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42 results on '"Wu, Der-Jinn"'

14. Subaortic-Right Atrial Fistula after Endocarditis in Hypertrophic Cardiomyopathy

Author

Sia, Sung-Kien, Wu, Yi-Liang, Wu, Der-Jinn, Lin, Ming-Cheng, and Ueng, Kwo-Chang

Subjects
Case Report
Abstract

Infective endocarditis in hypertrophic obstructive cardiomyopathy is rare. Management of this disease is challenging due to the unique features of dynamic pressure gradient over the left ventricular outflow tract and its unpredictable interaction with the management of sepsis. The added complexity of infective endocarditis further complicates an already difficult situation.

Published
2013

17. Nicorandil Improves Post-Ischemic Myocardial Dysfunction in Association With Opening the Mitochondrial KATP Channels and Decreasing Hydroxyl Radicals in Isolated Rat Hearts

Author

Lu, Chuanjiang, primary, Minatoguchi, Shinya, additional, Arai, Masazumi, additional, Wang, Ningyuan, additional, Chen, Xue-Hai, additional, Bao, Narentuoya, additional, Kawamura, Itta, additional, Yasuda, Shinji, additional, Kobayashi, Hiroyuki, additional, Wu, Der-Jinn, additional, Takemura, Genzou, additional, and Fujiwara, Hisayoshi, additional

Published
2006
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24. Combination of N-Methyl-1-Deoxynojirimycin and Ischemic Preconditioning Markedly Reduces the Size of Myocardial Infarcts in Rabbits

Author

Wu, Der-Jinn, primary, Minatoguchi, Shinya, additional, Uno, Yoshihiro, additional, Arai, Masazumi, additional, Wang, Ningyuan, additional, Nishida, Yoshio, additional, Hashimoto, Kazuaki, additional, Hashimoto, Yasuko, additional, Takemura, Genzou, additional, Fujiwara, Takako, additional, and Fujiwara, Hisayoshi, additional

Published
2001
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28. Use of enalapril to facilitate sinus rhythm maintenance after external cardioversion of long-standing persistent atrial fibrillation.

Author

Ueng, Kwo-Chang, Tsai, Tsung-Po, Yu, Wen-Chung, Tsai, Chin-Feng, Lin, Ming-Cheng, Chan, Kuei-Chuan, Chen, Chung-Yin, Wu, Der-Jinn, Lin, Chung-Sheng, and Chen, Shih-Ann

Abstract

Aims This study aimed to assess whether enalapril could improve cardioversion outcome and facilitate sinus rhythm maintenance after conversion of chronic atrial fibrillation (AF).Methods and results Patients with chronic AF for more than 3 months were assigned to receive either amiodarone (200mg orally 3 times a day; group I: n=75) or the same dosage of amiodarone plus enalapril (10mg twice a day; group II: n=70) 4 weeks before scheduled external cardioversion. The end-point was the time to first recurrence of AF. In 125 patients (86.2%), AF was converted to sinus rhythm. Group II had a trend to a trend to a lower rate of immediate recurrence of AF than group I did (4.3% vs 14.7%, P=0.067). Kaplan–Meier analysis demonstrated a higher probability of group II remaining in sinus rhythm at 4 weeks (84.3% vs 61.3%, P=0.002) and at the median follow-up period of 270 days (74.3% vs 57.3%, P=0.021) than in group II.Conclusion The addition of enalapril to amiodarone decreased the rate of immediate and subacute arrhythmia recurrences and facilitated subsequent long-term maintenance of sinus rhythm after cardioversion of persistent AF. [ABSTRACT FROM PUBLISHER]

Published
2003
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34. Influence of propranolol on high energy phosphate and tissue acidosis in regional ischemic myocardium of pigs: assessment with arterial pressure and respiration gated in vivo 31-phosphorus magnetic resonance spectroscopy

Author

Tanaka, Masaru, primary, Fujiwara, Hisayoshi, additional, Ishida, Moriharu, additional, Kida, Mitsugu, additional, Onodera, Tomoya, additional, Wu, Der-Jinn, additional, Matsuda, Mitsuo, additional, Kawamura, Atsushi, additional, Takemura, Genzou, additional, Kawai, Chuichi, additional, Yamashita, Shuji, additional, Koga, Keiko, additional, Nakayama, Sunao, additional, Miura, Iwao, additional, and Yabuuchi, Youichi, additional

Published
1989
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37. Acceleration of cell necrosis following reperfusion after ischemia in the pig heart without collateral circulation

Author

Fujiwara, Hisayoshi, primary, Onodera, Tomoya, additional, Tanaka, Masaru, additional, Miyazaki, Shunichi, additional, Wu, Der-Jinn, additional, Matsuda, Mitsuo, additional, Kawamura, Atsushi, additional, Ishida, Moriharu, additional, Takemura, Genzou, additional, Fujiwara, Yasunori, additional, Fujiwara, Takako, additional, and Kawai, Chuichi, additional

Published
1989
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38. Distribution and progression of coronary arterial and aortic lesions in the conventional watanabe heritable hyperlipidemic rabbit. Quantitative analysis.

Author

WU, DER-JINN, primary, FUJIWARA, HISAYOSHI, additional, TANAKA, MASARU, additional, ONODERA, TOMOYA, additional, MATSUDA, MITSUO, additional, ISHIDA, MORIHARU, additional, KAWAMURA, ATSUSHI, additional, TAKEMURA, GENZOU, additional, FUJIWARA, TAKAKO, additional, NAGANO, YUTAKA, additional, ISHII, KENJI, additional, KITA, TORU, additional, KAWAI, CHUICHI, additional, and HAMASHIMA, YOSHIHIRO, additional

Published
1988
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40. Subaortic-Right Atrial Fistula after Endocarditis in Hypertrophic Cardiomyopathy.

