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154 results on '"Xercavins, Mariona"'

1. K-Means Clustering Identifies Diverse Clinical Phenotypes in COVID-19 Patients: Implications for Mortality Risks and Remdesivir Impact

Author

Garcia-Vidal, Carolina, Teijón-Lumbreras, Christian, Aiello, Tommaso Francesco, Chumbita, Mariana, Menendez, Rosario, Mateu-Subirà, Aina, Peyrony, Olivier, Monzó, Patricia, Lopera, Carlos, Gallardo-Pizarro, Antonio, Méndez, Raúl, Calbo, Esther, Xercavins, Mariona, Cuesta-Chasco, Genoveva, Martínez, José A., Marcos, Ma Angeles, Mensa, Josep, and Soriano, Alex

Published
2024
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2. Ceftaroline for bloodstream infections caused by methicillin-resistant Staphylococcus aureus: a multicentre retrospective cohort study

Author

Berbel, Damaris, Campany, David, Rio, Lara del, Eworo, Alia, Ferrando, Valeria, García-Tellado, Alex, Grau, Inmaculada, Guerra-Laso, José Manuel, Rodríguez, Sara, Roig-Sanchis, Joan, Sánchez-Martínez, Celia, Viñado, Belén, Urbina, Luciana, Halperin, Ana V., Xercavins, Mariona, Villa, Sofía de la, Escrihuela-Vidal, Francesc, Fernández-Hidalgo, Nuria, Escudero-Sánchez, Rosa, Cabezón, Itxasne, Boix-Palop, Lucía, Díaz-Pollán, Beatriz, Goikoetxea, Ane Josune, García-País, María José, Pérez-Rodríguez, María Teresa, Crespo, Ángela, Buzón-Martín, Luis, Sanz-Peláez, Oscar, Ramos-Merino, Lucía, Silvante, Fiorana, and Muñoz, Patricia

Published
2024
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4. Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Author

Sánchez, Fernando Fernández, de Lomas, José Mª García, Rosas, Gabriel, de la Torre Lima, Javier, Bereciartua, Elena, Vidal, María José Blanco, Blanco, Roberto, Boado, María Victoria, Lázaro, Marta Campaña, Crespo, Alejandro, Carrión, Laura Guio, Del Álamo Martínez de Lagos, Mikel, Ugarte, Gorane Euba, Goikoetxea, Ane Josune, Hierro, Marta Ibarrola, Iruretagoyena, José Ramón, Zuazabal, Josu Irurzun, López-Soria, Leire, Montejo, Miguel, Nieto, Javier, Rodrigo, David, Rodríguez, Regino, Vitoria, Yolanda, Voces, Roberto, López, Mª Victoria García, Georgieva, Radka Ivanova, Ojeda, Guillermo, Bailón, Isabel Rodríguez, Morales, Josefa Ruiz, Rodríguez, Ignacio Álvarez, Galparsoro, Harkaitz Azkune, Boronat, Elisa Berritu, Odriozola, Mª Jesús Bustinduy, del Bosque Martín, Cristina, Echeverría, Tomás, Yarza, Alberto Eizaguirre, Fuentes, Ana, Goenaga, Miguel Ángel, del Río, Muskilda Goyeneche, Bauza, Ángela Granda, Iribarren, José Antonio, Urkola, Xabier Kortajarena, López, José Ignacio Pérez-Moreiras, Jiménez, Ainhoa Rengel, Reviejo, Karlos, Berbejillo, Alberto Sáez, Haza, Elou Sánchez, Alda, Rosa Sebastián, Ruiz, Itziar Solla, Ugartemendia, Irati Unamuno, Anza, Diego Vicente, Benito, Iñaki Villanueva, Arrieta, Mar Zabalo, Carrasco, Rafael, Climent, Vicente, Llamas, Patricio, Merino, Esperanza, Plazas, Joaquín, Reus, Sergio, Bouzas, Alberto, Castelo, Brais, Cuenca, José, Gutiérrez, Laura, Ramos, Lucía, Mayo, María Rodríguez, Serrano, Joaquín Manuel, Regueiro, Dolores Sousa, Martínez, Francisco Javier, del Mar Alonso, Mª, Castro, Beatriz, Melian, Teresa Delgado, Sarabia, Javier Fernández, Rosado, Dácil García, González, Julia González, Lacalzada, Juan, de la Peña, Lissete Lorenzo, Ramírez, Alina Pérez, Arrondo, Pablo Prada, Moreno, Fermín Rodríguez, Ciezar, Antonio Plata, Iglesias, José Mª Reguera, Álvarez, Víctor Asensi, Costas, Carlos, de la Hera, Jesús, Suárez, Jonnathan Fernández, Fraile, Lisardo Iglesias, Arguero, Víctor León, Menéndez, José López, Bajo, Pilar Mencia, Morales, Carlos, Torrico, Alfonso Moreno, Palomo, Carmen, Martínez, Begoña Paya, Esteban, Ángeles Rodríguez, García, Raquel Rodríguez, Asensio, Mauricio Telenti, Almela, Manuel, Ambrosioni, Juan, Azqueta, Manuel, Brunet, Mercè, Bodro, Marta, Cartañá, Ramón, Cuervo, Guillermo, Falces, Carlos, Fernández-Pittol, Mariana J, Fita, Guillermina, Fuster, David, de la Mària, Cristina García, García-Pares, Delia, Hernández-Meneses, Marta, Pérez, Jaume Llopis, Marco, Francesc, Miró, José M., Moreno, Asunción, Nicolás, David, Ninot, Salvador, Quintana, Eduardo, Paré, Carlos, Pereda, Daniel, Pericás, Juan M., Pomar, José L., Ramírez, José, Roque, Mercè, Rovira, Irene, Sandoval, Elena, Sitges, Marta, Soy, Dolors, Téllez, Adrián, Tolosana, José M., Vidal, Bárbara, Vila, Jordi, Adán, Iván, Alonso, David, Alonso, Juan Carlos, Álvarez-Uría, Ana, Bermejo, Javier, Bouza, Emilio, Caballero, Gregorio Cuerpo, Montero, Antonia Delgado, Estévez, Agustín, Ribas, Ramón Fortuny, Gargallo, Esther, Leoni, Mª Eugenia García, Mansilla, Ana González, Moraga, Francisco Javier González, Ramallo, Víctor González, Hernández, Martha Kestler, Hualde, Amaia Mari, Machado, Marina, Marín, Mercedes, Martínez-Sellés, Manuel, Melero, Rosa, Muñoz, Patricia, Monzón, Diego, Olmedo, María, Pedraz, Álvaro, Pinilla, Blanca, Pinto, Ángel, Rincón, Cristina, Rodríguez-Abella, Hugo, Rodríguez-Créixems, Marta, Sánchez-Pérez, Eduardo, Segado, Antonio, Toledo, Neera, Valerio, Maricela, Vázquez, Pilar, Moreno, Eduardo Verde, de la Villa, Sofía, Antorrena, Isabel, Loeches, Belén, Moreno, Mar, Ramírez, Ulises, Bastón, Verónica Rial, Romero, María, Rosillo, Sandra, Balbín, Jesús Agüero, Fernández, Cristina Amado, Castillo, Carlos Armiñanzas, de las Revillas, Francisco Arnaiz, Belaustegui, Manuel Cobo, Fariñas, María Carmen, Fariñas-Álvarez, Concepción, Sampedro, Marta Fernández, García, Iván, Rico, Claudia González, Gutiérrez-Fernández, Laura, Gutiérrez-Cuadra, Manuel, Díez, José Gutiérrez, Pajarón, Marcos, Parra, José Antonio, Teira, Ramón, Zarauza, Jesús, Parra, Jorge Calderón, Cobo, Marta, Domínguez, Fernando, Pavía, Pablo García, Cruz, Ana Fernández, Ramos-Martínez, Antonio, Romero, Isabel Sánchez, Centella, Tomasa, Hermida, José Manuel, Moya, José Luis, Martín-Dávila, Pilar, Navas, Enrique, Oliva, Enrique, del Río, Alejandro, Stuart, Jorge Rodríguez-Roda, Ruiz, Soledad, Tenorio, Carmen Hidalgo, Sequera, Sergio, Delia, Manuel Almendro, Araji, Omar, Barquero, José Miguel, Jambrina, Román Calvo, de Cueto, Marina, Acebal, Juan Gálvez, Méndez, Irene, Morales, Isabel, López-Cortés, Luis Eduardo, de Alarcón, Arístides, Gutiérrez-Carretero, Encarnación, Lepe, José Antonio, López-Haldón, José, Luque-Márquez, Rafael, Marín, Guillermo, Ortiz-Carrellán, Antonio, Sánchez-Domínguez, Eladio, Alonso, Luis Javier, Azcárate, Pedro, Gutiérrez, José Manuel Azcona, Blanco, José Ramón, Armas, Estíbaliz Corral, García-Álvarez, Lara, Oteo, José Antonio, Membrilla, Antonio Barros, Iglesias, Antonino Ginel, Grillo, Sara, Petracca, Rubén Leta, López-Contreras, Joaquín, Martínez, María Alba Rivera, Álvarez, M., Fernández, A.L., Martínez, Amparo, Prieto, A., Regueiro, Benito, Tijeira, E., Vega, Marino, Quiñonero, Amaia Aguirre, Miñambres, Ángela Alonso, Arana, Juan Carlos Gainzarain, de Alaiza Ortega, Sara González, Rodríguez, Miguel Ángel Morán, Rodríguez, Anai Moreno, de Zárate, Zuriñe Ortiz, Zapirain, José Joaquín Portu, de Adana Arroniz, Ester Sáez, Sánchez, Daisy Carolina Sorto, Antonio, Sánchez-Porto, Alejandro, Úbeda Iglesias, Leal, José Mª Arribas, Vázquez, Elisa García, Torres, Alicia Hernández, Blázquez, Ana, de la Morena Valenzuela, Gonzalo, Alonso, Ángel, Aramburu, Javier, Calvo, Felicitas Elena, Tarabini-Castellani, Paola, Gálvez, Eva Heredero, Bellido, Carolina Maicas, Pau, José Largo, Sepúlveda, Mª Antonia, Sierra, Pilar Toledano, Iqbal-Mirza, Sadaf Zafar, Alcolea, Eva Cascales, Yañez, Ivan Keituqwa, Martínez, Julián Navarro, Ballesta, Ana Peláez, Escobar, Eduardo Moreno, Monje, Alejandro Peña, Cabrera, Valme Sánchez, García, David Vinuesa, Asenjo, María Arrizabalaga, Luna, Carmen Cifuentes, Morcillo, Juana Núñez, Seco, Mª Cruz Pérez, Gelabert, Aroa Villoslada, Guallar, Carmen Aured, Abad, Nuria Fernández, Mangas, Pilar García, Adell, Marta Matamala, Ruiz, Mª Pilar Palacián, Porres, Juan Carlos, Vidal, Begoña Alcaraz, Del Amor Espín, María Jesús, Buendía, Francisco, Sánchez, Roberto Jiménez, Mármol, Rosario, Martínez, Francisco, Meseguer, Antonio, Pérez, Beatriz, Risco, Leticia, Saura, Zoser, Silva, Vanina, Villmarín, Mª Belén, Blanco, Mª Ángels Ribas, de Gopegui Bordes, Enrique Ruiz, Bonet, Laura Vidal, Borràs, Miquel Vives, Munera, Mª Carmen Bellón, Garaizabal, Elena Escribano, Martínez, Antonia Tercero, Luque, Juan Carlos Segura, Badía, Cristina, Palop, Lucía Boix, Xercavins, Mariona, Ibars, Sónia, Bosch, Xerach, Nebreda, Eloy Gómez, Herrera, Ibalia Horcajada, Gallego, Irene Menduiña, Pulido, Imanol, Santiago, Héctor Marrero, de Miguel Martínez, Isabel, Álamo, Elena Pisos, Sánchez, Daniel San Román, Pérez, Jorge Boan, Blanco, Eva Mª Aguilar, González, Mercedes Catalán, Peiretti, María Angélica Corres, Esteve, Andrea Eixerés, Pérez, Laura Domínguez, de Cossío Tejido, Santiago, Román, Francisco Galván, Robles, José Antonio García, Medrano, Francisco López, Gude, Mª Jesús López, Miguel, Mª Ángeles Orellana, Pilkington, Patrick, Ostalaza, Yolanda Revilla, Morales, Juan Ruiz, Solís, Sebastián Ruiz, Collado, Ana Sabín, Fernández, Marcos Sánchez, Rallo, Javier Solera, Martín, Jorge Solís, Escrihuela-Vidal, Francesc, Carratalà, Jordi, Grau, Inmaculada, Ardanuy, Carmen, Berbel, Dámaris, Salado, José Carlos Sánchez, Alegre, Oriol, Majoral, Alejandro Ruiz, Sbraga, Fabrizio, Blasco, Arnau, Sánchez, Laura Gracia, Sánchez-Rodríguez, Iván, Aldamiz, Gonzalo, Álvarez, Beatriz, Palacios, Marina Bernal, Úbeda, Alfonso Cabello, Roblas, Ricardo Fernández, Hernández, Rafael, Martín, Victoria Andrea Hortigüela, Kallmeyer, Andrea, Kancev, Cristina Landaeta, Martín, Marta, Ruiz, Miguel Morante, Lobato, Miguel Ángel Navas, Pello, Ana María, Prieto, Laura, Mallebrera, Marta Tomás, Varela, Laura, de la Peña Triguero, Mireia, Cerón, Ruth Esther Figueroa, Gómez, Lara Ruiz, Ble, Mireia, Gallego, Juan Pablo Horcajada, Ginel, Antonio José, López, Inmaculada, Mas, Alexandra, Mestres, Antoni, Molina, Lluís, Serrat, Ramón, Ribas, Núria, Sánchez, Francisca, Silverio, Ana, Suárez, Marina, Sorlí, Luisa, Recasens, Lluís, Taurón, Manuel, Regueras, María Fernández, Vallejo, María Ángeles Mantecón, Rivera, José Ángel Pérez, Mata, Nuria Sánchez, Cano, Antonia Calvo, Olivares, Miguel Fajardo, Núñez, María Victoria Millán, Sanz, Agustín Muñoz, Herrera-Hidalgo, Laura, Alonso-Menchén, David, Luque-Marquez, Rafael, Fariñas, María Del Carmen, Miró, Jose Maria, Goenaga, Miguel Angel, Angulo-Lara, Basilio, and Boix-Palop, Lucia

Published
2023
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5. Expanding HIV clinical monitoring: the role of CD4, CD8, and CD4/CD8 ratio in predicting non-AIDS events

Author

Jarrín, Inma, Dalmau, David, Navarro, M. Luisa, González, M. Isabel, Garcia, Federico, Poveda, Eva, Iribarren, Jose Antonio, Gutiérrez, Félix, Rubio, Rafael, Vidal, Francesc, Berenguer, Juan, González, Juan, Muñoz-Fernández, M. Ángeles, Jarrín, Inmaculada, Moreno, Cristina, Rava, Marta, Izquierdo, Rebeca, Mauleón, Elba, Portilla, Joaquín, Portilla, Irene, Merino, Esperanza, García, Gema, Agea, Iván, Sánchez-Payá, José, Rodríguez, Juan Carlos, Giner, Livia, Reus, Sergio, Boix, Vicente, Torrus, Diego, Pérez, Verónica, Portilla, Julia, Gómez, Juan Luís, Hernández, Jehovana, Lirola, Ana López, García, Dácil, Díaz-Flores, Felicitas, Alonso, M. Mar, Pelazas, Ricardo, Alemán, M. Remedios, Asensi, Víctor, Rivas Carmenado, María Eugenia, Suarez-Zarracina, Tomás, Pulido, Federico, Bisbal, Otilia, Hernando, M. Asunción, Rial, David, de Lagarde, María, Arce, Octavio, Pinto, Adriana, Bermejo, Laura, Santacreu, Mireia, Navarro, Roser, Gonzalez, Candela, Aramburu, M. José, Camino, Xabier, Ángel von Wichmann, Miguel, Goenaga, Miguel Ángel, Bustinduy, M. Jesús, Azkune, Harkaitz, Ibarguren, Maialen, Kortajarena, Xabier, Álvarez-Rodriguez, Ignacio, Gil, Leire, Martínez, Lourdes, Robledano, Catalina, Masiá, Mar, Padilla, Sergio, Adsuar, Araceli, Pascual, Rafael, Fernández, Marta, Galiana, Antonio, García, José Alberto, Barber, Xavier, Agullo, Vanessa, Abellán, Javier Garcia, Pascual, Reyes, Telenti, Guillermo, Guillén, Lucia, Botella, Ángela, Muga, Roberto, Sanvisens, Arantza, Fuster, Daniel, Gutierrez, Isabel, López, Juan Carlos, Ramírez, Margarita, Padilla, Belén, Gijón, Paloma, Aldamiz-Echevarría, Teresa, Tejerina, Francisco, Diez, Cristina, Pérez, Leire, Fanciulli, Chiara, Corral, Saray, Martí, Anna, Peraire, Joaquín, Viladés, Consuelo, Vargas, Montserrat, Olona, Montserrat, Rull, Anna, Alba, Verónica, Yeregui, Elena, Masip, Jenifer, García-Pardo, Graciano, Bertomeu, Frederic Gómez, Espineira, Sonia, Montero, Marta, Cuéllar, Sandra, Blanes, Marino, Tasias, María, Calabuig, Eva, Salavert, Miguel, Fernández, Juan, Segarra, Inmaculada, González-García, Juan, Delgado, Ana, Arnalich, Francisco, Arribas, José Ramón, Bernardino, Jose Ignacio, Castro, Juan Miguel, Escosa, Luis, Herranz, Pedro, Hontañón, Victor, García-Bujalance, Silvia, García, Milagros, González-Baeza, Alicia, Martín-Carbonero, M. Luz, Mayoral, Mario, Mellado, M. Jose, Esteban, Rafael, Montejano, Rocío, Montes, M. Luisa, Moreno, Victoria, Pérez-Valero, Ignacio, Rodés, Berta, Rúa, Guadalupe, Sainz, Talía, Sendagorta, Elena, Valencia, Eulalia, Busca, Carmen, Cano, Joanna, Cardiñanos, Julen, de Miguel, Rosa, Blanco, Jose Ramón, Pérez-Martínez, Laura, Oteo, José Antonio, Ibarra, Valvanera, Metola, Luis, Sanz, Mercedes, Arazo, Piedad, Sampériz, Gloria, Martinez, Marina, Jaén, Angels, Sanmartí, Montse, Cairó, Mireia, Martinez-Lacasa, Javier, Velli, Pablo, Font, Roser, Xercavins, Mariona, Alonso, Noemí, Aiello, Francesco, Rivero, María, Piérola, Beatriz, Goikoetxea, Maider, Gracia, María, Ibero, Carlos, Moreno, Estela, Repáraz, Jesús, Navarro, Gemma, Garcia, Manel Cervantes, Isbert, Sonia Calzado, Vilasaro, Marta Navarro, Garcia, Belen Lopez, Santos, Ignacio de los, Santos, Alejandro de los, Sanz, Jesús, García-Fraile, Lucio, Martín, Enrique, Sánchez-Cerrillo, Ildefonso, Calvet, Marta, Barrios, Ana, Bautista, Azucena, Sáez, Carmen, Ciudad, Marianela, Gutiérrez, Ángela, Moreno, Santiago, Campo, Santos del, Casado, José Luis, Dronda, Fernando, Moreno, Ana, Pérez, M. Jesús, Serrano, Sergio, Vivancos, M<ce:sup loc='post">a</ce:sup> Jesús, Martínez-Sanz, Javier, Vallejo, Alejandro, Sanchez, Matilde, Pérez-Molina, Jose Antonio, Hermida, José Manuel, Bernal, Enrique, Alcaraz, Antonia, Bravo, Joaquín, Muñoz, Ángeles, Tomás, Cristina, Martínez, Mónica, Villalba, M. Carmen, García, Federico, Martínez, Clara, Hernández, José, Medina, Leopoldo Muñoz, Álvarez, Marta, Chueca, Natalia, Vinuesa, David, de Salazar, Adolfo, Fuentes, Ana, Guirao, Emilio, Viñuela, Laura, Ruiz-Sancho, Andrés, Anguita, Francisco, Del Romero, Jorge, Raposo, Montserrat, Rodríguez, Carmen, Puerta, Teresa, Carrió, Juan Carlos, Vera, Mar, Ballesteros, Juan, Ayerdi, Oskar, Baza, Begoña, Orviz, Eva, Antela, Antonio, Losada, Elena, Riera, Melchor, Peñaranda, María, Ribas, M. Angels, Campins, Antoni A., Garcia-Gazalla, Mercedes, Fanjul, Francisco J., Murillas, Javier, Homar, Francisco, Vilchez, Helem H., Martin, Luisa, Payeras, Antoni, Santos, Jesús, López, María, Gómez, Crisitina, Viciana, Isabel, Palacios, Rosario, López-Cortés, Luis Fernando, Espinosa, Nuria, Roca, Cristina, Llaves, Silvia, Tiraboschi, Juan Manuel, Imaz, Arkaitz, Silva, Ana Karina, Saumoy, María, Scévola, Sofía Catalina, Curran, Adrián, Falcó, Vicenç, Navarro, Jordi, Burgos, Joaquin, Suanzes, Paula, García, Jorge, Descalzo, Vicente, Álvarez, Patricia, Planas, Bibiana, Sanchiz, Marta, Rodríguez, Lucía, Olalla, Julián, Sánchez, M José, Pérez, Javier, Arco, Alfonso del, Torre, Javier de la, Prada, José Luis, Martínez, Onofre Juan, Martinez, Lorena, Vera, Francisco Jesús, García, Josefina, Alcaraz, Begoña, Sánchez Guirao, Antonio Jesús, Mena, Alvaro, Castro, Angeles, Pernas, Berta, Vázquez, Pilar, López, Soledad, Ibarra, Sofía, García, Guillermo, Mirena, Josu, Ferrero, Oscar Luis, López, Josefina, Cámara, M. Mar, Peña, Mireia de la, Lopez, Miriam, Lopez, Iñigo, Lombide, Itxaso, Polo, Victor, de Miguel, Joana, Galera, Carlos, Fernández, Marian, Albendin, Helena, Castillo, Antonia, Iborra, Asunción, Moreno, Antonio, Merlos, M. Angustias, Vidal, Asunción, Amador, Concha, Pasquau, Francisco, Gil, Concepcion, Algado, Jose Tomás, Suarez-García, Inés, Malmierca, Eduardo, González-Ruano, Patricia, Ruiz, M. Pilar, Pascual, José Francisco, Sáez, Elena, Balsalobre, Luz, López, M. Villa, Omar, Mohamed, Herrero, Carmen, Gómez, M. Amparo, Alberto de Zarraga, Miguel, Pérez, Desiré, Estrada, Vicente, Sanz, Nieves, Cabello, Noemí, García, Jorge Vergas, Núñez, Maria Jose, Sagastagoitia, Iñigo, Górgolas, Miguel, Cabello, Alfonso, Álvarez, Beatriz, Prieto, Laura, Carrillo, Irene, Sanz, José, Arranz, Alberto, Hernández, Cristina, Novella, María, Galindo, M. José, Ferrer, Ana, Román, Antonio Rivero, Ruíz, Inma, Juárez, Antonio Rivero, López, Pedro, Machuca, Isabel, Frias, Mario, Camacho, Ángela, Pérez, Ignacio, Corona, Diana, Cervero, Miguel, Torres, Rafael, Pineda, Juan Antonio, Rincón, Pilar, Macías, Juan, Real, Luis Miguel, Corma, Anais, Gonzalez-Serna, Alejandro, Pérez, Alexandre, Morano, Luis, Miralles, Celia, Ocampo, Antonio, Pousada, Guillermo, Patiño, Lucía, Dueñas, Carlos, Gutiérrez, Sara, Tapia, Elena, Novoa, Cristina, Egües, Xjoylin, Telleria, Pablo, Díaz-Álvarez, Jorge, Rosas Cancio-Suarez, Marta, Ron, Raquel, Iribarren, José Antonio, Ruiz Sancho, Andrés, Cabello, Noemi, and Serrano-Villar, Sergio

