1,972 results on '"Wu, T. C."'
Search Results
2. Ultrafast terahertz field control of the emergent magnetic and electronic interactions at oxide interfaces
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Derrico, A. M., Basini, M., Unikandanunni, V., Paudel, J. R., Kareev, M., Terilli, M., Wu, T. -C., Alostaz, A., Klewe, C., Shafer, P., Gloskovskii, A., Schlueter, C., Schneider, C. M., Chakhalian, J., Bonetti, S., and Gray, A. X.
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Condensed Matter - Materials Science ,Condensed Matter - Strongly Correlated Electrons - Abstract
Ultrafast electric-field control of emergent electronic and magnetic states at oxide interfaces offers exciting prospects for the development of new generations of energy-efficient devices. Here, we demonstrate that the electronic structure and emergent ferromagnetic interfacial state in epitaxial LaNiO3/CaMnO3 superlattices can be effectively controlled using intense single-cycle THz electric-field pulses. We employ a combination of polarization-dependent X-ray absorption spectroscopy with magnetic circular dichroism and X-ray resonant magnetic reflectivity to measure a detailed magneto-optical profile and thickness of the ferromagnetic interfacial layer. Then, we use time-resolved and temperature-dependent magneto-optical Kerr effect, along with transient optical reflectivity and transmissivity measurements, to disentangle multiple correlated electronic and magnetic processes driven by ultrafast high-field (~1 MV/cm) THz pulses. These processes include an initial sub-picosecond electronic response, consistent with non-equilibrium Joule heating; a rapid (~270 fs) demagnetization of the ferromagnetic interfacial layer, driven by THz-field-induced nonequilibrium spin-polarized currents; and subsequent multi-picosecond dynamics, possibly indicative of a change in the magnetic state of the superlattice due to the transfer of spin angular momentum to the lattice. Our findings shed light on the intricate interplay of electronic and magnetic phenomena in this strongly correlated material system, suggesting a promising avenue for efficient control of two-dimensional ferromagnetic states at oxide interfaces using ultrafast electric-field pulses.
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- 2024
3. Molecular targets and strategies in the development of nucleic acid cancer vaccines: from shared to personalized antigens
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Chi, Wei-Yu, Hu, Yingying, Huang, Hsin-Che, Kuo, Hui-Hsuan, Lin, Shu-Hong, Kuo, Chun-Tien Jimmy, Tao, Julia, Fan, Darrell, Huang, Yi-Min, Wu, Annie A., Hung, Chien-Fu, and Wu, T.-C.
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- 2024
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4. Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine
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Wang, Suyang, Chen, Chao-Cheng, Hu, Ming-Hung, Cheng, Michelle, Tu, Hsin-Fang, Tsai, Ya-Chea, Yang, Jr-Ming, Wu, T. C., Huang, Chuan-Hsiang, and Hung, Chien-Fu
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- 2024
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5. FLT3L-induced virtual memory CD8 T cells engage the immune system against tumors
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Tu, Hsin-Fang, Kung, Yu-Jui, Lim, Ling, Tao, Julia, Hu, Ming-Hung, Cheng, Michelle, Xing, Deyin, Wu, T. C., and Hung, Chien-Fu
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- 2024
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6. Direct experimental evidence of tunable charge transfer at the $LaNiO_{3}/CaMnO_{3}$ ferromagnetic interface
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Paudel, J. R., Terilli, M., Wu, T. -C., Grassi, J. D., Derrico, A. M., Sah, R. K., Kareev, M., Klewe, C., Shafer, P., Gloskovskii, A., Schlueter, C., Strocov, V. N., Chakhalian, J., and Gray, A. X.
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Condensed Matter - Materials Science - Abstract
Interfacial charge transfer in oxide heterostructures gives rise to a rich variety of electronic and magnetic phenomena. Designing heterostructures where one of the thin-film components exhibits a metal-insulator transition opens a promising avenue for controlling such phenomena both statically and dynamically. In this letter, we utilize a combination of depth-resolved soft X-ray standing-wave and hard X-ray photoelectron spectroscopies in conjunction with polarization-dependent X-ray absorption spectroscopy to investigate the effects of the metal-insulator transition in $LaNiO_{3}$ on the electronic and magnetic states at the $LaNiO_{3}/CaMnO_{3}$ interface. We report on a direct observation of the reduced effective valence state of the interfacial Mn cations in the metallic superlattice with an above-critical $LaNiO_{3}$ thickness (6 u.c.) due to the leakage of itinerant Ni 3d $e_{g}$ electrons into the interfacial $CaMnO_{3}$ layer. Conversely, in an insulating superlattice with a below-critical $LaNiO_{3}$ thickness of 2 u.c., a homogeneous effective valence state of Mn is observed throughout the $CaMnO_{3}$ layers due to the blockage of charge transfer across the interface. The ability to switch and tune interfacial charge transfer enables precise control of the emergent ferromagnetic state at the $LaNiO_{3}/CaMnO_{3}$ interface and, thus, has far-reaching consequences on the future strategies for the design of next-generation spintronic devices.
