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34 results on '"Wu, Weixia"'

2. A Case of Senile Langerhans Cell Histiocytosis with Soft Tissue Mass as the Main Manifestation

Author

XING Mingquan, WU Weixia, SUN Xiaoxing, WANG Qikai, HAN Hao, and GE Hongfeng

Subjects
langerhans cell histiocytosis, soft tissue mass, rare diseases, Medicine
Abstract

Langerhans cell histiocytosis (LCH) is a rare disease characterized by the proliferation of Langerhans cells and the destruction of local tissue. LCH large occurs in children, whilst incidence of the elderly population is extremely low, and there are few related studies. LCH lesions can involve multiple organs and systems, including bone tissue, lymph nodes, skin, liver, and spleen. However, it is rare that multiple soft tissues are implicated for eldly patients with LCH and present with soft tissue mass as the main manifestation. Here is a report on the clinical features, treatment and prognosis of an elderly LCH with multiple soft tissue masses as the main manifestation, in order to provide clinical reference.

Published
2023
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3. Clinical analysis and literature review: a case of Kawasaki disease shock syndrome complicated with heart failure

Author

Wang Jin, Wu Weixia, Yang Yinan, Zhao Liangtao, Min Li, Meng Huitao, and Dong Xiangyu

Subjects
kawasaki disease, kawasaki disease shock syndrome, case report, heart failure, Medicine, Biotechnology, TP248.13-248.65
Abstract

Objective To investigate the clinical and pathological characteristics of KDSS with heart failure. Methods The clinical data of a child with KDSS complicated with heart failure were analyzed, and the related literature was reviewed. Results KDSS is uncommon in Kawasaki disease, and it always attended with serious performance, which can lead to circulatory failure in the acute stage. manifested as systemic circulatory failure with tachycardia, prolonged capillary filling time, chills at the end of limbs, weak pulse, reduced urine volume or disturbance of consciousness. Early identification and timely comprehensive treatment of human immunoglobulin and hormones can significantly improve the condition of shock. Conclusion KDSS is a rare but serious clinical manifestation of Kawasaki disease, and it is easy to be complicated with heart failure. Early identification and comprehensive clinical treatment are effective measures to reduce KDSS complicated with heart failure.

Published
2023
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7. Study on Preparation of Counter Electrodes for Trans-flexible Dye-Sensitized Solar Cells

Author

Wen, Jinyue, Sun, Zhicheng, Li, Furong, Zhang, Qingqing, Wu, Weixia, Liu, Ruping, Ma, Xuan, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Zhao, Pengfei, editor, Ye, Zhuangzhi, editor, Xu, Min, editor, Yang, Li, editor, Zhang, Linghao, editor, and Zhu, Rengao, editor

Published
2021
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12. Gene Expression Profiling of the Liver and Lung in Mice After Exposure to ZnO Quantum Dots

Author

Yang, Yanjie, Li, Peisen, Lin, Yao, Li, Ziqi, Cui, Tianyi, Song, Zhenhua, Wu, Weixia, Lv, Shuangyu, and Ji, Shaoping

Subjects
Male, differentially expressed genes, Sequence Analysis, RNA, Gene Expression Profiling, Ubiquitin-Protein Ligases, Nuclear Proteins, Real-Time Polymerase Chain Reaction, Neoplasm Proteins, Mice, Gene Ontology, ZnO QDs, Liver, International Journal of Nanomedicine, Quantum Dots, Toxicity Tests, Animals, Zinc Oxide, transcriptome, Original Research
Abstract

Yanjie Yang, Peisen Li, Yao Lin, Ziqi Li, Tianyi Cui, Zhenhua Song, Weixia Wu, Shuangyu Lv, Shaoping Ji Henan Provincial Engineering Centre for Tumor Molecular Medicine, Institute of Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, People’s Republic of ChinaCorrespondence: Shuangyu Lv; Shaoping JiSchool of Basic Medical Sciences, Henan University, Kaifeng 475004, People’s Republic of ChinaTel/Fax +86 371 2388 0585Email shuangyulv@henu.edu.cn; shaopingji@henu.edu.cnIntroduction: ZnO quantum dots (QDs) have drawn much attention recently as they are Cd-free, low-cost, and have excellent optical properties. With the expanded production and application of ZnO nanoparticles, concerns about their potential toxicity have also been raised.Materials andMethods: We used RNA sequencing (RNA-seq) to analyze the global gene expression of liver and lung tissues after ZnO QDs treatment. Differentially expressed genes (DEGs) were screened, with a fold change > 1.5 and padj < 0.05. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed, and padj < 0.05 was considered significantly enriched. The RNA-seq results were validated by quantitative real-time polymerase chain reaction (qRT-PCR).Results: A total of 47 and 218 genes were significantly differentially expressed in the liver and lung. Eight GO terms were enriched in the liver and lung, and retinol metabolism and the peroxisome proliferator-activated receptor (PPAR) signaling pathway were shared in different tissues.Discussion: According to DEGs and pathway enrichment analyses, inflammation might be induced in liver and lung tissues after intravenous injection of ZnO QDs. These findings will be helpful for future research and application of ZnO QDs.Keywords: ZnO QDs, transcriptome, differentially expressed genes

