Search

Abstract Objective To investigate the effects of sufentanil on immune response, pain mediators and brain-sparing effect in patients with breast cancer undergoing radical mastectomy. Methods This study was a single center retrospective cohort study. The 118 study subjects were diagnosed and treated in our hospital from the period of January 2020-October 2022, who planned to undergo radical surgery for breast cancer. According to the different surgical drugs, these subjects were divided into sufentanil group and the control group, with 59 cases each. The visual analog scores (VAS) of patients in two groups were compared at 24 hour and 48 hour after surgery. The immune response indexes (including CD3+, CD4+, CD8+, CD4+/CD8+), pain mediators (β-endorphin, substance P and 5-hydroxytryptophan), brain-sparing effect indexes [arterio-venous oxygen content difference (Da-jvO2), jugular bulb venous saturation (S-jvO2), cerebral oxygen uptake (CEO2) and the Mini Mental State Scale (MMSE)], and brain damage indexes [S100 calcium-binding protein B (S100B) and neuron-specific enolase (NSE)] in two groups were compared. The incidence of adverse reactions in two groups was compared. Results VAS scores were obviously lower in the sufentanil group than the control group at 24 hour and 48 hour postoperatively (P

The G protein-coupled receptor Opsin 3 is critical for supranuclear cap formation mediated by solar ultraviolet radiation in human epidermal keratinocytes.

Cloud computing system has the characteristics of large-scale servers and a wide range of users.However, it also consumes a huge number of energy, resulting in high operating costs of cloud providers and high carbon emissions issue.Cloud computing is highly virtualized.How to allocate and manage the virtual resources to ensure efficient physical resource utilization and energy consumption control is a multi-parameter game problem, and it is also a research hotspot in this field.A virtual machine scheduling model and the corresponding SV-GA were proposed, which could calculate the contribution value of the physical machine participating in the work through the Shapley value, and modify the probability parameter of the mutation step in the genetic algorithm through the contribution value, so as to complete the task of virtual machine scheduling.The experimental results show that during the comparison with Max-Min, LrMmt and DE, the SV-GA shows its excellent performance in the multi-parameter game including migration time, times, SLA violation rate and energy consumption in the virtual machine scheduling process.

Practical and theoretical advancements have not caught pace with rising scientific researches in the rapidly emerging economy undertaking a shift to a more sustainable and particularly green model. After the UN adopted the 2030 Agenda for Sustainable Development, there has been a surge in interest in the green economy among academics around the world, and the literature on the issue is proliferating. This paper adopts the methodology of bibliometric review and thematic analysis to summarize the relevant literature from 2016 to 2022 on areas related to the theme of green economy. The literature was obtained from the Web of Science database with a total of 1,022 articles. Furthermore, the literature was analyzed using VOSviewer as well as the R language to couple the literature by keywords, country, affiliation, author, and publication. The findings of the current paper show that the green economy has received more academic attention from scholars since 2016. Asia and Europe are leaders in green economy studies. In the context of climate change, future research is anticipated to concentrate on establishing a green economy for global economic growth. This paper makes a substantial contribution to future research on the green economy.

The objective of the current study is to perform a systematic review to the published articles upon the advancement of corporate social responsibility (CSR) in the service sector. This article analyzes the bibliometric information of the CSR-related articles linked to the service sector. The existing literature on CSR in the service industry were derived from the online WOS indexing dataset. Through completing a systematic review on existing academic articles, the current paper identifies the nations, universities/institutions, prolific researchers, high-profile journal that contributed to the advancement of CSR theory and practical applications. Moreover, the analytical graphs and bibliometric coupling shown the keyword co-occurrence to depict the academic relationship on the CSR advancement in the service industry. The systematic review adds to an in-depth knowledge of the progression behind CSR in the corporate environment and extends the CSR nexus researches.