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- 2023
7. Direct experimental evidence of tunable charge transfer at the LaNiO3/CaMnO3 ferromagnetic interface
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Paudel, JR, Terilli, M, Wu, T-C, Grassi, JD, Derrico, AM, Sah, RK, Kareev, M, Wen, F, Klewe, C, Shafer, P, Gloskovskii, A, Schlueter, C, Strocov, VN, Chakhalian, J, and Gray, AX
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Engineering ,Physical Sciences ,Condensed Matter Physics ,Chemical sciences ,Physical sciences - Abstract
Interfacial charge transfer in oxide heterostructures gives rise to a rich variety of electronic and magnetic phenomena. Designing heterostructures where one of the thin-film components exhibits a metal-insulator transition opens a promising avenue for controlling such phenomena both statically and dynamically. In this work, we utilize a combination of depth-resolved soft x-ray standing-wave and hard x-ray photoelectron spectroscopies in conjunction with polarization-dependent x-ray absorption spectroscopy to investigate the effects of the metal-insulator transition in LaNiO3 on the electronic and magnetic states at the LaNiO3/CaMnO3 interface. We report a direct observation of the reduced effective valence state of the interfacial Mn cations in the metallic superlattice with an above-critical LaNiO3 thickness (6 unit cells, u.c.) facilitated by the charge transfer of itinerant Ni3deg electrons into the interfacial CaMnO3 layer. Conversely, in an insulating superlattice with a below-critical LaNiO3 thickness of 2u.c., a homogeneous effective valence state of Mn is observed throughout the CaMnO3 layers due to the blockage of charge transfer across the interface. The ability to switch and tune interfacial charge transfer enables precise control of the emergent ferromagnetic state at the LaNiO3/CaMnO3 interface and, thus, has far-reaching consequences on the future strategies for the design of next-generation spintronic devices.
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- 2023
8. Sidedness and addition of chemotherapy associated with treatment outcomes of regorafenib for metastatic colorectal cancer: a population-wide cohort study
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Wu, T.-C., Liang, Y.-H., Chen, K.-H., and Shao, Y.-Y.
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- 2024
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9. In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy
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Lam, Brandon, Kung, Yu Jui, Lin, John, Tseng, Ssu-Hsueh, Tu, Hsin-Fang, Huang, Claire, Lee, Brandon, Velarde, Esteban, Tsai, Ya Chea, Villasmil, Rafael, Park, Sung Taek, Xing, Deyin, Hung, Chien-Fu, and Wu, T.- C.
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Chemotherapy -- Patient outcomes ,Tumor antigens -- Testing ,Apoptosis -- Health aspects ,Cancer vaccines -- Dosage and administration ,Cancer -- Chemotherapy ,Radiotherapy -- Patient outcomes ,Health care industry - Abstract
Even with the prolific clinical use of next-generation cancer therapeutics, many tumors remain unresponsive or become refractory to therapy, creating a medical need. In cancer, DCs are indispensable for T cell activation, so there is a restriction on cytotoxic T cell immunity if DCs are not present in sufficient numbers in the tumor and draining lymph nodes to take up and present relevant cancer antigens. To address this bottleneck, we developed a therapeutic based on albumin fused with FMS-related tyrosine kinase 3 ligand (Alb-Flt3L) that demonstrated superior pharmacokinetic properties compared with Flt3L, including significantly longer half-life, accumulation in tumors and lymph nodes, and cross-presenting-DC expansion following a single injection. We demonstrated that Alb-Flt3L, in combination with standard-of-care chemotherapy and radiation therapy, serves as an in situ vaccination strategy capable of engendering polyclonal tumor neoantigen- specific immunity spontaneously. In addition, Alb-Flt3L-mediated tumor control synergized with immune checkpoint blockade delivered as anti-PD-L1. The mechanism of action of Alb-Flt3L treatment revealed a dependency on Batf3, type I IFNs, and plasmacytoid DCs. Finally, the ability of Alb-Flt3L to expand human DCs was explored in humanized mice. We observed significant expansion of human cross-presenting-DC subsets, supporting the notion that Alb-Flt3L could be used clinically to modulate human DC populations in future cancer therapeutic regimens., Introduction The ability to engender potent neoantigen- or tumor-associated antigen-specific [CD8.sup.+] cytotoxic T cell immunity is indispensable to the long-term therapeutic efficacy of essentially all cancer treatment strategies. Classical methods [...]
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- 2024
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10. Vaccination Strategies for the Control and Treatment of HPV Infection and HPV-Associated Cancer
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Farmer, Emily, Cheng, Max A., Hung, Chien-Fu, Wu, T.-C., Krämer, Alwin, Series Editor, Lu, Jiade J., Series Editor, Wu, T.-C., editor, Chang, Mei-Hwei, editor, and Jeang, Kuan-Teh, editor
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- 2021
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11. Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice
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Peng, Shiwen, Xing, Deyin, Ferrall, Louise, Tsai, Ya-Chea, Hung, Chien-Fu, and Wu, T.-C.
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- 2022
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12. Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity
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Kung, Yu-Jui, Lam, Brandon, Tseng, Ssu-Hsueh, MacDonald, Alana, Tu, Hsin-Fang, Wang, Suyang, Lin, John, Tsai, Ya Chea, Wu, T. C., and Hung, Chien-Fu
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- 2022
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13. COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection
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Chi, Wei-Yu, Li, Yen-Der, Huang, Hsin-Che, Chan, Timothy En Haw, Chow, Sih-Yao, Su, Jun-Han, Ferrall, Louise, Hung, Chien-Fu, and Wu, T.-C.
