12 results on '"Wubben R"'
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2. Noordzeevissers verkopen hun vis zelf via internet : VersvandeVisser.nl
- Author
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van Eijk, H., Wubben, R., and Taal, C.
- Subjects
fish ,marine fisheries ,logistics ,handel ,LEI NAT HULPB - Aquatische Hulpbronnen ,logistiek ,vis ,zeevisserij ,markets ,zeevissen ,internet ,marine fishes ,trade ,markten - Abstract
Vissers kunnen via internet, met een eigen ‘webmarket’, een aanzienlijk hogere omzet en een hogere marge per kilogram vis realiseren in vergelijking met de bestaande verkoopmethode via de visafslag. Met deze nieuwe afzetmogelijkheid in de keten voeren de vissers zelf de regie. De directe relatie met de klant die zo wordt gecreëerd, stelt de visser in staat om meer klantgericht te gaan opereren. De in dit rapport kort uitgewerkte businesscase, webmarket “VersvandeVisser.nl”, verschaft Nederlandse Noordzeevissers inzicht 2 in de rollen, kosten en opbrengsten per ketenschakel. Hiermee is inzichtelijk gemaakt waar mogelijkheden voor vissers liggen om zelf binnen de keten een grotere rol te spelen in het vermarkten van duurzaam gevangen vis, waardoor betere opbrengsten kunnen worden gerealiseerd. Door aan te sluiten op een al opgezette webmarkettool, ’VersvandeKweker.nl’, zou in samenwerking met de visafslag in Scheveningen (UFA, United Fish Auctions) en andere partijen, een pilot moeten worden gestart om rechtstreeks (via internet) verse vis en garnalen aan consumenten en zakelijke klanten te verkopen.
- Published
- 2013
3. Excessive retroversion of the glenoid cavity. A cause of non-traumatic posterior instability of the shoulder.
- Author
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Brewer, B J, Wubben, R C, and Carrera, G F
- Published
- 1986
4. Novel resource regulator for media-processing algorithms on programmable components [video processing]
- Author
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Hentschel, C., primary and Wubben, R., additional
- Published
- 2005
- Full Text
- View/download PDF
5. 48.3: LCD Overdrive Frame Memory Reduction using Scalable DCT-based Compression
- Author
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Wubben, R. H. M., primary, Hekstra, G. J., additional, and Schmeitz, H. A. W., additional
- Published
- 2004
- Full Text
- View/download PDF
6. Neutrophils in COVID-19: Not Innocent Bystanders.
- Author
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McKenna E, Wubben R, Isaza-Correa JM, Melo AM, Mhaonaigh AU, Conlon N, O'Donnell JS, Ní Cheallaigh C, Hurley T, Stevenson NJ, Little MA, and Molloy EJ
- Subjects
- Humans, Neutrophils, SARS-CoV-2, Systemic Inflammatory Response Syndrome, COVID-19 complications, Extracellular Traps
- Abstract
Unusually for a viral infection, the immunological phenotype of severe COVID-19 is characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil-to-lymphocyte ratio correlating with disease severity. Neutrophils are the most abundant immune cell in the bloodstream and comprise different subpopulations with pleiotropic actions that are vital for host immunity. Unique neutrophil subpopulations vary in their capacity to mount antimicrobial responses, including NETosis (the generation of neutrophil extracellular traps), degranulation and de novo production of cytokines and chemokines. These processes play a role in antiviral immunity, but may also contribute to the local and systemic tissue damage seen in acute SARS-CoV-2 infection. Neutrophils also contribute to complications of COVID-19 such as thrombosis, acute respiratory distress syndrome and multisystem inflammatory disease in children. In this Progress review, we discuss the anti-viral and pathological roles of neutrophils in SARS-CoV-2 infection, and potential therapeutic strategies for COVID-19 that target neutrophil-mediated inflammatory responses., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 McKenna, Wubben, Isaza-Correa, Melo, Mhaonaigh, Conlon, O’Donnell, Ní Cheallaigh, Hurley, Stevenson, Little and Molloy.)
