364 results on '"Worrall, L."'
Search Results
2. Measuring communication as a core outcome in aphasia trials:Results of the ROMA-2 international core outcome set development meeting
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Wallace, S. J., Worrall, L., Rose, T. A., Alyahya, R. S. W., Babbitt, E., Beeke, S., de Beer, C., Bose, A., Bowen, A., Brady, M. C., Breitenstein, C., Bruehl, S., Bryant, L., Cheng, B. B. Y., Cherney, L. R., Conroy, P., Copland, D. A., Croteau, C., Cruice, M., Dipper, L., Hilari, K., Howe, T., Kelly, H., Kiran, S., Laska, A. C., Marshall, J., Murray, L. L., Patterson, J., Pearl, G., Quinting, J., Rochon, E., Rose, M. L., Rubi-Fessen, I., Sage, K., Simmons-Mackie, N., Visch-Brink, E., Volkmer, A., Webster, J., Whitworth, A., Dorze, G. L., Wallace, S. J., Worrall, L., Rose, T. A., Alyahya, R. S. W., Babbitt, E., Beeke, S., de Beer, C., Bose, A., Bowen, A., Brady, M. C., Breitenstein, C., Bruehl, S., Bryant, L., Cheng, B. B. Y., Cherney, L. R., Conroy, P., Copland, D. A., Croteau, C., Cruice, M., Dipper, L., Hilari, K., Howe, T., Kelly, H., Kiran, S., Laska, A. C., Marshall, J., Murray, L. L., Patterson, J., Pearl, G., Quinting, J., Rochon, E., Rose, M. L., Rubi-Fessen, I., Sage, K., Simmons-Mackie, N., Visch-Brink, E., Volkmer, A., Webster, J., Whitworth, A., and Dorze, G. L.
- Abstract
Background: Evidence-based recommendations for a core outcome set (COS; minimum set of outcomes) for aphasia treatment research have been developed (the Research Outcome Measurement in Aphasia—ROMA, COS). Five recommended core outcome constructs: communication, language, quality of life, emotional well-being and patient-reported satisfaction/impact of treatment, were identified through three international consensus studies. Constructs were paired with outcome measurement instruments (OMIs) during an international consensus meeting (ROMA-1). Before the current study (ROMA-2), agreement had not been reached on OMIs for the constructs of communication or patient-reported satisfaction/impact of treatment. Aim: To establish consensus on a communication OMI for inclusion in the ROMA COS. Methods & Procedures: Research methods were based on recommendations from the Core Outcome Measures in Effectiveness Trials (COMET) Initiative. Participants with expertise in design and conduct of aphasia trials, measurement instrument development/testing and/or communication outcome measurement were recruited through an open call. Before the consensus meeting, participants agreed on a definition of communication, identified appropriate OMIs, extracted their measurement properties and established criteria for their quality assessment. During the consensus meeting they short-listed OMIs and participants without conflicts of interest voted on the two most highly ranked instruments. Consensus was defined a priori as agreement by ≥ 70% of participants. Outcomes & Results: In total, 40 researchers from nine countries participated in ROMA-2 (including four facilitators and three-panel members who participated in pre-meeting activities only). A total of 20 OMIs were identified and evaluated. Eight short-listed communication measures were further evaluated for their measurement properties and ranked. Participants in the consensus meeting (n = 33) who did not have conflicts of interest
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- 2023
3. A survey of speech pathologists' opinions about the prospective acceptability of an online implementation platform for aphasia services.
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Trebilcock, M, Shrubsole, K, Worrall, L, Ryan, B, Trebilcock, M, Shrubsole, K, Worrall, L, and Ryan, B
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BACKGROUND: Online knowledge translation (KT) approaches are becoming increasingly prevalent within healthcare due to their accessibility and facilitation of international support networks. Online platforms enable timely and far-reaching dissemination of current evidence and best-practice recommendations. Although there is potential to improve the uptake of rehabilitation guidelines, it is essential to consider the acceptability of online approaches to healthcare professionals to ensure their successful integration within everyday clinical settings. AIMS: To establish the prospective acceptability of a theoretically informed online intervention for speech pathologists, Aphasia Nexus: Connecting Evidence to Practice, that aims to facilitate the implementation of aphasia best practice. METHODS & PROCEDURES: A mixed-methods multinational electronic survey based on the Theoretical Framework of Acceptability (TFA) completed by aphasia researchers and clinicians. OUTCOMES & RESULTS: A total of 43 participants completed the survey with 91% (n = 39) indicating that they would use Aphasia Nexus. Understanding the intervention and how it works (intervention coherence as per the TFA) was the key factor influencing the likelihood of integration within everyday clinical practice. Participants identified potential areas where the intervention could influence service change and also recommended further design and content changes to improve the intervention. CONCLUSIONS & IMPLICATIONS: Aphasia Nexus is an acceptable platform for further feasibility testing in the form of a pilot trial within an Australian-based health service. The study progresses the theory of TFA as it was a valuable framework facilitating the identification of prominent factors influencing acceptability. The study also informs further intervention refinements in preparation for the next stage of research. WHAT THIS PAPER ADDS: What is already known on the subject Online strategies have the potential to enhance K
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- 2023
4. Experiences of mood changes and preferences for management within stepped psychological care from the perspective of spouses of people with aphasia
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Iwasaki, N, Ryan, B, Worrall, L, Rose, M, Baker, C, Iwasaki, N, Ryan, B, Worrall, L, Rose, M, and Baker, C
- Abstract
Background: Spouses of people with aphasia are at an increased risk of depression and other mood problems. Despite this, there is limited research addressing the experiences and preferences for psychological care of spouses. Aims: To describe, from the perspective of spouses of people with aphasia: (a) the experience of mood changes, depression, and current practice after post-stroke aphasia for themselves and the person with aphasia; and (b) preferences of care within a stepped psychological care framework. Methods: Four spouses of people with aphasia participated in two in-depth, semi-structured interviews each. Eight interviews were transcribed verbatim and analysed using Interpretive Description. Results: Four core themes were identified: (1) Stroke and aphasia results in mood changes for both the spouse and the person with aphasia; (2) Spouses and people with aphasia experience a lack of psychological supports and other services; (3) Relationships with family, friends, health professionals, and the person with aphasia can influence mood in the post-stroke experience; (4) The implementation of stepped psychological care to stroke rehabilitation is important for spouses and people with aphasia. Conclusion: Spouses experienced largely negative impacts of stroke and aphasia on their mood and wellbeing. They held positive views about the need for psychological care and identified various preferences for intervention. Health professionals may consider the preferences of spouses when providing psychological interventions and support.
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- 2023
5. Environmental factors that influence communication for patients with a communication disability in acute hospital stroke units: A qualitative metasynthesis
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O'Halloran, Robyn, Grohn, B, Path, BS, and Worrall, L
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Uncategorized - Abstract
Environmental factors that influence communication for patients with a communication disability in acute hospital stroke units: a qualitative metasynthesis. To develop a taxonomy of the environmental factors that influence communication between patients with communication disabilities and their health care providers in hospital stroke units. We conducted a metasynthesis of 3 qualitative studies conducted by our research team on the environmental factors that influence communication between patients and health care providers in hospital stroke units. These studies identified environmental factors which influence communication from the perspectives of 10 patients with communication disabilities, 10 health care providers, and by direct observation of 65 patients interacting with health care providers. The findings of each study formed the data for the metasynthesis. The findings of the qualitative studies were analyzed and then synthesized using reciprocal translation. The environmental factors were grouped into 11 higher order categories and 2 overall themes. The themes were (1) health care providers (knowledge, skills, attitude, experience, characteristics) and (2) stroke unit structure and processes (patient opportunities to communicate, family, use of communication aids and equipment, opportunities to learn, policies and procedures, physical environment). Acute stroke inpatients with communication disabilities need knowledgeable and skilled health care providers to communicate as effectively as possible. However, there are many environmental barriers and facilitators at the level of stroke unit structures and processes that also impact on the ability of health care providers to communicate with patients. Interventions to improve the communicative accessibility of stroke units need to focus on health care providers and on the processes that govern the unit. © 2012 American Congress of Rehabilitation Medicine.
