Search

We studied the 2018 outburst of the black hole transient H 1743 − 322 with a series of Insight-HXMT, NICER, and NuSTAR observations, covering the 1–120 keV band. With our broad-band X-ray spectral modelling, we confirm that the source remained in the low/hard state throughout the month-long outburst, although it became marginally softer at peak flux. We detected Type-C quasi-periodic oscillations (QPOs) and followed the evolution of their properties. The QPO frequency increased from ∼0.1 to ∼0.4 Hz during the rising phase of the outburst and decreased again in the decline. Continuum X-ray flux, power-law photon index, QPO frequency, and QPO root-mean-square amplitude were positively correlated. The QPO amplitude was slightly higher in the soft X-ray band (typical values of 12–16 per cent, compared with 8–10 per cent in the hard band). Our spectral-timing results shed light on the initial rising phase in the low/hard state, which has rarely been monitored with such high cadence, time resolution, and broad-band coverage. Combining spectral and timing properties, we find that ‘failed’ (hard state only) and ‘successful’ outbursts follow the same initial evolutionary track, although the former class of outburst never reaches the threshold for a transition to softer (thermally dominated) accretion regimes.

High time resolution and accuracy are of critical importance in the studies of timing analysis and time delay localization of gamma-ray bursts (GRBs), soft gamma-ray repeaters (SGRs) and pulsars. The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor (GECAM) consisting of two micro-satellites, GECAM-A and GECAM-B, launched on 2020 December 10, is aimed at monitoring and locating X-ray and GRBs all over the sky. To achieve its scientific goals, GECAM is designed to have the highest time resolution (0.1 $\mu {\rm s}$) among all GRB detectors ever flown. Here, we make a comprehensive time calibration campaign including both on-ground and on-orbit tests to derive not only the relative time accuracy of GECAM satellites and detectors, but also the absolute time accuracy of GECAM-B. Using the on-ground calibration with a $\rm ^{22}Na$ radioactive source, we find that the relative time accuracy between GECAM-A and GECAM-B is about 0.15 $\mu {\rm s}$ (1σ). To measure the relative time accuracy between all detectors of a single GECAM satellite, cosmic-ray events detected on orbit are utilized since they could produce many secondary particles simultaneously record by multiple detectors. We find that the relative time accuracy among all detectors onboard GECAM-B is about 0.12 $\mu {\rm s}$ (1σ). Finally, we use the novel Li-CCF method to perform the absolute time calibration with Crab pulsar and SGR J1935+2154, both of which were jointly observed by GECAM-B and Fermi/GBM, and obtain that the time difference between GECAM-B and Fermi/GBM is 3.06 ± 6.04 $\mu {\rm s}$ (1σ).

We report on the Insight-HXMT observations of the new black hole X-ray binary MAXI J1820+070 during its 2018 outburst. Detailed spectral analysis via the continuum fitting method shows an evolution of the inferred spin during its high soft sate. Moreover, the hardness ratio, the non-thermal luminosity and the reflection fraction also undergo an evolution, exactly coincident to the period when the inferred spin transition takes place. The unphysical evolution of the spin is attributed to the evolution of the inner disc, which is caused by the collapse of a hot corona due to condensation mechanism or may be related to the deceleration of a jet-like corona. The studies of the inner disc radius and the relation between the disc luminosity and the inner disc radius suggest that, only at a particular epoch, did the inner edge of the disc reach the innermost stable circular orbit and the spin measurement is reliable. We then constrain the spin of MAXI J1820+070 to be a*=0.2^{+0.2}_{-0.3}. Such a slowly spinning black hole possessing a strong jet suggests that its jet activity is driven mainly by the accretion disc rather than by the black hole spin., Comment: 14 pages, 13 figures, 5 tables, accepted for publication in MNRAS

Fast radio bursts (FRBs) are short pulses observed in radio band from cosmological distances. One class of models invoke soft gamma-ray repeaters (SGRs), or magnetars, as the sources of FRBs. Some radio pulses have been observed from some magnetars, however, no FRB-like events had been detected in association any magnetar burst, including one giant flare. Recently, a pair of FRB-like bursts (FRB 200428 hereafter) separated by milliseconds (ms) were detected from the general direction of the Galactic magnetar SGR J1935+2154. Here we report the detection of a non-thermal X-ray burst in the 1-250 keV energy band with the Insight-HXMT satellite, which we identify as emitted from SGR J1935+2154. The burst showed two hard peaks with a separation of 34 ms, broadly consistent with that of the two bursts in FRB 200428. The delay time between the double radio and X-ray peaks is about 8.57 s, fully consistent with the dispersion delay of FRB 200428. We thus identify the non-thermal X-ray burst is associated with FRB 200428 whose high energy counterpart is the two hard peaks in X-ray. Our results suggest that the non-thermal X-ray burst and FRB 200428 share the same physical origin in an explosive event from SGR J1935+2154., 24 pages, 9 figures, 6 tables; initial submission to a journal on May 9th, 2020. Significant changes include updated localization and detailed spectral evolution of the X-ray burst, and better determination of the two narrow X-ray peaks corresponding to the two radio pulses. Conclusions are strengthened. Nature Astronomy online on Feb. 18, 2021