Published
2020

13. Additional file 1 of Global research trends and foci of artificial intelligence-based tumor pathology: a scientometric study

Author

Shen, Zefeng, Hu, Jintao, Wu, Haiyang, Chen, Zeshi, Wu, Weixia, Lin, Junyi, Xu, Zixin, Kong, Jianqiu, and Lin, Tianxin

Abstract

Additional file 1: Figure S1 The institutional cooperation map created with Citespace. Figure S2 The overlay visualization map of institution co-authorship analysis generated by VOSviewer. Table S1 The options and settings of VOSviewer for AI-based tumor pathology study. Table S2 The top 20 commonly investigated cancers/tumors in the field of AI-based tumor pathology based on the frequency of author keywords co-occurrence.

Published
2022
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17. Gene Expression Profiling of the Liver and Lung in Mice After Exposure to ZnO Quantum Dots

Author

Yang,Yanjie, Li,Peisen, Lin,Yao, Li,Ziqi, Cui,Tianyi, Song,Zhenhua, Wu,Weixia, Lv,Shuangyu, Ji,Shaoping, Yang,Yanjie, Li,Peisen, Lin,Yao, Li,Ziqi, Cui,Tianyi, Song,Zhenhua, Wu,Weixia, Lv,Shuangyu, and Ji,Shaoping

Abstract

Yanjie Yang, Peisen Li, Yao Lin, Ziqi Li, Tianyi Cui, Zhenhua Song, Weixia Wu, Shuangyu Lv, Shaoping Ji Henan Provincial Engineering Centre for Tumor Molecular Medicine, Institute of Molecular Medicine, School of Basic Medical Sciences, Henan University, Kaifeng 475004, People’s Republic of ChinaCorrespondence: Shuangyu Lv; Shaoping JiSchool of Basic Medical Sciences, Henan University, Kaifeng 475004, People’s Republic of ChinaTel/Fax +86 371 2388 0585Email shuangyulv@henu.edu.cn; shaopingji@henu.edu.cnIntroduction: ZnO quantum dots (QDs) have drawn much attention recently as they are Cd-free, low-cost, and have excellent optical properties. With the expanded production and application of ZnO nanoparticles, concerns about their potential toxicity have also been raised.Materials and Methods: We used RNA sequencing (RNA-seq) to analyze the global gene expression of liver and lung tissues after ZnO QDs treatment. Differentially expressed genes (DEGs) were screened, with a fold change > 1.5 and padj < 0.05. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed, and padj < 0.05 was considered significantly enriched. The RNA-seq results were validated by quantitative real-time polymerase chain reaction (qRT-PCR).Results: A total of 47 and 218 genes were significantly differentially expressed in the liver and lung. Eight GO terms were enriched in the liver and lung, and retinol metabolism and the peroxisome proliferator-activated receptor (PPAR) signaling pathway were shared in different tissues.Discussion: According to DEGs and pathway enrichment analyses, inflammation might be induced in liver and lung tissues after intravenous injection of ZnO QDs. These findings will be helpful for future research and application of ZnO QDs.Keywords: ZnO QDs, transcriptome, differentially expressed genes

Published
2020

20. LINC00565 promotes proliferation and inhibits apoptosis of gastric cancer by targeting miR-665/AKT3 axis

Author

Hu, Jianghong, Ni, Guohua, Mao, Ling, Xue, Xianglong, Zhang, Jijie, Wu, Weixia, Zhang, Shaoru, Zhao, Hong, Ding, Lifang, and Wang, Lihui

