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1. Comment je fais une formation par la simulation pour les internes du DES de radiologie ? Exemple de la prise en charge d’une alerte AVC

Author: V. Delemar, B. Casolla, F. Kryszewski, X. Leclerc, M. Jourdain, R. Azzouz, C. Cordonnier, J.-P. Pruvo, and G. Kuchcinski
Subjects: General Medicine
Published: 2023

2. Is malignant edema and hemorrhage after occlusion of high-flow arteriovenous malformation related to the size of feeding arteries and draining veins?

Author: R. Aboukais, A. Devalckeneer, P. Boussemart, P. Bourgeois, T. Menovsky, X. Leclerc, M. Vinchon, and J.-P. Lejeune
Subjects: Intracranial Arteriovenous Malformations, Microsurgery, Angiography, Digital Subtraction, Humans, Surgery, Hemorrhage, Neurology (clinical), Arteries, Human medicine
Abstract: Objective. - Our study aimed to identify predictive factors for malignant post-treatment edema and hem-orrhage in patients who underwent microsurgical treatment of arteriovenous malformation (AVM) in our institution.Methods. - The study included 72 patients treated by microsurgery for cerebral symptomatic and/or ruptured AVM between 2010 and 2020. Six patients developed postprocedural malignant edema and hemorrhage (group M); the other 66 patients had no malignant edema and hemorrhage (group NM). In each patient, flow was assessed indirectly by summing the diameters of all feeding arteries to obtain an overall diameter (ODA), and similarly for draining veins (ODV). High-flow was defined as a delay between feeding artery injection and draining vein injection (DAV) < 1 second on dynamic digital subtraction angiography. Univariate analysis was performed. Results. - Mean ODA and ODV were respectively 11 mm (+/- 8.2) and 11 mm (+/- 5.3) in group M and 2.9 mm (+/- 1.4) and 3.7 mm (+/- 1.3) in group NM (P = 0.001). High-flow AVM was demonstrated in 4 out of 5 patients (85%) in group M and in 14 out of 55 (25%) in group NM (P = 0.02). Associated aneurysm was seen in 5 patients in group M (83%) and in 11 in group NM (17%) (P = 0.001).Conclusion. - High-flow AVM may be associated with higher risk of postoperative edema and hemorrhage. Multidisciplinary discussion is mandatory in these cases, to define a pre-therapeutic plan for progressive staged vascular malformation occlusion.(c) 2022 Elsevier Masson SAS. All rights reserved.
Published: 2022

3. MRI of myelitis

Author: J Hodel, O Outteryck, P Jissendi, M Zins, X Leclerc, and J P Pruvo
Subjects: Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract: The diagnosis of myelitis relies on MRI. The purpose of this review is to describe the imaging findings in patients with myelitis through clinical cases. MR findings in Multiple Sclerosis, Neuromyelitis Optica and others Transverse Myelitis are highlighted.
Published: 2012
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4. Fistule durale intracrânienne à drainage veineux périmédullaire : un diagnostic à ne pas méconnaître en IRM

Author: Q. Vannod-Michel, L. Cotten, Martin Bretzner, Apolline Kazemi, A. Eddhif, R. Aboukais, X. Leclerc, Grégory Kuchcinski, and J.P. Pruvo
Subjects: Neurology (clinical)
Published: 2018

5. Optical coherence tomography for detection of asymptomatic optic nerve lesions in clinically isolated syndrome

Author: Renaud Lopes, Mickaël Zedet, Jean-Pierre Pruvo, Nawal Hadhoum, Elodie Drumez, Julien Labreuche, Olivier Outteryck, Hélène Zéphir, Julien Lannoy, X. Leclerc, Patrick Vermersch, and Julie Boucher
Subjects: Adult, Male, medicine.medical_specialty, Multiple Sclerosis, genetic structures, Nerve fiber layer, Visual Acuity, Asymptomatic, Retina, 030218 nuclear medicine & medical imaging, Lesion, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Medicine, Humans, Optic neuritis, Prospective Studies, Clinically isolated syndrome, business.industry, Oligoclonal Bands, Retinal, Optic Nerve, Syndrome, medicine.disease, Magnetic Resonance Imaging, eye diseases, Ganglion, medicine.anatomical_structure, Cross-Sectional Studies, chemistry, Asymptomatic Diseases, Optic nerve, Disease Progression, Female, sense organs, Neurology (clinical), Radiology, medicine.symptom, business, 030217 neurology & neurosurgery, Tomography, Optical Coherence
Abstract: ObjectiveTo evaluate the ability of intereye retinal thickness difference (IETD) measured by optical coherence tomography (OCT) to detect asymptomatic optic nerve involvement in clinically isolated syndrome (CIS).MethodsWe conducted a cross-sectional study of patients who recently presented a CIS (≤4.5 months). All patients underwent OCT and brain/optic nerve MRI. Optic nerve involvement was defined clinically (episode of optic neuritis [ON] or not) and radiologically (optic nerve hypersignal on 3D double inversion recovery [3D-DIR]). We evaluated the sensitivity and specificity of previously published IETD thresholds and report the observed optimal thresholds for identifying symptomatic optic nerve involvement but also for identifying asymptomatic optic nerve involvement (optic nerve hypersignal without ON history). Primary outcomes were ganglion cell–inner plexiform layer (GC-IPL) and peripapillary retinal nerve fiber layer IETD.ResultsThe study group consisted of 130 patients. In the CIS with ON group, 3D-DIR showed a hypersignal in all 41 symptomatic optic nerves and in 11 asymptomatic optic nerves. In the CIS without ON group, 3D-DIR showed a unilateral optic nerve hypersignal in 22 patients and a bilateral optic nerve hypersignal in 7 patients. For the detection of symptomatic and asymptomatic optic nerve lesion, GC-IPL IETD had better performance. We found an optimal GC-IPL IETD threshold ≥2.83 µm (sensitivity 88.2, specificity 83.3%) for the detection of symptomatic lesions and an optimal GC-IPL IETD ≥1.42 µm (sensitivity 89.3%, specificity 72.6%) for the detection of asymptomatic lesions.ConclusionsDetection of asymptomatic optic nerve lesions in CIS requires lower IETD thresholds than previously reported. GC-IPL IETD represents an alternative biomarker to MRI for the detection of asymptomatic optic nerve lesions.Classification of evidenceThis study provides Class I evidence that OCT accurately identifies asymptomatic optic nerve involvement in patients with CIS.
Published: 2019

6. Asymptomatic optic nerve lesions: An underestimated cause of silent retinal atrophy in MS

Author: Renaud Lopes, X. Leclerc, Elodie Drumez, Hélène Zéphir, Patrick Vermersch, Nawal Hadhoum, Olivier Outteryck, Julien Labreuche, Jean-Baptiste Davion, Jean-Pierre Pruvo, and Julien Lannoy
Subjects: 0301 basic medicine, Male, Visual acuity, genetic structures, Nerve fiber layer, Pilot Projects, 0302 clinical medicine, Nerve Fibers, Visual Cortex, Natalizumab, Retinal Degeneration, Organ Size, Middle Aged, Magnetic Resonance Imaging, Ganglion, medicine.anatomical_structure, Optic nerve, Female, medicine.symptom, Tomography, Optical Coherence, Adult, medicine.medical_specialty, Multiple Sclerosis, Adolescent, Neuroimaging, Asymptomatic, Sensitivity and Specificity, Retina, Lesion, Contrast Sensitivity, 03 medical and health sciences, Young Adult, Ophthalmology, medicine, Humans, Optic neuritis, Aged, business.industry, Optic Nerve, medicine.disease, eye diseases, 030104 developmental biology, Cross-Sectional Studies, Asymptomatic Diseases, Anisotropy, sense organs, Neurology (clinical), Atrophy, business, 030217 neurology & neurosurgery, Optic radiation
Abstract: ObjectiveTo evaluate the frequency of asymptomatic optic nerve lesions and their role in the asymptomatic retinal neuroaxonal loss observed in multiple sclerosis (MS).MethodsWe included patients with remitting-relapsing MS in the VWIMS study (Analysis of Neurodegenerative Process Within Visual Ways In Multiple Sclerosis) (ClinicalTrials.gov Identifier: 03656055). Included patients underwent optical coherence tomography (OCT), optic nerve and brain MRI, and low-contrast visual acuity measurement. In eyes of patients with MS without optic neuritis (MS-NON), an optic nerve lesion on MRI (3D double inversion recovery [DIR] sequence) was considered as an asymptomatic lesion. We considered the following OCT/MRI measures: peripapillary retinal nerve fiber layer thickness, macular ganglion cell + inner plexiform layer (mGCIPL) volumes, optic nerve lesion length, T2 lesion burden, and fractional anisotropy within optic radiations.ResultsAn optic nerve lesion was detected in half of MS-NON eyes. Compared to optic nerves without any lesion and independently of the optic radiation lesions, the asymptomatic lesions were associated with thinner inner retinal layers (p < 0.0001) and a lower contrast visual acuity (p ≤ 0.003). Within eyes with asymptomatic optic nerve lesions, optic nerve lesion length was the only MRI measure significantly associated with retinal neuroaxonal loss (p < 0.03). Intereye mGCIPL thickness difference (IETD) was lower in patients with bilateral optic nerve DIR hypersignal compared to patients with unilateral hypersignal (p = 0.0317). For the diagnosis of history of optic neuritis, sensitivity of 3D DIR and of mGCIPL IETD were 84.9% and 63.5%, respectively.ConclusionsAsymptomatic optic nerve lesions are an underestimated and preponderant cause of retinal neuroaxonal loss in MS. 3D DIR sequence may be more sensitive than IETD measured by OCT for the detection of optic nerve lesions.
Published: 2019

7. Exploration vasculaire non invasive des vaisseaux à destinée encéphalique

Author: X. Leclerc, J.-Y. Gauvrit, F. Eugène, J P Pruvo, and C. Gautier
Published: 2018

8. L’imagerie en tenseur de diffusion révèle des anomalies segmentaires de substance blanche spécifiques de la forme clinique d’épilepsie

Author: Gustavo Soto-Ares, Ph Derambure, X. Leclerc, Q. Vannod-Michel, Renaud Lopes, J.P. Pruvo, Grégory Kuchcinski, and William Szurhaj
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Objectif La presence d’anomalies structurelles des faisceaux de substance blanche a distance du foyer epileptogene serait un facteur de mauvais pronostic chirurgical chez les patients presentant une epilepsie pharmaco-resistante. Notre objectif est d’evaluer en DTI (diffusion tensor imaging) de maniere segmentaire les anomalies micro-structurelles de la substance blanche en fonction de la forme clinique d’epilepsie, au sein d’une cohorte de patients presentant une epilepsie pharmaco-resistante. Methodes Entre 2012 et 2017, 273 patients presentant une epilepsie refractaire ont beneficie d’un bilan prechirurgical de phase 1, comprenant une IRM cerebrale a 3 T (Philips Achieva, Philips Medical Systems, Best, the Netherlands) avec notamment une sequence DTI (TR = 12000ms, TE :55ms, 32 directions de gradient avec un facteur b = 1000s/mm2, taille de voxel : 2 mm3). Parmi ces patients, 79 presentant un bilan complet et un foyer epileptogene bien caracterise ont constitue notre groupe d’etude. Un groupe controle de 24 sujets sains etait egalement constitue. La tractographie des faisceaux de substance blanche etait realisee a l’aide du logiciel de tractographie globale et probabiliste TRACULA, apres debruitage des donnees, correction des distorsions geometriques et recalage lineaire. Les valeurs de fraction d’anisotropie (FA) et diffusivite moyenne (MD) le long de chaque faisceau de substance blanche etaient ensuite comparees en fonction du type d’epilepsie. Une p-value Resultats Parmi les 79 patients inclus, 69 presentaient une epilepsie temporale et 10 une epilepsie frontale. La MD etait plus sensible que la FA pour la detection d’anomalies micro-structurelles chez les patients epileptiques comparativement aux sujets sains. Les anomalies etaient plus diffuses chez les patients presentant une epilepsie temporale gauche comparativement aux patients presentant une epilepsie temporale droite. Chez les patients presentant une epilepsie temporale, les anomalies segmentaires significatives predominaient du cote lesionnel et dans le segment du faisceau connecte au lobe temporal. Les anomalies interessaient un nombre restreint de faisceaux chez les patients presentant une epilepsie frontale. Conclusion L’imagerie en tenseur de diffusion permet de reveler des anomalies microstructurelles segmentaires de la substance blanche au dela du foyer epileptogene, plus diffuses et plus severes pour les epilepsies temporales et gauches. L’impact de ces anomalies sur le pronostic chirurgical devra etre evalue sur une cohorte plus large de patients.
Published: 2019

