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244 results on '"Wu, Jeng-Yih"'

3. Second-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial

Author

Wu, Chun-Ying, Lee, Yi-Chia, Tseng, Ping-Huei, Wu, Jeng-Yih, Tai, Chi-Ming, Lee, Ching-Tai, Wang, Wen-Lun, Liou, Jyh-Ming, Jiang, Xiao-Tao, Chen, Chieh-Chang, Luo, Jiing-Chyuan, Bair, Ming-Jong, Chen, Po-Yueh, Chou, Chu-Kuang, Fang, Yu-Jen, Chen, Mei-Jyh, Chen, Chien-Chuan, Lee, Ji-Yuh, Yang, Tsung-Hua, Yu, Chien-Chun, Kuo, Chia-Chi, Chiu, Min-Chin, Chen, Chi-Yi, Shun, Chia-Tung, Hu, Wen-Hao, Tsai, Min-Horn, Hsu, Yao-Chun, Tseng, Cheng-Hao, Chang, Chi-Yang, Lin, Jaw-Town, El-Omar, Emad M, and Wu, Ming-Shiang

Published
2023
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5. Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis

Author

Hong, Tzu-Chan, primary, El-Omar, Emad M, additional, Kuo, Yu-Ting, additional, Wu, Jeng-Yih, additional, Chen, Mei-Jyh, additional, Chen, Chieh-Chang, additional, Fang, Yu-Jen, additional, Leow, Alex Hwong Ruey, additional, Lu, Hong, additional, Lin, Jaw-Town, additional, Tu, Yu-Kang, additional, Yamaoka, Yoshio, additional, Wu, Ming-Shiang, additional, Liou, Jyh-Ming, additional, Hong, Tzu-Chan, additional, Chen, Yi-Chu, additional, and Chang, Yung-Yueh, additional

Published
2023
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6. Long-term changes of gut microbiota, antibiotic resistance, and metabolic parameters after Helicobacter pylori eradication: a multicentre, open-label, randomised trial

Author

Liou, Jyh-Ming, Chen, Chieh-Chang, Chang, Chih-Min, Fang, Yu-Jen, Bair, Ming-Jong, Chen, Po-Yueh, Chang, Chi-Yang, Hsu, Yao-Chun, Chen, Mei-Jyh, Chen, Chien-Chuan, Lee, Ji-Yuh, Yang, Tsung-Hua, Luo, Jiing-Chyuan, Chen, Chi-Yi, Hsu, Wen-Feng, Chen, Yen-Nien, Wu, Jeng-Yih, Lin, Jaw-Town, Lu, Tzu-Pin, Chuang, Eric Y, El-Omar, Emad M, and Wu, Ming-Shiang

Published
2019
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7. Screening for Clinically Significant Nephrolithiasis Based on Simple Health Checkup Clinical and Urine Parameters in Overweight and Obesity Populations: Machine Learning Models and Multi-hospital Study (Preprint)

Author

Chen, Hao-Wei, primary, Lee, Jung-Ting, additional, Wei, Pei-Siou, additional, Chen, Yu-Chen, additional, Wu, Jeng-Yih, additional, Lin, Chia-I, additional, Chou, Yii-Her, additional, Juan, Yung-Shun, additional, Wu, Wen-Jeng, additional, and Kao, Chung-Yao, additional

Published
2023
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8. Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection

Author

Liou, Jyh-Ming, Lee, Yi-Chia, Lin, Jaw-Town, Wu, Chun-Ying, Wu, Jeng-Yih, Chen, Ching-Chow, Lin, Chun-Hung, Fang, Yu-Ren, Bair, Ming-Jong, Luo, Jiing-Chyuan, Wu, Ming-Shiang, Cheng, Tsu-Yao, Tseng, Ping-Huei, Chiu, Han-Mo, Chang, Chun-Chao, Yu, Chien-Chun, Chiu, Min-Chin, Chen, Yen-Nien, Hu, Wen-Hao, Chou, Chu-Kuang, Tai, Chi-Ming, Lee, Ching-Tai, Wang, Wen-Lun, Chang, Wen-Shiung, Chen, Po-Yueh, Lee, Ji-Yuh, Chen, Chieh-Chang, Fang, Yu-Jen, Yang, Tsung-Hua, Chang, Chi-Yang, Chen, Mei-Jyh, Hsu, Yao-Chun, Hsu, Wen-Feng, Shun, Chia-Tung, and El-Omar, Emad M.

