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Your search keyword '"Wu, Shuqing"' showing total 186 results
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186 results on '"Wu, Shuqing"'

1. A Determination of the Local Gravitational Acceleration for the Tsinghua Tabletop Kibble Balance

Author

Liu, Weibo, Li, Nanjia, Ma, Yongchao, Hu, Ruo, Wu, Shuqing, Zhao, Wei, Huang, Songling, and Li, Shisong

Subjects
Physics - Instrumentation and Detectors
Abstract

The Kibble balance requires a measurement of the local gravitational acceleration, $g$, with a typical relative measurement uncertainty of $10^{-9}$. In this paper, the determination of $g$ for the Tsinghua tabletop Kibble balance is presented. A polynomial fitting method is proposed for blind transfers of the absolute gravitational acceleration using relative gravimeters, showing agreement with the value obtained by the tide correction within a few parts in $10^{9}$. Horizontal and vertical gravity gradients are extracted by mapping the gravity distribution at different heights. The self-attraction effect of major components in the experiment, as well as some time-varying systematic effects, are modeled. The final determination of the gravitational acceleration at the mass position, with an uncertainty of 5.4 $\mu$Gal ($k=2$), is achieved for the Tsinghua tabletop Kibble balance experiment., Comment: 11 figures, submitted to IEEE Trans. Instrum. Meas

Published
2024

8. Review of the pharmacokinetics of nanodrugs

Author

Shao Xiaotong, Shi Changkuo, Wu Shuqing, Wang Fei, and Li Wenliang

Subjects
ndds, pharmacokinetics, adme, pbpk, Technology, Chemical technology, TP1-1185, Physical and theoretical chemistry, QD450-801
Abstract

Nanodrug delivery systems (NDDSs) are a hotspot of new drug delivery systems with great development potential. They provide new approaches to fighting against diseases. NDDSs are specially designed to serve as carriers for the delivery of active pharmaceutical ingredients to their target sites, and their unique physicochemical characteristics allow for prolonged circulation time, improved targeting, and avoidance of drug resistance. Despite remarkable progress achieved in the preparation and efficacy evaluation of NDDSs, the understanding of the in vivo pharmacokinetics of NDDSs is still insufficient. Analysis of NDDSs is far more complicated than that for small molecular drugs; thus, almost all conventional techniques are inadequate for accurate profiling of their pharmacokinetic behaviour in vivo. In this article, we systematically reviewed the absorption, distribution, metabolism, and excretion of NDDSs and summarized the advanced bioanalytic techniques for tracing the in vivo fate of NDDSs. We also reviewed the physiologically based pharmacokinetic model of NDDS, which has been a useful tool in characterizing and predicting the systemic disposition, target exposure, and efficacy/toxicity of various types of drugs when coupled with pharmacodynamic modelling. We hope that this review will be helpful in improving the understanding of NDDS pharmacokinetics and facilitating the development of NDDSs.

Published
2023
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12. Chitosan-based antioxidant films incorporated with root extract of Aralia continentalis Kitagawa for active food packaging applications

Author

Wu Shuqing, Li Guoping, Li Bosheng, and Duan Hongmei

Subjects
aralia continentalis kitagawa root, extract, antioxidant activity, chitosan, composite films, Polymers and polymer manufacture, TP1080-1185
Abstract

Aralia continentalis Kitagawa and ginseng are both perennial herbs of Araliaceae. The study aimed to investigate the composite packaging films with better fresh-keeping ability. The different mass concentrations of Aralia continentalis Kitagawa root extract (ARE) 0.05%, 0.10%, and 0.15% (v/w) were compounded with chitosan (CH) to make composite packaging films. Food-based composite film, its thickness, density, water contact angle (WCA), oxygen barrier properties (OP), solubility, swelling, transparency, water vapor permeability (WVP), and other physical properties, as well as tensile strength (TS), elongation at break (EAB), Young’s modulus (YM), and the mechanical properties were measured, and the oxidation resistance, thermal properties, and biodegradability were also evaluated, and the structure was analyzed by infrared spectroscopy. The results showed that when the ARE content in the film was increased from 0.05 to 0.15 mg·mL−1, high antioxidant capacity of the CH/ARE film was exhibited (the DPPH and ABTS+ free radical scavenging rate was increased), and the thickness, density, swelling degree, solubility, TS, EAB, and YM of the CH/ARE composite film increased, while WCA, OP, WVP, transparency, and biodegradability were slightly reduced. We had noticed that with the increase in the ARE content, the surface microstructure in CH/ARE film changed significantly, indicating the good compatibility between CH and ARE. In summary, as a natural active substance, ARE can be combined with CH to form films, and the packaging film made can effectively improve the performance of the composite film.

Published
2022
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20. One-year direct and indirect costs of ischaemic stroke in China

Author

Lv, Wei, primary, Wang, Anxin, additional, Wang, Qianyi, additional, Wang, Ruimin, additional, Xu, Qin, additional, Wu, Shuqing, additional, Han, Yi, additional, Jiang, Yong, additional, Lin, Jinxi, additional, Jing, Jing, additional, Li, Hao, additional, Wang, Yongjun, additional, and Meng, Xia, additional

Published
2023
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27. Novel common-mode voltage suppression method for indirect matrix converters based on open-active vectors

Author

Wu, Shuqing, Li, Shanhu, Cai, Min, Liu, Xu, and Zhang, Luyu

Abstract

This paper presents a new common-mode voltage (CMV) suppression strategy based on open-active vectors, which reduces the CMV peak value and suppresses the common-mode spikes caused by switching. In addition, the novel open-active vector is characterized, and its common-mode equivalent circuit is established. The new modulation strategy proposes open-active vectors in place of zero voltage vectors, which reduces the peak magnitude of the output CMV by 42.3%. While reducing the CMV, the complex commutation issue of the rectifier stage and the CMV spike issue brought on by the impact of the inverter stage dead zone are both resolved by the new modulation method. The effectiveness of the new strategy is verified by simulation and experimental results.

