440 results on '"Wu, Felicia"'
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2. Aflatoxin M1 in milk and dairy products: The state of the evidence for child growth impairment
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Hsu, Patricia, Pokharel, Ashish, Scott, Christian Kelly, and Wu, Felicia
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- 2024
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3. Food Safety Research and Extension Needs for the U.S. Low-Moisture Food Industry
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Chen, Han, Anderson, Nathan M., Grasso-Kelley, Elizabeth M., Harris, Linda J., Marks, Bradley P., McGowen, Lindsey, Scharff, Robert L., Subbiah, Jeyamkondan, Tang, Juming, Wu, Felicia, and Feng, Yaohua
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- 2024
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4. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050
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Naghavi, Mohsen, Vollset, Stein Emil, Ikuta, Kevin S, Swetschinski, Lucien R, Gray, Authia P, Wool, Eve E, Robles Aguilar, Gisela, Mestrovic, Tomislav, Smith, Georgia, Han, Chieh, Hsu, Rebecca L, Chalek, Julian, Araki, Daniel T, Chung, Erin, Raggi, Catalina, Gershberg Hayoon, Anna, Davis Weaver, Nicole, Lindstedt, Paulina A, Smith, Amanda E, Altay, Umut, Bhattacharjee, Natalia V, Giannakis, Konstantinos, Fell, Frederick, McManigal, Barney, Ekapirat, Nattwut, Mendes, Jessica Andretta, Runghien, Tilleye, Srimokla, Oraya, Abdelkader, Atef, Abd-Elsalam, Sherief, Aboagye, Richard Gyan, Abolhassani, Hassan, Abualruz, Hasan, Abubakar, Usman, Abukhadijah, Hana J, Aburuz, Salahdein, Abu-Zaid, Ahmed, Achalapong, Sureerak, Addo, Isaac Yeboah, Adekanmbi, Victor, Adeyeoluwa, Temitayo Esther, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afzal, Muhammad Sohail, Afzal, Saira, Agodi, Antonella, Ahlstrom, Austin J, Ahmad, Aqeel, Ahmad, Sajjad, Ahmad, Tauseef, Ahmadi, Ali, Ahmed, Ayman, Ahmed, Haroon, Ahmed, Ibrar, Ahmed, Mohammed, Ahmed, Saeed, Ahmed, Syed Anees, Akkaif, Mohammed Ahmed, Al Awaidy, Salah, Al Thaher, Yazan, Alalalmeh, Samer O, AlBataineh, Mohammad T, Aldhaleei, Wafa A, Al-Gheethi, Adel Ali Saeed, Alhaji, Nma Bida, Ali, Abid, Ali, Liaqat, Ali, Syed Shujait, Ali, Waad, Allel, Kasim, Al-Marwani, Sabah, Alrawashdeh, Ahmad, Altaf, Awais, Al-Tammemi, Alaa B., Al-Tawfiq, Jaffar A, Alzoubi, Karem H, Al-Zyoud, Walid Adnan, Amos, Ben, Amuasi, John H, Ancuceanu, Robert, Andrews, Jason R, Anil, Abhishek, Anuoluwa, Iyadunni Adesola, Anvari, Saeid, Anyasodor, Anayochukwu Edward, Apostol, Geminn Louis Carace, Arabloo, Jalal, Arafat, Mosab, Aravkin, Aleksandr Y, Areda, Demelash, Aremu, Abdulfatai, Artamonov, Anton A, Ashley, Elizabeth A, Asika, Marvellous O, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Awoke, Tewachew, Azadnajafabad, Sina, Azam, James Mba, Aziz, Shahkaar, Azzam, Ahmed Y., Babaei, Mahsa, Babin, Francois-Xavier, Badar, Muhammad, Baig, Atif Amin, Bajcetic, Milica, Baker, Stephen, Bardhan, Mainak, Barqawi, Hiba Jawdat, Basharat, Zarrin, Basiru, Afisu, Bastard, Mathieu, Basu, Saurav, Bayleyegn, Nebiyou Simegnew, Belete, Melaku Ashagrie, Bello, Olorunjuwon Omolaja, Beloukas, Apostolos, Berkley, James A, Bhagavathula, Akshaya Srikanth, Bhaskar, Sonu, Bhuyan, Soumitra S, Bielicki, Julia A, Briko, Nikolay Ivanovich, Brown, Colin Stewart, Browne, Annie J, Buonsenso, Danilo, Bustanji, Yasser, Carvalheiro, Cristina G, Castañeda-Orjuela, Carlos A, Cenderadewi, Muthia, Chadwick, Joshua, Chakraborty, Sandip, Chandika, Rama Mohan, Chandy, Sara, Chansamouth, Vilada, Chattu, Vijay Kumar, Chaudhary, Anis Ahmad, Ching, Patrick R, Chopra, Hitesh, Chowdhury, Fazle Rabbi, Chu, Dinh-Toi, Chutiyami, Muhammad, Cruz-Martins, Natalia, da Silva, Alanna Gomes, Dadras, Omid, Dai, Xiaochen, Darcho, Samuel D, Das, Saswati, De la Hoz, Fernando Pio, Dekker, Denise Myriam, Dhama, Kuldeep, Diaz, Daniel, Dickson, Benjamin Felix Rothschild, Djorie, Serge Ghislain, Dodangeh, Milad, Dohare, Sushil, Dokova, Klara Georgieva, Doshi, Ojas Prakashbhai, Dowou, Robert Kokou, Dsouza, Haneil Larson, Dunachie, Susanna J, Dziedzic, Arkadiusz Marian, Eckmanns, Tim, Ed-Dra, Abdelaziz, Eftekharimehrabad, Aziz, Ekundayo, Temitope Cyrus, El Sayed, Iman, Elhadi, Muhammed, El-Huneidi, Waseem, Elias, Christelle, Ellis, Sally J, Elsheikh, Randa, Elsohaby, Ibrahim, Eltaha, Chadi, Eshrati, Babak, Eslami, Majid, Eyre, David William, Fadaka, Adewale Oluwaseun, Fagbamigbe, Adeniyi Francis, Fahim, Ayesha, Fakhri-Demeshghieh, Aliasghar, Fasina, Folorunso Oludayo, Fasina, Modupe Margaret, Fatehizadeh, Ali, Feasey, Nicholas A, Feizkhah, Alireza, Fekadu, Ginenus, Fischer, Florian, Fitriana, Ida, Forrest, Karen M, Fortuna Rodrigues, Celia, Fuller, John E, Gadanya, Muktar A, Gajdács, Márió, Gandhi, Aravind P, Garcia-Gallo, Esteban E, Garrett, Denise O, Gautam, Rupesh K, Gebregergis, Miglas Welay, Gebrehiwot, Mesfin, Gebremeskel, Teferi Gebru, Geffers, Christine, 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Hyon Jin, Jokar, Mohammad, Jomehzadeh, Nabi, Joo, Tamas, Joseph, Nitin, Kamal, Zul, Kanmodi, Kehinde Kazeem, Kantar, Rami S, Kapisi, James Apollo, Karaye, Ibraheem M, Khader, Yousef Saleh, Khajuria, Himanshu, Khalid, Nauman, Khamesipour, Faham, Khan, Ajmal, Khan, Mohammad Jobair, Khan, Muhammad Tariq, Khanal, Vishnu, Khidri, Feriha Fatima, Khubchandani, Jagdish, Khusuwan, Suwimon, Kim, Min Seo, Kisa, Adnan, Korshunov, Vladimir Andreevich, Krapp, Fiorella, Krumkamp, Ralf, Kuddus, Mohammed, Kulimbet, Mukhtar, Kumar, Dewesh, Kumaran, Emmanuelle A P, Kuttikkattu, Ambily, Kyu, Hmwe Hmwe, Landires, Iván, Lawal, Basira Kankia, Le, Thao Thi Thu, Lederer, Ingeborg Maria, Lee, Munjae, Lee, Seung Won, Lepape, Alain, Lerango, Temesgen Leka, Ligade, Virendra S, Lim, Cherry, Lim, Stephen S, Limenh, Liknaw Workie, Liu, Chaojie, Liu, Xiaofeng, Liu, Xuefeng, Loftus, Michael J, M Amin, Hawraz Ibrahim, Maass, Kelsey Lynn, Maharaj, Sandeep B, Mahmoud, Mansour Adam, Maikanti-Charalampous, Panagiota, Makram, Omar M, Malhotra, Kashish, Malik, Ahmad Azam, Mandilara, Georgia D, Marks, Florian, Martinez-Guerra, Bernardo Alfonso, Martorell, Miquel, Masoumi-Asl, Hossein, Mathioudakis, Alexander G, May, Juergen, McHugh, Theresa A, Meiring, James, Meles, Hadush Negash, Melese, Addisu, Melese, Endalkachew Belayneh, Minervini, Giuseppe, Mohamed, Nouh Saad, Mohammed, Shafiu, Mohan, Syam, Mokdad, Ali H, Monasta, Lorenzo, Moodi Ghalibaf, AmirAli, Moore, Catrin E, Moradi, Yousef, Mossialos, Elias, Mougin, Vincent, Mukoro, George Duke, Mulita, Francesk, Muller-Pebody, Berit, Murillo-Zamora, Efren, Musa, Sani, Musicha, Patrick, Musila, Lillian A, Muthupandian, Saravanan, Nagarajan, Ahamarshan Jayaraman, Naghavi, Pirouz, Nainu, Firzan, Nair, Tapas Sadasivan, Najmuldeen, Hastyar Hama Rashid, Natto, Zuhair S, Nauman, Javaid, Nayak, Biswa Prakash, Nchanji, G Takop, Ndishimye, Pacifique, Negoi, Ionut, Negoi, Ruxandra Irina, Nejadghaderi, Seyed Aria, Nguyen, QuynhAnh P, Noman, Efaq Ali, Nwakanma, Davis C, O'Brien, Seamus, Ochoa, Theresa J, Odetokun, Ismail A, Ogundijo, Oluwaseun Adeolu, Ojo-Akosile, Tolulope R, Okeke, Sylvester Reuben, Okonji, Osaretin Christabel, Olagunju, Andrew T, Olivas-Martinez, Antonio, Olorukooba, Abdulhakeem Abayomi, Olwoch, Peter, Onyedibe, Kenneth Ikenna, Ortiz-Brizuela, Edgar, Osuolale, Olayinka, Ounchanum, Pradthana, Oyeyemi, Oyetunde T, P A, Mahesh Padukudru, Paredes, Jose L, Parikh, Romil R, Patel, Jay, Patil, Shankargouda, Pawar, Shrikant, Peleg, Anton Y, Peprah, Prince, Perdigão, João, Perrone, Carlo, Petcu, Ionela-Roxana, Phommasone, Koukeo, Piracha, Zahra Zahid, Poddighe, Dimitri, Pollard, Andrew J, Poluru, Ramesh, Ponce-De-Leon, Alfredo, Puvvula, Jagadeesh, Qamar, Farah Naz, Qasim, Nameer Hashim, Rafai, Clotaire Donatien, Raghav, Pankaja, Rahbarnia, Leila, Rahim, Fakher, Rahimi-Movaghar, Vafa, Rahman, Mosiur, Rahman, Muhammad Aziz, Ramadan, Hazem, Ramasamy, Shakthi Kumaran, Ramesh, Pushkal Sinduvadi, Ramteke, Pramod W, Rana, Rishabh Kumar, Rani, Usha, Rashidi, Mohammad-Mahdi, Rathish, Devarajan, Rattanavong, Sayaphet, Rawaf, Salman, Redwan, Elrashdy Moustafa Mohamed, Reyes, Luis Felipe, Roberts, Tamalee, Robotham, Julie V, Rosenthal, Victor Daniel, Ross, Allen Guy, Roy, Nitai, Rudd, Kristina E, Sabet, Cameron John, Saddik, Basema Ahmad, Saeb, Mohammad Reza, Saeed, Umar, Saeedi Moghaddam, Sahar, Saengchan, Weeravoot, Safaei, Mohsen, Saghazadeh, Amene, Saheb Sharif-Askari, Narjes, Sahebkar, Amirhossein, Sahoo, Soumya Swaroop, Sahu, Maitreyi, Saki, Morteza, Salam, Nasir, Saleem, Zikria, Saleh, Mohamed A, Samodra, Yoseph