad-Mihai Placinta, Erica Polycarpo, Jennifer Brigitta Zonneveld, Dmitry Golubkov, Kevin Heijhoff, Lorenzo Capriotti, Samuel Belin, Stefania Ricciardi, Constantin Weisser, Dmytro Melnychuk, Agnieszka Dziurda, Stephen Farry, Marta Calvi, Miroslav Saur, Antonios Papanestis, Paul Nathaniel Swallow, Yuezhe Yao, Halime Sazak, Maarten van Veghel, G. Alkhazov, Michael McCann, Alexandre Boyer, Charlotte Barbara Van Hulse, Elisabetta Spadaro Norella, Jose Lopes, Giulia Manca, Mengzhen Wang, Giovanni Punzi, Artem Maevskiy, Wojciech Wislicki, Mikhail Hushchyn, Ekaterina Trifonova, Thierry Gys, Alexandre Brea Rodriguez, Oleg Yushchenko, Thomas Peter Jones, A. Jawahery, Diego Torres Machado, Renaud Le Gac, Andrea Lampis, Xuhao Yuan, Jiayin Sun, Davide Zuliani, Jike Wang, Patrick Mackowiak, Thomas Boettcher, Ryan Newcombe, Ilia Belov, Evgenii Shmanin, Matthew Birch, Heinrich Schindler, Silvia Borghi, Pavel Krokovny, Qundong Han, Sophie Katharina Kretzschmar, Guoming Liu, Boleslaw Pietrzyk, Mario Edgardo Olivares, Rui Wang, Svende Braun, Bo Fang, Eddy Jans, Sergey Filippov, Maciej Wojciech Dudek, Michele Veronesi, Zakariya Aliouche, Andreas Schopper, Camille Normand, Wojciech Kucewicz, Yiduo Shang, Maksim Karpov, Igor Kostiuk, Anna Lupato, Razvan Daniel Moise, Antonio Fernandez Prieto, Jiesheng Yu, Miriam Gandelman, Ivan Belyaev, Mariia Poliakova, Sergii Kandybei, Roger Barlow, Martin Stefan Bieker, Daniel Charles Craik, Jan-Marc Basels, Konstantin Gizdov, Wiktor Byczynski, Federico Redi, George Lafferty, Quan Zou, George Coombs, Alastair Roger Tanner, Hui Li, Federico Alessio, Minh Tâm Tran, Anatoliy Dovbnya, Fabio Ferrari, George Holger Lovell, Silvia Ferreres Sole, Maria Vieites Diaz, Andrea Contu, Marco Poli Lener, A. Artamonov, Hongrong Qi, Michal Kazimierz Mazurek, Antonio Falabella, Carmen Giugliano, Manuel Schiller, Lauren Douglas, Marcos Romero Lamas, Stephane Monteil, Francesco Dettori, Tatiana Gaintseva, Pierre Billoir, Titus Mombächer, Thomas Grammatico, Yangheng Zheng, Carmelo D'Ambrosio, Jean François Marchand, Oleg Stenyakin, Roman Litvinov, Aleksandr Terentev, Jonas Rademacker, Marco Santimaria, Mark Hatch, Roberto Calabrese, Louis Lenard Gerken, Mirco Andreotti, Yu Zhang, Xiaokang Zhou, Stephan Escher, Adriano Lai, Tatiana Ovsiannikova, Arthur Marius Hennequin, Jan Maratas, Marek Jezabek, Michael Brodski, Heather Mckenzie Wark, Patrick Koppenburg, Lei Zhang, Sandro Cadeddu, Yipeng Sun, Gerd Joachim Kunde, C. M. Costa Sobral, Jozef Tomasz Borsuk, Johannes Heuel, Yu Lu, Sebastian Schulte, Huanhuan Liu, Nikolay Bondar, Niko Neufeld, Marianna Fontana, Tomasz Skwarnicki, Roberto Ribatti, Stephen M. Stahl, Wojciech Krupa, Oleksander Kot, Alison Tully, Dorothea Vom Bruch, Viacheslav Duk, Zishuo Yang, Alessandro Petrolini, Sergey Legotin, Juan Mauricio, Renato Quagliani, Florin