Published
2018
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9. EradicatingHelicobacter pylorivia13C-urea breath screening to prevent gastric cancer in indigenous communities: a population-based study and development of a family index-case method

Author

Lei, Wei-Yi, primary, Lee, Jian-Yu, additional, Chuang, Shu-Ling, additional, Bair, Ming-Jong, additional, Chen, Chien-Lin, additional, Wu, Jeng-Yih, additional, Wu, Deng-Chyang, additional, Tien O’Donnell, Felice, additional, Tien, Hui-Wen, additional, Chen, Yi-Ru, additional, Chiang, Tsung-Hsien, additional, Hsu, Yu-Hsin, additional, Hsu, Tsui-Hsia, additional, Hsieh, Pei-Chun, additional, Lin, Li-Ju, additional, Chia, Shu-Li, additional, Wu, Chao-Chun, additional, Subeq, Yi-Maun, additional, Wen, Shu-Hui, additional, Chang, Hsiu-Chun, additional, Lin, Yu-Wen, additional, Sun, Kuo-Ping, additional, Chu, Chia-Hsiang, additional, Wu, Ming-Shiang, additional, Graham, David Y, additional, Chen, Hsiu-Hsi, additional, and Lee, Yi-Chia, additional

Published
2023
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12. Concomitant, bismuth quadruple, and 14-day triple therapy in the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial

Author

Liou, Jyh-Ming, Fang, Yu-Jen, Chen, Chieh-Chang, Bair, Ming-Jong, Chang, Chi-Yang, Lee, Yi-Chia, Chen, Mei-Jyh, Chen, Chien-Chuan, Tseng, Cheng-Hao, Hsu, Yao-Chun, Lee, Ji-Yuh, Yang, Tsung-Hua, Luo, Jiing-Chyuan, Chang, Chun-Chao, Chen, Chi-Yi, Chen, Po-Yueh, Shun, Chia-Tung, Hsu, Wen-Feng, Hu, Wen-Hao, Chen, Yen-Nien, Sheu, Bor-Shyang, Lin, Jaw-Town, Wu, Jeng-Yih, El-Omar, Emad M, and Wu, Ming-Shiang

Published
2016
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16. Second-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial

Author

Liou, Jyh-Ming, primary, Jiang, Xiao-Tao, additional, Chen, Chieh-Chang, additional, Luo, Jiing-Chyuan, additional, Bair, Ming-Jong, additional, Chen, Po-Yueh, additional, Chou, Chu-Kuang, additional, Fang, Yu-Jen, additional, Chen, Mei-Jyh, additional, Chen, Chien-Chuan, additional, Lee, Ji-Yuh, additional, Yang, Tsung-Hua, additional, Yu, Chien-Chun, additional, Kuo, Chia-Chi, additional, Chiu, Min-Chin, additional, Chen, Chi-Yi, additional, Shun, Chia-Tung, additional, Hu, Wen-Hao, additional, Tsai, Min-Horn, additional, Hsu, Yao-Chun, additional, Tseng, Cheng-Hao, additional, Chang, Chi-Yang, additional, Lin, Jaw-Town, additional, El-Omar, Emad M, additional, Wu, Ming-Shiang, additional, Wu, Chun-Ying, additional, Lee, Yi-Chia, additional, Tseng, Ping-Huei, additional, Wu, Jeng-Yih, additional, Tai, Chi-Ming, additional, Lee, Ching-Tai, additional, and Wang, Wen-Lun, additional

Published
2022
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18. Screening and eradication of Helicobacter pylori to prevent gastric cancer in indigenous Taiwanese communities: a population-based study and development of an index-case method

