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Rapid urbanization has led to the expansion of Shenzhen’s built-up land and a substantial reduction in urban greenspace (UG). However, the changes in UG in Shenzhen are not well understood. Here, we utilized long-time-series land cover data and the Normalized Difference Vegetation Index (NDVI) as a proxy for greenspace quality to systematically analyze changes in the spatio-temporal pattern and the exposure and inequality of UG in Shenzhen. The results indicate that the UG area has been decreasing over the years, although the rate of decrease has slowed in recent years. The UG NDVI trend exhibited some seasonal variations, with a noticeable decreasing trend in spring, particularly in the eastern part of Shenzhen. Greenspace exposure gradually increased from west to east, with Dapeng and Pingshan having the highest greenspace exposure regardless of the season. Over the past two decades, inequality in greenspace exposure has gradually decreased during periods of urban construction in Shenzhen, with the fastest rate of decrease in spring and the slowest rate of decrease in summer. These findings provide a scientific basis for a better understanding of the current status of UG in Shenzhen and promote the healthy development of the city. Additionally, this study provides scientific evidence and insights for relevant decision-making institutions.

BackgroundThe goal is to establish and validate an innovative prognostic risk stratification and nomogram in patients of hepatocellular carcinoma (HCC) with microvascular invasion (MVI) for predicting the cancer-specific survival (CSS).Methods1487 qualified patients were selected from the Surveillance, Epidemiology and End Results (SEER) database and randomly assigned to the training cohort and validation cohort in a ratio of 7:3. Concordance index (C-index), area under curve (AUC) and calibration plots were adopted to evaluate the discrimination and calibration of the nomogram. Decision curve analysis (DCA) was used to quantify the net benefit of the nomogram at different threshold probabilities and compare it to the American Joint Committee on Cancer (AJCC) tumor staging system. C-index, net reclassification index (NRI) and integrated discrimination improvement (IDI) were applied to evaluate the improvement of the new model over the AJCC tumor staging system. The new risk stratifications based on the nomogram and the AJCC tumor staging system were compared.ResultsEight prognostic factors were used to construct the nomogram for HCC patients with MVI. The C-index for the training and validation cohorts was 0.785 and 0.776 respectively. The AUC values were higher than 0.7 both in the training cohort and validation cohort. The calibration plots showed good consistency between the actual observation and the nomogram prediction. The IDI values of 1-, 3-, 5-year CSS in the training cohort were 0.17, 0.16, 0.15, and in the validation cohort were 0.17, 0.17, 0.17 (P

An accurate spatial distribution map of the urban dominant tree species is crucial for evaluating the ecosystem service value of urban forests and formulating urban sustainable development strategies. Spaceborne hyperspectral remote sensing has been utilized to distinguish tree species, but these hyperspectral data have a low spatial resolution (pixel size ≥ 30 m), which limits their ability to differentiate tree species in urban areas characterized by fragmented patches and robust spatial heterogeneity. Zhuhai-1 is a new hyperspectral satellite sensor with a higher spatial resolution of 10 m. This study aimed to evaluate the potential of Zhuhai-1 hyperspectral imagery for classifying the urban dominant tree species. We first extracted 32 reflectance bands and 18 vegetation indices from Zhuhai-1 hyperspectral data. We then used the random forest classifier to differentiate 28 dominant tree species in Shenzhen based on these hyperspectral features. Finally, we analyzed the effects of the classification paradigm, classifier, and species number on the classification accuracy. We found that combining the hyperspectral reflectance bands and vegetation indices could effectively distinguish the 28 dominant tree species in Shenzhen, obtaining an overall accuracy of 76.8%. Sensitivity analysis results indicated that the pixel-based classification paradigm was slightly superior to the object-based paradigm. The random forest classifier proved to be the optimal classifier for distinguishing tree species using Zhuhai-1 hyperspectral imagery. Moreover, reducing the species number could slowly improve the classification accuracy. These findings suggest that Zhuhai-1 hyperspectral data can identify the urban dominant tree species with accuracy and holds potential for application in other cities.