Abstract Recently, monolayer CoSb/SrTiO3 has been proposed as a candidate harboring interfacial superconductivity in analogy with monolayer FeSe/SrTiO3. Experimentally, while the CoSb-based compounds manifesting as nanowires and thin films have been realized on SrTiO3 substrates, serving as a rich playground, their electronic structures are still unknown and yet to be resolved. Here, we have fabricated CoSb1−x nanoribbons with quasi-one-dimensional stripes on SrTiO3(001) substrates using molecular beam epitaxy and investigated the electronic structure by in situ angle-resolved photoemission spectroscopy. Straight Fermi surfaces without lateral dispersions are observed. CoSb1−x /SrTiO3 is slightly hole doped, where the interfacial charge transfer is opposite to that in monolayer FeSe/SrTiO3. The spectral weight near the Fermi level exhibits power-law-like suppression and obeys a universal temperature scaling, serving as the signature of Tomonaga–Luttinger liquid (TLL) state. The obtained TLL parameter of ~0.21 shows the underlying strong correlations. Our results not only suggest CoSb1−x nanoribbon as a representative TLL system but also provide clues for further investigations on the CoSb-related interface.

Abstract Background Information about global and local epidemiology and trends of skin cancers is limited, which increases the difficulty of cutaneous cancer control. Methods To estimate the global spatial patterns and temporal trends of skin cancer burden. Based on the GBD 2019, we collected and analyzed numbers and age‐standardized rates (ASR) of skin cancer incidence, disability‐adjusted life years (DALYs) and mortality (ASIR, ASDR, and ASMR) in 204 countries from 1990 through 2019 were estimated by age, sex, subtype (malignant skin melanoma [MSM], squamous‐cell carcinoma [SCC], and basal‐cell carcinoma [BCC]), Socio‐demographic Index (SDI), region, and country. Temporal trends in ASR were also analyzed using estimated annual percentage change. Results Globally, in 2019, there were 4.0 million BCC, 2.4 million SCC, and 0.3 million MSM. There were approximately 62.8 thousand deaths and 1.7 million DALYs due to MSM, and 56.1 thousand deaths and 1.2 million DALYs were attributed to SCC, respectively. The men had higher ASR of skin cancer burden than women. The age‐specific rates of global skin cancer burden were higher in the older adults, increasing trends observed from 55 years old. Geographically, the numbers and ASR of skin cancers varied greatly across countries, with the largest burden of ASIR in high SDI regions. However, an unexpected increase was observed in some regions from 1990 to 2019, such as East Asia, and Sub‐Saharan Africa. Although there was a slight decrease of the ASMR and ASDR, the global ASIR of MSM dramatically increased, 1990–2019. Also, there was a remarkable increase in ASR of BCC and SCC burden. Conclusions Skin cancer remains a major global public health threat. Reducing morbidity and mortality strategies such as primary and secondary prevention should be reconsidered, especially in the most prevalent and unexpected increased regions, especially for those areas with the greatest proportions of their population over age 55.

Abstract Background Classic Kaposi sarcoma (CKS) is a vascular sarcoma associated with human herpesvirus 8 (HHV-8), which is known to be more common in Mediterranean elderly men and is characterized by indolent clinical behavior. Xinjiang province in China is considered an endemic region for Kaposi’s sarcoma-associated herpesvirus (KSHV), with higher incidence among adults of Kazak and Uyghur ethnicities. Cases of CKS are rarely reported in inland China. Here, we followed a case of CKS for 7 years in a patient of Miao ethnic background in southwestern China. Case presentation A 63-year-old Miao (southwestern China) man was initially diagnosed with CKS in 2010, having a history of limb lesions for 37 years, with left eyelid and binaural lesions for 9 years. He did not have sexual contact with men and was human immunodeficiency virus (HIV)-negative. Due to his lumbago and fever, spinal tuberculosis in the lumbar vertebra was highly suspected after computed tomography (CT) scan. However, diagnostic antituberculosis treatment for 4 weeks failed. The patient was followed up in 2016, when the rash was recovering as the systemic symptoms improved. A new CT was performed, which showed a partial response despite the absence of any medical treatment. The open reading frame (ORF)-K1 of KSHV from skin tissue of the foot was amplified and sequenced, and K1 belonged to subtype A. This genotype is consistent with the typical subtype present in Xinjiang. Conclusions We describe spontaneous partial regression of CKS in a patient of Miao ethnicity in inland China. Our sample may represent an unknown, novel genotype. Surveillance and regulating the immune state may represent a valuable approach for this rare disease.