We present a spectral study of the black hole candidate MAXI J1348-630 during its 2019 outburst, based on monitoring observations with Insight-HXMT and Swift. Throughout the outburst, the spectra are well fitted with power-law plus disk-blackbody components. In the soft-intermediate and soft states, we observed the canonical relation L ~ T_in^4 between disk luminosity L and peak colour temperature T_in, with a constant inner radius R_in (traditionally identified with the innermost stable circular orbit). At other stages of the outburst cycle, the behaviour is more unusual, inconsistent with the canonical outburst evolution of black hole transients. In particular, during the hard rise, the apparent inner radius is smaller than in the soft state (and increasing), and the peak colour temperature is higher (and decreasing). This anomalous behaviour is found even when we model the spectra with self-consistent Comptonization models, which take into account the up-scattering of photons from the disk component into the power-law component. To explain both those anomalous trends at the same time, we suggest that the hardening factor for the inner disk emission was larger than the canonical value of ~1.7 at the beginning of the outburst. A more physical trend of radii and temperature evolution requires a hardening factor evolving from ~3.5 at the beginning of the hard state to ~1.7 in the hard intermediate state. This could be evidence that the inner disk was in the process of condensing from the hot, optically thin medium and had not yet reached a sufficiently high optical depth for its emission spectrum to be described by the standard optically-thick disk solution., 20 pages, 10 figures, 4 tables, accepted by ApJ

Recently, the system parameters of Cygnus X-1, i.e., the black hole mass M, the orbital inclination i and the source distance D, have been updated. As the input constraints of the continuum-fitting method, it is necessary to refine the spin with these new parameters. The Hard X-ray Modulation Telescope (HXMT, also named Insight) was successfully launched on June 15th, 2017 in China. In this work, we analyzed spectra obtained by the Insight-HXMT during 2017-2018 and re-estimated the spin via the continuum-fitting method. We first re-estimated the spin using old parameters and found the dimensionless spin parameter to be a ⁎ > 0.934 (3σ), which is consistent with previous measurements both from the continuum-fitting and iron-line fitting methods ( Gou et al. 2011 , Gou et al. 2014 ; Fabian et al. 2012 , Walton et al. 2016 , Tomsick et al. 2018 ). Then, when the new parameters were applied, we obtained an increased spin: a ⁎ > 0.967 (3σ), which is also consistent with the recent measurement (Zhao et al. 2020, submitted to ApJ) and also confirms an extreme Kerr black hole lying in this system.

We present a detailed timing study of the brightest persistent X-ray source Sco X-1 using the data collected by the Hard X-ray Modulation Telescope ( I n s i g h t -HXMT) from July 2017 to August 2018. A complete Z-track hardness-intensity diagram (HID) is obtained. The normal branch oscillations (NBOs) at ∼ 6 Hz in the lower part of the normal branch (NB) and the flare branch oscillations (FBOs) at ∼ 16 Hz in the beginning part of the flaring branch (FB) are found in observations with the Low Energy X-ray Telescope (LE) and the Medium Energy X-ray Telescope (ME) of I n s i g h t -HXMT, while the horizontal branch oscillations (HBOs) at ∼ 40 Hz and the kilohertz quasi-periodic oscillations (kHz QPOs) at ∼ 800 Hz are found simultaneously above 20 keV for the first time on the horizontal branch (HB) by the High Energy X-ray Telescope (HE) and ME. We find that for all types of the observed QPOs, the centroid frequencies are independent of energy, while the root mean square (rms) increases with energy; the centroid frequencies of both the HBOs and kHz QPOs increase along the Z-track from the top to the bottom of the HB; and the NBOs show soft phase lags increasing with energy. A continuous QPO transition from the FB to NB in ∼ 200 s are also detected. Our results indicate that the non-thermal emission is the origin of all types of QPOs, the innermost region of the accretion disk is non-thermal in nature, and the corona is nonhomogeneous geometrically.

The evidences for the influence of thermonuclear (type-I) X-ray bursts upon the surrounding environments in neutron star low-mass X-ray binaries (LMXB) were detected previously via spectral and timing analyses. Benefitting from a broad energy coverage of Insight-HXMT, we analyze one photospheric radius expansion (PRE) burst, and find an emission excess at soft X-rays. Our spectral analysis shows that, such an excess is not likely relevant to the disk reflection induced by the burst emission and can be attributed to an enhanced pre-burst/persistent emission. We find that the burst and enhanced persistent emissions sum up to exceed Eddington luminosity by ∼ 40 percentages. We speculate that the enhanced emission is from a region beyond the PRE radius, or through the Comptonization of the corona.