Published
2024
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36. 用于绝对重力仪的落体旋转评估方法

Author

王艳 Wang Yan, 王启宇 Wang Qiyu, 冯金扬 Feng Jinyang, 要佳敏 Yao Jiamin, 吴书清 Wu Shuqing, and 叶佳声 Ye Jiasheng

Subjects
Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published
2022

37. Staining method for protein analysis by capillary gel electrophoresis

Author

Wu, Shuqing, Lu, Joann J., Wang, Shili, Peck, Kristy L., Li, Guigen, and Liu, Shaorong

Subjects
Protein binding -- Observations, Albumin -- Chemical properties, Gel electrophoresis -- Methods, Chemistry
Abstract

A novel staining method and the associated fluorescent dye were developed for protein analysis by capillary SDS-PAGE. The method strategy is to synthesize a pseudo-SDS dye and use it to replace some of the SDS in SDS-protein complexes so that the protein can be fluorescently detected. The pseudo-SDS dye consists of a long, straight alkyl chain connected to a negative charged fluorescent head and binds to proteins just as SDS. The number of dye molecules incorporated with a protein depends on the dye concentration relative to SDS in the sample solution, since SDS and dye bind to proteins competitively. In this work, we synthesized a series of pseudo-SDS dyes, and tested their performances for capillary SDS-PAGE. FT-16 (a fluorescein molecule linked with a hexadodecyl group) seemed to be the best among all the dyes tested. Although the numbers of dye molecules bound to proteins (and the fluorescence signals from these protein complexes) were maximized in the absence of SDS, high-quality separations were obtained when co-complexes of SDS-protein-dye were formed. The migration time correlates well with protein size even after some of the SDS in the SDS-protein complexes was replaced by the pseudo-SDS dye. Under optimized experimental conditions and using a laser-induced fluorescence detector, limits of detection of as low as 0.13 ng/mL (bovine serum albumin) and dynamic ranges over 5 orders of magnitude in which fluorescence response is proportional to the square root of analyte concentration were obtained. The method and dye were also tested for separations of real-world samples from E. coli.

Published
2007

38. The results of CCM.G-K2.2017 key comparison

Author

WU, Shuqing, FENG, Jinyang, LI, Chunjian, SU, Duowu, WANG, Qiyu, HU, Ruo, HU, Lishuang, XU, Jinyi, JI, Wangxi, Ullrich, Christian, Pálinkás, Kostelecký, Jakub, Bilker-Koivula, Mirjam, Näränen, Jyri, Merlet, Sébastien, Moigne, Nicolas Le, Mizushima, Shigeki, Francis, Olivier, Choi, In-Mook, Kim, Min-Seok, Alotaibi, Homood M., Aljuwayr, Ahmed, Baumann, Henri, Priruenrom, Tasanee, Woradet, Nattanan, KIRBAŞ, Cafer, Coşkun, Ilkcan, Newel, David, WU, Shuqing, FENG, Jinyang, LI, Chunjian, SU, Duowu, WANG, Qiyu, HU, Ruo, HU, Lishuang, XU, Jinyi, JI, Wangxi, Ullrich, Christian, Pálinkás, Kostelecký, Jakub, Bilker-Koivula, Mirjam, Näränen, Jyri, Merlet, Sébastien, Moigne, Nicolas Le, Mizushima, Shigeki, Francis, Olivier, Choi, In-Mook, Kim, Min-Seok, Alotaibi, Homood M., Aljuwayr, Ahmed, Baumann, Henri, Priruenrom, Tasanee, Woradet, Nattanan, KIRBAŞ, Cafer, Coşkun, Ilkcan, and Newel, David

Abstract

The CCM.G-K2.2017 comparison was organised for the purpose of determination of the degree of equivalence of the national standards for free-fall acceleration measurement. The comparison was held in the Changping Campus of National Institute of Metrology China (NIM), from October to November in 2017. This is the first time that such a comparison is organized outside of the Europe continent and establishes a new global comparison sites in China. This comparison is also the largest ever organized with the participation of 13 instruments. We give the list of the participants who actually performed measurements during the comparison, the data (raw absolute gravity measurements and their uncertainties) submitted by the participants as well as the results of the vertical gravity gradient at the comparison sites. The measurement strategy is briefly discussed and the data elaboration is presented. Finally, the results of the data adjustment are presented including the degrees of equivalence (DoE) of the absolute gravimeters and the key comparison reference values (KCRVs). Overall, the measurements of KC instruments are all consistent given the declared uncertainties. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Published
2020

49. The results of CCM.G-K2.2017 key comparison

Author

WU, Shuqing, primary, FENG, Jinyang, additional, LI, Chunjian, additional, SU, Duowu, additional, WANG, Qiyu, additional, HU, Ruo, additional, HU, Lishuang, additional, XU, Jinyi, additional, JI, Wangxi, additional, Ullrich, Christian, additional, Pálinkáš, Vojtech, additional, Kostelecký, Jakub, additional, Bilker-Koivula, Mirjam, additional, Näränen, Jyri, additional, Merlet, Sébastien, additional, Moigne, Nicolas Le, additional, Mizushima, Shigeki, additional, Francis, Olivier, additional, Choi, In-Mook, additional, Kim, Min-Seok, additional, Alotaibi, Homood M, additional, Aljuwayr, Ahmed, additional, Baumann, Henri, additional, Priruenrom, Tasanee, additional, Woradet, Nattanan, additional, KIRBAŞ, Cafer, additional, Coşkun, İlkcan, additional, and Newel, David, additional

Published
2020
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