Leonardo, Samy, Abdallah M, Saravanan, Aswini, Satpathy, Maheswar, Schumacher, Austin E, Sedighi, Mansour, Seekaew, Samroeng, Shafie, Mahan, Shah, Pritik A, Shahid, Samiah, Shahwan, Moyad Jamal, Shakoor, Sadia, Shalev, Noga, Shamim, Muhammad Aaqib, Shamshirgaran, Mohammad Ali, Shamsi, Anas, Sharifan, Amin, Shastry, Rajesh P, Shetty, Mahabalesh, Shittu, Aminu, Shrestha, Sunil, Siddig, Emmanuel Edwar, Sideroglou, Theologia, Sifuentes-Osornio, Jose, Silva, Luís Manuel Lopes Rodrigues, Simões, Eric A F, Simpson, Andrew J H, Singh, Amit, Singh, Surjit, Sinto, Robert, Soliman, Sameh S M, Soraneh, Soroush, Stoesser, Nicole, Stoeva, Temenuga Zhekova, Swain, Chandan Kumar, Szarpak, Lukasz, T Y, Sree Sudha, Tabatabai, Shima, Tabche, Celine, Taha, Zanan Mohammed-Ameen, Tan, Ker-Kan, Tasak, Nidanuch, Tat, Nathan Y, Thaiprakong, Areerat, Thangaraju, Pugazhenthan, Tigoi, Caroline Chepngeno, Tiwari, Krishna, Tovani-Palone, Marcos Roberto, Tran, Thang Huu, Tumurkhuu, Munkhtuya, Turner, Paul, Udoakang, Aniefiok John, Udoh, Arit, Ullah, Noor, Ullah, Saeed, Vaithinathan, Asokan Govindaraj, Valenti, Mario, Vos, Theo, Vu, Huong T L, Waheed, Yasir, Walker, Ann Sarah, Walson, Judd L, Wangrangsimakul, Tri, Weerakoon, Kosala Gayan, Wertheim, Heiman F L, Williams, Phoebe C M, Wolde, Asrat Arja, Wozniak, Teresa M, Wu, Felicia, Wu, Zenghong, Yadav, Mukesh Kumar Kumar, Yaghoubi, Sajad, Yahaya, Zwanden Sule, Yarahmadi, Amir, Yezli, Saber, Yismaw, Yazachew Engida, Yon, Dong Keon, Yuan, Chun-Wei, Yusuf, Hadiza, Zakham, Fathiah, Zamagni, Giulia, Zhang, Haijun, Zhang, Zhi-Jiang, Zielińska, Magdalena, Zumla, Alimuddin, Zyoud, Sa'ed H. H, Zyoud, Samer H, Hay, Simon I, Stergachis, Andy, Sartorius, Benn, Cooper, Ben S, Dolecek, Christiane, and Murray, Christopher J L
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- 2024
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5. Feed handling practices, aflatoxin awareness and children's milk consumption in the Sidama region of southern Ethiopia
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Anato, Anchamo, Headey, Derek, Hirvonen, Kalle, Pokharel, Ashish, Tessema, Masresha, Wu, Felicia, and Baye, Kaleab
- Published
- 2024
- Full Text
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6. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Brauer, Michael, Roth, Gregory A, Aravkin, Aleksandr Y, Zheng, Peng, Abate, Kalkidan Hassen, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasi, Madineh Akram, Abbasian, Mohammadreza, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abd ElHafeez, Samar, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdulah, Deldar Morad, Abdullahi, Auwal, Abebe, Mesfin, Abedi, Aidin, Abedi, Armita, Abegaz, Tadesse M, Abeldaño Zuñiga, Roberto Ariel, Abiodun, Olumide, Abiso, Temesgen Lera, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abukhadijah, Hana Jihad Jihad, Aburuz, Salahdein, Abu-Zaid, Ahmed, Adane, Mesafint Molla, Addo, Isaac Yeboah, Addolorato, Giovanni, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Aden, Bashir, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adibi, Amin, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afolabi, Aanuoluwapo Adeyimika, Afolabi, Rotimi Felix, Afshin, Ashkan, Afyouni, Shadi, Afzal, Muhammad Sohail, Afzal, Saira, Agampodi, Suneth Buddhika, Agbozo, Faith, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Firdos, Ahmad, Noah, Ahmad, Shahzaib, Ahmad, Tauseef, Ahmed, Ali, Ahmed, Anisuddin, Ahmed, Ayman, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed, Safoora, Ahmed, Syed Anees, Ajami, Marjan, Akalu, Gizachew Taddesse, Akara, Essona Matatom, Akbarialiabad, Hossein, Akhlaghi, Shiva, Akinosoglou, Karolina, Akinyemiju, Tomi, Akkaif, Mohammed Ahmed, Akkala, Sreelatha, Akombi-Inyang, Blessing, Al Awaidy, Salah, Al Hasan, Syed Mahfuz, Alahdab, Fares, AL-Ahdal, Tareq Mohammed Ali, Alalalmeh, Samer O, Alalwan, Tariq A, Al-Aly, Ziyad, Alam, Khurshid, Alam, Nazmul, Alanezi, Fahad Mashhour, Alanzi, Turki M, Albakri, Almaza, AlBataineh, Mohammad T, Aldhaleei, Wafa A, Aldridge, Robert W, Alemayohu, Mulubirhan Assefa, Alemu, Yihun Mulugeta, Al-Fatly, Bassam, Al-Gheethi, Adel Ali Saeed, Al-Habbal, Khairat, Alhabib, Khalid F, Alhassan, Robert Kaba, Ali, Abid, Ali, Amjad, Ali, Beriwan Abdulqadir, Ali, Iman, Ali, Liaqat, Ali, Mohammed Usman, Ali, Rafat, Ali, Syed Shujait Shujait, Ali, Waad, Alicandro, Gianfranco, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Alla, François, Al-Marwani, Sabah, Al-Mekhlafi, Hesham M, Almustanyir, Sami, Alomari, Mahmoud A, Alonso, Jordi, Alqahtani, Jaber S, Alqutaibi, Ahmed Yaseen, Al-Raddadi, Rajaa M, Alrawashdeh, Ahmad, Al-Rifai, Rami Hani, Alrousan, Sahel Majed, Al-Sabah, Salman Khalifah, Alshahrani, Najim Z, Altaany, Zaid, Altaf, Awais, Al-Tawfiq, Jaffar A, Altirkawi, Khalid A, Aluh, Deborah Oyine, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Alwafi, Hassan, Al-Wardat, Mohammad Sami, Al-Worafi, Yaser Mohammed, Aly, Hany, Aly, Safwat, Alzoubi, Karem H, Al-Zyoud, Walid, Amaechi, Uchenna Anderson, Aman Mohammadi, Masous, Amani, Reza, Amiri, Sohrab, Amirzade-Iranaq, Mohammad Hosein, Ammirati, Enrico, Amu, Hubert, Amugsi, Dickson A, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderlini, Deanna, Anderson, Jason A, Andrade, Pedro Prata, Andrei, Catalina Liliana, Andrei, Tudorel, Anenberg, Susan C, Angappan, Dhanalakshmi, Angus, Colin, Anil, Abhishek, Anil, Sneha, Anjum, Afifa, Anoushiravani, Amir, Antonazzo, Ippazio Cosimo, Antony, Catherine M, Antriyandarti, Ernoiz, Anuoluwa, Boluwatife Stephen, Anvari, Davood, Anvari, Saeid, Anwar, Saleha, Anwar, Sumadi Lukman, Anwer, Razique, Anyabolo, Ekenedilichukwu Emmanuel, Anyasodor, Anayochukwu Edward, Apostol, Geminn Louis Carace, Arabloo, Jalal, Arabzadeh Bahri, Razman, Arafat, Mosab, Areda, Demelash, Aregawi, Brhane Berhe, Aremu, Abdulfatai, Armocida, Benedetta, Arndt, Michael Benjamin, Ärnlöv, Johan, Arooj, Mahwish, Artamonov, Anton A, Artanti, Kurnia Dwi, Aruleba, Idowu Thomas, Arumugam, Ashokan, Asbeutah, Akram M, Asgary, Saeed, Asgedom, Akeza Awealom, Ashbaugh, Charlie, Ashemo, Mubarek Yesse, Ashraf, Tahira, Askarinejad, Amir, Assmus, Michael, Astell-Burt, Thomas, Athar, Mohammad, Athari, Seyyed Shamsadin, Atorkey, Prince, Atreya, Alok, Aujayeb, Avinash, Ausloos, Marcel, Avila-Burgos, Leticia, Awoke, Andargie Abate, Ayala Quintanilla, Beatriz Paulina, Ayatollahi, Haleh, Ayestas Portugal, Carlos, Ayuso-Mateos, Jose L, Azadnajafabad, Sina, Azevedo, Rui M S, Azhar, Gulrez Shah, Azizi, Hosein, Azzam, Ahmed Y, Backhaus, Insa Linnea, Badar, Muhammad, Badiye, Ashish D, Bagga, Arvind, Baghdadi, Soroush, Bagheri, Nasser, Bagherieh, Sara, Bahrami Taghanaki, Pegah, Bai, Ruhai, Baig, Atif Amin, Baker, Jennifer L, Bakkannavar, Shankar M, Balasubramanian, Madhan, Baltatu, Ovidiu Constantin, Bam, Kiran, Bandyopadhyay, Soham, Banik, Biswajit, Banik, Palash Chandra, Banke-Thomas, Aduragbemi, Bansal, Hansi, Barchitta, Martina, Bardhan, Mainak, Bardideh, Erfan, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barone-Adesi, Francesco, Barqawi, Hiba Jawdat, Barrero, Lope H, Barrow, Amadou, Barteit, Sandra, Basharat, Zarrin, Basiru, Afisu, Basso, João Diogo, Bastan, Mohammad-Mahdi, Basu, Sanjay, Batchu, Sai, Batra, Kavita, Batra, Ravi, Baune, Bernhard T, Bayati, Mohsen, Bayileyegn, Nebiyou Simegnew, Beaney, Thomas, Behnoush, Amir Hossein, Beiranvand, Maryam, Béjot, Yannick, Bekele, Alehegn, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Bell, Michelle L, Bello, Muhammad Bashir, Bello, Olorunjuwon Omolaja, Belo, Luis, Beloukas, Apostolos, Bendak, Salaheddine, Bennett, Derrick A, Bennitt, Fiona B, Bensenor, Isabela M, Benzian, Habib, Beran, Azizullah, Berezvai, Zombor, Bernabe, Eduardo, Bernstein, Robert S, Bettencourt, Paulo J G, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Dinesh, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bhat, Vivek, Bhatti, Gurjit Kaur, Bhatti, Jasvinder Singh, Bhatti, Manpreet S, Bhatti, Rajbir, Bhuiyan, Mohiuddin Ahmed, Bhutta, Zulfiqar A, Bikbov, Boris, Bishai, Jessica Devin, Bisignano, Catherine, Biswas, Atanu, Biswas, Bijit, Biswas, Raaj Kishore, Bjørge, Tone, Boachie, Micheal Kofi, Boakye, Hosea, Bockarie, Moses John, Bodolica, Virginia, Bodunrin, Aadam Olalekan, Bogale, Eyob Ketema, Bolla, Srinivasa Rao, Boloor, Archith, Bonakdar Hashemi, Milad, Boppana, Sri Harsha, Bora Basara, Berrak, Borhany, Hamed, Botero Carvajal, Alejandro, Bouaoud, Souad, Boufous, Soufiane, Bourne, Rupert, Boxe, Christopher, Braithwaite, Dejana, Brant, Luisa C, Brar, Amanpreet, Breitborde, Nicholas J K, Breitner, Susanne, Brenner, Hermann, Briko, Andrey