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- 2023
- Full Text
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6. Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin
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Hu, J., Worrall, L. J., Hong, C., Vuckovic, M., Atkinson, C. E., Caveney, N., Yu, Z., and Strynadka, N. C. J.
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- 2018
- Full Text
- View/download PDF
7. Development of an online implementation intervention for aphasia clinicians to increase the intensity and comprehensiveness of their service.
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Trebilcock, M, Shrubsole, K, Worrall, L, Ryan, B, Trebilcock, M, Shrubsole, K, Worrall, L, and Ryan, B
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PURPOSE: To describe the process and outcome of a user and theory informed online intervention for speech pathologists targeting the implementation of intensive and comprehensive aphasia services. METHODS: The design process followed the eight steps outlined by the Behaviour Change Wheel and incorporated the principles of Integrated Knowledge Translation (IKT). Eight speech pathology researchers and clinicians from four countries (Australia, Canada, the United Kingdom and Ireland) contributed to three focus groups via videoconference. RESULTS: The online platform, Aphasia Nexus: Connecting Evidence to Practice, provides resources, guidance and support for speech pathologists seeking to improve the intensity and comprehensiveness of their aphasia service. A collaborative and iterative design process facilitated the creation of an intervention envisioned by participants. CONCLUSIONS: The website contains both interactive elements and resource links which have been arranged under the three headings of resources, action and support. The inclusion of multi-national researchers and clinicians benefitted a design process to make implementation more likely.IMPLICATIONS FOR REHABILITATIONTheoretically informed implementation interventions aim to change the everyday clinical practice of health workers.An online platform has been developed to support speech pathologists' implementation of intensive and comprehensive aphasia services.A collaborative design process can be beneficial in creating an intervention that is relevant to research-users and is more likely to be implemented.
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- 2022
8. Precision rehabilitation for aphasia by patient age, sex, aphasia severity, and time since stroke? A prespecified, systematic review-based, individual participant data, network, subgroup meta-analysis
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The RELEASE Collaborators, T., Brady, M.C., Ali, M, Ruiter, M.B., Worrall, L., Harris Wright, H., The RELEASE Collaborators, T., Brady, M.C., Ali, M, Ruiter, M.B., Worrall, L., and Harris Wright, H.
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14 mei 2022, Item does not contain fulltext
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- 2022
9. Dosage, Intensity, and Frequency of Language Therapy for Aphasia. A Systematic Review. Based, Individual Participant Data Network Meta-Analysis
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Brady, M.C., Myzoon, A., Vandenberg, K., Ruiter, M.B., Worrall, L., Haris Wright, H., Brady, M.C., Myzoon, A., Vandenberg, K., Ruiter, M.B., Worrall, L., and Haris Wright, H.
- Abstract
01 december 2021, Contains fulltext : 244592.pdf (Publisher’s version ) (Open Access)
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- 2022
10. Measuring communication as a core outcome in aphasia trials: Results of the ROMA-2 international core outcome set development meeting.
- Author
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Wallace, SJ, Worrall, L, Rose, TA, Alyahya, RSW, Babbitt, E, Beeke, S, de Beer, C, Bose, A, Bowen, A, Brady, MC, Breitenstein, C, Bruehl, S, Bryant, L, Cheng, BBY, Cherney, LR, Conroy, P, Copland, DA, Croteau, C, Cruice, M, Dipper, L, Hilari, K, Howe, T, Kelly, H, Kiran, S, Laska, A-C, Marshall, J, Murray, LL, Patterson, J, Pearl, G, Quinting, J, Rochon, E, Rose, ML, Rubi-Fessen, I, Sage, K, Simmons-Mackie, N, Visch-Brink, E, Volkmer, A, Webster, J, Whitworth, A, Dorze, GL, Wallace, SJ, Worrall, L, Rose, TA, Alyahya, RSW, Babbitt, E, Beeke, S, de Beer, C, Bose, A, Bowen, A, Brady, MC, Breitenstein, C, Bruehl, S, Bryant, L, Cheng, BBY, Cherney, LR, Conroy, P, Copland, DA, Croteau, C, Cruice, M, Dipper, L, Hilari, K, Howe, T, Kelly, H, Kiran, S, Laska, A-C, Marshall, J, Murray, LL, Patterson, J, Pearl, G, Quinting, J, Rochon, E, Rose, ML, Rubi-Fessen, I, Sage, K, Simmons-Mackie, N, Visch-Brink, E, Volkmer, A, Webster, J, Whitworth, A, and Dorze, GL
- Abstract
BACKGROUND: Evidence-based recommendations for a core outcome set (COS; minimum set of outcomes) for aphasia treatment research have been developed (the Research Outcome Measurement in Aphasia-ROMA, COS). Five recommended core outcome constructs: communication, language, quality of life, emotional well-being and patient-reported satisfaction/impact of treatment, were identified through three international consensus studies. Constructs were paired with outcome measurement instruments (OMIs) during an international consensus meeting (ROMA-1). Before the current study (ROMA-2), agreement had not been reached on OMIs for the constructs of communication or patient-reported satisfaction/impact of treatment. AIM: To establish consensus on a communication OMI for inclusion in the ROMA COS. METHODS & PROCEDURES: Research methods were based on recommendations from the Core Outcome Measures in Effectiveness Trials (COMET) Initiative. Participants with expertise in design and conduct of aphasia trials, measurement instrument development/testing and/or communication outcome measurement were recruited through an open call. Before the consensus meeting, participants agreed on a definition of communication, identified appropriate OMIs, extracted their measurement properties and established criteria for their quality assessment. During the consensus meeting they short-listed OMIs and participants without conflicts of interest voted on the two most highly ranked instruments. Consensus was defined a priori as agreement by ≥ 70% of participants. OUTCOMES & RESULTS: In total, 40 researchers from nine countries participated in ROMA-2 (including four facilitators and three-panel members who participated in pre-meeting activities only). A total of 20 OMIs were identified and evaluated. Eight short-listed communication measures were further evaluated for their measurement properties and ranked. Participants in the consensus meeting (n = 33) who did not have conflicts of interest (n = 29) vo
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- 2022
11. Precision rehabilitation for aphasia by patient age, sex, aphasia severity, and time since stroke? A prespecified, systematic review-based, individual participant data, network, subgroup meta-analysis
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Brady, M. C., Ali, M., VandenBerg, K., Williams, L. J., Williams, L. R., Abo, M., Becker, F., Bowen, A., Brandenburg, C., Breitenstein, C., Bruehl, S., Copland, D. A., Cranfill, T. B., di Pietro-Bachmann, M., Enderby, P., Fillingham, J., Galli, F. L., Gandolfi, M., Glize, B., Godecke, E., Hawkins, N., Hilari, K., Hinckley, J., Horton, S., Howard, D., Jaecks, P., Jefferies, E., Jesus, L.M.T., Kambanaros, M., Kang, E. K., Khedr, E. M., Kong, A. P., Kukkonen, T., Laganaro, M., Ralph, M. L., Laska, A., Leemann, B., Leff, A. P., Lima, R. R., Lorenz, A., MacWhinney, B., Marshall, R. S., Mattioli, F., Mavis, I., Meinzer, M., Nilipour, R., Noe, E., Paik, N-J., Palmer, R., Papathanasiou, I., Patrício, B., Martins, I., Price, C., Jakovac, T. P., Rochon, E., Rose, M. L., Rosso, C., Rubi-Fessen, I., Ruiter, M. B., Snell, C., Stahl, B., Szaflarski, J. P., Thomas, S. A, van de Sandt-Koenderman, M., van der Meulen, I., Visch-Brink, E., Worrall, L., Wright, H. H., and RELEASE Collaboration