Abstract Stretchable structural colors that can dynamically respond to mechanical stimuli are garnering interest as energy‐free mechanical‐optical sensors. Typical technologies for embedding photonic crystals (PCs) in elastic hydrogels generally involve etching processes, which have raked controversy for straying from green manufacturing practices. Here, a facile pressure‐assisted self‐assembly strategy to fabricate an interfacial photonic structure, i.e., semicrystalline photonic structure (SPS), consisting of two diffraction nanopatterns, including randomly oriented, medium‐scale ordered PCs and arbitrarily distributed amorphous photonic glass using hydrophilically modified colloidal polystyrene (PS) nanospheres configured at the hydrogel interface is introduced. The structural colors of the SPS hydrogel interfaces undergo immediate and repeatable mechanochromic redshift or blueshift in real time when the sample is longitudinally compressed or tensed, respectively, at both the micro zone and macroscopic color block levels. The SPS hydrogel interfaces display long‐term colorfast, angle‐independent, or non‐iridescent coloration and bright structural colors in a high reflective‐intensity range of 62%–96% at a normal viewing angle. With these features, this study demonstrates the feasibility of fabricating SPS hydrogel interfaces with mechanical and optical properties that are compatible with state‐of‐the‐art stretchable optical sensors.

ABSTRACTScabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unravelled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. The prevalence and incidence of scabies tend to a moderate increase after age 70. The annual percentage change in ASR of scabies prevalence and incidence increased in high SDI countries and High-income North America. Current prevention strategies should be reoriented, and much more targeted strategies should be established in some populations to forestall the increase in scabies.

A highly controversial topic, the mechanism of the anodization of the formation of porous structures of metals is still believed by many researchers to be field-assisted dissolution by fluoride ions. In this paper, evidence against this mechanism is provided. Using SEM images of titanium oxides anodized in four fluoride-free electrolytes—NaNO3, KNO3, H2SO4, and H3PO4 solutions—and the corresponding current−time curves, this paper supports the newly grown oxides growing upward around the oxygen bubble mold in a viscous flow mode to form nanotubes. The electronic current is high enough to ensure the continuous release of oxygen gas, which is necessary to form nanotubes, such as in NaNO3 and KNO3 solutions. When the electronic current is small enough, the oxygen bubbles can only form porous structure similar to those found in bread, such as in H2SO4 and H3PO4 solutions.

The use of the C-expander is an effective treatment modality for maxillary skeletal deficiencies which can cause ailments and significantly reduce life expectancy in late adolescents and young adults. However, the morphological and dynamic effects on the nasal airway have not been reported. The main goal of this study was to evaluate the nasal airway changes after the implementation of a C-expander. A sample of nine patients (8 females, 1 male, age range from 15 to 29 years) was included. The morphology parameters and nasal airway ventilation parameters of pretreatment and posttreatment were measured. All study data were normally distributed. A paired t-test was used to evaluate the changes before and after treatment. After expansion, the mean and standard deviation values of intercanine maxillary width (CMW) and intermolar maxillary width (MMW) increased from 35.75±2.48 mm and 54.20±3.17 mm to 37.87±2.26 mm (P

Highly ordered porous anodic alumina (PAA) is widely used as a template for preparing one-dimensional nanostructured materials. At present, research efforts to prepare PAA templates with straight channels mainly focus on improving their regularity or increasing the efficiency of the preparation methods. Herein, we introduce a novel anodization method to fabricate highly ordered PAA films based on closed bipolar electrochemistry. To the best of our knowledge, there have been no reports of the use of closed bipolar electrochemistry in PAA film fabrication. Compared to traditional anodization, a faster PAA film growth rate of 1.67 μm min−1 was obtained in 0.75 M oxalic acid when a voltage of 62 V was applied to the driving electrodes. Furthermore, different electrolyte solutions can be employed in the anodic and cathodic cells in the closed bipolar electrochemical system. In addition, no direct electrical connection to the aluminum sheets is required in this approach.