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- 2022
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14. Effects of syphilis infection among HIV-1-positive individuals on suppressive antiretroviral therapy
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Chan, Phillip, Tang, Tommy H. C., Kwong, Ruby T. S., Chan, Lawrence, Chan, Helen S. Y., Lam, K. W., Ting, W. M., Yung, S. K., Lam, Emily C. T., Chu, M. Y., Lam, Wilson, Wu, T. C., Li, Patrick, and Lee, M. P.
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- 2022
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15. Correlation Between the Combustion Performance Indices and the Products of Incomplete Combustion (PICs) in a Laboratory Scale Incinerator
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Lin, Chieh, primary, Wu, T. C., additional, and Liu, S. F., additional
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- 2022
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16. Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
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Marchal, A, Cirulli, E, Neveux, I, Bellos, E, Thwaites, R, Schiabor Barrett, K, Zhang, Y, Nemes-Bokun, I, Kalinova, M, Catchpole, A, Tangye, S, Spaan, A, Lack, J, Ghosn, J, Burdet, C, Gorochov, G, Tubach, F, Hausfater, P, Abel, L, Aiuti, A, Al-Muhsen, S, Al-Mulla, F, Amara, A, Anderson, M, Andreakos, E, Arias, A, Arkin, L, Feldman, H, Bastard, P, Belot, A, Biggs, C, Bogunovic, D, Bolze, A, Bondarenko, A, Borghesi, A, Bousfiha, A, Brodin, P, Bryceson, Y, Butte, M, Casanova, J, Casari, G, Christodoulou, J, Cobat, A, Colobran, R, Condino-Neto, A, Constantinescu, S, Cooper, M, Dalgard, C, Desai, M, Drolet, B, Duval, X, El Baghdadi, J, Eloy, P, Espinosa-Padilla, S, Fellay, J, Flores, C, Franco, J, Froidure, A, Gregersen, P, Grimbacher, B, Haerynck, F, Hagin, D, Halwani, R, Hammarstrom, L, Heath, J, Hsieh, E, Husebye, E, Imai, K, Itan, Y, Jouanguy, E, Kaja, E, Karamitros, T, Kisand, K, Ku, C, Lau, Y, Ling, Y, Lucas, C, Maniatis, T, Mansouri, D, Marodi, L, Mentre, F, Meyts, I, Milner, J, Mironska, K, Mogensen, T, Morio, T, Ng, L, Notarangelo, L, Novelli, A, Novelli, G, O'Farrelly, C, Okada, S, Okamoto, K, Ozcelik, T, Pan-Hammarstrom, Q, Pape, J, Perez de Diego, R, Perez-Tur, J, Perlin, D, Pesole, G, Planas, A, Prando, C, Pujol, A, Puel, A, Quintana-Murci, L, Ramaswamy, S, Renia, L, Resnick, I, Rodriguez-Gallego, C, Sancho-Shimizu, V, Sediva, A, Seppanen, M, Shahrooei, M, Shcherbina, A, Slaby, O, Snow, A, Soler-Palacin, P, Soumelis, V, Tancevski, I, Tayoun, A, Temel, S, Thorball, C, Tiberghien, P, Trouillet-Assant, S, Turvey, S, Uddin, K, Uddin, M, van de Beek, D, Vinh, D, von Bernuth, H, Wauters, J, Zatz, M, Zawadzki, P, Zhang, Q, Zhang, S, Bureau, S, Vacher, Y, Gysembergh-Houal, A, Demerville, L, Benleulmi-Chaachoua, A, Abad, S, Abassi, R, Abdellaoui, A, Abdelmalek, A, Abdoul, H, Abergel, H, Abeud, F, Abgrall, S, Abisror, N, Adechian, M, Aderdour, N, Admane, H, Adnet, F, Afritt, S, Agostini, H, Aguilar, C, Agut, S, Aiello, T, Kaci, M, Oufella, H, Ajeenthiravasan, G, Alauzy, V, Alby-Laurent, F, Allard, L, Alyanakian, M, Borrero, B, Amam, S, Amrouche, L, Andronikof, M, Anglicheau, D, Anguel, N, Annane, D, Aounzou, M, Aparicio, C, Aratus, G, Arlet, J, Arzoine, J, Aslangul, E, Assefi, M, Aubry, A, Audiffred, L, Audureau, E, Auger, C, Auregan, J, Awotar, C, Milla, S, Azan, D, Azemar, L, Azzouguen, B, Elrufaai, M, Badsi, A, Bakouboula, P, Balcerowiak, C, Balde, F, Baldivia, E, Bangamingo, E, Baptiste, A, Baran-Marszak, F, Barau, C, Barget, N, Baronnet, F, Barthelemy, R, Baudel, J, Baudry, C, Baudry, E, Beaugerie, L, Belamri, A, Belaube, N, Belilita, R, Bellassen, P, Belmokhtar, R, Beltran, I, Benainous, R, Benallaoua, M, Benamouzig, R, Benbara, A, Benhida, J, Benkhelouf, A, Benlagha, J, Benmostafa, C, Benothmane, S, Bentifraouine, M, Berard, L, Bernier, Q, Berti, E, Bertier, A, Berton, L, Bessis, S, Beurton, A, Bianco, C, Bianquis, C, Bidar, F, Blanche, P, Blayau, C, Bleibtreu, A, Blin, E, Bloch-Queyrat, C, Boissier, M, Bollens, D, Bolzoni, M, Bompard, R, Bonnet, N, Bonnouvrier, J, Botha, S, Boucenna, W, Bouchama, F, Bouchaud, O, Bouchghoul, H, Boudjebla, T, Boudjema, N, Bouffard, C, Bougle, A, Bouguerra, M, Bouras, L, Bourcier, A, Durand, A, Bourrier, A, Bouscarat, F, Bouvry, D, Bouziri, N, Bouzrara, O, Bribier, S, Brugier, D, Brunel, M, Bui, E, Buisson, A, Bukreyeva, I, Bureau, C, Cadranel, J, Cailhol, J, Calin, R, Vega, C, Canavaggio, P, Cancella, M, Cantin, D, Cao, A, Carbillon, L, Carlier, N, Cassard, C, Castor, G, Cauchy, M, Cha, O, Chaigne, B, Challal, S, Champion, K, Chariot, P, Chas, J, Chauveau, S, Chauvin, A, Chauvin, C, Chavarot, N, Chebbout, K, Cherai, M, Cherubini, I, Chevalier, A, Chiarabini, T, Chinet, T, Chocron, R, Choinier, P, Chommeloux, J, Choquet, C, Choupeaux, L, Chousterman, B, Ciocan, D, Clarke, A, Clavere, G, Clavier, F, Clement, K, Clerc, S, Cohen, Y, Cohen, F, Cohen, A, Coilly, A, Colboc, H, Colin, P, Collet, M, Comarmond, C, Combacon, E, Combes, A, Comparon, C, Constantin, J, Cordel, H, Cordier, A, Costantini, A, Chalumeau, N, Couffignal, C, Coupeau, D, Creange, A, Lamarre, Y, Da Silveira, C, Guibal El Kayani, S, De Castro, N, De Rycke, Y, Del Pozo, L, Delannoy, Q, Delay, M, Deleris, R, Delforge, J, Delphine, L, Demare, N, Demeret, S, Demoule, A, Deniau, A, Depret, F, Derolez, S, Derradji, O, Derridj, N, Descamps, V, Deschamps, L, Desconclois, C, Desnos, C, Desongins, K, Dhote, R, Diallo, B, Didier, M, Diemer, M, Diez, S, Djadi-Prat, J, Djamouri Monnory, F, Djebara, S, Djebra, N, Djietcheu, M, Djillali, H, Djouadi, N, Donneger, S, Santos, C, Dournon, N, Dres, M, Droctove, L, Drogrey, M, Dropy, M, Drouet, E, Dubosq, V, Dubreucq, E, Dubus, E, Duchemann, B, Duchenoy, T, Dudoignon, E, Dufau, R, Dumas, F, Duran, C, Duron, E, Durrbach, A, Duvivier, C, Ebstein, N, El Khalifa, J, Elabbadi, A, Elie, C, Ernotte, G, Esling, A, Etienne, M, Eyer, X, Fartoukh, M, Fayali, T, Fermaut, M, Fiorentino, A, Fliss, S, Fournier, M, Fournier, B, Francois, H, Freynet, O, Frigout, Y, Fromont, I, Fuentes, A, Furet, T, Galand, J, Garnier, M, Gaubert, A, Gaudry, S, Gaugain, S, Gauthier, D, Gautier, M, Georgin-Lavialle, S, Geromin, D, Ghalayini, M, Ghaleh, B, Ghezal, M, Gibelin, A, Gimeno, L, Girard, B, Leprieur, B, Gomes, D, Gomes-Pires, E, Gouge, A, Gouja, A, Goulet, H, Goupil, S, De Bouille, J, Gras, J, Greffe, S, Grimaldi, L, Guedeney, P, Guidet, B, Guillo, M, Gulczynski, M, Hadjam, T, Haguenauer, D, Hammal, S, Hammoudi, N, Hanon, O, Harrois, A, Hautem, C, Hekimian, G, Heming, N, Hermine, O, Ho, S, Houllier, M, Huot, B, Huscenot, T, Saied, W, Ikherbane, G, Imarazene, M, Ingiliz, P, Iratni, L, Jaureguiberry, S, Jean-Marc, J, Jeyarajasingham, D, Jouany, P, Jouis, V, Jourdaine, C, Kafif, O, Kallala, R, Katsahian, S, Kelesyan, L, Keo, V, Ketz, F, Khamis, W, Khelili, E, Khellaf, M, Kotokpo Youkou, C, Kounis, I, Kpalma, G, Krause, J, Labbe, V, Lacombe, K, Lacorte, J, Lafont, A, Lafont, E, Lagha, L, Lamhaut, L, Lancelot, A, Landman, C, Lanternier, F, Larcheveque, C, Combe, C, Lassel, L, Laverdant, B, Lavergne, C, Lavillegrand, J, Lazureanu, P, Le Guennec, L, Leberre, L, Leblanc, C, Leboyer, M, Lecomte, F, Lecorre, M, Leenhardt, R, Lefebvre, M, Lefebvre, B, Legendre, P, Leger, A, Legros, L, Legrosse, J, Lehuunghia, S, Lemarec, J, Leporrier-Ext, J, Lesein, M, Lesur, H, Levy, V, Levy, A, Lopes, E, Lopes, A, Lopez, V, Lopinto, J, Lortholary, O, Louadah, B, Loze, B, Lucas, M, Lucasamichi, A, Luong, L, Magazimama-Ext, A, Maingret, D, Mameri, L, Manivet, P, Mansouri, C, Marcault, E, Marey, J, Marin, N, Marois, C, Martin, O, Martineau, L, Martinez-Lopez, C, Martyniuck, P, De