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Male ,genetic structures ,Speech Therapy ,Medical and Health Sciences ,rehabilitation ,Language and Speech, Learning and Therapy ,Aphasia ,Humans ,individual ,network meta-analysis ,Aged ,Language ,Infant, Newborn ,Stroke Rehabilitation ,speech and language therapy ,participant data ,Language & Communication ,P1 ,Aphasia/rehabilitation ,Stroke ,aphasia ,individual participant data ,Neurology ,Female ,Speech Therapy/methods ,RC ,Stroke/complications - Abstract
Background: Stroke rehabilitation interventions are routinely personalized to address individuals’ needs, goals, and challenges based on evidence from aggregated randomized controlled trials (RCT) data and meta-syntheses. Individual participant data (IPD) meta-analyses may better inform the development of precision rehabilitation approaches, quantifying treatment responses while adjusting for confounders and reducing ecological bias. Aim: We explored associations between speech and language therapy (SLT) interventions frequency (days/week), intensity (h/week), and dosage (total SLT-hours) and language outcomes for different age, sex, aphasia severity, and chronicity subgroups by undertaking prespecified subgroup network meta-analyses of the RELEASE database. Methods: MEDLINE, EMBASE, and trial registrations were systematically searched (inception-Sept2015) for RCTs, including ⩾ 10 IPD on stroke-related aphasia. We extracted demographic, stroke, aphasia, SLT, and risk of bias data. Overall-language ability, auditory comprehension, and functional communication outcomes were standardized. A one-stage, random effects, network meta-analysis approach filtered IPD into a single optimal model, examining SLT regimen and language recovery from baseline to first post-intervention follow-up, adjusting for covariates identified a-priori. Data were dichotomized by age (⩽/> 65 years), aphasia severity (mild–moderate/ moderate–severe based on language outcomes’ median value), chronicity (⩽/> 3 months), and sex subgroups. We reported estimates of means and 95% confidence intervals. Where relative variance was high (> 50%), results were reported for completeness. Results: 959 IPD (25 RCTs) were analyzed. For working-age participants, greatest language gains from baseline occurred alongside moderate to high-intensity SLT (functional communication 3-to-4 h/week; overall-language and comprehension > 9 h/week); older participants’ greatest gains occurred alongside low-intensity SLT (⩽ 2 h/week) except for auditory comprehension (> 9 h/week). For both age-groups, SLT-frequency and dosage associated with best language gains were similar. Participants ⩽ 3 months post-onset demonstrated greatest overall-language gains for SLT at low intensity/moderate dosage (⩽ 2 SLT-h/week; 20-to-50 h); for those > 3 months, post-stroke greatest gains were associated with moderate-intensity/high-dosage SLT (3–4 SLT-h/week; ⩾ 50 hours). For moderate–severe participants, 4 SLT-days/week conferred the greatest language gains across outcomes, with auditory comprehension gains only observed for ⩾ 4 SLT-days/week; mild–moderate participants’ greatest functional communication gains were associated with similar frequency (⩾ 4 SLT-days/week) and greatest overall-language gains with higher frequency SLT (⩾ 6 days/weekly). Males’ greatest gains were associated with SLT of moderate (functional communication; 3-to-4 h/weekly) or high intensity (overall-language and auditory comprehension; (> 9 h/weekly) compared to females for whom the greatest gains were associated with lower-intensity SLT ( 9 h over ⩾ 4 days/week. Conclusions: We observed a treatment response in most subgroups’ overall-language, auditory comprehension, and functional communication language gains. For some, the maximum treatment response varied in association with different SLT-frequency, intensity, and dosage. Where differences were observed, working-aged, chronic, mild–moderate, and male subgroups experienced their greatest language gains alongside high-frequency/intensity SLT. In contrast, older, moderate–severely impaired, and female subgroups within 3 months of aphasia onset made their greatest gains for lower-intensity SLT. The acceptability, clinical, and cost effectiveness of precision aphasia rehabilitation approaches based on age, sex, aphasia severity, and chronicity should be evaluated in future clinical RCTs.
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- 2022
12. RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia
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Brady, MC, Ali, M, VandenBerg, K, Williams, LJ, Williams, LR, Abo, M, Becker, F, Bowen, A, Brandenburg, C, Breitenstein, C, Bruehl, S, Copland, DA, Cranfill, TB, Pietro-Bachmann, MD, Enderby, P, Fillingham, J, Galli, FL, Gandolfi, M, Glize, B, Godecke, E, Hawkins, N, Hilari, K, Hinckley, J, Horton, S, Howard, D, Jaecks, P, Jefferies, E, Jesus, LMT, Kambanaros, M, Kang, EK, Khedr, EM, Kong, APH, Kukkonen, T, Laganaro, M, Ralph, MAL, Laska, AC, Leemann, B, Leff, AP, Lima, RR, Lorenz, A, MacWhinney, B, Marshall, RS, Mattioli, F, Maviş, İ, Meinzer, M, Nilipour, R, Noé, E, Paik, NJ, Palmer, R, Papathanasiou, I, Patricio, BF, Martins, IP, Price, C, Jakovac, TP, Rochon, E, Rose, ML, Rosso, C, Rubi-Fessen, I, Ruiter, MB, Snell, C, Stahl, B, Szaflarski, JP, Thomas, SA, Van De Sandt-Koenderman, M, Van Der Meulen, I, Visch-Brink, E, Worrall, L, Wright, HH, Brady, MC [0000-0002-4589-7021], Ali, M [0000-0001-5899-2485], VandenBerg, K [0000-0001-5035-9650], Williams, LJ [0000-0002-6317-1718], Williams, LR [0000-0003-2430-1142], Abo, M [0000-0001-6701-4974], Becker, F [0000-0002-0857-0628], Bowen, A [0000-0003-4075-1215], Brandenburg, C [0000-0002-6992-7790], Breitenstein, C [0000-0002-6408-873X], Bruehl, S [0000-0003-4826-1990], Copland, DA [0000-0002-2257-4270], Cranfill, TB [0000-0001-7608-6443], Pietro-Bachmann, MD [0000-0001-8027-2337], Enderby, P [0000-0002-4371-9053], Fillingham, J [0000-0002-0363-8021], Galli, FL [0000-0001-9244-9179], Gandolfi, M [0000-0002-0877-4807], Glize, B [0000-0001-9618-2088], Hawkins, N [0000-0002-7210-1295], Hilari, K [0000-0003-2091-4849], Hinckley, J [0000-0002-4052-1420], Horton, S [0000-0002-2133-1410], Howard, D [0000-0001-9141-5751], Jaecks, P [0000-0002-5878-1327], Jefferies, E [0000-0002-3826-4330], Jesus, LMT [0000-0002-8534-3218], Kambanaros, M [0000-0002-5857-9460], Kang, EK [0000-0001-5315-1361], Khedr, EM [0000-0001-5679-9833], Kong, APH [0000-0002-6211-0358], Kukkonen, T [0000-0002-8189-0337], Laganaro, M [0000-0002-4054-0939], Ralph, MAL [0000-0001-5907-2488], Laska, AC [0000-0002-7330-940X], Leemann, B [0000-0003-2226-6777], Leff, AP [0000-0002-0831-3541], Lima, RR [0000-0002-9914-4789], Lorenz, A [0000-0002-0200-1977], MacWhinney, B [0000-0002-4988-1342], Marshall, RS [0000-0001-9313-5454], Mattioli, F [0000-0002-4912-5520], Maviş, İ [0000-0003-3924-1138], Meinzer, M [0000-0003-1370-3947], Nilipour, R [0000-0003-4180-7989], Noé, E [0000-0002-2547-8727], Paik, NJ [0000-0002-5193-8678], Palmer, R [0000-0002-2335-7104], Papathanasiou, I [0000-0003-0999-696X], Patricio, BF [0000-0002-2619-470X], Martins, IP [0000-0002-9611-7400], Price, C [0000-0003-0111-9364], Jakovac, TP [0000-0002-5018-9556], Rochon, E [0000-0001-5521-0513], Rose, ML [0000-0002-8892-0965], Rosso, C [0000-0001-7236-1508], Rubi-Fessen, I [0000-0002-9775-3812], Ruiter, MB [0000-0001-6147-5235], Snell, C [0000-0001-8606-7801], Stahl, B [0000-0003-3957-1495], Szaflarski, JP [0000-0002-5936-6627], Thomas, SA [0000-0003-0704-9387], van de Sandt-Koenderman, M [0000-0002-8104-6937], van der Meulen, I [0000-0002-6156-3873], Visch-Brink, E [0000-0001-7833-0112], Worrall, L [0000-0002-3283-7038], Wright, HH [0000-0001-6922-6364], and Apollo - University of Cambridge Repository