Background: Balance training may be beneficial for patients with osteoporosis, although current results are inconclusive. The aim of this systematic review and meta-analysis was to explore the effect of balance training on falls in patients with osteoporosis. Methods: PubMed, Embase, Web of Science, EBSCO, and Cochrane Library databases were systematically searched. Randomized controlled trials (RCTs) assessing the effect of balance training vs usual activities on falls in patients with osteoporosis were included. Two investigators independently searched articles, extracted data, and assessed the quality of included studies. The primary outcome was fall frequency. This meta-analysis was performed using the fixed- or random-effect model when appropriate. Results: Six RCTs were included in the systematic review and 3 in the meta-analyses. Compared with control groups, a balance training intervention was found to significantly reduce the frequency of falls (risk ratio = 0.63; 95% confidence interval (95% CI) 0.42–0.95; p = 0.03) in patients with osteoporosis, but demonstrated no remarkable influence on the results of the Berg Balance Scale (mean difference –3.66; 95% CI –12.04–4.72; p = 0.39) and Timed Up and Go test (mean difference –1.79; 95% CI –6.05–2.47; p = 0.41). Conclusion: Balance training may significantly reduce the frequency of falls in patients with osteoporosis.

Poplar wood fibers (WFs) were pretreated with ionic liquid (IL) 1-butyl-3-methylimidazolium chloride ([C4mim]Cl) at 125 °C for 1 h, and the influence of the wood loadings (5%, 15%, 30%, and 50%) on the pretreatment efficiency and downstream acetylation was studied. The crystallinity and lignin content of the WFs decreased after IL pretreatment at low wood loadings, especially at 5%. Wood fiber acetylation was performed under a molar ratio (acetic anhydride/–OH in the WFs) of 2:1, with toluene as the reaction medium and pyridine as the acid capturer. Ionic liquid pretreatment at 5% and 15% loading greatly contributed to the increase of weight percent gain (WPG) after acetylation, leading to much higher reaction efficiency, or lower energy consumption. The acetylated products that underwent pretreatment (mainly at 5% loading) had slightly higher thermal stability than those that did not undergo pretreatment. The crystallinity and moisture sorption ability of the products were determined primarily by the WPG value.

Human occupancy detection (HOD) in an enclosed space, such as indoors or inside of a vehicle, via passive cognitive radio (CR) is a new and challenging research area. Part of the difficulty arises from the fact that a human subject cannot easily be detected due to spectrum variation. In this paper, we present an advanced HOD system that dynamically reconfigures a CR to collect passive radio frequency (RF) signals at different places of interest. Principal component analysis (PCA) and recursive feature elimination with logistic regression (RFE-LR) algorithms are applied to find the frequency bands sensitive to human occupancy when the baseline spectrum changes with locations. With the dynamically collected passive RF signals, four machine learning (ML) classifiers are applied to detect human occupancy, including support vector machine (SVM), k-nearest neighbors (KNN), decision tree (DT), and linear SVM with stochastic gradient descent (SGD) training. The experimental results show that the proposed system can accurately detect human subjects—not only in residential rooms—but also in commercial vehicles, demonstrating that passive CR is a viable technique for HOD. More specifically, the RFE-LR with SGD achieves the best results with a limited number of frequency bands. The proposed adaptive spectrum sensing method has not only enabled robust detection performance in various environments, but also improved the efficiency of the CR system in terms of speed and power consumption.

Al-based glassy alloys (metallic glasses) have been of great scientific and technological interest as a high specific strength and high corrosion resistant materials. However, the low glass-forming ability (GFA) is still a choke point that greatly influences the applications. In order to further comprehend the glass formation mechanism and investigate the possibility of enhancing the GFA, it is important to obtain the definite information on the atomic scale glassy structures in correlation with properties and to study the composition dependence of crystallization and properties of Al-based metallic glasses. The purpose of this paper is to summarize the structure characteristics and crystallization behavior in conjunction with alloy component in Al-based metallic glasses and to investigate the possibility of synthesizing an Al-based bulk metallic glass with better engineering performances. This may assist to learn the structural features systematically and understand the development and current status for Al-based metallic glasses.