Farcy, P, Marzouk, N, Masmoudi, R, Mebazaa, A, Mechai, F, Mecozzi, F, Mediouni, C, Megarbane, B, Meghadecha, M, Mejean, E, Mekinian, A, Abdelhadi, N, Mekni, R, Meliti, T, Lima, B, Meng, P, Merbah, S, Messani, F, Messaoudi, Y, Mewasing, B, Meziane, L, Michelot-Burger, C, Mignot, F, Minka, F, Miyara, M, Moine, P, Molina, J, Montegnies-Boulet, A, Monti, A, Montlahuc, C, Montout, A, Moores, A, Morbieu, C, Mortelette, H, Mouly, S, Muzaffar, R, Nacerddine, C, Nadal, M, Nadif, H, Nassarmadji, K, Natella, P, Ndingamondze, S, Neraal, S, Nguyen, C, N'Guyen, B, Larmurier, I, Nlomenyengue, L, Noel, N, Nunes, H, Omar, E, Ouazene, Z, Ouedraogo, E, Ouelaa, W, Oukhedouma, A, Amara, Y, Oya, H, Oziel, J, Padilla, T, Paillaud, E, Paiva, S, Parfait, B, Parize, P, Parizot, C, Parrot, A, Pavot, A, Peaudecerf, L, Pene, F, Pepin, M, Pernet, J, Pernin, C, Petit, M, Peyrony, O, Pietri, M, Pietri, O, De Chambrun, M, Pinson, M, Pintado, C, Piquard, V, Pires, C, Planquette, B, Poirier, S, Pomel, A, Pons, S, Ponscarme, D, Pourcelot, A, Pourcher, V, Pouvaret, A, Prever, F, Previlon, M, Prevost, M, Provoost, M, Quemeneur, C, Rafat, C, Rami, A, Ranque, B, Raphael, M, Raphalen, J, Rastoin, A, Raux, M, Rebai, A, Reby, M, Regent, A, Regrag, A, Resche-Rigon, M, Ressaire, Q, Richard, C, Richard, M, Robert, M, Rohaut, B, Rolland-Debord, C, Ropers, J, Roque-Afonso, A, Rosso, C, Rousseaux, M, Rousseaux, N, Roux, S, Roux, L, Rouzaud, C, Rozes, A, Rubenstein, E, Sabate, J, Sabet, S, Sacleux, S, Kermanach, N, Saliba, F, Salmon, D, Savale, L, Savary, G, Sberro, R, Scemla, A, Schlemmer, F, Schwartz, M, Sedfi, S, Sefir-Kribel, S, Seksik, P, Sellier, P, Selves, A, Sembach, N, Semerano, L, Senat, M, Sene, D, Serris, A, Sese, L, Sghiouar, N, Sigaux, J, Siguier, M, Silvain, J, Simon, N, Simon, T, Skandri, L, Slimani, M, Snauwaert, A, Sokol, H, Soliman, H, Soltani, N, Soyer, B, Steg, G, Suarez, L, Szwebel, T, Taffame, K, Tandjaoui-Lambiotte, Y, Tantet, C, Tateo, M, Theodose, I, Thiebaud, P, Thomas, C, Tiercelet, K, Tisserand, J, Tomczak, C, Torelino, K, Touam-Ext, F, Toumi, L, Toury, G, Toy-Miou, M, Dinh Thanh Lien, O, Trandinh, A, Treluyer, J, Trinque, B, Truchot, J, Tubiana, S, Tunesi, S, Turpin, M, Turpin, A, Urbina, T, Narvaez, R, Uzunhan, Y, Vaittinadaayar, P, Valent, A, Valentian, M, Valin, N, Vallet, H, Vaz, M, Vazquezibarra, M, Vedie, B, Velly, L, Verstuyft, C, Viallette, C, Vicaut, E, Vignes, D, Vimpere, D, Virlouvet, M, Voiriot, G, Voisot, L, Weiss, E, Weiss, N, Winchenne, A, Yordanov, Y, Zafrani, L, Zaidan, M, Zaidi, W, Zak, C, Zarhrate-Ghoul, A, Zatout, O, Zeino, S, Zeitouni, M, Zemirli, N, Zerah, L, Zia, O, Ziol, M, Zolario, O, Zuber, J, Andrejak, C, Angoulvant, F, Bachelet, D, Bartoli, M, Basmaci, R, Behillil, S, Beluze, M, Benkerrou, D, Bhavsar, K, Bouadma, L, Bouchez, S, Bouscambert, M, Cervantes-Gonzalez, M, Chair, A, Chirouze, C, Coelho, A, Couffin-Cadiergues, S, D'Ortenzio, E, Debray, M, Deconinck, L, Deplanque, D, Descamps, D, Desvallee, M, Diallo, A, Diouf, A, Dorival, C, Dubos, F, Elharrar, B, Enouf, V, Esperou, H, Esposito-Farese, M, Devouge, E, Gault, N, Gaymard, A, Gigante, T, Gilg, M, Guedj, J, Hoctin, A, Hoffmann, I, Houas, I, Hulot, J, Jaafoura, S, Kaguelidou, F, Kali, S, Khalil, A, Khan, C, Laouenan, C, Laribi, S, Le, M, Le Hingrat, Q, Le Mestre, S, Le Nagard, H, Lescure, F, Letrou, S, Levy, Y, Lina, B, Lingas, G, Lucet, J, Malvy, D, Mambert, M, Meziane, A, Mouquet, 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U., Uzunhan Y., Vaittinadaayar P., Valent A., Valentian M., Valin N., Vallet H., Vaz M., Vazquezibarra M. -A., Vedie B., Velly L., Verstuyft C., Viallette C., Vicaut E., Vignes D., Vimpere D., Virlouvet M., Voiriot G., Voisot L., Weiss E., Weiss N., Winchenne A., Yordanov Y., Zafrani L., Zaidan M., Zaidi W., Zak C., Zarhrate-Ghoul A., Zatout O., Zeino S., Zeitouni M., Zemirli N., Zerah L., Zia O., Ziol M., Zolario O., Zuber J., Andrejak C., Angoulvant F., Bachelet D., Bartoli M., Basmaci R., Behillil S., Beluze M., Benkerrou D., Bhavsar K., Bouadma L., Bouchez S., Bouscambert M., Cervantes-Gonzalez M., Chair A., Chirouze C., Coelho A., Couffin-Cadiergues S., d'Ortenzio E., Debray M. -P., Deconinck L., Deplanque D., Descamps D., Desvallee M., Diallo A., Diouf A., Dorival C., Dubos F., Elharrar B., Enouf V., Esperou H., Esposito-Farese M., Devouge E. 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- Abstract