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Stroke ,IPD ,meta-analysis ,stroke, aphasia, complex intervention, IPD, meta-analysis ,genetic structures ,aphasia ,complex intervention - Abstract
Background: Speech and language therapy (SLT) benefits people with aphasia following stroke. Group level summary statistics from randomised controlled trials hinder exploration of highly complex SLT interventions and a clinically relevant heterogeneous population. Creating a database of individual participant data (IPD) for people with aphasia aims to allow exploration of individual and therapy-related predictors of recovery and prognosis.\ud \ud Aim: To explore the contribution that individual participant characteristics (including stroke and aphasia profiles) and SLT intervention components make to language recovery following stroke.\ud \ud Methods and procedures: We will identify eligible IPD datasets (including randomised controlled trials, non-randomised comparison studies, observational studies and registries) and invite their contribution to the database. Where possible, we will use meta- and network meta-analysis to explore language performance after stroke and predictors of recovery as it relates to participants who had no SLT, historical SLT or SLT in the primary research study. We will also examine the components of effective SLT interventions.\ud \ud Outcomes and results: Outcomes include changes in measures of functional communication, overall severity of language impairment, auditory comprehension, spoken language (including naming), reading and writing from baseline. Data captured on assessment tools will be collated and transformed to a standardised measure for each of the outcome domains.\ud \ud Conclusion: Our planned systematic-review-based IPD meta- and network meta-analysis is a large scale, international, multidisciplinary and methodologically complex endeavour. It will enable hypotheses to be generated and tested to optimise and inform development of interventions for people with aphasia after stroke.\ud \ud Systematic review registration: The protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42018110947)
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- 2020
13. Predictors of Poststroke Aphasia Recovery
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Ali, M., VandenBerg, K., Williams, L., Abo, M., Becker, F., Bowen, A., Brandenburg, C., Breitenstein, C., Bruehl, S., Copland, D., Cranfill, T. B., Pietro-Bachmann, M. di, Enderby, P., Fillingham, J., Lucia Galli, F., Gandolfi, M., Glize, B., Godecke, E., Hawkins, N., Hilari, K., Hinckley, J., Horton, S., Howard, D., Jaecks, P., Jefferies, E., Jesus, L.M.T., Kambanaros, M., Kyoung Kang, E., Khedr, E. M., Pak-Hin Kong, A., Kukkonen, T., Laganaro, M., Lambon Ralph, M. A., Charlotte Laska, A., Leemann, B., Leff, A., Lima, R., Lorenz, A., Mac Whinney, B., Shisler Marshall, R., Mattioli, F., Mavis, I., Meinzer, M., Nilipour, R., Noe, E., Paik, N-J., Palmer, R., Papathanasiou, I., Patrício, B., Pavao Martins, I., Price, C., Prizl Jakovac, T., Rochon, E., Rose, M., Rosso, C., Rubi-Fessen, I., Ruiter, M. B., Snell, C., Stahl, B., Szaflarski, J. P., Thomas, S. A, van de Sandt-Koenderman, M., van der Meulen, I., Visch-Brink, E., Worrall, L., Harris Wright, H., and Brady, M. C.
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behavioral disciplines and activities ,P1 ,RC - Abstract
Background and Purpose:\ud The factors associated with recovery of language domains after stroke remain uncertain. We described recovery of overall-language-ability, auditory comprehension, naming, and functional-communication across participants’ age, sex, and aphasia chronicity in a large, multilingual, international aphasia dataset.\ud \ud Methods:\ud Individual participant data meta-analysis of systematically sourced aphasia datasets described overall-language ability using the Western Aphasia Battery Aphasia-Quotient; auditory comprehension by Aachen Aphasia Test (AAT) Token Test; naming by Boston Naming Test and functional-communication by AAT Spontaneous-Speech Communication subscale. Multivariable analyses regressed absolute score-changes from baseline across language domains onto covariates identified a priori in randomized controlled trials and all study types. Change-from-baseline scores were presented as estimates of means and 95% CIs. Heterogeneity was described using relative variance. Risk of bias was considered at dataset and meta-analysis level.\ud \ud Results:\ud Assessments at baseline (median=43.6 weeks poststroke; interquartile range [4–165.1]) and first-follow-up (median=10 weeks from baseline; interquartile range [3–26]) were available for n=943 on overall-language ability, n=1056 on auditory comprehension, n=791 on naming and n=974 on functional-communication. Younger age (
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- 2021
14. Stroke health professionals' management of depression after post-stroke aphasia: a qualitative study
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Baker, C, Worrall, L, Rose, M, and Ryan, B
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Stroke ,Depression ,education ,Rehabilitation ,Aphasia ,Stroke Rehabilitation ,Humans ,behavioral disciplines and activities ,11 Medical and Health Sciences ,Qualitative Research - Abstract
Background: People with post-stroke aphasia commonly experience mental health conditions, with depression having a high prevalence. An understanding of current practice may inform ways to improve psychological care for people with aphasia.Aim: To explore current practice for managing depression after post-stroke aphasia from the perspective of stroke health professionals.Method: Five semi-structured focus groups were conducted with 39 stroke health professionals across the care continuum. Focus groups were transcribed verbatim and analyzed using the method of Interpretive Description.Results: Analysis of verbatim transcripts revealed four core themes: (1) concomitant aphasia and depression after stroke is a challenging area of rehabilitation, (2) mood difficulties and depression are not always a high stroke rehabilitation priority, (3) approaches to identification and management are ad hoc, and (4) stroke health professionals are trying to bridge the gap between clients' psychological care needs and limited services. Sub-themes were also identified.Conclusion: This study demonstrates that health professionals are challenged by and limited in managing depression after post-stroke aphasia. Health professionals have the opportunity to improve services through the translation of evidence-based interventions. The integration of mental health care into stroke rehabilitation may be achieved through policy development, leadership and specialist training.Implications for rehabilitationPeople with aphasia need routine mood screening using aphasia-specific clinical tools and communication support.Stroke health professionals report a need for communication partner training to facilitate mental healthcare for people with aphasia.Family members need to be involved in aphasia rehabilitation to gain psychological care for themselves and the person with aphasia.