- Published
- 2022
- Full Text
- View/download PDF
7. Neutrophils: Need for Standardized Nomenclature.
- Author
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McKenna E, Mhaonaigh AU, Wubben R, Dwivedi A, Hurley T, Kelly LA, Stevenson NJ, Little MA, and Molloy EJ
- Subjects
- Humans, Terminology as Topic, Gene Expression Regulation immunology, Myeloid-Derived Suppressor Cells classification, Myeloid-Derived Suppressor Cells immunology, Neutrophils classification, Neutrophils immunology, Secretory Vesicles classification, Secretory Vesicles immunology
- Abstract
Neutrophils are the most abundant innate immune cell with critical anti-microbial functions. Since the discovery of granulocytes at the end of the nineteenth century, the cells have been given many names including phagocytes, polymorphonuclear neutrophils (PMN), granulocytic myeloid derived suppressor cells (G-MDSC), low density neutrophils (LDN) and tumor associated neutrophils (TANS). This lack of standardized nomenclature for neutrophils suggest that biologically distinct populations of neutrophils exist, particularly in disease, when in fact these may simply be a manifestation of the plasticity of the neutrophil as opposed to unique populations. In this review, we profile the surface markers and granule expression of each stage of granulopoiesis to offer insight into how each stage of maturity may be identified. We also highlight the remarkable surface marker expression profiles between the supposed neutrophil populations., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 McKenna, Mhaonaigh, Wubben, Dwivedi, Hurley, Kelly, Stevenson, Little and Molloy.)
- Published
- 2021
- Full Text
- View/download PDF
8. The interplay between the immune system and viruses.
- Author
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Wubben R, Efstathiou C, and Stevenson NJ
- Subjects
- Macrophages, Immunity, Innate, Viruses
- Abstract
The human immune response can be divided into two arms: innate and adaptive immunity. The innate immune system consists of "hard-wired" responses encoded by host germline genes. In contrast, the adaptive response consists of gene elements that are somatically rearranged to assemble antigen-binding molecules with specificity for individual foreign structures. In contrast to the adaptive immune system, which depends upon T and B lymphocytes, innate immune protection is a task performed by cells of both hematopoietic and non-hematopoietic origin. Hematopoietic cells involved in innate immune responses include macrophages, dendritic cells, mast cell, neutrophils, eosinophils, natural killer (NK) cells and natural killer T cells. The induction of an adaptive immune response begins when a pathogen is ingested by an Antigen Presenting Cell (APC), such as the Dendritic cell (DC), in the infected tissue. DCs bridge the gap between first line innate responses and powerful adaptive immune responses, by internalizing, processing and presenting antigens on Major Histocompatibility Complex (MHC) and MHC-like molecules to the adaptive immune cells In addition to DCs, macrophages and B cells are deemed antigen presenting cells (Llewelyn & Cohen, 2002)., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
9. Development and implementation of an emergency medicine graduate training program at Addis Ababa University School of Medicine: challenges and successes.
- Author
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Teklu S, Azazh A, Seyoum N, Woldetsadik A, Tupesis JP, Wubben R, Hunchak C, Meshkat N, Tefera G, and Maskalyk J
- Subjects
- Ethiopia, Humans, Program Development, Education, Medical, Graduate methods, Education, Medical, Graduate organization & administration, Emergency Medicine education, Hospitals, University organization & administration, Hospitals, Urban organization & administration
- Abstract
Background: Ethiopians experience high rates of acute illness and injury that have been sub-optimally addressed by the existing health care system. High rates of patient morbidity and mortality prompted the Federal Ministry of Health (FMOH) and the Addis Ababa University School of Medicine (AAU-SM) to prioritize the establishment of emergency medicine (EM) as a medical specialty in Ethiopia to meet this acute health system need., Objectives: To review the EM residency training program developed and implemented at AAU-SM in partnership with the University of Wisconsin (UW), the University of Toronto (UT) and University of Cape Town (UCT) and to evaluate the progress and challenges to date., Methods: An EM Task Force (EMTF) at AAU-SM developed a context-specific three-year graduate EM curriculum with UW input. This curriculum has been co-implemented by faculty teachers from AAU-SM, UT and UW. The curriculum together with all documents (written, audio, video) are reviewed and used as a resource for this article., Results: Seventeen residents are currently in full-time training. Five residents research projects are finalized and 100% of residents passed their year-end exams., Conclusion: A novel graduate EM training program has been successfully developed and implemented at AAU-SM. Interim results suggest that this curriculum and tri-institutional collaboration has been successful in addressing the emergency health needs of Ethiopians and bolstering the expertise of Ethiopian physicians. This program, at the forefront of EM education in Africa, may serve as an effective model for future EM training development throughout Africa.
- Published
- 2014
10. Emergency medicine and its development in Ethiopia with emphasis on the role of Addis Ababa University, School of Medicine, Emergency Medicine Department.