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B∗15:01 allele and asymptomatic SARS-CoV-2 infection in unvaccinated individuals was recently reported, suggesting a contribution of pre-existing T cell-dependent adaptive immunity. We report a lack of association of classical HLA alleles, including HLA-B∗15:01, with pre-omicron asymptomatic SARS-CoV-2 infection in unvaccinated participants in a prospective population-based study in the United States (191 asymptomatic vs. 945 symptomatic COVID-19 cases). Moreover, we found no such association in the international COVID Human Genetic Effort cohort (206 asymptomatic vs. 574 mild or moderate COVID-19 cases and 1,625 severe or critical COVID-19 cases). Finally, in the Human Challenge Characterisation study, the three HLA-B∗15:01 individuals infected with SARS-CoV-2 developed symptoms. As with other acute primary infections studied, no classical HLA alleles favoring an asymptomatic course of SARS-CoV-2 infection were identified.
- Published
- 2024
17. PD-1 blockade synergizes with intratumoral vaccination of a therapeutic HPV protein vaccine and elicits regression of tumor in a preclinical model
- Author
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Peng, Shiwen, Tan, Marietta, Li, Yen-Der, Cheng, Max A., Farmer, Emily, Ferrall, Louise, Gaillard, Stephanie, Roden, Richard B. S., Hung, Chien-Fu, and Wu, T.-C.
- Published
- 2021
- Full Text
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18. A novel pseudovirus‐based mouse model of SARS-CoV-2 infection to test COVID-19 interventions
- Author
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Tseng, Ssu-Hsueh, Lam, Brandon, Kung, Yu Jui, Lin, John, Liu, Li, Tsai, Ya Chea, Ferrall, Louise, Roden, Richard B. S., Wu, T. C., and Hung, Chien-Fu
- Published
- 2021
- Full Text
- View/download PDF
19. Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine
- Author
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Tseng, Ssu-Hsueh, Liu, Li, Peng, Shiwen, Kim, Jinhwi, Ferrall, Louise, Hung, Chien-Fu, and Wu, T. -C.
- Published
- 2021
- Full Text
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20. Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector
- Author
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Peng, Shiwen, primary, Tu, Hsin-Fang, additional, Cheng, Michelle, additional, Hu, Ming-Hung, additional, Tsai, Hua-Ling, additional, Tsai, Ya-Chea, additional, Koenig, Chelsea, additional, Brayton, Cory, additional, Wang, Hao, additional, Chang, Yung-Nien, additional, Arend, Rebecca C., additional, Levinson, Kimberly, additional, Roden, Richard B. S., additional, Wu, T. C., additional, and Hung, Chien-Fu, additional
- Published
- 2023
- Full Text
- View/download PDF
21. Programmed self-assembly of peptide–major histocompatibility complex for antigen-specific immune modulation
- Author
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Mao, Chih-Ping, Peng, Shiwen, Yang, Andrew, He, Liangmei, Tsai, Ya-Chea, Hung, Chien-Fu, and Wu, T.-C.
- Published
- 2018
22. Vaccination Strategies for the Control and Treatment of HPV Infection and HPV-Associated Cancer
- Author
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Farmer, Emily, primary, Cheng, Max A., additional, Hung, Chien-Fu, additional, and Wu, T.-C., additional
- Published
- 2020
- Full Text
- View/download PDF
23. Coronavirus vaccine development: from SARS and MERS to COVID-19
- Author
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Li, Yen-Der, Chi, Wei-Yu, Su, Jun-Han, Ferrall, Louise, Hung, Chien-Fu, and Wu, T.-C.
- Published
- 2020
- Full Text
- View/download PDF
24. Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model
- Author
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Ma, Ying, Yang, Andrew, Peng, Shiwen, Qiu, Jin, Farmer, Emily, Hung, Chien-Fu, and Wu, T.-C.