Maciuc, Brij Kishor Jashal, Lorenzo Pica, Marco Petruzzo, Marian Stahl, Yasmine Amhis, Gabriela Johanna Pomery, Matteo Giovannetti, Alexey Boldyrev, John Matthew Durham, Julián García Pardiñas, Naomi Veronika Raab, Jianqiao Wang, Igor Slazyk, Alexandru Grecu, Thomas Ackernley, Niladribihari Sahoo, Eric Cogneras, Alexander Malinin, Biagio Saitta, Stanislav Luchuk, Tengiz Kvaratskheliya, Clara Remon Alepuz, Angel Fernando Campoverde Quezada, Mihai Straticiuc, Eliane Epple, Wenqian Huang, Cibran Santamarina Rios, Efren Rodriguez Rodriguez, Serhii Koliiev, A. Palano, Tomasz Szumlak, Simon Nieswand, Eric van Herwijnen, Dongliang Zhang, Annarita Buonaura, Valery Zhukov, Chen Chen, Anton Philippov, Nicola Serra, Stephanie Hansmann-Menzemer, Zirui Wang, Sofia Kotriakhova, Jihyun Bhom, Kazuyoshi Carvalho Akiba, Yutong Li, Sebastian Bachmann, Andrew George Morris, Sneha Malde, Konstantinos Petridis, Lucas Meyer Garcia, Abbie Jane Chadwick, Flavio Pisani, Antje Mödden, Yang Gao, U. Uwer, Kenneth Wyllie, Davide Fazzini, Cheryl Pappenheimer, Lais Soares Lavra, Marcin Chrzaszcz, Carla Göbel, Michael Alexander, Liliana Congedo, Antonio Romero Vidal, Thomas Henry Hancock, Vladimir Macko, Yury Guz, Regis Lefèvre, Valerie Gibson, Patrizia De Simone, Shuaiyi Liu, Marie-Noelle Minard, Clara Gaspar, Davide Lancierini, Lavinia-Helena Giubega, Rafal Dominik Krawczyk, Daniel Patrick O'Hanlon, Ricardo Vazquez Gomez, David Anthony Friday, Lorena Dieste Maronas, Dana Bobulska, Alessandro Bertolin, Lakshan Ram Madhan Mohan, Yue Pan, Peter Griffith, Elie Aslanides, Alexandra Paige Rollings, John Leslie Cobbledick, T. Lesiak, Alexander Inglessi, Thomas Ruf, Da Yu Tou, Rolf Lindner, Stefano Perazzini, Martino Borsato, Claudia Bertella, Marilisa De Serio, V. Obraztsov, Christopher Betancourt, Andrea Merli, Ekaterina Govorkova, Gerco Onderwater, Stephan Eisenhardt, Dario de Simone, Juan Baptista Leite, Michael Schmelling, Stefano Cali, Suzanne Klaver, William Barter, Martina Pili, Angelo Carbone, Bartlomiej Rachwal, Jaap Velthuis, Luke George Scantlebury Smead, Guido Haefeli, Ivan Solovyev, Vasily Kudryavtsev, Hang Yin, Jacopo Cerasoli, Dmitrii Maisuzenko, Hans Dijkstra, Maxim Borisyak, Lucian Cojocariu, Sevda Esen, Ulrik Egede, Piera Muzzetto, Diego Martinez Santos, Alex Seuthe, Wolfgang Funk, Rafael Silva Coutinho, Resmi Pk, Ivan Polyakov, David Hutchcroft, Matthew George Chapman, Marko Milovanovic, Emilie Maurice, Marko Petrič, A. Gomes, Federico Betti, Maria Aranzazu Oyanguren, Paul Andre Günther, Jing Wang, Shakhzod Dadabaev, Tabitha Halewood-leagas, Alexander Vagner, Anna Danilina, Artur Ukleja, Mark Wilkinson, Roland Waldi, Timofei Maltsev, O. Schneider, Thomas Kirn, Rosen Matev, Mark E. Smith, Katharina Müller, Fernanda Goncalves Abrantes, Tara Shears, B.R. Gruberg Cazon, Vitaly