The High Energy X-ray telescope (HE) on-board the Hard X-ray Modulation Telescope (\textit{Insight}-HXMT) can serve as a wide Field of View (FOV) gamma-ray monitor with high time resolution ($\mu$s) and large effective area (up to thousands cm$^2$). We developed a pipeline to search for Gamma-Ray Bursts (GRBs), using the traditional signal-to-noise ratio (SNR) method for blind search and the coherent search method for targeted search. By taking into account the location and spectrum of the burst and the detector response, the targeted coherent search is more powerful to unveil weak and sub-threshold bursts, especially those in temporal coincidence with Gravitational Wave (GW) events. Based on the original method in literature, we further improved the coherent search to filter out false triggers caused by spikes in light curves, which are commonly seen in gamma-ray instruments (e.g. \textit{Fermi}/GBM, \textit{POLAR}). We show that our improved targeted coherent search method could eliminate almost all false triggers caused by spikes. Based on the first two years of \textit{Insight}-HXMT/HE data, our targeted search recovered 40 GRBs, which were detected by either \textit{Swift}/BAT or \textit{Fermi}/GBM but too weak to be found in our blind search. With this coherent search pipeline, the GRB detection sensitivity of \textit{Insight}-HXMT/HE is increased to about 1.5E-08 erg/cm$^2$ (200 keV$-$3 MeV). We also used this targeted coherent method to search \textit{Insight}-HXMT/HE data for electromagnetic (EM) counterparts of LIGO-Virgo GW events (including O2 and O3a runs). However, we did not find any significant burst associated with GW events., Comment: 12 pages, 14 figures, 5 tables; accepted for publication in MNRAS

We report the energy-resolved broadband timing analysis of the black hole X-ray transient MAXI J1631-479 during its 2019 outburst from February 11 to April 9, using data from the Insight-Hard X-ray Modulation Telescope (Insight-HXMT), which caught the source from its hard intermediate state to the soft state. Thanks to the large effective area of Insight-HXMT at high energies, we are able to present the energy dependence of fast variability up to ~100 keV. Type-C quasi-periodic oscillations (QPOs) with frequency varying between 4.9 Hz and 6.5 Hz are observed in the 1-100 keV energy band. While the QPO fractional rms increases with photon energy from 1 keV to ~10 keV and remains more or less constant from ~10 keV to ~100 keV, the rms of the flat-top noise first increases from 1 keV to ~8 keV then drops to less than 0.1% above ~30 keV. We suggest that the disappearance of the broadband variability above 30 keV could be caused by the non-thermal acceleration in the Comptonizing plasma. At the same time, the QPOs could be produced by the precession of either a small-scale jet or a hot inner flow model., To be published in The Astrophysical Journal

In this paper, we presented a detailed timing analysis of a prominent outburst of 4U 0115+63 detected by \textit{Insight}-HXMT in 2017 August. The spin period of the neutron star was determined to be $3.61398\pm 0.00002$ s at MJD 57978. We measured the period variability and extract the orbital elements of the binary system. The angle of periastron evolved with a rate of $0.048\pm0.003$ $yr^{-1}$. The light curves are folded to sketch the pulse profiles in different energy ranges. A multi-peak structure in 1-10 keV is clearly illustrated. We introduced wavelet analysis into our data analysis procedures to study QPO signals and perform a detailed wavelet analysis in many different energy ranges. Through the wavelet spectra, we report the discovery of a QPO at the frequency $\sim 10$ mHz. In addition, the X-ray light curves showed multiple QPOs in the period of $\sim 16-32 $ s and $\sim 67- 200 $ s. We found that the $\sim100$ s QPO was significant in most of the observations and energies. There exist positive relations between X-ray luminosity and their Q-factors and S-factors, while the QPO periods have no correlation with X-ray luminosity. In wavelet phase maps, we found that the pulse phase of $\sim 67- 200 $ s QPO drifting frequently while the $\sim 16-32 $ s QPO scarcely drifting. The dissipation of oscillations from high energy to low energy was also observed. These features of QPOs in 4U 0115+63 provide new challenge to our understanding of their physical origins., 14 pages, 9 figures, and 6 tables. This work has been submitted to MNRAS after the referee's report

The Gravitational Wave highly energetic Electromagnetic Counterpart All-sky Monitor (GECAM) is dedicated to detecting gravitational wave gamma-ray bursts. It is capable of all-sky monitoring over and discovering gamma-ray bursts and new radiation phenomena. GECAM consists of two microsatellites, each equipped with 8 charged particle detectors (CPDs) and 25 gamma-ray detectors (GRDs). The CPD is used to measure charged particles in the space environment, monitor energy and flow intensity changes, and identify between gamma-ray bursts and space charged particle events in conjunction with GRD. CPD uses plastic scintillator as the sensitive material for detection, silicon photomultiplier (SiPM) array as the optically readable device, and the inlaid Am-241 radioactive source as the onboard calibration means. In this paper, we will present the working principle, physical design, functional implementation and preliminary performance test results of the CPD., Comment: accepted to RDTM

Background: Each GECAM satellite payload contains 25 gamma-ray detectors (GRDs), which can detect gamma-rays and particles and can roughly localize the Gamma-Ray Bursts (GRBs). GRD was designed using lanthanum bromide (LaBr3) crystal as the sensitive material with the rear end coupled with silicon photomultiplier (SiPM) array for readout. Purpose: In aerospace engineering design of GRD, there are many key points to be studied. In this paper, we present the specific design scheme of GRD, the assembly and the performance test results of detectors. Methods: Based on Monte Carlo simulation and experimental test results, the specific schematic design and assembling process ofGRDwere optimized. After being fully assembled, theGRDswere conducted performance tests by using radioactive source and also conducted random vibration tests. Result and conclusion: The test results show that all satellite-borne GRDs have energy resolution, 10 pages, 15 figures