Subjects
GC, MicroRNA-665, AKT3, proliferation, LINC00565, CeRNA, apoptosis, OncoTargets and Therapy, Original Research
Abstract

Jianghong Hu,1,* Guohua Ni,2,*Ling Mao,2 Xianglong Xue,1 Jijie Zhang,2 Weixia Wu,2 Shaoru Zhang,3 Hong Zhao,3 Lifang Ding,2 Lihui Wang3 1Department of Gastroenterology, Danyang People’s Hospital of Jiangsu Province and Danyang Hospital Affiliated to Nantong University, Danyang, Jiangsu 212300, People’s Republic of China; 2Department of Oncology, Danyang People’s Hospital of Jiangsu Province and Danyang Hospital Affiliated to Nantong University, Danyang, Jiangsu 212300, People’s Republic of China; 3Central Laboratory, Danyang People’s Hospital of Jiangsu Province and Danyang Hospital Affiliated to Nantong University, Danyang, Jiangsu 212300, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Zhao; Lihui WangDanyang People’s Hospital of Jiangsu Province, 2 Xinmin West Road, Danyang 212300, People’s Republic of ChinaTel +86 511 8658 0096Fax +86 511 8655 3198Email zhjszj@163.com; njuwanglihui@163.comBackground: Numerous studies have shown that long noncoding RNA (lncRNA) is involved in gastric cancer (GC). A relevant microarray containing gastric cancer-related lncRNAs was downloaded from The Cancer Genome Atlas database.Methods: qRT-PCR was used to analyze LINC00565 and AKT3 expression in tumor tissues and cell lines. Proliferative, colony formation and apoptotic abilities of GC cells after transfection of sh-LINC00565 were determined by CCK-8, colony formation assay and flow cytometry, respectively. RIP was enrolled to detect the interaction between LINC00565, AKT3 and miR-665. Dual luciferase assay was used to confirm the relation between miR-665 and LINC00565 and AKT3.Results: Expression level of LINC00565 in GC tissue was highly expressed in GC, which was negatively correlated to prognosis of GC patients. The results showed that knockdown of LINC00565 decreased proliferative and colony formation abilities, and induced apoptosis of GC cells. Pearson analysis showed that LINC00565 was positively correlated with AKT3. Besides, AKT3 was significantly up-regulated in GC. In addition, knockdown of LINC00565 down-regulated AKT3. In order to explore the mechanism, we found that miR-665 could bind to LINC00565 by bioinformatics. Dual-luciferase reporter gene assay and RIP assay both verified the binding relationship between miR-665 and AKT3. Finally, rescue experiments were carried out to explore whether AKT3 could reverse the anti-cancer effect of low-level LINC00565 on GC development.Conclusion: In summary, the expression of LINC00565 is upregulated in GC. LINC00565 can be used as the sponge of miR-665 to up-regulate the expression of AKT3, thus promoting the progression of GC.Keywords: CeRNA, GC, LINC00565, MicroRNA-665, AKT3, proliferation, apoptosis

Published
2019

21. LINC00565 promotes proliferation and inhibits apoptosis of gastric cancer by targeting miR-665/AKT3 axis

Author

Hu,Jianghong, Ni,Guohua, Mao,Ling, Xue,Xianglong, Zhang,Jijie, Wu,Weixia, Zhang,Shaoru, Zhao,Hong, Ding,Lifang, Wang,Lihui, Hu,Jianghong, Ni,Guohua, Mao,Ling, Xue,Xianglong, Zhang,Jijie, Wu,Weixia, Zhang,Shaoru, Zhao,Hong, Ding,Lifang, and Wang,Lihui