Vorobyev, Zan Ren, Alex Daniel Fernez, Matthew Charles, Feng Jiang, Matthieu Marinangeli, Christine Angela Aidala, Dirk Wiedner, Maria Flavia Cicala, R. I. Rabadan Trejo, Eva Vilella Figueras, Ievgenii Petrenko, Christopher Parkes, Stefan Schael, Olivier Leroy, Mark Richard James Williams, Flavio Fontanelli, Mikhail Zavertyaev, Iaroslava Bezshyiko, Jose Maria Fernandez-tenllado Arribas, Aleksei Chernov, Ivan Shchemerov, Florian Reiss, Jonas Nathanael Eschle, Natalia Polukhina, Karol Hennessy, Wenhua Hu, Julian Alexander Boelhauve, Youen Kang, Marcel Merk, Daniel Decamp, Jairo Alexis Rodriguez Lopez, Ouail Kitouni, S. Blusk, Alex Pearce, Edoardo Franzoso, Anton Poluektov, Lorenzo Sestini, Polina Kravchenko, Lucio Anderlini, Fidan Suljik, Sara Celani, Sune Jakobsen, Simone Meloni, Valeriia Lukashenko, Oscar De Aguiar Francisco, Harald Viemann, Alexander Leflat, Johannes Albrecht, Malcolm John, Nicola Skidmore, Leonid Kravchuk, Vasyl Dobishuk, Saverio Mariani, Vukan Jevtic, Alexey Zhelezov, Fedor Baryshnikov, Aravindhan Venkateswaran, Zhihao Xu, Cesar Luiz da Silva, Jia-Jia Qin, Themistocles Bowcock, Blaise Delaney, Amanda May Donohoe, William Parker, Donal Hill, Anna Ossowska, Nathan Jurik, Zhenzi Wang, Stanislav Poslavskii, Maxime Schubiger, Veronica Soelund Kirsebom, Pere Gironella Gironell, Kamil Leszek Fischer, Giovanni Passaleva, Thi Thuy Hang Pham, Daniele Marangotto, Marco Adinolfi, Adlène Hicheur, Benedict Donald C Westhenry, Emmy Gabriel, Alessandro Minotti, Benedetto Gianluca Siddi, Jascha Peter Grabowski, Yiheng Luo, Deepanwita Dutta, Mauro Morandin, Vitalii Lisovskyi, Lei Li, Laura Promberger, Vladislav Balagura, Zhiyu Xiang, Chung Nguyen-Mau, Frederic Teubert, David Gerick, Vinicius Franco Lima, Ina Carli, Preema Rennee Pais, Luis Miguel Garcia Martin, Gregory Ciezarek, Xiao-Rui Lyu, Matthias Karacson, Xiaotao Huang, Alessio Sarti, Hangyi Wu, Jakub Ryzka, F. Muheim, Philippe Ghez, Timothy Evans, Nuria Valls Canudas, Stefano Petrucci, Ignacio Bediaga, Desmond Mzamo Shangase, Cristina Sanchez Gras, Daniel Johnson, Matteo Salomoni, Thomas Harrison, Mariusz Witek, Chenxi Gu, Donatella Lucchesi, Evangelos Leonidas Gkougkousis, Paolo Gandini, Kurt Rinnert, Felipe Luan Souza De Almeida, John Walsh, David Sanchez Gonzalo, P. Spradlin, Patricia Camargo Magalhaes, Paul Soler, Jeremy Dalseno, Beat Jost, Tjeerd Ketel, Milosz Zdybal, L. Sun, Andrey Ustyuzhanin, Alexandru Ene, John Gordon Smeaton, Artem Ryzhikov, Sajan Easo, Bernardo Adeva, Guy Wilkinson, Guanghua Gong, Matthew Kenzie, Niels Tuning, Nis Meinert, Luciano Pappalardo, Kenenbek Arzymatov, Tamaki Holly Mcgrath, Alessia Satta, Dmitrii Pereima, Sai-Juan Chen, Oleksandr Zenaiev, Fedor Ratnikov, Jacco de Vries, Jibo He, Lex Marinus Greeven, Cameron Thomas Dean, Alberto dos Reis, Davide Brundu, Matteo Bartolini, Michal