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- 2021
15. Dosage, Intensity, and Frequency of Language Therapy for Aphasia. A Systematic Review. Based, Individual Participant Data Network Meta-Analysis
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Brady, M.C., Myzoon, A., Vandenberg, K., Ruiter, M.B., Worrall, L., Haris Wright, H., Brady, M.C., Myzoon, A., Vandenberg, K., Ruiter, M.B., Worrall, L., and Haris Wright, H.
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01 december 2021, Item does not contain fulltext
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- 2021
16. Predictors of Poststroke Aphasia Recovery. A Systematic Review-Informed Individual Participant Data Meta-Analysis
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Myzoon, A., Vandenberg, K., Williams, L.J., Williams, L.R., Ruiter, M.B., Worrall, L., Wright, H.H., Brady, M.C., Myzoon, A., Vandenberg, K., Williams, L.J., Williams, L.R., Ruiter, M.B., Worrall, L., Wright, H.H., and Brady, M.C.
- Abstract
Contains fulltext : 233086.pdf (Publisher’s version ) (Open Access)
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- 2021
17. Barriers and facilitators to implementing stepped psychological care for people with aphasia: Perspectives of stroke health professionals.
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Baker, C, Rose, ML, Ryan, B, Worrall, L, Baker, C, Rose, ML, Ryan, B, and Worrall, L
- Abstract
Background Concomitant aphasia and depression after stroke is highly prevalent, but there is a lack of psychological care in stroke rehabilitation for people with aphasia and family members. Evidence-based frameworks such as stepped psychological care may be viable, but the barriers and facilitators to translating this framework into aphasia rehabilitation practice are unknown. Aim The aim of this study was to identify, from the perspective of stroke health professionals, the barriers and facilitators to implementing stepped psychological care for depression after post-stroke aphasia. Method Five semi-structured focus groups of stroke health professionals were conducted (n = 39) across the stroke care continuum. Verbatim transcripts were analyzed using Interpretive Description. Results Barriers and facilitators were identified within three core themes: knowledge, skills, and attitudes have the most impact on implementing stepped psychological care; the physical environment impacts on managing depression and communication disability for people with aphasia; and the support and leadership of the health organization influence change in any implementation of a stepped psychological care approach. Barriers included: no experience with stepped psychological care; limited understanding of aphasia and communication support; lack of adequate physical space and resources; lack of psychologists. Facilitators included: specialist training; enhancement of physical spaces; communication tools; leadership; funding; specialized staff. Conclusion Addressing the identified barriers and facilitators to stepped psychological care will improve the viability of implementing this evidence-based framework after post-stroke aphasia. Change may be driven through specialist training for health professionals in communication support; mood assessment and treatments; modification of physical space; and accessible resources.
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- 2021
18. Cenozoic Eucla Basin and associated palaeovalleys, southern Australia — Climatic and tectonic influences on landscape evolution, sedimentation and heavy mineral accumulation
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Hou, B., Frakes, L.A., Sandiford, M., Worrall, L., Keeling, J., and Alley, N.F.
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- 2008
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19. Investigating the role of intensity in a comprehensive, aphasia therapy program: A non-intensive trial of Aphasia LIFT
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Dignam, J, Rodriguez, A, Burfein, P, OBrien, K, Worrall, L, and Copland, D A
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- 2014
20. The development and validation of Australian aphasia rehabilitation best practice statements
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Power, E, Thomas, E, Worrall, L, Rose, M, and Togher, L
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- 2014
21. RELEASE. Communicating simply, but not too simply. Reporting of participants and speech and language interventions for aphasia after stroke
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Brady, M. C., Ali, M., VandenBerg, K., Williams, L. J., Williams, L., Abo, M., Becker, F., Bowen, A., Brandenburg, C., Breitenstein, C., Bruehl, S., Copland, D., Cranfill, T. B., di Pietro-Bachmann, M., Enderby, P., Fillingham, J., Galli, F., Gandolfi, M., Glize, B., Godecke, E., Hawkins, N., Hilari, K., Hinckley, J., Horton, S., Howard, D., Jaecks, P., Jefferies, E., Jesus, L.M.T., Kambanaros, M., Kang, E. K., Khedr, E. M., Kong, A. P., Kukkonen, T., Laganaro, M., Lambon-Ralph, M. A., Laska, A., Leemann, B., Leff, A. P., Lima, R. R., Lorenz, A., MacWhinney, B., Marshall, R. S., Mattioli, F., Mavis, I., Meinzer, M., Nilipour, R., Noe, E., Paik, N-J., Palmer, R., Papathanasiou, I., Patrício, B., Martins, I., Price, C., Jakovac, T. P., Rochon, E., Rose, M., Rosso, C., Rubi-Fessen, I., Ruiter, M. B., Snell, C., Stahl, B., Szaflarski, J. P., Thomas, S. A., van de Sandt-Koenderman, M., van der Meulen, I., Visch-Brink, E., Worrall, L., Wright, H. H., Tampere University, Department of Neurosciences and Rehabilitation, Welfare Sciences, and RELEASE Collaboration
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medicine.medical_specialty ,Speech-Language Pathology ,515 Psychology ,Applied psychology ,Psychological intervention ,Context (language use) ,Language and Linguistics ,3124 Neurology and psychiatry ,Language and Speech, Learning and Therapy ,Speech and Hearing ,complex interventions ,Intervention (counseling) ,Aphasia ,medicine ,Humans ,Uncategorized ,Research and Theory ,Stroke Rehabilitation ,Secondary data ,speech and language therapy ,Guideline ,LPN and LVN ,stroke ,Checklist ,aphasia ,Language & Communication ,P1 ,Stroke ,Otorhinolaryngology ,medicine.symptom ,Psychology ,RC - Abstract
© 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Purpose: Speech and language pathology (SLP) for aphasia is a complex intervention delivered to a heterogeneous population within diverse settings. Simplistic descriptions of participants and interventions in research hinder replication, interpretation of results, guideline and research developments through secondary data analyses. This study aimed to describe the availability of participant and intervention descriptors in existing aphasia research datasets. Method: We systematically identified aphasia research datasets containing ≥10 participants with information on time since stroke and language ability. We extracted participant and SLP intervention descriptions and considered the availability of data compared to historical and current reporting standards. We developed an extension to the Template for Intervention Description and Replication checklist to support meaningful classification and synthesis of the SLP interventions to support secondary data analysis. Result: Of 11, 314 identified records we screened 1131 full texts and received 75 dataset contributions. We extracted data from 99 additional public domain datasets. Participant age (97.1%) and sex (90.8%) were commonly available. Prior stroke (25.8%), living context (12.1%) and socio-economic status (2.3%) were rarely available. Therapy impairment target, frequency and duration were most commonly available but predominately described at group level. Home practice (46.3%) and tailoring (functional relevance 46.3%) were inconsistently available. Conclusion : Gaps in the availability of participant and intervention details were significant, hampering clinical implementation of evidence into practice and development of our field of research. Improvements in the quality and consistency of participant and intervention data reported in aphasia research are required to maximise clinical implementation, replication in research and the generation of insights from secondary data analysis. Systematic review registration: PROSPERO CRD42018110947.