Based on Insight-HXMT data, we report on the pulse fraction evolution during the 2017–2018 outburst of the newly discovered first Galactic ultraluminous X-ray (ULX) source Swift J0243.6+6124. The pulse fractions of 19 observation pairs selected in the rising and fading phases with similar luminosity are investigated. The results show a general trend of the pulse fraction increasing with luminosity and energy at supercritical luminosity. However, the relative strength of the pulsation between each pair evolves strongly with luminosity. The pulse fraction in the rising phase is larger at luminosity below 7.71 × 1038 erg s−1, but smaller at above. A transition luminosity is found to be energy independent. Such a phenomenon is first confirmed by Insight-HXMT observations and we speculate that it may have relation with the radiation-pressure-dominated accretion disc.

We study the evolution of the temporal properties of MAXI 1820+070 during the 2018 outburst in its hard state from MJD 58190 to 58289 with Insight-HXMT in a broad energy band 1-150 keV. We find different behaviors of the hardness ratio, the fractional rms and time lag before and after MJD 58257, suggesting a transition occurred at around this point. The observed time lags between the soft photons in the 1-5 keV band and the hard photons in higher energy bands, up to 150 keV, are frequency-dependent: the time lags in the low-frequency range, 2-10 mHz, are both soft and hard lags with a timescale of dozens of seconds but without a clear trend along the outburst; the time lags in the high-frequency range, 1-10 Hz, are only hard lags with a timescale of tens of milliseconds; first increase until around MJD 58257 and decrease after this date. The high-frequency time lags are significantly correlated to the photon index derived from the fit to the quasi-simultaneous NICER spectrum in the 1-10 keV band. This result is qualitatively consistent with a model in which the high-frequency time lags are produced by Comptonization in a jet., Comment: Accepted for publication in ApJ

We report on our analysis of the 2019 outburst of the X-ray accreting pulsar 4U 1901+03 observed with Insight-HXMT and NICER. Both spectra and pulse profiles evolve significantly in the decaying phase of the outburst. Dozens of flares are observed throughout the outburst. They are more frequent and brighter at the outburst peak. We find that the flares, which have a duration from tens to hundreds of seconds, are generally brighter than the persistent emission by a factor of $\sim$ 1.5. The pulse profile shape during the flares can be significantly different than that of the persistent emission. In particular, a phase shift is clearly observed in many cases. We interpret these findings as direct evidence of changes of the pulsed beam pattern, due to transitions between the sub- and super-critical accretion regimes on a short time scale. We also observe that at comparable luminosities the flares' pulse profiles are rather similar to those of the persistent emission. This indicates that the accretion on the polar cap of the neutron star is mainly determined by the luminosity, i.e., the mass accretion rate., 11 pages, 8 figures, accepted for publication in MNRAS

No robust detection of prompt electromagnetic counterparts to fast radio bursts (FRBs) has yet been obtained, in spite of several multi-wavelength searches carried out so far. Specifically, X/gamma-ray counterparts are predicted by some models. We planned on searching for prompt gamma-ray counterparts in the Insight-Hard X-ray Modulation Telescope (Insight-HXMT) data, taking advantage of the unique combination of large effective area in the keV-MeV energy range and of sub-ms time resolution. We selected 39 FRBs that were promptly visible from the High-Energy (HE) instrument aboard Insight-HXMT. After calculating the expected arrival times at the location of the spacecraft, we searched for a significant excess in both individual and cumulative time profiles over a wide range of time resolutions, from several seconds down to sub-ms scales. Using the dispersion measures in excess of the Galactic terms, we estimated the upper limits on the redshifts. No convincing signal was found and for each FRB we constrained the gamma-ray isotropic-equivalent luminosity and the released energy as a function of emission timescale. For the nearest FRB source, the periodic repeater FRB180916.J0158+65, we find $L_{\gamma,iso}, Comment: 15 pages, 3 figures, 6 tables, accepted by A&A

We report on the observation of the accreting pulsar GRO J1008-57 performed by Insight-HXMT at the peak of the source's 2017 outburst. Pulsations are detected with a spin period of 93.283(1) s. The pulse profile shows double peaks at soft X-rays, and only one peak above 20 keV. The spectrum is well described by the phenomenological models of X-ray pulsars. A cyclotron resonant scattering feature is detected with very high statistical significance at a centroid energy of $E_{\rm cyc}=90.32_{-0.28}^{+0.32}$ keV, for the reference continuum and line models, HIGHECUT and GABS respectively. Detection is very robust with respect to different continuum models. The line energy is significantly higher than what suggested from previous observations, which provided very marginal evidence for the line. This establishes a new record for the centroid energy of a fundamental cyclotron resonant scattering feature observed in accreting pulsars. We also discuss the accretion regime of the source during the Insight-HXMT observation., Comment: 8 pages, 3 figures, accepted for publication in ApJL