Kreps, Paolo Ciambrone, Youhua Yang, Daniel Berninghoff, Vincenzo Vagnoni, Colm Harold Murphy, Giovanni Carboni, Mauro Piccini, Christopher John Parkinson, Matthew Needham, Giovanni Cavallero, Joseph David Shupperd, Stefania Vecchi, Hanna Malygina, Edward Brendan Shields, Yixiong Zhou, Felipe Andres Garcia Rosales, Thomas Latham, Oleg Maev, Patrick Robbe, Lluis Garrido, Luigi Del Buono, Jinlin Fu, Alessandra Pastore, C. Patrignani, Alexey Dzyuba, V. Tisserand, Luca Tomassetti, Marie Bachmayer, Alessandro Cardini, Ifan Williams, Dawid Gerstel, Xabier Cid Vidal, Luca Minzoni, Dylan Jaide White, Michela Garau, Christoph Langenbruch, Gianluigi Casse, Paula Alvarez Cartelle, Jennifer Clare Smallwood, Jana Crkovská, Aleksandra Snoch, Lev Shekhtman, Pascal Perret, Fionn Caitlin Ros Bishop, Stefano Zucchelli, Quentin Fuehring, Phillip John Marshall, Mikhail Mikhasenko, Andrea Bizzeti, Kristof De Bruyn, Chishuai Wang, Dominik Stefan Mitzel, Marco Clemencic, Eluned Smith, Tommaso Colombo, Angelo Loi, Salvatore Aiola, Philip Ilten, Gloria Corti, Blake Leverington, Wojciech Krzemien, Benjamin Couturier, Gianfranco Morello, Mikkel Bjørn, Mark Slater, Pawel Kopciewicz, Jialu Wang, Raja Nandakumar, Aristeidis Fkiaras, Vladislav Belavin, Andrea Valassi, Tara Nanut, Carlos Vázquez Sierra, Roger Forty, Alexander Battig, Holger Stevens, Baasansuren Batsukh, Timothy Gershon, Imanol Corredoira, Daniel Joachim Unverzagt, Basem Khanji, Srishti Bhasin, Roberta Cardinale, Leandro De Paula, Claudio Gotti, Andrea Villa, Robbert Erik Geertsema, Zehua Xu, Daria Strekalina, Saverio Simone, Dominik Müller, Daniel Lacarrere, Felix Johannes Kress, Celestina Satriano, Eduard Ursov, Evelina Gersabeck, Barbara Passalacqua, Shunan Zhang, Jonathan Plews, Matthew John Bradley, Hongjie Mu, Richard Jacobsson, Malte Hecker, Mauricio Féo, Shantam Taneja, Thomas Blake, Yuyue Gan, Anatoly Butkevich, Marek Idzik, Liupan An, Mikhail Korolev, Gabriele Simi, Lukas Witola, Lino Ferreira Lopes, Albert Bursche, Anthony Gavin Downes, Joan Ruiz Vidal, Benjamin Audurier, Miriam Lucio Martinez, Jiangqiao Hu, Xavier Vilasis-Cardona, Thomas Hadavizadeh, Minaugas Sarpis, Sara Sellam, Denis Derkach, F. Ferreira Rodrigues, Julien Cogan, Giulia Tuci, Thi Dung Nguyen, Jussara De Miranda, Phoebe Meredith Hamilton, Eric Thomas, Xixin Liang, Almagul Kondybayeva, Tai-Hua Lin, Scott Ely, Burkhard Schmidt, Carlos Abellán Beteta, Jan Buytaert, Konstantin Belous, Giulia Frau, Lishuang Ma, Diego Alejandro Milanes, Giuseppe Martellotti, Henryk Karol Giemza, Mitesh Patel, B. Spaan, Sergey Barsuk, Ruiting Ma, Oliver Lantwin, Victor Egorychev, Valery Pugatch, Arnau Brossa Gonzalo, Emanuele Santovetti, Marina Artuso, Xiaofan Hu, Ryan Calladine, Floris Keizer, François Fleuret, Francesco Polci, Anastasiia Kharisova, Michael Sokoloff, Philipp