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- 2020
22. ‘It was really dark’: the experiences and preferences of people with aphasia to manage mood changes and depression
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Baker, C, Worrall, L, Rose, M, Ryan, B, Baker, C, Worrall, L, Rose, M, and Ryan, B
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© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Background: People with aphasia are at high risk of depression with the majority fulfilling depression diagnostic criteria up to one year post-stroke. There is a lack of psychological care to prevent and treat depression and address the communication disability associated with aphasia. Translating a framework of stepped psychological care after stroke may potentially address treatment gaps and improve rehabilitation outcomes. This multidisciplinary framework is usually composed of level 1 to 4 interventions that match the person’s level of need and severity of symptoms. However, the perspectives of people with aphasia regarding stepped psychological care, mood changes, depression and current practice is extremely limited in the research evidence. Aims: To describe, from the perspective of people with aphasia: a) the experience of mood changes, depression and current practice after post-stroke aphasia; and b) preferences within a stepped psychological care approach. Method & Procedures: Ten people with aphasia participated in two semi-structured interviews each, within a maximal variation sample (severity of aphasia, presence or not of possible depression, transition phase of care). Video data from the 20 interviews were transcribed for speech and non-speech communication and analysed using Interpretive Description. Outcomes & Results: All participants self-reported mostly negative mood changes after aphasia whether they were identified as depressed or not on the SADQ10. Three core themes were derived: 1) the onset of stroke and aphasia is a traumatic event resulting in mood difficulties and depression; 2) people with aphasia are trying to work through communication and mood difficulties with limited psychological support and services in stroke rehabilitation; 3) positivity, supported communication and access to individually tailored therapy would be essential to people with aphasia through stepped
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- 2020
23. Time to step up: A call for the speech pathology1 profession to utilise stepped psychological care for people with aphasia post stroke
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Brooke Ryan, Worrall, L., Sekhon, J., Baker, C., Carragher, M., Bohan, J., Power, E., Rose, M., Simmons-Mackie, N., Togher, L., and Kneebone, I.
- Published
- 2019
24. Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body
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Worrall, L. J., Hong, C., Vuckovic, M., Deng, W., Bergeron, J. R. C., Majewski, D. D, Huang, R. K., Spreter, T., Finlay, B. B., Yu, Z., and Strynadka, N. C. J.
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Salmonella -- Physiological aspects ,Organelles -- Physiological aspects ,Cryoelectron microscopy -- Usage ,Environmental issues ,Science and technology ,Zoology and wildlife conservation - Abstract
Author(s): L. J. Worrall [1]; C. Hong [2]; M. Vuckovic [1]; W. Deng [3]; J. R. C. Bergeron [1]; D. D Majewski [1]; R. K. Huang [2]; T. Spreter [1]; [...]
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- 2016
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25. From Soundwaves to BrainWaves: Investigating the effects of choral singing on recovery from stroke and aphasia
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Matthias, B, Worrall, L, Alston, M, Marley, J, and Allan, C
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- 2013
26. What do people with aphasia think about their health care? Factors influencing satisfaction and dissatisfaction
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Tomkins, B, Siyambalapitiya, S, and Worrall, L
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- 2013
27. Speech pathologistsʼ perceptions of the factors that influence decision-making in acute post-stroke aphasia management: 000
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Foster, A, Worrall, L, Rose, M, and OʼHalloran, R
- Published
- 2012
28. ‘You needed to rehab…families as well’: Rehabilitation goals of family members of people with aphasia: 000
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Davidson, B, Howe, T, Worrall, L, Hersh, D, Sherratt, S, Schumacher, L, and Gilbert, J
- Published
- 2012
29. Exploring the meaning of living successfully with aphasia: The use of photography as an adjunct to interviews in research with individuals with aphasia: 000
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Brown, K, Worrall, L, Davidson, B, and Howe, T
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- 2012
30. From Soundwaves to Brainwaves: investigating the effects of choral singing on stroke and aphasia rehabilitation: 000
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Lannen, B, Worrall, L, Alston, M, Marley, J, and Allan, C
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- 2012
31. The efficacy of community aphasia groups: A systematic review: 000
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Lanyon, L, Rose, M, and Worrall, L
- Published
- 2012
32. Very early aphasia screening and therapy: A knowledge transfer and exchange plan: Session D.6
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Power, E, Godecke, E, OʼHalloran, R, and Worrall, L
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- 2012
33. Communication during hospitalization: the path to better healthcare for children and adults with cerebral palsy: F2.I2
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HEMSLEY, B, BASTOCK, K, BALADIN, S, DAVIDSON, B, SCARINCI, N, and WORRALL, L
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- 2012
34. STRENGTH: STROKE REHABILITATION ENHANCING AND GUIDING TRANSITION HOME: 22204
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Gustafsson, L., Fleming, J., Worrall, L., Brauer, S., Hoyle, M., and Moules, K.
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- 2011
35. RANDOMISED CONTROLLED TRIAL OF A POST-DISCHARGE EDUCATION AND SUPPORT PACKAGE FOR CLIENTS WITH STROKE AND THEIR CARERS: 22203
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Eames, S., Hoffmann, T., Worrall, L., Read, S., and Wong, A.
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- 2011
36. Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
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Zeytuni, N., primary, Dickey, S. W., additional, Hu, J., additional, Chou, H. T., additional, Worrall, L. J., additional, Alexander, J. A. N., additional, Carlson, M. L., additional, Nosella, M., additional, Duong, F., additional, Yu, Z., additional, Otto, M., additional, and Strynadka, N. C. J., additional
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- 2020
- Full Text
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37. Evaluation of an innovative post-discharge education and support package for patients with stroke and their carers: PO10411
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Eames, S, Hoffmann, T, Worrall, L, Wong, A, and Read, S
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- 2010
38. Communication in hospital: views of adults with ID, carers and nurses
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Hemsley, B., Balandin, S., and Worrall, L.
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- 2010
39. RELEASE: A protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia
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Brady, M. C., Ali, M., VandenBerg, K., Williams, L. J., Williams, L. R., Abo, M., Becker, F., Bowen, A., Brandenburg, C., Breitenstein, C., Bruehl, S., Copland, D., Cranfill, T. B., de Pietro-Bachmann, M., Enderby, P., Fillingham, J., Galli, F., Gandolfi, M., Glize, B., Godecke, E., Hawkins, N., Hilari, K., Hinckley, J., Horton, S., Howard, D., Jaecks, P., Jefferies, E., Jesus, L.M.T., Kambanaros, M., Laganaro, M., Lambon Ralph, M. A., Laska, A., Leemann, B., Leff, A.P., Lima, R., Lorenz, A., MacWhinney, B., Shisler Marshall, R., Mattioli, F., Mavis, I., Meinzer, M., Nilipour, R., Noe, E., Paik, N-J., Palmer, R., Papathanasiou, I., Patrício, B., Pavao Martins, I., Price, C. J., Prizl Jakovac, T., Rochon, E., Rose, M., Rosso, C., Rubi-Fessen, I., Ruiter, M. B., Snell, C., Stahl, B., Szaflarski, J., Thomas, S., van de Sandt-Koenderman, M., van der Meulen, I., Visch-Brink, E., Worrall, L., and Harris Wright, H.