Published
2023
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6. The hidden side of infective endocarditis: Diagnostic and management of 500 consecutive cases in noncardiac surgery centers (2009–2018)

Author

Miró, Jose M., Ambrosioni, Juan, Hernández-Meneses, Marta, Téllez, Adrian, Pericàs, Juan M., Dahl, Anders, Moreno, Asuncion, Aguilar, Sergi, López, Alba, García de la Mària, Cristina, Cañas-Pacheco, María Alejandra, García-González, Javier, Almela, Manel, Zboromyrska, Yuliya, Casals, Climent, Morales, Francisco-Javier, Bosch, Jordi, Marco, Francesc, Vila, Jordi, Quintana, Eduard, Sandoval, Elena, Paré, Juan C., Falces, Carlos, Pereda, Daniel, Cartañá, Ramon, Ninot, Salvador, Azqueta, Manel, Sitges, Marta, Vidal, Barbara, Pomar, José L., Castella, Manuel, Tolosana, José M., Regueiro, Anders, Ortiz, José, Fita, Guillermina, Rovira, Irene, Perissinotti, Andrés, Fuster, David, Ramírez, Jose, Brunet, Mercè, Soy, Dolors, Castro, Pedro, Nicolás, David, Llopis, Jaume, Calzado, Sonia, Gasch, Oriol, Gomila-Grange, Aina, Pedrosa, Marc, Alguacil, Marina, Sanfeliu, Isabel, Guillaumet, Eva, Guillamon, Laura, Caresia, Ana Paula, Díaz, Emilio, Boix-Palop, Lucía, Dietl, Beatriz, Gisbert, Laura, Calbo, Esther, Xercavins, Mariona, Ibars, Sonia, Trenado, Josep, de los Ríos, Javier Díez, Reynaga, Esteban Alberto, Navarro, María, Montserrat, Silvia, Robles, Rocío, Cuquet, Jordi, Arrieta, Itziar, Costa, Núria, Martí, Carmina, Pulido, Ángeles, Ayats, Montserrat, Garro, Pau, Esquirol, Xavier, Bustamante, Marco A., Sanmartí, Montserrat, Cárdenas, Antonio, García, Gloria, Andrés, Marta, García, María Consuelo, Hanacsek, Carme Agustí, Dorca, Esther, Ortiz, María, Roca, Juan Manuel, Mollet, Fundació Sanitària, Tricas, José Maria, Maur, Elisabet, Romeo, Isabel, Vidal-Galve, Rosa, García, Xelo, Agustí, Carme, Tricas, José M., Díez de los Ríos, Javier, and Miró, José M.

Published
2023
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9. Prevalence of Colorectal Neoplasms Among Patients With Enterococcus faecalis Endocarditis in the GAMES Cohort (2008–2017)

Author

Sánchez, Fernando Fernández, Noureddine, Mariam, Rosas, Gabriel, Lima, Javier de la Torre, Blanco, Roberto, Boado, María Victoria, Lázaro, Marta Campaña, Crespo, Alejandro, Goikoetxea, Josune, Iruretagoyena, José Ramón, Zuazabal, Josu Irurzun, López-Soria, Leire, Montejo, Miguel, Nieto, Javier, Rodrigo, David, Rodríguez, Regino, Vitoria, Yolanda, Voces, Roberto, López, Ma Victoria García, Georgieva, Radka Ivanova, Ojeda, Guillermo, Bailón, Isabel Rodríguez, Morales, Josefa Ruiz, Cuende, Ana María, Echeverría, Tomás, Fuerte, Ana, Gaminde, Eduardo, Goenaga, Miguel Ángel, Idígoras, Pedro, Iribarren, José Antonio, Yarza, Alberto Izaguirre, Urkola, Xabier Kortajarena, Reviejo, Carlos, Carrasco, Rafael, Climent, Vicente, Llamas, Patricio, Merino, Esperanza, Plazas, Joaquín, Reus, Sergio, Álvarez, Nemesio, Bravo-Ferrer, José María, Castelo, Laura, Cuenca, José, Llinares, Pedro, Rey, Enrique Miguez, Mayo, María Rodríguez, Sánchez, Efrén, Regueiro, Dolores Sousa, Martínez, Francisco Javier, del Mar Alonso, Ma, Castro, Beatriz, Rosado, Dácil García, del Carmen Durán, Ma, Gómez, Ma Antonia Miguel, Lacalzada, Juan, Nassar, Ibrahim, Ciezar, Antonio Plata, Iglesias, José Ma Reguera, Álvarez, Víctor Asensi, Costas, Carlos, Hera, Jesús de la, Suárez, Jonnathan Fernández, Fraile, Lisardo Iglesias, Arguero, Víctor León, Menéndez, José López, Bajo, Pilar Mencia, Morales, Carlos, Torrico, Alfonso Moreno, Palomo, Carmen, Martínez, Begoña Paya, Esteban, Ángeles Rodríguez, García, Raquel Rodríguez, Asensio, Mauricio Telenti, Almela, Manuel, Ambrosioni, Juan, Azqueta, Manuel, Brunet, Mercè, Bodro, Marta, Cartañá, Ramón, Falces, Carlos, Fita, Guillermina, Fuster, David, García de la Mària, Cristina, García-Pares, Delia, Hernández-Meneses, Marta, Pérez, Jaume Llopis, Marco, Francesc, Miró, José M., Moreno, Asunción, Nicolás, David, Ninot, Salvador, Quintana, Eduardo, Paré, Carlos, Pereda, Daniel, Pericás, Juan M., Pomar, José L., Ramírez, José, Rovira, Irene, Sandoval, Elena, Sitges, Marta, Soy, Dolors, Téllez, Adrián, Tolosana, José M., Vidal, Bárbara, Vila, Jordi, Adán, Iván, Bermejo, Javier, Bouza, Emilio, Celemín, Daniel, Caballero, Gregorio Cuerpo, Montero, Antonia Delgado, Mansilla, Ana García, Leoni, Ma Eugenia García, Ramallo, Víctor González, Hernández, Martha Kestler, Hualde, Amaia Mari, Marín, Mercedes, Martínez-Sellés, Manuel, Muñoz, Patricia, Rincón, Cristina, Rodríguez-Abella, Hugo, Rodríguez-Créixems, Marta, Pinilla, Blanca, Pinto, Ángel, Valerio, Maricela, Vázquez, Pilar, Moreno, Eduardo Verde, Antorrena, Isabel, Loeches, Belén, Quirós, Alejandro Martín, Moreno, Mar, Ramírez, Ulises, Bastón, Verónica Rial, Romero, María, Saldaña, Araceli, Balbín, Jesús Agüero, Castillo, Carlos Armiñanzas, Arnaiz, Ana, de las Revillas, Francisco Arnaiz, Belaustegui, Manuel Cobo, Fariñas, María Carmen, Fariñas-Álvarez, Concepción, Izquierdo, Rubén Gómez, García, Iván, Rico, Claudia González, Gutiérrez-Cuadra, Manuel, Díez, José Gutiérrez, Pajarón, Marcos, Parra, José Antonio, Teira, Ramón, Zarauza, Jesús, Calderón Parra, Jorge, Cobo, Marta, Domínguez, Fernando, Fortaleza, Alberto, Pavía, Pablo García, González, Jesús, Cruz, Ana Fernández, Múñez, Elena, Ramos, Antonio, Romero, Isabel Sánchez, Centella, Tomasa, Hermida, José Manuel, Moya, José Luis, Martín-Dávila, Pilar, Navas, Enrique, Oliva, Enrique, Río, Alejandro del, Rodríguez-Roda Stuart, Jorge, Ruiz, Soledad, Tenorio, Carmen Hidalgo, Delia, Manuel Almendro, Araji, Omar, Barquero, José Miguel, Jambrina, Román Calvo, de Cueto, Marina, Acebal, Juan Gálvez, Méndez, Irene, Morales, Isabel, López-Cortés, Luis Eduardo, de Alarcón, Arístides, García, Emilio, Haro, Juan Luis, Lepe, José Antonio, López, Francisco, Luque, Rafael, Alonso, Luis Javier, Azcárate, Pedro, Azcona Gutiérrez, José Manuel, Blanco, José Ramón, Villegas, Antonio Cabrera, García-Álvarez, Lara, Oteo, José Antonio, Sanz, Mercedes, de Benito, Natividad, Gurguí, Mercé, Pacho, Cristina, Pericas, Roser, Pons, Guillem, Álvarez, M., Fernández, A.L., Martínez, Amparo, Prieto, A., Regueiro, Benito, Tijeira, E., Vega, Marino, Blasco, Andrés Canut, Mollar, José Cordo, Gainzarain Arana, Juan Carlos, Uriarte, Oscar García, López, Alejandro Martín, Ortiz de Zárate, Zuriñe, Urturi Matos, José Antonio, Gloria, García-Domínguez, Antonio, Sánchez-Porto, Leal, José Ma Arribas, Vázquez, Elisa García, Torres, Alicia Hernández, Blázquez, Ana, Valenzuela, Gonzalo de la Morena, Alonso, Ángel, Aramburu, Javier, Calvo, Felicitas Elena, Rodríguez, Anai Moreno, Tarabini-Castellani, Paola, Gálvez, Eva Heredero, Bellido, Carolina Maicas, Pau, José Largo, Sepúlveda, Ma Antonia, Sierra, Pilar Toledano, Iqbal-Mirza, Sadaf Zafar, Alcolea, Eva Cascales, Yañez, Ivan Keituqwa, Martínez, Julián Navarro, Ballesta, Ana Peláez, Escobar, Eduardo Moreno, Monje, Alejandro Peña, Cabrera, Valme Sánchez, García, David Vinuesa, Asenjo, María Arrizabalaga, Luna, Carmen Cifuentes, Morcillo, Juana Núñez, Seco, Ma Cruz Pérez, Gelabert, Aroa Villoslada, Guallar, Carmen Aured, Abad, Nuria Fernández, Mangas, Pilar García, Adell, Marta Matamala, Ruiz, Ma Pilar Palacián, Porres, Juan Carlos, Vidal, Begoña Alcaraz, Trigueros, Nazaret Cobos, Del Amor Espín, María Jesús, Giner Caro, José Antonio, Sánchez, Roberto Jiménez, Almazán, Amaya Jimeno, Freire, Alejandro Ortín, González, Monserrat Viqueira, Ramis, Pere Pericás, Blanco, Ma Ángels Ribas, Ruiz de Gopegui Bordes, Enrique, Bonet, Laura Vidal, Munera, Ma Carmen Bellón, Garaizabal, Elena Escribano, Martínez, Antonia Tercero, Segura Luque, Juan Carlos, Badía, Cristina, Palop, Lucía Boix, Xercavins, Mariona, Eloy Gómez Nebreda, Sónia Ibars., Herrera, Ibalia Horcajada, Gallego Héctor Marrero Santiago, Irene Menduiña, de Miguel Martínez, Isabel, Álamo, Elena Pisos, Pericàs, Juan M., Kestler, Martha, Mari-Hualde, Amaia, Goenaga, Miguel Á., Fariñas, M. Carmen, Rodríguez-Álvarez, Regino, Ojeda-Burgos, Guillermo, Gálvez-Acebal, Juan, and Hidalgo-Tenorio, Carmen

Published
2021
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11. Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Author

Herrera-Hidalgo, Laura, primary, Muñoz, Patricia, additional, Álvarez-Uría, Ana, additional, Alonso-Menchén, David, additional, Luque-Marquez, Rafael, additional, Gutiérrez-Carretero, Encarnación, additional, Fariñas, María Del Carmen, additional, Miró, Jose Maria, additional, Goenaga, Miguel Angel, additional, López-Cortés, Luis Eduardo, additional, Angulo-Lara, Basilio, additional, Boix-Palop, Lucia, additional, de Alarcón, Arístides, additional, Sánchez, Fernando Fernández, additional, de Lomas, José Mª García, additional, Rosas, Gabriel, additional, de la Torre Lima, Javier, additional, Bereciartua, Elena, additional, Vidal, María José Blanco, additional, Blanco, Roberto, additional, Boado, María Victoria, additional, Lázaro, Marta Campaña, additional, Crespo, Alejandro, additional, Carrión, Laura Guio, additional, Del Álamo Martínez de Lagos, Mikel, additional, Ugarte, Gorane Euba, additional, Goikoetxea, Ane Josune, additional, Hierro, Marta Ibarrola, additional, Iruretagoyena, José Ramón, additional, Zuazabal, Josu Irurzun, additional, López-Soria, Leire, additional, Montejo, Miguel, additional, Nieto, Javier, additional, Rodrigo, David, additional, Rodríguez, Regino, additional, Vitoria, Yolanda, additional, Voces, Roberto, additional, López, Mª Victoria García, additional, Georgieva, Radka Ivanova, additional, Ojeda, Guillermo, additional, Bailón, Isabel Rodríguez, additional, Morales, Josefa Ruiz, additional, Rodríguez, Ignacio Álvarez, additional, Galparsoro, Harkaitz Azkune, additional, Boronat, Elisa Berritu, additional, Odriozola, Mª Jesús Bustinduy, additional, del Bosque Martín, Cristina, additional, Echeverría, Tomás, additional, Yarza, Alberto Eizaguirre, additional, Fuentes, Ana, additional, Goenaga, Miguel Ángel, additional, del Río, Muskilda Goyeneche, additional, Bauza, Ángela Granda, additional, Iribarren, José Antonio, additional, Urkola, Xabier Kortajarena, additional, López, José Ignacio Pérez-Moreiras, additional, Jiménez, Ainhoa Rengel, additional, Reviejo, Karlos, additional, Berbejillo, Alberto Sáez, additional, Haza, Elou Sánchez, additional, Alda, Rosa Sebastián, additional, Ruiz, Itziar Solla, additional, Ugartemendia, Irati Unamuno, additional, Anza, Diego Vicente, additional, Benito, Iñaki Villanueva, additional, Arrieta, Mar Zabalo, additional, Carrasco, Rafael, additional, Climent, Vicente, additional, Llamas, Patricio, additional, Merino, Esperanza, additional, Plazas, Joaquín, additional, Reus, Sergio, additional, Bouzas, Alberto, additional, Castelo, Brais, additional, Cuenca, José, additional, Gutiérrez, Laura, additional, Ramos, Lucía, additional, Mayo, María Rodríguez, additional, Serrano, Joaquín Manuel, additional, Regueiro, Dolores Sousa, additional, Martínez, Francisco Javier, additional, del Mar Alonso, Mª, additional, Castro, Beatriz, additional, Melian, Teresa Delgado, additional, Sarabia, Javier Fernández, additional, Rosado, Dácil García, additional, González, Julia González, additional, Lacalzada, Juan, additional, de la Peña, Lissete Lorenzo, additional, Ramírez, Alina Pérez, additional, Arrondo, Pablo Prada, additional, Moreno, Fermín Rodríguez, additional, Ciezar, Antonio Plata, additional, Iglesias, José Mª Reguera, additional, Álvarez, Víctor Asensi, additional, Costas, Carlos, additional, de la Hera, Jesús, additional, Suárez, Jonnathan Fernández, additional, Fraile, Lisardo Iglesias, additional, Arguero, Víctor León, additional, Menéndez, José López, additional, Bajo, Pilar Mencia, additional, Morales, Carlos, additional, Torrico, Alfonso Moreno, additional, Palomo, Carmen, additional, Martínez, Begoña Paya, additional, Esteban, Ángeles Rodríguez, additional, García, Raquel Rodríguez, additional, Asensio, Mauricio Telenti, additional, Almela, Manuel, additional, Ambrosioni, Juan, additional, Azqueta, Manuel, additional, Brunet, Mercè, additional, Bodro, Marta, additional, Cartañá, Ramón, additional, Cuervo, Guillermo, additional, Falces, Carlos, additional, Fernández-Pittol, Mariana J, additional, Fita, Guillermina, additional, Fuster, David, additional, de la Mària, Cristina García, additional, García-Pares, Delia, additional, Hernández-Meneses, Marta, additional, Pérez, Jaume Llopis, additional, Marco, Francesc, additional, Miró, José M., additional, Moreno, Asunción, additional, Nicolás, David, additional, Ninot, Salvador, additional, Quintana, Eduardo, additional, Paré, Carlos, additional, Pereda, Daniel, additional, Pericás, Juan M., additional, Pomar, José L., additional, Ramírez, José, additional, Roque, Mercè, additional, Rovira, Irene, additional, Sandoval, Elena, additional, Sitges, Marta, additional, Soy, Dolors, additional, Téllez, Adrián, additional, Tolosana, José M., additional, Vidal, Bárbara, additional, Vila, Jordi, additional, Adán, Iván, additional, Alonso, David, additional, Alonso, Juan Carlos, additional, Bermejo, Javier, additional, Bouza, Emilio, additional, Caballero, Gregorio Cuerpo, additional, Montero, Antonia Delgado, additional, Estévez, Agustín, additional, Ribas, Ramón Fortuny, additional, Gargallo, Esther, additional, Leoni, Mª Eugenia García, additional, Mansilla, Ana González, additional, Moraga, Francisco Javier González, additional, Ramallo, Víctor González, additional, Hernández, Martha Kestler, additional, Hualde, Amaia Mari, additional, Machado, Marina, additional, Marín, Mercedes, additional, Martínez-Sellés, Manuel, additional, Melero, Rosa, additional, Monzón, Diego, additional, Olmedo, María, additional, Pedraz, Álvaro, additional, Pinilla, Blanca, additional, Pinto, Ángel, additional, Rincón, Cristina, additional, Rodríguez-Abella, Hugo, additional, Rodríguez-Créixems, Marta, additional, Sánchez-Pérez, Eduardo, additional, Segado, Antonio, additional, Toledo, Neera, additional, Valerio, Maricela, additional, Vázquez, Pilar, additional, Moreno, Eduardo Verde, additional, de la Villa, Sofía, additional, Antorrena, Isabel, additional, Loeches, Belén, additional, Moreno, Mar, additional, Ramírez, Ulises, additional, Bastón, Verónica Rial, additional, Romero, María, additional, Rosillo, Sandra, additional, Balbín, Jesús Agüero, additional, Fernández, Cristina Amado, additional, Castillo, Carlos Armiñanzas, additional, de las Revillas, Francisco Arnaiz, additional, Belaustegui, Manuel Cobo, additional, Fariñas, María Carmen, additional, Fariñas-Álvarez, Concepción, additional, Sampedro, Marta Fernández, additional, García, Iván, additional, Rico, Claudia González, additional, Gutiérrez-Fernández, Laura, additional, Gutiérrez-Cuadra, Manuel, additional, Díez, José Gutiérrez, additional, Pajarón, Marcos, additional, Parra, José Antonio, additional, Teira, Ramón, additional, Zarauza, Jesús, additional, Parra, Jorge Calderón, additional, Cobo, Marta, additional, Domínguez, Fernando, additional, Pavía, Pablo García, additional, Cruz, Ana Fernández, additional, Ramos-Martínez, Antonio, additional, Romero, Isabel Sánchez, additional, Centella, Tomasa, additional, Hermida, José Manuel, additional, Moya, José Luis, additional, Martín-Dávila, Pilar, additional, Navas, Enrique, additional, Oliva, Enrique, additional, del Río, Alejandro, additional, Stuart, Jorge Rodríguez-Roda, additional, Ruiz, Soledad, additional, Tenorio, Carmen Hidalgo, additional, Sequera, Sergio, additional, Delia, Manuel Almendro, additional, Araji, Omar, additional, Barquero, José Miguel, additional, Jambrina, Román Calvo, additional, de Cueto, Marina, additional, Acebal, Juan Gálvez, additional, Méndez, Irene, additional, Morales, Isabel, additional, Lepe, José Antonio, additional, López-Haldón, José, additional, Luque-Márquez, Rafael, additional, Marín, Guillermo, additional, Ortiz-Carrellán, Antonio, additional, Sánchez-Domínguez, Eladio, additional, Alonso, Luis Javier, additional, Azcárate, Pedro, additional, Gutiérrez, José Manuel Azcona, additional, Blanco, José Ramón, additional, Armas, Estíbaliz Corral, additional, García-Álvarez, Lara, additional, Oteo, José Antonio, additional, Membrilla, Antonio Barros, additional, Iglesias, Antonino Ginel, additional, Grillo, Sara, additional, Petracca, Rubén Leta, additional, López-Contreras, Joaquín, additional, Martínez, María Alba Rivera, additional, Álvarez, M., additional, Fernández, A.L., additional, Martínez, Amparo, additional, Prieto, A., additional, Regueiro, Benito, additional, Tijeira, E., additional, Vega, Marino, additional, Quiñonero, Amaia Aguirre, additional, Miñambres, Ángela Alonso, additional, Arana, Juan Carlos Gainzarain, additional, de Alaiza Ortega, Sara González, additional, Rodríguez, Miguel Ángel Morán, additional, Rodríguez, Anai Moreno, additional, de Zárate, Zuriñe Ortiz, additional, Zapirain, José Joaquín Portu, additional, de Adana Arroniz, Ester Sáez, additional, Sánchez, Daisy Carolina Sorto, additional, Antonio, Sánchez-Porto, additional, Alejandro, Úbeda Iglesias, additional, Leal, José Mª Arribas, additional, Vázquez, Elisa García, additional, Torres, Alicia Hernández, additional, Blázquez, Ana, additional, de la Morena Valenzuela, Gonzalo, additional, Alonso, Ángel, additional, Aramburu, Javier, additional, Calvo, Felicitas Elena, additional, Tarabini-Castellani, Paola, additional, Gálvez, Eva Heredero, additional, Bellido, Carolina Maicas, additional, Pau, José Largo, additional, Sepúlveda, Mª Antonia, additional, Sierra, Pilar Toledano, additional, Iqbal-Mirza, Sadaf Zafar, additional, Alcolea, Eva Cascales, additional, Yañez, Ivan Keituqwa, additional, Martínez, Julián Navarro, additional, Ballesta, Ana Peláez, additional, Escobar, Eduardo Moreno, additional, Monje, Alejandro Peña, additional, Cabrera, Valme Sánchez, additional, García, David Vinuesa, additional, Asenjo, María Arrizabalaga, additional, Luna, Carmen Cifuentes, additional, Morcillo, Juana Núñez, additional, Seco, Mª Cruz Pérez, additional, Gelabert, Aroa Villoslada, additional, Guallar, Carmen Aured, additional, Abad, Nuria Fernández, additional, Mangas, Pilar García, additional, Adell, Marta Matamala, additional, Ruiz, Mª Pilar Palacián, additional, Porres, Juan Carlos, additional, Vidal, Begoña Alcaraz, additional, Del Amor Espín, María Jesús, additional, Buendía, Francisco, additional, Sánchez, Roberto Jiménez, additional, Mármol, Rosario, additional, Martínez, Francisco, additional, Meseguer, Antonio, additional, Pérez, Beatriz, additional, Risco, Leticia, additional, Saura, Zoser, additional, Silva, Vanina, additional, Villmarín, Mª Belén, additional, Blanco, Mª Ángels Ribas, additional, de Gopegui Bordes, Enrique Ruiz, additional, Bonet, Laura Vidal, additional, Borràs, Miquel Vives, additional, Munera, Mª Carmen Bellón, additional, Garaizabal, Elena Escribano, additional, Martínez, Antonia Tercero, additional, Luque, Juan Carlos Segura, additional, Badía, Cristina, additional, Palop, Lucía Boix, additional, Xercavins, Mariona, additional, Ibars, Sónia, additional, Bosch, Xerach, additional, Nebreda, Eloy Gómez, additional, Herrera, Ibalia Horcajada, additional, Gallego, Irene Menduiña, additional, Pulido, Imanol, additional, Santiago, Héctor Marrero, additional, de Miguel Martínez, Isabel, additional, Álamo, Elena Pisos, additional, Sánchez, Daniel San Román, additional, Pérez, Jorge Boan, additional, Blanco, Eva Mª Aguilar, additional, González, Mercedes Catalán, additional, Peiretti, María Angélica Corres, additional, Esteve, Andrea Eixerés, additional, Pérez, Laura Domínguez, additional, de Cossío Tejido, Santiago, additional, Román, Francisco Galván, additional, Robles, José Antonio García, additional, Medrano, Francisco López, additional, Gude, Mª Jesús López, additional, Miguel, Mª Ángeles Orellana, additional, Pilkington, Patrick, additional, Ostalaza, Yolanda Revilla, additional, Morales, Juan Ruiz, additional, Solís, Sebastián Ruiz, additional, Collado, Ana Sabín, additional, Fernández, Marcos Sánchez, additional, Rallo, Javier Solera, additional, Martín, Jorge Solís, additional, Escrihuela-Vidal, Francesc, additional, Carratalà, Jordi, additional, Grau, Inmaculada, additional, Ardanuy, Carmen, additional, Berbel, Dámaris, additional, Salado, José Carlos Sánchez, additional, Alegre, Oriol, additional, Majoral, Alejandro Ruiz, additional, Sbraga, Fabrizio, additional, Blasco, Arnau, additional, Sánchez, Laura Gracia, additional, Sánchez-Rodríguez, Iván, additional, Aldamiz, Gonzalo, additional, Álvarez, Beatriz, additional, Palacios, Marina Bernal, additional, Úbeda, Alfonso Cabello, additional, Roblas, Ricardo Fernández, additional, Hernández, Rafael, additional, Martín, Victoria Andrea Hortigüela, additional, Kallmeyer, Andrea, additional, Kancev, Cristina Landaeta, additional, Martín, Marta, additional, Ruiz, Miguel Morante, additional, Lobato, Miguel Ángel Navas, additional, Pello, Ana María, additional, Prieto, Laura, additional, Mallebrera, Marta Tomás, additional, Varela, Laura, additional, de la Peña Triguero, Mireia, additional, Cerón, Ruth Esther Figueroa, additional, Gómez, Lara Ruiz, additional, Ble, Mireia, additional, Gallego, Juan Pablo Horcajada, additional, Ginel, Antonio José, additional, López, Inmaculada, additional, Mas, Alexandra, additional, Mestres, Antoni, additional, Molina, Lluís, additional, Serrat, Ramón, additional, Ribas, Núria, additional, Sánchez, Francisca, additional, Silverio, Ana, additional, Suárez, Marina, additional, Sorlí, Luisa, additional, Recasens, Lluís, additional, Taurón, Manuel, additional, Regueras, María Fernández, additional, Vallejo, María Ángeles Mantecón, additional, Rivera, José Ángel Pérez, additional, Mata, Nuria Sánchez, additional, Cano, Antonia Calvo, additional, Olivares, Miguel Fajardo, additional, Núñez, María Victoria Millán, additional, and Sanz, Agustín Muñoz, additional