9. Stroke-mimic et IRM de perfusion

Author: X. Leclerc, J. Hodel, B. Dutouquet, and J P Pruvo
Subjects: medicine.medical_specialty, business.industry, Stroke mimics, Status epilepticus, medicine.disease, Surgery, Internal medicine, medicine, Cardiology, Neurology (clinical), medicine.symptom, business, Perfusion, Stroke
Published: 2015

10. Reply

Author: J. Hodel, R. Blanc, E. Kalsoum, M. Zins, and X. Leclerc
Subjects: Arteriovenous Fistula, Humans, Radiology, Nuclear Medicine and imaging, Spin Labels, Neurology (clinical), Magnetic Resonance Imaging, Article
Published: 2017

11. Prédiction de l’évolution au long terme des troubles cognitifs post-AVC à partir de données d’IRM fonctionnelle de repos

Author: Jean-Pierre Pruvo, Stéphanie Bombois, Thibaut Dondaine, Christine Delmaire, X. Leclerc, Clément Bournonville, Régis Bordet, Hilde Hénon, and Renaud Lopes
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Introduction Malgre une forte prevalence, les mecanismes conduisant a l’apparition de troubles cognitifs apres un AVC sont tres mal connus. Lors de precedents travaux, nous avons identifie un reseau fonctionnel de repos altere chez des patients presentant un trouble cognitif 6 mois apres un premier accident ischemique 1. L’objectif de cette etude est de montrer l’effet predictif de ce reseau fonctionnel dans l’evolution de l’etat cognitif de patients 3 ans apres un AVC. Methodes 67 patients victimes d’un premier accident ischemique (cohorte STROKDEM, NCT01330160 ) sont suivis a 72 h, 6 et 36 mois apres l’AVC. Tous ont effectue une imagerie fonctionnelle de repos 6 mois post-AVC a l’aide d’une IRM Achieva 3 T (Phillips, Pays-Bas). Des examens clinique ( Tableau 1 ) et neuropsychologique evaluant la memoire, les fonctions executives, le langage et la perception visuelle, sont realises 6 et 36 mois apres l’AVC. L’evolution cognitive est definie par un z-score correspondant a la difference entre 6 et 36 mois post-AVC. La prediction de celle-ci est realisee a l’aide d’un algorithme d’apprentissage machine (ridge regression) prenant en entree les connections fonctionnelles du reseau prealablement determine et utilisant une validation croisee de type leave-one out comme mesure d’efficacite. La significativite de chaque prediction est evaluee a l’aide d’un modele null par permutations. Resultats A l’exception du langage, l’evolution de l’etat de la memoire, des fonctions executives et visuo-perceptives sont significativement predites par le reseau fonctionnel 6 mois apres l’AVC ( Fig. 1 , p Conclusion Cette etude montre l’interet de la connectivite fonctionnelle par IRM dans l’explication et la prediction de l’evolution de l’etat cognitif d’un patient au long terme apres un AVC.
Published: 2018

12. Rehaussement de la paroi des anévrismes intra-crâniens non rompus en IRM 3D-T1 Black Blood : impact de la taille anévrismale

Author: Nicolas Bricout, Thomas Personnic, Martin Bretzner, G. Kuchcinski, and X. Leclerc
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Introduction La signification du rehaussement de la paroi des anevrismes intra-crâniens non rompus en IRM 3-Tesla demeure aujourd’hui incertaine. L’objectif de cette etude etait d’evaluer la prevalence du rehaussement de la paroi anevrismale dans une cohorte de patients presentant un anevrisme non rompu avant decision therapeutique. Methodes Nous avons inclus retrospectivement les patients consecutifs avec anevrisme intracrânien non rompu adresses dans notre service pour imagerie cerebrale complementaire avant decision therapeutique entre novembre 2015 et avril 2017. Les donnees cliniques et d’imagerie incluant des sequences d’IRM 3D-T1 Turbo Spin Echo apres injection de gadolinium ont ete collectees. Resultats Parmi les 68 patients (81 anevrismes) inclus, un rehaussement de la paroi anevrismale etait objective pour 31 (45,6 %) patients et 34 (42,0 %) anevrismes. La taille de l’anevrisme etait fortement associee au rehaussement de la paroi (Odds Ratio 2,60 ; IC 95 % : 1,61–4,19, p = 0,001). Une valeur seuil de 4,1 mm etait predictive d’un rehaussement de la paroi de l’anevrisme avec une sensibilite de 82,4 % et une specificite de 85,1 %. Il n’etait pas retrouve d’association entre les caracteristiques cliniques et le rehaussement anevrismal. Conclusion Notre etude suggere que la taille de l’anevrisme est un determinant majeur du rehaussement de la paroi pour les anevrismes intra-crâniens non rompus.
Published: 2019

13. Maladie de Fabry

Author: X. Leclerc, A. Daghfous, E. Toledano, E. Kalsoum, F. Tempremant, J.-P. Pruvo, and T. Boulanger
Subjects: business.industry, Medicine, business
Published: 2015

14. Urgences neurologiques non traumatiques

Author: T. Gauthier, B Carsin-Nicol, J Y Gauvrit, Thomas Ronzière, X Leclerc, and J C Ferré
Subjects: business.industry, Medicine, business
Published: 2011

15. La présence d’une lésion infraclinique du nerf optique en 3D-Dir est associée aux critères diagnostiques de SEP selon McDonald 2010

Author: J P Pruvo, X. Leclerc, Patrick Vermersch, Nawal Hadhoum, Frédéric London, Olivier Outteryck, Hélène Zéphir, and Jérôme Hodel
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Introduction La localisation « nerf optique » n’est actuellement pas prise en compte dans les criteres de dissemination spatiale de sclerose en plaques (SEP). Objectif Evaluer la frequence de la localisation « nerf optique » infraclinique grâce a la sequence 3D-Double-Inversion-Recovery et mesurer ses liens avec les criteres de dissemination spatiale (DS) et temporelle (DT) de SEP selon McDonald revises en 2010. Methodes Entre novembre 2013 et aout 2016, 57 patients ayant presente un premier evenement inflammatoire demyelinisant (CIS) ont beneficie a 3 mois de la survenue de leur CIS d’une IRM cerebrale (3T-Achieva) comprenant des sequences 3D (T1, FLAIR et DIR). La presence d’une lesion inflammatoire silencieuse du nerf optique etait recherchee sur la sequence 3D-DIR. Resultats Parmi les 57 patients, 21 avaient presente une nevrite optique clinique (37 %) incluant deux cas d’atteinte bilaterale et 36 (63,1 %) avait au moins un hypersignal DIR sur un nerf optique. Tous les patients avec une NORB (n = 21) presentaient une lesion sur le nerf optique atteint alors que 22 patients presentaient au moins une lesion silencieuse du nerf optique, dont 3 de facon bilaterale (38,5 %, 25 nerfs optiques). L’atteinte silencieuse du nerf optique n’etait pas significativement associee aux criteres de DS de McDonald 2010 mais etaient significativement associes aux criteres de DT (p = 0,03) et aux criteres diagnostique de SEP selon McDonald 2010 (p = 0,017). Conclusions L’atteinte silencieuse du nerf optique au stade clinique le plus precoce de la SEP est frequente. Elle est associee a une plus importante activite inflammatoire IRM representee par la presence de lesions silencieuses rehaussees par le gadolinium. Il apparait pertinent de l’integrer dans les localisations topographiques evocatrices de SEP pour les criteres diagnostiques (MAGNIMS 2016).
Published: 2018

16. Traitement endovasculaire des AVC ischémiques de circulation antérieure avec le cathéter Sofia : expérience initiale au CHU de Lille

Author: Apolline Kazemi, Fouzi Bala, J.P. Pruvo, N. Nouri, X. Leclerc, A. El Khamlichi, Laurent Estrade, Thomas Personnic, and Nicolas Bricout
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Objectif La thrombectomie mecanique (TM) est desormais le traitement de reference des AVC ischemiques de circulation anterieure avec occlusion vasculaire proximale. Le developpement rapide de la technique a ete associe a la mise sur le marche de nombreux dispositifs medicaux dont l’evaluation est necessaire. Recemment, l’etude ASTER n’a pas montre de difference significative entre les 2 principales techniques : le stent retriever et la thrombo-aspiration. Le catheter Sofia est un catheter intermediaire et d’aspiration developpe pour le traitement endovasculaire des AVC. Le but de notre travail etait d’evaluer l’efficacite et la securite de l’utilisation du catheter d’aspiration Sofia dans la thrombectomie mecanique (TM) pour le traitement endovasculaire des AVC ischemiques de circulation anterieure. Materiels et methodes Les 100 premiers patients consecutifs ayant beneficie d’une TM avec un catheter Sofia au CHU de Lille de janvier 2016 a juin 2017 etaient identifies dans un registre clinique prospectif. Les caracteristiques initiales (score NIHSS, DWI-ASPECTS), les donnees angiographiques (site d’occlusion, score mTICI), l’imagerie a H24 (DWI-ASPECTS et hematome parenchymateux) et le pronostic a 3 mois (mRS) etaient recueillis. Resultats Cent patients (âge moyen de 69,7 ans, femmes 57 %) ont ete inclus. Le score NIHSS moyen a l’admission etait a 25 [1–38]. Le site de l’occlusion en arteriographie etait M1 dans 60 %, M2 dans 15 %, T carotidien dans 15 % et en tandem dans 10 % des cas. Le score ASPECTS initial median etait de 5–6 a j0. Le temps procedural moyen de la thrombectomie etait de 42 minutes. Nous avons utilise une technique d’aspiration seule dans 27 % des cas et associee a un stent retriever dans 73 % des cas. Un succes de reperfusion (TICI2b/3) etait obtenu dans 78 % des cas (mTICI3 = 49 %, mTICI2b = 29 %). Un bon pronostic fonctionnel (mRS 0–2) a 3 mois etait obtenu chez 25 % des patients. Conclusion Notre travail montre que les catheters d’aspiration Sofia utilises pour les thrombectomies mecaniques permettent d’obtenir de bons resultats angiographiques, une evolution clinique favorable avec un faible taux d’echecs et de complications.
Published: 2018

17. L’atrophie rétinienne silencieuse dans la SEP est liée à une atteinte infraclinique du nerf optique

Author: Olivier Outteryck, Renaud Lopes, J P Pruvo, Hélène Zéphir, Nawal Hadhoum, X. Leclerc, Patrick Vermersch, Jean-Baptiste Davion, and Julien Lannoy
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Introduction L’epaisseur retinienne est quantifiable de facon precise et reproductible en tomographie par coherence optique (OCT). Une perte axonale retinienne apparait dans les 3 a 6 mois qui suivent un episode clinique de nevrite optique. Elle predomine dans le quadrant temporal de la couche des fibres nerveuses de la retine peripapillaire (T-pRNFL). En dehors de tout episode de nevrite optique, une atrophie de le T-pRNFL est aussi classiquement rapportee. La litterature actuelle suggere que cette atrophie retinienne silencieuse soit la consequence de lesions inflammatoires des radiations optiques et d’une degenerescence retrograde transsynaptique. Objectif Evaluer le role de l’atteinte inflammatoire silencieuse du nerf optique dans la survenue de la perte axonale retinienne silencieuse au cours de la SEP. Methodes Etude monocentrique transversale evaluant de facon multimodale des patients atteints de SEP traites par natalizumab depuis plus de six mois au CHU de Lille. Chaque patient beneficiait d’une evaluation du handicap visuel, d’une evaluation OCT et IRM en sequences 3D (T1, FLAIR, DIR). Les logiciels ITKSNAP et Freesurfer etaient utilises pour la mesure de la charge lesionnelle T2 au sein des radiations optiques et pour la volumetrie du cortex visuel primaire. Les lesions du nerf optique etaient depistees et leur longueur mesuree sur la sequence 3D-DIR. Resultats Entre mars et septembre 2017, nous avons inclus 76 patients. Parmi les 152 yeux, 49 avaient un antecedent de NORB clinique. Parmi les 103 yeux indemnes de tout episode clinique de NORB (67,8 %), 51 presentaient au moins une lesion en hypersignal DIR du nerf optique (49,5 %) et 52 n’en presentaient pas. L’epaisseur de la T-pRNFL des sujets avec lesion(s) silencieuse(s) (n = 51) vs celle des sujets sans lesion silencieuse (n = 52) etaient significativement plus faible et associee a un cortex visuel primaire plus fin (28,1 vs 31,5 cm3 ; p = 0,001) et un handicap visuel plus important (2,5 % contrast : 0,72 versus 0,57 LogMAR, p = 0,0002). L’epaisseur de la T-pRNFL etaient significativement correlee a la longueur de la lesion du nerf optique (R2 = 0,48 ; p = 0,008) mais pas a la charge lesionnelle T2 des radiations optiques. Conclusions L’atteinte inflammatoire silencieuse du nerf optique mise en evidence sur la sequence 3D-DIR semble etre la principale cause de la perte axonale retinienne silencieuse de la SEP. L’OCT dans la SEP reste avant tout une fenetre sur le nerf optique.
Published: 2018

