1. Dietary factors in relation to hypertension: a mendelian randomization study
- Author
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Jiasheng Cai, Xiaochen Sun, Mingxuan Li, Rong Luo, Wei Wang, Zilong Wang, Mohammed Ahmed Akkaif, and Haibo Liu
- Subjects
Dietary factors ,Hypertension ,Mendelian randomization study ,Single nucle-otide polymorphisms ,Cardiovascular disease ,Nutritional diseases. Deficiency diseases ,RC620-627 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Observational studies have elucidated the associations between dietary factors and hypertension. Nevertheless, the exploration of these relationships using Mendelian randomization remains scarce currently. Methods The Mendelian randomization approach investigated the potential causal relationships between 16 dietary factors and hypertension. To achieve this, we identified genetic variants associated with these dietary factors by utilizing data from European-descent genome-wide association studies with a stringent significance threshold (P
- Published
- 2024
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