Published
2023
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16. Expanding HIV clinical monitoring: the role of CD4, CD8, and CD4/CD8 ratio in predicting non-AIDS events

Author

Martínez-Sanz, Javier, primary, Díaz-Álvarez, Jorge, additional, Rosas Cancio-Suarez, Marta, additional, Ron, Raquel, additional, Iribarren, José Antonio, additional, Bernal, Enrique, additional, Gutiérrez, Félix, additional, Ruiz Sancho, Andrés, additional, Cabello, Noemi, additional, Olalla, Julián, additional, Moreno, Santiago, additional, Serrano-Villar, Sergio, additional, Jarrín, Inma, additional, Dalmau, David, additional, Navarro, M. Luisa, additional, González, M. Isabel, additional, Garcia, Federico, additional, Poveda, Eva, additional, Iribarren, Jose Antonio, additional, Rubio, Rafael, additional, Vidal, Francesc, additional, Berenguer, Juan, additional, González, Juan, additional, Muñoz-Fernández, M. Ángeles, additional, Jarrín, Inmaculada, additional, Moreno, Cristina, additional, Rava, Marta, additional, Izquierdo, Rebeca, additional, Mauleón, Elba, additional, Portilla, Joaquín, additional, Portilla, Irene, additional, Merino, Esperanza, additional, García, Gema, additional, Agea, Iván, additional, Sánchez-Payá, José, additional, Rodríguez, Juan Carlos, additional, Giner, Livia, additional, Reus, Sergio, additional, Boix, Vicente, additional, Torrus, Diego, additional, Pérez, Verónica, additional, Portilla, Julia, additional, Gómez, Juan Luís, additional, Hernández, Jehovana, additional, Lirola, Ana López, additional, García, Dácil, additional, Díaz-Flores, Felicitas, additional, Alonso, M. Mar, additional, Pelazas, Ricardo, additional, Alemán, M. Remedios, additional, Asensi, Víctor, additional, Rivas Carmenado, María Eugenia, additional, Suarez-Zarracina, Tomás, additional, Pulido, Federico, additional, Bisbal, Otilia, additional, Hernando, M. Asunción, additional, Rial, David, additional, de Lagarde, María, additional, Arce, Octavio, additional, Pinto, Adriana, additional, Bermejo, Laura, additional, Santacreu, Mireia, additional, Navarro, Roser, additional, Gonzalez, Candela, additional, Aramburu, M. José, additional, Camino, Xabier, additional, Ángel von Wichmann, Miguel, additional, Goenaga, Miguel Ángel, additional, Bustinduy, M. Jesús, additional, Azkune, Harkaitz, additional, Ibarguren, Maialen, additional, Kortajarena, Xabier, additional, Álvarez-Rodriguez, Ignacio, additional, Gil, Leire, additional, Martínez, Lourdes, additional, Robledano, Catalina, additional, Masiá, Mar, additional, Padilla, Sergio, additional, Adsuar, Araceli, additional, Pascual, Rafael, additional, Fernández, Marta, additional, Galiana, Antonio, additional, García, José Alberto, additional, Barber, Xavier, additional, Agullo, Vanessa, additional, Abellán, Javier Garcia, additional, Pascual, Reyes, additional, Telenti, Guillermo, additional, Guillén, Lucia, additional, Botella, Ángela, additional, Muga, Roberto, additional, Sanvisens, Arantza, additional, Fuster, Daniel, additional, Gutierrez, Isabel, additional, López, Juan Carlos, additional, Ramírez, Margarita, additional, Padilla, Belén, additional, Gijón, Paloma, additional, Aldamiz-Echevarría, Teresa, additional, Tejerina, Francisco, additional, Diez, Cristina, additional, Pérez, Leire, additional, Fanciulli, Chiara, additional, Corral, Saray, additional, Martí, Anna, additional, Peraire, Joaquín, additional, Viladés, Consuelo, additional, Vargas, Montserrat, additional, Olona, Montserrat, additional, Rull, Anna, additional, Alba, Verónica, additional, Yeregui, Elena, additional, Masip, Jenifer, additional, García-Pardo, Graciano, additional, Bertomeu, Frederic Gómez, additional, Espineira, Sonia, additional, Montero, Marta, additional, Cuéllar, Sandra, additional, Blanes, Marino, additional, Tasias, María, additional, Calabuig, Eva, additional, Salavert, Miguel, additional, Fernández, Juan, additional, Segarra, Inmaculada, additional, González-García, Juan, additional, Delgado, Ana, additional, Arnalich, Francisco, additional, Arribas, José Ramón, additional, Bernardino, Jose Ignacio, additional, Castro, Juan Miguel, additional, Escosa, Luis, additional, Herranz, Pedro, additional, Hontañón, Victor, additional, García-Bujalance, Silvia, additional, García, Milagros, additional, González-Baeza, Alicia, additional, Martín-Carbonero, M. Luz, additional, Mayoral, Mario, additional, Mellado, M. Jose, additional, Esteban, Rafael, additional, Montejano, Rocío, additional, Montes, M. Luisa, additional, Moreno, Victoria, additional, Pérez-Valero, Ignacio, additional, Rodés, Berta, additional, Rúa, Guadalupe, additional, Sainz, Talía, additional, Sendagorta, Elena, additional, Valencia, Eulalia, additional, Busca, Carmen, additional, Cano, Joanna, additional, Cardiñanos, Julen, additional, de Miguel, Rosa, additional, Blanco, Jose Ramón, additional, Pérez-Martínez, Laura, additional, Oteo, José Antonio, additional, Ibarra, Valvanera, additional, Metola, Luis, additional, Sanz, Mercedes, additional, Arazo, Piedad, additional, Sampériz, Gloria, additional, Martinez, Marina, additional, Jaén, Angels, additional, Sanmartí, Montse, additional, Cairó, Mireia, additional, Martinez-Lacasa, Javier, additional, Velli, Pablo, additional, Font, Roser, additional, Xercavins, Mariona, additional, Alonso, Noemí, additional, Aiello, Francesco, additional, Rivero, María, additional, Piérola, Beatriz, additional, Goikoetxea, Maider, additional, Gracia, María, additional, Ibero, Carlos, additional, Moreno, Estela, additional, Repáraz, Jesús, additional, Navarro, Gemma, additional, Garcia, Manel Cervantes, additional, Isbert, Sonia Calzado, additional, Vilasaro, Marta Navarro, additional, Garcia, Belen Lopez, additional, Santos, Ignacio de los, additional, Santos, Alejandro de los, additional, Sanz, Jesús, additional, García-Fraile, Lucio, additional, Martín, Enrique, additional, Sánchez-Cerrillo, Ildefonso, additional, Calvet, Marta, additional, Barrios, Ana, additional, Bautista, Azucena, additional, Sáez, Carmen, additional, Ciudad, Marianela, additional, Gutiérrez, Ángela, additional, Campo, Santos del, additional, Casado, José Luis, additional, Dronda, Fernando, additional, Moreno, Ana, additional, Pérez, M. Jesús, additional, Serrano, Sergio, additional, Vivancos, Ma Jesús, additional, Martínez-Sanz, Javier, additional, Vallejo, Alejandro, additional, Sanchez, Matilde, additional, Pérez-Molina, Jose Antonio, additional, Hermida, José Manuel, additional, Alcaraz, Antonia, additional, Bravo, Joaquín, additional, Muñoz, Ángeles, additional, Tomás, Cristina, additional, Martínez, Mónica, additional, Villalba, M. Carmen, additional, García, Federico, additional, Martínez, Clara, additional, Hernández, José, additional, Medina, Leopoldo Muñoz, additional, Álvarez, Marta, additional, Chueca, Natalia, additional, Vinuesa, David, additional, de Salazar, Adolfo, additional, Fuentes, Ana, additional, Guirao, Emilio, additional, Viñuela, Laura, additional, Ruiz-Sancho, Andrés, additional, Anguita, Francisco, additional, Del Romero, Jorge, additional, Raposo, Montserrat, additional, Rodríguez, Carmen, additional, Puerta, Teresa, additional, Carrió, Juan Carlos, additional, Vera, Mar, additional, Ballesteros, Juan, additional, Ayerdi, Oskar, additional, Baza, Begoña, additional, Orviz, Eva, additional, Antela, Antonio, additional, Losada, Elena, additional, Riera, Melchor, additional, Peñaranda, María, additional, Ribas, M. Angels, additional, Campins, Antoni A., additional, Garcia-Gazalla, Mercedes, additional, Fanjul, Francisco J., additional, Murillas, Javier, additional, Homar, Francisco, additional, Vilchez, Helem H., additional, Martin, Luisa, additional, Payeras, Antoni, additional, Santos, Jesús, additional, López, María, additional, Gómez, Crisitina, additional, Viciana, Isabel, additional, Palacios, Rosario, additional, López-Cortés, Luis Fernando, additional, Espinosa, Nuria, additional, Roca, Cristina, additional, Llaves, Silvia, additional, Tiraboschi, Juan Manuel, additional, Imaz, Arkaitz, additional, Silva, Ana Karina, additional, Saumoy, María, additional, Scévola, Sofía Catalina, additional, Curran, Adrián, additional, Falcó, Vicenç, additional, Navarro, Jordi, additional, Burgos, Joaquin, additional, Suanzes, Paula, additional, García, Jorge, additional, Descalzo, Vicente, additional, Álvarez, Patricia, additional, Planas, Bibiana, additional, Sanchiz, Marta, additional, Rodríguez, Lucía, additional, Sánchez, M José, additional, Pérez, Javier, additional, Arco, Alfonso del, additional, Torre, Javier de la, additional, Prada, José Luis, additional, Martínez, Onofre Juan, additional, Martinez, Lorena, additional, Vera, Francisco Jesús, additional, García, Josefina, additional, Alcaraz, Begoña, additional, Sánchez Guirao, Antonio Jesús, additional, Mena, Alvaro, additional, Castro, Angeles, additional, Pernas, Berta, additional, Vázquez, Pilar, additional, López, Soledad, additional, Ibarra, Sofía, additional, García, Guillermo, additional, Mirena, Josu, additional, Ferrero, Oscar Luis, additional, López, Josefina, additional, Cámara, M. Mar, additional, Peña, Mireia de la, additional, Lopez, Miriam, additional, Lopez, Iñigo, additional, Lombide, Itxaso, additional, Polo, Victor, additional, de Miguel, Joana, additional, Galera, Carlos, additional, Fernández, Marian, additional, Albendin, Helena, additional, Castillo, Antonia, additional, Iborra, Asunción, additional, Moreno, Antonio, additional, Merlos, M. Angustias, additional, Vidal, Asunción, additional, Amador, Concha, additional, Pasquau, Francisco, additional, Gil, Concepcion, additional, Algado, Jose Tomás, additional, Suarez-García, Inés, additional, Malmierca, Eduardo, additional, González-Ruano, Patricia, additional, Ruiz, M. Pilar, additional, Pascual, José Francisco, additional, Sáez, Elena, additional, Balsalobre, Luz, additional, López, M. Villa, additional, Omar, Mohamed, additional, Herrero, Carmen, additional, Gómez, M. Amparo, additional, Alberto de Zarraga, Miguel, additional, Pérez, Desiré, additional, Estrada, Vicente, additional, Sanz, Nieves, additional, Cabello, Noemí, additional, García, Jorge Vergas, additional, Núñez, Maria Jose, additional, Sagastagoitia, Iñigo, additional, Górgolas, Miguel, additional, Cabello, Alfonso, additional, Álvarez, Beatriz, additional, Prieto, Laura, additional, Carrillo, Irene, additional, Sanz, José, additional, Arranz, Alberto, additional, Hernández, Cristina, additional, Novella, María, additional, Galindo, M. José, additional, Ferrer, Ana, additional, Román, Antonio Rivero, additional, Ruíz, Inma, additional, Juárez, Antonio Rivero, additional, López, Pedro, additional, Machuca, Isabel, additional, Frias, Mario, additional, Camacho, Ángela, additional, Pérez, Ignacio, additional, Corona, Diana, additional, Cervero, Miguel, additional, Torres, Rafael, additional, Pineda, Juan Antonio, additional, Rincón, Pilar, additional, Macías, Juan, additional, Real, Luis Miguel, additional, Corma, Anais, additional, Gonzalez-Serna, Alejandro, additional, Pérez, Alexandre, additional, Morano, Luis, additional, Miralles, Celia, additional, Ocampo, Antonio, additional, Pousada, Guillermo, additional, Patiño, Lucía, additional, Dueñas, Carlos, additional, Gutiérrez, Sara, additional, Tapia, Elena, additional, Novoa, Cristina, additional, Egües, Xjoylin, additional, and Telleria, Pablo, additional

Published
2023
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17. The hidden side of infective endocarditis: Diagnostic and management of 500 consecutive cases in noncardiac surgery centers (2009–2018)