A link between magnetars and fast radio burst (FRB) sources has finally been established. In this context, one of the open issues is whether/which sources of extra galactic FRBs exhibit X/gamma-ray outbursts and whether it is correlated with radio activity. We aim to constrain possible X/gamma-ray burst activity from one of the nearest extragalactic FRB sources currently known over a broad energy range, by looking for bursts over a range of timescales and energies that are compatible with being powerful flares from extragalactic magnetars. We followed up the as-yet nearest extragalactic FRB source at a mere 149 Mpc distance, the periodic repeater FRB180916.J0158+65, during the active phase on February 4-7, 2020, with the Insight-Hard X-ray Modulation Telescope (HXMT). Taking advantage of the combination of broad band, large effective area, and several independent detectors available, we searched for bursts over a set of timescales from 1 ms to 1.024 s with a sensitive algorithm, that had previously been characterised and optimised. Moreover, through simulations we studied the sensitivity of our technique in the released energy-duration phase space for a set of synthetic flares and assuming different energy spectra. We constrain the possible occurrence of flares in the 1-100 keV energy band to E, 10 pages, 3 figures, accepted by A&A

We investigate the absorption and emission features in observations of GX 301-2 detected with Insight-HXMT/LE in 2017-2019. At different orbital phases, we found prominent Fe Kalpha, Kbeta and Ni Kalpha lines, as well as Compton shoulders and Fe K-shell absorption edges. These features are due to the X-ray reprocessing caused by the interaction between the radiation from the source and surrounding accretion material. According to the ratio of iron lines Kalpha and Kbeta, we infer the accretion material is in a low ionisation state. We find an orbital-dependent local absorption column density, which has a large value and strong variability around the periastron. We explain its variability as a result of inhomogeneities of the accretion environment and/or instabilities of accretion processes. In addition, the variable local column density is correlated with the equivalent width of the iron Kalpha lines throughout the orbit, which suggests that the accretion material near the neutron star is spherically distributed., Comment: 10 pages, 5 figures, 2 tables, accepted for publication in MNRAS

Glitches correspond to sudden jumps of rotation frequency ($\nu$) and its derivative ($\dot{\nu}$) of pulsars, the origin of which remains not well understood yet, partly because the jump processes of most glitches are not well time-resolved. There are three large glitches of the Crab pulsar, detected in 1989, 1996 and 2017, which were found to have delayed spin-up processes before the normal recovery processes. Here we report two additional glitches of the Crab pulsar occurred in 2004 and 2011 for which we discovered delayed spin up processes, and present refined parameters of the largest glitch occurred in 2017. The initial rising time of the glitch is determined as $, Comment: 25 pages, 8 figures

We report on analysis of observations of the bright transient X-ray pulsar \src obtained during its 2017-2018 giant outburst with Insight-HXMT, \emph{NuSTAR}, and \textit{Swift} observatories. We focus on the discovery of a sharp state transition of the timing and spectral properties of the source at super-Eddington accretion rates, which we associate with the transition of the accretion disk to a radiation pressure dominated (RPD) state, the first ever directly observed for magnetized neutron star. This transition occurs at slightly higher luminosity compared to already reported transition of the source from sub- to super-critical accretion regime associate with onset of an accretion column. We argue that this scenario can only be realized for comparatively weakly magnetized neutron star, not dissimilar to other ultra-luminous X-ray pulsars (ULPs), which accrete at similar rates. Further evidence for this conclusion is provided by the non-detection of the transition to the propeller state in quiescence which strongly implies compact magnetosphere and thus rules out magnetar-like fields., Submitted to MNRAS

We present a study of timing properties of the accreting pulsar 2S 1417-624 observed during its 2018 outburst, based on Swift/BAT, Fermi/GBM, Insight-HXMT and NICER observations. We report a dramatic change of the pulse profiles with luminosity. The morphology of the profile in the range 0.2-10.0keV switches from double to triple peaks at $\sim2.5$ $\rm \times 10^{37}{\it D}_{10}^2\ erg\ s^{-1}$ and from triple to quadruple peaks at $\sim7$ $\rm \times 10^{37}{\it D}_{10}^2\ erg\ s^{-1}$. The profile at high energies (25-100keV) shows significant evolutions as well. We explain this phenomenon according to existing theoretical models. We argue that the first change is related to the transition from the sub to the super-critical accretion regime, while the second to the transition of the accretion disc from the gas-dominated to the radiation pressure-dominated state. Considering the spin-up as well due to the accretion torque, this interpretation allows to estimate the magnetic field self-consistently at $\sim7\times 10^{12}$G., 7 pages, 4 figures, 1 tables, accepted for publication in MNRAS

Objectives The aim of this study was to identify the status of the blood supply in China during 2012-2014. Background China is a middle-income country, which contains more than 20% of the world population. Increasing the blood supply in China, along with increased healthcare coverage, involves many challenges. Methods A survey questionnaire regarding blood centre activities was sent to all of the blood centres in 32 provinces via the Internet. The data were collected from the responses and analysed using Microsoft Excel 2013. Results The total supply of whole blood and red blood cells (RBCs) in 2012 was 18 644 700 units; in 2013, 18 985 800 units; and in 2014, 19 658 800 units. A similar trend of the total platelet supply was also observed during the same period of 2012-2014, as follows: 1 019 100 units in 2012, 1 168 400 units in 2013 and 1 276 200 units in 2014. Similarly, the plasma supply was 27 529 300 units in 2012 and 27 657 600 units in 2013, which rose to 28 307 500 units in 2014. The total cryoprecipitate supply was 1 653 900, 1 891 300 and 2 366 500 units in 2012, 2013 and 2014, respectively. When the blood supply was analysed according to the geographic regional population, large differences in the rates of blood supply between regions were evident. Conclusions The blood product supply in China is steadily increasing. Blood centres in China continue to face challenges regarding their ability to provide a sufficient blood supply in the future.