Roloff, Federico Lazzari, Dong Xiao, Alberto Lusiani, Pierluigi Campana, Lesya Shchutska, Zhanwen Zhu, Michael Williams, Victor Coco, R. McNulty, Irina Nasteva, Pablo Baladron Rodriguez, Zhuoming Li, Michele Veltri, Roel Aaij, Vadym Denysenko, Sergei Popov, Eduardo Rodrigues, Abraham Gallas Torreira, Vladimir Romanovskiy, Melissa Maria Cruz Torres, Marie Helene Schune, James Vincent Mead, Daniel Hynds, Federico Stagni, Paula Garcia Moreno, Donal Murray, Christophe Haen, Clara Matteuzzi, Biplab Dey, Martinus van Beuzekom, Pascal Vincent, Marcel Materok, Fergus Wilson, Alina Zharkova, Rizwaan Adeeb Mohammed, Alexsei Chubykin, Maarten Van Dijk, Elena Graverini, Olivier Deschamps, Niklas Stefan Nolte, Flavio Archilli, Matteo Palutan, A. Bay, Mikhail Shapkin, G. Raven, Alexander Bondar, Lingzhu Bian, Darya Savrina, Shiyang Li, Sergio Gomez Fernandez, Naomi Cooke, Andrea Mauri, Wenbin Qian, Menglin Xu, Loris Martinazzoli, Ao Xu, Mara Senghi Soares, Jakob Haimberger, Elisabeth Maria Niel, Sonia Amina Bouchiba, Adam Dendek, Yuehong Xie, Anastasia Smetkina, Mark Whitehead, Lucas Mcconnell, Semen Eidelman, Konrad Klimaszewski, Anatoly Konoplyannikov, Maciej Pawel Szymanski, Jakub Jacek Malczewski, Guillaume Pietrzyk, Danila Saranin, Andrii Usachov, Marco Pappagallo, Paul Seyfert, Abhijit Mathad, Daniel Vieira, Ming Zeng, Tommaso Pajero, Andrew Beiter, Lars Eklund, Leon David Carus, Alexander Bitadze, Beatriz Garcia Plana, Yanxi Zhang, Oscar Boente Garcia, Sebastian Neubert, Martha Hilton, Cynthia Nunez, Conor Fitzpatrick, Antonino Sergi, Mark Tobin, Dmitrii Ilin, Yanting Fan, Alexey Vorobyev, Ziad Ajaltouni, Liliet Calero Diaz, Gianluca Zunica, Eleonora Luppi, Robert Currie, Edward James Millard, Marco Gersabeck, Andrey Golutvin, I. V. Gorelov, Giovanni Bassi, Shuangli Yang, John Back, Christoph Hasse, Christopher James Pawley, Lukas Calefice, Christopher Burr, Maria Elena Stramaglia, Michele Piero Blago, Zhihong Shen, Hao Cai, Dillon Scott Fitzgerald, Andreas Güth, Frederic Machefert, Sheldon Stone, Peter Svihra, Jifeng Hu, Yilong Wang, Peilian Li, Domenico Galli, Maximo Plo Casasus, E. Grauges, Joel Closier, Luis Alberto Granado Cardoso, John Jake Lane, Rudolf Oldeman, Joao A B Coelho, Massimiliano Fiorini, Ryunosuke Hugo O'Neil, Miriam Calvo Gomez, Carla Marin Benito, Evgeny Gushchin, Ilaria Neri, Oliver Lupton, Artur Ishteev, Stefano De Capua, Umberto Marini Bettolo Marconi, Silvia Gambetta, Sergei Kholodenko, Simon Akar, Christopher Jones, Raymond Mountain, Markus Frank, Kimberley Vos, Naylya Sagidova, Maurizio Martinelli, Francesca Dordei, Paolo Durante, Karlis Dreimanis, Sophie Elizabeth Hollitt, Carina Trippl, Lucia Grillo, Aleksandr Solovev, David Websdale, Bartosz Malecki, Roland Bernet, Nikolay Nikitin, Philippe d'Argent, Massimiliano Ferro-Luzzi, Alexander