Author

Calzado, Sonia, primary, Hernández-Meneses, Marta, additional, Llopis, Jaume, additional, Boix-Palop, Lucía, additional, Dietl, Beatriz, additional, Calbo, Esther, additional, Andrés, Marta, additional, García, Xelo, additional, Agustí, Carme, additional, Dorca, Esther, additional, Tricas, José M., additional, Díez de los Ríos, Javier, additional, Cuquet, Jordi, additional, Cárdenas, Antonio, additional, Roca, Juan Manuel, additional, Ortiz, María, additional, Caresia, Ana Paula, additional, Guillamon, Laura, additional, Quintana, Eduard, additional, Ambrosioni, Juan, additional, Gasch, Oriol, additional, Miró, José M., additional, Miró, Jose M., additional, Téllez, Adrian, additional, Pericàs, Juan M., additional, Dahl, Anders, additional, Moreno, Asuncion, additional, Aguilar, Sergi, additional, López, Alba, additional, García de la Mària, Cristina, additional, Cañas-Pacheco, María Alejandra, additional, García-González, Javier, additional, Almela, Manel, additional, Zboromyrska, Yuliya, additional, Casals, Climent, additional, Morales, Francisco-Javier, additional, Bosch, Jordi, additional, Marco, Francesc, additional, Vila, Jordi, additional, Sandoval, Elena, additional, Paré, Juan C., additional, Falces, Carlos, additional, Pereda, Daniel, additional, Cartañá, Ramon, additional, Ninot, Salvador, additional, Azqueta, Manel, additional, Sitges, Marta, additional, Vidal, Barbara, additional, Pomar, José L., additional, Castella, Manuel, additional, Tolosana, José M., additional, Regueiro, Anders, additional, Ortiz, José, additional, Fita, Guillermina, additional, Rovira, Irene, additional, Perissinotti, Andrés, additional, Fuster, David, additional, Ramírez, Jose, additional, Brunet, Mercè, additional, Soy, Dolors, additional, Castro, Pedro, additional, Nicolás, David, additional, Calzado, Sonia, additional, Gomila-Grange, Aina, additional, Pedrosa, Marc, additional, Alguacil, Marina, additional, Sanfeliu, Isabel, additional, Guillaumet, Eva, additional, Díaz, Emilio, additional, Gisbert, Laura, additional, Xercavins, Mariona, additional, Ibars, Sonia, additional, Trenado, Josep, additional, de los Ríos, Javier Díez, additional, Reynaga, Esteban Alberto, additional, Navarro, María, additional, Montserrat, Silvia, additional, Robles, Rocío, additional, Arrieta, Itziar, additional, Costa, Núria, additional, Martí, Carmina, additional, Pulido, Ángeles, additional, Ayats, Montserrat, additional, Garro, Pau, additional, Esquirol, Xavier, additional, Bustamante, Marco A., additional, Sanmartí, Montserrat, additional, García, Gloria, additional, García, María Consuelo, additional, Hanacsek, Carme Agustí, additional, Mollet, Fundació Sanitària, additional, Tricas, José Maria, additional, Maur, Elisabet, additional, Romeo, Isabel, additional, and Vidal-Galve, Rosa, additional

Published
2023
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18. Significant increase of CTX-M-15-ST131 and emergence of CTX-M-27-ST131 Escherichia coli high-risk clones causing healthcare-associated bacteraemia of urinary origin in Spain (ITUBRAS-2 project)

Author

Becerra-Aparicio, Federico, primary, Gómez-Zorrilla, Silvia, additional, Hernández-García, Marta, additional, Gijón, Desiré, additional, Siverio, Ana, additional, Berbel, Dàmaris, additional, Sánchez-Carrillo, Carlos, additional, Cercenado, Emilia, additional, Rivera, Alba, additional, de Malet, Ana, additional, Xercavins, Mariona, additional, Ruiz de Gopegui, Enrique, additional, Canoura-Fernández, Luis, additional, Martínez, José Antonio, additional, Seral, Cristina, additional, Del Pozo, José Luis, additional, Cotarelo, Manuel, additional, Díaz-Regañón, Jazmín, additional, Cantón, Rafael, additional, Oliver, Antonio, additional, Horcajada, Juan Pablo, additional, and Ruiz-Garbajosa, Patricia, additional

Published
2023
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24. Risk of cardiac device-related infection in patients with late-onset bloodstream infection. Analysis on a National Cohort

Author

Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades (España), Red Española de Investigación en Patología Infecciosa, European Commission, Boix-Palop, Lucía, Dietl, Beatriz, Calbo, Esther, Di Marco, Andrea, Xercavins, Mariona, Martínez Pérez-Crespo, Pedro María, Sousa, Adrián, Montejo, Miguel, Rodríguez-Baño, Jesús, López-Cortés, Luis Eduardo, Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades (España), Red Española de Investigación en Patología Infecciosa, European Commission, Boix-Palop, Lucía, Dietl, Beatriz, Calbo, Esther, Di Marco, Andrea, Xercavins, Mariona, Martínez Pérez-Crespo, Pedro María, Sousa, Adrián, Montejo, Miguel, Rodríguez-Baño, Jesús, and López-Cortés, Luis Eduardo

Abstract

[Objectives] To determine the incidence of cardiac device-related infection (CDRI) among patients with cardiac device (CD) during late-onset bloodstream infection (BSI) and to identify the risk factors associated with CDRI., [Methods] Patients with a CD (cardiac implantable electronic devices -CIED- and/or prosthetic heart valve -PHV-) and late-onset-BSI (>1 year after the CD implantation/last manipulation) were selected from the PROBAC project, a prospective, observational cohort study including adult patients with bacteraemia consecutively admitted to 26 Spanish hospitals from October 2016 to March 2017. Multivariate analyses using logistic regression were performed to identify the risk factors associated with CDRI., [Results] 317 BSI from patients carrying a CD were registered, 187 (56.2%) were late-onset-BSI. A total of 40 (21.4%) CDRI were identified during late-onset-BSI. The CDRI cumulative incidence in Gram-positive-BSI was 41.8% (38/91), with S. aureus, Enterococcus spp. and viridans streptococci showing the greatest percentages: 40% (12/30), 42% (11/26) and 75% (6/8), respectively. Independent predictors of CDRI were an unknown source of infection (OR: 2.88 [CI 95%:1.18–7.06], p = 0.02), Gram-positive-aetiology (23.1 [5.23–102.1], p < 0.001) and persistent bacteraemia (4.81 [1.21–19], p = 0.03). In an exploratory analysis, S. aureus (3.99 [1.37–11.65], p = 0.011), Enterococcus spp. (5.21 [1.76–15.4], p = 0.003) and viridans streptococci (28.7 [4.71–173.5], p < 0.001) aetiology were also found to be risk factors for CDRI., [Conclusions] CDRI during late-onset-BSI is a frequent phenomenon. Risk of CDRI differs among species, happening in almost half of the Gram-positive-BSI. An unknown source of the primary infection, Gram-positive-aetiology -especially S. aureus, Enterococcus spp. and viridans streptococci-, and persistent bacteraemia were identified as risk factors for CDRI.

Published
2022

27. Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections

Author

Sojo Dorado, Jesús, López Hernández, Inmaculada, Rosso Fernández, Clara, Morales, Isabel M., Palacios Baena, Zaira R., Hernández Torres, Alicia, Merino de Lucas, Esperanza, Escolà Vergé, Laura, Bereciartua, Elena, García Vázquez, Elisa, Pintado, Vicente, Boix Palop, Lucía, Natera Kindelán, Clara, Sorlí, Luisa, Borrell, Nuria, Giner Oncina, Livia, Amador Prous, Concha, Shaw, Evelyn, Jover Saenz, Alfredo, Molina, Jose, Martínez Álvarez, Rosa M., Dueñas, Carlos J., Calvo Montes, Jorge, Silva, Jose T., Cárdenes, Miguel A., Lecuona, María, Pomar, Virginia, Valiente de Santis, Lucía, Yagüe Guirao, Genoveva, Lobo Acosta, María Angeles, Merino Bohórquez, Vicente, Pascual, Alvaro, Rodríguez Baño, Jesús, Almirante, Benito, Fernández, Mario, Paño Pardo, José Ramón, Cueto, Marina de, Retamar Gentil, Pilar, López Cortés, Luis Eduardo, Gutiérrez Gutiérrez, Belén, Docobo, Fernando, Borreguero, Irene, Camean, Manuel, Moral Escudero, Encarnación, Pareja Rodríguez de Vera, Ana, Martínez Toldos, María del Carmen, Blázquez Abellán, Ana, Belles Belles, Alba, Ramírez Hidalgo, María Fernanda, Mirelis, Beatriz, Calbo, Esther, Xercavins, Mariona, Gracia Ahufinger, Irene, Cano Yuste, Angela M., Guío, Laura, Hernandez, Jose Luis, Pigrau Serrallach, Carlos, Viñado Pérez, Belen, Puig Asensio, Mireia, Ardanuy, Carmen, Pujol, Miquel, García Rosado, Dácil, Gil Anguita, Concepción, Siverio, Ana, Gimeno Gascón, Adelina, Boix Martínez, Vicente, Reus Bañuls, Sergio, Agea Durán, Iván, Fariñas, Carmen, Palop, Begoña, Vilchez, Helem, Lepe, José Antonio, Gil Navarro, María Victoria, San Juan, Rafael, Chaves, Fernando, Escudero, Rosa, Gioia, Francesca, Sánchez Díaz, Ana María, Cañas Pedrosa, Ana, Sangil Monroy, Nayra, Toyas Miazza, Carla, and Reipi Geiras Forest Group

Subjects
Escheríchia coli, Infeccions del tracte urinari, Escherichia coli, Urinary tract infections
Abstract

IMPORTANCE The consumption of broad-spectrum drugs has increased as a consequence of the spread of multidrug-resistant (MDR) Escherichia coli. Finding alternatives for these infections is critical, for which some neglected drugs may be an option. OBJECTIVE To determine whether fosfomycin is noninferior to ceftriaxone or meropenem in the targeted treatment of bacteremic urinary tract infections (bUTIs) due to MDR E coli. DESIGN, SETTING, AND PARTICIPANTS This multicenter, randomized, pragmatic, open clinical trial was conducted at 22 Spanish hospitals from June 2014 to December 2018. Eligible participants were adult patients with bacteremic urinary tract infections due to MDR E coli; 161 of 1578 screened patients were randomized and followed up for 60 days. Data were analyzed in May 2021. INTERVENTIONS Patients were randomized 1 to 1 to receive intravenous fosfomycin disodium at 4 g every 6 hours (70 participants) or a comparator (ceftriaxone or meropenem if resistant; 73 participants) with the option to switch to oral fosfomycin trometamol for the fosfomycin group or an active oral drug or pa renteral ertapenem for the comparator group after 4 days. MAIN OUTCOMES AND MEASURES The primary outcome was clinical and microbiological cure (CMC) 5 to 7 days after finalization of treatment; a noninferiority margin of 7% was considered. RESULTS Among 143 patients in the modified intention-to-treat population (median [IQR] age, 72 [62-81] years; 73 [51.0%] women), 48 of 70 patients (68.6%) treated with fosfomycin and 57 of 73 patients (78.1%) treated with comparators reached CMC (risk difference, -9.4 percentage points; 1-sided 95% CI, -21.5 to infinity percentage points; P = .10). While clinical or microbiological failure occurred among 10 patients (14.3%) treated with fosfomycin and 14 patients (19.7%) treated with comparators (risk difference, -5.4 percentage points; 1-sided 95% CI. -infinity to 4.9; percentage points; P = .19), an increased rate of adverse event-related discontinuations occurred with fosfomycin vs comparators (6 discontinuations [8.5%] vs 0 discontinuations; P = .006). In an exploratory analysis among a subset of 38 patients who underwent rectal colonization studies, patients treated with fosfomycin acquired a new ceftriaxone-resistant or meropenem-resistant gram-negative bacteria at a decreased rate compared with patients treated with comparators (0 of 21 patients vs 4 of 17 patients [23.5%]; 1-sided P = .01). CONCLUSIONS AND RELEVANCE This study found that fosfomycin did not demonstrate noninferiority to comparators as targeted treatment of bUTI from MDR E coli; this was due to an increased rate of adverse event-related discontinuations. This finding suggests that fosfomycin may be considered for selected patients with these infections.

Published
2022

29. Mural Endocarditis: The GAMES Registry Series and Review of the Literature

Author

Gutiérrez-Villanueva, Andrea, Muñoz, Patricia, Delgado-Montero, Antonia, Olmedo-Samperio, María, de Alarcón, Arístides, Gutiérrez-Carretero, Encarnación, Zarauza, Jesús, García i Pares, Delia, Goenaga, Miguel Ángel, Ojeda-Burgos, Guillermo, Goikoetxea-Agirre, Ane Josune, Reguera-Iglesias, José Mª, Ramos, Antonio, Fernández-Cruz, Ana, Fernández-Sánchez, Fernando, García de Lomas, José Mª, Rosas, Gabriel, de la Torre Lima, Javier, Bereciartua, Elena, Blanco-Vidal, María José, Blanco, Roberto, Boado, María Victoria, Campaña-Lázaro, Marta, Crespo, Alejandro, Guio-Carrión, Laura, del Álamo Martínez-Lagos, Mikel, Euba-Ugarte, Gorane, Goikoetxea, Ane Josune, Ibarrola-Hierro, Marta, Iruretagoyena, José Ramón, Irurzun-Zuazabal, Josu, López-Soria, Leire, Montejo, Miguel, Nieto, Javier, Rodrigo, David, Rodríguez, Regino, Vitoria, Yolanda, Voces, Roberto, García-López, Mª Victoria, Georgieva, Radka Ivanova, Ojeda, Guillermo, Rodríguez-Bailón, Isabel, Ruiz-Morales, Josefa, Azkune-Galparsoro, Harkaitz, Berritu-Boronat, Elisa, Bustinduy-Odriozola, Mª Jesús, del Bosque Martín, Cristina, Echeverría, Tomás, Eizaguirre-Yarza, Alberto, Fuentes, Ana, Goyeneche del Río, Muskilda, Granda-Bauza, Ángela, Iribarren, José Antonio, Kortajarena-Urkola, Xabier, Pérez-Moreiras López, José Ignacio, Rengel-Jiménez, Ainhoa, Reviejo, Karlos, Sáez-Berbejillo, Alberto, Sánchez-Haza, Elou, Sebastián-Alda, Rosa, Solla-Ruiz, Itziar, Unamuno-Ugartemendia, Irati, Anza, Diego Vicente, Villanueva-Benito, Iñaki, Zabalo-Arrieta, Mar, Carrasco, Rafael, Climent, Vicente, Llamas, Patricio, Merino, Esperanza, Plazas, Joaquín, Reus, Sergio, Álvarez, Nemesio, Bravo-Ferrer, José María, Castelo, Laura, Cuenca, José, Llinares, Pedro, Miguez-Rey, Enrique, Rodríguez-Mayo, María, Sánchez, Efrén, Sousa-Regueiro, Dolores, Martínez, Francisco Javier, del Mar Alonso, null, Castro, Beatriz, Delgado-Melian, Teresa, Fernández-Sarabia, Javier, García-Rosado, Dácil, González-González, Julia, Lacalzada, Juan, Lorenzo de la Peña, Lissete, Pérez-Ramírez, Alina, Prada-Arrondo, Pablo, Rodríguez-Moreno, Fermín, Plata-Ciezar, Antonio, Asensi-Álvarez, Víctor, Costas, Carlos, de la Hera, Jesús, Fernández-Suárez, Jonnathan, Iglesias-Fraile, Lisardo, León-Arguero, Víctor, López-Menéndez, José, Mencia-Bajo, Pilar, Morales, Carlos, Moreno-Torrico, Alfonso, Palomo, Carmen, Paya-Martínez, Begoña, Rodríguez-Esteban, Ángeles, Rodríguez-García, Raquel, Telenti-Asensio, Mauricio, Almela, Manuel, Ambrosioni, Juan, Azqueta, Manuel, Brunet, Mercè, Bodro, Marta, Cartañá, Ramón, Falces, Carlos, Fita, Guillermina, Fuster, David, García de la Mària, Cristina, Hernández-Meneses, Marta, Llopis-Pérez, Jaume, Marco, Francesc, Miró, José M., Moreno, Asunción, Nicolás, David, Ninot, Salvador, Quintana, Eduardo, Paré, Carlos, Pereda, Daniel, Pericás, Juan M., Pomar, José L., Ramírez, José, Rovira, Irene, Sandoval, Elena, Sitges, Marta, Soy, Dolors, Téllez, Adrián, Tolosana, José M., Vidal, Bárbara, Vila, Jordi, Adán, Iván, Alonso, Juan Carlos, Álvarez-Uría, Ana, Bermejo, Javier, Bouza, Emilio, Cuerpo-Caballero, Gregorio, González-Mansilla, Ana, García-Leoni, Mª Eugenia, Gargallo, Esther, González-Ramallo, Víctor, Kestler-Hernández, Martha, Hualde, Amaia Mari, Machado, Marina, Marín, Mercedes, Martínez-Sellés, Manuel, Olmedo, María, Pedraz, Álvaro, Pinilla, Blanca, Pinto, Ángel, Rincón, Cristina, Rodríguez-Abella, Hugo, Rodríguez-Créixems, Marta, Segado, Antonio, Toledo, Neera, Valerio, Maricela, Vázquez, Pilar, Verde-Moreno, Eduardo, Antorrena, Isabel, Loeches, Belén, Moreno, Mar, Ramírez, Ulises, Rial-Bastón, Verónica, Romero, María, Rosillo, Sandra, Agüero-Balbín, Jesús, Amado, Cristina, Armiñanzas-Castillo, Carlos, Arnaiz, Ana, Arnaiz de las Revillas, Francisco, Cobo Belaustegui, Manuel, Fariñas, María Carmen, Fariñas-Álvarez, Concepción, Fernández-Sampedro, Marta, García, Iván, González-Rico, Claudia, Gutierrez-Fernandez, Laura, Gutiérrez-Cuadra, Manuel, Gutiérrez-Díez, José, Pajarón, Marcos, Parra, José Antonio, Teira, Ramón, Calderón-Parra, Jorge, Cobo, Marta, Domínguez, Fernando, García-Pavía, Pablo, Ramos-Martínez, Antonio, Sánchez-Romero, Isabel, Centella, Tomasa, Hermida, José Manuel, Moya, José Luis, Martín-Dávila, Pilar, Navas, Enrique, Oliva, Enrique, del Río, Alejandro, Rodríguez-Roda Stuart, Jorge, Ruiz, Soledad, Hidalgo-Tenorio, Carmen, Almendro-Delia, Manuel, Araji, Omar, Barquero, José Miguel, Calvo-Jambrina, Román, de Cueto, Marina, Gálvez-Acebal, Juan, Méndez, Irene, Morales, Isabel, López-Cortés, Luis Eduardo, Lepe, José Antonio, López-Haldón, José, Luque-Márquez, Rafael, Marín, Guillermo, Ortiz-Carrellán, Antonio, Sánchez-Domínguez, Eladio, Alonso, Luis Javier, Azcárate, Pedro, Azcona-Gutiérrez, José Manuel, Blanco, José Ramón, Cabrera-Villegas, Antonio, García-Álvarez, Lara, García-García, Concepción, Oteo, José Antonio, de Benito, Natividad, Gurguí, Mercé, Pacho, Cristina, Pericas, Roser, Pons, Guillem, Álvarez, null, Fernández, null, Martínez, Amparo, Prieto, null, Regueiro, Benito, Tijeira, null, Vega, Marino, Canut-Blasco, Andrés, Mollar, José Cordo, Gainzarain-Arana, Juan Carlos, García-Uriarte, Oscar, Martín-López, Alejandro, Ortiz de Zárate, Zuriñe, Urturi-Matos, José Antonio, Sánchez-Porto, Antonio, Úbeda-Iglesias, Alejandro, Arribas-Leal, José Mª, García-Vázquez, Elisa, Hernández-Torres, Alicia, Blázquez, Ana, de la Morena Valenzuela, Gonzalo, Alonso, Ángel, Aramburu, Javier, Calvo, Felicitas Elena, Moreno-Rodríguez, Anai, Tarabini-Castellani, Paola, Heredero-Gálvez, Eva, Maicas-Bellido, Carolina, Largo-Pau, José, Sepúlveda, Mª Antonia, Toledano-Sierra, Pilar, Iqbal-Mirza, Sadaf Zafar, Cascales-Alcolea, Eva, Keituqwa-Yañez, Ivan, Navarro-Martínez, Julián, Peláez-Ballesta, Ana, Moreno-Escobar, Eduardo, Peña-Monje, Alejandro, Sánchez-Cabrera, Valme, Vinuesa-García, David, Arrizabalaga-Asenjo, María, Cifuentes-Luna, Carmen, Núñez-Morcillo, Juana, Pérez-Seco, Mª Cruz, Villoslada-Gelabert, Aroa, Aured-Guallar, Carmen, Fernández-Abad, Nuria, García-Mangas, Pilar, Matamala-Adell, Marta, Palacián-Ruiz, Mª Pilar, Porres, Juan Carlos, Alcaraz-Vidal, Begoña, Cobos-Trigueros, Nazaret, Del Amor Espín, María Jesús, Giner-Caro, José Antonio, Jiménez-Sánchez, Roberto, Jimeno-Almazán, Amaya, Ortín-Freire, Alejandro, Viqueira-González, Monserrat, Pericás-Ramis, Pere, Ribas-Blanco, Mª Ángels, Ruiz de Gopegui Bordes, Enrique, Vidal-Bonet, Laura, Bellón-Munera, Mª Carmen, Escribano-Garaizabal, Elena, Tercero-Martínez, Antonia, Segura-Luque, Juan Carlos, Badía, Cristina, Boix-Palop, Lucía, Xercavins, Mariona, Ibars, Sónia, Bosch, Xerach, Gómez-Nebreda, Eloy, Horcajada-Herrera, Ibalia, Menduiña-Gallego, Irene, Pulido, Imanol, Marrero-Santiago, Héctor, de Miguel Martínez, Isabel, Pisos-Álamo, Elena, Aguilar-Blanco, Eva Mª, Catalán-González, Mercedes, Corres-Peiretti, María Angélica, Eixerés-Esteve, Andrea, Domínguez-Pérez, Laura, de Cossío Tejido, Santiago, Galván-Román, Francisco, García-Robles, José Antonio, López-Medrano, Francisco, López-Gude, Mª Jesús, Orellana-Miguel, Mª Ángeles, Pilkington, Patrick, Revilla-Ostalaza, Yolanda, Morales, Juan Ruiz, Ruiz-Solís, Sebastián, Collado, Ana Sabín, Sánchez-Fernández, Marcos, Rallo, Javier Solera, Martín, Jorge Solís, Cuervo, Guillermo, Escrihuela-Vidal, Francesc, Carratalà, Jordi, Grau, Inmaculada, Grillo, Sara, Ardanuy, Carmen, Berbel, Dámaris, Sánchez-Salado, José Carlos, Alegre, Oriol, Ruiz-Majoral, Alejandro, Sbraga, Fabrizio, Blasco, Arnau, Sánchez, Laura Gracia, Sánchez-Rodríguez, Iván, Álvarez, Beatriz, Cabello-Úbeda, Alfonso, Fernández-Roblas, Ricardo, Navas-Lobato, Miguel Ángel, Pello, Ana María, de la Peña Triguero, Mireia, Figueroa-Cerón, Ruth Esther, Ruiz-Gómez, Lara, Ble, Mireia, Horcajada-Gallego, Juan Pablo, Ginel, Antonio José, López, Inmaculada, Mas, Alexandra, Mestres, Antoni, Molina, Lluís, Serrat, Ramón, Ribas, Núria, Sánchez, Francisca, Silverio, Ana, Suárez, Marina, Sorlí, Luisa, Recasens, Lluís, Taurón, Manuel, 0000-0003-1189-1120, and Universidad de Cantabria

Subjects
Microbiology (medical), medicine.medical_specialty, medicine.medical_treatment, Charlson index, Infections, Hospital patients, Mural, Internal medicine, medicine, Endocarditis, Malalts hospitalitzats, business.industry, Brief Report, medicine.disease, Infeccions, Transplantation, Catheter, Non-valvular endocarditis, Infectious Diseases, Infective endocarditis, Etiology, Hemodialysis, Complication, business, human activities
Abstract

Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis infecciosa en España (GAMES)., [Introduction] Mural infective endocarditis (MIE) is a rare type of endovascular infection. We present a comprehensive series of patients with mural endocarditis., [Methods] Patients with infectious endocarditis (IE) from 35 Spanish hospitals were prospectively included in the GAMES registry between 2008 and 2017. MIEs were compared to non-MIEs. We also performed a literature search for cases of MIE published between 1979 and 2019 and compared them to the GAMEs series., [Results] Twenty-seven MIEs out of 3676 IEs were included. When compared to valvular IE (VIE) or device-associated IE (DIE), patients with MIE were younger (median age 59 years, p, [Conclusion] MIE is a rare entity. It is often a complication of catheter use, particularly in immunocompromised and hemodialysis patients. Fungal etiology is common. Mortality is similar to other IEs.