The China Seismo-Electromagnetic Satellite (CSES) aims to monitor space electromagnetic fields, ionospheric plasma, high-energy charged particles and other features of the global space environment. The high-energy particle package (HEPP), which can effectively detect the energy spectrum, flux and pitch angle distribution of space electrons and protons, and soft X-ray emission from solar flares, is one of the main payloads of CSES. In this study, we designed, developed and calibrated the high-energy particle package and launched it into orbit with CSES. HEPP consists of the high-energy detector (HEPP-H), the low-energy detector (HEPP-L), and the solar X-ray monitor (HEPP-X). The three sub-detectors mainly use silicon detector and crystal calorimeter detection technology. Before launching, we calibrated the three sub-detectors in detail by using radiation source and accelerator beam. All the three sub-detectors have good energy linearity. After launching into orbit, the space energetic particles and X-ray distribution detected by HEPP are consistent with expectations. The performance indices of the detector reach the advanced level of the same kind of detector in the world. HEPP has a wide energy detection range, good energy resolution and high angular resolution ability for electrons and protons. It will play an important role in the study of space particle response and space physics of seismic activity.

The recently discovered neutron star transient Swift J0243.6+6124 has been monitored by {\it the Hard X-ray Modulation Telescope} ({\it Insight-\rm HXMT). Based on the obtained data, we investigate the broadband spectrum of the source throughout the outburst. We estimate the broadband flux of the source and search for possible cyclotron line in the broadband spectrum. No evidence of line-like features is, however, found up to $\rm 150~keV$. In the absence of any cyclotron line in its energy spectrum, we estimate the magnetic field of the source based on the observed spin evolution of the neutron star by applying two accretion torque models. In both cases, we get consistent results with $B\rm \sim 10^{13}~G$, $D\rm \sim 6~kpc$ and peak luminosity of $\rm >10^{39}~erg~s^{-1}$ which makes the source the first Galactic ultraluminous X-ray source hosting a neutron star., published

We present the analysis of the brightest flare that was recorded in the \emph{Insight}-HMXT data set, in a broad energy range (2$-$200 keV) from the microquasar GRS~1915+105 during an unusual low-luminosity state. This flare was detected by \emph{Insight}-HXMT among a series of flares during 2 June 2019 UTC 16:37:06 to 20:11:36, with a 2-200 keV luminosity of 3.4$-$7.27$\times10^{38}$ erg s$^{-1}$. Basing on the broad-band spectral analysis, we find that the flare spectrum shows different behaviors during bright and faint epochs. The spectrum of the flare can be fitted with a model dominated by a power-law component. Additional components show up in the bright epoch with a hard tail and in the faint epoch with an absorption line $\sim$ 6.78 keV. The reflection component of the latter is consistent with an inner disk radius $\sim$ 5 times larger than that of the former. These results on the giant flare during the "unusual" low-luminosity state of GRS~1915+105 may suggest that the source experiences a possible fast transition from a jet-dominated state to a wind-dominated state. We speculate that the evolving accretion disk and the large-scale magnetic field may play important roles in this peculiar huge flare.

We present the X-ray timing results of the new black hole candidate (BHC) MAXI J1535-571 during its 2017 outburst from Hard X-ray Modulation Telescope (\emph{Insight}-HXMT) observations taken from 2017 September 6 to 23. Following the definitions given by \citet{Belloni2010}, we find that the source exhibits state transitions from Low/Hard state (LHS) to Hard Intermediate state (HIMS) and eventually to Soft Intermediate state (SIMS). Quasi-periodic oscillations (QPOs) are found in the intermediate states, which suggest different types of QPOs. With the large effective area of \emph{Insight}-HXMT at high energies, we are able to present the energy dependence of the QPO amplitude and centroid frequency up to 100 keV which is rarely explored by previous satellites. We also find that the phase lag at the type-C QPOs centroid frequency is negative (soft lags) and strongly correlated with the centroid frequency. By assuming a geometrical origin of type-C QPOs, the source is consistent with being a high inclination system., Comment: 12 pages, 11 figures, Sumbitted to ApJ