18. Hémorragie sous-arachnoïdienne anévrismale du sujet âgé. Participer à un essai clinique randomisé ?

Author: F. Proust, S. Bracard, L. Thines, X. Leclerc, G. Penchet, J. Bergé, J.-R. Vignes, B. Irthum, J. Gabrillargues, J. Chazal, B. Bataille, J. Drouinau, K. Mourier, F. Ricolfi, E. Gay, P. Bessou, M. Lonjon, J. Sedat, P. David, P. Lajaunias, X. Morandi, J.-Y. Gauvrit, I. Pelissou, F. Turjman, P.-H. Roche, H. Dufour, O. Levrier, E. Emery, P. Courthéoux, J. Laguarrigue, C. Cognard, T. Civit, and J.-P. Lejeune.
Subjects: business.industry, Medicine, Surgery, Neurology (clinical), business
Published: 2010

19. Thrombolyse IV et ischémie cérébrale : quelle imagerie en France en 2007 ?

Author: X. Leclerc, I. Klein, and Catherine Oppenheim
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Resume Objectif Recenser les pratiques d’imagerie cerebrale en France dans la prise en charge des accidents vasculaires cerebraux ischemiques (AVCI) avant thrombolyse. Materiel et methodes Un questionnaire de prise en charge des AVCI en imagerie a ete adresse debut 2007 a 80 unites neurovasculaires (UNV). Ce questionnaire concernait la methode d’imagerie cerebrale de premiere intention (scanner ou IRM), le protocole utilise ainsi que les criteres d’exclusion a la thrombolyse. Resultats Le scanner cerebral sans injection etait la modalite majoritairement utilisee (70 % des 53 centres repondeurs) avant decision therapeutique. Vingt-six centres (49 %) utilisaient les deux examens (scanner et IRM) et 12 centres (22 %) utilisaient systematiquement l’IRM en premiere intention. Ces 12 centres avaient une importante activite de thrombolyse ce qui explique que plus de la moitie des thrombolyses en 2006 etaient realisees sur les donnees de l’IRM. Au-dela de la troisieme heure, la thrombolyse IV etait effectuee majoritairement par les centres utilisant exclusivement l’IRM. L’enquete a montre que les criteres decisionnels etaient standardises au scanner alors qu’ils etaient plus heterogenes en IRM. De plus, la majorite des centres (28/38 reponses) estimait que l’IRM permettait parfois de surseoir a certaines contre-indications telles que l’absence d’horaire precis de debut des symptomes ou la presence de convulsions. Conclusion Cette enquete a montre que le scanner etait l’examen le plus souvent pratique avant decision therapeutique, avec un consensus sur les criteres decisionnels. L’enquete a egalement revele une evolution des pratiques d’imagerie avec une place de plus en plus importante de l’IRM en premiere intention.
Published: 2008

20. Première campagne d’évaluation des internes de radiodiagnostic en 2005 : résultats nationaux

Author: X Leclerc, A. Luciani, and J.N. Dacher
Subjects: Medical education, Modalities, Radiological and Ultrasound Technology, business.industry, Excellence, Teaching method, media_common.quotation_subject, Medicine, Radiology, Nuclear Medicine and imaging, business, media_common
Abstract: Teaching cannot exist without evaluation for three main reasons: it is indispensable to know interns' skills in radiodiagnosis and medical imaging during their training; it is useful to encourage excellence in interns to stimulate their learning; and finally, it is indispensable to provide feedback to teaching personnel so as to modify or correct teaching techniques, modalities, and programs. In September 2005, 260 interns in training participated voluntarily in the first national evaluation campaign. We will attempt to delineate the main lines of this initial experience as well as its limitations.
Published: 2007

21. Surgical views from three-dimensional digital subtraction angiography for the planning of aneurysm surgery

Author: Ph. Bourgeois, V. Le Thuc, Jean-Paul Lejeune, J.P. Pruvo, Laurent Thines, Christian Taschner, and X. Leclerc
Subjects: medicine.medical_specialty, Preoperative care, Imaging, Three-Dimensional, Aneurysm, medicine.artery, Preoperative Care, medicine, Humans, Radiology, Nuclear Medicine and imaging, Decision Making, Computer-Assisted, Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Angiography, Digital Subtraction, Reproducibility of Results, Intracranial Aneurysm, Volume rendering, Digital subtraction angiography, Perioperative, medicine.disease, Sagittal plane, Anterior communicating artery, medicine.anatomical_structure, Coronal plane, Feasibility Studies, Neurology (clinical), Radiology, business, Algorithms
Abstract: Aim To develop a semi-automatic protocol helping to present directly and quickly three-dimensional digital subtraction angiography (3D-DSA) data in an orientation that reproduces exactly the neurosurgeon's intraoperative view. Method Post-processing of 3D-DSA data (volume-rendering) was performed on an Integris workstation (Philips, Best); surgical views were obtained by visualization of the patient's head through a frontopterional approach: the 3D volume was turned 135° in the sagittal plane (around the X axis) and rotated by 45° and 60° in the coronal plane (around the Y axis). The protocol was evaluated on a consecutive series of nine patients who had ruptured or asymptomatic anterior circulation aneurysms requiring surgical treatment. Frontopterional views of angiographic 3D data were compared with intraoperative views. Results The proposed semi-automatic algorithm is simple, fast and reproducible, and displays the 3D data in an orientation identical to the intraoperative views. The surgical anatomy of the anterior communicating artery was best reproduced with a coronal rotation of 60°, with a coronal rotation of 45° for the other aneurysm locations. In each case, the surgical reconstructions allowed a more accurate analysis of the vascular anatomy around the aneurysm, and facilitated pre- and perioperative planning. Conclusion The present protocol displays angiographic 3D data in a projection that exactly reproduces the vascular anatomy through a frontopterional approach. It may help neurosurgeons to better anticipate any potential difficulties during access and clip-positioning arising due to the specific vascular anatomy of a given patient.
Published: 2007

22. Principes et techniques de quantification du degré de sténose carotide

Author: JP Pruvo, X. Leclerc, J.-Y. Gauvrit, and C. Gautier
Subjects: business.industry, Medicine, business
Published: 2007

23. Étude du parenchyme cérébral et des vaisseaux cervicoencéphaliques : nouvelles techniques d'IRM et scanner

Author: Christine Delmaire, P. Jissendi, S Caron, C Laurent, X. Leclerc, M. Lernout, Jean-Pierre Pruvo, M Faivre-Pierret, V. Le Thuc, and Jean-Yves Gauvrit
Subjects: business.industry, Medicine, Nuclear medicine, business
Published: 2007

24. Studio del parenchima cerebrale e dei vasi cervicoencefalici: nuove tecniche di RM e TC

Author: Jean-Yves Gauvrit, P. Jissendi, C Laurent, M Faivre-Pierret, J P Pruvo, S Caron, X. Leclerc, Christine Delmaire, V. Le Thuc, and M. Lernout
Subjects: media_common.quotation_subject, Art, Humanities, media_common
Abstract: Le nuove tecniche di neuroimmagine permettono un approccio funzionale e metabolico del cervello e possono essere utilizzate nella routine clinica a seguito o come complemento delle sequenze di neuroimmagine morfologica. Tra queste nuove tecniche, le sequenze con risonanza magnetica (RM) sensibili alla diffusione forniscono informazioni sullo spostamento delle molecole d’acqua e permettono di studiare l’organizzazione architettonica dei fasci di mielina, mentre le neuroimmagini funzionali di attivazione forniscono notizie sulla localizzazione delle zone corticali funzionali. Lo studio della microvascolarizzazione cerebrale mediante RM o TC di perfusione e utile non solo nella patologia vascolare per la valutazione della zona di penombra ischemica, ma anche nella patologia tumorale per valutare il grado di attivita tumorale. Infine, la spettroscopia RM (SRM) analizza le alterazioni del metabolismo cerebrale incontrate nella maggior parte delle malattie del sistema nervoso centrale e puo essere considerata come un marcatore diagnostico e prognostico della malattia. Per lo studio dei vasi, le nuove tecniche di RM e TC permettono di evitare il ricorso all’angiografia cerebrale in molte indicazioni e in particolare per la valutazione delle lesioni steno-occlusive aterosclerotiche. Nuove antenne multicanali di superficie possono essere utilizzate per lo studio RM ad alta risoluzione della placca d’aterosclerosi al fine di individuare placche ad alto rischio di un evento ischemico o placche vulnerabili. A livello endocranico, le nuove sequenze dinamiche in angio RM permettono lo studio delle malformazioni arterovenose cerebrali ed evitano il ricorso sistematico ai controlli arteriografici dopo terapia. Infine, uno studio in alta risoluzione delle arterie intracraniche puo essere realizzato in un tempo molto breve grazie alla TC multistrato di ultima generazione, in cui il trattamento delle immagini, semplice e rapido, permette di identificare aneurismi intracranici con sensibilita e specificita elevate.
Published: 2007

25. Exploration de l’ischémie cérébrale á la phase aiguë

Author: J.F. Meder, X. Leclerc, Michèle Hamon, Jean-Pierre Pruvo, Catherine Oppenheim, Olivier Naggara, and S Rodrigo
Subjects: Central nervous system disease, medicine.diagnostic_test, business.industry, Vascular disease, medicine, Magnetic resonance imaging, Cardiology and Cardiovascular Medicine, Nuclear medicine, business, medicine.disease, Stroke
Abstract: Resume Les patients pris en charge a la phase aigue d’un accident vasculaire cerebral (AVC) beneficient des progres de l’imagerie. L’Imagerie par Resonance Magnetique (IRM) permet de realiser precocement, des les premieres minutes, le diagnostic de lesions ischemiques. Celles-ci sont susceptibles de regresser si un traitement adapte, visant a lever l’occlusion arterielle, est mis en route dans les premieres heures. L’IRM evalue les possibilites de mise en route de ce traitement, ecartant notamment l’eventualite d’un AVC hemorragique, determine le pronostic et, enfin, participe au diagnostic etiologique. (J Mal Vasc 2006; 31: 252-259)
Published: 2006

26. The role of spiral CT for the assessment of the intracranial circulation in suspected brain-death

Author: G. Strecker, J.P. Pruvo, Christian Taschner, J. Savage, Jean-Yves Gauvrit, A. Vidal, and X. Leclerc
Subjects: Adult, Male, Brain Death, Middle Cerebral Artery, medicine.medical_specialty, Adolescent, Iohexol, Contrast Media, law.invention, law, medicine.artery, Image Interpretation, Computer-Assisted, medicine, Humans, Radiology, Nuclear Medicine and imaging, Spiral ct, Spiral, Radiological and Ultrasound Technology, business.industry, Blood flow, Middle Aged, Internal Cerebral Vein, Intensive care unit, Cerebrovascular Circulation, Clinical diagnosis, Middle cerebral artery, cardiovascular system, Female, Neurology (clinical), Radiology, business, Tomography, Spiral Computed, Circle of Willis
Abstract: Summary Background and purpose The aim of this study was to assess the role of spiral CT for the diagnosis of brain death. Methods Over a 12-month period, 15 patients that fulfilled the clinical criteria of brain death were referred from the intensive care unit to evaluate remaining intracranial blood flow by spiral CT. The clinical diagnosis was confirmed by an apnea test in all cases. Two phases of spiral CT were performed at 20 and 60 seconds after the start of contrast media injection. Qualitative analysis included the evaluation of vessel opacification (arteries and veins) by two radiologists in consensus. Results The cortical segments of the middle cerebral artery (MCA) were assessable in all patients, whereas the internal cerebral veins could not be evaluated in five patients due to artifacts or intracranial hemorrhage. Opacification of the major branches of the circle of Willis was observed in seven cases. Unilateral opacification of cortical branches of the MCA occurred in one. We did not observe bilateral enhancement of cortical MCA branches. The internal cerebral veins did not enhance in brain death. Conclusion The absence of internal cerebral vein opacification and the absence of bilateral enhancement of cortical MCA branches constituted the best criteria of brain death by contrast enhanced spiral CT.
Published: 2006