Semennikov, Sebastien Ponce, Kayleigh Anne Thomson, Daniele Manuzzi, Nikolai Voropaev, Paras Naik, Zoltan Mathe, Bruno Souza De Paula, Wouter Hulsbergen, Marco Guarise, Kevin Heinicke, Kara Renee Mattioli, Mateusz Goncerz, Barbara Sciascia, Boris Quintana, Jordan Daniel Roth, Hossein Afsharnia, Julian Lomba Castro, Agnieszka Oblakowska-Mucha, Maik Becker, André Massafferri, Martina Ferrillo, Juan Jose Saborido Silva, Ettore Zaffaroni, Adam Szabelski, Krzysztof Swientek, Ning Qin, Olga Madejczyk, Franco Bedeschi, Simone Capelli, Brian Meadows, Roberta Santacesaria, Mick Mulder, Antonio Pellegrino, F. Blanc, Jingzhou Fan, Peter Clarke, Murilo Rangel, Dmitry Popov, Tatsuya Nakada, Olaf Steinkamp, G. Bencivenni, Viacheslav Matiunin, Marco Cattaneo, Michel De Cian, Michele Atzeni, Li Xu, Hannah Louise Pullen, Surapat Ek-In, Yang Li, Miroslaw Firlej, Lauren Emma Yeomans, Elena Dall'Occo, Paolo Carniti, Meril Reboud, Ana Barbara Rodrigues, Alexander Berezhnoy, Alexander Mclean Marshall, Vladimir Shevchenko, Elisabet Golobardes, Xianglei Zhu, Di Yang, Sergey Didenko, Simone Bifani, Stephen Wotton, Nigel Watson, Marcelo Soares, Jakub Moron, Kodassery Prasanth, Zhenwei Yang, Richard Lane, Gediminas Sarpis, Matthew Scott Rudolph, Manuel Franco Sevilla, Adam Benjamin Morris, Georgios Chatzikonstantinidis, Samuel Maddrell-Mander, A. Alfonso Albero, G. Wormser, Violaine Bellee, Miguel Ramos Pernas, Vladimir Chulikov, Alessandra Gioventù, Philippe Charpentier, Serhii Cholak, Renata Kopecna, Sook Hyun Lee, Christoph Frei, Rainer Schwemmer, Andrew McNab, Pasquale Di Nezza, Hans Peter Dembinski, Gary Robertson, Sergey Gromov, Gaia Lanfranchi, Bhagyashree Pagare, Louis Henry, Hilbrand Steffen Kuindersma, Rosa Anna Fini, Tomasz Fiutowski, Qingnian Xu, P. Collins, Gerwin Meier, Serena Maccolini, Jan Patrick Hammerich, Jörg Marks, C. A. Chavez Barajas, Claire Prouve, Gennady Panshin, Neville Harnew, Giovanni Valenti, Davide Pinci, Patrick Owen, Michael Joseph Morello, Giampiero Mancinelli, Fabrice Desse, Vladimir Gligorov, Kuzma Ivshin, Igancio Alberto Monroy, Marcello Rotondo, Philipp Ibis, Fernando Martinez Vidal, Pavol Stefko, Jordy Sebastiaan Butter, Marcin Kucharczyk, Maximilien Chefdeville, Maciej Witold Majewski, Adam Davis, Alessandro Scarabotto, Aleksei Andreianov, E. Ben-Haim, Alessandro Di Cicco, Jingyi Xu, Harry Cliff, Steffen Georg Weber, Wander Baldini, Victor Renaudin, Iain Longstaff, Adrian Casais Vidal, Sandra Amato, Petr Andreevich Gorbounov, Jolanta Brodzicka, Biljana Mitreska, Juan Martin Otalora Goicochea, Laurent Dufour, and Nicola Neri
Subjects: Baryon, Physics, 010308 nuclear & particles physics, Branching fraction, Excited state, 0103 physical sciences, Pi, Center of mass, Atomic physics, 010306 general physics, Spin (physics), 01 natural sciences, Luminosity