Author

Lei, Wei-Yi, primary, Lee, Jian-Yu, additional, Chen, Chie-Lin, additional, Bair, Ming-Jong, additional, Wu, Jeng-Yih, additional, Wu, Deng-Chyang, additional, Tien, Hui-Wen, additional, Lin, Li-Ju, additional, Hsuttt, Tsui-Hsia, additional, and Lee, Yi-Chia, additional

Published
2022
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19. 1063: MASS SCREENING AND ERADICATION OF HELICOBACTER PYLORI INFECTION TO REDUCE GASTRIC CANCER FOR INDIGENOUS TAIWANESE PEOPLES: A FEASIBILITY STUDY

Author

Lei, Wei-Yi, primary, Lee, Jian-Yu, additional, Chen, Chien-Lin, additional, Bair, Ming-Jong, additional, Wu, Jeng-Yih, additional, Wu, Deng-Chyang, additional, O'Donnell, Felice Tien, additional, Tien, Hui-Wen, additional, Chen, Yi-Ru, additional, Chuang, Shu-Lin, additional, Chiang, Tsung-Hsien, additional, Hsu, Yu-Hsin, additional, Hsu, Tsui-Hsia, additional, Chu, Chia-Hsiang, additional, Wu, Ming-Shiang, additional, and Lee, Yi-Chia, additional

Published
2022
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21. Exhaled Hydrogen after Lactulose Hydrogen Breath Test in Patient with Duodenal Ulcer Disease—A Pilot Study for Helicobacter-pylori -Associated Gastroduodenal Disease.

Author

Chen, Yi-Hsun, Chen, Sharon Chia-Ju, Wang, Jiunn-Wei, Liu, Chiang-Shin, Wu, Jeng-Yih, Wu, Deng-Chyang, and Su, Yu-Chung

Subjects
DUODENAL ulcers, HELICOBACTER pylori, DUODENAL diseases, BREATH tests, LACTULOSE, GASTRIC mucosa
Abstract

Objectives: The precipitating mechanism(s) from the inactive to the active stage of duodenal ulcer disease (DU) is unclear. It has been shown that hydrogen gas from colonic fermentation provides an important energy source for Helicobacter pylori (Hp) colonization. The lactulose hydrogen breath test (LHBT) is a useful tool to assess the small intestinal and/or colon fermentation. This study examines the association(s) between the status of gastroduodenal disease and the result of a lactulose hydrogen breath test (LHBT). Materials and Methods: We enrolled Hp-positive active duodenal ulcer (aDU) patients, inactive DU (iDU) patients and patients with a positive Hp infection without structural gastroduodenal lesion, i.e., simple gastritis (SG Hp+). The patients with simple gastritis without Hp infection (SG Hp−) served as controls. Histological examinations of the gastric mucosa and lactulose hydrogen breath test (LHBT) were performed. Results: SG Hp+ patients tend to have advanced gastritis (pangastritis or corpus-predominant gastritis) compared with SG Hp− patients (7/29 vs. 0/14, p = 0.08). More iDU patients had advanced gastritis than either the SG Hp+ (7/9 vs. 7/29, p = 0.006) or aDU patients (7/9 vs. 6/24, p = 0.013). In comparison with the aDU patients, the iDU patients were also older (52.1 ± 12.6 vs. 42.2 ± 11.9 years, p = 0.02) and had a lower mean area under the curve value of the LHBT(AUC) (209.1 ± 86.0 vs. 421.9 ± 70.9, p = 0.023). Conclusion: aDU patients with a positive Hp infection have a lower grade of gastric mucosa damage than iDU patients and tend to have a higher level of exhaled hydrogen after LHBT. [ABSTRACT FROM AUTHOR]

Published
2023
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30. Eradicating Helicobacter pylorivia 13C-urea breath screening to prevent gastric cancer in indigenous communities: a population-based study and development of a family index-case method

Author

Lei, Wei-Yi, Lee, Jian-Yu, Chuang, Shu-Ling, Bair, Ming-Jong, Chen, Chien-Lin, Wu, Jeng-Yih, Wu, Deng-Chyang, Tien O’Donnell, Felice, Tien, Hui-Wen, Chen, Yi-Ru, Chiang, Tsung-Hsien, Hsu, Yu-Hsin, Hsu, Tsui-Hsia, Hsieh, Pei-Chun, Lin, Li-Ju, Chia, Shu-Li, Wu, Chao-Chun, Subeq, Yi-Maun, Wen, Shu-Hui, Chang, Hsiu-Chun, Lin, Yu-Wen, Sun, Kuo-Ping, Chu, Chia-Hsiang, Wu, Ming-Shiang, Graham, David Y, Chen, Hsiu-Hsi, and Lee, Yi-Chia