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P1 - Abstract
Background: Speech and language therapy (SLT) benefits people with aphasia following stroke. Group level summary statistics from randomised controlled trials hinder exploration of highly complex SLT interventions and a clinically relevant heterogeneous population. Creating a database of individual participant data (IPD) for people with aphasia aims to allow exploration of individual and therapy-related predictors of recovery and prognosis. \ud \ud Aim: To explore the contribution that individual participant characteristics (including stroke and aphasia profiles) and SLT intervention components make to language recovery following stroke.\ud \ud Methods and procedures: We will identify eligible IPD datasets (including randomised controlled trials, non-randomised comparison studies, observational studies and registries) and invite their contribution to the database. Where possible, we will use metaand network meta-analysis to explore language performance after stroke and predictors of recovery as it relates to participants who had no SLT, historical SLT or SLT in the primary research study. We will also examine the components of effective SLT interventions.\ud \ud Outcomes and results: Outcomes include changes in measures of functional communication, overall severity of language impairment, auditory comprehension, spoken language (including naming), reading and writing from baseline. Data captured on assessment tools will be collated and transformed to a standardised measure for each of the outcome domains.\ud \ud Conclusion: Our planned systematic-review-based IPD meta- and network meta-analysis is a large scale, international, multidisciplinary and methodologically complex endeavour. It will enable hypotheses to be generated and tested to optimise and inform development of interventions for people with aphasia after stroke.\ud \ud Systematic review registration: The protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42018110947
- Published
- 2019
40. Real-time monitoring of a 3D cancer model in the RCCS™
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Worrall, L. K., Rose, F. R.A.J., Bradshaw, T. D., Stevens, M. F.G., and Shakesheff, K. M.
- Published
- 2005
41. Barriers and facilitators to meeting aphasia guideline recommendations: what factors influence speech pathologists’ practice?
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Shrubsole, K, Worrall, L, Power, E, O’Connor, DA, Shrubsole, K, Worrall, L, Power, E, and O’Connor, DA
- Abstract
© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Purpose: To explore factors influencing Australian speech pathologists’ guideline recommended aphasia management practices. Methods: Semi-structured interviews were conducted with hospital-based speech pathologists (n = 20). Interviews focused on barriers and facilitators to implementing recommendations related to five practice areas: Aphasia-friendly Information; Collaborative Goal Setting; Timing of Therapy; Amount and Intensity of Therapy; and Conversation Partner Training. Results: Speech pathologists working only in inpatient rehabilitation settings reported performing the recommended behaviours consistently, and identified few implementation barriers. However, clinicians working in the acute setting reported performing the majority of behaviours inconsistently or rarely. Seven (of 14) Theoretical Domains Framework domains were identified as key influencing factors. Three of these–“Environmental Context and Resources,” “Beliefs about Consequences,” and “Social Influences”–were consistently reported as influencing practice across all five behaviours. Other important domains included “Knowledge”, “Beliefs about Capabilities,” “Goals,” and “Social/Professional Role and Identity”, which each influenced at least two practice behaviours. Conclusions: Speech pathologists report a number of key factors influencing their practice, which differ in how they influence behaviours (i.e., a factor may be a barrier or a facilitator) depending on the behaviour and clinical setting. Future implementation interventions need to account for the strong influence of beliefs and social influences on speech pathology practice, which may facilitate successful implementation.Implications for rehabilitation Speech pathologists’ aphasia management practices are often inconsistent with guideline recommendations. Environmental and contextual barriers were identified for all guideline-recommended practices that were investi
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- 2019
42. Closing the evidence-practice gaps in aphasia management: are we there yet? Where has a decade of implementation research taken us? A review and guide for clinicians
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Shrubsole, K, Worrall, L, Power, E, Shrubsole, K, Worrall, L, and Power, E
- Abstract
© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Background: There are evidence-practice gaps in all areas of aphasia management across the continuum of care. Despite the recognition that effective implementation strategies are needed to improve the consistency of speech pathologists’ aphasia management practices, there have been few studies investigating this important issue. Therefore, little is known about the effectiveness of implementation strategies in the field of aphasiology. In light of the developing field of knowledge translation, it is important to review the aphasia implementation literature to highlight current trends, draw together findings, and determine future implementation research needs. Aims: To critically review, summarise, and discuss the implementation literature in the field of aphasiology to date, in order to guide clinical aphasiologists to work towards closing the evidence-practice gaps in aphasia management. Main contribution: A review of the literature in this developing area of expertise in the field of aphasiology, with examples of practical applications. Conclusions: Only six implementation studies have been published in aphasia (related to conversation partner training, discourse analysis, information provision, and collaborative goal-setting practices), showing there is a need for capacity building in this area. Therefore, we are not yet able to state what interventions are effective in which context, nor fully understand how behaviour change occurs for clinicians providing aphasia management. Implications for speech-language pathologists are discussed. An overarching call to action is the need for clinicians and researchers to work together to drive future implementation efforts that can succeed in closing the aphasia management evidence-practice gaps.
- Published
- 2019
43. Increasing the intensity and comprehensiveness of aphasia services: identification of key factors influencing implementation across six countries
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Trebilcock, M, Worrall, L, Ryan, B, Shrubsole, K, Jagoe, C, Simmons-Mackie, N, Bright, F, Cruice, M, Pritchard, M, Le Dorze, G, Trebilcock, M, Worrall, L, Ryan, B, Shrubsole, K, Jagoe, C, Simmons-Mackie, N, Bright, F, Cruice, M, Pritchard, M, and Le Dorze, G
- Abstract
Background: Aphasia services are currently faced by increasing evidence for therapy of greater intensity and comprehensiveness. Intensive Comprehensive Aphasia Programs (ICAPs) combine these elements in an evidence-based, time-limited group program. The incorporation of new service delivery models in routine clinical practice is, however, likely to pose challenges for both the service provider and administering clinicians. This program of research aims to identify these challenges from the perspective of aphasia clinicians from six countries and will seek to trial potential solutions. Continual advancements in global communication technologies suggest that solutions will be easily shared and accessed across multiple countries. Aims: To identify the perceived and experienced barriers and facilitators to the implementation of 1) intensive aphasia services, 2) comprehensive aphasia services, and 3) ICAPs, from aphasia clinicians across six countries. Methods and procedures: A qualitative enquiry approach included data from six focus groups (n = 34 participants) in Australia, New Zealand, Canada, United States of America (USA), United Kingdom (UK), and Ireland. A thematic analysis of focus group data was informed by the Theoretical Domains Framework (TDF). Outcomes and results: Five prominent theoretical domains from the TDF influenced the implementation of all three aphasia service types across participating countries: environmental context and resources, beliefs about consequences, social/professional role and identity, skills, and knowledge. Four overarching themes assisted the identification and explanation of the key barriers and facilitators: 1. Collaboration, joint initiatives and partnerships, 2. Advocacy, the promotion of aphasia services and evidence-based practice, 3. Innovation, the ability to problem solve challenges, and 4. Culture, the influence of underlying values. Conclusions: The results of this study will inform the development of a theoretically inf
- Published
- 2019
44. A systematic review of falls in hospital for patients with communication disability: Highlighting an invisible population
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Hemsley, B, Steel, J, Worrall, L, Hill, S, Bryant, L, Johnston, L, Georgiou, A, Balandin, S, Hemsley, B, Steel, J, Worrall, L, Hill, S, Bryant, L, Johnston, L, Georgiou, A, and Balandin, S
- Abstract
© 2018 The Authors Background: Patients with communication disability, associated with impairments of speech, language, or voice, have a three-fold increased risk of adverse events in hospital. However, little research yet examines the causal relationship between communication disability and risk for specific adverse events in hospital. Objective: To examine the impact of a patient's communication disability on their falls risk in hospital. Methods: This systematic review examined 61 studies on falls of adult hospital patients with communication disability, and patients at high risk of communication disability, to determine whether or not communication disability increased risk for falls, and the nature of and reasons for any increased risk. Results: In total, 46 of the included studies (75%) reported on participants with communication disability, and the remainder included patients with health conditions placing them at high risk for communication disability. Two thirds of the studies examining falls risk identified communication disability as contributing to falls. Commonly, patients with communication disability were actively excluded from participation; measures of communication or cognition were not reported; and reasons for any increased risk of falls were not discussed. Conclusions: There is some evidence that communication disability is associated with increased risk of falls. However, the role of communication disability in falls is under-researched, and reasons for the increased risk remain unclear. Practical applications: Including patients with communication disability in falls research is necessary to determine reasons for their increased risk of adverse events in hospital. Their inclusion might be helped by the involvement of speech-language pathologists in falls research teams.