Author

Sia SK, Wu YL, Wu DJ, Lin MC, and Ueng KC

Abstract

Unlabelled: Infective endocarditis in hypertrophic obstructive cardiomyopathy is rare. Management of this disease is challenging due to the unique features of dynamic pressure gradient over the left ventricular outflow tract and its unpredictable interaction with the management of sepsis. The added complexity of infective endocarditis further complicates an already difficult situation. A 72-year-old man with hypertrophic obstructive cardiomyopathy presented with acute stroke, fever, and Staphylococcus aureus bacteremia. Infective endocarditis of the aortic valve was confirmed. Despite treatment with antibiotics and aortic valve replacement, the patient had recurrent bacteremia and developed a periannular abscess and a subaortic-right atrial fistula, with a resulting fatal outcome., Key Words: Aortic valve replacement; Endocarditis; Hypertrophic obstructive cardiomyopathy; Subaortic-right atrial fistula.

Published
2013

41. Retrospective evaluation of infective endocarditis over ten years in Taiwan.

Author

Hung HC, Chen SC, Chan KC, Tsui TL, Tsao SM, Leel YT, and Wu DJ

Subjects
Adult, Aged, Aged, 80 and over, Echocardiography, Endocarditis, Bacterial complications, Endocarditis, Bacterial therapy, Female, Gram-Negative Bacterial Infections complications, Gram-Negative Bacterial Infections microbiology, Gram-Negative Bacterial Infections therapy, Gram-Positive Bacterial Infections complications, Gram-Positive Bacterial Infections microbiology, Gram-Positive Bacterial Infections therapy, Hospital Mortality, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Staphylococcal Infections complications, Staphylococcal Infections therapy, Streptococcal Infections complications, Streptococcal Infections therapy, Substance Abuse, Intravenous complications, Taiwan, Treatment Outcome, Endocarditis, Bacterial microbiology, Staphylococcal Infections microbiology, Streptococcal Infections microbiology
Abstract

Background and Aim of the Study: The echocardiographic findings, microbiological profiles, risk factors for mortality, and outcomes of intravenous drug (IVD) users and non-users with infective endocarditis (IE) in Taiwan were evaluated., Methods: In this retrospective study, the charts of IVD users and non-users who were treated for IE between January 1999 and December 2009 in a hospital in Taiwan were reviewed., Results: A total of 108 patients (including 26 IVD users) with definite diagnoses of IE according to the modified Duke criteria were enrolled in the study. Typically, IVD users were significantly more likely to be infected with Staphylococcus aureus (p < 0.001). A greater proportion of IVD users had higher levels of hemoglobin (84.6% versus 62.2%; p = 0.033) and a lower percentage had high platelet counts (42.3% versus 73.2%; p = 0.004) when compared to non-users. A higher percentage of IVD users had hepatitis C compared to non-users (73.1% versus 11%; p < 0.001). Most non-users had vegetations in the mitral and aortic valves (40/74; 54.1% and 35/74; 47.3%, respectively), whereas IVD users had significantly more vegetations in the tricuspid valve (10/18; 55.6%). The overall in-hospital mortality rate was 33.3% (36/108), but the rate for IVD users (11.5%; 3/26) was significantly lower than that for non-users (40.2%; 33/82) (p = 0.007). Multivariate analysis showed that age > 40 years and serum creatinine level > or = 1.2 mg/dl were significantly associated with higher mortality [odds ratios (ORs) 1.06 and 7.49, respectively; p < 0.001 for both]. When the entire patient group was analyzed, a significantly better survival was associated with IVD use and surgical intervention (ORs 0.19 and 0.11; p = 0.012 and 0.011, respectively)., Conclusion: The clinical features, microbiological spectra and outcomes of IVD users with IE were different from those of non-users. Among all patients, a higher age and elevated serum creatinine levels were significant risk factors for mortality, whereas IVD use and surgical intervention were associated with higher rates of survival.

Published
2013

42. Pathological and biochemical analysis of dilated cardiomyopathy of broiler chickens--an animal model.

Author

Wu DJ, Lin JA, Chiu YT, Cheng CC, Shyu CL, Ueng KC, and Huang CY

Subjects
Animals, Ascites pathology, Cold Temperature, Female, Male, Matrix Metalloproteinase 2 metabolism, Matrix Metalloproteinase 9 metabolism, Models, Animal, Myocardium enzymology, Myocardium pathology, Bird Diseases pathology, Cardiomyopathy, Dilated pathology, Chickens
Abstract

Forty-seven birds (M/F = 33/14) with natural outbreak dilated cardiomyopathy (DCM) of right ventricle (RV) and 33 birds with artificially cool-induced DCM hearts were studied. Clinically, 20 severe and 13 mild DCM cases were induced during five weeks and the peak morbidity was in the 2nd week. The progressive dilatation of RV and hypokinesis of septum was shown by echocardiography. At autopsy, the ratio of heart weights to the body weights was increased, the ratio of RV weight to the total ventricle significantly increased, especially in the severe DCM cases (P < 0.05). The RV was dilated and the wall thickness was increased and finally both RV and left ventricle (LV) were markedly dilated and the septum became thinner. The struts, weave and coil demonstrated by silver impregnation stain were fragmented, dissociated and overstretched. The promatrix metalloproteinases (MMP)-2, -9 and active MMP-2 were markedly increased in natural outbreak DCM cases, especially in the RV (P < 0.05). The proMMP-2 and active MMP-2 was increased in the cool induced DCM cases, especially in the RV of severe DCM (P < 0.05). These indicated that both the natural outbreak and the artificially induced DCM of broiler chickens are ideal DCM animal models.

Published
2003

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