27. Contents Vol. 22, 2006

Author: Marta Rubiera, Izumi Oki, Pierre-Jean Touboul, David S Liebeskind, Askar Ghorbani, Toshisuke Sakaki, L. Korsholm, Rebecca F. Liberman, Noriko Salamon, Takao Urabe, J.P. Lejeune, Jacek Staszewski, Bogdan Brodacki, Hashem Shaltoni, Andrew P. Goldberg, Shigeru Fujimoto, S. Andrew Josephson, Claudia Chaves, Takehito Hayakawa, Jerzy Kotowicz, Aytekin Akyuz, Pablo Villablanca, Feng-Cheng Lin, Pranab Das, Abdolmehdi Baghaei, Kazunori Toyoda, Yasushi Okada, Adam Stępień, John D. Sorkin, Ching-Kuan Liu, E. Bernd Ringelstein, Monisha Dutta, Luigi Canciani, Sabri Batun, Ryota Tanaka, Kazimierz Tomczykiewicz, L. Thines, Tobias Poeplau, Steven R. Steinhubl, Chun-Hung Chen, Richard F. Macko, Christine M. Glastonbury, Carlos A. Molina, Hugues Chabriat, Shindokht Hosseini, Jennifer Pary, Patrizio Prati, Terubumi Watanabe, Frederick M. Ivey, James C. Grotta, Miki Komine-Kobayashi, Marzena Staszewska, Martin A. Ritter, Tomonori Okamura, X. Leclerc, Hirotsugu Ueshima, Juro Jinnouchi, Diego Vanuzzo, J.P. Mohr, Nancy K. Hills, Jun-ichi Iida, A. von Heijne, Norikiyo Nishikawa, Max Wintermark, Stephan P. Kloska, J.M. Wardlaw, Anne Schaefer, Marie-Germaine Bousser, Claire Gobron, C. Weimar, Giovanni Bader, Yoshikuni Kita, Bernadetta Moser, Letizia C.L. Antonietti, Mehmet Tatli, Shahram Oveisgharan, Akira Okayama, Lorenza Pilotto, Kinan Hreib, Grace M. Lee, Felix Adler, Shahin Shirani, Setsuro Ibayashi, José M. Ferro, Markku Kaste, Kenta Fujimoto, Jeffry R. Alger, Zsolt Garami, Nerses Sanossian, Hideaki Iwahashi, Yuan-Han Yang, Maurizio Ruscio, C. Taschner, John Y. Choi, Nizzal Sarrafzadegan, H. Mickley, Kazuo Yamashiro, Darius G. Nabavi, Rainer Dziewas, P. Bourgeois, Yoshikuni Mizuno, Shoichiro Kawaguchi, Marc D. Malkoff, Louis R. Caplan, Lucio Mos, Marco Casaroli, C. Lucas, Doojin Kim, K. Kraywinkel, Andrei V. Alexandrov, Lemuel A. Moyé, Gregory Allam, Seiji Gotoh, Elias Hanna, Brian M. Garrity, Alice S. Ryan, S. Claiborne Johnston, Hideaki Mishima, Charlene E. Hafer-Macko, Anand Viswanathan, F. Zairi, Aslan Guzel, Poyin Huang, Yosikazu Nakamura, Ruey-Tay Lin, J.K. Jensen, Yoko Yokoyama, M. Maschke, S. Bak, H.-C. Diener, Georg Röggla, Walter Heindel, Jeffrey L. Saver, Tannaz Razinia, S.R. Kristensen, Akbar Soltanzade, and Bruce Ovbiagele
Subjects: Neurology, Traditional medicine, business.industry, Medicine, Neurology (clinical), Cardiology and Cardiovascular Medicine, business
Published: 2006

28. Applications de l’arm dynamique dans la pathologie vasculaire du système nerveux central

Author: Catherine Oppenheim, François Nataf, J.-Y. Gauvrit, J.P. Pruvo, J. Savage, J.-F. Meder, Nicolas Reyns, and X. Leclerc
Subjects: Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Phase contrast microscopy, Hemodynamics, Image subtraction, Gold standard (test), medicine.disease, Magnetic resonance angiography, law.invention, Intracranial vascular, Venous thrombosis, Catheter angiography, law, cardiovascular system, Medicine, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Neurology (clinical), business, Nuclear medicine
Abstract: Conventional catheter angiography (CCA) remains the gold standard for the evaluation of most intracranial vascular malformations. MRA techniques such as Time of Flight, Phase Contrast or 3D contrast-enhanced MRA, provide anatomic evaluation but without hemodynamic information. Recently developed, dynamic MRA is based on dynamic acquisition of images and image subtraction; these two principal characteristics produce images comparable to those obtained by CCA. The purpose of this review is to explain the principles, advantages and drawbacks of this technique in the evaluation of arteriovenous malformations, arteriovenous fistulas, aneurysms and venous thrombosis.
Published: 2005

29. Imagerie vasculaire non invasive et malformations artérioveineuses cérébrales

Author: Nicolas Reyns, Denis Trystram, J.-Y. Gauvrit, X. Leclerc, J.P. Pruvo, and J.-F. Meder
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Resume L’evaluation en imagerie des malformations arterioveineuses (MAV) cerebrales necessite la visualisation selective des differents compartiments de la lesion afin de decider de la strategie therapeutique. L’angiographie cerebrale reste la methode de reference pour l’analyse anatomique des vaisseaux intracrâniens mais les techniques d’imagerie non invasives semblent constituer d’excellentes alternatives. L’angioscanner spirale est rarement realise en raison de la necessite d’injecter de l’iode et de son caractere irradiant. L’angiographie par resonance magnetique (ARM) apporte des informations interessantes et peut etre realisee selon plusieurs techniques : temps de vol sans ou avec injection de gadolinium, contraste de phase, acquisition tridimensionnelle en echo de gradient T1 apres injection de gadolinium et, plus recemment, ARM dynamique avec injection. L’objectif de cette revue est de resumer le principe des differentes techniques d’imagerie vasculaire non invasives et d’etudier l’apport de celles-ci a l’etude des MAV.
Published: 2004

30. Céphalées dans un contexte d’urgence

Author: J.-Y. Gauvrit, Catherine Oppenheim, Thierry Moulin, X. Leclerc, J.-F. Meder, J.P. Pruvo, and J. Savage
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Resume Les cephalees constituent un des motifs les plus frequents de consultation. Leurs causes sont extremement diverses. Il est tres important dans un premier temps de preciser les caracteristiques de la douleur et les signes d’accompagnement afin de distinguer les cephalees primaires ne necessitant pas d’examen d’imagerie et dont les causes les plus frequentes sont les migraines et les cephalees de tension, des cephalees secondaires attribuees a une cause organique et necessitant des explorations plus approfondies. En cas de suspicion de cephalees secondaires ou symptomatiques, l’imagerie tient une place tres importante dans le bilan etiologique. Son objectif en urgence est de rechercher une affection susceptible d’engager le pronostic vital.
Published: 2004

31. Les urgences neurologiques

Author: Patrick Vermersch, X. Leclerc, D. Leys, B. Pertuzon, Luc Defebvre, C. Lucas, and J.P. Pruvo
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Resume Les urgences neurologiques constituent une activite consequente dans les services d’accueil des centres hospitaliers. Les pathologies rencontrees sont tres diverses et sont susceptibles d’entrainer une morbi-mortalite non negligeable si la prise en charge medicale n’est pas optimale des les premieres heures. Nous detaillerons dans cet article les urgences neurologiques les plus frequemment rencontrees et ou le recours aux examens neuroradiologiques est souvent demande, tels les accidents vasculaires cerebraux, les pertes de connaissance, les crises convulsives, les cephalees, les etats confusionnels, les troubles de vigilance, le syndrome meninge et la paralysie faciale. Nous n’avons pas traite le syndrome medullaire aigu (exclus de cet ouvrage) et les troubles aigus visuels (traites dans un autre chapitre).
Published: 2004

32. Imagerie radiologique des sténoses carotidiennes asymptomatiques : quand ? Comment ? Analyse critique

Author: X. Leclerc, J.Y. Gauvrit, J F Meder, and Jean-Pierre Pruvo
Subjects: Gynecology, medicine.medical_specialty, business.industry, Medicine, Cardiology and Cardiovascular Medicine, business
Abstract: Resume Une stenose asymptomatique de l’artere carotide interne necessite un bilan d’imagerie le moins invasif possible dont les objectifs sont non seulement de quantifier le degre de stenose mais egalement d’analyser la plaque d’atherome et d’etudier le retentissement de cette stenose sur le parenchyme cerebral. Les etudes publiees ont montre la fiabilite de l’ARM et de l’angioscanner spirale pour l’analyse de la lumiere vasculaire. Il existe cependant un consensus sur l’association echo-doppler et ARM en raison du caractere non invasif de ces examens et de l’etude complete a la fois cervicale et encephalique. Les avancees recentes en IRM permettent egalement d’envisager une analyse conjointe de la paroi vasculaire afin de detecter les plaques a risque et optimiser la prise en charge therapeutique.
Published: 2004

33. Imagerie radiologique des sténoses carotidiennes asymptomatiques : quand ? Comment ? Analyse critiqueA critical appraisal of diagnostic imaging techniques in asymptomatic carotid stenosis

Author: J F Meder, X. Leclerc, Jean-Pierre Pruvo, and J.Y. Gauvrit
Subjects: medicine.medical_specialty, business.industry, medicine.disease, Asymptomatic, Critical appraisal, Stenosis, Therapeutic approach, medicine.artery, medicine, Medical imaging, Radiology, Internal carotid artery, medicine.symptom, Ultrasonography, Cardiology and Cardiovascular Medicine, business, Arterial lumen
Abstract: Asymptomatic stenosis of the internal carotid artery requires a non-invasive imaging work-up. The objectives include the quantification of the degree of stenosis, the analysis of the atherosclerotic plaque and the consequences of this stenosis on the brain tissue. Previous studies showed the reliability of MR angiography and spiral CT for the assessment of the arterial lumen. However, the consensus is based on the association of ultrasonography and MRA because of the non-invasive approach of these examinations that allow a complete evaluation of both the extracranial and the intracranial vessels. Recent advances in MRI will probably allow to simultaneously analyze the arterial wall in order to detect the plaques at risk and to optimize the therapeutic approach.
Published: 2004

34. Diagnostic par angioscanner de la mort encéphalique: recommandations de la Société française de neuroradiologie (SFNR)

Author: X. Leclerc
Subjects: Radiological and Ultrasound Technology, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Neurology (clinical), business
Published: 2007

35. Vertige d’aggravation brutale chez un patient de 28ans

Author: E. Toledano, A. Daghfous, E. Kalsoum, J.-P. Pruvo, T. Boulanger, F. Tempremant, and X. Leclerc
Published: 2015

36. 3D-SWAN-Sequenz im MRT bietet Verbesserung

Author: X Leclerc, W Khaled, and J Hodel
Published: 2015

37. Embolie graisseuse cérébrale après traumatisme fermé de la jambe

Author: E Wiel, M Fleyfel, O Godefroy, P Adnet, J Onimus, and X Leclerc
Subjects: Gynecology, medicine.medical_specialty, Anesthesiology and Pain Medicine, Cerebral embolism, business.industry, Medicine, General Medicine, business
Abstract: Resume Un jeune homme de 21 ans, victime d'un accident du travail, a ete hospitalise pour fracture complexe non deplacee du tiers superieur du tibia droit, sans traumatisme crânien associe. Son etat hemodynamique etait stable. Une contention par plâtre cruropedieux a ete effectuee. Deux heures apres son admission, l'examen clinique mettait en evidence une obnubilation (score de Glasgow a 10) d'apparition brutale, sans signe de focalisation. Quatre heures apres l'admission, une aggravation des troubles de conscience (score de Glasgow a 7), accompagnee d'une crise convulsive hemicorporelle gauche, etait notee. La tomodensitometrie cerebrale initiale et la ponction lombaire etaient normales. La radiographie pulmonaire etait normale. Des petechies sur le tronc et l'abdomen etaient progressivement apparues. Une thrombopenie et un allongement du temps de prothrombine etaient notes. L'imagerie par resonance magnetique realisee a la 27 e heure montrait des hypersignaux en T2 au niveau du tronc cerebral et des noyaux gris centraux, evoquant une embolie graisseuse. Au fond d'œil, une hemorragie papillaire en flammeches a ete observee. Le diagnostic d'embolie graisseuse cerebrale a ete conforte par le lavage broncho-alveolaire mettant en evidence des inclusions lipidiques macrophagiques. L'interet de cette observation est de rappeler la possibilite de forme neurologique predominante d'embolie graisseuse et l'interet diagnostique de l'imagerie par resonance magnetique realisee precocement apres le traumatisme.
Published: 1997