Nikolaevich, Britton, Gabrielle, Brown, Colin Stewart, Browne, Annie J, Brunoni, Andre R, Bryazka, Dana, Bulamu, Norma B, Bulto, Lemma N, Buonsenso, Danilo, Burkart, Katrin, Burns, Richard A, Busse, Reinhard, Bustanji, Yasser, Butt, Nadeem Shafique, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cagney, Jack, Cahuana-Hurtado, Lucero, Calina, Daniela, Cámera, Luis Alberto, Campos, Luciana Aparecida, Campos-Nonato, Ismael R, Cao, Chao, Cao, Fan, Cao, Yubin, Capodici, Angelo, Cárdenas, Rosario, Carr, Sinclair, Carreras, Giulia, Carrero, Juan J, Carugno, Andrea, Carvalho, Felix, Carvalho, Márcia, Castaldelli-Maia, Joao Mauricio, Castañeda-Orjuela, Carlos A, Castelpietra, Giulio, Catalá-López, Ferrán, Catapano, Alberico L, Cattaruzza, Maria Sofia, Caye, Arthur, Cederroth, Christopher R, Cegolon, Luca, Cenderadewi, Muthia, Cercy, Kelly M, Cerin, Ester, Chadwick, Joshua, Chakraborty, Chiranjib, Chakraborty, Promit Ananyo, Chakraborty, Sandip, Chan, Jeffrey Shi Kai, Chan, Raymond N C, Chandan, Joht Singh, Chandika, Rama Mohan, Chaturvedi, Pankaj, Chen, An-Tian, Chen, Catherine S, Chen, Haowei, Chen, Meng Xuan, Chen, Mingling, Chen, Simiao, Cheng, Ching-Yu, Cheng, Esther T W, Cherbuin, Nicolas, Chi, Gerald, Chichagi, Fatemeh, Chimed-Ochir, Odgerel, Chimoriya, Ritesh, Ching, Patrick R, Chirinos-Caceres, Jesus Lorenzo, Chitheer, Abdulaal, Cho, William C S, Chong, Bryan, Chopra, Hitesh, Chowdhury, Rajiv, 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Samer H, Murray, Christopher J L, and Gakidou, Emmanuela
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7. Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
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Vollset, Stein Emil, Ababneh, Hazim S, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbastabar, Hedayat, Abd Al Magied, Abdallah H A, Abd ElHafeez, Samar, Abdelkader, Atef, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdi, Parsa, Abdollahi, Mohammad, Abdoun, Meriem, Abdullahi, Auwal, Abebe, Mesfin, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Absalan, Abdorrahim, Abualruz, Hasan, Abubakar, Bilyaminu, Abukhadijah, Hana Jihad Jihad, Addolorato, Giovanni, Adekanmbi, Victor, Adetunji, Charles Oluwaseun, Adetunji, Juliana Bunmi, Adeyeoluwa, Temitayo Esther, Adha, Rishan, Adhikary, Ripon Kumar, Adnani, Qorinah Estiningtyas Sakilah, Adzigbli, Leticia Akua, Afrashteh, Fatemeh, Afzal, Muhammad Sohail, Afzal, Saira, Agbozo, Faith, Agodi, Antonella, Agrawal, Anurag, Agyemang-Duah, Williams, Ahinkorah, Bright Opoku, Ahlstrom, Austin J, Ahmad, Aqeel, Ahmad, 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8. Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
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Bhattacharjee, Natalia V, Schumacher, Austin E, Aali, Amirali, Abate, Yohannes Habtegiorgis, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd ElHafeez, Samar, Abd-Elsalam, Sherief, Abdollahi, Mohammad, Abdollahifar, Mohammad-Amin, Abdoun, Meriem, Abdullahi, Auwal, Abebe, Mesfin, Abebe, Samrawit Shawel, Abiodun, Olumide, Abolhassani, Hassan, Abolmaali, Meysam, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abrha, Woldu Aberhe, Abrigo, Michael R M, Abtahi, Dariush, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abu-Rmeileh, Niveen ME, Adal, Tadele Girum Girum, Adane, Mesafint Molla, Adeagbo, Oluwafemi Atanda Adeagbo, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Aden, Bashir, Adepoju, Abiola Victor, Adetokunboh, Olatunji O, Adetunji, Juliana Bunmi, Adeyinka, Daniel Adedayo, Adeyomoye, Olorunsola Israel, Adnani, Qorinah Estiningtyas Sakilah, Adra, Saryia, Afolabi, Rotimi Felix, Afyouni, Shadi, Afzal, Muhammad 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9. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Theo, and Murray, Christopher J L
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10. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Naghavi, Mohsen, Ong, Kanyin Liane, Aali, Amirali, Ababneh, Hazim S, Abate, Yohannes Habtegiorgis, Abbafati, Cristiana, Abbasgholizadeh, Rouzbeh, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd ElHafeez, Samar, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed, Abdollahi, Mohammad, Abdollahifar, Mohammad-Amin, Abdoun, Meriem, Abdulah, Deldar Morad, Abdullahi, Auwal, Abebe, Mesfin, Abebe, Samrawit Shawel, Abedi, Aidin, Abegaz, Kedir Hussein, Abhilash, E S, Abidi, Hassan, Abiodun, Olumide, Aboagye, Richard Gyan, Abolhassani, Hassan, Abolmaali, Meysam, Abouzid, Mohamed, Aboye, Girma Beressa, Abreu, Lucas Guimarães, Abrha, Woldu Aberhe, Abtahi, Dariush, Abu Rumeileh, Samir, Abualruz, Hasan, Abubakar, Bilyaminu, Abu-Gharbieh, Eman, Abu-Rmeileh, Niveen ME, Aburuz, Salahdein, Abu-Zaid, Ahmed, Accrombessi, Manfred Mario Kokou, Adal, Tadele Girum, Adamu, Abdu A, Addo, Isaac Yeboah, Addolorato, Giovanni, Adebiyi, Akindele Olupelumi, Adekanmbi, Victor, 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Habibzadeh, Farrokh, Habibzadeh, Parham, Haddadi, Rasool, Hadei, Mostafa, Hadi, Najah R, Haep, Nils, Hafezi-Nejad, Nima, Hailu, Alemayehu, Haj-Mirzaian, Arvin, Halboub, Esam S, Hall, Brian J, Haller, Sebastian, Halwani, Rabih, Hamadeh, Randah R, Hameed, Sajid, Hamidi, Samer, Hamilton, Erin B, Han, Chieh, Han, Qiuxia, Hanif, Asif, Hanifi, Nasrin, Hankey, Graeme J, Hanna, Fahad, Hannan, Md Abdul, Haque, Md Nuruzzaman, Harapan, Harapan, Hargono, Arief, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Ikramul, Hasan, M Tasdik, Hasani, Hamidreza, Hasanian, Mohammad, Hashi, Abdiwahab, Hasnain, Md Saquib, Hassan, Ikrama, Hassanipour, Soheil, Hassankhani, Hadi, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, He, Jiawei, Hebert, Jeffrey J, Hegazi, Omar E, Heidari, Golnaz, Heidari, Mohammad, Heidari-Foroozan, Mahsa, Helfer, Bartosz, Hendrie, Delia, Herrera-Serna, Brenda Yuliana, Herteliu, Claudiu, Hesami, Hamed, Hezam, Kamal, Hill, Catherine L, Hiraike, Yuta, Holla, Ramesh, Horita, Nobuyuki, Hossain, Md Mahbub, Hossain, Sahadat, Hosseini, Mohammad-Salar, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hosseinzadeh Adli, Ahmad, Hostiuc, Mihaela, Hostiuc, Sorin, Hsairi, Mohamed, Hsieh, Vivian Chia-rong, Hsu, Rebecca L, Hu, Chengxi, Huang, Junjie, Hultström, Michael, Humayun, Ayesha, Hundie, Tsegaye Gebreyes, Hussain, Javid, Hussain, M Azhar, Hussein, Nawfal R, Hussien, Foziya Mohammed, Huynh, Hong-Han, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ibrahim, Khalid S, Iftikhar, Pulwasha Maria, Ijo, Desta, Ikiroma, Adalia I, Ikuta, Kevin S, Ikwegbue, Paul Chukwudi, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Imam, Mohammad Tarique, Immurana, Mustapha, Inamdar, Sumant, Indriasih, Endang, Iqhrammullah, Muhammad, Iradukunda, Arnaud, Iregbu, Kenneth Chukwuemeka, Islam, Md Rabiul, Islam, Sheikh Mohammed Shariful, Islami, Farhad, Ismail, Faisal, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie C D, Iyamu, Ihoghosa Osamuyi, Iyer, 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A, Khan, M Nuruzzaman, Khan, Maseer, Khan, Mohammad Jobair, Khan, Moien AB, Khan, Zeeshan Ali, Khan suheb, Mahammed Ziauddin, Khanmohammadi, Shaghayegh, Khatab, Khaled, Khatami, Fatemeh, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khavandegar, Armin, Khayat Kashani, Hamid Reza, Khidri, Feriha Fatima, Khodadoust, Elaheh, Khorgamphar, Mohammad, Khormali, Moein, Khorrami, Zahra, Khosravi, Ahmad, Khosravi, Mohammad Ali, Kifle, Zemene Demelash, Kim, Grace, Kim, Jihee, Kim, Kwanghyun, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth W, Kinzel, Kasey E, Kisa, Adnan, Kisa, Sezer, Klu, Desmond, Knudsen, Ann Kristin Skrindo, Kocarnik, Jonathan M, Kochhar, Sonali, Kocsis, Timea, Koh, David S Q, Kolahi, Ali-Asghar, Kolves, Kairi, Kompani, Farzad, Koren, Gerbrand, Kosen, Soewarta, Kostev, Karel, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Krishna, Hare, Krishna, Varun, Krishnamoorthy, Vijay, Krishnamoorthy, Yuvaraj, Krohn, Kris J, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuddus, Md Abdul, Kuddus, Mohammed, Kuitunen, Ilari, Kulimbet, Mukhtar, Kulkarni, Vishnutheertha, Kumar, Akshay, Kumar, Ashish, Kumar, Harish, Kumar, Manasi, Kumar, Rakesh, Kumari, Madhulata, Kumie, Fantahun Tarekegn, Kundu, Satyajit, Kurmi, Om P, Kusnali, Asep, Kusuma, Dian, Kwarteng, Alexander, Kyriopoulos, Ilias, Kyu, Hmwe Hmwe, La Vecchia, Carlo, Lacey, Ben, Ladan, Muhammad Awwal, Laflamme, Lucie, Lagat, Abraham K, Lager, Anton C J, Lahmar, Abdelilah, Lai, Daphne Teck Ching, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lám, Judit, Landrum, Kelsey R, Lanfranchi, Francesco, Lang, Justin