Published
2021

31. A Large Multicenter Prospective Study of Community-Onset Healthcare Associated Bacteremic Urinary Tract Infections in the Era of Multidrug Resistance: Even Worse than Hospital Acquired Infections?

Author

Gómez-Zorrilla, Silvia, Becerra-Aparicio, Federico, López Montesinos, Inmaculada, Ruiz de Gopegui, Enrique, Grau, Inmaculada, Pintado, Vicente, Padilla, Belén, Benito, Natividad, Boix-Palop, Lucía, Fariñas, Maria Carmen, Peñaranda, María, Gamallo, Maria Rocío, Martinez, Jose Antonio, Morte-Romea, Elena, Del Pozo, Jose Luis, Durán-Jordá, Xavier, Díaz-Regañón, Jazmin, López-Mendoza, Diego, Cantón, Rafael, Oliver, Antonio, Ruiz-Garbajosa, Patricia, Horcajada, Juan Pablo, Siverio, Ana, Gijón, Desiré, Merino, Irene, López-Causapé, Carla, Sabé, Nuria, Shaw, Evelyn, Berbel, Dámaris, Tubau Quintano, Fe, Sánchez Carrillo, Carlos, Cercenado, Emilia, Sendra, Elena, Rubio, Verónica, Rivera, Alba, Calvo, Esther, Badía, Cristina, Xercavins, Mariona, de Malet, Ana, Canoura-Fernández, Luis, Salvo, Soledad, Paño-Pardo, Jose Ramón, Carmona-Torre, Francisco, and Universidad de Cantabria

Subjects
Microbiology (medical), medicine.medical_specialty, Hospital-acquired infections, business.industry, medicine.drug_class, Proportional hazards model, Urinary system, Antibiotics, Logistic regression, medicine.disease, Urinary tract infections, Multiple drug resistance, Infectious Diseases, Multidrug resistant, Bacteremia, Internal medicine, Medicine, Bloodstream infections, business, Prospective cohort study, Community-onset healthcare-associated infections, Cohort study, Original Research
Abstract

Introduction: Healthcare-associated (HCA) infections represent a growing public health problem. The aim of this study was to compare community-onset healthcare associated (CO-HCA) bacteremic urinary tract infections (BUTI) and hospital-acquired (HA)-BUTI with special focus on multidrug resistances (MDR) and outcomes. Methods: ITUBRAS-project is a prospective multicenter cohort study of patients with HCA-BUTI. All consecutive hospitalized adult patients with CO-HCA-BUTI or HA-BUTI episode were included in the study. Exclusion criteria were: patients \ 18 years old, non-hospitalized patients, bacteremia from another source or primary bacteremia, non-healthcare related infections and infections caused by unusual pathogens of the urinary tract. Th main outcome variable was 30-day all-cause mortality with day 1 as the first day of positive blood culture. Logistic regression was used to analyze factors associated with clinical cure at hospital discharge and with receiving inappropriate initial antibiotic treatment. Cox regression was used to evaluate 30-day all-cause mortality. Results: Four hundred forty-three episodes were included, 223 CO-HCA-BUTI. Patients with CO-HCA-BUTI were older (p \ 0.001) and had more underlying diseases (p = 0.029) than those with HA-BUTI. The severity of the acute illness (Pitt score) was also higher in CO-HCABUTI (p = 0.026). Overall, a very high rate of MDR profiles (271/443, 61.2%) was observed, with no statistical differences between groups. In multivariable analysis, inadequate empirical treatment was associated with MDR profile (aOR 3.35; 95% CI 1.77?6.35), Pseudomonas aeruginosa (aOR 2.86; 95% CI 1.27?6.44) and Charlson index (aOR 1.11; 95% CI 1.01?1.23). Mortality was not associated with the site of acquisition of the infection or the presence of MDR profile. However, in the logistic regression analyses patients with CO-HCA-BUTI (aOR 0.61; 95% CI 0.40?0.93) were less likely to present clinical cure. Conclusion: The rate of MDR infections was worryingly high in our study. No differences in MDR rates were found between CO-HCA-BUTI and HA-BUTI, in the probability of receiving inappropriate empirical treatment or in 30-day mortality. However, CO-HCA-BUTIs were associated with worse clinical cure. Funding. This study and the journal’s Rapid Service Fee are sponsored and funded by MSD Spain. The study was also supported by Plan Nacional de I+D+i 2013–2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Economía, Industria y Competitividad, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/0004, RD16/ 0016/0005, RD16/0016/0007, RD16/0016/0010, RD16/0016/0011 and RD16/0016/0015), co-financed by the European Development Regional Fund ‘A way to achieve Europe’ (ERDF), Operative program Intelligent Growth 2014–2020.

Published
2021

33. Prevalence of Colorectal Neoplasms Among Patients With Enterococcus faecalis Endocarditis in the GAMES Cohort (2008–2017)

Author

Pericàs, Juan M., primary, Ambrosioni, Juan, additional, Muñoz, Patricia, additional, de Alarcón, Arístides, additional, Kestler, Martha, additional, Mari-Hualde, Amaia, additional, Moreno, Asunción, additional, Goenaga, Miguel Á., additional, Fariñas, M. Carmen, additional, Rodríguez-Álvarez, Regino, additional, Ojeda-Burgos, Guillermo, additional, Gálvez-Acebal, Juan, additional, Hidalgo-Tenorio, Carmen, additional, Noureddine, Mariam, additional, Miró, José M., additional, Sánchez, Fernando Fernández, additional, Rosas, Gabriel, additional, Lima, Javier de la Torre, additional, Blanco, Roberto, additional, Boado, María Victoria, additional, Lázaro, Marta Campaña, additional, Crespo, Alejandro, additional, Goikoetxea, Josune, additional, Iruretagoyena, José Ramón, additional, Zuazabal, Josu Irurzun, additional, López-Soria, Leire, additional, Montejo, Miguel, additional, Nieto, Javier, additional, Rodrigo, David, additional, Rodríguez, Regino, additional, Vitoria, Yolanda, additional, Voces, Roberto, additional, López, Ma Victoria García, additional, Georgieva, Radka Ivanova, additional, Ojeda, Guillermo, additional, Bailón, Isabel Rodríguez, additional, Morales, Josefa Ruiz, additional, Cuende, Ana María, additional, Echeverría, Tomás, additional, Fuerte, Ana, additional, Gaminde, Eduardo, additional, Goenaga, Miguel Ángel, additional, Idígoras, Pedro, additional, Iribarren, José Antonio, additional, Yarza, Alberto Izaguirre, additional, Urkola, Xabier Kortajarena, additional, Reviejo, Carlos, additional, Carrasco, Rafael, additional, Climent, Vicente, additional, Llamas, Patricio, additional, Merino, Esperanza, additional, Plazas, Joaquín, additional, Reus, Sergio, additional, Álvarez, Nemesio, additional, Bravo-Ferrer, José María, additional, Castelo, Laura, additional, Cuenca, José, additional, Llinares, Pedro, additional, Rey, Enrique Miguez, additional, Mayo, María Rodríguez, additional, Sánchez, Efrén, additional, Regueiro, Dolores Sousa, additional, Martínez, Francisco Javier, additional, del Mar Alonso, Ma, additional, Castro, Beatriz, additional, Rosado, Dácil García, additional, del Carmen Durán, Ma, additional, Gómez, Ma Antonia Miguel, additional, Lacalzada, Juan, additional, Nassar, Ibrahim, additional, Ciezar, Antonio Plata, additional, Iglesias, José Ma Reguera, additional, Álvarez, Víctor Asensi, additional, Costas, Carlos, additional, Hera, Jesús de la, additional, Suárez, Jonnathan Fernández, additional, Fraile, Lisardo Iglesias, additional, Arguero, Víctor León, additional, Menéndez, José López, additional, Bajo, Pilar Mencia, additional, Morales, Carlos, additional, Torrico, Alfonso Moreno, additional, Palomo, Carmen, additional, Martínez, Begoña Paya, additional, Esteban, Ángeles Rodríguez, additional, García, Raquel Rodríguez, additional, Asensio, Mauricio Telenti, additional, Almela, Manuel, additional, Azqueta, Manuel, additional, Brunet, Mercè, additional, Bodro, Marta, additional, Cartañá, Ramón, additional, Falces, Carlos, additional, Fita, Guillermina, additional, Fuster, David, additional, García de la Mària, Cristina, additional, García-Pares, Delia, additional, Hernández-Meneses, Marta, additional, Pérez, Jaume Llopis, additional, Marco, Francesc, additional, Nicolás, David, additional, Ninot, Salvador, additional, Quintana, Eduardo, additional, Paré, Carlos, additional, Pereda, Daniel, additional, Pericás, Juan M., additional, Pomar, José L., additional, Ramírez, José, additional, Rovira, Irene, additional, Sandoval, Elena, additional, Sitges, Marta, additional, Soy, Dolors, additional, Téllez, Adrián, additional, Tolosana, José M., additional, Vidal, Bárbara, additional, Vila, Jordi, additional, Adán, Iván, additional, Bermejo, Javier, additional, Bouza, Emilio, additional, Celemín, Daniel, additional, Caballero, Gregorio Cuerpo, additional, Montero, Antonia Delgado, additional, Mansilla, Ana García, additional, Leoni, Ma Eugenia García, additional, Ramallo, Víctor González, additional, Hernández, Martha Kestler, additional, Hualde, Amaia Mari, additional, Marín, Mercedes, additional, Martínez-Sellés, Manuel, additional, Rincón, Cristina, additional, Rodríguez-Abella, Hugo, additional, Rodríguez-Créixems, Marta, additional, Pinilla, Blanca, additional, Pinto, Ángel, additional, Valerio, Maricela, additional, Vázquez, Pilar, additional, Moreno, Eduardo Verde, additional, Antorrena, Isabel, additional, Loeches, Belén, additional, Quirós, Alejandro Martín, additional, Moreno, Mar, additional, Ramírez, Ulises, additional, Bastón, Verónica Rial, additional, Romero, María, additional, Saldaña, Araceli, additional, Balbín, Jesús Agüero, additional, Castillo, Carlos Armiñanzas, additional, Arnaiz, Ana, additional, de las Revillas, Francisco Arnaiz, additional, Belaustegui, Manuel Cobo, additional, Fariñas, María Carmen, additional, Fariñas-Álvarez, Concepción, additional, Izquierdo, Rubén Gómez, additional, García, Iván, additional, Rico, Claudia González, additional, Gutiérrez-Cuadra, Manuel, additional, Díez, José Gutiérrez, additional, Pajarón, Marcos, additional, Parra, José Antonio, additional, Teira, Ramón, additional, Zarauza, Jesús, additional, Calderón Parra, Jorge, additional, Cobo, Marta, additional, Domínguez, Fernando, additional, Fortaleza, Alberto, additional, Pavía, Pablo García, additional, González, Jesús, additional, Cruz, Ana Fernández, additional, Múñez, Elena, additional, Ramos, Antonio, additional, Romero, Isabel Sánchez, additional, Centella, Tomasa, additional, Hermida, José Manuel, additional, Moya, José Luis, additional, Martín-Dávila, Pilar, additional, Navas, Enrique, additional, Oliva, Enrique, additional, Río, Alejandro del, additional, Rodríguez-Roda Stuart, Jorge, additional, Ruiz, Soledad, additional, Tenorio, Carmen Hidalgo, additional, Delia, Manuel Almendro, additional, Araji, Omar, additional, Barquero, José Miguel, additional, Jambrina, Román Calvo, additional, de Cueto, Marina, additional, Acebal, Juan Gálvez, additional, Méndez, Irene, additional, Morales, Isabel, additional, López-Cortés, Luis Eduardo, additional, García, Emilio, additional, Haro, Juan Luis, additional, Lepe, José Antonio, additional, López, Francisco, additional, Luque, Rafael, additional, Alonso, Luis Javier, additional, Azcárate, Pedro, additional, Azcona Gutiérrez, José Manuel, additional, Blanco, José Ramón, additional, Villegas, Antonio Cabrera, additional, García-Álvarez, Lara, additional, Oteo, José Antonio, additional, Sanz, Mercedes, additional, de Benito, Natividad, additional, Gurguí, Mercé, additional, Pacho, Cristina, additional, Pericas, Roser, additional, Pons, Guillem, additional, Álvarez, M., additional, Fernández, A.L., additional, Martínez, Amparo, additional, Prieto, A., additional, Regueiro, Benito, additional, Tijeira, E., additional, Vega, Marino, additional, Blasco, Andrés Canut, additional, Mollar, José Cordo, additional, Gainzarain Arana, Juan Carlos, additional, Uriarte, Oscar García, additional, López, Alejandro Martín, additional, Ortiz de Zárate, Zuriñe, additional, Urturi Matos, José Antonio, additional, Gloria, García-Domínguez, additional, Antonio, Sánchez-Porto, additional, Leal, José Ma Arribas, additional, Vázquez, Elisa García, additional, Torres, Alicia Hernández, additional, Blázquez, Ana, additional, Valenzuela, Gonzalo de la Morena, additional, Alonso, Ángel, additional, Aramburu, Javier, additional, Calvo, Felicitas Elena, additional, Rodríguez, Anai Moreno, additional, Tarabini-Castellani, Paola, additional, Gálvez, Eva Heredero, additional, Bellido, Carolina Maicas, additional, Pau, José Largo, additional, Sepúlveda, Ma Antonia, additional, Sierra, Pilar Toledano, additional, Iqbal-Mirza, Sadaf Zafar, additional, Alcolea, Eva Cascales, additional, Yañez, Ivan Keituqwa, additional, Martínez, Julián Navarro, additional, Ballesta, Ana Peláez, additional, Escobar, Eduardo Moreno, additional, Monje, Alejandro Peña, additional, Cabrera, Valme Sánchez, additional, García, David Vinuesa, additional, Asenjo, María Arrizabalaga, additional, Luna, Carmen Cifuentes, additional, Morcillo, Juana Núñez, additional, Seco, Ma Cruz Pérez, additional, Gelabert, Aroa Villoslada, additional, Guallar, Carmen Aured, additional, Abad, Nuria Fernández, additional, Mangas, Pilar García, additional, Adell, Marta Matamala, additional, Ruiz, Ma Pilar Palacián, additional, Porres, Juan Carlos, additional, Vidal, Begoña Alcaraz, additional, Trigueros, Nazaret Cobos, additional, Del Amor Espín, María Jesús, additional, Giner Caro, José Antonio, additional, Sánchez, Roberto Jiménez, additional, Almazán, Amaya Jimeno, additional, Freire, Alejandro Ortín, additional, González, Monserrat Viqueira, additional, Ramis, Pere Pericás, additional, Blanco, Ma Ángels Ribas, additional, Ruiz de Gopegui Bordes, Enrique, additional, Bonet, Laura Vidal, additional, Munera, Ma Carmen Bellón, additional, Garaizabal, Elena Escribano, additional, Martínez, Antonia Tercero, additional, Segura Luque, Juan Carlos, additional, Badía, Cristina, additional, Palop, Lucía Boix, additional, Xercavins, Mariona, additional, Eloy Gómez Nebreda, Sónia Ibars., additional, Herrera, Ibalia Horcajada, additional, Gallego Héctor Marrero Santiago, Irene Menduiña, additional, de Miguel Martínez, Isabel, additional, and Álamo, Elena Pisos, additional

Published
2021
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34. Hospital-acquired Pneumococcal bacteremia. (Major Article)

Author

Canet, Joan-Josep, Juan, Natalia, Xercavins, Mariona, Freixas, Nuria, and Garau, Javier

Subjects
Cross infection, Nosocomial infections, Pneumococcal infections -- Causes of, Bacteremia, Health, Health care industry
Published
2002

35. Failure of macrolide antibiotic treatment in patients with bacteremia due to erythromycin-resistant Streptococcus pneumoniae. (Major Article)

Author

Lonks, John R., Garau, Javier, Gomez, Lucia, Xercavins, Mariona, de Echaguen, Anna Ochoa, Gareen, Ilana F., Reiss, Philip T., and Medeiros, Antone A.