38. Diagnostic et surveillance des dissections des artères cervicales

Author: J.-Y. Gauvrit, Emmanuel Touzé, J.L. Mas, Thierry Moulin, J.-F. Meder, F. Charbonneau, X. Leclerc, and Serge Bracard
Subjects: Radiological and Ultrasound Technology, Radiology, Nuclear Medicine and imaging, Neurology (clinical)
Abstract: Resume Introduction l’objectif de cette etude etait de determiner, l’evolution des pratiques radiologiques pour le diagnostic, la surveillance et l’etude du retentissement cerebral des dissections des arteres cervicales (DAC). Materiel et methodes de 1995 a 2001, une enquete retrospective, repartie dans 24 centres hospitaliers a ete menee. Un questionnaire a choix multiples etait adresse a chaque centre comprenant les donnees cliniques et d’imagerie pour le diagnostic et la surveillance des DACs. Resultats l’etude comprenait 459 patients, soit un total de 384 arteres carotides et 170 arteres vertebrales dissequees. Pour le diagnostic de DAC, 4,85 examens ont ete, en moyenne, realises par patient. Une exploration morphologique cerebrale, par scanner ou IRM, etait effectuee chez tous les patients, excepte trois. L’echoDoppler cervical etait l’examen le plus frequemment retrouve sur l’ensemble de la periode d’observation (87 % des patients). En 1995, l’arteriographie etait pratiquee de facon systematique chez tous les patients alors que cet examen n’etait plus prescrit que chez 31,2 % des patients en 2001. Elle a ete progressivement remplacee par l’IRM et l’ARM cervicales qui representaient environ 60 % des examens en 2001. L’association echoDoppler cervical, IRM en coupes axiales et ARM cervicale etait retrouvee chez 39,6 % des patients en 2001. Une exploration des vaisseaux intracrâniens etait pratiquee dans 40 % des cas par echoDoppler trans-crânien et dans 30 % des cas par ARM. Pour le suivi des patients, le nombre moyen d’examens par patient etait de 1,4. La majorite de ces examens etait des echoDopplers et/ou des ARM cervicales. Conclusion le diagnostic et le suivi en imagerie des DAC sont assures desormais par une association de techniques non invasives.
Published: 2005

39. Anesthésie-réanimation pour occlusion endovasculaire des anévrismes intracrâniens rompus par des spires électriquement détachables

Author: A Drizenko, R Krivosic-Horber, S Frangie, X Leclerc, S Doumith, and J.-P. Pruvo
Subjects: medicine.medical_specialty, medicine.diagnostic_test, Ruptured aneurysms, Vascular disease, business.industry, medicine.medical_treatment, Interventional radiology, General Medicine, Controlled ventilation, medicine.disease, Endovascular occlusion, Surgery, Anesthesiology and Pain Medicine, Aneurysm, Anesthesia, medicine, General anaesthesia, Embolization, business
Abstract: The endovascular occlusion of ruptured intracranial aneurysms with electrically detachable coils is a therapeutic approach which seems to be a promising technique. General anaesthesia is considered as being the most adapted for its realisation, as its provides complete immobility and as controlled ventilation and extended monitoring offer optimal conditions for undelayed treatment of haemorrhagic and thromboembolic complications. The available equipment should be the same as that used for conventional surgical treatment of ruptured aneurysms. Anticoagulation is required to prevent thromboembolic complications during and after the procedure. Most teams administer heparin.
Published: 1996

40. MRI of myelitis

Author: X. Leclerc, P. Jissendi, Marc Zins, Outteryck O, Hodel J, and Jean-Pierre Pruvo
Subjects: lcsh:Medical physics. Medical radiology. Nuclear medicine, medicine.medical_specialty, Neuromyelitis optica, business.industry, lcsh:R895-920, Multiple sclerosis, Myelitis, medicine.disease, Magnetic Resonance Imaging, Transverse myelitis, Diagnosis, Differential, Spinal Cord, Humans, Medicine, In patient, Radiology, business
Abstract: The diagnosis of myelitis relies on MRI. The purpose of this review is to describe the imaging findings in patients with myelitis through clinical cases. MR findings in Multiple Sclerosis, Neuromyelitis Optica and others Transverse Myelitis are highlighted.
Published: 2012

41. Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain

Author: H. Hattig, C. Delli Pizzi, M. C. Addonizio, Michelle Davis, A. R. Giovagnoli, L. Florensa, M. Roth, J. de Kruijk, Francisco Lacruz, Ph. Dewailly, A. Toygar, C. Avendano, P.P. De Deyn, J. F. Hurtevent, F. Lomeila, T. W. Wong, Gordon T. Plant, M. Bud, H. J. Willison, DH Miller, D. W. Langdon, R. Cioni, J. Servan, A. Kaygisiz, E. Racadot, D. B. Schens, E. Picciola, L. Falip, C. Bouchard, J. Jotova, A. Jorge-Santamaria, P. Misra, A. Dufour, C. P. Panagopoulos, A. Venneri, B. Sredni, B. Angelard, M. Janelidze, M. Carreno, J. Obenberger, J. Pouget, H. W. Moser, R. Kaufmann, J. A. Molina, D. Linden, A. Martin Urda, E. Uvestad, A. Krone, J. P. Cochin, J. Mallecourt, A. Cambon-Thomsen, K. Violleau, P. Osschmann, A. M. Durocher, E. Bussaglia, D. M. Danielle, H. Efendi, C. Van Broeckhoven, K. G. Jordan, W. Rautenberg, C. Iniguez, J. M. Delgado, Graham Watson, M. Lawden, Gareth J. Barker, K. Stiasny, James T. Becker, G. Campanella, E. Peghi, A. Poli, A. Haddad, T. Yamawaki, Giacomo P. Comi, S. Sotgiu, B. Ersmark, A. Pomes, M. Ziegler, P. Ferrante, P. Ruppi, H. KuÇukoglu, R. Bouton, U. K. Rinne, P. Vieregge, M. Dary, P. Giunti, Peter J. Goadsby, S. Jung, E. Secor, A. Steinberg, N. Vila, M. A. Hernandez, M. Cursi, A. Enqelhardt, A. Engelhardt, J. Veitch, F. Di Silverio, F. Arnaud, B. Neundörfer, R. Brucher, Dominique Caparros-Lefebvre, B. Meyer, Marianne Dieterich, M. H. Snidaro, R. Gomez, R. Cerbo, M. Ragno, J. M. Vance, S. Nemni, A. Caliskan, F. Barros, I. Velcheva, D. Ceballos-Baumann, V. Barak, A. Avila, N. Antonova, F. Resche, S. Pappata, L. Varela, S. R. Silveira Santos, A. Cammarota, L. Naccache, Y. Nara, E. Tournier-Lasserves, R. Mobner, T. Chase, A. Ensenyat, J. Ulrich, G. Giegerich, M. Rother, M. Revilla, N. Nitschke, K. Honczarenko, E. Basart Tarrats, J. Blin, B. Jacob, J. Santamaria, S. Knezevic, J. L. Castillo, M. Antem, J. Colomer, O. Busse, Didier Hannequin, S. Carrier, J. B. Ruidavets, C. Rozman, J. Bogoussslavsky, J. Pascual Calvet, E. Monros, J. M. Polo, M. Zucconl, Javier Muruzabal, R. R. Allen, R. Rivolta, K. Haugaard, A. Nespolo, K. Hoang-Xuang, G. Bussone, T. Avramidis, E. Corsini, Christiana Franke, T. Vinogradova, H. Boot, K. Vestergaard, G. H. Jansen, N. Argentino, M. Raltzig, W. Linssen, Mark B. Pepys, P. Roblot, L. Lauritzen, E. Fainardi, D. Morin, T. X. Arbizu Urdiain, J. Wollenhaupt, S. Bostantjopoulou, G. Pavesi, A. D. Forman, Giovanni Fabbrini, D. Jean, J. J. Archelos, M. I. Blanchs, M. Del Gobbo, Anna Carla Turconi, Ch. Derouesné, Elio Scarpini, A. Visbeck, P. Castejon, J. P. Renou, F. Mounier-Vehier, G. Potagas, Ch. Duyckaerts, A. Filla, R. Schneider, G. Ronen, K. Nagata, J. P. Vedel, A. Henneberg, G. van Melle, C. Baratti, H. Knott, M. C. Prevett, A. Bes, B. Metin, Jos V. Reempts, L. Martorell, Mefkure Eraksoy, H. O. Handwerker, D. S. Younger, O. Oktem, D. Frongillo, C. Soriano-Soriano, L. Niehaus, F. Zipp, A. Tartaro, S Newman, R. H. Browne, P. Davous, R. Sanchez, M. Muros, M. E. Kornhuber, A. Lavarone, M. Mohr, M. R. Garcia, S. Russell, H. Kellar-Wood, M. R. Tola, B. Ostermeyer, Ch. Tzekov, K. Sartor, E. B. Ringelstein, P. P. Gazzaniga, Paul Krack, H. Fidaner, H. Rico, T. Dbaiss, F. Alameda, E. Torchiana, L. Rumbach, I. Charques, J. M. Bogaard, C. D. Frith, L. J. Rappelle, R. Brenner, A. Joutel, K. Fuxe, G. HÄcker, M. J. Blaser, J. Valls-SolÇ, G. Ulm, M. Alberdi, A. Bock, F. W. Bertelsmann, U. Wieshmann, J. Visa, J. R. Lupski, D. D'Amico, L. M. P. Ramos, A. A. Vanderbark, R. Horn, M. Warmuth, Dietmar Kühne, Mark S. Palmer, C. Ehrenheim, E. Canga, S. Viola, O. Scarpino, P. Naldi, R. Almeida, A. A. Raymond, J. Gamez, Stephan Arnold, A. DiGiovanni, J. Dalmau, C. C. Chari, H. F. Beer, J. C. Koetsier, J. Iriarte, E. Yunis, J. Casadevall, E. Le Guern, E. Stenager, S. R. Benbadis, J. M. Warter, F. Burklin, I. Theodorou, L. Johannesen, G. A. Graveland, X. Leclerc, I. Vecchio, L. Ozelius, G. Nicoletti, R. K. Gherardi, E. Esperet, M. L. Delodovici, F. Cattin, F. Paiau, Giorgio Sacilotto, C. A. J. Broere, D. Chavdarov, J. P. Willmer, C. H. Hawkes, Th. Naegele, E. Ellie, E. Dartigues, M. J. Guardiola, S. Hesse, Z. Levic, Marco Rovaris, P. Saugeir-Veber, B. A. Yaqub, H. F. Durwen, R. Larumbe, J. Ballabrina, M. Sendtner, J. Röther, M. Horstink, C. Kluglein, M.P. Montesi, H. Apaydin, J. Montoya, E. Waubant, Ch. Verellen-Dunoulin, A. Nicolai, J. Lopez-Delval, R. Lemon, G. Cantinho, E. Granieri, A. Zeviani, Wolfgang H. Oertel, U. Ficola, V. Di Piero, V. Fragola, K. Sabev, M. V. Guitera, I. Turki, F. Bolgert, P. Ingrand, J. M. Gobernado, L. M. E. Grimaldi, S. Baybas, B. Eymard, Y. Rolland, Y. Robitaille, Ta. Pampols, P. J. Koehler, A. Carroacedo, J. Vilchez, S. Di Vittorio, I. R. Rise, T. Nagy, M. Kuffner, E. Palazzini, A. Ott, J. Pruim, T. X. Arbizu, E. Manetti, C. Cervera, S. Felber, G. Gursoy, J. Scholz, G. A. Buscaino, M. S. Chen, A. Pascual, J. Hazan, J. U. Gajda, J. G. Cea, G. Bottini, G. Damalik, F. Le Doze, G. Bonaldi, J. M. Hew, C. Messina, A. M. Kennedy, J. M. Carney, N. M. F. Murray, M. Parent, M. Koepp, V. Dimova, D. De Leo, K. Jellinger, G. Salemi, S. Mientus, M. L. Hansen, F. Mazzucchelli, J. Vieth, M. Mauri, E. Bartels, L. Johannsen, C. Humphreys, J. Emile, D. N. Landon, E. Kansu, R. Sanchez-Pernaute, Rsj Frackowiak, M. Gonzalez Torres, L. Oller, C. Machedo, J. Kother, M. Billiard, H. Durak, T. Schindler, A. Frank, A. Uncini, A. Sbriccoli, C. Farinas, D. W. Paty, N. Fast, A. T. Zangaladze, A. Kerkhofs, J. M. Pino Garcia, I. De la Fuente, B. Marini, L. Gomez, I. Rubio, Alessandra Bardoni, C. Brodie, P. Acin, U. Sliwka, S. A. Hawkins, S. Tardieu, F. Vitullo, J. M. Pereira Monteino, R. Gagliardi, T. Jezewski, A. Cano, T. Lempert, F. Abad Alegria, G. Rotondo, D. Ince, C. Martinez Parra, Y. Huang, H. Luders, Y. Steinvil, F. G. A. Van Der Meche, R. Bianchi, A. Sanchez, T. Sevilla, J. M. Ketelslegers, A. Domzal-Stryga, M. Pandolfo, M. O. Josse, K. W. Neff, I. Blanco, G. W. Bruyn, O. W. Witte, J. L. Thibault, G. Andersen, J. Pariset, A. Marcone, R. J. M. Lane, A. Hofman, M. Verin, T. Matilla, P. Bedoucha, J. Roche, M. Lai, M. Collard, A. Ugarte, F. Gallecho, D. Silbersweig, C. Kennard, J. P. Azulay, T. W. Ho, P. L. I. Dellemijn, R. Girardello, F. Baas, B. Voss, F. Rozenberg, E. M. Brocker, V. Stanev, A. A. J. Soeterboek, A. Marra, A. Rey, E. Ertem, M. Sawradewicz-Rybak, J. De Keyser, P. Cavallari, F. Proust, Y. Chevalier, H. C. Hansen, D. Leys, C. A. Davie, K. Hoang-Xuan, C. Bairati, H. van Crevel, Thomas T. Warner, B. Bompais, A. Dobbeleir, T Campbell, C. Macko, C. J. M. Klijn, M. Dussallant, T. P. Berlit, W. Rozenbaum, M. J. van den Bent, W. A. Rocca, M. Muller, H. Hundemer, U. Zifko, M. Campera, F. Drislane, D. Ranoux, T. M. Kloss, Anil Kumar, I. Ruolt, C. Bargnani, B. Marescau, N. A. Losseff, S. Notermans, B. Kint, E. T. Burke, C. Aykut, J. Matias Guiu, P. Maquet, T. Drogendijk, M. Leone, K. von Ammon, M. Pepeliarska, C. Prados, L. DiGiamberardino, T. Logtenberg, G. Lenoir, I. Castaldo, Damhaut, M. Radionova, G. Sirabian, R. Navon, Giovanni Antonini, K. Al Moutaery, E. Chamas, R. Schönhuber, M. Giannini, B. Debilly, I. Labatut, H. Henon, J. A. Egido, M. Baudrimont, J. N. Lorenzo, J. E. C. Bromberg, R. Antonacci, J. J. Vilchez, T. Moulin, B. Rautenstrauss, Giovanni Meola, J. Noth, S Mammi, P. Laforet, F. Lopez, C. Gehring, S. Bort, G. Rancurel, D. Decamps, S. Kostadinova, Y. Shapira, B. Neundoerfer, D. Chavrot, M. Solimena, J. P. Salier, W. Deberdt, R. Hoff-Jörgensen, A. Messina, S. Meairs, G. Rosoklija, E. Nelis, I. Bertran, C. Ertekin, J. Lohmeyer, Mitermayer Galvao dos Reis, L. Calo, E. Maccagnano, A. P. Hays, J. Verlooy, M. G. Forno, T. Blanco, L. Bail, Gabriella Silvestri, J. Montero, F. Bertrand, R. T. Ghnassia, C. Besses, T. Sereghy, F. Shalit, G. Bogliun, S. Braghi, St. Baykouchev, C. Franke, A. Lasa, L. C. Archard, J. Kriebel, S. Shaunak, M. Nocito, Alexander Tsiskaridze, E. Manfredini, T. Seigal, David G. Gadian, M. Barlas, J. D. Degos, C. Seeber, J. Caemert, J. L. Mas, R. B. Pepinsky, M. G. D'Angelo, N. Baumann, S. Yorifuji, H. P. Endtz, M. A. Cassatella, R. A. C. Hughes, V. Golzi, A. Bittencourt, A. Ferreira, M. Sanson, C. Alper, M. Vermeulen, M. A. A. van Walderveen, E. Alexiou, C. H. Lucas, M. Fiorelli, Y. N. Debbink, R. Gil, S. Congia, T. Banerjee, J. M. Bouchard, A. N. Pinto, A. Ceballos-Baumann, G. Grollier, P. I. M. Schmitz, M. D. Catata, N. Lahat, N. S. Rao, P. Papathanasopoulos, J. Valls-Solé, D. Claus, G. Schroter, A. Castro, C. Videbaek, R. Martinez Dreke, A. D. Platts, M. Hermesl, A. C. PeÇanha-Martins, M. Cardoso Silva, P. Masnou, M. J. A. Tanner, Ch. Confavreux, B. Mishu, H. Rasmussen, L. Valenciano, Carlo Pozzilli, S. W. Li, V. Salzman, Y. Vashtang, Massimo Franceschi, M. Severo, G. Deuschl, S. Setien, G. Mariani, A. Protti, J. Castillo, M. J. B. Taphoorn, M. Frontali, I. Milonas, D. Decoq, J. A. Navarro, S. Castellvi-Pel, C. Ertikin, M. Urtasun, Y. Lajat, B. E. Kendall, E. Verdu, B. Gueguen, E. Boisen, R. Couderc, A Danek, JM Stevens, F. Nicoli, L. Feltri, M. L. Vazquez-Andre, J. A. Morgan-Hughes, L. D'Angelo, F. Y. Liew, L. F. Pascual, J. Patrignani Ochoa, Vittorio Martinelli, J. Cophignon, L. Zhang, S. Martin, J. F. Meder, H. C. Buschmann, L. Bertin, J. van Gijn, A. Barreiro, A. Cools, C. Leon, A. Berod, E. A. Anllo, E. Zanette, L. Petrov, R. Barona, B. Gallicchio, P. J. Cozzone, N. Diederich, G. Cancel, L. Schelosky, P. Orizaola, K. Yulug, S. Ozer, Valeria A. Sansone, B. Guiraud-Chaumeil, K. Voigt, P. Labauge, M. Eoli, J. Zhu, J. Aguirre, M. Ferrarini, B. Zyluk, E. Planas, A. Cadilha, C. Tortorella, H. Bismuth, C. E. Counsell, A. Laun, A. Ferlini, Rio J. Montalban, N. Biary, L. Becker, M. Fardeau, M. Poloni, V. M. S. de Bruin, C. Fornada, J. Barros, E. Ganzmann, E. Touze, D. Wallach, J. Peila, H. Fujimura, M. T. Iba-Zizen, G. Macchi, C. Villoslada, R. Gouider, Ph. Rondepierre, P. Grummich, P. Chiodi, C. Conte, M. Michels, P. Annunziata, G. Semana, C. Sommer, J. Vajsar, D. Zekin, J. Kulisevsky, David G. Munoz, B. Jacotot, M. Magoni, A. Luxen, T. Garcia-Silva, S. Di Cesare, Christophe Tzourio, M. Gomori, I. Picomell, L. Santoro, F. Villa, Giovanni Pennisi, T. Ribalta, J. M. Molto, L. Marzorati, P. Loiseau, F. Gemignani, A. Gironell, J. Wissel, A. Prusinski, F. Cailloux, P. Villanueva-Hemandez, P. Cozzone, T. Del Ser, J. Sans-Sabrafen, M. Zappia, P. W. A. Willems, G. Tchernia, D. Gardeur, R. Bauer, F. Palomo, H. Metz, S. Lamoureux, C. Chastang, I. Reinhard, A. Goldfarb, S. Harder, Jordi Río, C. Ozkara, E. Tekinsoy, P. Vontobell, J. De Recondo, M. Rabasa, L. Lacomblez, F. Boon, Dgt Thomas, V. Palma, Renato Mantegazza, A. Dervis, M. Nueckel, B. YalÇinerner, I. Duran, G. Dalla Volta, A. Zubimendi, J. Pinheiro, A. Marbini, Xavier Montalban, H. Wekerle, X. Pereira Monteino, F. Crespo, F. Koskas, N. Battistini, C. Ruiz, H. Offner, J. de Pommery, P. Kanovsky, J. Y. Barnett, J. Pardo, G. Tomei, R. Rene, H. M. Lokhorst, P. Thajeb, H. Bilgin, D. McGehee, R. Fahsold, L. Morgante, Katie Sidle, C. Delwaide, M. N. Diaye, P. H. Rice, A. Creange, C. Sabev, K. Stephan, K. WeilBenborn, G. Magnani, L. Grymonprez, F. Cardellach, M. Kaps, N. G. Meco, F. Vega, V. Bonifati, A. Desomer, M. Baldy-Moulinier, G. Kvale, F. J. Authier, B. Yegen, T. Ho, J. M. Rozet, E. A. Cabanis, L. Bruce, L. Ambrosoli, M. A. Petrella, M. Hernandez, P. Timmings, H. B. van der Worp, F. Mahieux, A. Urbano-Marquez, D. A. Krendel, A. A. Garcia, R. Divari, R. Michalowicz, M. R. Piedmonte, M. Bondavalli, M. Zanca, P. F. Ippel, Onofre Combarros, B. Tavitian, E. Hirsch, I. Anastasopoulos, A. Roses, A. Köhler, P. Vienna, V. Timmerman, P. Sergi, F. Cornelio, A. Di Pasquale, R. Verleger, S. Castellvirel, J. Proano, B. van Moll, F. Rubio, W. Hacke, I. Lavenu, L. Zetta, M. W. Tas, N. Bittmann, M. Bonamini, O. R. Hommes, V. Dousset, N. Afsar, S. Belal, R. R. Myers, J. Goes, Giuseppe Vita, E. Clementi, V. G. Karepov, M. Jueptner, A Vincent, P. Emmrich, Th. Heb, A. Caballo, J. Gallego, T. Mokrusch, C. Perla, L. Gebuhrer, O. Titlbach, Alessandro Prelle, A. Czlonkowska, M. Russo, D. Hadjiev, T. S. Chkhikvishvili, M. Oehlschlager, G. Becker, I. Günther, E. N. Stenager, J. Garcia Agundez, J. Casademont, J. Batlle, S. Podobnik-Sarkanji, C. Alonso-Villaverde, B. Delaguillaume, B. Genc, B. Mazoyer, A. Rodriguez-Al-barino, Ch. Hilger, B. Ferrero, R. Price, W. Grisold, L. Fuhry, D. Oulbani, D. Ewing, A. Petkov, W. Walther, A. Gokyigit, John Newsom-Davis, J. Tayot, D. Seliak, G. Pelliccioni, D. Campagne, K. Kessler, F. Boureau, D. Perani, J. P. N'Guyen, N. Tchalucova, B. A. Antin-Ozerkis, C. Lacroix, B. D. Aronovich, I. H. Jenkins, E. A. dos Reis, M. Hortells, H. M. Meinck, H. Ch. Buschmann, S. C. J. M. Jacobs, T. Wetter, P. Creissard, N. Martinez, J. Weidenfeldl, H. J. Sturenburg, G. Damlacik, V. Gracia, J. C. Turpin, A. Pou-Serradell, J. P. Vincent, T. Gagoshidze, U. Ozkutlu, M. McLeod, K. Siegfried, I. Tchaoussoglou, J. Hildebrand, S. Kowalska, M. C. Picot, G. Galardin, L. Crevits, F. Andreetta, S. Larumbe-Lobalde, G. de la Sierra, J. C. Alvarez-Cermeno, R. J. Seitz, P. L. Oey, L. Ptacek, A. M. J. Paans, A. Wirrwar, A. Schmied, J. Uilchez, H. Tounsi, D. Hipola, V. Avoledo, Y. Hirata, P. Vermersch, T. M. Aisonobe, J. Valls-SoIè, H. Staunton, J. Dichgans, R. Karabudak, I. Dones, G. Porta, E. Janssens, Maria Martinez, J. M. Fernandez-Real, R. Villagra, Y. Yoshino, C. Kabus, K. Schimrigk, I. Girard-Buttaz, F. Piccoli, F. Aichner, P. Zuchegna, S. M. Al Deeb, F. Bono, N. Busquets, A. Jobert, Patrizia Ciscato, M. Martin, L. Polman, S. Darbra, V. Le Cam-Duchez, F. Baldissera, B. Baykan-Kurt, D. Guez, M. Bratoeva, H. Matsui, M. Mila, H. Perron, L. Bjorge, G. Husby, Steven T. DeKosky, D. R. Cornblath, J. M. Gabriel, J. J. Poza, Y. Wu, A. Toscano, R. P. Kleyweg, J. Kuhnen, S. O. Confort-Gouny, A. Barcelo, A. M. Conti, C. Fiol, C. Steichen-Wiehn, J. Rodes, M. Cavenaile, C. Vedeler, M. Drlicek, C. Argentino, M. L. Peris, A. Cervello, A. Z. GinaÏ, S. Yancheva, D. Passingham, S. Aoba, D. L. Lopez, T. Rechlin, K. Sonka, L. Grazzi, V. Folnegovic-Smalc, Maurizio Moggio, S. Rivaud, F. G. I. Jennekens, C. H. Hartard, H. Meierkord, G. Stocklin, M. D. Catala, W. C. McKay, E. Salmon, C. Navarro, I. Pastor, L. Canafoglia, M. De Braekeleer, P. K. Thomas, C. Mocellini, C. Pierre-Jerome, M. C. Dalakas, P. Pollak, M. Levivier, Niall Quinn, G. E. Rivolta, Z. Tunca, H. Zeumer, J. Garcia Tena, St. Guily, P. Gaudray, Johannes Kornhuber, V. Petrunjashev, R. Montesanti, R. J. Abbott, H. Petit, G. Kiteva-Trencevska, F. Carletto, C. Ramo, I. M. Pino, P. Beau, G. F. Mennuni, F. Moschian, F. Meneghini, B. Zdziarska, B. Fontaine, C. Stephens, G. Meco, K. Reiners, G. Badlan, M. Sessa, I. Degaey, S. M. Hassan, C. Albani, F. Caroeller, M. Schroeder, G. Savettieri, A. Novelletto, R. Kurita, P. Oschmann, I. Plaza, M. Oliveres, Simone Spuler, A. Molins, M. Schwab, J. R. Kalden, C. P. Gennaula, Y. Baklan, O. Picard, J. M. Léger, B. Mokri, E. Ghidoni, M. Jacob, D. Deplanque, W. JÄnisch, C. 