Abstract

ObjectiveScreening and eradication of Helicobacter pylorihelp reduce disparities in the incidence of gastric cancer. We aimed to evaluate its acceptability and feasibility in the indigenous communities and develop a family index-case method to roll out this programme.DesignWe enrolled residents aged 20–60 years from Taiwanese indigenous communities to receive a course of test, treat, retest and re-treat initial treatment failures with the 13C-urea breath tests and four-drug antibiotic treatments. We also invited the family members of a participant (constituting an index case) to join the programme and evaluated whether the infection rate would be higher in the positive index cases.ResultsBetween 24 September 2018 and 31 December 2021, 15 057 participants (8852 indigenous and 6205 non-indigenous) were enrolled, with a participation rate of 80.0% (15 057 of 18 821 invitees). The positivity rate was 44.1% (95% CI 43.3% to 44.9%). In the proof-of-concept study with 72 indigenous families (258 participants), family members of a positive index case had 1.98 times (95% CI 1.03 to 3.80) higher prevalence of H. pylorithan those of a negative index case. The results were replicated in the mass screening setting (1.95 times, 95% CI 1.61 to 2.36) when 1115 indigenous and 555 non-indigenous families were included (4157 participants). Of the 6643 testing positive, 5493 (82.6%) received treatment. According to intention-to-treat and per-protocol analyses, the eradication rates were 91.7% (89.1% to 94.3%) and 92.1% (89.2% to 95.0%), respectively, after one to two courses of treatment. The rate of adverse effects leading to treatment discontinuation was low at 1.2% (0.9% to 1.5%).ConclusionA high participation rate, a high eradication rate of H. pyloriand an efficient rollout method indicate that a primary prevention strategy is acceptable and feasible in indigenous communities.Trial registration numberNCT03900910.

Published
2023
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31. The peopling of the pacific from a bacterial perspective

Author

Moodley, Yoshan, Linz, Bodo, Yamaoka, Yoshio, Windsor, Helen M., Breurec, Sebastien, Wu, Jeng-Yih, Maady, Ayas, Bernhoft, Steffie, Thiberge, Jean-Michel, Phuanukoonnon, Suparat, Jobb, Gangolf, Siba, Peter, Graham, David Y., Marshall, Barry J., and Achtman, Mark

Subjects
Divergent evolution -- Research, Helicobacter pylori -- Distribution, Company distribution practices, Science and technology
Abstract

Two prehistoric migrations peopled the Pacific. One reached New Guinea and Australia, and a second, more recent, migration extended through Melanesia and from there to the Polynesian islands. These migrations were accompanied by two distinct populations of the specific human pathogen Helicobacter pylori, called hpSahul and hspMaori, respectively, hpSahul split from Asian populations of H. pylori 31,000 to 37,000 years ago, in concordance with archaeological history. The hpSahul populations in New Guinea and Australia have diverged sufficiently to indicate that they have remained isolated for the past 23,000 to 32,000 years. The second human expansion from Taiwan 5000 years ago dispersed one of several subgroups of the Austronesian language family along with one of several hspMaori clades into Melanesia and Polynesia, where both language and parasite have continued to diverge.