Abstract

Jianghong Hu,1,* Guohua Ni,2,* Ling Mao,2 Xianglong Xue,1 Jijie Zhang,2 Weixia Wu,2 Shaoru Zhang,3 Hong Zhao,3 Lifang Ding,2 Lihui Wang3 1Department of Gastroenterology, Danyang People’s Hospital of Jiangsu Province and Danyang Hospital Affiliated to Nantong University, Danyang, Jiangsu 212300, People’s Republic of China; 2Department of Oncology, Danyang People’s Hospital of Jiangsu Province and Danyang Hospital Affiliated to Nantong University, Danyang, Jiangsu 212300, People’s Republic of China; 3Central Laboratory, Danyang People’s Hospital of Jiangsu Province and Danyang Hospital Affiliated to Nantong University, Danyang, Jiangsu 212300, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Zhao; Lihui WangDanyang People’s Hospital of Jiangsu Province, 2 Xinmin West Road, Danyang 212300, People’s Republic of ChinaTel +86 511 8658 0096Fax +86 511 8655 3198Email zhjszj@163.com; njuwanglihui@163.comBackground: Numerous studies have shown that long noncoding RNA (lncRNA) is involved in gastric cancer (GC). A relevant microarray containing gastric cancer-related lncRNAs was downloaded from The Cancer Genome Atlas database.Methods: qRT-PCR was used to analyze LINC00565 and AKT3 expression in tumor tissues and cell lines. Proliferative, colony formation and apoptotic abilities of GC cells after transfection of sh-LINC00565 were determined by CCK-8, colony formation assay and flow cytometry, respectively. RIP was enrolled to detect the interaction between LINC00565, AKT3 and miR-665. Dual luciferase assay was used to confirm the relation between miR-665 and LINC00565 and AKT3.Results: Expression level of LINC00565 in GC tissue was highly expressed in GC, which was negatively correlated to prognosis of GC patients. The results showed that knockdown of LINC00565 decreased proliferative and colony formation abilities, and induced apoptosis of GC

Published
2019

25. Development of Rapid Curing SiO2Aerogel Composite-Based Quasi-Solid-State Dye-Sensitized Solar Cells through Screen-Printing Technology

Author

Jiao, Shouzheng, Sun, Zhicheng, Wen, Jinyue, Liu, Yuanyuan, Li, Furong, Miao, Qingqing, Wu, Weixia, Li, Luhai, and Zhou, Yang

Abstract

Grätzel’s dye-sensitized solar cells (DSSCs) can readily convert sunlight into electricity, attracting considerable attention of global scientists. The fabrication efficiency of DSSCs was greatly limited by the slow fabrication (∼3.5–24 h) of quasi-solid (QS) electrolytes to date. In this study, novel composites of SiO2aerogel with graphene (GR), multi-walled carbon nanotubes, or polyaniline were proposed in the fabrication of QS-state electrolytes. The morphology of these composites was characterized. The gels with SiO2aerogels as QS electrolytes of DSSCs can be rapidly cured in ∼3 s. Using the screen-printing technology, these QS electrolytes can be readily utilized to construct the QS-DSSC to provide high efficiency and great stability. The photovoltaic parameters and interfacial charge-transfer resistances of the QS-DSSC incorporated with our synthetic composites were investigated in detail. Specifically, the SiO2aerogel composed of GR (SiO2@GR) as a gel can greatly improve the performance of QS-DSSCs up to 8.25%. It is likely that these SiO2aerogel composite electrolytes could provide a rapid curing process in the preparation of QS-state DSSCs, which might be useful to promote the development of DSSCs for future industrialization.

Published
2020
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34. Development of Rapid Curing SiO 2 Aerogel Composite-Based Quasi-Solid-State Dye-Sensitized Solar Cells through Screen-Printing Technology.

Author

Jiao S, Sun Z, Wen J, Liu Y, Li F, Miao Q, Wu W, Li L, and Zhou Y

Abstract

Grätzel's dye-sensitized solar cells (DSSCs) can readily convert sunlight into electricity, attracting considerable attention of global scientists. The fabrication efficiency of DSSCs was greatly limited by the slow fabrication (∼3.5-24 h) of quasi-solid (QS) electrolytes to date. In this study, novel composites of SiO 2 aerogel with graphene (GR), multi-walled carbon nanotubes, or polyaniline were proposed in the fabrication of QS-state electrolytes. The morphology of these composites was characterized. The gels with SiO 2 aerogels as QS electrolytes of DSSCs can be rapidly cured in ∼3 s. Using the screen-printing technology, these QS electrolytes can be readily utilized to construct the QS-DSSC to provide high efficiency and great stability. The photovoltaic parameters and interfacial charge-transfer resistances of the QS-DSSC incorporated with our synthetic composites were investigated in detail. Specifically, the SiO 2 aerogel composed of GR (SiO 2 @GR) as a gel can greatly improve the performance of QS-DSSCs up to 8.25%. It is likely that these SiO 2 aerogel composite electrolytes could provide a rapid curing process in the preparation of QS-state DSSCs, which might be useful to promote the development of DSSCs for future industrialization.

Published
2020
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