Subjects
Macrolide antibiotics -- Physiological aspects, Drug resistance in microorganisms -- Care and treatment, Bacteremia -- Care and treatment, Streptococcal infections -- Complications, Health, Health care industry
Published
2002

36. Applicability of Outpatient Quality Indicators for Appropriate Antibiotic Use in a Primary Health Care Area: a Point Prevalence Survey

Author

March-López, Pablo, primary, Madridejos, Rosa, additional, Tomas, Rosa, additional, Boix-Palop, Lucía, additional, Arcenillas, Paula, additional, Gómez, Lucía, additional, Padilla, Emma, additional, Xercavins, Mariona, additional, Martinez, Laura, additional, Massats, Úrsula, additional, Badia, Cristina, additional, Lledó, Joan Manuel Sánchez, additional, Casino, Alberto Domingo, additional, Nicolás, Jordi, additional, and Calbo, Esther, additional

Published
2020
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38. Impact of a Multifaceted Antimicrobial Stewardship Intervention in a Primary Health Care Area: A Quasi-Experimental Study

Author

March-López, Pablo, primary, Madridejos, Rosa, additional, Tomas, Rosa, additional, Boix, Lucía, additional, Arcenillas, Paula, additional, Gómez, Lucía, additional, Padilla, Emma, additional, Xercavins, Mariona, additional, Martinez, Laura, additional, Riera, Montserrat, additional, Badia, Cristina, additional, Nicolás, Jordi, additional, and Calbo, Esther, additional

Published
2020
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39. A Contemporary Picture of Enterococcal Endocarditis

Author

Pericàs, Juan M., primary, Llopis, Jaume, additional, Muñoz, Patricia, additional, Gálvez-Acebal, Juan, additional, Kestler, Martha, additional, Valerio, Maricela, additional, Hernández-Meneses, Marta, additional, Goenaga, Miguel Á., additional, Cobo-Belaustegui, Manuel, additional, Montejo, Miguel, additional, Ojeda-Burgos, Guillermo, additional, Sousa-Regueiro, M. Dolores, additional, de Alarcón, Arístides, additional, Ramos-Martínez, Antonio, additional, Miró, José M., additional, Sánchez, Fernando Fernández, additional, Noureddine, Mariam, additional, Rosas, Gabriel, additional, de la Torre Lima, Javier, additional, Blanco, Roberto, additional, Boado, María Victoria, additional, Campaña Lázaro, Marta, additional, Crespo, Alejandro, additional, Goikoetxea, Josune, additional, Iruretagoyena, José Ramón, additional, Irurzun Zuazabal, Josu, additional, López-Soria, Leire, additional, Nieto, Javier, additional, Rodrigo, David, additional, Rodríguez, Regino, additional, Vitoria, Yolanda, additional, Voces, Roberto, additional, García López, Ma Victoria, additional, Georgieva, Radka Ivanova, additional, Ojeda, Guillermo, additional, Rodríguez Bailón, Isabel, additional, Ruiz Morales, Josefa, additional, María Cuende, Ana, additional, Echeverría, Tomás, additional, Fuerte, Ana, additional, Gaminde, Eduardo, additional, Goenaga, Miguel Ángel, additional, Idígoras, Pedro, additional, Antonio Iribarren, José, additional, Izaguirre Yarza, Alberto, additional, Kortajarena Urkola, Xabier, additional, Reviejo, Carlos, additional, Carrasco, Rafael, additional, Climent, Vicente, additional, Llamas, Patricio, additional, Merino, Esperanza, additional, Plazas, Joaquín, additional, Reus, Sergio, additional, Álvarez, Nemesio, additional, Bravo-Ferrer, José María, additional, Castelo, Laura, additional, Cuenca, José, additional, Llinares, Pedro, additional, Miguez Rey, Enrique, additional, Rodríguez Mayo, María, additional, Sánchez, Efrén, additional, Sousa Regueiro, Dolores, additional, Javier Martínez, Francisco, additional, Alonso, Ma del Mar, additional, Castro, Beatriz, additional, García Rosado, Dácil, additional, Durán, Ma del Carmen, additional, Miguel Gómez, Ma Antonia, additional, Lacalzada, Juan, additional, Nassar, Ibrahim, additional, Plata Ciezar, Antonio, additional, Reguera Iglesias, José Ma, additional, Asensi Álvarez, Víctor, additional, Costas, Carlos, additional, de la Hera, Jesús, additional, Fernández Suárez, Jonnathan, additional, Iglesias Fraile, Lisardo, additional, León Arguero, Víctor, additional, López Menéndez, José, additional, Mencia Bajo, Pilar, additional, Morales, Carlos, additional, Moreno Torrico, Alfonso, additional, Palomo, Carmen, additional, Paya Martínez, Begoña, additional, Rodríguez Esteban, Ángeles, additional, Rodríguez García, Raquel, additional, Telenti Asensio, Mauricio, additional, Almela, Manuel, additional, Ambrosioni, Juan, additional, Azqueta, Manuel, additional, Brunet, Mercè, additional, Bodro, Marta, additional, Cartañá, Ramón, additional, Falces, Carlos, additional, Fita, Guillermina, additional, Fuster, David, additional, García de la Mària, Cristina, additional, García-Pares, Delia, additional, Llopis Pérez, Jaume, additional, Marco, Francesc, additional, Moreno, Asunción, additional, Nicolás, David, additional, Ninot, Salvador, additional, Quintana, Eduardo, additional, Paré, Carlos, additional, Pereda, Daniel, additional, Pericás, Juan M., additional, Pomar, José L., additional, Ramírez, José, additional, Rovira, Irene, additional, Sandoval, Elena, additional, Sitges, Marta, additional, Soy, Dolors, additional, Téllez, Adrián, additional, Tolosana, José M., additional, Vidal, Bárbara, additional, Vila, Jordi, additional, Adán, Iván, additional, Bermejo, Javier, additional, Bouza, Emilio, additional, Celemín, Daniel, additional, Cuerpo Caballero, Gregorio, additional, Delgado Montero, Antonia, additional, García Mansilla, Ana, additional, García Leoni, Ma Eugenia, additional, González Ramallo, Víctor, additional, Kestler Hernández, Martha, additional, Hualde, Amaia Mari, additional, Marín, Mercedes, additional, Martínez-Sellés, Manuel, additional, Rincón, Cristina, additional, Rodríguez-Abella, Hugo, additional, Rodríguez-Créixems, Marta, additional, Pinilla, Blanca, additional, Pinto, Ángel, additional, Vázquez, Pilar, additional, Verde Moreno, Eduardo, additional, Antorrena, Isabel, additional, Loeches, Belén, additional, Martín Quirós, Alejandro, additional, Moreno, Mar, additional, Ramírez, Ulises, additional, Rial Bastón, Verónica, additional, Romero, María, additional, Saldaña, Araceli, additional, Agüero Balbín, Jesús, additional, Armiñanzas Castillo, Carlos, additional, Arnaiz, Ana, additional, Arnaiz de las Revillas, Francisco, additional, Cobo Belaustegui, Manuel, additional, Fariñas, María Carmen, additional, Fariñas-Álvarez, Concepción, additional, Gómez Izquierdo, Rubén, additional, García, Iván, additional, González Rico, Claudia, additional, Gutiérrez-Cuadra, Manuel, additional, Gutiérrez Díez, José, additional, Pajarón, Marcos, additional, Parra, José Antonio, additional, Teira, Ramón, additional, Zarauza, Jesús, additional, Calderón Parra, Jorge, additional, Cobo, Marta, additional, Domínguez, Fernando, additional, Fortaleza, Alberto, additional, García Pavía, Pablo, additional, González, Jesús, additional, Fernández Cruz, Ana, additional, Múñez, Elena, additional, Ramos, Antonio, additional, Sánchez Romero, Isabel, additional, Centella, Tomasa, additional, Hermida, José Manuel, additional, Moya, José Luis, additional, Martín-Dávila, Pilar, additional, Navas, Enrique, additional, Oliva, Enrique, additional, del Río, Alejandro, additional, Rodríguez-Roda Stuart, Jorge, additional, Ruiz, Soledad, additional, Hidalgo Tenorio, Carmen, additional, Almendro Delia, Manuel, additional, Araji, Omar, additional, Barquero, José Miguel, additional, Calvo Jambrina, Román, additional, de Cueto, Marina, additional, Gálvez Acebal, Juan, additional, Méndez, Irene, additional, Morales, Isabel, additional, López-Cortés, Luis Eduardo, additional, García, Emilio, additional, Haro, Juan Luis, additional, Lepe, José Antonio, additional, López, Francisco, additional, Luque, Rafael, additional, Alonso, Luis Javier, additional, Azcárate, Pedro, additional, Azcona Gutiérrez, José Manuel, additional, Blanco, José Ramón, additional, Cabrera Villegas, Antonio, additional, García-Álvarez, Lara, additional, Oteo, José Antonio, additional, Sanz, Mercedes, additional, de Benito, Natividad, additional, Gurguí, Mercé, additional, Pacho, Cristina, additional, Pericas, Roser, additional, Pons, Guillem, additional, Álvarez, M., additional, Fernández, A.L., additional, Martínez, Amparo, additional, Prieto, A., additional, Regueiro, Benito, additional, Tijeira, E., additional, Vega, Marino, additional, Canut Blasco, Andrés, additional, Cordo Mollar, José, additional, Gainzarain Arana, Juan Carlos, additional, García Uriarte, Oscar, additional, Martín López, Alejandro, additional, Ortiz de Zárate, Zuriñe, additional, Urturi Matos, José Antonio, additional, Gloria, García-Domínguez, additional, Antonio, Sánchez-Porto, additional, Arribas Leal, José Ma, additional, García Vázquez, Elisa, additional, Hernández Torres, Alicia, additional, Blázquez, Ana, additional, de la Morena Valenzuela, Gonzalo, additional, Alonso, Ángel, additional, Aramburu, Javier, additional, Calvo, Felicitas Elena, additional, Moreno Rodríguez, Anai, additional, Tarabini-Castellani, Paola, additional, Heredero Gálvez, Eva, additional, Maicas Bellido, Carolina, additional, Largo Pau, José, additional, Sepúlveda, Ma Antonia, additional, Toledano Sierra, Pilar, additional, Iqbal-Mirza, Sadaf Zafar, additional, Cascales Alcolea, Eva, additional, Keituqwa Yañez, Ivan, additional, Martínez, Julián Navarro, additional, Ballesta, Ana Peláez, additional, Moreno Escobar, Eduardo, additional, Peña Monje, Alejandro, additional, Sánchez Cabrera, Valme, additional, Vinuesa García, David, additional, Arrizabalaga Asenjo, María, additional, Cifuentes Luna, Carmen, additional, Núñez Morcillo, Juana, additional, Pérez Seco, Ma Cruz, additional, Villoslada Gelabert, Aroa, additional, Aured Guallar, Carmen, additional, Fernández Abad, Nuria, additional, García Mangas, Pilar, additional, Matamala Adell, Marta, additional, Palacián Ruiz, Ma Pilar, additional, Porres, Juan Carlos, additional, Alcaraz Vidal, Begoña, additional, Cobos Trigueros, Nazaret, additional, Del Amor Espín, María Jesús, additional, Giner Caro, José Antonio, additional, Jiménez Sánchez, Roberto, additional, Jimeno Almazán, Amaya, additional, Ortín Freire, Alejandro, additional, Viqueira González, Monserrat, additional, Pericás Ramis, Pere, additional, Ribas Blanco, Ma Ángels, additional, Ruiz de Gopegui Bordes, Enrique, additional, Vidal Bonet, Laura, additional, Bellón Munera, Ma Carmen, additional, Escribano Garaizabal, Elena, additional, Tercero Martínez, Antonia, additional, Segura Luque, Juan Carlos, additional, Badía, Cristina, additional, Boix Palop, Lucía, additional, Xercavins, Mariona, additional, Ibars, Sónia, additional, Nebreda, Eloy Gómez, additional, Horcajada Herrera, Ibalia, additional, Menduiña Gallego, Irene, additional, Marrero Santiago, Héctor, additional, de Miguel Martínez, Isabel, additional, Pisos Álamo, Elena, additional, Díaz Pedroche, Carmen, additional, Chaves, Fernando, additional, de Cossío, Santiago, additional, López Medrano, Francisco, additional, López, Ma Jesús, additional, Solera, Javier, additional, Solís, Jorge, additional, Ardanuy, Carmen, additional, Cuervo Requena, Guillermo, additional, Grillo, Sara, additional, and Ruiz Majoral, Alejandro, additional

Published
2020
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40. IL7RA rs6897932 Polymorphism Is Associated with Better CD4+ T-Cell Recovery in HIV Infected Patients Starting Combination Antiretroviral Therapy

Author

Resino, Salvador, Navarrete-Munoz, Maria A., Blanco, Julia, Pacheco, Yolanda M., Castro, Ivan, Berenguer, Juan, Santos, Jesus, Vera-Mendez, Francisco J., Gorgolas, Miguel, Angeles Jimenez-Sousa, M. A., Benito, Jose M., Rallon, Norma, Moreno, Santiago, Jarrin, Inma, Dalmau, David, Luisa Navarro, Maria, Isabel Gonzalez, Maria, Luis Blanco, Jose, Garcia, Federico, Rubio, Rafael, Antonio Iribarren, Jose, Gutierrez, Felix, Vidal, Francesc, Gonzalez, Juan, Alejos, Belen, Hernando, Victoria, Moreno, Cristina, Iniesta, Carlos, Garcia Sousa, Luis Miguel, Sanz Perez, Nieves, Angeles Munoz-Fernandez, M., Maria Garcia-Merino, Isabel, Consuegra Fernandez, Irene, Gomez Rico, Coral, Gallego de la Fuente, Jorge, Palau Concejo, Paula, Portilla, Joaquin, Merino, Esperanza, Reus, Sergio, Boix, Vicente, Giner, Livia, Gadea, Carmen, Portilla, Irene, Pampliega, Maria, Diez, Marcos, Carlos Rodriguez, Juan, Sanchez-Paya, Jose, Luis Gomez, Juan, Hernandez, Jehovana, Remedios Aleman, Maria, del Mar Alonso, Maria, Inmaculada Hernandez, Maria, Diaz-Flores, Felicitas, Garcia, Dacil, Pelazas, Ricardo, Lopez Lirola, Ana, Sanz Moreno, Jose, Arranz Caso, Alberto, Hernandez Gutierrez, Cristina, Novella Mena, Maria, Pulido, Federico, Bisbal, Otilia, Hernando, Asuncion, Dominguez, Lourdes, Crestelo, David Rial, Bermejo, Laura, Santacreu, Mireia, Arrizabalaga, Julio, Jose Aramburu, Maria, Camino, Xabier, Rodriguez-Arrondo, Francisco, Angel von Wichmann, Miguel, Pascual Tome, Lidia, Angel Goenaga, Miguel, Bustinduy, Ma Jesus, Azkune, Harkaitz, Ibarguren, Maialen, Lizardi, Aitziber, Kortajarena, Xabier, Masia, Mar, Padilla, Sergio, Navarro, Andres, Montolio, Fernando, Robledano, Catalina, Gregori Colome, Joan, Adsuar, Araceli, Pascual, Rafael, Fernandez, Marta, Garcia, Elena, Alberto Garcia, Jose, Barber, Xavier, Lopez Bernaldo de Quiros, Juan Carlos, Gutierrez, Isabel, Ramirez, Margarita, Padilla, Belen, Gijon, Paloma, Aldamiz-Echevarria, Teresa, Tejerina, Francisco, Jose Parras, Francisco, Balsalobre, Pascual, Diez, Cristina, Perez Latorre, Leire, Peraire, Joaquin, Vilades, Consuelo, Veloso, Sergio, Vargas, Montserrat, Lopez-Dupla, Miguel, Olona, Montserrat, Rull, Anna, Rodriguez-Gallego, Esther, Alba, Veronica, Montero Alonso, Marta, Lopez Aldeguer, Jose, Blanes Julia, Marino, Tasias Pitarch, Maria, Castro Hernandez, Ivan, Calabuig Munoz, Eva, Cuellar Tovar, Sandra, Salavert Lleti, Miguel, Fernandez Navarro, Juan, Gonzalez-garcia, Juan, Arnalich, Francisco, Ramon Arribas, Jose, Bernardino de la Serna, Jose Ignacio, Miguel Castro, Juan, Escosa, Luis, Herranz, Pedro, Hontanon, Victor, Garcia-Bujalance, Silvia, Garcia Lopez-Hortelano, Milagros, Gonzalez-Baeza, Alicia, Luz Martin-Carbonero, Maria, Mayoral, Mario, Jose Mellado, Maria, Esteban Mican, Rafael, Montejano, Rocio, Luisa Montes, Maria, Moreno, Victoria, Perez-Valero, Ignacio, Rodes, Berta, Sainz, Talia, Sendagorta, Elena, Stella Alcariz, Natalia, Valencia, Eulalia, Ramon Blanco, Jose, Antonio Oteo, Jose, Ibarra, Valvanera, Metola, Luis, Sanz, Mercedes, Perez-Martinez, Laura, Jaen, Angels, Sanmarti, Montse, Cairo, Mireia, Martinez-Lacasa, Javier, Velli, Pablo, Font, Roser, Xercavins, Mariona, Alonso, Noemi, Rivero, Maria, Reparaz, Jesus, Ruiz de Alda, Maria Gracia, de Leon Cano, Maria Teresa, Ruiz de Galarreta, Beatriz Pierola, Segura, Ferran, Jose Amengual, Maria, Navarro, Gemma, Sala, Montserrat, Cervantes, Manuel, Pineda, Valentin, Calzado, Sonia, Navarro, Marta, de los Santos, Ignacio, Sanz Sanz, Jesus, Salas Aparicio, Ana, Sarria Cepeda, Cristina, Garcia-Fraile Fraile, Lucio, Martin Gayo, Enrique, Luis Casado, Jose, Dronda, Fernando, Moreno, Ana, Perez Elias, Maria Jesus, Gomez Ayerbe, Cristina, Gutierrez, Carolina, Madrid, Nadia, del Campo Terron, Santos, Marti, Paloma, Ansa, Uxua, Serrano, Sergio, Jesus Vivancos, Maria, Bernal, Enrique, Cano, Alfredo, Alcaraz Garcia, Antonia, Bravo Urbieta, Joaquin, Munoz, Angeles, Jose Alcaraz, Maria, del Carmen Villalba, Maria, Hernandez, Jose, Pena, Alejandro, Munoz, Leopoldo, Casas, Paz, Alvarez, Marta, Chueca, Natalia, Vinuesa, David, Martinez-Montes, Clara, Del Romero, Jorge, Rodriguez, Carmen, Puerta, Teresa, Carlos Carrio, Juan, Vera, Mar, Ballesteros, Juan, Ayerdi, Oskar, Riera, Melchor, Penaranda, Maria, Leyes, Maria, Ribas, Ma Angels, Campins, Antoni A., Vidal, Carmen, Fanjul, Francisco, Murillas, Javier, Homar, Francisco, Gomez Ayerbe, Crisitina, Viciana, Isabel, Palacios, Rosario, Maria Gonzalez, Carmen, Viciana, Pompeyo, Espinosa, Nuria, Fernando Lopez-Cortes, Luis, Podzamczer, Daniel, Ferrer, Elena, Imaz, Arkaitz, Tiraboschi, Juan, Silva, Ana, Saumoy, Maria, Olalla, Julian, del Arco, Alfonso, de la Torre, Javier, Luis Prada, Jose, de Lomas Guerrero, Jose Maria Garcia, Perez Stachowski, Javier, Juan Martinez, Onofre, Jesus Vera, Francisco, Martinez, Lorena, Garcia, Josefina, Alcaraz, Begona, Jimeno, Amaya, Castro Iglesias, Angeles, Pernas Souto, Berta, Mena de Cea, Alvaro, Galera, Carlos, Albendin, Helena, Perez, Aurora, Iborra, Asuncion, Moreno, Antonio, Merlos, Maria Angustias, Vidal, Asuncion, Suarez-Garcia, Ines, Malmierca, Eduardo, Gonzalez-Ruano, Patricia, Martin Rodrigo, Dolores, Ruiz Seco, Ma Pilar, Omar Mohamed-Balghata, Mohamed, Gomez Vidal, Maria Amparo, Estrada Perez, Vicente, Tellez Molina, Maria Jesus, Vergas Garcia, Jorge, Perez-Somarriba Moreno, Juncal, Cabello, Alfonso, Alvarez, Beatriz, Prieto, Laura, Galindo Puerto, Maria Jose, Fernando Vilalta, Ramon, Ferrer Ribera, Ana, Rivero Roman, Antonio, Brieva Herrero, Maria Teresa, Rivero Juarez, Antonio, Lopez Lopez, Pedro, Machuca Sanchez, Isabel, Pena Martinez, Jose, Cervero Jimenez, Miguel, Torres Perea, Rafael, Jusdado Ruiz-Capillas, Juan Jose, Pineda, Juan A., CoRIS HIV Biobank Integrated Spani, Instituto de Salud Carlos III, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), European Commission, Resino, Salvador, Castro, Iván, Resino, Salvador [0000-0001-8783-0450], and Castro, Iván [0000-0001-9938-2122]

Subjects
Male, 0301 basic medicine, humanos, lcsh:QR1-502, HIV Infections, Biochemistry, Gastroenterology, lcsh:Microbiology, 0302 clinical medicine, Receptor subunit, Genotype, Hiv infected patients, Drug Interactions, 030212 general & internal medicine, mediana edad, Cd4 t cell, Brief Report, immune reconstitution, Middle Aged, adulto, IL7RA, antirretrovirales, interacciones farmacológicas, Anti-Retroviral Agents, Female, SNPs, Adult, Cart, medicine.medical_specialty, Single-nucleotide polymorphism, cART, Polymorphism, Single Nucleotide, 03 medical and health sciences, Internal medicine, Statistical significance, medicine, Humans, Molecular Biology, Receptors, Interleukin-7, business.industry, HIV, Antiretroviral therapy, CD4, CD4 Lymphocyte Count, recuento de linfocitos CD4, 030104 developmental biology, infecciones por VIH, genotipo, business
Abstract

This article belongs to the Section Molecular Medicine., Interleukin-7 receptor subunit alpha (IL7RA) rs6897932 polymorphism IS related to CD4+ recovery after combination antiretroviral therapy (cART), but no studies so far have analyzed its potential impact in patients with very low CD4+ T-cells count. We aimed to analyze the association between IL7RA rs6897932 polymorphism and CD4+ T-cells count restoration in HIV-infected patients starting combination antiretroviral therapy (cART) with CD4+ T-cells count 20% and was in Hardy–Weinberg equilibrium (p = 0.550). Of 411 patients, 256 carried the CC genotype, while 155 had the CT/TT genotype. The CT/TT genotype was associated with a higher slope of CD4+ T-cells recovery (arithmetic mean ratio; AMR = 1.16; p = 0.016), higher CD4+ T-cells increase (AMR = 1.19; p = 0.004), and higher CD4+ T-cells count at the end of follow-up (AMR = 1.13; p = 0.006). Besides, rs6897932 CT/TT was related to a higher odds of having a value of CD4+ T-cells at the end of follow-up ≥500 CD4+ cells/mm3 (OR = 2.44; p = 0.006). After multiple testing correction (Benjamini–Hochberg), only the increase of ≥ 400 CD4+ cells/mm3 lost statistical significance (p = 0.052). IL7RA rs6897932 CT/TT genotype was related to a better CD4+ T-cells recovery and it could be used to improve the management of HIV-infected patients starting cART with CD4+ T-cells count, This study has been (partially) funded by grants RD12/0017/0031 and D16/0025/0013 to JMB, and RD12/0017/0024 and RD16CIII/0002/0002 to SR as part of the Health Research and Development Strategy, State Plan for Scientific and Technical Research and Innovation (2008–2011; 2013–2016) and co-financed by Institute of Health Carlos III, ISCIII—Sub-Directorate General for Research Assessment and Promotion and European Regional Development Fund (ERDF). MA Jiménez-Sousa is funded by project RD16CIII/0002/0002; MA Navarrete-Muñoz is co-funded by RD16/0025/0013 project and Intramural Research Scholarship from IIS-FJD. N Rallón is a Miguel Servet investigator from the ISCIII [grant number CP14/00198].