Published
2009

35. Efficacy of genotypic resistance-guided sequential therapy in the third-line treatment of refractory Helicobacter pylori infection: a multicentre clinical trial

Author

Liou, Jyh-Ming, Chen, Chieh-Chang, Chang, Chi-Yang, Chen, Mei-Jyh, Fang, Yu-Jen, Lee, Ji-Yuh, Chen, Chien-Chuan, Hsu, Shih-Jer, Hsu, Yao-Chun, Tseng, Cheng-Hao, Tseng, Ping-Huei, Chang, Lawrence, Chang, Wen-Hsiung, Wang, Hsiu-Po, Shun, Chia-Tung, Wu, Jeng-Yih, Lee, Yi-Chia, Lin, Jaw-Town, and Wu, Ming-Shiang

Published
2013
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36. Percutaneous transhepatic gallbladder drainage facilitates endoscopic transpapillary gallbladder drainage in patients with acute cholecystitis

Author

Hsieh, Meng‐Shu, Shih, Hsiang‐Yao, Hsu, Wen‐Hung, Yu, Fang‐Jung, Wang, Yao‐Kuang, and Wu, Jeng‐Yih

Abstract

Drainage of gallbladder is important for the management of acute cholecystitis in inoperable elderly patients. Endoscopic transpapillary gallbladder drainage (ETGBD) is an ideal option because this internal drainage has more advantages such as life convenience, no need for exchange of the tube and low possibility of tube dislodgement, compared with external drainage such as percutaneous transhepatic gallbladder drainage (PTGBD). However, ETGBD is challenging because it demands competence in ERCP skills. Moreover, for patients with biliary tract infection, the biliary tract is inflamed, edematous and full of sticky dirty bile, causing selective cannulation into cystic duct more difficult and low successful rates of ETGBD. Herein, we hypothesized that the drainage with PTGBD attenuates the biliary inflammation and facilitates the subsequent ETGBD. Therefore, we conducted this retrospective study to compare the clinical outcomes, procedure outcomes and complications of ETGBD in patients of cholecystitis with and without prior PTGBD. Nineteen patients of acute cholecystitis were retrospectively included. Ten of them had no PTGBD while nine of them had PTGBD based on clinical conditions. All of them underwent ETGBD either for drainage or for infectious source control or for converting external drainage to internal drainage. Basic demographics, laboratory data, procedure time, technical success, early clinical success and complications were compared in both groups. Baseline demographics, pre‐procedural laboratory data (bilirubin, C‐reactive protein) were similar in both groups. ETGBD was technically successful in eight of the nine patients with PTGBD, superior to those without prior PTGBD (88.9% vs 70%, P= .31). The early clinical success rates of PTGBD group were both 100%. The procedure time of ETGBD was shorter in PTGBD group (28.4 minutes vs 39.4 minutes, P= .09). The rates of significant post‐ERCP hyperamylasemia/hyperlipasemia was lower in PTGBD group (22.2% vs 30.0%, P= .7). On the analysis of logistic regression, the odd ratio of technical success was 3.4 in PTGBD group. Our study demonstrated that ETGBD was easier to perform in patients with PTGBD. After the infection source is controlled with PTGBD, selective cannulation into cystic duct seems to be easier to manipulate. Beside higher technical success rate, ETGBD in patients with PTGBD required shorter procedure time and contributed to less complications. Although the statistics was not significant, yet the trend toward to the superiority in PTGBD group was confirmed. Consequently, PTGBD possibly facilitates ETGBD insertion in patients with acute cholecystitis.

Published
2022
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41. Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus

Author

Liou, Jyh-Ming, primary, Malfertheiner, Peter, additional, Lee, Yi-Chia, additional, Sheu, Bor-Shyang, additional, Sugano, Kentaro, additional, Cheng, Hsiu-Chi, additional, Yeoh, Khay-Guan, additional, Hsu, Ping-I, additional, Goh, Khean-Lee, additional, Mahachai, Varocha, additional, Gotoda, Takuji, additional, Chang, Wei-Lun, additional, Chen, Mei-Jyh, additional, Chiang, Tsung-Hsien, additional, Chen, Chieh-Chang, additional, Wu, Chun-Ying, additional, Leow, Alex Hwong-Ruey, additional, Wu, Jeng-Yih, additional, Wu, Deng-Chyang, additional, Hong, Tzu-Chan, additional, Lu, Hong, additional, Yamaoka, Yoshio, additional, Megraud, Francis, additional, Chan, Francis K L, additional, Sung, Joseph JY, additional, Lin, Jaw-Town, additional, Graham, David Y, additional, Wu, Ming-Shiang, additional, and El-Omar, Emad M, additional

Published
2020
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