J, Langguth, Berthold, Lansingh, Van Charles, Laplante-Lévesque, Ariane, Larijani, Bagher, Larsson, Anders O, Lasrado, Savita, Lassi, Zohra S, Latief, Kamaluddin, Latifinaibin, Kaveh, Lauriola, Paolo, Le, Nhi Huu Hanh, Le, Thao Thi Thu, Le, Trang Diep Thanh, Ledda, Caterina, Ledesma, Jorge R, Lee, Munjae, Lee, Paul H, Lee, Seung Won, Lee, Shaun Wen Huey, Lee, Wei-Chen, Lee, 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Sarikhani, Yaser, Sarkar, Tanmay, Sarmiento-Suárez, Rodrigo, Sarode, Gargi Sachin, Sarode, Sachin C, Sarveazad, Arash, Sathian, Brijesh, Sathish, Thirunavukkarasu, Satpathy, Maheswar, Sayeed, Abu, Sayeed, Md Abu, Saylan, Mete, Sayyah, Mehdi, Scarmeas, Nikolaos, Schaarschmidt, Benedikt Michael, Schlaich, Markus P, Schlee, Winfried, Schmidt, Maria Inês, Schneider, Ione Jayce Ceola, Schuermans, Art, Schumacher, Austin E, Schutte, Aletta Elisabeth, Schwarzinger, Michaël, Schwebel, David C, Schwendicke, Falk, Šekerija, Mario, Selvaraj, Siddharthan, Senapati, Sabyasachi, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Serban, Dragos, Sethi, Yashendra, Sha, Feng, Shabany, Maryam, Shafaat, Amir, Shafie, Mahan, Shah, Nilay S, Shah, Pritik A, Shah, Syed Mahboob, Shahabi, Saeed, Shahbandi, Ataollah, Shahid, Izza, Shahid, Samiah, Shahid, Wajeehah, Shahsavari, Hamid R, Shahwan, Moyad Jamal, Shaikh, Ahmed, Shaikh, Masood Ali, Shakeri, Alireza, Shalash, Ali S, Sham, Sunder, Shamim, Muhammad Aaqib, Shams-Beyranvand, Mehran, Shamshad, Hina, Shamsi, Mohammad Anas, Shanawaz, Mohd, Shankar, Abhishek, Sharfaei, Sadaf, Sharifan, Amin, Sharifi-Rad, Javad, Sharma, Rajesh, Sharma, Saurab, Sharma, Ujjawal, Sharma, Vishal, Shastry, Rajesh P, Shavandi, Amin, Shayan, Maryam, Shehabeldine, Amr Mohamed Elsayed, Sheikh, Aziz, Sheikhi, Rahim Ali, Shen, Jiabin, Shetty, Adithi, Shetty, B Suresh Kumar, Shetty, Pavanchand H, Shi, Peilin, Shibuya, Kenji, Shiferaw, Desalegn, Shigematsu, Mika, Shin, Min-Jeong, Shin, Youn Ho, Shiri, Rahman, Shirkoohi, Reza, Shitaye, Nebiyu Aniley, Shittu, Aminu, Shiue, Ivy, Shivakumar, K M, Shivarov, Velizar, Shokraneh, Farhad, Shokri, Azad, Shool, Sina, Shorofi, Seyed Afshin, Shrestha, Sunil, Shuval, Kerem, Siddig, Emmanuel Edwar, Silva, João Pedro, Silva, Luís Manuel Lopes Rodrigues, Silva, Soraia, Simpson, Colin R, Singal, Anjali, Singh, Abhinav, Singh, Balbir Bagicha, Singh, Garima, Singh, Jasbir, Singh, Narinder Pal, Singh, Paramdeep, Singh, Surjit, Sinha, Dhirendra Narain, Sinto, Robert, Siraj, Md Shahjahan, Sirota, Sarah Brooke, Sitas, Freddy, Sivakumar, Shravan, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sleet, David A, Socea, Bogdan, Sokhan, Anton, Solanki, Ranjan, Solanki, Shipra, Soleimani, Hamidreza, Soliman, Sameh S M, Song, Suhang, Song, Yimeng, Sorensen, Reed J D, Soriano, Joan B, Soyiri, Ireneous N, Spartalis, Michael, Spearman, Sandra, Sreeramareddy, Chandrashekhar T, Srivastava, Vijay Kumar, Stanaway, Jeffrey D, Stanikzai, Muhammad Haroon, Stark, Benjamin A, Starnes, Joseph R, Starodubova, Antonina V, Stein, Caroline, Stein, Dan J, Steinbeis, Fridolin, Steiner, Caitlyn, Steinmetz, Jaimie D, Steiropoulos, Paschalis, Stevanović, Aleksandar, Stockfelt, Leo, Stokes, Mark A, Stortecky, Stefan, Subramaniyan, Vetriselvan, Suleman, Muhammad, Suliankatchi Abdulkader, Rizwan, Sultana, Abida, Sun, Haitong Zhe, Sun, Jing, Sundström, Johan, Sunkersing, David, Sunnerhagen, Katharina S, Swain, Chandan Kumar, Szarpak, Lukasz, Szeto, Mindy D, Szócska, Miklós, Tabaee Damavandi, Payam, Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabatabaei Malazy, Ozra, Tabatabaeizadeh, Seyed-Amir, Tabatabai, Shima, Tabish, Mohammad, TADAKAMADLA, JYOTHI, Tadakamadla, Santosh Kumar, Taheri Abkenar, Yasaman, Taheri Soodejani, Moslem, Taiba, Jabeen, Takahashi, Ken, Talaat, Iman M, Talukder, Ashis, Tampa, Mircea, Tamuzi, Jacques Lukenze, Tan, Ker-Kan, Tandukar, Sarmila, Tang, Haosu, Tang, Hong K, Tarigan, Ingan Ukur, Tariku, Mengistie Kassahun, Tariqujjaman, Md, Tarkang, Elvis Enowbeyang, Tavakoli Oliaee, Razieh, Tavangar, Seyed Mohammad, Taveira, Nuno, Tefera, Yibekal Manaye, Temsah, Mohamad-Hani, Temsah, Reem Mohamad Hani, Teramoto, Masayuki, Tesler, Riki, Teye-Kwadjo, Enoch, Thakur, Rishu, Thangaraju, Pugazhenthan, Thankappan, Kavumpurathu Raman, Tharwat, Samar, Thayakaran, Rasiah, Thomas, Nihal, Thomas, Nikhil Kenny, Thomson, Azalea M, Thrift, Amanda G, Thum, Chern Choong Chern, Thygesen, Lau Caspar, Tian, Jing, Tichopad, Ales, Ticoalu, Jansje Henny Vera, Tillawi, Tala, Tiruye, Tenaw Yimer, Titova, Mariya Vladimirovna, Tonelli, Marcello, Topor-Madry, Roman, Toriola, Adetunji T, Torre, Anna E, Touvier, Mathilde, Tovani-Palone, Marcos Roberto, Tran, Jasmine T, Tran, Nghia Minh, Trico, Domenico, Tromans, Samuel Joseph, Truyen, Thien Tan Tri Tai, Tsatsakis, Aristidis, Tsegay, Guesh Mebrahtom, Tsermpini, Evangelia Eirini, Tumurkhuu, Munkhtuya, Tung, Kang, Tyrovolas, Stefanos, Uddin, Sayed Mohammad Nazim, Udoakang, Aniefiok John, Udoh, Arit, Ullah, Atta, Ullah, Irfan, Ullah, Saeed, Ullah, Sana, Umakanthan, Srikanth, Umeokonkwo, Chukwuma David, Unim, Brigid, Unnikrishnan, Bhaskaran, Unsworth, Carolyn Anne, Upadhyay, Era, Urso, Daniele, Usman, Jibrin Sammani, Vahabi, Seyed Mohammad, Vaithinathan, Asokan Govindaraj, Valizadeh, Rohollah, Van de Velde, Sarah M, Van den Eynde, Jef, Varga, Orsolya, Vart, Priya, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Vasic, Milena, Vaziri, Siavash, Vellingiri, Balachandar, Venketasubramanian, Narayanaswamy, Verghese, Nicholas Alexander, Verma, Madhur, Veroux, Massimiliano, Verras, Georgios-Ioannis, Vervoort, Dominique, Villafañe, Jorge Hugo, Villanueva, Gabriela Ines, Vinayak, Manish, Violante, Francesco S, Viskadourou, Maria, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vo, Bay, Vollset, Stein Emil, Vongpradith, Avina, Vos, Theo, Vujcic, Isidora S, Vukovic, Rade, Wafa, Hatem A, Waheed, Yasir, Wamai, Richard G, Wang, Cong, Wang, Ning, Wang, Shu, Wang, Song, Wang, Yanzhong, Wang, Yuan-Pang, Waqas, Muhammad, Ward, Paul, Wassie, Emebet Gashaw, Watson, Stefanie, Watson, Stephanie Louise Watson, Weerakoon, Kosala Gayan, Wei, Melissa Y, Weintraub, Robert G, Weiss, Daniel J, Westerman, Ronny, Whisnant, Joanna L, Wiangkham, Taweewat, Wickramasinghe, Dakshitha Praneeth, Wickramasinghe, Nuwan Darshana, Wilandika, Angga, Wilkerson, Caroline, Willeit, Peter, Wilson, Shadrach, Wojewodzic, Marcin W, Woldegebreal, Demewoz H, Wolf, Axel Walter, Wolfe, Charles D A, Wondimagegene, Yohannes Addisu, Wong, Yen Jun, Wongsin, Utoomporn, Wu, Ai-Min, Wu, Chenkai, Wu, Felicia, Wu, Xinsheng, Wu, Zenghong, Xia, Juan, Xiao, Hong, Xie, Yang, Xu, Suowen, Xu, Wang-Dong, Xu, Xiaoyue, Xu, Yvonne Yiru, Yadollahpour, Ali, Yamagishi, Kazumasa, Yang, Danting, Yang, Lin, Yano, Yuichiro, Yao, Yao, Yaribeygi, Habib, Ye, Pengpeng, Yehualashet, Sisay Shewasinad, Yesiltepe, Metin, Yesuf, Subah Abderehim, Yezli, Saber, Yi, Siyan, Yigezu, Amanuel, Yiğit, Arzu, Yiğit, Vahit, Yip, Paul, Yismaw, Malede Berihun, Yismaw, Yazachew, Yon, Dong Keon, Yonemoto, Naohiro, Yoon, Seok-Jun, You, Yuyi, Younis, Mustafa Z, Yousefi, Zabihollah, Yu, Chuanhua, Yu, Yong, Yuh, Faith H, Zadey, Siddhesh, Zadnik, Vesna, Zafari, Nima, Zakham, Fathiah, Zaki, Nazar, Zaman, Sojib Bin, Zamora, Nelson, Zand, Ramin, Zangiabadian, Moein, Zar, Heather J, Zare, Iman, Zarrintan, Armin, Zeariya, Mohammed G M, Zeinali, Zahra, Zhang, Haijun, Zhang, Jianrong, Zhang, Jingya, Zhang, Liqun, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Hanqing, Zhong, Chenwen, Zhou, Juexiao, Zhu, Bin, Zhu, Lei, Ziafati, Makan, Zielińska, Magdalena, Zitoun, Osama A, Zoladl, Mohammad, Zou, Zhiyong, Zuhlke, Liesl J, Zumla, Alimuddin, Zweck, Elric, Zyoud, Samer H, Wool, Eve E, and Murray, Christopher J L
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- 2024
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11. Health burden associated with tillage-related PM2.5 pollution in the United States, and mitigation strategies
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Pokharel, Ashish, Hennessy, David A., and Wu, Felicia
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- 2023
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12. Dietary exposure to cadmium from six common foods in the United States
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Pokharel, Ashish and Wu, Felicia
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- 2023
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13. Allow Golden Rice to save lives
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Wu, Felicia, Wesseler, Justus, Zilberman, David, Russell, Robert M., Chen, Chen, and Dubock, Adrian C.