Published
2019

41. VDR rs2228570 Polymorphism Is Related to Non-Progression to AIDS in Antiretroviral Therapy Naïve HIV-Infected Patients

Author

Jimenez-Sousa, Maria A., Luis Jimenez, Jose, Fernandez-Rodriguez, Amanda, Brochado-Kith, Oscar, Maria Bellon, Jose, Gutierrez, Felix, Diez, Cristina, Bernal-Morell, Enrique, Viciana, Pompeyo, Munoz-Fernandez, Maria A., Resino, Salvador, Moreno, Santiago, del Amo, Julia, Dalmau, David, Luisa Navarro, Maria, Isabel Gonzalez, Maria, Luis Blanco, Jose, Garcia, Federico, Rubio, Rafael, Antonio Iribarren, Jose, Vidal, Francesc, Berenguer, Juan, Gonzalez, Juan, Del Amo, Julia, Jarrin, Inma, Alejos, Belen, Hernando, Victoria, Moreno, Cristina, Iniesta, Carlos, Garcia Sousa, Luis Miguel, Perez, Nieves Sanz, Angeles Munoz-Fernandez, M., Maria Garcia-Merino, Isabel, Consuegra Fernandez, Irene, Gomez Rico, Coral, Gallego de la Fuente, Jorge, Palau Concejo, Paula, Portilla, Joaquin, Merino, Esperanza, Reus, Sergio, Boix, Vicente, Giner, Livia, Gadea, Carmen, Portilla, Irene, Pampliega, Maria, Diez, Marcos, Carlos Rodriguez, Juan, Sanchez-Paya, Jose, Luis Gomez, Juan, Hernandez, Jehovana, Remedios Aleman, Maria, del Mar Alonso, Maria, Inmaculada Hernandez, Maria, Diaz-Flores, Felicitas, Garcia, Dacil, Pelazas, Ricardo, Lopez Lirola, Ana, Sanz Moreno, Jose, Arranz Caso, Alberto, Hernandez Gutierrez, Cristina, Novella Mena, Maria, Pulido, Federico, Bisbal, Otilia, Hernando, Asuncion, Dominguez, Lourdes, Rial Crestelo, David, Bermejo, Laura, Santacreu, Mireia, Arrizabalaga, Julio, Jose Aramburu, Maria, Camino, Xabier, Rodriguez-Arrondo, Francisco, Angel von Wichmann, Miguel, Pascual Tome, Lidia, Angel Goenaga, Miguel, Jesus Bustinduy, Ma, Azkune, Harkaitz, Ibarguren, Maialen, Lizardi, Aitziber, Kortajarena, Xabier, Masia, Mar, Padilla, Sergio, Navarro, Andres, Montolio, Fernando, Robledano, Catalina, Gregori Colome, Joan, Adsuar, Araceli, Pascual, Rafael, Fernandez, Marta, Garcia, Elena, Alberto Garcia, Jose, Barber, Xavier, Bernaldo de Quiros, Juan Carlos Lopez, Gutierrez, Isabel, Ramirez, Margarita, Padilla, Belen, Gijon, Paloma, Aldamiz-Echevarria, Teresa, Tejerina, Francisco, Jose Parras, Francisco, Balsalobre, Pascual, Perez Latorre, Leire, Peraire, Joaquin, Vilades, Consuelo, Veloso, Sergio, Vargas, Montserrat, Lopez-Dupla, Miguel, Olona, Montserrat, Rull, Anna, Rodriguez-Gallego, Esther, Alba, Veronica, Montero Alonso, Marta, Lopez Aldeguer, Jose, Blanes Julia, Marino, Tasias Pitarch, Maria, Castro Hernandez, Ivan, Calabuig Munoz, Eva, Cuellar Tovar, Sandra, Salavert Lleti, Miguel, Fernandez Navarro, Juan, Gonzalez-garcia, Juan, Arnalich, Francisco, Ramon Arribas, Jose, Bernardino de la Serna, Jose Ignacio, Miguel Castro, Juan, Escosa, Luis, Herranz, Pedro, Hontanon, Victor, Garcia-Bujalance, Silvia, Garcia Lopez-Hortelano, Milagros, Gonzalez-Baeza, Alicia, Luz Martin-Carbonero, Maria, Mayoral, Mario, Jose Mellado, Maria, Esteban Mican, Rafael, Montejano, Rocio, Luisa Montes, Maria, Moreno, Victoria, Perez-Valero, Ignacio, Rodes, Berta, Sainz, Talia, Sendagorta, Elena, Stella Alcariz, Natalia, Valencia, Eulalia, Ramon Blanco, Jose, Antonio Oteo, Jose, Ibarra, Valvanera, Metola, Luis, Sanz, Mercedes, Perez-Martinez, Laura, Jaen, Angels, Sanmarti, Montse, Cairo, Mireia, Martinez-Lacasa, Javier, Velli, Pablo, Font, Roser, Xercavins, Mariona, Alonso, Noemi, Rivero, Maria, Reparaz, Jesus, Ruiz de Alda, Maria Gracia, de Leon Cano, Maria Teresa, Ruiz de Galarreta, Beatriz Pierola, Segura, Ferran, Jose Amengual, Maria, Navarro, Gemma, Sala, Montserrat, Cervantes, Manuel, Pineda, Valentin, Calzado, Sonia, Navarro, Marta, de los Santos, Ignacio, Sanz Sanz, Jesus, Salas Aparicio, Ana, Sarria Cepeda, Cristina, Garcia-Fraile Fraile, Lucio, Martin Gayo, Enrique, Luis Casado, Jose, Dronda, Fernando, Moreno, Ana, Perez Elias, Maria Jesus, Gomez Ayerbe, Cristina, Gutierrez, Carolina, Madrid, Nadia, del Campo Terron, Santos, Marti, Paloma, Ansa, Uxua, Serrano, Sergio, Jesus Vivancos, Maria, Bernal, Enrique, Cano, Alfredo, Alcaraz Garcia, Antonia, Bravo Urbieta, Joaquin, Munoz, Angeles, Jose Alcaraz, Maria, del Carmen Villalba, Maria, Hernandez, Jose, Pena, Alejandro, Munoz, Leopoldo, Casas, Paz, Alvarez, Marta, Chueca, Natalia, Vinuesa, David, Martinez-Montes, Clara, Del Romero, Jorge, Rodriguez, Carmen, Puerta, Teresa, Carlos Carrio, Juan, Vera, Mar, Ballesteros, Juan, Ayerdi, Oskar, Riera, Melchor, Penaranda, Maria, Leyes, Maria, Angels Ribas, Ma, Campins, Antoni A., Vidal, Carmen, Fanjul, Francisco, Murillas, Javier, Homar, Francisco, Santos, Jesus, Gomez Ayerbe, Crisitina, Viciana, Isabel, Palacios, Rosario, Maria Gonzalez, Carmen, Espinosa, Nuria, Fernando Lopez-Cortes, Luis, Podzamczer, Daniel, Ferrer, Elena, Imaz, Arkaitz, Tiraboschi, Juan, Silva, Ana, Saumoy, Maria, Olalla, Julian, del Arco, Alfonso, de la Torre, Javier, Luis Prada, Jose, de Lomas Guerrero, Jose Maria Garcia, Perez Stachowski, Javier, Juan Martinez, Onofre, Jesus Vera, Francisco, Martinez, Lorena, Garcia, Josefina, Alcaraz, Begona, Jimeno, Amaya, Castro Iglesias, Angeles, Pernas Souto, Berta, Mena de Cea, Alvaro, Galera, Carlos, Albendin, Helena, Perez, Aurora, Iborra, Asuncion, Moreno, Antonio, Angustias Merlos, Maria, Vidal, Asuncion, Suarez-Garcia, Ines, Malmierca, Eduardo, Gonzalez-Ruano, Patricia, Martin Rodrigo, Dolores, Omar Mohamed-Balghata, Mohamed, Gomez Vidal, Maria Amparo, Estrada Perez, Vicente, Tellez Molina, Maria Jesus, Vergas Garcia, Jorge, Perez-Somarriba Moreno, Juncal, Gorgolas, Miguel, Cabello, Alfonso, Alvarez, Beatriz, Prieto, Laura, Galindo Puerto, Maria Jose, Fernando Vilalta, Ramon, Ferrer Ribera, Ana, Rivero Roman, Antonio, Brieva Herrero, Maria Teresa, Rivero Juarez, Antonio, Lopez Lopez, Pedro, Machuca Sanchez, Isabel, Pena Martinez, Jose, Cervero Jimenez, Miguel, Torres Perea, Rafael, Jusdado Ruiz-Capillas, Juan Jose, Pineda, Juan A., CoRIS, Spanish HIV HGM BioBank, LTNPs Cohort, Red de Investigación Cooperativa en Investigación en Sida (España), Instituto de Salud Carlos III, and Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)

Subjects
Oncology, medicine.medical_specialty, LTNPs, lcsh:Medicine, Single-nucleotide polymorphism, non-progression, 030312 virology, Calcitriol receptor, 03 medical and health sciences, single nucleotide polymorphisms, Acquired immunodeficiency syndrome (AIDS), Internal medicine, medicine, Vitamin D and neurology, SNP, Allele, 030304 developmental biology, VDR, Non-progression, 0303 health sciences, business.industry, Brief Report, lcsh:R, General Medicine, Odds ratio, Single nucleotide polymorphisms, Acquired immune system, medicine.disease, AIDS, business
Abstract

Background: Vitamin D is a fundamental regulator of host defenses by activating genes related to innate and adaptive immunity. In this study, we analyzed the association among single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) gene, with clinical patterns of AIDS progression in antiretroviral treatment (ART)-naive HIV-infected patients. Methods: We conducted a retrospective study in 667 HIV-infected patients, who were classified within three groups according to their AIDS progression pattern (183 long-term non-progressors (LTNPs), 334 moderate progressors (MPs), and 150 rapid progressors (RPs)). Five VDR SNPs (rs11568820, rs4516035, rs2228570, rs1544410, and rs7975232) were genotyped using Agena Bioscience's MassARRAY platform. Results: Significant association results were found for rs2228570. Within all HIV patients, the presence of T allele at VDR rs2228570 SNP was protective against AIDS progression (ordinal outcome) under additive (adjusted odds ratio (aOR) = 0.75; p = 0.009), dominant (aOR = 0.69; p = 0.015), and codominant (aOR = 0.56; p = 0.017) inheritance models. In addition, the same allele was protective under additive and codominant inheritance models when we compared with LTNPs vs. RPs [aOR = 0.64 (p = 0.019) and aOR = 0.37 (p = 0.018), respectively] and when we compared MPs vs. RPs [aOR = 0.72 (p = 0.035) and aOR = 0.45 (p = 0.028), respectively]. Conclusions: The VDR rs2228570 T allele was related to a lower AIDS progression pattern in ART-naive HIV-infected patients. These findings expand upon the knowledge about HIV pathogenesis in untreated HIV-infected patients with different clinical outcomes., This work has been (partially) funded by the RD16/0025/0019 and RD16CIII/0002/0002, projects as part of Accion Estrategica en Salud, Plan Nacional de Investigacion Cientifica, Desarrollo e Innovacion Tecnologica (2013-2016) and cofinanced by Instituto de Salud Carlos III (Subdireccion General de Evaluacion) and Fondo Europeo de Desarrollo Regional (FEDER), RETIC PT17/0015/0042, Fondo de Investigacion Sanitaria (FIS) (grant number PI16/01863, PI17/01115, PI17CIII/00003), EPIICAL Project and Comunidad de Madrid B2017/BMD-3703. Programa de Investigacion de la Consejeria de Sanidad de la Comunidad de Madrid to JLJ. CIBER-BBN is an initiative funded by the VI National R& D& i Plan 2008-2011, Iniciativa Ingenio 2010, the Consolider Program, and CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund. COST CA17140 Cancer Nanomedicine-Front the Bench to Bebside. AFR are supported and funded by Instituto de Salud Carlos III [grant number CP14/0010].

Published
2019

44. Ciprofloxacin prophylaxis in patients with acute leukemia and granulocytopenia in an area with a high prevalence of ciprofloxacin-resistant Escherichia coli

Author

Gomez, Lucia, Garau, Javier, Estrada, Cristina, Marquez, Montserrat, Dalmau, David, Xercavins, Mariona, Marti, Josep Maria, and Estany, Cristina

Subjects
Oncology, Experimental -- Analysis, Cancer patients -- Health aspects, Cancer patients -- Care and treatment, Cancer patients -- Drug therapy, Acute leukemia -- Health aspects, Acute leukemia -- Care and treatment, Acute leukemia -- Drug therapy, Ciprofloxacin -- Physiological aspects, Agranulocytosis -- Health aspects, Agranulocytosis -- Care and treatment, Granulocytopenia, Drug resistance -- Analysis, Drug resistance -- Physiological aspects, Escherichia coli -- Physiological aspects, Health
Published
2003

46. A Multinational, Preregistered Cohort Study of β-Lactam/β-Lactamase Inhibitor Combinations for Treatment of Bloodstream Infections Due to Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

Author

Belén Gutiérrez Gutiérrez, Salvador Pérez Galera, Elena Salamanca, Marina de Cueto, Esther Calbo, Benito Almirante, VIALE, PIERLUIGI, Antonio Oliver, Vicente Pintado, Oriol Gasch, Luis Martínez Martínez, Johann Pitout, Murat Akova, Carmen Peña, José Molina, Alicia Hernández, Mario Venditti, Nuria Prim, Julia Origüen, German Bou, Evelina Tacconelli, Mario Tumbarello, Axel Hamprecht, Helen Giamarellou, Manel Almela, Federico Pérez, Mitchell J. Schwaber, Joaquín Bermejo, Warren Lowman, Po Ren Hsueh, Marta Mora Rillo, Clara Natera, Maria Souli, Robert A. Bonomo, Yehuda Carmeli, David L. Paterson, Alvaro Pascual, Jesús Rodríguez Baño, the REIPI/ESGBIS/INCREMENT Group [, Gálvez, J., Del Toro, M. D., Retamar, P., Falcone, M., Russo, A., Daikos, G., Karaiskos, I., Trecarichi, E. M., Losito, A. R., Paterson, D. L., García Vázquez, E., Gómez, J., Roilides, E., Iosifidis, E., Doi, Y., Tuon, F. F., Navarro, F., Mirelis, B., San Juan, R., Fernández Ruiz, M., Larrosa, N., Puig, M., Cisneros, J. M., González, V., Rucci, Victoria, Ruiz De Gopegui, E., Marinescu, C. I., Fariñas, M. C., Cano, M. E., Gozalo, M., Paño Pardo, J. R., Navarro San Francisco, C., Gómez Zorrilla, S., Tubau, F., Pournaras, S., Tsakris, A., Zarkotou, O., Azap, Ö. K., Antoniadou, A., Poulakou, G., Virmani, D., Torre Cisneros, J., Pérez Nadales, E., Gracia Ahulfinger, I., Helvaci, Ö., Sahin, A. O., Cantón, R., Ruiz, P., BARTOLETTI, MICHELE, GIANNELLA, MADDALENA, Riemenschneider, F., Badia, C., Xercavins, Mariona, Fontanals, D., Jové, E., Belén Gutiérrez-Gutiérrez, Salvador Pérez-Galera, Elena Salamanca, Marina de Cueto, Esther Calbo, Benito Almirante, Pierluigi Viale, Antonio Oliver, Vicente Pintado, Oriol Gasch, Luis Martínez-Martínez, Johann Pitout, Murat Akova, Carmen Peña, José Molina, Alicia Hernández, Mario Venditti, Nuria Prim, Julia Origüen, German Bou, Evelina Tacconelli, Mario Tumbarello, Axel Hamprecht, Helen Giamarellou, Manel Almela, Federico Pérez, Mitchell J. Schwaber, Joaquín Bermejo, Warren Lowman, Po-Ren Hsueh, Marta Mora-Rillo, Clara Natera, Maria Souli, Robert A. Bonomo, Yehuda Carmeli, David L. Paterson, Alvaro Pascual, Jesús Rodríguez-Baño, the REIPI/ESGBIS/INCREMENT Group [, Gálvez, J., Del Toro, M.D., Retamar, P., Falcone, M., Russo, A., Daikos, G., Karaiskos, I., Trecarichi, E.M., Losito, A.R., Paterson, D.L., García-Vázquez, E., Gómez, J., Roilides, E., Iosifidis, E., Doi, Y., Tuon, F.F., Navarro, F., Mirelis, B., San Juan, R., Fernández-Ruiz, M., Larrosa, N., Puig, M., Cisneros, J.M., González, V., Rucci, Victoria, Ruiz De Gopegui, E., Marinescu, C.I., Fariñas, M.C., Cano, M.E., Gozalo, M., Paño-Pardo, J.R., Navarro-San Francisco, C., Gómez-Zorrilla, S., Tubau, F., Pournaras, S., Tsakris, A., Zarkotou, O., Azap, Ö.K., Antoniadou, A., Poulakou, G., Virmani, D., Torre-Cisneros, J., Pérez-Nadales, E., Gracia-Ahulfinger, I., Helvaci, Ö., Sahin, A.O., Cantón, R., Ruiz, P., Bartoletti, M., Giannella, M., Riemenschneider, F., Badia, C., Xercavins, Mariona, Fontanals, D., Jové, E., ], Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, European Commission, Red Española de Investigación en Patología Infecciosa, European Federation of Pharmaceutical Industries and Associations, Cuyahoga County Veterans Service Commission, Geriatric Research Education and Clinical Center (US), National Institute of Allergy and Infectious Diseases (US), National Institutes of Health (US), Peña, Carmen [0000-0002-6673-2883], Peña, Carmen, İç Hastalıkları, Universidad de Sevilla. Departamento de Microbiología, Universidad de Sevilla. Departamento de Medicina, and European Union (UE). FP7

Subjects
0301 basic medicine, Male, Carbapenem, medicine.medical_specialty, Pediatrics, 030106 microbiology, Infectious Disease, Bacteremia, Kaplan-Meier Estimate, Clinical Therapeutics, Settore MED/17 - MALATTIE INFETTIVE, beta-Lactams, Microbiology, beta-Lactamases, 03 medical and health sciences, 0302 clinical medicine, Aged, Anti-Bacterial Agents, Carbapenems, Enterobacteriaceae, Female, Humans, Middle Aged, Multivariate Analysis, Odds Ratio, Retrospective Studies, beta-Lactamase Inhibitors, Internal medicine, medicine, Pharmacology (medical), 030212 general & internal medicine, Pharmacology & Pharmacy, Beta-Lactamase Inhibitors, Pharmacology, business.industry, Mortality rate, Retrospective cohort study, Odds ratio, bacterial infections and mycoses, Confidence interval, 3. Good health, Infectious Diseases, Cohort, business, medicine.drug, Cohort study
Abstract

The spread of extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) is leading to increased carbapenem consumption. Alternatives to carbapenems need to be investigated. We investigated whether β-lactam/β-lactamase inhibitor (BLBLI) combinations are as effective as carbapenems in the treatment of bloodstream infections (BSI) due to ESBL-E. A multinational, retrospective cohort study was performed. Patients with monomicrobial BSI due to ESBL-E were studied; specific criteria were applied for inclusion of patients in the empirical-therapy (ET) cohort (ETC; 365 patients), targeted-therapy (TT) cohort (TTC; 601 patients), and global cohort (GC; 627 patients). The main outcome variables were cure/improvement rate at day 14 and all-cause 30-day mortality. Multivariate analysis, propensity scores (PS), and sensitivity analyses were used to control for confounding. The cure/improvement rates with BLBLIs and carbapenems were 80.0% and 78.9% in the ETC and 90.2% and 85.5% in the TTC, respectively. The 30-day mortality rates were 17.6% and 20% in the ETC and 9.8% and 13.9% in the TTC, respectively. The adjusted odds ratio (OR) (95% confidence interval [CI]) values for cure/improvement rate with ET with BLBLIs were 1.37 (0.69 to 2.76); for TT, they were 1.61 (0.58 to 4.86). Regarding 30-day mortality, the adjusted OR (95% CI) values were 0.55 (0.25 to 1.18) for ET and 0.59 (0.19 to 1.71) for TT. The results were consistent in all subgroups studied, in a stratified analysis according to quartiles of PS, in PS-matched cases, and in the GC. BLBLIs, if active in vitro, appear to be as effective as carbapenems for ET and TT of BSI due to ESLB-E regardless of the source and specific species. These data may help to avoid the overuse of carbapenems. (This study has been registered at ClinicalTrials.gov under registration no. NCT01764490.), The work was funded by the Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, cofinanced by European Development Regional Fund titled A Way To Achieve Europe ERDF, the Spanish Network for Research in Infectious Diseases (REIPI RD12/0015), and FIS (PI10/02021). Participants in the study received support for research from the Innovative Medicines Initiative Joint Undertaking under the Combatting Bacterial Resistance in Europe—Molecule against Gram Negative Infections (COMBACTE-MAGNET) agreement 115737 resources, which are composed of financial contributions from the European Union's Seventh Framework Programme (FP7/2007-2013) and the European Federation of Pharmaceutical Industries and Associations (EFPIA) companies' in kind contributions (A. Pascua and J. Rodríguez-Baño), the Cleveland Department of Veterans Affairs, the Veterans Affairs Merit Review Program, the Geriatric Research Education and Clinical Center VISN 10 (VISN 10 GRECC), and NIAID, NIH, under award numbers R01AI072219 and R01AI063517 (R. A. Bonomo).