- Author
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Azazh A, Teklu S, Woldetsadi A, Seyoum N, Geremew H, Busse H, Tefera G, Wubben R, Rankin P, Tupesis JP, Maskalyk J, Landes M, Mehari E, and Derbew M
- Subjects
- Ethiopia, Humans, Emergency Medicine organization & administration, Hospitals, University organization & administration, Hospitals, Urban organization & administration
- Abstract
Introduction: Globally Emergency Medicine (EM) is young discipline and even in developed countries it is about five decades old. In Ethiopia formal pre-hospital care or hospital based Emergency department (ED) development is a recent phenomenon and this article describes development of Emergency Medicine care in Ethiopia before, around and after Ethiopia millennium., Methodology: Documents related to emergency medicine development and implementation from different government and nongovernmental data sources are used as a resource for this article., Results: Emergency Medicine task force (EMTF) has been established in Addis Ababa University (AAU) school of Medicine (SOM) in June 2006 and the taskforce has closely worked with Federal Ministry of Health (FMOH) and Addis Ababa city council Health Bureau (AACCHB). In addition to the main actors many partners have contributed significantly to this initiative. Some of the developments were establishment of emergency departments in Tikur Anbessa Specialized Hospital (TASH) and the restructuring of EM service by FMOH. Emergency care has been considered as a crucial service in hospitals' service along with outpatient and inpatient services. Furthermore, Pre-hospital care initiatives have been commenced in Addis Ababa and expanded to the regions with a arrangement of one or two ambulances to small districts having 100,000 population. There have also been key achievement in human resource development, notably the establishment of EM residency and MSC in EM and critical care nursing. Prehospital care givers training programs in order to produce emergency medicine technicians (EMT) have been started in various regional health professionals training centers. Furthermore, EM module has been included in the current undergraduate medical education. The Ethiopian society of emergency professionals (ESEP) has been established with members from different categories of emergency medicine professionals. In all these developments the emergency medicine training center in the emergency department of AAU has played key role in the training of human resources in different categories., Discussion and Conclusion: The recent successes in EM development is due to concerted efforts of the FMOH, AAU SOM and AACCHB along with committed partners. Hence, it is concluded that consistent local efforts and relevant stakeholders support in EM has resulted in successful development of the field in the country.
- Published
- 2014
11. Aneurysmal bone cyst arising after anterior cruciate ligament rupture.
- Author
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Wubben RC
- Subjects
- Anterior Cruciate Ligament diagnostic imaging, Arthroscopy, Bicycling injuries, Bone Cysts, Aneurysmal diagnostic imaging, Bone Cysts, Aneurysmal pathology, Bone Cysts, Aneurysmal surgery, Child, Follow-Up Studies, Humans, Joint Diseases diagnostic imaging, Joint Diseases etiology, Joint Diseases surgery, Joint Instability diagnostic imaging, Joint Instability etiology, Joint Instability surgery, Male, Radiography, Rupture diagnostic imaging, Rupture surgery, Anterior Cruciate Ligament Injuries, Bone Cysts, Aneurysmal etiology, Knee Joint
- Abstract
An aneurysmal bone cyst, a condition first described in 1942, is a relatively rare benign tumor. Approximately 1% of all primary bone tumors are aneurysmal cysts. Diagnosis is typically made in a patient's first or second decade and rarely follows trauma. This is the first reported case of an aneurysmal bone cyst arising after rupture of the anterior cruciate ligament.
- Published
- 1997
12. Mortality rate of pelvic fracture patients.
- Author
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Wubben RC
- Subjects
- Age Distribution, Fractures, Bone etiology, Humans, Incidence, Wisconsin, Fractures, Bone mortality, Pelvis injuries
- Abstract
The records of 77 consecutive patients admitted to Theda Clark Regional Medical Center in Neenah, Wisconsin with a diagnosis of pelvis fracture over a three year period were reviewed. Data was gathered to determine factors associated with survival to hospital discharge. The series included 41 patients injured in a motor vehicle accident and 34 patients injured in falls. The mortality rate was 9.1% (7/77). Factors found significantly associated with increased mortality included coagulopathy and head injury. The diagnosis of pelvic fracture has a relatively high associated mortality rate (6.4%-30%). The deaths among these patients are not usually a direct result of the fractures themselves but are a result of concomitant injures and complications. The prompt diagnosis of pelvis trauma, associated injuries, and other conditions linked to a high mortality rate can help identify those patients most at risk early in their care. This article attempts to identify specific factors linked to increased mortality. Such clinical information is helpful prognostically as well as in prioritizing patient care.
- Published
- 1996
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