169 results on '"Wu, Tianxiao"'
Search Results
2. Binding sites and design strategies for small molecule GLP-1R agonists
3. Discovery of novel indazole derivatives as second-generation TRK inhibitors
4. Discovery of novel 3-(1H-pyrazol-4-yl)-1H-indazole derivatives as potent type II TRK inhibitors against acquired resistance
5. Design, synthesis and biological evaluation of novel indolin-2-one derivatives as potent second-generation TRKs inhibitors
6. Structure-based discovery of 1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea as a potent and selective nanomolar type-II PLK4 inhibitor
7. Identification of novel indole derivatives as highly potent and efficacious LSD1 inhibitors
8. Discovery of quinazoline derivatives CZw-124 as a pan-TRK inhibitor with potent anticancer effects in vitro and in vivo
9. Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer
10. Identification of novel and potent PROTACs targeting FAK for non-small cell lung cancer: Design, synthesis, and biological study
11. Design, synthesis, and evaluation of novel 3-thiophene derivatives as potent fungistatic and fungicidal reagents based on a conformational restriction strategy
12. Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold
13. Broadening antifungal spectrum and improving metabolic stablity based on a scaffold strategy: Design, synthesis, and evaluation of novel 4-phenyl-4,5-dihydrooxazole derivatives as potent fungistatic and fungicidal reagents
14. Design, synthesis and evaluation of novel 5-phenylthiophene derivatives as potent fungicidal of Candida albicans and antifungal reagents of fluconazole-resistant fungi
15. Design, synthesis, biological evaluation and pharmacophore model analysis of novel tetrahydropyrrolo[3,4-c]pyrazol derivatives as potential TRKs inhibitors
16. Design, synthesis and biological evaluation of novel benzofuran derivatives as potent LSD1 inhibitors
17. Design, synthesis, biological evaluation and molecular docking study of novel thieno[3,2-d]pyrimidine derivatives as potent FAK inhibitors
18. Synthesis, bioconversion, pharmacokinetic and pharmacodynamic evaluation of N-isopropyl-oxy-carbonyloxymethyl prodrugs of CZh-226, a potent and selective PAK4 inhibitor
19. Discovery of novel 3-(1H-pyrazol-4-yl)-1H-indazole derivatives as potent type II TRK inhibitors against acquired resistance
20. Design, synthesis and biological evaluation of novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potential FAK inhibitors and anticancer agents
21. Scalable, efficient and rapid chemical synthesis of l-Fructose with high purity
22. Design, synthesis, structure-activity relationships study and X-ray crystallography of 3-substituted-indolin-2-one-5-carboxamide derivatives as PAK4 inhibitors
23. Discovery of the First Potent, Selective, and In Vivo Efficacious Polo-like Kinase 4 Proteolysis Targeting Chimera Degrader for the Treatment of TRIM37-Amplified Breast Cancer
24. Discovery of indolin-2-one derivatives as potent PAK4 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study
25. Design, synthesis, and biological evaluation of potent FAK-degrading PROTACs
26. Design, synthesis, and biological evaluation of diaminopyrimidine derivatives as novel focal adhesion kinase inhibitors.
27. Corrigendum: Untargeted metabolomics identified kynurenine as a predictive prognostic biomarker in acute myocardial infarction
28. Discovery of CZS-241: A Potent, Selective, and Orally Available Polo-Like Kinase 4 Inhibitor for the Treatment of Chronic Myeloid Leukemia
29. Design, synthesis and biological evaluation of pyrazolo[3,4-b]pyridine derivatives as TRK inhibitors
30. Spectra-Difference based anomaly-detection for infrared hyperspectral dim-moving-point-target detection
31. Analysis of drought variation characteristics in North China Plain based on optimized remote sensing drought index
32. Analysis of drought variation characteristics in North China Plain based on optimized remote sensing drought index
33. Design, synthesis, and biological evaluation of aminopyridine derivatives as novel tropomyosin receptor kinase inhibitors
34. Untargeted metabolomics identified kynurenine as a predictive prognostic biomarker in acute myocardial infarction
35. Assessment of the Combined Risk of Drought and High-Temperature Heat Wave Events in the North China Plain during Summer
36. Research on monostation passive location technology based on infrared tracking system
37. Design, synthesis, and evaluation of novel 3,4‐isoxazolediamide derivatives for the combination treatment of azole‐resistant candidiasis
38. Quantifying the Effects of Climate Variability, Land-Use Changes, and Human Activities on Drought Based on the SWAT–PDSI Model
39. Micro/nano-structure Co3O4 as high capacity anode materials for lithium-ion batteries and the effect of the void volume on electrochemical performance
40. Tic-tac-toe prediction based on machine learning methods
41. Design, synthesis, and biological evaluation of aminopyridine derivatives as novel tropomyosin receptor kinase inhibitors.
42. Species-Selective Targeting of Fungal Hsp90: Design, Synthesis, and Evaluation of Novel 4,5-Diarylisoxazole Derivatives for the Combination Treatment of Azole-Resistant Candidiasis
43. Structure-Guided Discovery of Novel Indole Derivatives Against LSD1 for Lung Cancer
44. Therapeutic potential of targeting LSD1/ KDM1A in cancers
45. Design, synthesis, and biological evaluation of coumarin analogs as novel LSD1 inhibitors
46. Mixed Noise Estimation Model for Optimized Kernel Minimum Noise Fraction Transformation in Hyperspectral Image Dimensionality Reduction
47. Design, synthesis, and biological evaluation of diaminopyrimidine derivatives as novel focal adhesion kinase inhibitorsElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3md00324h
48. Design, synthesis and biological evaluation of pyrazolo[3,4-b]pyridine derivatives as TRK inhibitorsElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2md00334a
49. Design, synthesis, and biological evaluation of 5‐aminotetrahydroquinoline‐based LSD1 inhibitors acting on Asp375
50. Design, synthesis, and biological evaluation of coumarin analogs as novel LSD1 inhibitors.
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.