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- 2021
14. Risk Assessment and Regulatory Decision-Making in Environmental Health
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Wu, Felicia, primary and Rodricks, Joseph V., additional
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- 2022
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15. Environmental and economic concerns surrounding restrictions on glyphosate use in corn
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Wu, Felicia and Hennessy, David A.
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- 2021
16. Bt corn and cotton planting may benefit peanut growers by reducing aflatoxin risk.
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Yu, Jina, Hennessy, David A., and Wu, Felicia
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BT cotton ,FOOD crops ,MYCOTOXINS ,TRANSGENIC plants ,INSECT pest control ,PEANUT growing ,DROUGHT management - Abstract
Summary: Decades of studies have shown that Bt corn, by reducing insect damage, has lower levels of mycotoxins (fungal toxins), such as aflatoxin and fumonisin, than conventional corn. We used crop insurance data to infer that this benefit from Bt crops extends to reducing aflatoxin risk in peanuts: a non‐Bt crop. In consequence, we suggest that any benefit–cost assessment of how transgenic Bt crops affect food safety should not be limited to assessing those crops alone; because the insect pest control offered by Bt crops affects the food safety profile of other crops grown nearby. Specifically, we found that higher Bt corn and Bt cotton planting rates in peanut‐growing areas of the United States were associated with lower aflatoxin risk in peanuts as measured by aflatoxin‐related insurance claims filed by peanut growers. Drought‐related insurance claims were also lower: possibly due to Bt crops' suppression of insects that would otherwise feed on roots, rendering peanut plants more vulnerable to drought. These findings have implications for countries worldwide where policies allow Bt cotton but not Bt food crops to be grown: simply planting a Bt crop may reduce aflatoxin and drought stress in nearby food crops, resulting in a safer food supply through an inter‐crop "halo effect." [ABSTRACT FROM AUTHOR]
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- 2024
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17. Effects of aflatoxin on the immune system: Evidence from human and mammalian animal research.
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Saha Turna, Nikita, Comstock, Sarah S., Gangur, Venugopal, and Wu, Felicia
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MYCOTOXINS ,AFLATOXINS ,ASPERGILLUS flavus ,ANIMAL species ,LIVER cancer - Abstract
Shortly after its discovery in 1960, aflatoxin – a group of fungal toxins or mycotoxins produced by the fungi Aspergillus flavus and A. parasiticus in food crops such as maize, peanuts and tree nuts – was found to cause liver cancer in humans and multiple animal species. Hence, regulations on maximum allowable aflatoxin levels in food worldwide have focused on protecting humans from aflatoxin's carcinogenic effects. However, aflatoxin may also have non-carcinogenic health effects (e.g., immunotoxicity) that are particularly relevant today. Our current review highlights the growing evidence that aflatoxin exposure adversely affects immunity. Here, we comprehensively evaluated human and mammalian animal studies that link aflatoxin exposure with adverse effects on the immune system. We organized the review by organism as well as by the effects on adaptive and innate immune functions. There is abundant evidence that aflatoxin exhibits immunotoxicity, and therefore may compromise the ability of both humans and animals to resist infections. However, the reported effects of aflatoxin on certain specific immune biomarkers are inconsistent in the existing literature. The extent of the immunotoxic effects of aflatoxin must be clarified, so that the contribution of such immunotoxicity to the overall burden of aflatoxin-related diseases can be established. [ABSTRACT FROM AUTHOR]
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- 2024
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18. The dry chain: Reducing postharvest losses and improving food safety in humid climates
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Bradford, Kent J, Dahal, Peetambar, Van Asbrouck, Johan, Kunusoth, Keshavulu, Bello, Pedro, Thompson, James, and Wu, Felicia
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Zero Hunger ,Dry chain ,Aflatoxin ,Drying ,Food waste ,Postharvest storage ,Food Sciences ,Food Science - Abstract
Background Even as increasing populations put pressure on food supplies, about one-third of the total food produced for human consumption is wasted, with the majority of loss in developing countries occurring between harvest and the consumer. Controlling product dryness is the most critical factor for maintaining quality in stored non-perishable foods. The high relative humidity prevalent in humid climates elevates the moisture content of dried commodities stored in porous woven bags, enabling fungal and insect infestations. Mycotoxins (e.g., aflatoxin) produced by fungi in insufficiently dried food commodities affect 4.5 billion people worldwide. Scope and approach We introduce the term “dry chain” to describe initial dehydration of durable commodities to levels preventing fungal growth followed by storage in moisture-proof containers. This is analogous to the “cold chain” in which continuous refrigeration is used to preserve quality in the fresh produce industry. However, in the case of the dry chain, no further equipment or energy input is required to maintain product quality after initial drying as long as the integrity of the storage container is preserved. In some locations/seasons, only packaging is required to implement a “climate smart” dry chain, while in humid conditions, additional drying is required and desiccant-based drying methods have unique advantages. Key findings and conclusions We propose both climate-based and drying-based approaches to implement the dry chain to minimize mycotoxin accumulation and insect infestations in dry products, reduce food loss, improve food quality, safety and security, and protect public health.
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- 2018
19. Study protocol to assess aflatoxin M1 health risks versus benefits of dairy consumption in Ethiopian children: an epidemiological trial and risk-benefit analysis
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Wu, Felicia, primary, Headey, Derek, additional, Hirvonen, Kalle, additional, Pokharel, Ashish, additional, and Tessema, Masresha, additional
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- 2024
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20. Global wheat trade and Codex Alimentarius guidelines for deoxynivalenol: A mycotoxin common in wheat
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Chen, Chen, Frank, Kenneth, Wang, Tiancai, and Wu, Felicia
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- 2021
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21. Cost-effectiveness of a wetting method intervention to reduce cassava cyanide-related cognitive impairment in children
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Chen, Chen, Kashala-Abotnes, Espérance, Banea Mayambu, Jean-Pierre, Mumba Ngoyi, Dieudonne, Tshala-Katumbay, Désiré, Mukeba, Daniel, Kunyu, Marcel, Boivin, Michael J., and Wu, Felicia
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- 2021
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22. Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
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Vollset, S, Ababneh, H, Abate, Y, Abbafati, C, Abbasgholizadeh, R, Abbasian, M, Abbastabar, H, Abd Al Magied, A, Abd ElHafeez, S, Abdelkader, A, Abdelmasseh, M, Abd-Elsalam, S, Abdi, P, Abdollahi, M, Abdoun, M, Abdullahi, A, Abebe, M, Abiodun, O, Aboagye, R, Abolhassani, H, Abouzid, M, Aboye, G, Abreu, L, Absalan, A, Abualruz, H, Abubakar, B, Abukhadijah, H, Addolorato, G, Adekanmbi, V, Adetunji, C, Adetunji, J, Adeyeoluwa, T, Adha, R, Adhikary, R, Adnani, Q, Adzigbli, L, Afrashteh, F, Afzal, M, Afzal, S, Agbozo, F, Agodi, A, Agrawal, A, Agyemang-Duah, W, Ahinkorah, B, Ahlstrom, A, Ahmad, A, Ahmad, F, Ahmad, M, Ahmad, S, Ahmed, A, Ahmed, H, Ahmed, S, Akinosoglou, K, Akkaif, M, Akrami, A, Akter, E, Al Awaidy, S, Al Hasan, S, Al Mosa, A, Al Ta'ani, O, Al Zaabi, O, Alahdab, F, Alajlani, M, Al-Ajlouni, Y, Alalalmeh, S, Al-Aly, Z, Alam, K, Alam, N, Alam, T, Alam, Z, Al-amer, R, Alanezi, F, Alanzi, T, Albakri, A, Aldhaleei, W, Aldridge, R, Alemohammad, S, Alemu, Y, Al-Gheethi, A, Al-Hanawi, M, Ali, A, Ali, I, Ali, M, Ali, R, Ali, S, Ali, V, Ali, W, Al-Ibraheem, A, Alicandro, G, Alif, S, Aljunid, S, Alla, F, Almazan, J, Al-Mekhlafi, H, Alqutaibi, A, Alrawashdeh, A, Alrousan, S, Al-Sabah, S, Alsabri, M, Altaany, Z, Al-Tammemi, A, Al-Tawfiq, J, Altirkawi, K, Aluh, D, Alvis-Guzman, N, Al-Wardat, M, Al-Worafi, Y, Aly, H, Alyahya, M, Alzoubi, K, Al-Zyoud, W, Amani, R, Ameyaw, E, Amin, T, Amindarolzarbi, A, Amiri, S, Amirzade-Iranaq, M, Amu, H, Amugsi, D, Ancuceanu, R, Anderlini, D, Anderson, D, Andrade, P, Andrei, C, Andrei, T, Andrews, E, Anil, A, Anil, S, Anoushiravani, A, Antony, C, Antriyandarti, E, Anuoluwa, B, Anvari, S, Anyasodor, A, Appiah, F, Aquilano, M, Arab, J, Arabloo, J, Arafa, E, Arafat, M, Aravkin, A, Ardekani, A, Areda, D, Aregawi, B, Aremu, A, Ariffin, H, Arkew, M, Armani, K, Artamonov, A, Arumugam, A, Asghari-Jafarabadi, M, Ashbaugh, C, Astell-Burt, T, Athari, S, Atorkey, P, Atout, M, Aujayeb, A, Ausloos, M, Awad, H, Awotidebe, A, Ayatollahi, H, Ayuso-Mateos, J, Azadnajafabad, S, Azeez, F, Azevedo, R, Badar, M, Baghdadi, S, Bagheri, M, Bagheri, N, Bai, R, Baker, J, Bako, A, Balakrishnan, S, Balcha, W, Baltatu, O, Barchitta, M, Bardideh, E, Barker-Collo, S, Bärnighausen, T, Barqawi, H, Barteit, S, Basiru, A, Basso, J, Bastan, M, Basu, S, Bauckneht, M, Baune, B, Bayati, M, Bayileyegn, N, Behnoush, A, Behzadi, P, Beiranvand, M, Bello, O, Belo, L, Beloukas, A, Bemanalizadeh, M, Bensenor, I, Benzian, H, Beran, A, Berezvai, Z, Bernstein, R, Bettencourt, P, Beyene, K, Beyene, M, Bhagat, D, Bhagavathula, A, Bhala, N, Bhandari, D, Bharadwaj, R, Bhardwaj, N, Bhardwaj, P, Bhargava, A, Bhaskar, S, Bhat, V, Bhattacharjee, N, Bhatti, G, Bhatti, J, Bhatti, M, Bhuiyan, M, Bisignano, C, Biswas, B, Bjørge, T, Bodolica, V, Bodunrin, A, Bonakdar Hashemi, M, Bora Basara, B, Borhany, H, Bosoka, S, Botero Carvajal, A, Bouaoud, S, Boufous, S, Boxe, C, Boyko, E, Brady, O, Braithwaite, D, Brauer, M, Brazo-Sayavera, J, Brenner, H, Brown, C, Browne, A, Brugha, T, 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Tolulope R, Okati-Aliabad, Hassan, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Olagunju, Andrew T, Olatubi, Matthew Idowu, Oliveira, Gláucia Maria Moraes, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oluwafemi, Yinka Doris, Omar, Hany A, Omer, Goran Latif, Ong, Sokking, Onie, Sandersan, Onwujekwe, Obinna E, Opejin, Abdulahi Opejin, Ordak, Michal, Orish, Verner N, Ortiz, Alberto, Ortiz-Prado, Esteban, Osman, Wael M S, Ostojic, Sergej M, Ostroff, Samuel M, Osuagwu, Uchechukwu Levi, Otoiu, Adrian, Otstavnov, Stanislav S, Ouyahia, Amel, Owolabi, Mayowa O, Oyeyemi, Oyetunde T, Ozair, Ahmad, P A, Mahesh Padukudru, Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pal, Pramod Kumar, Palicz, Tamás, Pan, Feng, Pan, Hai-Feng, Panda-Jonas, Songhomitra, Pandey, Anamika, Pando-Robles, Victoria, Pangaribuan, Helena Ullyartha, Panos, Georgios D, Panos, Leonidas D, Pantazopoulos, Ioannis, Pantea Stoian, Anca Mihaela, Parikh, Romil R, Park, Eun-Kee, Park, Seoyeon, Park, 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Yonemoto, Naohiro, You, Yuyi, Younis, Mustafa Z, Yu, Chuanhua, Yu, Elaine A, Yu, Yong, Yuan, Chun-Wei, Yusuf, Hadiza, Zafar, Uzma, Zafari, Nima, Zahid, Mondal Hasan, Zakham, Fathiah, Zaki, Nazar, Zerfu, Taddese Alemu, Zhang, Haijun, Zhang, Jingya, Zhang, Liqun, Zhang, Yunquan, Zhang, Zhiqiang, Zhao, Xiu-Ju George, Zhao, Yang, Zhao, Zhongyi, Zhong, Chenwen, Zhou, Bolun, Zhou, Juexiao, Zhou, Shangcheng, Zhu, Bin, Zhumagaliuly, Abzal, Zielińska, Magdalena, Zoghi, Ghazal, Zumla, Alimuddin, Zyoud, Sa'ed H, Zyoud, Samer H, Smith, Amanda E, and Murray, Christopher J L