Published
2016

47. Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors

Author

Alejos, Belen, Suarez-Garcia, Ines, Bisbal, Otilia, Antonio Iribarren, Jose, Asensi, Victor, Gorgolas, Miguel, Muga, Roberto, Moreno, Santiago, Jarrin, Inma, Dalmau, David, Luisa Navarro, Maria, Isabel Gonzalez, Maria, Luis Blanco, Jose, Garcia, Federico, Rubio, Rafael, Gutierrez, Felix, Vidal, Francesc, Berenguer, Juan, Gonzalez, Juan, Hernando, Victoria, Moreno, Cristina, Iniesta, Carlos, Garcia Sousa, Luis Miguel, Sanz Perez, Nieves, Angeles Munoz-Fernandez, M., Maria Garcia-Merino, Isabel, Consuegra Fernandez, Irene, Gomez Rico, Coral, Gallego De la Fuente, Jorge, Palau Concejo, Paula, Portilla, Joaquin, Merino, Esperanza, Reus, Sergio, Boix, Vicente, Giner, Livia, Gadea, Carmen, Portilla, Irene, Pampliega, Maria, Diez, Marcos, Carlos Rodriguez, Juan, Sanchez-Paya, Jose, Luis Gomez, Juan, Hernandez, Jehovana, Remedios Aleman, Maria, del Mar Alonso, Maria, Inmaculada Hernandez, Maria, Diaz-Flores, Felicitas, Garcia, Dacil, Pelazas, Ricardo, Lopez Lirola, Ana, Sanz Moreno, Jose, Arranz Caso, Alberto, Hernandez Gutierrez, Cristina, Novella Mena, Maria, Pulido, Federico, Hernando, Asuncion, Dominguez, Lourdes, Rial Crestelo, David, Bermejo, Laura, Santacreu, Mireia, Arrizabalaga, Julio, Jose Aramburu, Maria, Camino, Xabier, Rodriguez-Arrondo, Francisco, Angel von Wichmann, Miguel, Pascual Tome, Lidia, Angel Goenaga, Miguel, Jesus Bustin-Duy, Ma, Azkune, Harkaitz, Ibarguren, Maialen, Lizardi, Aitziber, Kortajarena, Xabier, Masia, Mar, Padilla, Sergio, Navarro, Andres, Montolio, Fernando, Robledano, Catalina, Gregori Colome, Joan, Adsuar, Araceli, Pascual, Rafael, Fernandez, Marta, Garcia, Elena, Alberto Garcia, Jose, Barber, Xavier, Sanvisens, Arantza, Fuster, Daniel, Lopez Bernaldo de Quiros, Juan Carlos, Gutierrez, Isabel, Ramirez, Margarita, Padilla, Belen, Gijon, Paloma, Aldamiz-Echevarria, Teresa, Tejerina, Francisco, Jose Parras, Francisco, Balsalobre, Pascual, Diez, Cristina, Perez Latorre, Leire, Peraire, Joaquin, Vilades, Consuelo, Veloso, Sergio, Vargas, Montserrat, Lopez-Dupla, Miguel, Olona, Montserrat, Rull, Anna, Rodriguez-Gallego, Esther, Alba, Veronica, Montero Alonso, Marta, Lopez Aldeguer, Jose, Blanes Julia, Marino, Tasias Pitarch, Maria, Castro Hernandez, Ivan, Calabuig Munoz, Eva, Cuellar Tovar, Sandra, Salavert Lleti, Miguel, Fernandez Navarro, Juan, Gonzalez-garcia, Juan, Arnalich, Francisco, Ramon Arribas, Jose, Bernardino de la Serna, Jose Ignacio, Miguel Castro, Juan, Escosa, Luis, Herranz, Pedro, Hontanon, Victor, Garcia-Bujalance, Silvia, Garcia Lopez-Hortelano, Milagros, Gonzalez-Baeza, Alicia, Luz Martin-Carbonero, Maria, Mayoral, Mario, Jose Mellado, Maria, Esteban Mican, Rafael, Montejano, Rocio, Luisa Montes, Maria, Moreno, Victoria, Perez-Valero, Ignacio, Rodes, Berta, Sainz, Talia, Sendagorta, Elena, Stella Alcariz, Natalia, Valencia, Eulalia, Ramon Blanco, Jose, Antonio Oteo, Jose, Ibarra, Valvanera, Metola, Luis, Sanz, Mercedes, Perez-Martinez, Laura, Arazo, Piedad, Samperiz, Gloria, Jaen, Angels, Sanmarti, Montse, Cairo, Mireia, Martinez-Lacasa, Javier, Velli, Pablo, Font, Roser, Xercavins, Mariona, Alonso, Noemi, Rivero, Maria, Reparaz, Jesus, Gracia Ruiz de Alda, Maria, de Leon Cano, Maria Teresa, Pierola Ruiz de Galarreta, Beatriz, Segura, Ferran, Jose Amengual, Maria, Navarro, Gemma, Sala, Montserrat, Cervantes, Manuel, Pineda, Valentin, Calzado, Sonia, Navarro, Marta, de los Santos, Ignacio, Sanz Sanz, Jesus, Salas Aparicio, Ana, Sarria Cepeda, Cristina, Garcia-Fraile Fraile, Lucio, Martin Gayo, Enrique, Luis Casado, Jose, Dronda, Fernando, Moreno, Ana, Perez Elias, Maria Jesus, Gomez Ayerbe, Cristina, Gutierrez, Carolina, Madrid, Nadia, del Campo Terron, Santos, Marti, Paloma, Ansa, Uxua, Serrano, Sergio, Jesus Vivancos, Maria, Bernal, Enrique, Cano, Alfredo, Alcaraz Garcia, Antonia, Bravo Urbieta, Joaquin, Munoz, Angeles, Jose Alcaraz, Maria, del Carmen Villalba, Maria, Hernandez, Jose, Pena, Alejandro, Munoz, Leopoldo, Casas, Paz, Alvarez, Marta, Chueca, Natalia, Vinuesa, David, Martinez-Montes, Clara, Del Romero, Jorge, Rodriguez, Carmen, Puerta, Teresa, Carlos Carrio, Juan, Vera, Mar, Ballesteros, Juan, Ayerdi, Oskar, Antela, Antonio, Losada, Elena, Riera, Melchor, Penaranda, Maria, Leyes, Maria, Angels Ribas, Ma, Campins, Antoni A., Vidal, Carmen, Fanjul, Francisco, Murillas, Javier, Homar, Francisco, Santos, Jesus, Gomez Ayerbe, Crisitina, Viciana, Isabel, Palacios, Rosario, Maria Gonzalez, Carmen, Viciana, Pompeyo, Espinosa, Nuria, Fernando Lopez-Cortes, Luis, Podzamczer, Daniel, Ferrer, Elena, Imaz, Arkaitz, Tiraboschi, Juan, Silva, Ana, Saumoy, Maria, Ribera, Esteban, Curran, Adrian, Olalla, Julian, del Arco, Alfonso, de la Torre, Javier, Luis Prada, Jose, de Lomas Guerrero, Jose Maria Garcia, Perez Stachowski, Javier, Juan Martinez, Onofre, Jesus Vera, Francisco, Martinez, Lorena, Garcia, Josefina, Alcaraz, Begona, Jimeno, Amaya, Castro Iglesias, Angeles, Pernas Souto, Berta, Mena de Cea, Alvaro, Munoz, Josefa, Zurine Zubero, Miren, Mirena Baraia-Etxaburu, Josu, Ibarra Ugarte, Sofia, Ferrero Beneitez, Oscar Luis, Lopez de Munain, Josefina, Camara Lopez, Ma Mar, de la Pena, Mireia, Lopez, Miriam, Galera, Carlos, Albendin, Helena, Perez, Aurora, Iborra, Asuncion, Moreno, Antonio, Angustias Merlos, Maria, Vidal, Asuncion, Amador, Concha, Pasquau, Francisco, Ena, Javier, Benito, Concha, Fenoll, Vicenta, Gil Anguita, Concepcion, Algado Rabasa, Jose Tomas, Malmierca, Eduardo, Gonzalez-Ruano, Patricia, Martin Rodrigo, Dolores, Ruiz Seco, Ma Pilar, Omar Mohamed-Balghata, Mohamed, Gomez Vidal, Maria Amparo, Alberto de Zarraga, Miguel, Estrada Perez, Vicente, Tellez Molina, Maria Jesus, Vergas Garcia, Jorge, Perez-Somarriba Moreno, Juncal, Cabello, Alfonso, Alvarez, Beatriz, Prieto, Laura, Galindo Puerto, Maria Jose, Fernando Vilalta, Ramon, Ferrer Ribera, Ana, Rivero Roman, Antonio, Brieva Herrero, Maria Teresa, Rivero Juarez, Antonio, Lopez Lopez, Pedro, Machuca Sanchez, Isabel, Pena Martinez, Jose, Cervero Jimenez, Miguel, Torres Perea, Rafael, Jusdado Ruiz-Capillas, Juan Jose, Pineda, Juan A., CoRIS Cohort, Instituto de Salud Carlos III, Red Española de Investigación en SIDA, European Commission, ViiV Healthcare, Red de Investigación Cooperativa en Investigación en Sida (España), and Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)

Subjects
Male, European People, Spanish People, Health Care Providers, Pathology and Laboratory Medicine, seropositividad al VIH, Geographical locations, 0302 clinical medicine, Immunodeficiency Viruses, Abacavir, HIV Seropositivity, Odds Ratio, Ethnicities, Public and Occupational Health, mediana edad, Antiretrovirals, adulto, cociente de probabilidades relativas, antirretrovirales, Anti-Retroviral Agents, Medical Microbiology, Viral Pathogens, Medicine, medicine.medical_specialty, Sida, Science, Immunology, 030106 microbiology, Investigación médica, Men WHO Have Sex with Men, Integrase Inhibitors, Microbiology, Tenofovir alafenamide, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Physicians, Humans, Microbial Pathogens, Pharmacology, Organisms, Biology and Life Sciences, Raltegravir, Health Care, Regimen, chemistry, Population Groupings, Preventive Medicine, Sexuality Groupings, RNA viruses, 0301 basic medicine, Medical Doctors, humanos, Tratamiento médico, chemistry.chemical_compound, Antiretroviral Therapy, Highly Active, Medicine and Health Sciences, Medical Personnel, 030212 general & internal medicine, Hispanic People, Multidisciplinary, Antimicrobials, Cobicistat, Drugs, Viral Load, Middle Aged, Antivirals, Vaccination and Immunization, Europe, Professions, Rilpivirine, Viruses, Female, Pathogens, inhibidores de la integrasa, Research Article, medicine.drug, Adult, Antiretroviral Therapy, Emtricitabine, Antiviral Therapy, Microbial Control, Virology, Internal medicine, Retroviruses, medicine, European Union, análisis multifactorial, business.industry, Lentivirus, HIV, Spain, People and Places, Multivariate Analysis, Ritonavir, business, Viral Transmission and Infection
Abstract

CoRIS cohort., [Background] We aimed to describe the most frequently prescribed initial antiretroviral therapy (ART) regimens in recent years in HIV-positive persons in the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) and to investigate factors associated with the choice of each regimen., [Methods] We analyzed initial ART regimens prescribed in adults participating in CoRIS from 2014 to 2017. Only regimens prescribed in >5% of patients were considered. We used multivariable multinomial regression to estimate Relative Risk Ratios (RRRs) for the association between sociodemographic and clinical characteristics and the choice of the initial regimen., [Results] Among 2874 participants, abacavir(ABC)/lamivudine(3TC)/dolutegavir(DTG) was the most frequently prescribed regimen (32.1%), followed by tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC)/elvitegravir(EVG)/cobicistat(COBI) (14.9%), TDF/FTC/rilpivirine (RPV) (14.0%), tenofovir alafenamide (TAF)/FTC/EVG/COBI (13.7%), TDF/FTC+DTG (10.0%), TDF/FTC+darunavir/ritonavir or darunavir/cobicistat (bDRV) (9.8%) and TDF/FTC+raltegravir (RAL) (5.6%). Compared with ABC/3TC/DTG, starting TDF/FTC/RPV was less likely in patients with CD4100.000 copies/mL. TDF/FTC+DTG was more frequent in those with CD4100.000 copies/mL. TDF/FTC+RAL and TDF/FTC+bDRV were also more frequent among patients with CD4, [Conclusions] The choice of initial ART regimens is consistent with Spanish guidelines’ recommendations, but is also clearly influenced by physician’s perception based on patient’s clinical and sociodemographic variables and by the prescribing hospital location., The RIS cohort (CoRIS) is supported by the Instituto de Salud Carlos III through the Red Temática de Investigación Cooperativa en Sida (RD06/006, RD12/0017/0018 and RD16/0002/0006) as part of the Plan Nacional I+D+i and cofinanced by ISCIII-Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER). This study was funded by ViiV Healthcare.

Published
2019
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48. Assessment of Quality Indicators for Appropriate Antibiotic Use

Author

Arcenillas, Paula, primary, Boix-Palop, Lucía, additional, Gómez, Lucía, additional, Xercavins, Mariona, additional, March, Pablo, additional, Martinez, Laura, additional, Riera, Montserrat, additional, Madridejos, Rosa, additional, Badia, Cristina, additional, Nicolás, Jordi, additional, and Calbo, Esther, additional

Published
2018
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50. Prevalence of Colorectal Neoplasms Among Patients With Enterococcus faecalisEndocarditis in the GAMES Cohort (2008–2017)

Author

Pericàs, Juan M., Ambrosioni, Juan, Muñoz, Patricia, de Alarcón, Arístides, Kestler, Martha, Mari-Hualde, Amaia, Moreno, Asunción, Goenaga, Miguel Á., Fariñas, M. Carmen, Rodríguez-Álvarez, Regino, Ojeda-Burgos, Guillermo, Gálvez-Acebal, Juan, Hidalgo-Tenorio, Carmen, Noureddine, Mariam, Miró, José M., Sánchez, Fernando Fernández, Noureddine, Mariam, Rosas, Gabriel, Lima, Javier de la Torre, Blanco, Roberto, Boado, María Victoria, Lázaro, Marta Campaña, Crespo, Alejandro, Goikoetxea, Josune, Iruretagoyena, José Ramón, Zuazabal, Josu Irurzun, López-Soria, Leire, Montejo, Miguel, Nieto, Javier, Rodrigo, David, Rodríguez, Regino, Vitoria, Yolanda, Voces, Roberto, López, Ma Victoria García, Georgieva, Radka Ivanova, Ojeda, Guillermo, Bailón, Isabel Rodríguez, Morales, Josefa Ruiz, Cuende, Ana María, Echeverría, Tomás, Fuerte, Ana, Gaminde, Eduardo, Goenaga, Miguel Ángel, Idígoras, Pedro, Iribarren, José Antonio, Yarza, Alberto Izaguirre, Urkola, Xabier Kortajarena, Reviejo, Carlos, Carrasco, Rafael, Climent, Vicente, Llamas, Patricio, Merino, Esperanza, Plazas, Joaquín, Reus, Sergio, Álvarez, Nemesio, Bravo-Ferrer, José María, Castelo, Laura, Cuenca, José, Llinares, Pedro, Rey, Enrique Miguez, Mayo, María Rodríguez, Sánchez, Efrén, Regueiro, Dolores Sousa, Martínez, Francisco Javier, del Mar Alonso, Ma, Castro, Beatriz, Rosado, Dácil García, del Carmen Durán, Ma, Gómez, Ma Antonia Miguel, Lacalzada, Juan, Nassar, Ibrahim, Ciezar, Antonio Plata, Iglesias, José Ma Reguera, Álvarez, Víctor Asensi, Costas, Carlos, Hera, Jesús de la, Suárez, Jonnathan Fernández, Fraile, Lisardo Iglesias, Arguero, Víctor León, Menéndez, José López, Bajo, Pilar Mencia, Morales, Carlos, Torrico, Alfonso Moreno, Palomo, Carmen, Martínez, Begoña Paya, Esteban, Ángeles Rodríguez, García, Raquel Rodríguez, Asensio, Mauricio Telenti, Almela, Manuel, Ambrosioni, Juan, Azqueta, Manuel, Brunet, Mercè, Bodro, Marta, Cartañá, Ramón, Falces, Carlos, Fita, Guillermina, Fuster, David, García de la Mària, Cristina, García-Pares, Delia, Hernández-Meneses, Marta, Pérez, Jaume Llopis, Marco, Francesc, Miró, José M., Moreno, Asunción, Nicolás, David, Ninot, Salvador, Quintana, Eduardo, Paré, Carlos, Pereda, Daniel, Pericás, Juan M., Pomar, José L., Ramírez, José, Rovira, Irene, Sandoval, Elena, Sitges, Marta, Soy, Dolors, Téllez, Adrián, Tolosana, José M., Vidal, Bárbara, Vila, Jordi, Adán, Iván, Bermejo, Javier, Bouza, Emilio, Celemín, Daniel, Caballero, Gregorio Cuerpo, Montero, Antonia Delgado, Mansilla, Ana García, Leoni, Ma Eugenia García, Ramallo, Víctor González, Hernández, Martha Kestler, Hualde, Amaia Mari, Marín, Mercedes, Martínez-Sellés, Manuel, Muñoz, Patricia, Rincón, Cristina, Rodríguez-Abella, Hugo, Rodríguez-Créixems, Marta, Pinilla, Blanca, Pinto, Ángel, Valerio, Maricela, Vázquez, Pilar, Moreno, Eduardo Verde, Antorrena, Isabel, Loeches, Belén, Quirós, Alejandro Martín, Moreno, Mar, Ramírez, Ulises, Bastón, Verónica Rial, Romero, María, Saldaña, Araceli, Balbín, Jesús Agüero, Castillo, Carlos Armiñanzas, Arnaiz, Ana, de las Revillas, Francisco Arnaiz, Belaustegui, Manuel Cobo, Fariñas, María Carmen, Fariñas-Álvarez, Concepción, Izquierdo, Rubén Gómez, García, Iván, Rico, Claudia González, Gutiérrez-Cuadra, Manuel, Díez, José Gutiérrez, Pajarón, Marcos, Parra, José Antonio, Teira, Ramón, Zarauza, Jesús, Calderón Parra, Jorge, Cobo, Marta, Domínguez, Fernando, Fortaleza, Alberto, Pavía, Pablo García, González, Jesús, Cruz, Ana Fernández, Múñez, Elena, Ramos, Antonio, Romero, Isabel Sánchez, Centella, Tomasa, Hermida, José Manuel, Moya, José Luis, Martín-Dávila, Pilar, Navas, Enrique, Oliva, Enrique, Río, Alejandro del, Rodríguez-Roda Stuart, Jorge, Ruiz, Soledad, Tenorio, Carmen Hidalgo, Delia, Manuel Almendro, Araji, Omar, Barquero, José Miguel, Jambrina, Román Calvo, de Cueto, Marina, Acebal, Juan Gálvez, Méndez, Irene, Morales, Isabel, López-Cortés, Luis Eduardo, de Alarcón, Arístides, García, Emilio, Haro, Juan Luis, Lepe, José Antonio, López, Francisco, Luque, Rafael, Alonso, Luis Javier, Azcárate, Pedro, Azcona Gutiérrez, José Manuel, Blanco, José Ramón, Villegas, Antonio Cabrera, García-Álvarez, Lara, Oteo, José Antonio, Sanz, Mercedes, de Benito, Natividad, Gurguí, Mercé, Pacho, Cristina, Pericas, Roser, Pons, Guillem, Álvarez, M., Fernández, A.L., Martínez, Amparo, Prieto, A., Regueiro, Benito, Tijeira, E., Vega, Marino, Blasco, Andrés Canut, Mollar, José Cordo, Gainzarain Arana, Juan Carlos, Uriarte, Oscar García, López, Alejandro Martín, Ortiz de Zárate, Zuriñe, Urturi Matos, José Antonio, Gloria, García-Domínguez, Antonio, Sánchez-Porto, Leal, José Ma Arribas, Vázquez, Elisa García, Torres, Alicia Hernández, Blázquez, Ana, Valenzuela, Gonzalo de la Morena, Alonso, Ángel, Aramburu, Javier, Calvo, Felicitas Elena, Rodríguez, Anai Moreno, Tarabini-Castellani, Paola, Gálvez, Eva Heredero, Bellido, Carolina Maicas, Pau, José Largo, Sepúlveda, Ma Antonia, Sierra, Pilar Toledano, Iqbal-Mirza, Sadaf Zafar, Alcolea, Eva Cascales, Yañez, Ivan Keituqwa, Martínez, Julián Navarro, Ballesta, Ana Peláez, Escobar, Eduardo Moreno, Monje, Alejandro Peña, Cabrera, Valme Sánchez, García, David Vinuesa, Asenjo, María Arrizabalaga, Luna, Carmen Cifuentes, Morcillo, Juana Núñez, Seco, Ma Cruz Pérez, Gelabert, Aroa Villoslada, Guallar, Carmen Aured, Abad, Nuria Fernández, Mangas, Pilar García, Adell, Marta Matamala, Ruiz, Ma Pilar Palacián, Porres, Juan Carlos, Vidal, Begoña Alcaraz, Trigueros, Nazaret Cobos, Del Amor Espín, María Jesús, Giner Caro, José Antonio, Sánchez, Roberto Jiménez, Almazán, Amaya Jimeno, Freire, Alejandro Ortín, González, Monserrat Viqueira, Ramis, Pere Pericás, Blanco, Ma Ángels Ribas, Ruiz de Gopegui Bordes, Enrique, Bonet, Laura Vidal, Munera, Ma Carmen Bellón, Garaizabal, Elena Escribano, Martínez, Antonia Tercero, Segura Luque, Juan Carlos, Badía, Cristina, Palop, Lucía Boix, Xercavins, Mariona, Eloy Gómez Nebreda, Sónia Ibars., Herrera, Ibalia Horcajada, Gallego Héctor Marrero Santiago, Irene Menduiña, de Miguel Martínez, Isabel, and Álamo, Elena Pisos

Abstract

To investigate the rate of colorectal neoplasms (CRNs) in patients who have Enterococcus faecalisinfective endocarditis (EFIE) with available colonoscopies and to assess whether this is associated with the identification of a focus the infection.

Published
2021
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