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16 results on '"Xian, Quanxiang"'

3. Modulation of deep neural circuits with sonogenetics

Author

Xian, Quanxiang, primary, Qiu, Zhihai, additional, Murugappan, Suresh, additional, Kala, Shashwati, additional, Wong, Kin Fung, additional, Li, Danni, additional, Li, Guofeng, additional, Jiang, Yizhou, additional, Wu, Yong, additional, Su, Min, additional, Hou, Xuandi, additional, Zhu, Jiejun, additional, Guo, Jinghui, additional, Qiu, Weibao, additional, and Sun, Lei, additional

Published
2023
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4. The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation

Author

Zhu, Jiejun, primary, Xian, Quanxiang, additional, Hou, Xuandi, additional, Wong, Kin Fung, additional, Zhu, Tingting, additional, Chen, Zihao, additional, He, Dongming, additional, Kala, Shashwati, additional, Murugappan, Suresh, additional, Jing, Jianing, additional, Wu, Yong, additional, Zhao, Xinyi, additional, Li, Danni, additional, Guo, Jinghui, additional, Qiu, Zhihai, additional, and Sun, Lei, additional

Published
2023
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5. Sonogenetics: Recent advances and future directions

Author

Liu, Tianyi, primary, Choi, Mi Hyun, additional, Zhu, Jiejun, additional, Zhu, Tingting, additional, Yang, Jin, additional, Li, Na, additional, Chen, Zihao, additional, Xian, Quanxiang, additional, Hou, Xuandi, additional, He, Dongmin, additional, Guo, Jinghui, additional, Fei, Chunlong, additional, Sun, Lei, additional, and Qiu, Zhihai, additional

Published
2022
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6. Photonic Nanojet‐Mediated Optogenetics

Author

Guo, Jinghui, primary, Wu, Yong, additional, Gong, Zhiyong, additional, Chen, Xixi, additional, Cao, Fei, additional, Kala, Shashwati, additional, Qiu, Zhihai, additional, Zhao, Xinyi, additional, Chen, Jun‐jiang, additional, He, Dongming, additional, Chen, Taiheng, additional, Zeng, Rui, additional, Zhu, Jiejun, additional, Wong, Kin Fung, additional, Murugappan, Suresh, additional, Zhu, Ting, additional, Xian, Quanxiang, additional, Hou, Xuandi, additional, Ruan, Ye Chun, additional, Li, Baojun, additional, Li, Yu Chao, additional, Zhang, Yao, additional, and Sun, Lei, additional

Published
2022
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16. Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons.

Author

UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, Feng, Jia, Xian, Quanxiang, Guan, Tingting, Hu, Jing, Wang, Meizhi, Huang, Yuhua, So, Kwok-Fai, Evans, Sylvia M, Chai, Guoliang, Goffinet, André, Qu, Yibo, Zhou, Libing, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, Feng, Jia, Xian, Quanxiang, Guan, Tingting, Hu, Jing, Wang, Meizhi, Huang, Yuhua, So, Kwok-Fai, Evans, Sylvia M, Chai, Guoliang, Goffinet, André, Qu, Yibo, and Zhou, Libing

Abstract

Celsr3 and Fzd3 regulate the development of reciprocal thalamocortical projections independently of their expression in cortical or thalamic neurons. To understand this cell non autonomous mechanism further, we tested whether Celsr3 and Fzd3 could act via Isl1-positive guidepost cells. Isl1-positive cells appear in the forebrain at embryonic day (E) 9.5-E10.5 and, from E12.5, they form 2 contingents in ventral telencephalon and prethalamus. In control mice, corticothalamic axons run in the ventral telencephalic corridor in close contact with Isl1-positive cells. When Celsr3 or Fzd3 is inactivated in Isl1-expressing cells, corticofugal fibers stall and loop in the ventral telencephalic corridor of high Isl1 expression, and thalamic axons fail to cross the diencephalon-telencephalon junction (DTJ). At E12.5, before thalamic and cortical axons emerge, pioneer projections from Isl1-positive cells cross the DTJ from both sides in control but not mutant embryos. These early projections appear to act like a bridge to guide later growing thalamic axons through the DTJ. Our data suggest that Celsr3 and Fzd3 orchestrate the formation of a scaffold of pioneer neurons and their axons. This scaffold extends from prethalamus to ventral telencephalon and subcortex, and steers reciprocal corticothalamic fibers.

Published
2016

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