- Published
- 2024
23. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
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- Published
- 2024
24. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
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Bhawna, Gupta, Mohak, Gupta, Rahul, Gupta, Rajat Das, Gupta, Rajeev, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vijai Kumar, Gupta, Vivek Kumar, Habibzadeh, Farrokh, Habibzadeh, Parham, Hadaro, Tesfahun Simon, Hadian, Zahra, Haep, Nils, Haghi-Aminjan, Hamed, Haghmorad, Dariush, Hagins, Hailey, Haile, Demewoz, Hailu, Alemayehu, Hajj Ali, Adel, Halboub, Esam S, Halimi, Aram, Hall, Brian J, Haller, Sebastian, Halwani, Rabih, Hamadeh, Randah R, Hamdy, Nadia M, Hameed, Sajid, Hamidi, Samer, Hammoud, Ahmad, Hanif, Asif, Hanifi, Nasrin, Haq, Zaim Anan, Haque, Md Rabiul, Harapan, Harapan, Hargono, Arief, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Ikramul, Hasan, Mohammad Jahid, Hasan, S M Mahmudul, Hasani, Hamidreza, Hasanian, Mohammad, Hashmeh, Nadim, Hasnain, Md Saquib, Hassan, Amr, Hassan, Ikrama, Hassan Zadeh Tabatabaei, Mahgol Sadat, Hassani, Shokoufeh, Hassanipour, Soheil, Hassankhani, Hadi, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, Hebert, Jeffrey J, Hegazi, Omar E, Hegena, 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Iwagami, Masao, Iwu, Chidozie C D, Iwu-Jaja, Chinwe Juliana, J, Vinothini, Jaafari, Jalil, Jacob, Louis, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jain, Akhil, Jain, Nityanand, Jairoun, Ammar Abdulrahman, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jalilzadeh Yengejeh, Reza, Jamora, Roland Dominic G, Jatau, Abubakar Ibrahim, Javadov, Sabzali, Javaheri, Tahereh, Jayaram, Shubha, Jeganathan, Jayakumar, Jeswani, Bijay Mukesh, Jiang, Heng, Johnson, Catherine O, Jokar, Mohammad, Jomehzadeh, Nabi, Jonas, Jost B, Joo, Tamas, Joseph, Abel, Joseph, Nitin, Joshi, Vivek, Joshua, Charity Ehimwenma, Jozwiak, Jacek Jerzy, Jürisson, Mikk, Kaambwa, Billingsley, Kabir, Ali, Kabir, Zubair, Kadashetti, Vidya, Kahn, Ethan M, Kalani, Rizwan, Kaliyadan, Feroze, Kalra, Sanjay, Kamath, Rajesh, Kanagasabai, Thanigaivelan, Kanchan, Tanuj, Kandel, Himal, Kanmiki, Edmund Wedam, Kanmodi, Kehinde Kazeem, Kansal, Sushil Kumar, Kapner, Daniel John, Kapoor, Neeti, Karagiannidis, Efstratios, Karajizadeh, Mehrdad, Karakasis, Paschalis, Karanth, Shama D, Karaye, Ibraheem M, Karch, André, Karim, Asima, Karimi, Hanie, Karmakar, Shilpi, Kashoo, Faizan Zaffar, Kasraei, Hengameh, Kassahun, Woldeteklehaymanot Dagne, Kassebaum, Nicholas J, Kassel, Molly B, Katikireddi, Srinivasa Vittal, Kauppila, Joonas H, Kawakami, Norito, Kaydi, Neda, Kayode, Gbenga A, Kazemi, Foad, Keiyoro, Peter Njenga, Kemmer, Laura, Kempen, John H, Kerr, Jessica A, Kesse-Guyot, Emmanuelle, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khajuria, Himanshu, Khalaji, Amirmohammad, Khalil, Mariam, Khalilian, Alireza, Khamesipour, Faham, Khan, Asaduzzaman, Khan, M Nuruzzaman, Khan, Maseer, Khan, Mohammad Jobair, Khan, Moien AB, Khanmohammadi, Shaghayegh, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khatib, Mahalaqua Nazli, Khavandegar, Armin, Khayat Kashani, Hamid Reza, Khidri, Feriha Fatima, Khodadoust, Elaheh, Khormali, Moein, Khorrami, Zahra, Khosla, Atulya Aman, Khosrowjerdi, Mahmood, Khreis, Haneen, Khusun, Helda, Kifle, Zemene Demelash, Kim, Kwanghyun, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Knibbs, Luke D, Knudsen, Ann Kristin Skrindo, Koh, David S Q, Kolahi, Ali-Asghar, Kompani, Farzad, Kong, Jianqiu, Koren, Gerbrand, Korja, Miikka, Korshunov, Vladimir Andreevich, Korzh, Oleksii, Kosen, Soewarta, Kothari, Nikhil, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Krishnamoorthy, Vijay, Krishnamoorthy, Yuvaraj, Krishnan, Bindu, Krohn, Kris J, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuddus, Md Abdul, Kuddus, Mohammed, Kugbey, Nuworza, Kuitunen, Ilari, Kulimbet, Mukhtar, Kulkarni, Vishnutheertha, Kumar, Ashish, Kumar, Nithin, Kumar, Vijay, Kundu, Satyajit, Kurmi, Om P, Kusnali, Asep, Kusuma, Dian, Kutluk, Tezer, La Vecchia, Carlo, Ladan, Muhammad Awwal, Laflamme, Lucie, Lahariya, Chandrakant, Lai, Daphne Teck Ching, Lal, Dharmesh Kumar, Lallukka, Tea, Lám, Judit, Lan, Qing, 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Muhammed, Elmehrath, Ahmed O, Elmeligy, Omar Abdelsadek Abdou, Elshaer, Mohammed, Elsohaby, Ibrahim, Emeto, Theophilus I, Esfandiari, Negin, Eshrati, Babak, Eslami, Majid, Esmaeili, Sayed Vahid, Estep, Kara, Etaee, Farshid, Fabin, Natalia, Fagbamigbe, Adeniyi Francis, Fagbule, Omotayo Francis, Fahimi, Saman, Falzone, Luca, Fareed, Mohammad, Farinha, Carla Sofia e Sá, Faris, MoezAlIslam Ezzat Mahmoud, Faris, Pawan Sirwan, Faro, Andre, Fasina, Folorunso Oludayo, Fatehizadeh, Ali, Fauk, Nelsensius Klau, Fazylov, Timur, Feigin, Valery L, Feng, Xiaoqi, Fereshtehnejad, Seyed-Mohammad, Feroze, Abdullah Hamid, Ferrara, Pietro, Ferrari, Alize J, Ferreira, Nuno, Fetensa, Getahun, Feyisa, Bikila Regassa, Filip, Irina, Fischer, Florian, Fitriana, Ida, Flavel, Joanne, Flohr, Carsten, Flood, David, Flor, Luisa S, Foigt, Nataliya A, Folayan, Morenike Oluwatoyin, Force, Lisa M, Fortuna, Daniela, Foschi, Matteo, Franklin, Richard Charles, Freitas, Alberto, Friedman, Sara D, Fux, Blima, G, Sridevi, 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Maria, Hasaballah, Ahmed I, Hasan, Ikramul, Hasan, Mohammad Jahid, Hasan, S M Mahmudul, Hasani, Hamidreza, Hasanian, Mohammad, Hashmeh, Nadim, Hasnain, Md Saquib, Hassan, Amr, Hassan, Ikrama, Hassan Zadeh Tabatabaei, Mahgol Sadat, Hassani, Shokoufeh, Hassanipour, Soheil, Hassankhani, Hadi, Haubold, Johannes, Havmoeller, Rasmus J, Hay, Simon I, Hebert, Jeffrey J, Hegazi, Omar E, Hegena, Tadele Yohannes, Heidari, Golnaz, Heidari, Mohammad, Helfer, Bartosz, Hemmati, Mehdi, Henson, Claire A, Herbert, Molly E, Herteliu, Claudiu, Heuer, Austin, Hezam, Kamal, Hinneh, Thomas Kwadwo, Hiraike, Yuta, Hoan, Nguyen Quoc, Holla, Ramesh, Hon, Julia, Hoque, Mohammad Enamul, Horita, Nobuyuki, Hossain, Sahadat, Hosseini, Seyed Ehsan, Hosseinzadeh, Hassan, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Hoven, Hanno, Hsairi, Mohamed, Hsu, Johnathan M, Hu, Chengxi, Huang, Junjie, Huda, Md Nazmul, Hulland, Erin N, Hultström, Michael, Hushmandi, Kiavash, Hussain, Javid, Hussein, Nawfal R, Huynh, Chantal K, Huynh, Hong-Han, Ibitoye, Segun Emmanuel, Idowu, Oluwatope Olaniyi, Ihler, Audrey L, Ikeda, Nayu, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Imam, Mohammad Tarique, Immurana, Mustapha, Inbaraj, Leeberk Raja, Irham, Lalu Muhammad, Isa, Mustafa Alhaji, Islam, Md Rabiul, Ismail, Faisal, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Iwagami, Masao, Iwu, Chidozie C D, Iwu-Jaja, Chinwe Juliana, J, Vinothini, Jaafari, Jalil, Jacob, Louis, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Jahankhani, Kasra, Jahanmehr, Nader, Jahrami, Haitham, Jain, Akhil, Jain, Nityanand, Jairoun, Ammar Abdulrahman, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jalilzadeh Yengejeh, Reza, Jamora, Roland Dominic G, Jatau, Abubakar Ibrahim, Javadov, Sabzali, Javaheri, Tahereh, Jayaram, Shubha, Jeganathan, Jayakumar, Jeswani, Bijay Mukesh, Jiang, Heng, Johnson, Catherine O, Jokar, Mohammad, Jomehzadeh, Nabi, Jonas, Jost B, Joo, Tamas, Joseph, Abel, Joseph, Nitin, Joshi, 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Khalilian, Alireza, Khamesipour, Faham, Khan, Asaduzzaman, Khan, M Nuruzzaman, Khan, Maseer, Khan, Mohammad Jobair, Khan, Moien AB, Khanmohammadi, Shaghayegh, Khatab, Khaled, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khatib, Mahalaqua Nazli, Khavandegar, Armin, Khayat Kashani, Hamid Reza, Khidri, Feriha Fatima, Khodadoust, Elaheh, Khormali, Moein, Khorrami, Zahra, Khosla, Atulya Aman, Khosrowjerdi, Mahmood, Khreis, Haneen, Khusun, Helda, Kifle, Zemene Demelash, Kim, Kwanghyun, Kim, Min Seo, Kim, Yun Jin, Kimokoti, Ruth W, Kisa, Adnan, Kisa, Sezer, Knibbs, Luke D, Knudsen, Ann Kristin Skrindo, Koh, David S Q, Kolahi, Ali-Asghar, Kompani, Farzad, Kong, Jianqiu, Koren, Gerbrand, Korja, Miikka, Korshunov, Vladimir Andreevich, Korzh, Oleksii, Kosen, Soewarta, Kothari, Nikhil, Koul, Parvaiz A, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Krishnamoorthy, Vijay, Krishnamoorthy, Yuvaraj, Krishnan, Bindu, Krohn, Kris J, Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kuddus, Md 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- Abstract
Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 risk factors in 204 countries and territories and 811 subnational locations, from 1990 to 2021. Methods: The GBD 2021 risk factor analysis used data from 54 561 total distinct sources to produce epidemiological estimates for 88 risk factors and their associated health outcomes for a total of 631 risk–outcome pairs. Pairs were included on the basis of data-driven determination of a risk–outcome association. Age-sex-location-year-specific estimates were generated at global, regional, and national levels. Our approach followed the comparative risk assessment framework predicated on a causal web of hierarchically organised, potentially combinative, modifiable risks. Relative risks (RRs) of a given outcome occurring as a function of risk factor exposure were estimated separately for each risk–outcome pair, and summary exposure values (SEVs), representing risk-weighted exposure prevalence, and theoretical minimum risk exposure levels (TMRELs) were estimated for each risk factor. These estimates were used to calculate the population attributable fraction (PAF; ie, the proportional change in health risk that would occur if exposure to a risk factor were reduced to the TMREL). The product of PAFs and disease burden associated with a given outcome, measured in disability-adjusted life-years (DALYs), yielded measures of attributable burden (ie, the proportion of total disease burden attributable to a particular risk factor or combination of risk factors). Adjustments for mediation were applied to account for relationships involving risk
- Published
- 2024
25. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
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- Abstract
Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are updated routinely with additional data and refined analytical methods. GBD 2021 presents, for the first time, estimates of health loss due to the COVID-19 pandemic. Methods: The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. Data were extracted from vital registration systems, verbal autopsies, censuses, household surveys, disease-specific registries, health service contact data, and other sources. YLDs were calculated by multiplying cause-age-sex-location-year-specific prevalence of sequelae by their respective disability weights, for each disease and injury. YLLs were calculated by multiplying cause-age-sex-location-year-specific deaths by the standard life expectancy at the age that death occurred. DALYs were calculated by summing YLDs and YLLs. HALE estimates were produced using YLDs per capita and age-specific mortality rates by location, age, sex, year, and cause.