- Published
- 2017
- Full Text
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25. The current state of therapeutic and T cell-based vaccines against human papillomaviruses
- Author
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Yang, Andrew, Farmer, Emily, Lin, John, Wu, T.-C., and Hung, Chien-Fu
- Published
- 2017
- Full Text
- View/download PDF
26. Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation
- Author
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Yang, Jr-Ming, Bhattacharya, Sayak, West-Foyle, Hoku, Hung, Chien-Fu, Wu, T.-C., Iglesias, Pablo A., and Huang, Chuan-Hsiang
- Published
- 2019
- Full Text
- View/download PDF
27. Uterine MEIS1::NCOA2 Fusion Sarcoma With Lung Metastasis: A Case Report and Review of the Literature.
- Author
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Deyin Xing, Meyer, Christian F., Gross, John M., Argani, Pedram, Chien-Fu Hung, Wu, T.-C., Vang, Russell, Armstrong, Deborah K., and Gaillard, Stéphanie L.
- Published
- 2024
- Full Text
- View/download PDF
28. Supplementary Figure S1 from HLA-DQB1*02–Restricted HPV-16 E7 Peptide–Specific CD4+ T-Cell Immune Responses Correlate with Regression of HPV-16–Associated High-Grade Squamous Intraepithelial Lesions
- Author
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Peng, Shiwen, primary, Trimble, Cornelia, primary, Wu, Lee, primary, Pardoll, Drew, primary, Roden, Richard, primary, Hung, Chien-Fu, primary, and Wu, T.-C., primary
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- 2023
- Full Text
- View/download PDF
29. Figure S1 from Lineage-Specific Alterations in Gynecologic Neoplasms with Choriocarcinomatous Differentiation: Implications for Origin and Therapeutics
- Author
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Xing, Deyin, primary, Zheng, Gang, primary, Pallavajjala, Aparna, primary, Schoolmeester, J. Kenneth, primary, Liu, Yuehua, primary, Haley, Lisa, primary, Hu, Yan, primary, Liu, Li, primary, Logan, Lisa, primary, Lin, Yuan, primary, Pearce, Kathryn E., primary, Sattler, Christopher A., primary, Tsai, Ya Chea, primary, Vang, Russell, primary, Hung, Chien-Fu, primary, Wu, T.-C., primary, and Ronnett, Brigitte M., primary
- Published
- 2023
- Full Text
- View/download PDF
30. Supplementary Figure 1 from Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell–Mediated Tumor Control in the Genital Tract
- Author
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Sun, Yun-Yan, primary, Peng, Shiwen, primary, Han, Liping, primary, Qiu, Jin, primary, Song, Liwen, primary, Tsai, Yachea, primary, Yang, Benjamin, primary, Roden, Richard B.S., primary, Trimble, Cornelia L., primary, Hung, Chien-Fu, primary, and Wu, T.-C., primary
- Published
- 2023
- Full Text
- View/download PDF
31. Supplementary Figure 2 from Gain of HIF-1α under Normoxia in Cancer Mediates Immune Adaptation through the AKT/ERK and VEGFA Axes
- Author
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Lee, Young-Ho, primary, Bae, Hyun Cheol, primary, Noh, Kyung Hee, primary, Song, Kwon-Ho, primary, Ye, Sang-kyu, primary, Mao, Chih-Ping, primary, Lee, Kyung-Mi, primary, Wu, T.-C., primary, and Kim, Tae Woo, primary
- Published
- 2023
- Full Text
- View/download PDF
32. Supplementary Figure 5 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
33. Supplementary Figure 2 from Toll-like Receptor Agonist Imiquimod Facilitates Antigen-Specific CD8+ T-cell Accumulation in the Genital Tract Leading to Tumor Control through IFNγ
- Author
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Soong, Ruey-Shyang, primary, Song, Liwen, primary, Trieu, Janson, primary, Knoff, Jayne, primary, He, Liangmei, primary, Tsai, Ya-Chea, primary, Huh, Warner, primary, Chang, Yung-Nien, primary, Cheng, Wen-Fang, primary, Roden, Richard B.S., primary, Wu, T.-C., primary, Trimble, Cornelia L., primary, and Hung, Chien-Fu, primary
- Published
- 2023
- Full Text
- View/download PDF
34. Supplementary Figure 4 from Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell–Mediated Tumor Control in the Genital Tract
- Author
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Sun, Yun-Yan, primary, Peng, Shiwen, primary, Han, Liping, primary, Qiu, Jin, primary, Song, Liwen, primary, Tsai, Yachea, primary, Yang, Benjamin, primary, Roden, Richard B.S., primary, Trimble, Cornelia L., primary, Hung, Chien-Fu, primary, and Wu, T.-C., primary
- Published
- 2023
- Full Text
- View/download PDF
35. Table S1 from Lineage-Specific Alterations in Gynecologic Neoplasms with Choriocarcinomatous Differentiation: Implications for Origin and Therapeutics
- Author
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Xing, Deyin, primary, Zheng, Gang, primary, Pallavajjala, Aparna, primary, Schoolmeester, J. Kenneth, primary, Liu, Yuehua, primary, Haley, Lisa, primary, Hu, Yan, primary, Liu, Li, primary, Logan, Lisa, primary, Lin, Yuan, primary, Pearce, Kathryn E., primary, Sattler, Christopher A., primary, Tsai, Ya Chea, primary, Vang, Russell, primary, Hung, Chien-Fu, primary, Wu, T.-C., primary, and Ronnett, Brigitte M., primary