In the title complex, [Co(C2N3)2(C12H12N6)2]n the CoII atom lies on a centre of symmetry and displays a slightly distorted octahedral coordination geometry. The 1,2-bis[(1,2,4-triazol-1-yl)methyl]benzene ligands link adjacent metal atoms into polymeric chains parallel to the c axis, forming centrosymmetric 26-membered metallamacrocycles. The conformation of the metallamacrocycles is stabilized by pairs of C—H...N hydrogen bonds. The dihedral angles formed by the planes of the triazole rings with those of the benzene ring are 79.4 (2) and 79.1 (2)°. In the crystal, the chains interact through C—H...N hydrogen bonds, forming a three-dimensional network.

Nearly monodispersed Ag3PO4 nanocrystals with size of 10 nm were prepared through a colloidal chemical route. It was proven that the synthesized Ag3PO4 nanoparticles have intrinsic peroxidase-like catalytic activity. They can quickly catalyze oxidation of the peroxidase substrate 3, 3, 5, 5-tetramethylbenzidine (TMB) in the presence of H2O2, producing a blue color. The catalysis reaction follows Michaelis-Menten kinetics. The calculated kinetic parameters indicate a high catalytic activity and the strong affinity of Ag3PO4 nanocrystals to the substrate (TMB). These results suggest the potential applications of Ag3PO4 nanocrystals in fields such as biotechnology, environmental chemistry, and medicine.

In the title compound, C19H13N3O, the dihedral angle between the two quinoline systems is 11.54 (3)°. The molecular conformation is stabilized by intramolecular N—H...N and C—H...O hydrogen bonds, with N—H...N being bifurcated towards the two N atoms of the two quinoline rings. In the crystal, there are weak intermolecular π–π interactions present involving the quinoline rings [centroid–centroid distance 3.7351 (14) Å].

In the title compound, (C16H36N)[Fe(C12H8N3O2)(CN)3]·2H2O, the tetra-n-butylammonium ion has a tetrahedral configuration around the N atom, while the FeIII atom of the tricyanido[N-(2-pyridylcarbonyl)pyridine-2-carboximidato]iron(III) anion adopts a distorted octahedral geometry. O—H...O and O—H...N hydrogen bonds link the components in the crystal structure.

In the title compound, [Fe(C12H8N3O2)2][Fe(C12H8N3O2)(CN)3]·H2O, the Fe3+ ions in the cation and anion each lie in a slightly distorted octahedral coordination environment. The solvent water molecule is disordered over three positions with occupancies of 0.401 (7), 0.322 (7) and 0.277 (6). The water content was confirmed by thermogravimetric data.

During the cantilever casting process of reinforced concrete arch bridges with cantilever cast‐in‐situ method, it is difficult to select representative training samples for reliability analysis due to its complex structural system. Many random variables and large computational sample size, this paper proposes to solve the reliability indexes based on the combination of the improved sparrow search algorithm (LGSSA) and the support vector regression (SVR) method. Firstly, random variables are selected according to the actual situation of the bridge structure. Then representative training samples are designed to be substituted into the finite element model through the homogeneous method. The resultant data samples are used to fit the functional function by the support vector regression. Then combined with the penalized function method to transform the nonlinear optimization into the problem of solving the extreme value of the function. Based on the improved SSA to solve the extreme value of the final function. Finally the reliability index of the structure is obtained. With the background of reinforced concrete arch bridge of 200 m, the method is used to analyze the reliability of its buckling cable stress, arch stress, buckling tower deviation and structural system reliability during the cantilever casting process. The results show that the overall structural reliability of the arch ring during cantilever casting is 3.502–3.608. The indexes of buckling cable stress reliability are 3.806–6.784. The indexes of arch ring stress reliability are 4.379–7.562, and the indexes of buckling tower deflection reliability are 3.608–8.123. [ABSTRACT FROM AUTHOR]