- Published
- 2024
26. Feed handling practices, aflatoxin awareness and children's milk consumption in the Sidama region of southern Ethiopia
- Author
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Anato, Anchamo; Headey, Derek; Hirvonen, Kalle; Pokharel, Ashish; Tessema, Masresha; Wu, Felicia; Baye, Kaleab and Anato, Anchamo; Headey, Derek; Hirvonen, Kalle; Pokharel, Ashish; Tessema, Masresha; Wu, Felicia; Baye, Kaleab
- Abstract
Development Strategies and Governance (DSG); Transformation Strategies, Consumption of milk is linked to improved nutrient intake and reduced risk of child malnutrition in low and middle-income countries. However, these benefits are contingent on the safety and quality of the milk. Milk consumption may alleviate the widespread risk of malnutrition in rural Ethiopia, but milk-borne contaminants may also compromise child health. We aimed to: i) identify the types of dairy feeds used, their storage conditions, and potential risk of aflatoxin contamination; ii) assess stakeholders' knowledge about aflatoxin contamination along the value chain; and iii) assess parental practices on feeding milk to infants and young children. This qualitative study was conducted in the Sidama region, southern Ethiopia. In-depth interviews (n = 12) and key-informant interviews (n = 18) were conducted with actors along the dairy value chain. Focus-group discussions were conducted with farmers (9FGD/n = 129) and child caregivers (9FGD/n = 122). Study participants were selected to represent a rural-urban gradient, as well as low- and high- dairy cow holdings. We found that while animal-feed processors and their distribution agents had relatively good knowledge about aflatoxin, farmers and retailers did not. Feed storage conditions were poor. Many respondents linked moldy feeds to animal health but not to human health. Farmers' feed choice was influenced by cost, seasonality, and herd size. Small-holding farmers had limited access to commercial feed. Children's consumption of milk was limited to skim milk, as butter was extracted and sold for income. The high cost of dairy products also led some parents to dilute skim milk with water before feeding children, compromising the nutritional value and safety of the milk. Our findings underscore the need to address the gaps in aflatoxin and food safety knowledge, improve storage conditions, and ensure the availability of quality feed to increase the sector's productivity, but most importantly to protect consumers' healt
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- 2024
27. Children’s cognitive impairment associated with cassava cyanide in Democratic Republic of the Congo: Burden of disease
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Chen, Chen, primary and Wu, Felicia, additional
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- 2024
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28. Foodborne mycotoxins
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Wu, Felicia, primary
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- 2021
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29. Contributors
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Ali, Zulfiqar, primary, Carr, C. Chad, additional, Chapman, Benjamin J., additional, Chittiboyina, Amar G., additional, Danyluk, Michelle, additional, Devleesschauwer, Brecht, additional, DeWaal, Caroline Smith, additional, El-Arabi, Tarek F., additional, Estrada-Garcia, Teresa, additional, Fanning, Séamus, additional, Fiore, Andrew, additional, Fortin, Neal D., additional, Foster, Monique A., additional, Fritz, Curtis L., additional, García, Santos, additional, Garcia-Williams, Amanda G., additional, Gharpure, Radhika, additional, Gopinath, Gopal, additional, Grattan, Lynn M., additional, Griffiths, Mansel W., additional, Grim, Christopher J., additional, Hall, Aron J., additional, Havelaar, Arie, additional, Healy, Jessica M., additional, Heredia, Norma, additional, Jang, Hyein, additional, Jones, Timothy F., additional, Juneja, Vijay K., additional, Karst, Stephanie M., additional, Khan, Ikhlas A., additional, Kienesberger, Sabine, additional, Kilmon, Kelsey A., additional, Kumar, Sanjay, additional, Labbé, Ronald G., additional, Lauer, A.C., additional, Lehner, Angelika, additional, Linton, Richard H., additional, Logan, Naeemah, additional, Lúquez, Carolina, additional, Magalis, Brittany Rife, additional, Marsh, Zachary A., additional, Mattison, Claire P., additional, McSwane, David Z., additional, Moller, Amanda, additional, Montazeri, Naim, additional, Morris, Jr., J. Glenn, additional, Nauta, Maarten, additional, Negrete, Flavia, additional, Nesbakken, Truls, additional, Osman, Ahmed G., additional, Parashar, Umesh D., additional, Perez-Perez, Guillermo Ignacio, additional, Pires, Sara M., additional, Plunkett, David, additional, Quinn, Frederick D., additional, Roberts, Cynthia, additional, Ryser, Elliot T., additional, Salemi, Marco, additional, Salgado-Pabón, Wilmara, additional, Scheffler, Jason D., additional, Singh, Manpreet, additional, Sobel, Jeremy, additional, Stockdale Walden, Heather, additional, Tall, Ben D., additional, Tarr, Phillip I., additional, Tauxe, Robert V., additional, Teshale, Eyasu H., additional, Topalcengiz, Zeynal, additional, Tran, Phuong M., additional, Vinjé, Jan, additional, Vugia, Duc J., additional, Wang, Shu-Hua, additional, Weinstein, Leah, additional, Whitehouse, Chris A., additional, Wikswo, Mary E., additional, Wright, Anita C., additional, and Wu, Felicia, additional
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- 2021
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30. The dry chain: reducing postharvest losses and improving food safety in humid climates
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Bradford, Kent J., primary, Dahal, Peetambar, additional, Van Asbrouck, Johan, additional, Kunusoth, Keshavulu, additional, Bello, Pedro, additional, Thompson, James, additional, and Wu, Felicia, additional
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- 2020
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31. List of contributors
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Bello, Pedro, primary, Bradford, Kent J., additional, Branska, Barbara, additional, Chang, Ching-Cheng, additional, Dahal, Peetambar, additional, Dhaliwal, Harcharan Singh, additional, Dharma, Patria Raffel, additional, Díaz, Ismael, additional, Díaz, Mario, additional, Di Leo, Alessio, additional, Drahokoupil, Marek, additional, Fickers, Patrick, additional, Filimonau, Viachaslau, additional, Gherbin, Adriano, additional, González-Miquel, María, additional, Herrero, Mónica, additional, Hsiao, Hsin-I, additional, Jensen, Jørgen Dejgård, additional, Kaur, Rupinder, additional, Koop, Carina, additional, Kosseva, Maria R., additional, Koutinas, Apostolis, additional, Kumar, Krishan, additional, Kumar, Vinod, additional, Kunusoth, Keshavulu, additional, Laca, Adriana, additional, Laca, Amanda, additional, Ladakis, Dimitrios, additional, Li, Wen-Wei, additional, Lin, Carol Sze Ki, additional, Lin, Zhangnan, additional, Liu, Hongjuan, additional, López-Gómez, J. Pablo, additional, Luk, Hung Sum, additional, Manan, Musalbakri Abdul, additional, Melzoch, Karel, additional, Michailos, Stavros, additional, Michelini, Laura, additional, Ndraha, Nodali, additional, Ong, Khai Lun, additional, Panesar, Parmjit S., additional, Pang, Kin Wai, additional, Panwar, Divyani, additional, Papapostolou, Harris, additional, Patakova, Petra, additional, Paulova, Leona, additional, Principato, Ludovica, additional, Schinkel, Jennifer, additional, Somkun, Po-ngarm, additional, Tang, Yu-Ting, additional, Teuber, Ramona, additional, Thompson, James, additional, Todorova, Ekaterina, additional, Uisan, Kristiadi, additional, Van Asbrouck, Johan, additional, Vlajic, Jelena, additional, Vlysidis, Anestis, additional, Vyas, Pritesh, additional, Webb, Colin, additional, Wilts, Henning, additional, Wu, Felicia, additional, Wu, Pengfei, additional, Yadav, Ajar Nath, additional, Yu, Han-Qing, additional, Zhang, Jianan, additional, and Zhou, Yujie, additional
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- 2020
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32. In Search of a Common European Approach to a Healthy Indoor Environment
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Sigsgaard, Torben and Wu, Felicia
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- 2007
33. Childhood Asthma and Environmental Interventions
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Wu, Felicia and Takaro, Tim K.
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- 2007
34. Improving Indoor Environmental Quality for Public Health: Impediments and Policy Recommendations
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Wu, Felicia, Jacobs, David, Miller, David, and Karol, Meryl H.
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- 2007
35. GE Crops: Balancing Predictions of Promise and Peril
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Wolfenbarger, L. LaReesa, Andow, David A., Hilbeck, Angelika, Nickson, Thomas, Wu, Felicia, Thompson, Paul B., and Ammann, Klaus
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- 2004
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36. The need to revisit ochratoxin A risk in light of diabetes, obesity, and chronic kidney disease prevalence
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Chen, Chen and Wu, Felicia
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- 2017
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37. A risk assessment of dietary Ochratoxin a in the United States
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Mitchell, Nicole J., Chen, Chen, Palumbo, Jeffrey D., Bianchini, Andreia, Cappozzo, Jack, Stratton, Jayne, Ryu, Dojin, and Wu, Felicia
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- 2017
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38. Author Correction: The Impact of Bt Corn on Aflatoxin-Related Insurance Claims in the United States
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Yu, Jina, Hennessy, David A., and Wu, Felicia
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- 2020
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39. The Impact of Bt Corn on Aflatoxin-Related Insurance Claims in the United States
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Yu, Jina, Hennessy, David A., and Wu, Felicia
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- 2020
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40. Foodborne disease outbreaks in flour and flour‐based food products from microbial pathogens in the United States, and their health economic burden.
