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219 results on '"Wu, Y.W."'

12. Cryo-EM structure of the Cas12m2-crRNA binary complex

Author

Omura, N.S., primary, Nakagawa, R., additional, Wu, Y.W., additional, Sudfeld, C., additional, Warren, V.R., additional, Hirano, H., additional, Kusakizako, T., additional, Kise, Y., additional, Lebbink, H.G.J., additional, Itoh, Y., additional, Oost, V.D.J., additional, and Nureki, O., additional

Published
2023
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20. RADIOMICS BASED ON TWO-DIMENSIONAL AND THREE-DIMENSIONAL ULTRASOUND FOR EXTRATHYROIDAL EXTENSION FEATURE PREDICTION IN PAPILLARY THYROID CARCINOMA

Author

Lu, W.J., Qiu, Y.R., Wu, Y.W., Li, J., Chen, R., Chen, S.N., Lin, Y.Y., OuYang, L.Y., Chen, J.Y., Chen, F., and Qiu, S.D.

Subjects
Endocrinology, Endocrine and Autonomic Systems, Endocrinology, Diabetes and Metabolism, Perspectives
Abstract

AIM: To evaluate the diagnostic performance of radiomics features of two-dimensional (2D) and three-dimensional (3D) ultrasound (US) in predicting extrathyroidal extension (ETE) status in papillary thyroid carcinoma (PTC). PATIENTS AND METHODS: 2D and 3D thyroid ultrasound images of 72 PTC patients confirmed by pathology were retrospectively analyzed. The patients were assigned to ETE and non-ETE. The regions of interest (ROIs) were obtained manually. From these images, a larger number of radiomic features were automatically extracted. Lastly, the diagnostic abilities of the radiomics models and a radiologist were evaluated using receiver operating characteristic (ROC) analysis. We extracted 1693 texture features firstly. RESULTS: The area under the ROC curve (AUC) of the radiologist was 0.65. For 2D US, the mean AUC of the three classifiers separately were: 0.744 for logistic regression (LR), 0.694 for multilayer perceptron (MLP), 0.733 for support vector machines (SVM). For 3D US they were 0.876 for LR, 0.825 for MLP, 0.867 for SVM. The diagnostic efficiency of the radiomics was better than radiologist. The LR model had favorable discriminate performance with higher area under the curve. CONCLUSION: Radiomics based on US image had the potential to preoperatively predict ETE. Radiomics based on 3D US images presented more advantages over radiomics based on 2D US images and radiologist.

Published
2022

47. Aqueous extract of Anoectochilus formosanus attenuate hepatic fibrosis induced by carbon tetrachloride in rats

Author

Shih, C.C., Wu, Y.W., and Lin, W.C.

Subjects
Carbon tetrachloride -- Health aspects, Medicinal plants -- Health aspects, Liver cirrhosis -- Health aspects, Glutathione -- Health aspects, Biological sciences, Health, Science and technology, Health aspects
Abstract

Abstract The aim of this study was to investigate the effects of aqueous extract of Anoectochilus formosanus (AFE) on liver fibrogenesis in carbon tetrachloride (C[Cl.sub.4])-induced cirrhosis. Fibrosis was induced in [...]

Published
2005

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