- Published
- 2019
45. Fidelity protocol for the Action Success Knowledge (ASK) trial: A psychosocial intervention administered by speech and language therapists to prevent depression in people with post-stroke aphasia
- Author
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Carragher, M, Ryan, B, Worrall, L, Thomas, S, Rose, M, Simmons-Mackie, N, Khan, A, Hoffmann, TC, Power, E, Togher, L, Kneebone, I, Carragher, M, Ryan, B, Worrall, L, Thomas, S, Rose, M, Simmons-Mackie, N, Khan, A, Hoffmann, TC, Power, E, Togher, L, and Kneebone, I
- Abstract
© 2019 Author(s) (or their employer(s)). Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Treatment fidelity is a complex, multifaceted evaluative process which refers to whether a studied intervention was delivered as intended. Monitoring and enhancing fidelity is one recommendation of the TiDIER (Template for Intervention Description and Replication) checklist, as fidelity can inform interpretation and conclusions drawn about treatment effects. Despite the methodological and translational benefits, fidelity strategies have been used inconsistently within health behaviour intervention studies; in particular, within aphasia intervention studies, reporting of fidelity remains relatively rare. This paper describes the development of a fidelity protocol for the Action Success Knowledge (ASK) study, a current cluster randomised trial investigating an early mood intervention for people with aphasia (a language disability caused by stroke). Methods and analysis A novel fidelity protocol and tool was developed to monitor and enhance fidelity within the two arms (experimental treatment and attention control) of the ASK study. The ASK fidelity protocol was developed based on the National Institutes of Health Behaviour Change Consortium fidelity framework. Ethics and dissemination The study protocol was approved by the Darling Downs Hospital and Health Service Human Research Ethics Committee in Queensland, Australia under the National Mutual Acceptance scheme of multicentre human research projects. Specific ethics approval was obtained for those participating sites who were not under the National Mutual Agreement at the time of application. The monitoring and ongoing conduct of the research project is in line with requirements under the National Mutual Acceptance. On completion of the trial, findings from the fidelity reviews will be disseminated via publications and conference presentations. Trial registration
- Published
- 2019
46. Time to step up: A call for the speech pathology1 profession to utilise stepped psychological care for people with aphasia post stroke
- Author
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Ryan, B, Worrall, L, Sekhon, J, Baker, C, Carragher, M, Bohan, J, Power, E, Rose, M, Simmons-Mackie, N, Togher, L, Kneebone, I, Ryan, B, Worrall, L, Sekhon, J, Baker, C, Carragher, M, Bohan, J, Power, E, Rose, M, Simmons-Mackie, N, Togher, L, and Kneebone, I
- Published
- 2019
47. A content analysis of documentation on communication disability in hospital progress notes: diagnosis, function, and patient safety
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Steel, J, Georgiou, A, Balandin, S, Hill, S, Worrall, L, Hemsley, B, Steel, J, Georgiou, A, Balandin, S, Hill, S, Worrall, L, and Hemsley, B
- Abstract
© The Author(s) 2019. Objective: To examine the content, quantity, and quality of multidisciplinary team documentation of ‘communication’ in hospital progress notes of patients with communication disability, and to explore the relationship of this documentation to patient safety. Design: Retrospective chart review involving a descriptive analysis and a qualitative content analysis of the progress notes. Setting: Acute medical and rehabilitation wards in two regional hospitals in one health district in Australia. Participants: Eight patients with communication disability who had experienced documented patient safety incidents in hospital. Methods: In total, 906 progress note entries about communication during 38 hospital admissions were extracted from eight patient’s charts; written by staff in 11 different health disciplines. Data were analysed descriptively according to quantity, and qualitatively according to the content. Results: Four content categories of meaning in progress note entries relating to communication were (1) use of communication diagnostic and impairment terms; (2) notes on the patient’s communicative function; (3) reports of the topic or content of the patient’s communication attempts; and (4) references to third parties communicating for the patient. Communication-related information was often brief, unclear, and/or inaccurate. Descriptions of communicative function and recommended strategies for successful communication were often lacking. Conclusion: The suboptimal documentation of patient communication in progress notes may contribute to the higher risk of patient safety incidents for hospital patients with communication disability. Increased accuracy in documenting communication disability and function in progress notes might assist staff in communicating with these patients and improve the quality and safety of their care.
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- 2019
48. Feeding problems in infants with gastro-oesophageal reflux disease: A controlled study
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MATHISEN, B, WORRALL, L, MASEL, J, WALL, C, and SHEPHERD, R W
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- 1999
49. Implementing a tailored behaviour change intervention to improve speech pathologists’ aphasia practices: results of a pilot cluster randomised controlled trial
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Shrubsole, K, Worrall, L, Power, E, and O’Connor, DA
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Speech-Language Pathology & Audiology ,1103 Clinical Sciences, 1109 Neurosciences, 1702 Cognitive Sciences - Published
- 2018
50. Factors that influence Australian speech-language pathologists’ self-reported uptake of aphasia rehabilitation recommendations from clinical practice guidelines
- Author
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Young, L, Shrubsole, K, Worrall, L, and Power, E
- Subjects
Speech-Language Pathology & Audiology - Abstract
© 2018 Informa UK Limited, trading as Taylor & Francis Group. Background: There are clinical practice guidelines for speech-language pathologists’ aphasia management practices. However, reported adherence to aphasia guideline recommendations is variable. The barriers and facilitators to meeting aphasia management recommendations are not well understood. In order to develop theory-informed strategies to improve implementation of aphasia management practices, a better understanding of these barriers and facilitators is required. Aims: This study aimed to describe barriers and facilitators to speech-language pathologists’ uptake and implementation of five prioritised recommended practices for aphasia management. Methods & Procedures: An online survey sought information from Australian speech-language pathologists working with clients with aphasia. The survey focused on five practices including goal setting, information provision, constraint-induced language therapy, timing, and intensity of intervention. The Theoretical Domains Framework was used to design the survey, with several statements generated about factors influencing practice for each domain. Outcomes & Results: Surveys were completed by 63 respondents. The theoretical domain “environmental context and resources” (e.g., “I have insufficient time to engage in…”) was the main perceived barrier for the majority of practices being investigated, whilst the theoretical domain “social/professional role and identity” (e.g., “It is part of my role with the multidisciplinary stroke team to engage in…”) was the main perceived implementation facilitator for all practices. The top three barriers and facilitators varied for each of the five recommended practices being investigated. Across clinical settings, there were commonalities and differences in the perceived barriers and facilitators to implementation. There was a significant correlation between self-reported uptake of all of the aphasia rehabilitation recommendations we investigated and participants’ total barrier scores. Total barrier scores were also significantly different between clinical settings in the area of goal setting, with acute settings having a higher number of reported barriers to goal setting than rehabilitation settings (p = 0.011). Conclusions: Implementation interventions that seek to overcome the barriers of environmental context and resources (time, competing priorities and resources) are likely to have the most effect on aphasia best practice uptake. Encouraging behaviour change in the “social professional role and identity” domain by emphasising the role of the speech-language pathologist in aphasia rehabilitation within the multidisciplinary stroke team should further improve uptake of recommended practices. At a local level, departments or individual speech pathologists need to identify their own barriers and facilitators and choose effective implementation interventions using the Behaviour Change Wheel. Both strategies should help close the evidence-practice gap in aphasia rehabilitation.
- Published
- 2018
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