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Rahman, Rubait, Scharff, Robert L., and Wu, Felicia
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FOODBORNE diseases ,MICROBIAL products ,DISEASE outbreaks ,ESCHERICHIA coli ,MEDICAL care costs ,PAIN management - Abstract
The most comprehensive and inclusive estimates for the economic burden of foodborne illness yield values as high as $97.4 billion USD annually. However, broad incidence and cost estimates have limited use if they cannot be attributed to specific foods, for the purposes of food safety control. In this study, we estimated the economic burden of foodborne illnesses resulting from flour and flour‐based food products in the United States from the years 2001 to 2021. The outbreak, illness burden, and health economic data are combined to generate these estimates. Our model combined outbreak data with published Centers for Disease Control and Prevention multipliers to estimate the annual number of illnesses associated with flour‐borne pathogens. We then integrated illness severity data with an updated economic model that accounts for costs related to medical care, productivity loss, loss of life, along with the quality of life loss that entails pain and suffering. In total, 752 cases and 223 hospitalizations from flour‐related illnesses were reported from 2001 to 2021, with an average of 37.6 cases of reported cases annually. However, the actual number of cases, accounting for underreporting and underdiagnosis, can be as high as 19,440 annually. Pathogens involved in these outbreaks are Salmonella, E. coli O157:H7, and E. coli O121. Our estimates suggest average annual economic losses, including healthy years of life lost, of $108 and $258 million using two alternative models. [ABSTRACT FROM AUTHOR]
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- 2023
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41. Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology
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Male, Denis, Wu, Wenda, Mitchell, Nicole J., Bursian, Steven, Pestka, James J., and Wu, Felicia
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- 2016
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42. Health Burden Associated with Tillage-Related PM2.5 Pollution in the United States, And Mitigation Strategies
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Pokharel, Ashish, primary, Hennessy, David A., additional, and Wu, Felicia, additional
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- 2023
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43. Mycotoxin risks are lower in biotech corn
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Wu, Felicia, primary
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- 2022
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44. Chronic aflatoxin exposure in children living in Bhaktapur, Nepal: Extension of the MAL-ED study
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Mitchell, Nicole J, Riley, Ronald T, Egner, Patricia A, Groopman, John D, and Wu, Felicia
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- 2017
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45. Inland capture fishery contributions to global food security and threats to their future
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Youn, So-Jung, Taylor, William W., Lynch, Abigail J., Cowx, Ian G., Douglas Beard, T., Jr., Bartley, Devin, and Wu, Felicia
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- 2014
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46. Bt Corn’s Reduction of Mycotoxins: Regulatory Decisions and Public Opinion
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Wu, Felicia, Zilberman, David, editor, Just, Richard E., editor, and Alston, Julian M., editor
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- 2006
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47. Aflatoxin M1 in milk does not contribute substantially to global liver cancer incidence
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Saha Turna, Nikita, primary, Havelaar, Arie, additional, Adesogan, Adegbola, additional, and Wu, Felicia, additional
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- 2022
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48. Data-driven methods for imputing national-level incidence in global burden of disease studies/Methodes guidees par les donnees pour imputer l'incidence au niveau national en matiere de charge globale des etudes sur les maladies/Metodos basados en datos de imputacion de la incidencia a nivel nacional en los estudios sobre la carga mundial de la morbilidad
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McDonald, Scott A., Devleesschauwer, Brecht, Speybroeck, Niko, Hens, Niel, Praet, Nicolas, Torgerson, Paul R., Havelaar, Arie H., Wu, Felicia, Tremblay, Marlene, Amene, Ermias W., and Dopfer, Dorte
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Medical research -- Management ,Medicine, Experimental -- Management ,Medical informatics -- Management ,Company business management ,Health - Abstract
Objective To develop transparent and reproducible methods for imputing missing data on disease incidence at national- level for the year 2005. Methods We compared several models for imputing missing country-level incidence rates for two foodborne diseases-- congenital toxoplasmosis and aflatoxin-related hepatocellular carcinoma. Missing values were assumed to be missing at random. Predictor variables were selected using least absolute shrinkage and selection operator regression. We compared the predictive performance of naive extrapolation approaches and Bayesian random and mixed-effects regression models. Leave-one-out cross-validation was used to evaluate model accuracy. Findings The predictive accuracy of the Bayesian mixed-effects models was significantly better than that of the naive extrapolation method for one of the two disease models. However, Bayesian mixed-effects models produced wider prediction intervals for both data sets. Conclusion Several approaches are available for imputing missing data at national level. Strengths of a hierarchical regression approach for this type of task are the ability to derive estimates from other similar countries, transparency, computational efficiency and ease of interpretation. The inclusion of informative covariates may improve model performance, but results should be appraised carefully. Objectif Developper des methodes transparentes et reproductibles pour imputer les donnees manquantes sur l'incidence d'une maladie au niveau national pour l'annee 2005. Methodes Nous avons compare plusieurs modeles pour imputer les taux d'incidence manquants au niveau national pour deux maladies d'origine alimentaire: la toxoplasmose congenitale et le carcinome hepatocellulaire lie a l'aflatoxine. Les valeurs manquantes sont supposees etre manquantes au hasard. Les variables predictives ont ete selectionnees en utilisant la regression LASSO [least absolute shrinkage and selection operator). Nous avons compare la performance predictive des approches d'extrapolation naives et les modeles de regression a effets aleatoires et mixtes bayesiens. La validation croisee <> a ete utilisee pour evaluer la precision du modele. Resultats La precision predictive des modeles des effets mixtes bayesiens etait significativement meilleure que celle de la methode d'extrapolation naive pour l'un des deux modeles de maladie. Cependant, les modeles d'effets mixtes bayesiens ont produit des intervalles de prediction plus larges pour les deux ensembles de donnees. Conclusion Plusieurs approches sont disponibles pour imputer les donnees manquantes au niveau national. Les forces d'une approche de regression hierarchique de ce type de tache sont la capacite de deriver des estimations a partir d'autres pays similaires, la transparence, l'efficacite des calculs et la facilite d'interpretation. L'inclusion de covariables informatives peut ameliorer la performance du modele mais les resultats doivent etre evalues avec prudence. Objetivo Desarrollar metodos transparentes y reproducibles de Imputacion de datos ausentes sobre la incidencia de la morbilidad a nivel nacional para el ano 2005. Metodos Se compararon varios modelos de imputacion de las tasas ausentes de incidencia a nivel nacional para dos enfermedades transmitidas por los alimentos, la toxoplasmosis congenita y el carcinoma hepatocelular relacionado con la aflatoxina. Se considero que los valores ausentes faltaban al azar. Las variables de prediccion se seleccionaron por medio de la contraccion absoluta minima y la regresion del operador de la seleccion. Se comparo el rendimiento predictivo de los enfoques de extrapolacion ingenua y los modelos bayesianos de regresion al azar y de efectos mixtos, y se empleo una validacion cruzada dejando uno fuera para evaluar la exactitud del modelo. Resultados La exactitud predictiva de los modelos bayesianos de efectos mixtos fue significativamente mejor que la del metodo de extrapolacion ingenua para uno de los dos modelos de enfermedad. Sin embargo, los modelos bayesianos de efectos mixtos generaron intervalos de prediccion mas amplios para ambos conjuntos de datos. Conclusion Son numerosos los enfoques disponibles para la imputacion de datos ausentes a nivel nacional. Los puntos fuertes de un enfoque de regresion jerarquica para este tipo de tareas son la capacidad de obtener estimaciones de otros paises similares, la transparencia, la eficiencia informatica y la facilidad de interpretacion. La inclusion de covariables informativas puede mejorar el rendimiento del modelo, aunque se deben evaluar atentamente los resultados., Introduction An essential prerequisite for estimating global disease burden using summary health metrics, such as the disability-adjusted life year, (1) is the availability of national-level data on the incidence or [...]
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- 2015
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49. "Modest doubt is called the beacon of the wise"—Incorporating uncertainty in risk analysis from Shakespeare to today.
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Wu, Felicia and Trump, Benjamin D.
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RISK assessment ,RISK society ,HUMAN behavior ,SCIENTIFIC method - Abstract
"Modest doubt is call'd the beacon of the wise."—William Shakespeare, Troilus and Cressida. Although the character Hector warns his fellow Trojans with this line not to engage in war against the Greeks, Shakespeare's works are replete with characters who do not incorporate modest doubt, or any consideration of uncertainty, in their risk decisions. Perhaps Shakespeare was simply a keen observer of human nature. Although risk science has developed tremendously over the last five decades (and scientific inquiry over five centuries), the human mind still frequently defaults to conviction about certain beliefs, absent sufficient scientific evidence—which has effects not just on individual lives, but on policy decisions that affect many. This perspective provides background on the Shakespearean quote in its literary and historical context. Then, as this quote is the theme of the 2023 Society for Risk Analysis Annual Meeting, we describe how "modest doubt"—incorporating the notion of uncertainty into risk analysis for individual and policy decisions—is still the "beacon of the wise" today. [ABSTRACT FROM AUTHOR]
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- 2023
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50. Mycotoxins were not associated with environmental enteropathy in a cohort of Tanzanian children.
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Chen, Chen, Patil, Crystal L., Mduma, Estomih R., Groopman, John D., Riley, Ronald T., and Wu, Felicia
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MYCOTOXINS ,INTESTINAL diseases ,GROWTH of children ,AFLATOXINS ,BIOMARKERS - Abstract
Enteropathy is a pathophysiological condition characterized by decreased intestinal barrier function and absorption. Past studies have hypothesized that mycotoxins might impair children's growth by causing intestinal enteropathy, including interactions between mycotoxins and pathogens. We investigated the association of two mycotoxins, aflatoxin B1 (AFB1) and fumonisin B1 (FB1), independently and in conjunction with microbial pathogens, with fecal biomarkers of environmental enteropathy in children. As part of a larger MAL‐ED study, 196 children were recruited in Haydom, Tanzania, and followed for the first 36 months of life. The gut inflammation biomarkers myeloperoxidase (MPO), neopterin (NEO), and alpha‐1‐antitrypsin (A1AT) were analyzed in stool samples at 24 months; with mean concentrations 5332.5 ng/L MPO, 807.2 nmol/L NEO, and 0.18 mg/g A1AT. Forty‐eight children were measured for AFB1‐lys, with a mean of 5.30 (95% CI: 3.93‐6.66) pg/mg albumin; and 87 were measured for FB1, with a mean of 1.25 (95% CI: 0.72–1.76) ng/ml urine. Although the pathogens adenovirus and Campylobacter were associated with A1AT (p = 0.049) and NEO (p = 0.004), respectively, no association was observed between aflatoxin (MPO, p = 0.30; NEO, p = 0.08; A1AT, p = 0.24) or fumonisin (MPO, p = 0.38; NEO, p = 0.65; A1AT, p = 0.20) exposure and any gut inflammation biomarkers; nor were interactive effects found between mycotoxins and pathogens in contributing to intestinal enteropathy in this cohort. Although further studies are needed to confirm these results, it is possible that mycotoxins contribute to child growth impairment via mechanisms other than disrupting children's intestinal function. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
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