BackgroundHepatocellular carcinoma (HCC) has the highest cancer-related mortality rate. This study aims to create a nomogram to predict the cancer-specific survival (CSS) in patients with advanced hepatocellular carcinoma.MethodsPatients diagnosed with advanced HCC (AJCC stage III and IV) during 1975 to 2018 were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Qualified patents were randomized into training cohort and validation cohort at a ratio of 7:3. The results of univariate and multivariate Cox regression analyses were used to construct the nomogram. Consistency index (C-index), area under the time-dependent receiver operating characteristic (ROC) curve [time-dependent area under the curve (AUC)], and calibration plots were used to identify and calibrate the nomogram. The net reclassification index (NRI), integrated discrimination improvement (IDI), and C-index, and decision curve analysis DCA were adopted to compare the nomogram’s clinical utility with the AJCC criteria.ResultsThe 3,103 patients with advanced hepatocellular carcinoma were selected (the training cohort: 2,175 patients and the validation cohort: 928 patients). The C-index in both training cohort and validation cohort were greater than 0.7. The AUC for ROC in the training cohort was 0.781, 0.771, and 0.791 at 1, 2, and 3 years CSS, respectively. Calibration plots showed good consistency between actual observations and the 1-, 2-, and 3-year CSS predicted by the nomogram. The 1-, 2-, and 3-year NRI were 0.77, 0.46, and 0.48, respectively. The 1-, 2-, and 3-year IDI values were 0.16, 0.15, and 0.12 (P < 0.001), respectively. DCA curves in both the training and validation cohorts demonstrated that the nomogram showed better predicted 1-, 2-, and 3-year CSS probabilities than AJCC criteria.ConclusionsThis study established a practical nomogram for predicting CSS in patients with advanced HCC and a risk stratification system that provided an applicable tool for clinical management.

ObjectiveHepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. This study aims to construct a novel practical nomogram and risk stratification system to predict cancer-specific survival (CSS) in HCC patients with severe liver fibrosis.MethodsData on 1,878 HCC patients with severe liver fibrosis in the period 1975 to 2017 were extracted from the Surveillance, Epidemiology, and End Results database (SEER). Patients were block-randomized (1,316 training cohort, 562 validation cohort) by setting random seed. Univariate and multivariate COX regression analyses were employed to select variables for the nomogram. The consistency index (C-index), the area under time-dependent receiver operating characteristic curve (time-dependent AUC), and calibration curves were used to evaluate the performance of the nomogram. Decision curve analysis (DCA), the C-index, the net reclassification index (NRI), and integrated discrimination improvement (IDI) were used to compare the nomogram with the AJCC tumor staging system. We also compared the risk stratification of the nomogram with the American Joint Committee on Cancer (AJCC) staging system.ResultsSeven variables were selected to establish the nomogram. The C-index (training cohort: 0.781, 95%CI: 0.767–0.793; validation cohort: 0.793, 95%CI = 95%CI: 0.779–0.798) and the time-dependent AUCs (the training cohort: the values of 1-, 3-, and 5 years were 0.845, 0.835, and 0.842, respectively; the validation cohort: the values of 1-, 3-, and 5 years were 0.861, 0.870, and 0.876, respectively) showed satisfactory discrimination. The calibration plots also revealed that the nomogram was consistent with the actual observations. NRI (training cohort: 1-, 2-, and 3-year CSS: 0.42, 0.61, and 0.67; validation cohort: 1-, 2-, and 3-year CSS: 0.26, 0.52, and 0.72) and IDI (training cohort: 1-, 3-, and 5-year CSS:0.16, 0.20, and 0.22; validation cohort: 1-, 3-, and 5-year CSS: 0.17, 0.26, and 0.30) indicated that the established nomogram significantly outperformed the AJCC staging system (P

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Due to the deficiency of fresh water resources and the deterioration of groundwater quality worldwide, groundwater remedial technologies are especially crucial for preventing groundwater pollution and protecting the precious groundwater resource. Among the remedial alternatives, bioelectrochemical systems have unique advantages on both economic and technological aspects. However, it is rare to see a deep study focused on the information mining and visualization of the publications in this field, and research that can reveal and visualize the development trajectory and trends is scarce. Therefore, this study summarizes the published information in this field from the Web of Science Core Collection of the last two decades (1999−2018) and uses Citespace to quantitatively visualize the relationship of authors, published countries, organizations, funding sources, and journals and detect the research front by analyzing keywords and burst terms. The results indicate that the studies focused on bioelectrochemical systems for groundwater remediation have had a significant increase during the last two decades, especially in China, Germany and Italy. The national research institutes and universities of the USA and the countries mentioned above dominate the research. Environmental Science & Technology, Applied and Environmental Microbiology, and Water Research are the most published journals in this field. The network maps of the keywords and burst terms suggest that reductive microbial diversity, electron transfer, microbial fuel cell, etc., are the research hotspots in recent years, and studies focused on microbial enrichment culture, energy supply/recovery, combined pollution remediation, etc., should be enhanced in future.