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23 results on '"Wu, Wendan"'

2. Lithocarpus polystachyus Rehd. ameliorates cerebral ischemia/reperfusion injury through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3-mediated pyroptosis.

Author

Liu, Daifang, Wu, Wendan, Wang, Tingting, Zhan, Guiyu, Zhang, Yuandong, Gao, Jianmei, and Gong, Qihai

Subjects
CEREBRAL infarction, CEREBRAL ischemia, REPERFUSION injury, ISCHEMIC stroke, PROTEIN-protein interactions
Abstract

Introduction: Ischemic stroke (IS) is a serious threat to human life and health, and cerebral ischemia/reperfusion injury (CIRI) exacerbates IS by enhancing neuroinflammation and oxidative stress. Sweet tea (ST) comprises several bioactive components, such as phlorizin, trilobatin, and phloretin, with diverse pharmacological activities. However, it remains uncertain whether ST can confer protection against CIRI. In this study, we aimed to investigate the impact and potential underlying mechanism of ST in the context of CIRI. Methods: CIRI model were established in male sprague dawley (SD) rats. The neurobehavioral assessment, the volume of cerebral infarction and the morphology of neurons were measured to complete the preliminary pharmacodynamic study. The therapeutic targets and pathways of ST on IS were obtained by protein-protein interaction, molecular docking and Metascape database. The predicted results were further verified in vivo. Results: Our results revealed that ST treatment significantly ameliorated brain damage in rats subjected to CIRI by mitigating mitochondrial oxidative stress and neuroinflammation. Additionally, we identified the PI3K/AKT/NF-κB pathway and the NLRP3-mediated pyroptosis axis as crucial processes, with molecular docking suggested direct interactions between the main compounds of ST and NLRP3. Conclusion: ST safeguards against CIRI-induced neuronal loss, neuroinflammation and oxidative stress through the inhibition of the PI3K/AKT/NF-κB pathway and the regulation of NLRP3-mediated pyroptosis. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Additional file 5 of Transcriptomic resources for prairie grass (Bromus catharticus): expressed transcripts, tissue-specific genes, and identification and validation of EST-SSR markers

Author

Sun, Ming, Dong, Zhixiao, Yang, Jian, Wu, Wendan, Zhang, Chenglin, Zhang, Jianbo, Zhao, Junming, Xiong, Yi, Jia, Shangang, and Ma, Xiao

Subjects
fluids and secretions, biochemical phenomena, metabolism, and nutrition
Abstract

Additional file 5: Figure S5. The original and full-length gel images for amplification products of part polymorphic primers pairs on studied accessions. The accessions numbers showed in Table 6 were labeled on each gel image, and the bands surrounded by red frames from ESP-178 and ESP-372 were verified by sequencing the amplified products. The markers were on both sides of each gel image.

Published
2021
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12. Additional file 10 of Transcriptomic resources for prairie grass (Bromus catharticus): expressed transcripts, tissue-specific genes, and identification and validation of EST-SSR markers

Author

Sun, Ming, Dong, Zhixiao, Yang, Jian, Wu, Wendan, Zhang, Chenglin, Zhang, Jianbo, Zhao, Junming, Xiong, Yi, Jia, Shangang, and Ma, Xiao

Abstract

Additional file 10: Table S5. Morphological trait list of B. catharticus : names, abbreviations and measuring methods.

Published
2021
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16. Preparation of polyvinyl alcohol/graphene oxide composites and their adsorption properties

Author

Dong, Yanyan, Lis Arias, Manuel José, Hu, Chengye, Wu, Wendan, Liang, Liping, Mou, Xinlan, Meng, Xu, Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, and Universitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil

Subjects
PVA/GO, Composite material, Enginyeria química [Àrees temàtiques de la UPC], Materials compostos, Polymers, Grafè, Adsorció, Composite materials, Adsorption, Graphene, Polymer, Polímers
Abstract

The polyvinyl alcohol/graphene oxide (PVA/GO) hydrogel was prepared. It was confirmed that the adsorption performance of polyvinyl alcohol/graphene oxide hydrogel composite material was improved, and it does not cause secondary pollution. According to adsorption experiments, it was found that PVA/ GO adsorbent with a content of 30 % graphene oxide has the best comprehensive performance. The suitable environment of adsorption was under 25°C, 12-18 h for adsorption time and acidic conditions. The suitable adsorbent dosage was 0.3g and the suitable concentration of the dye was 10 mg/L The authors gratefully acknowledge the financial support of the Shaoxing Public Welfare Project (Grant No. 2017B70042), and the International Science and Technology Cooperation Project of Shaoxing University (Grant No. 2019LGGH1004)

Published
2020

17. Preparation of polyvinyl alcohol/graphene oxide composites and their adsorption properties

Author

Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil, Dong, Yanyan, Lis Arias, Manuel José, Hu, Chengye, Wu, Wendan, Liang, Liping, Mou, Xinlan, Meng, Xu, Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil, Dong, Yanyan, Lis Arias, Manuel José, Hu, Chengye, Wu, Wendan, Liang, Liping, Mou, Xinlan, and Meng, Xu

Abstract

The polyvinyl alcohol/graphene oxide (PVA/GO) hydrogel was prepared. It was confirmed that the adsorption performance of polyvinyl alcohol/graphene oxide hydrogel composite material was improved, and it does not cause secondary pollution. According to adsorption experiments, it was found that PVA/ GO adsorbent with a content of 30 % graphene oxide has the best comprehensive performance. The suitable environment of adsorption was under 25°C, 12-18 h for adsorption time and acidic conditions. The suitable adsorbent dosage was 0.3g and the suitable concentration of the dye was 10 mg/L, The authors gratefully acknowledge the financial support of the Shaoxing Public Welfare Project (Grant No. 2017B70042), and the International Science and Technology Cooperation Project of Shaoxing University (Grant No. 2019LGGH1004), Postprint (published version)

Published
2020

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