Abstract: The first observation of the Ω b - → Ξ c + K - π - decay is reported using p p collision data at center of mass energies of 7, 8, and 13 TeV collected by the LHCb experiment, corresponding to an integrated luminosity of 9 fb - 1 . Four excited Ω c 0 baryons are observed in the Ξ c + K - mass projection of the Ω b - → Ξ c + K - π - decays with the significance of each exceeding five standard deviations. They coincide with the states previously observed in prompt p p and e + e - production. Relative production rates, masses, and natural widths of the states are measured, and a test of spin hypotheses is performed. Moreover, the branching ratio of Ω b - → Ξ c + K - π - is measured relative to the Ω b - → Ω c 0 π - decay mode and a precise measurement of the Ω b - mass of 6044.3 ± 1.2 ± 1. 1 - 0.22 + 0.19 MeV is obtained.
Published: 2021

49. Thermal decomposition and volatility of ionic liquids: Factors, evaluation and strategies

Author: Yu Chen, Xiaoxue Han, Zhenghui Liu, Yuting Li, Haiyang Sun, Han Wang, and Jianqiang Wang
Subjects: Materials Chemistry, Physical and Theoretical Chemistry, Condensed Matter Physics, Spectroscopy, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published: 2022

50. Effect of Mn-dopant on carburization of the Fe3O4 catalysts in Fischer-Tropsch synthesis

Author: Jing Lv, Xiaoxue Han, Xinbin Ma, Ying Li, Yifei Wang, Shouying Huang, Yue Wang, and Huiyong Gong
Subjects: Materials science, Dopant, General Chemical Engineering, Oxide, Nanoparticle, Fischer–Tropsch process, General Chemistry, Industrial and Manufacturing Engineering, Catalysis, chemistry.chemical_compound, Chemical engineering, chemistry, X-ray photoelectron spectroscopy, Carburization, Mn doping, Fischer–Tropsch synthesis, Density functional theory, TP155-156, Fe3O4 nanoparticles, Syngas
Abstract: By experimental and density functional theory (DFT) methods, we investigated the effect of Mn on the carburization of the Fe3O4 catalysts in Fischer–Tropsch synthesis. Freshly prepared MnxFe3-xO4 (x = 0, 0.27 and 1) nanoparticles as representative model bulk FTS catalysts were carburized by exposing to syngas. The oxide nanoparticles and the corresponding carburized samples were then characterized using XRD, XPS, TEM and MES. To mimic the experiments, a slab modelling the Fe3O4(3 1 1) surface doped with different number of Mn atoms were constructed in the DFT calculations. Our results showed that Mn doping hindered the carburization of Fe3O4 nanoparticles and stabilizes the reduction intermediate at FeO. This is attributed to the enhanced affinity of O atoms in the presence of Mn-dopant, making removal of O difficult. The work provides guidance for catalysts design and activation for FTS process.
Published: 2021

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