The aim of this study was to identify the status of the blood supply in China during 2012-2014.China is a middle-income country, which contains more than 20% of the world population. Increasing the blood supply in China, along with increased healthcare coverage, involves many challenges.A survey questionnaire regarding blood centre activities was sent to all of the blood centres in 32 provinces via the Internet. The data were collected from the responses and analysed using Microsoft Excel 2013.The total supply of whole blood and red blood cells (RBCs) in 2012 was 18 644 700 units; in 2013, 18 985 800 units; and in 2014, 19 658 800 units. A similar trend of the total platelet supply was also observed during the same period of 2012-2014, as follows: 1 019 100 units in 2012, 1 168 400 units in 2013 and 1 276 200 units in 2014. Similarly, the plasma supply was 27 529 300 units in 2012 and 27 657 600 units in 2013, which rose to 28 307 500 units in 2014. The total cryoprecipitate supply was 1 653 900, 1 891 300 and 2 366 500 units in 2012, 2013 and 2014, respectively. When the blood supply was analysed according to the geographic regional population, large differences in the rates of blood supply between regions were evident.The blood product supply in China is steadily increasing. Blood centres in China continue to face challenges regarding their ability to provide a sufficient blood supply in the future.

Finding the electromagnetic (EM) counterpart of binary compact star merger, especially the binary neutron star (BNS) merger, is critically important for gravitational wave (GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017, Advanced LIGO and \textit{Fermi}/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart, GRB 170817A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope (HE) onboard \textit{Insight}-HXMT (Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart (SSS17a/AT2017gfo) with very large collection area ($\sim$1000 cm$^2$) and microsecond time resolution in 0.2-5 MeV. In addition, \textit{Insight}-HXMT quickly implemented a Target of Opportunity (ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although it did not detect any significant high energy (0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817A. Meanwhile, \textit{Insight}-HXMT/HE provides one of the most stringent constraints (~10$^{-7}$ to 10$^{-6}$ erg/cm$^2$/s) for both GRB170817A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of \textit{Insight}-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event., Comment: accepted by Science China - Physics, Mechanics & Astronomy. Planned to publish on Oct 17, but postponed due to a problem on pdf file

In this work, we report the in-orbit demonstration of X-ray pulsar navigation with Insight-Hard X-ray Modulation Telescope (Insight-HXMT), which was launched on Jun. 15th, 2017. The new pulsar navigation method 'Significance Enhancement of Pulse-profile with Orbit-dynamics' (SEPO) is adopted to determine the orbit with observations of only one pulsar. In this test, the Crab pulsar is chosen and observed by Insight-HXMT from Aug. 31th to Sept. 5th in 2017. Using the 5-day-long observation data, the orbit of Insight-HXMT is determined successfully with the three telescopes onboard - High Energy X-ray Telescope (HE), Medium Energy X-ray Telescope (ME) and Low Energy X-ray Telescope (LE) - respectively. Combining all the data, the position and velocity of the Insight-HXMT are pinpointed to within 10 km (3 sigma) and 10 m/s (3 sigma), respectively., Accepted by the Astrophysical Journal Supplement

To detect the changes of （interleukin, IL） -1α, IL-1β and IL-13 mRNA in lung tissue and serum of drown rats, and to explore the potential value for the diagnosis of drowning in forensic practice.Eighteen SD rats were randomly divided into drowning group, blank control group and myocardial infarction group （as control group）. The serum of right ventricular, the inferior lobe of right lung and the myocardium were taken from the rats in different groups. The expressions of IL-1α, IL-1β and IL-13 mRNA in the lung tissue and the serum of right ventricular were detected by TaqMan probe method.The expression differences of IL-1α, IL-1β and IL-13 mRNA in lung tissue between drowning group and blank control group, myocardial infarction group were not statistically significant （The changes of cytokines IL-1β and IL-13 mRNA in the serum of right ventricular of drown rats are statistical significance, which are highly correlated with drowning.

Adsorption of carrier-free radiotracers 181W and 93mMo produced in the 181Ta(p, n) and natNb(p, n) reactions, respectively, on anion-exchange resin was studied in mixed solution of HF and HNO3 in a concentration range of 10−4–10−1 M HF/0.1 M HNO3. Distribution coefficients (Kd) of 181W and 93mMo at 70 °C showed the V-shaped variation with the minimum at around 10−1 M HF/0.1 M HNO3, although variation of the Kd values for 93mMo was quite small compared with that for 181W. Formation of oxofluoro complexes for W and Mo is briefly discussed.

The cation-exchange behavior of261Rf (T1/2= 78 s) produced in the248Cm(18O, 5n) reaction was studied on a “one-atom-at-a-time” scale in 0.15–0.69 M H2SO4/HNO3mixed solutions ([H+]=1.0 M) using an automated ion-exchange separation apparatus coupled with the detection system for alpha-spectroscopy (AIDA). It was found that adsorption probabilities ( decrease with an increase of [HSO4−], showing a successive formation of Rf sulfate complexes. Rf exhibits a weaker complex formation tendency compared to the lighter homologues Zr and Hf. This is in good agreement with theoretical predictions including relativistic effects.