- Published
- 2023
- Full Text
- View/download PDF
36. Supplementary Figure Legends from Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell–Mediated Tumor Control in the Genital Tract
- Author
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Sun, Yun-Yan, primary, Peng, Shiwen, primary, Han, Liping, primary, Qiu, Jin, primary, Song, Liwen, primary, Tsai, Yachea, primary, Yang, Benjamin, primary, Roden, Richard B.S., primary, Trimble, Cornelia L., primary, Hung, Chien-Fu, primary, and Wu, T.-C., primary
- Published
- 2023
- Full Text
- View/download PDF
37. Data from Toll-like Receptor Agonist Imiquimod Facilitates Antigen-Specific CD8+ T-cell Accumulation in the Genital Tract Leading to Tumor Control through IFNγ
- Author
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Soong, Ruey-Shyang, primary, Song, Liwen, primary, Trieu, Janson, primary, Knoff, Jayne, primary, He, Liangmei, primary, Tsai, Ya-Chea, primary, Huh, Warner, primary, Chang, Yung-Nien, primary, Cheng, Wen-Fang, primary, Roden, Richard B.S., primary, Wu, T.-C., primary, Trimble, Cornelia L., primary, and Hung, Chien-Fu, primary
- Published
- 2023
- Full Text
- View/download PDF
38. SSupplementary Figure 1 from Toll-like Receptor Agonist Imiquimod Facilitates Antigen-Specific CD8+ T-cell Accumulation in the Genital Tract Leading to Tumor Control through IFNγ
- Author
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Soong, Ruey-Shyang, primary, Song, Liwen, primary, Trieu, Janson, primary, Knoff, Jayne, primary, He, Liangmei, primary, Tsai, Ya-Chea, primary, Huh, Warner, primary, Chang, Yung-Nien, primary, Cheng, Wen-Fang, primary, Roden, Richard B.S., primary, Wu, T.-C., primary, Trimble, Cornelia L., primary, and Hung, Chien-Fu, primary
- Published
- 2023
- Full Text
- View/download PDF
39. Supplementary Figure 1 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
40. Supplementary Figure 3 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
41. Supplementary Figure 4 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
42. Supplementary Figure 3 from Gain of HIF-1α under Normoxia in Cancer Mediates Immune Adaptation through the AKT/ERK and VEGFA Axes
- Author
-
Lee, Young-Ho, primary, Bae, Hyun Cheol, primary, Noh, Kyung Hee, primary, Song, Kwon-Ho, primary, Ye, Sang-kyu, primary, Mao, Chih-Ping, primary, Lee, Kyung-Mi, primary, Wu, T.-C., primary, and Kim, Tae Woo, primary
- Published
- 2023
- Full Text
- View/download PDF
43. Supplementary Data from Lineage-Specific Alterations in Gynecologic Neoplasms with Choriocarcinomatous Differentiation: Implications for Origin and Therapeutics
- Author
-
Xing, Deyin, primary, Zheng, Gang, primary, Pallavajjala, Aparna, primary, Schoolmeester, J. Kenneth, primary, Liu, Yuehua, primary, Haley, Lisa, primary, Hu, Yan, primary, Liu, Li, primary, Logan, Lisa, primary, Lin, Yuan, primary, Pearce, Kathryn E., primary, Sattler, Christopher A., primary, Tsai, Ya Chea, primary, Vang, Russell, primary, Hung, Chien-Fu, primary, Wu, T.-C., primary, and Ronnett, Brigitte M., primary
- Published
- 2023
- Full Text
- View/download PDF
44. Supplementary Figure 7 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
45. Supplementary Figure 6 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
46. Supplementary Figure 9 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
47. Supplementary Figure Legends from Toll-like Receptor Agonist Imiquimod Facilitates Antigen-Specific CD8+ T-cell Accumulation in the Genital Tract Leading to Tumor Control through IFNγ
- Author
-
Soong, Ruey-Shyang, primary, Song, Liwen, primary, Trieu, Janson, primary, Knoff, Jayne, primary, He, Liangmei, primary, Tsai, Ya-Chea, primary, Huh, Warner, primary, Chang, Yung-Nien, primary, Cheng, Wen-Fang, primary, Roden, Richard B.S., primary, Wu, T.-C., primary, Trimble, Cornelia L., primary, and Hung, Chien-Fu, primary
- Published
- 2023
- Full Text
- View/download PDF
48. Supplementary Figure 8 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
49. Supplementary Figure Legend from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- Author
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Wu, Chao-Yi, primary, Yang, Li-Hua, primary, Yang, Huang-Yu, primary, Knoff, Jayne, primary, Peng, Shiwen, primary, Lin, Yi-Hsin, primary, Wang, Chenguang, primary, Alvarez, Ronald D., primary, Pai, Sara I., primary, Roden, Richard B.S., primary, Hung, Chien-Fu, primary, and Wu, T-C, primary
- Published
- 2023
- Full Text
- View/download PDF
50. Supplementary Figure 2 from Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell–Mediated Tumor Control in the Genital Tract
- Author
-
Sun, Yun-Yan, primary, Peng, Shiwen, primary, Han, Liping, primary, Qiu, Jin, primary, Song, Liwen, primary, Tsai, Yachea, primary, Yang, Benjamin, primary, Roden, Richard B.S., primary, Trimble, Cornelia L., primary, Hung, Chien-Fu, primary, and Wu, T.-C., primary
- Published
- 2023
- Full Text
- View/download PDF
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