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Navasa, J. Ballabriga, G. Broggi, T. Gudeva, C. Rose, J. Vion-Dury, J. A. Gastaut, J. Pniewski, Nicola J. Robertson, G. Kohncke, M. Billot, S. Gok, E. Castellli, F. Denktas, P. Bazzi, F. Spinelli, I. F. Moseley, C. D. Mardsen, B. Barbiroli, O. M. Koriech, A. Miller, Hiroaki Yoshikawa, F. X. Borruat, J. Zielasek, P. Le Coz, J. Pascual, A. Drouet, L. T. Giron, F. Schondube, R. Midgard, M. Alizadeh, M. Liguori, Lionel Ginsberg, L. Harms, C. Tilgner, G. Tognoni, F. Molteni, Mar Tintoré, M. Psylla, C. Goulon-Goeau, M. V. Aguilar, Massimo Filippi, K. H. Mauritz, Thomas V. Fernandez, C. Basset, S. Rossi, P. Meneses, B. Jandolo, T. Locatelli, D. Shechtcr, C. Magnani, R. Ferri, Bruno Dubois, J. M. Warier, S. Berges, F. Idiman, M. Schabet, R. R. Diehl, P. D'aurelio, M. Musior, Reinhard Hohlfeld, P. Smeyers, M. Olivé, A. Riva, C. A. Broere, N. Egund, S. Franceschetti, V. Bonavita, Nicola Canal, E. Timmermans, M. Ruiz, S. Barrandon, G. Vasilaski, B. Deweer, L. Galiano, S. F. T. M. de Bruijn, L. Masana, A. Goossens, B. Heye, K. Lauer, Heinz Gregor Wieser, Stephen R. Williams, B. Garavaglia, A. P. Sempere, F. Grigoletto, P. Poindron, R. Lopez-Pajares, I. Leite, T. A. McNell, C. Caucheteur, J. M. Giron, A. D. Collins, P. Freger, J. Sanhez Del Rio, D. A. Harn, K. Lindner, S. S. Scherer, G. Serve, M. Juncadella, X. Estivill, R. Binkhorst, M. Anderson, B. Tekinsoy, C. Sagan, T. Anastopoulos, G. Japaridze, S. Guillou, F. Erminio, Jon Sussman, P. G. Oomes, D. S. Rust, S. Mascheroni, O. Berger, M. Peresson, K. V. Toyka, T. W. Polder, M. Huberman, B. Arpaci, H. Ramtami, I. Martinez, Ph. Violon, P. P. Gazzaniga Pozzill, R. Ruda, P. Auzou, J. Parker, S. P. Morrissey, Jiahong Zhu, F. Rotondi, P. Baron, W. Schmid, P. Doneda, M. Spadaro, M. C. Nargeot, I. Banchs, J.S.P. van den Berg, R. Ferrai, M. Robotti, M. Fredj, Pedro M. Rodríguez Cruz, B. Erne, D. G. Piepgras, M. C. Arne-Bes, J. Escudero, C. Goetz, A. R. Naylor, M. Hallett, O. Abramsky, E. Bonifacio, L. E. Larsson, R. Pellikka, P. Valalentino, D. Guidetti, B. Buchwald, C. H. Lücking, D. Gauvreau, F. Pfaff, A. Ben Younes-Chennoufi, R. Kiefer, R. Massot, K. A. Hossmann, L. Werdelin, P. J. Baxter, U. Ziflo, S. Allaria, C. D. Marsden, M. Cabaret, S. P. Mueller, E. Calabrese, R. Colao, S. I. Bekkelund, M. Yilmaz, O. Oktem-Tanor, R. Gine, M. E. Scheulen, J. Beuuer, A. Melo, Z. Gulay, M. D. Have, C. Frith, D. Liberati, J. Gozlan, P. Rondot, Ch. Brunholzl, M. Pocchiari, J. Pena, L. Moiola, C. Salvadori, A. Cabello, T. Catarci, S. Webb, C. Dettmers, N. A. Gregson, Alexandra Durr, F. Iglesias, U. Knorr, L. Ferrini-Strambi, F. Kruggel, P. Allard, A. Coquerel, P. Genet, F. Vinuels, C. Oberwittler, A. Torbicki, P. Leffers, B. Renault, B. Fauser, C. Ciano, G. Uziel, J. M. Gibson, F. Anaya, C. Derouesné, C. N. Anagnostou, M. Kaido, W. Eickhoff, G. Talerico, M. L. Berthier, A. Capdevila, M. Alons, D. Rezek, E. Wondrusch, U. Kauerz, D. Mateo, M. A. Chornet, Holon, N. Pinsard, I. Doganer, E. Paoino, H. Strenge, C. Diaz, J. R. Brasic, W. Heide, I. Santilli, W. M. Korn, D. Selcuki, M. J. Barrett, D. Krieger, T. Leon, T. Houallah, M. Tournilhac, C. Nos, D. Chavot, F. Barbieri, F. J. Jimenez-Jimenez, J. Muruzabal, K. Poeck, A. Sennlaub, L. M. Iriarte, L. G. Lazzarino, C. Sanz, P. A. Fischer, S. D. Shorvon, R. Hoermann, F. Delecluse, M. Krams, O. Corabianu, F. H. Hochberg, Christopher J. Mathias, B. Debachy, C. M. Poser, L. Delodovici, A. Jimenez-Escrig, F. Baruzzi, F. Godenberg, D. Cucinotta, P. J. Garcia Ruiz, K. Maier-Hauff, P. R. Bar, R. Mezt, R. Jochens, S. Karakaneva, C. Roberti, E. Caballero, Joseph E. Parisi, M. Zamboni, T. Lacasa, B. Baklan, J. C. Gautier, J. A. Martinez-Matos, W. Pollmann, G. Thomas, L. Verze, E. Chleide, R. Alvarez Sala, I. Noel, E. Albuisson, O. Kastrup, S. I. Rapoport, H. J. Braune, H. Lörler, M. Le Merrer, A. Biraben, S. Soler, S. J. Taagholt, U. Meyding-Lamadé, K. Bleasdale-Barr, Isabella Moroni, Y. Campos, J. Matias-Guiu, G. Edan, M. G. Bousser, John B. Clark, J. Garcia de Yebenes, N. K. Olsen, P. Hitzenberger, S. Einius, Aj Thompson, Ch. J. Vecht, T. Crepin-Leblond, Klaus L. Leenders, A. Di Muzio, L. Georgieva, René Spiegel, K. Sabey, D. Ménégalli, J. Meulstee, U. Liszka, P. Giral, C. Sunol, J. M. Espadaler, A. D. Crockar, K. Varli, G. Giraud, P. J. Hülser, A. Benazzouz, A. Reggio, M. Salvatore, K. Genc, M. Kushnir, S. Barbieri, J. Ph. Azulay, M. Gianelli, N. Bathien, A. AlMemar, F. Hentati, I. Ragueneau, F. Chiarotti, R. C. F. Smits, A. K. Asbury, F. Lacruz, B. Muller, Alan J. Thompson, Gordon Smith, K. Schmidt, C. Daems Monpeun, Juergen Weber, A. Arboix, G. R. Fink, A. M. Cobo, M. Ait Kaci Ahmed, E. Gencheva, Israel-Biet, G. Schlaug, P. De Jonghe, Philip Scheltens, K. Toyka, P. Gonzalez-Porque, A. Cila, J. M. Fernandez, P. Augustin, J. Siclia, S. Medaglini, D. E. Ziogas, A. Feve, L. Kater, G. J. E. Rinkel, D. Leppert, Rüdiger J. Seitz, S. Ried, C. Turc-Carel, G. Smeyers, F. Godinho, M. Czygan, M. Rijntjes, E. Aversa, M. Frigo, Leif Østergaard, J. L. Munoz Blanco, A. Cruz-Matinez, J. De Reuck, C. Theillet, T. Barroso, V. Oikonen, Florence Lebert, M. Kilinc, C. Cordon-Cardon, G. Stoll, E. Thiery, F. Pulcinelli, J. Solski, M. Schmiegelow, L. J. Polman, P. Fernandez-Calle, C. Wikkelso, M. Ben Hamida, M. Laska, E. Kott, W. Sulkowski, C. Lucas, N. M. Bornstein, D. Schmitz, M. W. Lammers, A. de Louw, R. J. S. Wise, P. A. van Darn, C. Antozzi, P. Villanueva, P. H. E. Hilkens, C. Constantin, W. Ricart, A. Wolf, M. Gamba, P. Maguire, Alessandro Padovani, B. M. Patten, Marie Sarazin, H. Ackermann, L. Durelli, S. Timsit, Sebastian Jander, B. W. Scheithauer, G. Demir, J. P. Neau, P. Barbanti, A. Brand, N. AraÇ, V. Fischer-Gagnepain, R. Marchioli, G. Serratrice, C. Maugard-Louboutin, G. T. Spencer, D. Lücke, G. Mainardi, K. Harmant Van Rijckevorsel, G. B. Creel, R. Manzanares, Francesco Fortunato, A. May, J. Workman, K. Johkura, E. Fernandez, Carlo Colosimo, L. Calliauw, L. Bet, Félix F. Cruz-Sánchez, M. Dhib, H. Meinardi, F. Carrara, J. Kuehnen, C. Peiro, H. Lassmann, K. Skovgaard Olsen, A. McDonald, L. Sciulli, A. Cobo, A. Monticelli, B. Conrad, J. Bagunya, J. Benitez, V. Desnizza, B. Dupont, O. Delrieu, D. Moraes, J. J. Heimans, F. Garcia Rio, M. Matsumto, A. Fernandez, R. Nermni, R. Chalmers, M. J. Marchau, F. Aguado, P. Velupillai, P. J. Martin, P. Tassan, V. Demarin, A. Engelien, T. Gerriets, Comar, J. L. Carrasco, J. P. Pruvo, A. Lopez de Munain, D. Pavitt, J. Alarcon, Chris H. Polman, B. Guldin, N. Yeni, Hartmut Brückmann, N. Wilczak, H. Szwed, R. Causaran, G. Kyriazis, M. E. Westarp, M. Gasparini, N. Pecora, J. M. Roda, E. Lang, V. Scaioli, David R. Fish, D. Caputo, O. Gratzl, R. Mercelis, A. Perretti, G. Steimetz, I. Link, C. Rigoletto, A. Catafau, G. Lucotte, M. Buti, G. Fagiolari, A. Piqueras, C. Godinot, J. C. Meurice, Erodriguez J. Dominigo, F. Lionnet, H. Grzelec, David J. Brooks, P. M. G. Munro, F. X. Weilbach, M. Maiwald, W. Split, B. Widjaja-Cramer, V. Ozturk, J. Colas, E. Brizioli, J. Calleja, L. Publio, M. Desi, R. Soffietti, P. Cortinovis-Tourniaire, E. F. Gonano, G. Cavaletti, S. Uselli, K. Westerlind, H. Betuel, C. O. Dhiver, H. Guggenheim, M. Hamon, R. Fazio, P. Lehikoinen, A. Esser, B. Sadzot, G. Fink, Angelo Antonini, D. Bendahan, V. Di Carlo, G. Galardi, A. F. Boller, M. Aksenova, Del Fiore, V. de la Sayette, H. Chabriat, A. Nicoletti, A. Dilouya, M. L. Harpin, E. Rouillet, J. Stam, A. Wolters, M. R. Delgado, Eduardo Tolosa, G. Said, A. J. Lees, L. Rinaldi, A. Schulze-Bonhage, MA Ron, C. Lefebvre, E. W. Radü, R. Alvarez, M. L. Bots, P. Reganati, S. Palazzi, A. Poggi, N. J. Scolding, V. Sazdovitch, T. Moreau, E. Maes, M. A. Estelies, P. Petkova, Jose-Felix Marti-Masso, G De La Meilleure, N. Mullatti, M. Rodegher, N. C. Notermans, T. A. T. Warner, S. Aktan, J. P. Louboutin, L. Volpe, C. Scheidt, W. Aust, C. M. Wiles, U. Schneider, S. K. Braekken, W. R. Willems, K. Usuku, Peter M. Rothwell, C. Talamon, M. L. Sacchetti, A. Codina, M. H. Marion, A. Santoro, J. Roda, A. Bordoni, D. J. Taylor, S. Ertas, H. H. Emmen, J. Vichez, V. BesanÇon, R. E. Passingham, M. L. Malosio, A. Vérier, M. Bamberg, A. W. Hansen, E. Mostacero, G. Gaudriault, Marie Vidailhet, B. Birebent, K. Strijckmans, F. Giannini, T. Kammer, I. Araujo, J. Nowicki, E. Nikolov, A. Hutzelmann, R. Gherardi, J. Verroust, L. Austoni, A. Scheller, A. Vazquez, S. Matheron, H. Holthausen, J. M. Gerard, M. Bataillard, S. Dethy, V. H. Patterson, V. Ivanez, N. P. Hirsch, F. Ozer, M. Sutter, C. Jacomet, M. Mora, Bruno Colombo, A. Sarropoulos, T. H. Papapetropoulos, M. Schwarz, D. S. Dinner, N. Acarin, B. Iandolo, J. O. Riis, P. R. J. Barnes, F. Taroni, J. Kazenwadel, L. Torre, A. Lugaresi, I. L. Henriques, S. Pauli, S. Alfonso, Pedro Quesada, A. S. T. Planting, J. M. Castilla, Thomas Gasser, M. Van der Linden, A. Alfaro, E. Nobile-Orazio, G. Popova, W. Vaalburg, F. G. A. van der Mech, L. Williams, F. Medina, J. P. Vernant, J. Yaouanq, B. Storch-Hagenlocher, A. Potemkowski, R. Riva, M. H. Mahagne, M. Ozturk, Ve. Drory, N. Konic, C. Jungreis, A. Pou Serradell, J. L. Gauvrit, G. J. Chelune, S. Hermandez, T. Dingus, L. Hewer, Ch. Koch, M. N. Metz-Lutz, G. Parlato, M. Sinaki, Charles Pierrot-Deseilligny, H. C. Diener, J. Broeckx, J. Weill-Fulazza, M. L. Villar, M. Rizzo, O. Ganslandt, C. Duran, N. A. Fletcher, G. Di Giovacchino, Susan T. Iannaccone, C. Kolig, N. Fabre, H. A. Crockard, Rita Bella, M. Tazir, E. Papagiannuli, K. Overgaard, Emma Ciafaloni, I. Lorenzetti, F. Viader, P. A. H. Millac, I. Montiel, L. H. Visser, M. Palomar, P. L. Murgia, H. Pedersen, Rafael Blesa, S. Seddigh, W. O. Renier, I. Lemahieu, H. M. L. Jansen, L. Rosin, J. Galofre, K. Mattos, M. Pondal, G. M. Hadjigeorgiou, D. Francis, L. Cantin, D. Stegeman, M. Rango, A. B. M. F. Karim, S. Schraff, B. Castellotti, I. Iriarte, E. Laborde, T. J. Tjan, R. Mutani, D. Toni, B. Bergaasco, J. G. Young, C. Klotzsch, A. Zincone, X. Ducrocq, M. Uchuya, O. J. Kolar, A. Quattrone, T. Bauermann, Nereo Bresolin, J. Vallée, B. C. Jacobs, A. Campos, Werner Poewe, J. A. Villanueva, A. W. Kornhuber, A. Malafosse, E. Diez-Tejedor, G. Jungreia, M. J. A. Puchner, A. Komiyama, O. Saribas, V. Volpini, L. Geremia, S. Bressi, A. Nibbio, Timothy E. Bates, T. z. Tzonev, E. Ideman, G. A. Damlacik, G. Martino, G. Crepaldi, T. Martino, Kjell Någren, E. Idiman, D. Samuel, J. M. Perez Trullen, Y. van der Graaf, J. O. Thorell, M. J. M. Dupuis, E. Sieber, R. D'Alessandro, C. Cazzaniga, J. Faiss, A. Tanguy, A. Schick, I. Hoksergen, A. Cardozo, R. Shakarishvili, G. K. Wennlng, J. L. Marti-Vilalta, J. Weissenbach, I. L. Simone, Amalia C. Bruni, Darius J. Adams, C. Weiller, A. Pietrangeli, F. Croria, C. Vigo-Pelfrey, Patricia Limousin, A. Ducros, G. Conti, O. Lindvall, E. Richter, M. Zuffi, A. Nappo, T. Riise, J. Wijdenes, M. J. Fernandez, J. Rosell, P. Vermersh, S. Servidei, M. S. C. Verdugo, F. Gouttiere, W. Solbach, M. Malbezin, I. S. Watanabe, A. Tumac, W. I. McDonald, D. A. Butterfield, P. P. Costa, F. deRino, F. Bamonti, J. M. Cesar, C. H. Lahoz, I. Mosely, M. Starck, M. H. Lemaitre, K. M. Stephan, S. Tex, R. Bokonjic, I. Mollee, L. Pastena, M. Gutierrez, F. Boiler, M. C. Martinez-Para, M. Velicogna, O. Obuz, A. Grinspan, M. Guarino, L. M. Cartier, E. Ruiz, D. Gambi, S. Messina, M. Villa, Michael G. Hanna, J. Valk, Leone Pascual, M. Clanet, Z. Argov, B. Ryniewicz, E. Magni, B. Berlanga, K. S. Wong, C. Gellera, C. Prevost, F. Gonzalez-Huix, R. Petraroli, J. E. G. Benedikz, I. Kojder, C. Bommelaer, L. Perusse, M. R. Bangioanni, Guy M. McKhann, A. Molina, C. Fresquet, E. Sindern, Florence Pasquier, M. J. Rosas, M. Altieri, O. Simoncini, M. Koutroumanidis, C. A. F. Tulleken, M. Dary-Auriol, S. Oueslati, H. Kruyer, I. Nishisho, C. R. Horning, A. Vital, G. V. Czettritz, J. Ph. Neau, B. Mihout, A. Ameri, M. Francis, S. Quasthoff, D. Taussig, S. Blunt, P. Valentin, C. Y. Gao, O. Heinzlef, H. d'Allens, C. Coudero, M. Erfas, G. Borghero, P. J. Modrego Pardo, M. C. Patrosso, N. L. Gershfeld, P. A. J. M. Boon, O. Sabouraud, M. Lara, J. Svennevig, G. L. Lenzi, A. Barrio, H. Villaroya, JosÇ M. Manubens, O. Boespflug-Tanguy, M. Carreras, D. A. Costiga, J. P. Breux, S. Lynn, C. Oliveras Ley, A. G. Herbaut, J. Nos, C. Tornali, Y. A. Hekster, J. L. Chopard, J. M. Manubens, P. Chemouilli, A. Jovicic, F. Dworzak, S. Smirne, S. E. Soudain, B. Gallano, D. Lubach, G. Masullo, G. Izquierdo, A. Pascual Leone Pascual, A. Sessa, V. Freitas, O. Crambes, L. Ouss, G. W. Van Dijk, P. Marchettini, P. Confalonieri, M. Donaghy, A. Munnich, M. Corbo, and M. E. L. van der Burg
Subjects: Neurology, business.industry, Media studies, Library science, Medicine, Neurology (clinical), business
Published: 1994