Summary Introduction: Genotyping of human platelet antigens (HPA) is useful for the diagnosis and prevention of platelet alloimmune syndromes. HPA-15 might play an important role in the development of platelet alloimmune syndromes. There are several disadvantages in the conventional methods for HPA-15 genotyping. The aim of this study was to develop a new method for HPA-15 genotyping by using single closed-tube melting temperature (Tm)-shift genotyping. Methods: Two GC-rich tails of different lengths were attached to 5′-end of HPA-15 allele-specific PCR primers, such that HPA-15 alleles can be discriminated by the Tms of the PCR products. One hundred blood samples were genotyped for HPA-15 by the Tm-shift and conventional polymerase chain reaction with sequence-specific primers (PCR-SSP). Results: The comparison of the PCR-SSP and the Tm-shift method showed four discordant results in one hundred samples tested. Confirmatory results demonstrated that the PCR-SSP produced several errors, whereas HPA-15 genotyping by Tm-shift is correct. The retesting results of Tm-shift method were consistent with those of the initial testing. Conclusion: The single closed-tube Tm-shift method for HPA-15 genotyping is high-throughput, rapid, reliable, reproducible and cost-effective and it is superior to conventional PCR-SSP used in routine genotyping of HPA-15.

Corona cooling was detected previously from stacking a series of short type-I bursts occurred during the low/had state of atoll outburst. Type-I bursts are hence regarded as sharp probe to our better understanding on the basic property of the corona. The launch of the first Chinese X-ray satellite Insight-HXMT has large detection area at hard X-rays which provide almost unique chance to move further in this research field. We report the first detection of the corona cooling by Insight-HXMT from single short type-I burst showing up during {\bf flare} of 4U 1636-536. This type-I X-ray burst has a duration of $\sim$13 seconds and hard X-ray shortage is detected with significance 6.2~$\sigma$ in 40-70 keV. A cross-correlation analysis between the lightcurves of soft and hard X-ray band, shows that the corona shortage lag the burst emission by 1.6 $\pm$1.2~s. These results are consistent with those derived previously from stacking a large amount of bursts detected by RXTE/PCA within a series of {\bf flares} of 4U 1636-536. Moreover, the broad bandwidth of Insight-HXMT allows as well for the first time to infer the burst influence upon the continuum spectrum via performing the spectral fitting of the burst, which ends up with the finding that hard X-ray shortage appears at around 40 keV in the continuum spectrum. These results suggest that the evolution of the corona along with the outburst{\bf /flare} of NS XRB may be traced via looking into a series of embedded type-I bursts by using Insight-HXMT., Comment: published in 2018, ApJL,864, L30

The NiCoCrAlYTa coating was prepared on Ni -based single crystal super-alloys by low pressure plasma spraying (LPPS). The phases and microstructures for the coatings were characterized by X-ray diffraction and scanning electron microscopy, and the fracture toughness and micro-hardness for both coatings and substrate were also investigated. The relationship between coating properties and oxidation was analyzed. The result shows that elementary distribution of NiCoCrAlYTa coatings, which consists of γ- Ni , β- NiAl , γ'- Ni 3 Al , and CrCoTa phases, is much homogeneous. The composition changes with depth from the surface to substrate for the coatings. The micro-hardness of coatings is 350.8 HV0.3 and fracture toughness is 2.73 MPa m1/2. The oxidation resistance of coatings excelled than Ni -based single crystal super-alloys.

The NiCoCrAlYTa coating was prepared on Ni-based single crystal super-alloys by low pressure plasma spraying (LPPS). The phases and microstructures for the coatings were characterized by X-ray diffraction and scanning electron microscopy, and the fracture toughness and micro-hardness for both coatings and substrate were also investigated. The relationship between coating properties and oxidation was analyzed. The result shows that elementary distribution of NiCoCrAlYTa coatings, which consists of γ-Ni, β-NiAl, γ'-Ni3Al, and CrCoTa phases, is much homogeneous. The composition changes with depth from the surface to substrate for the coatings. The micro-hardness of coatings is 350.8 HV0.3 and fracture toughness is 2.73 MPa m1/2. The oxidation resistance of coatings excelled than Ni-based single crystal super-alloys.

We investigated the relationships between paraoxonase genetic polymorphisms and essential hypertension in carotid artery atherosclerotic patients. The study included 353 Han participants and 240 Uighur participants from Xinjiang; they were further divided into two groups: essential hypertension with carotid artery atherosclerosis (CAAD group) and essential hypertension without carotid artery atherosclerosis (control group). Genotypes were detected by PCR, followed by restriction analyses with specific endonucleases. In Han people, the M allele frequency was significantly higher in the CAAD group than in the control group. The CC/CS genotype and C allele frequencies were significantly higher in the CAAD group than in the control group. Logistic regression analysis demonstrated that PON1 55M allele [odds ratio (OR) = 1.889] and PON2 311C allele (OR = 1.692) are independent risk factors for CAAD. Combined genotype analysis showed that PON1 55M and PON2 311C alleles are independent risk factors for CAAD (OR = 1.428). In the Uighur population, the CC/ CS genotype and C allele frequencies were significantly higher in the CAAD group than in the control group. Logistic regression analysis demonstrated that the PON2 311C allele is an independent risk factor for CAAD. We conclude that the PON1 55M and PON2 311C alleles are independent risk factors for CAAD in essential hypertension patients from the Xinjiang Han population. We also conclude that the PON2 311C allele is a risk factor for CAAD in essential hypertension patients from the Xinjiang Uighur population.