42. Diagnostische Wertigkeit von 2D- und 3D-FLAIR-Sequenzen in der Schlaganfalldiagnostik

Author: J Hodel, Mathieu Rodallec, and X Leclerc
Published: 2014

43. [Diffusion-weighted MR imaging of the brain]

Author: O, Naggara, L, Létourneau-Guillon, C, Mellerio, M, Belair, J-P, Pruvo, X, Leclerc, J-F, Meder, and C, Oppenheim
Subjects: Diagnosis, Differential, Brain Diseases, Diffusion Magnetic Resonance Imaging, Brain Neoplasms, Brain Abscess, Humans, Image Enhancement, Prognosis, Brain Ischemia
Abstract: Imaging of water diffusion or diffusion-weighted MR imaging provides physiological information about brain diseases that cannot be obtained from conventional sequences. This technique is very sensitive for the detection of cerebral ischemia from arterial origin and can distinguish cerebral ischemia from other non-vascular brain pathologies in patients presenting with abrupt onset of focal neurological deficit. Diffusion-weighted imaging is used for the evaluation of non-vascular diseases as well. Combined with conventional sequences, it is helpful to differentiate brain abscesses from necrotic tumors. Quantitative diffusion-weighted imaging provides additional information in the characterization of tumors or inflammatory, degenerative and metabolic lesions. Finally, diffusion-weighted imaging data also has prognostic value.
Published: 2010

44. Stroke outcome after endovascular treatment: Influence of the site of occlusion

Author: P. Aguettaz, Marie Bodenant, M. Aggour, Didier Leys, Hilde Hénon, and X. Leclerc
Subjects: medicine.medical_specialty, Neurology, business.industry, Occlusion, Stroke outcome, Medicine, Neurology (clinical), Endovascular treatment, business, Surgery
Published: 2013

45. Usefulness of CT Angiography with Volume Rendering After Carotid Angioplasty and Stenting

Author: X. Leclerc, Jean-Yves Gauvrit, and J. P. Pruvo
Subjects: Male, medicine.medical_specialty, Arterial disease, medicine.medical_treatment, Postoperative Complications, Carotid angioplasty, Angioplasty, Image Processing, Computer-Assisted, Humans, Medicine, Carotid Stenosis, Radiology, Nuclear Medicine and imaging, Vascular Patency, Aged, Endarterectomy, Carotid, medicine.diagnostic_test, business.industry, Follow up studies, Volume rendering, General Medicine, Middle Aged, medicine.disease, Thrombosis, Carotid artery.internal, Angiography, Female, Stents, Radiology, Tomography, X-Ray Computed, business, Carotid Artery, Internal, Follow-Up Studies
Published: 2000

46. [Aneurismal subarachnoid hemorrhage in the elderly subject. Should this patient participate in a randomized clinical trial?]

Author: F, Proust, S, Bracard, L, Thines, X, Leclerc, G, Penchet, J, Bergé, J-R, Vignes, B, Irthum, J, Gabrillargues, J, Chazal, B, Bataille, J, Drouinau, K, Mourier, F, Ricolfi, E, Gay, P, Bessou, M, Lonjon, J, Sedat, P, David, P, Lajaunias, X, Morandi, J-Y, Gauvrit, I, Pelissou, F, Turjman, P-H, Roche, H, Dufour, O, Levrier, E, Emery, P, Courthéoux, J, Laguarrigue, C, Cognard, T, Civit, and J-P, Lejeune
Subjects: Aged, 80 and over, Male, Humans, Subarachnoid Hemorrhage, Neurosurgical Procedures, Randomized Controlled Trials as Topic
Published: 2009

47. Spontaneous thrombosis of a recurrent clipped intracranial aneurysm

Author: F. Hassan, Christian Taschner, Jean-Paul Lejeune, J.P. Pruvo, X. Leclerc, and Laurent Thines
Subjects: medicine.medical_specialty, Subarachnoid hemorrhage, medicine.medical_treatment, Remission, Spontaneous, Aneurysm, Recurrence, medicine.artery, Occlusion, Anterior cerebral artery, medicine, Humans, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Embolization, Endovascular treatment, Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Intracranial Aneurysm, Middle Aged, medicine.disease, Embolization, Therapeutic, cardiovascular system, Female, Neurology (clinical), Radiology, Intracranial Thrombosis, business, Spontaneous thrombosis, Cerebral angiography
Abstract: Spontaneous thrombosis of an intracranial aneurysm is a rare event. It is predominantly observed with aneurysms that are large and have relatively narrow necks. We report here a case of a 48-year-old woman presenting with subarachnoid hemorrhage (SAH) due to rupture of a 2-mm aneurysm of the anterior cerebral artery treated by microsurgical clipping. Six months after treatment of the aneurysm, the patient presented with severe headache. SAH was excluded, but computed tomographic angiography (CTA) revealed the recurrence of a large aneurysm (7 mm) that was confirmed by cerebral angiography (DSA). Endovascular treatment was scheduled for several days later, but DSA also revealed spontaneous occlusion of the recurrent aneurysm. On the control CTA performed one week later, the recurrent aneurysm had again reappeared, again confirmed by DSA, and was subsequently treated by coil embolization.
Published: 2009

48. [Case No. 2. Cerebral lymphoma]

Author: X, Leclerc, S, Caron, C, Laurent, M, Faivre-Pierret, and J P, Pruvo
Subjects: Lymphoma, Brain Neoplasms, Humans, Female, Aged
Published: 2008

49. [Case No. 3. Hemangioblastoma]

Author: X, Leclerc, S, Caron, C, Laurent, M, Faivre-Pierret, and J P, Pruvo
Subjects: Male, Young Adult, Humans, Spinal Cord Neoplasms, Hemangioblastoma
Published: 2008

50. [Case No. 4. Giant perivascular spaces (Virchow Robin)]

Author: X, Leclerc, S, Caron, C, Laurent, M, Faivre-Pierret, and J P, Pruvo
Subjects: Adult, Brain Diseases, Brain, Humans, Female, Dilatation, Pathologic
Published: 2008

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